Solution structure of an ATP-binding RNA aptamer reveals a novel fold

RNA

Volumn 2, Issue 7, 1996, Pages 628-640

  Dieckmann, Thorsten ^a   Suzuki, Ellen ^a   Nakamura, Gerald K ^a   Feigon, Juli ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

2D NMR; AMP; ATP; G G base pair; GNRA tetraloop; in vitro selection; NMR; SELEX; U turn

Indexed keywords

ADENOSINE PHOSPHATE; ADENOSINE TRIPHOSPHATE; NUCLEOTIDE; RNA;

ARTICLE; COMPLEX FORMATION; CONSENSUS SEQUENCE; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; RNA BINDING; RNA STRUCTURE;

ADENOSINE MONOPHOSPHATE; ADENOSINE TRIPHOSPHATE; BINDING SITES; CONSERVED SEQUENCE; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; NUCLEIC ACID CONFORMATION; RNA;

EID: 0029904020     PISSN: 13558382     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (13)

1. Allain F, Varani G. 1995. Structure of the P1 helix from group I self-splicing introns. J Mol Biol 250:333-353.
2. Batey RT, Inada M, Kujawinski E, Puglisi JD, Williamson JR. 1992. Preparation of isotopically labeled ribonucleotides for multidimensional NMR spectroscopy of RNA. Nucleic Acids Res 20:4515-4523.
3. 13C-enriched proteins. J Magn Reson 88:425-431.
4. Bax A, Davis DG. 1985. MLEV-17-based two-dimensional homonuclear magnetization transfer spectroscopy. J Magn Res 65:355-360.
5. Bothner-By AA, Stephens RL, Lee Jm, Warren CD, Jeanloz RW. 1984. Structure determination of a tetrasaccharide: Transient nuclear Overhauser effect in the rotating frame. J Am Chem Soc 106:811-813.
6. Brunger AT. 1992. X-PLOR (version 3.1) manual. New Haven, Connecticut/London: Yale University Press.
7. Burgstaller P, Famulok M. 1994. Isolation of RNA aptamers for biological cofactors by in vitro selection. Angew Chem Int Ed Engl 33:1084-1087.
8. 13C resonances of interleukin-1β using double- and triple-resonance heteronuclear three-dimensional NMR spectroscopy. Biochemistry 29:8172-8184.
9. Dieckmann T, Feigon J. 1994. Heteronuclear techniques in NMR studies of RNA and DNA. Curr Opin Struct Biol 4:745-749.
10. Ellington AD, Szostak JW. 1990. In vitro selection of RNA molecules that bind specific ligands. Nature 346:818-822.
11. Fan P, Suri AK, Fiala R, Live D, Patel DJ. 1996. Molecular recognition in the FMN-RNA aptamer complex. J Mol Biol 258:480-500.
12. Fesik SW, Zuiderweg ERP. 1988. Heteronuclear three-dimensional NMR spectroscopy. A strategy for the simplification of homonuclear two-dimensional NMR spectra. J Magn Reson 75:588-593.
13. 1H proximities. Bull Math Biol 46:673- 698.