메뉴 건너뛰기




Volumn 3, Issue 3, 2000, Pages 243-269

Nucleic acids for recognition and catalysis: Landmarks, limitations, and looking to the future

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; CAFFEINE; NUCLEIC ACID; THEOPHYLLINE;

EID: 0033936362     PISSN: 13862073     EISSN: None     Source Type: Journal    
DOI: 10.2174/1386207003331599     Document Type: Article
Times cited : (6)

References (151)
  • 1
  • 18
    • 85037961598 scopus 로고    scopus 로고
    • note
    • 12 cells, thousands of liters would be required.
  • 19
    • 85037958133 scopus 로고    scopus 로고
    • note
    • 36kg is roughly a million times the mass of the sun
  • 23
    • 85037951315 scopus 로고    scopus 로고
    • note
    • 15 fold increase
  • 24
    • 85037969830 scopus 로고    scopus 로고
    • note
    • Most selections work with 200-1000pmol of reamplified material however 200nmol is feasible.
  • 114
    • 0029832218 scopus 로고    scopus 로고
    • Erratum Nature 1996, 383, 192
    • Ekland E.H.; Bartel D.P. Nature, 1996, 382, 373-6;. See Erratum Nature 1996, 383, 192.
    • (1996) Nature , vol.382 , pp. 373-376
    • Ekland, E.H.1    Bartel, D.P.2
  • 143
    • 85037956895 scopus 로고    scopus 로고
    • note
    • Not absolutely true, use of error-prone polymerases that tolerate modified bases may result in misincorporation events leading to heterogeneous species.
  • 150
    • 85037965680 scopus 로고    scopus 로고
    • note
    • This might not be the case when there is serendipitous stabilization of an outcome that would not otherwise be kinetically or thermodynamically favored in the uncatalyzed case. Since nucleic acids present chiral surfaces, it's not unreasonable to propose an over-representation of catalysts that stabilize unfavored outcomes but this is not likely to be readily predictable; by the same reasoning, underrepresentation is equally possible.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.