TLP1: A gene encoding a protein component of mammalian telomerase is a novel member of WD repeats family

Cell

Volumn 88, Issue 6, 1997, Pages 875-884

  Nakayama, Jun Ichi ^a   Saito, Motoki ^a   Nakamura, Hideo ^b   Matsuura, Akira ^a   Ishikawa, Fuyuki ^a  

^a TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

^b MITSUBISHI CHEMICAL CORPORATION   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; TELOMERASE;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; GENE EXPRESSION; HUMAN; MOLECULAR CLONING; MOUSE; PRIORITY JOURNAL; PROTEIN MODIFICATION; PROTEIN STRUCTURE; RAT; SEQUENCE HOMOLOGY; TANDEM REPEAT; TELOMERE;

EID: 0030898989     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(00)81933-9     Document Type: Article

References (47)

1. Avilion, A.A., Piatyszek, M.A., Gupta, J., Shay, J.W., Bacchetti, S., and Greider, C.W. (1996). Human telomerase RNA and telomerase activity in immortal cell lines and tumor tissues. Cancer Res. 56, 645-650.
2. Blackburn, E.H. (1992). Telomerase. Annu. Rev. Biochem. 61, 113-129.
3. Blasco, M.A., Funk, W., Villeponteau, B., and Greider, C.W. (1995). Functional characterization and developmental regulation of mouse telomerase RNA. Science 269, 1267-1270.
4. Chong, L., van Steensel, B., Broccoli, D., Erdjument-Bromage, H., Hanish, J., Tempst, P., and de Lange, T. (1995). A human telomeric protein. Science 270, 1663-1667.
5. Cohn, M., and Blackburn, E.H. (1995). Telomerase in yeast. Science 289, 396-400.
6. Collins, K., Kobayashi, R., and Greider, C.W. (1995). Purification of Tetrahymena telomerase and cloning of genes encoding the two protein components of the enzyme. Cell 81, 677-686.
7. Counter, C.M., Avilion, A.A., LeFeuvre, C.E., Stewart, N.G., Greider, C.W., Harley, C.B., and Bacchetti, S. (1992). Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity. EMBO J. 11, 1921-1929.
8. Fang, G., and Cech, T.R. (1995). Telomere proteins. In Telomeres, E.H. Blackburn and C.W. Greider, eds. (Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press), pp. 69-105.
9. Feng, J., Funk, W.D., Wang, S.-S., Weinrich, S.L., Avilion, A.A., Chiu, C.-P., Adams, R.R., Chang, E., Allsopp, R.C., Yu, J., et al. (1995). The RNA component of human telomerase. Science 269, 1236-1241.
10. Fong, H.K., Hurley, J.B., Hopkins, R.S., Miake-Lye, R., Johnson, M.S., Doolittle, R.F., and Simon, M.I. (1986). Repetitive segmental structure of the transducin β subunit: homology with the CDC4 gene and identification of related mRNAs. Proc. Natl. Acad. Sci. USA 83, 2162-2166.
11. Gottschling, D.E., and Cech, T.R. (1984). Chromatin structure of the molecular ends of Oxytricha macronuclear DNA: phased nucleosomes and a telomeric complex. Cell 38, 501-510.
12. Greider, C.W. (1996). Telomere length regulation. Annu. Rev. Biochem. 65, 337-365.
13. Greider, C.W., and Blackburn, E.H. (1985). Identification of a specific telomere terminal transferase activity in Tetrahymena extracts. Cell 43, 405-413.
14. Greider, C.W., and Blackburn, E.H. (1987). The telomere terminal transferase of Tetrahymena is a ribonucleoprotein enzyme with two kinds of primer specificity. Cell 51, 887-898.
15. Greider, C.W., and Blackburn, E.H. (1989). A telomeric sequence in the RNA of Tetrahymena telomerase required for repeat synthesis. Nature 337, 331-337.
16. Harley, C.B., and Villeponteau, B. (1995). Telomeres and telomerase in aging and cancer. Curr. Opin. Genet. Dev. 5, 249-255.
17. Harley, C.B., Futcher, A.B., and Greider, C.W. (1990). Telomeres shorten during ageing of human fibroblasts. Nature 345, 458-462.
18. Hastie, N.D., Dempster, M., Dunlop, M.G., Thompson, A.M., Green, D.K., and Allshire, R.C. (1990). Telomere reduction in human colorectal carcinoma and with ageing. Nature 346, 866-868.
19. Kim, N.W., Piatyszek, M.A., Prowse, K.R., Harley, C.B., West, M.D., Ho, P.L.C., Coviello, G.M., Wright, W.E., Weinrich, S.L., and Shay, J.W. (1994). Specific association of human telomerase activity with immortal cells and cancer. Science 266, 2011-2015.
20. Krauskopf, A., and Blackburn, E.H. (1996). Control of telomere growth by interaction of RAP1 with the most distal telomeric repeats. Nature 383, 354-357.
21. Levy, M.Z., Allsopp, R.C., Futcher, A.B., Greider, C.W., and Harley, C.B. (1992). Telomere end-replication problem and cell aging. J. Mol. Biol. 225, 951-960.
22. Lin, J.-J., and Zakian, V.A. (1995). An in vitro assay for Saccharomyces telomerase requires EST1. Cell 81, 1127-1135.
23. Lingner, J., and Cech, T.R. (1996). Purification of telomerase from Euplotes aediculatus: requirement of a primer 3′ overhang. Proc. Natl. Acad. Sci. USA 93, 10712-10717.
24. Lingner, J., Hendrick, L.L., and Cech, T.R. (1994). Telomerase RNAs of different ciliates have a common secondary structure and a permuted template. Genes Dev. 8, 1984-1998.
25. Lingner, J., Cooper, J.P., and Cech, T.R. (1995). Telomerase and DNA end replication: no longer a lagging strand problem? Science 269, 1533-1534.
26. Lue, N.F., and Wang, J.C. (1995). ATP-dependent processivity of a telomerase activity from Saccharomyces cerevisiae. J. Biol. Chem. 270, 21453-21456.
27. Mantell, L.L., and Greider, C.W. (1994). Telomerase activity in germline and embryonic cells of Xenopus. EMBO J. 13, 3211-3217.
28. McEachern, M.J., and Blackburn, E.H. (1995). Runaway telomere elongation caused by telomerase RNA gene mutations. Nature 376, 403-409.
29. Morin, G.B. (1989). The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats. Cell 59, 521-529.
30. Moyzis, R.K., Buckingham, J.M., Cram, L.S., Dani, M., Deaven, L.L., Jones, M.D., Meyne, J., Ratliff, R.L., and Wu, J.-R. (1988). A highly conserved repetitive DNA sequence, (TTAGGG)n, present at the telomeres of human chromosomes. Proc. Natl. Acad. Sci. USA 85, 6622-6626.
31. Neer, E.J. (1995). Heterotrimeric G proteins: organizers of transmembrane signals. Cell 80, 249-257.
32. Neer, E.J., Schmidt, C.J., Nambudripad, R., and Smith, T.F. (1994). The ancient regulatory-protein family of WD-repeat proteins. Nature 371, 297-300.
33. Olovnikov, A.M. (1973). A theory of marginotomy. J. Theor. Biol. 41, 181-190.
34. Prowse, K.R., and Greider, C.W. (1995). Developmental and tissue-specific regulation of mouse telomerase and telomere length. Proc. Natl. Acad. Sci. USA 92, 4818-4822.
35. Riley, J., Butler, R., Ogilvie, D., Finnier, R., Jenner, D., Powell, S., Anand, R., Smith, J.C., and Markham, A.F. (1990). A novel, rapid method for the isolation of terminal sequences from yeast artificial chromosome (YAC) clones. Nucleic Acids Res. 18, 2887-2890.
36. Riley, J.H., Albertsen, H., Thliveris, A., Munroe, D.J., and Watkins, P. (1994). Deriving probes from large-insert clones by PCR methods. In Current Protocols in Human Genetics, N.C. Doracopoli, J.L. Hanes, B.R. Korf, D.T. Moir, C.C. Morton, C.E. Seidman, J.G. Seidman, and D.R. Smith, eds. (New York: John Wiley & Sons), pp. 5.9.1-5.9.33.
37. Runge, K.W., and Zakian, V.A. (1989). Introduction of extratelomeric DNA sequences into Saccharomyces cerevisiae results in telomere elongation. Mol. Cell. Biol. 9, 1488-1497.
38. Shippen-Lentz, D., and Blackburn, E. (1990). Functional evidence for an RNA template in telomerase. Science 247, 546-552.
39. Singer, M.S., and Gottschling, D.E. (1994). TLC1: template RNA component of Saccharomyces cerevisiae telomerase. Science 266, 404-409.
40. Sondek, J., Bohm, A., Lambright, D.G., Hamm, H.E., and Sigler, P.B. (1996). Crystal structure of a G protein βγ dimer at 2.1 Å resolution. Nature 379, 369-374.
41. Tatematsu, K., Nakayama, J., Danbara, M., Shionoya, S., Sato, H., ine, M., and Ishikawa, F. (1996). A novel quantitative "stretch PCR assay," that detects a dramatic increase in telomerase activity during the progression of myeloid leukemias. Oncogene 13, 2265-2274.
42. Tommerup, H., Dousmanis, A., and de Lange, T. (1994). Unusual chromatin in human telomeres. Mol. Cell. Biol. 14, 5777-5785.
43. Walker, J.E., Saraste, M., Runswick, M.J., and Gay, N.J. (1982). Distantly related sequences in the alpha-and beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold. EMBO J. 1, 945-951.
44. 1γ2. Cell 83, 1047-1058.
45. Watson, J.D. (1972). Origin of concatemeric T7 DNA. Nature New Biol. 239, 197-201.
46. Wright, J.H., and Zakian, V.A. (1995). Protein-DNA interactions in soluble telosomes from Saccharomyces cerevisiae. Nucleic Acids Res. 23, 1454-1460.
47. Wright, J.H., Gottschling, D.E., and Zakian, V.A. (1992). Saccharomyces telomeres assume a non-nucleosomal chromatin structure. Genes Dev. 6, 197-210.