RNA-catalysed nucleotide synthesis

Nature

Volumn 395, Issue 6699, 1998, Pages 260-263

  Unrau, Peter J ^a   Bartel, David P ^a  

^a WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RNA;

AMINO ACID SEQUENCE; ARTICLE; NUCLEOTIDE METABOLISM; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DETERMINATION; PROTEIN ISOLATION; PROTEIN SYNTHESIS; SEQUENCE ANALYSIS;

BIOGENESIS; CATALYSIS; CHROMATOGRAPHY, THIN LAYER; MOLECULAR SEQUENCE DATA; NUCLEOTIDES; PYRIMIDINES; RIBOSE; RNA, CATALYTIC; THIOURACIL; THIOURIDINE;

EID: 0032541654     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/26193     Document Type: Article

References (30)

1. Joyce, G. F. & Orgel, L. E. in The RNA World (eds Gesteland, R. F. & Atkins, J. F.) 1-25 (Cold Spring Harbor Lab., Cold Spring Harbor, NY, 1993).
2. Fuller, W. D., Sanchez, R. A. & Orgel, L. E. Studies in prebiotic synthesis VI. Synthesis of purine nucleosides. J. Mol. Biol. 67, 25-33 (1972).
3. Fuller, W. D., Sanchez, R. A. & Orgel, L. E. Studies in prebiotic synthesis VII. Solid-state synthesis of purine nucleosides. J. Mol. Evol. 1, 249-257 (1972).
4. Larralde, R., Robertson, M. P. & Miller, S. L. Rates of decomposition of ribose and other sugars: implications for chemical evoution. Proc. Natl Acad. Sci. USA 92, 8158-8160 (1995).
5. Mizuno, T. & Weiss, A. H. Synthesis and utilization of formose sugars. Adv. Carbohyd. Chem. Biochem. 29, 173-227 (1974).
6. Pitsch, S., Eschenmoser, A., Gedulin, B., Hui, S. & Arrhenius, G. Mineral induced formation of sugar phosphates. Origin Life Evol. Biosphere 25, 297-334 (1995).
7. Oro, J. Mechanism of synthesis of adenine from hdyrogen cyanide under possible primitive earth conditions. Nature 191, 1193-1194 (1961).
8. Sanchez, R. A., Ferris, J. P. & Orgel, L. E. Studies in prebiotic synthesis. II. Synthesis of purine precursors and amino acids from aqueous hydrogen cyanide. J. Mol. Biol. 30, 223-253 (1967).
9. Ferris, J. P., Sanchez, R. A. & Orgel, L. E. Studies in prebiotic synthesis. 3. Synthesis of pyrimidines from cyanoacetylene and cyanate. J. Mol. Biol. 33, 693-704 (1968).
10. Stoks, P. G. & Schwartz, A. W. Uracil in carbonaceous meteorites. Nature 282, 709-710 (1979).
11. Robertson, M. P. & Miller, S. L. An efficient prebiotic synthesis of cytosine and uracil. Nature 375, 772-774 (1995).
12. Bhatia, M. B., Vinitsky, A. & Grubmeyer, C. Kinetic mechanism of orotate phosphoribosyltransferase from Salmonella typhimurium. Biochemistry 29, 10480-10487 (1990).
13. Tao, W., Grubmeyer, C. & Blanchard, J. S. Transition state structure of Salmonella typhimurium orotate phosphoribosyltransferase. Biochemistry 35, 14-21 (1996).
14. Igloi, G. L. Interaction of tRNAs and of phosphorothioate-substituted nucleic acids with an organomercurial. Probing the chemical environment of thiolated residues by affinity electrophoresis. Biochemistry 27, 3842-3849 (1988).
15. Wierzchowski, K. L., Litonska, E. & Shugar, D. Infrared and ultraviolet studies on the tautomeric equilibria in aqueous medium between monoanionic species of uracil, thymine, 5-fluorouracil, and other 2,4-diketopyrimidines. J. Am. Chem. Soc. 87, 4621-4629 (1965).
16. Psoda, A., Kazimierczuk, Z. & Shugar, D. Structure and tautomerism of the neutral and monoanionic forms of 4-thiouracil derivatives. J. Am. Chem. Soc. 96, 6832-6839 (1974).
17. Bartel, D. P. & Szostak, J. W. Isolation of new ribozymes from a large pool of random sequences. Science 261, 1411-1418 (1993).
18. Gray, M. W. The presence of 2′-O-methylpseudouridine in the 18S + 26S ribosomal ribonucleates of wheat embryo. Biochemistry 13, 5453-5463 (1974).
19. Jaffe, E. K. & Cohn, M. Diastereomers of the nucleoside phosphorothioates as probes of the structure of the metal nucleotide substrates and of the nucleotide binding site of yeast hexokinase. J. Biol. Chem. 254, 10839-10845 (1979).
20. Benner, S. A., Ellington, A. D. & Tauer, A. Modern metabolism as a palimpsest of the RNA world. Proc. Natl Acad. Sci. USA 86, 7054-7058 (1989).
21. Michel, F., Hanna, M., Green, R., Bartel, D. P. & Szostak, J. W. The guanosine binding site of the Tetrahymena ribozyme. Nature 342, 391-395 (1989).
22. Been, M. D. & Perrotta, A. T. Group I intron self-splicing with adenosine: evidence for a single nucleoside-binding site. Science 252, 434-437 (1991).
23. Gold, L., Polisky, B., Uhlenbeck, O. & Yarus, M. Diversity of oligonucleotide functions. Annu. Rev. Biochem. 64, 763-797 (1995).
24. Eldand, E. H. & Bartel, D. P. RNA-catalysed RNA polymerization using nucleoside triphosphates. Nature 382, 373-376 (1996).
25. Ekland, E. H. & Bartel, D. P. The secondary structure and sequence optimization of an RNA ligase ribozyme. Nucleic Acids Res. 23, 3231-3238 (1995).
26. England, T. E., Gumport, R. I. & Uhlenbeck, O. C. Dinucleoside pyrophosphates are substrates for T4-induced RNA ligase. Proc. Natl Acad. Sci. USA 74, 4839-4842 (1977).
27. Lohrmann, R. & Orgel, L. E. Preferential formation of (2′-5′)-linked internucleotide bonds in non-enzymatic reactions. Tetrahedron 34, 853-855 (1978).
28. Santoro, S. W. & Joyce, G. F. A general purpose RNA-cleaving DNA enzyme. Proc. Natl Acad. Sci. USA 94, 4262-4266 (1997).
29. Mizuno, Y., Ikehara, M. & Watanabe, K. A. Potential antimetabolites. I. Selective thiation of uracil and 1,2,4-triazine-3,5(2H,4H)-dione (6-azauracil). Chem. Pharmac. Bull. 10, 647-652 (1962).
30. Wecker, M., Smith, D. & Gold, L. In vitro selection of a novel catalytic RNA: characterization of a sulfur alkylation reaction and interaction with a small peptide. RNA 2, 982-994 (1996).