-
1
-
-
0029558004
-
Cationic liposome-mediated gene transfer
-
Gao X, Huang L: Cationic liposome-mediated gene transfer. Gene Ther (1995) 2:710-722.
-
(1995)
Gene Ther
, vol.2
, pp. 710-722
-
-
Gao, X.1
Huang, L.2
-
3
-
-
0031970246
-
From genes to gene medicines: Recent advances in nonviral gene delivery
-
Rolland AP: From genes to gene medicines: recent advances in nonviral gene delivery. Crit Rev Ther Drug Carrier Syst (1998) 15:143-198.
-
(1998)
Crit Rev Ther Drug Carrier Syst
, vol.15
, pp. 143-198
-
-
Rolland, A.P.1
-
4
-
-
0029147628
-
Nonviral gene therapy: The promise of genes as pharmaceutical products
-
Ledley FD: Nonviral gene therapy: the promise of genes as pharmaceutical products. Hum Gene Ther (1995) 6:1129-1144.
-
(1995)
Hum Gene Ther
, vol.6
, pp. 1129-1144
-
-
Ledley, F.D.1
-
5
-
-
8244245761
-
Evidence for safety and efficacy of DOTAP cationic liposome mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis
-
Porteous DJ, Dorin JR, McLachlan G, Davidson-Smith H, Davidson H, Stevenson BJ, Carothers AD, Wallace WA, Moralee S, Hoenes C, Kallmeyer G, Michaelis U, Naujoks K, Ho LP, Samways JM, Imrie M, Greening AP, Innes JA: Evidence for safety and efficacy of DOTAP cationic liposome mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis. Gene Ther (1997) 4:210-218.
-
(1997)
Gene Ther
, vol.4
, pp. 210-218
-
-
Porteous, D.J.1
Dorin, J.R.2
McLachlan, G.3
Davidson-Smith, H.4
Davidson, H.5
Stevenson, B.J.6
Carothers, A.D.7
Wallace, W.A.8
Moralee, S.9
Hoenes, C.10
Kallmeyer, G.11
Michaelis, U.12
Naujoks, K.13
Ho, L.P.14
Samways, J.M.15
Imrie, M.16
Greening, A.P.17
Innes, J.A.18
-
6
-
-
8244238394
-
A placebo-controlled study of liposome-mediated gene transfer to the nasal epithelium of patients with cystic fibrosis
-
Gill DR, Southern KW, Mofford KA, Seddon T, Huang L, Sorgi F, Thomson A, MacVinish LJ, Ratcliff R, Bilton D, Lane DJ, Littlewood JM, Webb AK, Middleton PG, Colledge WH, Cuthbert AW, Evans MJ, Higgins CF, Hyde SC: A placebo-controlled study of liposome-mediated gene transfer to the nasal epithelium of patients with cystic fibrosis. Gene Ther (1997) 4:199-209.
-
(1997)
Gene Ther
, vol.4
, pp. 199-209
-
-
Gill, D.R.1
Southern, K.W.2
Mofford, K.A.3
Seddon, T.4
Huang, L.5
Sorgi, F.6
Thomson, A.7
MacVinish, L.J.8
Ratcliff, R.9
Bilton, D.10
Lane, D.J.11
Littlewood, J.M.12
Webb, A.K.13
Middleton, P.G.14
Colledge, W.H.15
Cuthbert, A.W.16
Evans, M.J.17
Higgins, C.F.18
Hyde, S.C.19
-
7
-
-
0027517321
-
Direct gene transfer with DNA-liposome complexes in melanoma: Expression, biologic activity, and lack of toxicity in humans
-
Nabel GJ, Nabel EG, Yang ZY, Fox BA, Plautz GE, Gao X, Huang L, Shu S, Gordon D, Chang AE: Direct gene transfer with DNA-liposome complexes in melanoma: expression, biologic activity, and lack of toxicity in humans. Proc Natl Acad Sci USA (1993) 90:11307-11311.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 11307-11311
-
-
Nabel, G.J.1
Nabel, E.G.2
Yang, Z.Y.3
Fox, B.A.4
Plautz, G.E.5
Gao, X.6
Huang, L.7
Shu, S.8
Gordon, D.9
Chang, A.E.10
-
8
-
-
0031032759
-
Phase I study of direct gene transfer of an allogeneic histocompatibility antigen, HLA-B7, in patients with metastatic melanoma
-
Stopeck AT, Hersh EM, Akporiaye ET, Harris DT, Grogan T, Unger E, Wameke J, Schluter SF, Stahl S: Phase I study of direct gene transfer of an allogeneic histocompatibility antigen, HLA-B7, in patients with metastatic melanoma. J Clin Oncol (1997) 15:341-349. This study demonstrates cationic lipid-mediated intratumoral gene transfer of an HLA alloantigen into melanoma patients. An anti-HLA-B7 CTL response is demonstrated.
-
(1997)
J Clin Oncol
, vol.15
, pp. 341-349
-
-
Stopeck, A.T.1
Hersh, E.M.2
Akporiaye, E.T.3
Harris, D.T.4
Grogan, T.5
Unger, E.6
Wameke, J.7
Schluter, S.F.8
Stahl, S.9
-
9
-
-
0028403237
-
Viral vector systems for gene therapy
-
Jolly D: Viral vector systems for gene therapy. Cancer Gene Ther (1994) 1:51-64.
-
(1994)
Cancer Gene Ther
, vol.1
, pp. 51-64
-
-
Jolly, D.1
-
10
-
-
0011652835
-
Cationic liposome systems in gene therapy
-
Miller AD: Cationic liposome systems in gene therapy. Curr Res Molecular Ther (1998) 1:494-503.
-
(1998)
Curr Res Molecular Ther
, vol.1
, pp. 494-503
-
-
Miller, A.D.1
-
11
-
-
0025949812
-
Adenovirus enhancement of transferrin-polylysine-mediated gene delivery
-
Curiel DT, Agarwal S, Wagner E, Cotten M: Adenovirus enhancement of transferrin-polylysine-mediated gene delivery. Proc Natl Acad Sci USA (1991) 88:8850-8854. Describes a novel, hybrid gene transfer method of delivering plasmid DNA employing adenovirus-mediated endocytosis and endosomal rupture.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 8850-8854
-
-
Curiel, D.T.1
Agarwal, S.2
Wagner, E.3
Cotten, M.4
-
12
-
-
0025447655
-
Safety considerations in somatic gene therapy of human disease with retro virus vectors
-
Temin HM: Safety considerations in somatic gene therapy of human disease with retro virus vectors. Hum Gene Ther (1990) 1:111-123.
-
(1990)
Hum Gene Ther
, vol.1
, pp. 111-123
-
-
Temin, H.M.1
-
13
-
-
0028170362
-
Prospects for the use of adeno-assoclated virus as a vector for human gene therapy
-
Kotin RM: Prospects for the use of adeno-assoclated virus as a vector for human gene therapy. Hum Gene Ther (1994) 5:793-801.
-
(1994)
Hum Gene Ther
, vol.5
, pp. 793-801
-
-
Kotin, R.M.1
-
14
-
-
0028526161
-
Herpes simplex virus vectors for gene therapy
-
Latchman DS: Herpes simplex virus vectors for gene therapy. Mol Biotechnol (1994) 2:179-195.
-
(1994)
Mol Biotechnol
, vol.2
, pp. 179-195
-
-
Latchman, D.S.1
-
15
-
-
0029996147
-
In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector
-
Naldini L, Blömer U, Gallay P, Ory D, Mulligan R, Gage FH, Verma IM, Trono D: In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector. Science (1996) 272:263-267. Describes construction and potential uses of lentivirus gene vectors, which are capable of delivering and integrating transgenes into nondividing lymphoid and myeloid cells.
-
(1996)
Science
, vol.272
, pp. 263-267
-
-
Naldini, L.1
Blömer, U.2
Gallay, P.3
Ory, D.4
Mulligan, R.5
Gage, F.H.6
Verma, I.M.7
Trono, D.8
-
16
-
-
9244220682
-
Immune responses to viral antigens versus transgene product in the elimination of recombinant adenovirus-infected hepatocytes in vivo
-
Yang Y, Jooss KU, Su Q, Ertl HC, Wilson JM: Immune responses to viral antigens versus transgene product in the elimination of recombinant adenovirus-infected hepatocytes in vivo. Gene Ther (1996) 3:137-144. Reveals the potential problems associated with adenovirus gene transfer and defines immunoreactive antigens of viral and exogenous origin that may play a role in limiting transgene expression.
-
(1996)
Gene Ther
, vol.3
, pp. 137-144
-
-
Yang, Y.1
Jooss, K.U.2
Su, Q.3
Ertl, H.C.4
Wilson, J.M.5
-
17
-
-
0028991828
-
Protection of retroviral vector particles in human blood through complement inhibition
-
Rother RP, Squinto SP, Mason JM, Rollins SA: Protection of retroviral vector particles in human blood through complement inhibition. Hum Gene Ther (1995) 6:429-435.
-
(1995)
Hum Gene Ther
, vol.6
, pp. 429-435
-
-
Rother, R.P.1
Squinto, S.P.2
Mason, J.M.3
Rollins, S.A.4
-
18
-
-
0032549625
-
Selective gene transfer into the liver of non-human primates with E1-deleted, E2A-defective, or E1-E4 deleted recombinant adenoviruses
-
Raper SE, Haskal ZJ, Ye X, Pugh C, Furth EE, Gao GP, Wilson JM: Selective gene transfer into the liver of non-human primates with E1-deleted, E2A-defective, or E1-E4 deleted recombinant adenoviruses. Hum Gene Ther (1998) 9:671-679
-
(1998)
Hum Gene Ther
, vol.9
, pp. 671-679
-
-
Raper, S.E.1
Haskal, Z.J.2
Ye, X.3
Pugh, C.4
Furth, E.E.5
Gao, G.P.6
Wilson, J.M.7
-
19
-
-
0015847039
-
A new technique for the assay of infectivity of human adenovirus 5 DNA
-
Graham FL, Van Der Eb AJ: A new technique for the assay of infectivity of human adenovirus 5 DNA. Virology (1973) 52:456-467.
-
(1973)
Virology
, vol.52
, pp. 456-467
-
-
Graham, F.L.1
Van Der Eb, A.J.2
-
20
-
-
0021721736
-
Direct transfection of viral and plasmid DNA into the liver or spleen of mice
-
Dubensky TW, Campbell BA, Villarrreal LP: Direct transfection of viral and plasmid DNA into the liver or spleen of mice. Proc Natl Acad Sci USA (1984) 81:7529-7533.
-
(1984)
Proc Natl Acad Sci USA
, vol.81
, pp. 7529-7533
-
-
Dubensky, T.W.1
Campbell, B.A.2
Villarrreal, L.P.3
-
21
-
-
0342493581
-
Efficient infection of monkey cells with DNA of simian virus 40
-
Sompayrac LM, Danna KJ: Efficient infection of monkey cells with DNA of simian virus 40. Proc Natl Acad Sci USA (1981) 78:7575-7578.
-
(1981)
Proc Natl Acad Sci USA
, vol.78
, pp. 7575-7578
-
-
Sompayrac, L.M.1
Danna, K.J.2
-
22
-
-
0025231388
-
Direct gene transfer into mouse muscle in vivo
-
Wolfe JA, Malone RW, Williams P, Chong W, Acsadi G, Jani A, Felgner PL: Direct gene transfer into mouse muscle in vivo. Science (1990) 247:1465-1468. Initial report demonstrating the feasibility of 'naked' plasmid DNA gene transfer in muscle tissue.
-
(1990)
Science
, vol.247
, pp. 1465-1468
-
-
Wolfe, J.A.1
Malone, R.W.2
Williams, P.3
Chong, W.4
Acsadi, G.5
Jani, A.6
Felgner, P.L.7
-
23
-
-
0027713229
-
Gene therapy by intramuscular injection of plasmid DNA: Studies on firefly luciferase gene expression in mice
-
Manthorpe M, Comefert-Jensen F, Hartikka J, Felgner J, Rundell A, Margalith M, Dwarki V: Gene therapy by intramuscular injection of plasmid DNA: studies on firefly luciferase gene expression in mice. Hum Gene Ther (1993) 4:419-431.
-
(1993)
Hum Gene Ther
, vol.4
, pp. 419-431
-
-
Manthorpe, M.1
Comefert-Jensen, F.2
Hartikka, J.3
Felgner, J.4
Rundell, A.5
Margalith, M.6
Dwarki, V.7
-
24
-
-
19144367904
-
An improved plasmid DNA expression vector for direct injection into skeletal muscle
-
Hartikka J, Sawdey M, Comefert-Jensen F, Margalith M, Barnhart K, Nolasco M, Vahlsing HL, Meek J, Marquet M, Hobart P, Norman J, Manthorpe M: An improved plasmid DNA expression vector for direct injection into skeletal muscle. Hum Gene Ther (1996) 7:1205-1217. This study reveals the impact of plasmid DNA optimization and emphasizes key regulatory elements that contribute to successful plasmid construction.
-
(1996)
Hum Gene Ther
, vol.7
, pp. 1205-1217
-
-
Hartikka, J.1
Sawdey, M.2
Comefert-Jensen, F.3
Margalith, M.4
Barnhart, K.5
Nolasco, M.6
Vahlsing, H.L.7
Meek, J.8
Marquet, M.9
Hobart, P.10
Norman, J.11
Manthorpe, M.12
-
25
-
-
0029160083
-
A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: Polyethylenimine
-
Boussif O, Lezoualc'h F, Zanta MA, Mergny MD, Scherman D, Demeneix B, Behr JP: A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine. Proc Natl Acad Sci USA (1995) 92:7297-7301.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 7297-7301
-
-
Boussif, O.1
Lezoualc'h, F.2
Zanta, M.A.3
Mergny, M.D.4
Scherman, D.5
Demeneix, B.6
Behr, J.P.7
-
26
-
-
0027655718
-
Polyamidoamine cascade polymers mediate efficient transfection of cells in culture
-
Haensler J, Szoka FC Jr: Polyamidoamine cascade polymers mediate efficient transfection of cells in culture. Bioconjug Chem (1993) 4:372-379.
-
(1993)
Bioconjug Chem
, vol.4
, pp. 372-379
-
-
Haensler, J.1
Szoka Jr., F.C.2
-
27
-
-
0025340966
-
Transferrin-polycation conjugates as carriers for DNA uptake into cells
-
Wagner E, Zenke M, Cotten M, Beug H, Birnstiel ML: Transferrin-polycation conjugates as carriers for DNA uptake into cells. Proc Natl Acad Sci USA (1990) 87:3410-3414.
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 3410-3414
-
-
Wagner, E.1
Zenke, M.2
Cotten, M.3
Beug, H.4
Birnstiel, M.L.5
-
28
-
-
0023447252
-
Lipofection: A highly efficient, lipid-mediated DNA-transfection procedure
-
Felgner PL, Gadek TR, Holm M, Roman R, Chan HW, Wenz M, Northrop JP, Ringold GM, Danielsen M: Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure. Proc Natl Acad Sci USA (1987) 84:7413-7417. Original report describing the methods and reagents used to deliver plasmid DNA with cationic lipids.
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 7413-7417
-
-
Felgner, P.L.1
Gadek, T.R.2
Holm, M.3
Roman, R.4
Chan, H.W.5
Wenz, M.6
Northrop, J.P.7
Ringold, G.M.8
Danielsen, M.9
-
29
-
-
0031551024
-
Biophysical characterization of cationic lipid: DNA complexes
-
Eastman SJ, Siegal C, Tousignant J, Smith AE, Cheng SH, Scheule RK: Biophysical characterization of cationic lipid: DNA complexes. Biochim Biophys Acta (1997) 1325:41-62.
-
(1997)
Biochim Biophys Acta
, vol.1325
, pp. 41-62
-
-
Eastman, S.J.1
Siegal, C.2
Tousignant, J.3
Smith, A.E.4
Cheng, S.H.5
Scheule, R.K.6
-
30
-
-
0027179724
-
Mode of formation and structural features of DNA-cationic liposome complexes used for transfection
-
Gershon H, Ghirlando R, Guttman SB, Minsky A: Mode of formation and structural features of DNA-cationic liposome complexes used for transfection. Biochemistry (1993) 32:7143-7151. Discussions and electron photomicrographs concerning of the cooperative nature of cationic lipid and plasmid DNA interactions. A proposed model of DNA encapsulation and impact on DNA transfer efficiency.
-
(1993)
Biochemistry
, vol.32
, pp. 7143-7151
-
-
Gershon, H.1
Ghirlando, R.2
Guttman, S.B.3
Minsky, A.4
-
31
-
-
0028222954
-
Efficient and sustained gene expression in primary T lymphocytes and primary and cultured tumor cells mediated by adeno-associated virus plasmid DNA complexed to cationic liposomes
-
Philip R, Brunette E, Kilinski L, Murugesh D, McNally MA, Ucar K, Rosenblatt J, Okarma TB, Lebkowski JS: Efficient and sustained gene expression in primary T lymphocytes and primary and cultured tumor cells mediated by adeno-associated virus plasmid DNA complexed to cationic liposomes. Mol Cell Biol (1994) 14:2411-2418.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 2411-2418
-
-
Philip, R.1
Brunette, E.2
Kilinski, L.3
Murugesh, D.4
McNally, M.A.5
Ucar, K.6
Rosenblatt, J.7
Okarma, T.B.8
Lebkowski, J.S.9
-
33
-
-
0032522132
-
Phosphorothioate oligodeoxyribonucleotides dissociate from cationic lipids before entering the nucleus
-
Marcusson EG, Bhat B, Manoharan M, Bennett CF, Dean NM: Phosphorothioate oligodeoxyribonucleotides dissociate from cationic lipids before entering the nucleus. Nucleic Acid Res (1998) 26:2016-2023. Fluorescent labeling of cationic lipid and oligonucleotides reveal intracellular localization and suggest that cationic lipid uncoating occurs in the cytoplasm, prior to nuclear translocation.
-
(1998)
Nucleic Acid Res
, vol.26
, pp. 2016-2023
-
-
Marcusson, E.G.1
Bhat, B.2
Manoharan, M.3
Bennett, C.F.4
Dean, N.M.5
-
35
-
-
0026732781
-
Cationic lipids direct a viral glycoprotein into the class I major histocompatibility complex antigen-presentation pathway
-
Walker C, Selby M, Erickson A, Cataldo D, Valensi JP, Van Nest GV: Cationic lipids direct a viral glycoprotein into the class I major histocompatibility complex antigen-presentation pathway. Proc Natl Acad Sci USA (1992) 89:7915-7918.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 7915-7918
-
-
Walker, C.1
Selby, M.2
Erickson, A.3
Cataldo, D.4
Valensi, J.P.5
Van Nest, G.V.6
-
36
-
-
0028024919
-
Enhanced gene delivery and mechanism studies with a novel series of cationic lipid formulations
-
Felgner JH, Kumar R, Sridhar CN, Wheeler CJ, Tsai YJ, Border R, Ramsey P, Martin M, Felgner PL: Enhanced gene delivery and mechanism studies with a novel series of cationic lipid formulations. J Biol Chem (1994) 269:2550-2561.
-
(1994)
J Biol Chem
, vol.269
, pp. 2550-2561
-
-
Felgner, J.H.1
Kumar, R.2
Sridhar, C.N.3
Wheeler, C.J.4
Tsai, Y.J.5
Border, R.6
Ramsey, P.7
Martin, M.8
Felgner, P.L.9
-
37
-
-
0029067792
-
The role of dioleoyl phosphatidylethanolamine in cationic liposome mediated gene transfer
-
Farhood H, Serbina N, Huang L: The role of dioleoyl phosphatidylethanolamine in cationic liposome mediated gene transfer. Biochim Biophys Acta (1995) 1235:289-295. Study describing the impact of membrane destabilizing co-lipids on the process of lipid-mediated gene transfer. A model of gene transfer via endocytosis is described.
-
(1995)
Biochim Biophys Acta
, vol.1235
, pp. 289-295
-
-
Farhood, H.1
Serbina, N.2
Huang, L.3
-
38
-
-
0032479572
-
An inverted hexagonal phase of cationic liposome-DNA complexes related to DNA release and delivery
-
Koltover I, Salditt T, Rädler JO, Safinya CR: An inverted hexagonal phase of cationic liposome-DNA complexes related to DNA release and delivery. Science (1998) 281:78-81.
-
(1998)
Science
, vol.281
, pp. 78-81
-
-
Koltover, I.1
Salditt, T.2
Rädler, J.O.3
Safinya, C.R.4
-
39
-
-
0028097638
-
DNA transfection mediated by cationic liposomes containing lipopolylysine: Characterization and mechanism of action
-
Zhou X, Huang L: DNA transfection mediated by cationic liposomes containing lipopolylysine: characterization and mechanism of action. Biochim Biophys Acta (1994) 1189:195-203.
-
(1994)
Biochim Biophys Acta
, vol.1189
, pp. 195-203
-
-
Zhou, X.1
Huang, L.2
-
40
-
-
0030794696
-
Effect of co-lipids in enhancing cationic lipid-mediated gene transfer in vitro and in vivo
-
Fasbender A, Marshall J, Moninger TO, Grunst T, Cheng S, Welsh MJ: Effect of co-lipids in enhancing cationic lipid-mediated gene transfer in vitro and in vivo. Gene Ther (1997) 4:716-725.
-
(1997)
Gene Ther
, vol.4
, pp. 716-725
-
-
Fasbender, A.1
Marshall, J.2
Moninger, T.O.3
Grunst, T.4
Cheng, S.5
Welsh, M.J.6
-
41
-
-
0028072689
-
New structures in complex formation between DNA and cationic liposomes visualized by freeze-fracture electron microscopy
-
Sternberg B, Sorgi FL, Huang L: New structures in complex formation between DNA and cationic liposomes visualized by freeze-fracture electron microscopy. FEBS Lett (1994) 356:361-366.
-
(1994)
FEBS Lett
, vol.356
, pp. 361-366
-
-
Sternberg, B.1
Sorgi, F.L.2
Huang, L.3
-
42
-
-
0029857893
-
An electron microscopy study into the mechanism of gene transfer with lipopolyamines
-
Labat-Moleur F, Steffan AM, Brisson C, Perron H, Feugeas O, Furstenberger P, Oberling F, Brambilla E, Behr JP: An electron microscopy study into the mechanism of gene transfer with lipopolyamines. Gene Ther (1996) 3:1010-1017.
-
(1996)
Gene Ther
, vol.3
, pp. 1010-1017
-
-
Labat-Moleur, F.1
Steffan, A.M.2
Brisson, C.3
Perron, H.4
Feugeas, O.5
Furstenberger, P.6
Oberling, F.7
Brambilla, E.8
Behr, J.P.9
-
43
-
-
0030942803
-
Characterization of liposome-mediated gene delivery: Expression, stability, and pharmacokinetics of plasmid DNA
-
Thierry AR, Rabinovich P, Peng B, Mahan LC, Bryant JL, Gallo RC: Characterization of liposome-mediated gene delivery: expression, stability, and pharmacokinetics of plasmid DNA. Gene Ther (1997) 4:226-237.
-
(1997)
Gene Ther
, vol.4
, pp. 226-237
-
-
Thierry, A.R.1
Rabinovich, P.2
Peng, B.3
Mahan, L.C.4
Bryant, J.L.5
Gallo, R.C.6
-
44
-
-
0031013538
-
Loss of binding and entry of liposome-DNA complexes decreases transfection efficiency in differentiated airway epithelial cells
-
Matsui H, Johnson LG, Randell SH, Boucher RC: Loss of binding and entry of liposome-DNA complexes decreases transfection efficiency in differentiated airway epithelial cells. J Biol Chem (1997) 272:1117-1126.
-
(1997)
J Biol Chem
, vol.272
, pp. 1117-1126
-
-
Matsui, H.1
Johnson, L.G.2
Randell, S.H.3
Boucher, R.C.4
-
45
-
-
0030864266
-
A low rate of cell proliferation and reduced DNA uptake limit cationic lipid-mediated gene transfer to primary cultures of ciliated human airway epithelia
-
Fasbender A, Zabner J, Zeiher BG, Welsh MJ: A low rate of cell proliferation and reduced DNA uptake limit cationic lipid-mediated gene transfer to primary cultures of ciliated human airway epithelia. Gene Ther (1997) 4:1173-1180. Demonstration that cell proliferation status may have significant effect on lipid-mediated gene transfer.
-
(1997)
Gene Ther
, vol.4
, pp. 1173-1180
-
-
Fasbender, A.1
Zabner, J.2
Zeiher, B.G.3
Welsh, M.J.4
-
46
-
-
0024150891
-
Structure and biology of proteoglycans
-
Ruoslahti E: Structure and biology of proteoglycans. Annu Rev Cell Biol (1988) 4:229-255.
-
(1988)
Annu Rev Cell Biol
, vol.4
, pp. 229-255
-
-
Ruoslahti, E.1
-
47
-
-
0029981092
-
Evidence for the role of proteoglycans in cation-mediated gene transfer
-
Mislick KA, Baldeschwieler JD: Evidence for the role of proteoglycans in cation-mediated gene transfer. Proc Natl Acad Sci USA (1996) 93:12349-12354. Proteoglycan-negative mutant cell lines and enzymatic inhibition of proteoglycan maturation were used to demonstrate that proteoglycans play a role in poly-L-lysine-mediated gene transfer.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 12349-12354
-
-
Mislick, K.A.1
Baldeschwieler, J.D.2
-
48
-
-
0032475867
-
Proteoglycans mediate cationic liposome-DNA complex-based gene delivery in vitro and in vivo
-
Mounkes LC, Zhong W, Cipes-Palacin G, Heath TD; Debs RJ: Proteoglycans mediate cationic liposome-DNA complex-based gene delivery in vitro and in vivo. J Biol Chem (1998) 273:26164-26170.
-
(1998)
J Biol Chem
, vol.273
, pp. 26164-26170
-
-
Mounkes, L.C.1
Zhong, W.2
Cipes-Palacin, G.3
Heath, T.D.4
Debs, R.J.5
-
49
-
-
0344707080
-
The role of helper lipids in cationic liposome-mediated gene transfer
-
Hui SW, Langner M, Zhao YL, Ross P, Hurley E, Chan K: The role of helper lipids in cationic liposome-mediated gene transfer. Biophys J (1996) 71:590-599.
-
(1996)
Biophys J
, vol.71
, pp. 590-599
-
-
Hui, S.W.1
Langner, M.2
Zhao, Y.L.3
Ross, P.4
Hurley, E.5
Chan, K.6
-
50
-
-
0030833788
-
Contribution of trypsin-sensitive proteins to binding of cationic liposomes to the mouse macrophage-like cell line RAW264.7
-
Arima H, Aramaki Y, Tsuchiya S: Contribution of trypsin-sensitive proteins to binding of cationic liposomes to the mouse macrophage-like cell line RAW264.7. J Pharm Sci (1997) 86:786-790.
-
(1997)
J Pharm Sci
, vol.86
, pp. 786-790
-
-
Arima, H.1
Aramaki, Y.2
Tsuchiya, S.3
-
51
-
-
0032492589
-
Uptake and gene expression of naked plasmid DNA in cultured brain microvessel endothelial cells
-
Nakamura M, Davila-Zavala P, Tokuda H, Takakura Y, Hashida M: Uptake and gene expression of naked plasmid DNA in cultured brain microvessel endothelial cells. Biochem Biophys Res Commun (1998) 245:235-239.
-
(1998)
Biochem Biophys Res Commun
, vol.245
, pp. 235-239
-
-
Nakamura, M.1
Davila-Zavala, P.2
Tokuda, H.3
Takakura, Y.4
Hashida, M.5
-
52
-
-
0029078539
-
Intratracheal gene delivery to the mouse airway: Characterization of plasmid DNA expression and pharmacokinetics
-
Meyer KB, Thompson MM, Levy MY, Barren LG, Szoka FC Jr: Intratracheal gene delivery to the mouse airway: characterization of plasmid DNA expression and pharmacokinetics. Gene Ther (1995) 2:450-460.
-
(1995)
Gene Ther
, vol.2
, pp. 450-460
-
-
Meyer, K.B.1
Thompson, M.M.2
Levy, M.Y.3
Barren, L.G.4
Szoka Jr., F.C.5
-
53
-
-
0029056088
-
Cellular and molecular barriers to gene transfer by a cationic lipid
-
Zabner J, Fasbender AJ, Moninger T, Poellinger KA, Welsh MJ: Cellular and molecular barriers to gene transfer by a cationic lipid. J Biol Chem (1995) 270:18997-19007. Thorough and systematic studies of cellular and molecular factors affecting intracellular cationic lipid complex trafficking.
-
(1995)
J Biol Chem
, vol.270
, pp. 18997-19007
-
-
Zabner, J.1
Fasbender, A.J.2
Moninger, T.3
Poellinger, K.A.4
Welsh, M.J.5
-
54
-
-
0032552426
-
Biodistribution and gene expression of lipid/plasmid complexes after systemic administration
-
Mahato RI, Anwer K, Tagliaferri F, Meaney C, Leonard P, Wadhwa MS. Biodistribution and gene expression of lipid/plasmid complexes after systemic administration. Hum Gene Ther (1998) 9:2083-2099. In vivo analysis of physicochemical properties of cationic lipid complexes. Role of lipid/co-lipid ratios, lipid/plasmid ratios, lipid structure, and lipid complex size are investigated. Effects of polyanionic compounds on gene transfer in vivo.
-
(1998)
Hum Gene Ther
, vol.9
, pp. 2083-2099
-
-
Mahato, R.I.1
Anwer, K.2
Tagliaferri, F.3
Meaney, C.4
Leonard, P.5
Wadhwa, M.S.6
-
55
-
-
0031047951
-
Intracellular distribution of oligonucleotides delivered by cationic liposomes: Light and electron microscopic study
-
Lappalainen K, Miettinen R, Kellokoski J, Jääskeläinen I, Syrjänen S: Intracellular distribution of oligonucleotides delivered by cationic liposomes: light and electron microscopic study. J Histochem Cytochem (1997) 45:265-274.
-
(1997)
J Histochem Cytochem
, vol.45
, pp. 265-274
-
-
Lappalainen, K.1
Miettinen, R.2
Kellokoski, J.3
Jääskeläinen, I.4
Syrjänen, S.5
-
56
-
-
0031559941
-
The role of endosome destabilizing activity in the gene transfer process mediated by cationic lipids
-
El Ouahabi A, Thiry M, Pector V, Fuks R, Ruysschaert JM, Vandenbranden M: The role of endosome destabilizing activity in the gene transfer process mediated by cationic lipids. FEBS Lett (1997) 414:187-192.
-
(1997)
FEBS Lett
, vol.414
, pp. 187-192
-
-
El Ouahabi, A.1
Thiry, M.2
Pector, V.3
Fuks, R.4
Ruysschaert, J.M.5
Vandenbranden, M.6
-
58
-
-
0029240538
-
Phagocytosis
-
Brown EJ: Phagocytosis. Bioessays (1995) 17:109-117.
-
(1995)
Bioessays
, vol.17
, pp. 109-117
-
-
Brown, E.J.1
-
59
-
-
0030876816
-
Analysis of cationic liposome-mediated interactions of plasmid DNA with murine and melanoma cells in vitro
-
Reimer DL, Kong S, Bally MB: Analysis of cationic liposome-mediated interactions of plasmid DNA with murine and melanoma cells in vitro. J Biol Chem (1997) 272:19480-19487.
-
(1997)
J Biol Chem
, vol.272
, pp. 19480-19487
-
-
Reimer, D.L.1
Kong, S.2
Bally, M.B.3
-
60
-
-
0030761195
-
Transfection by cationic liposomes using simultaneous single cell measurements of plasmid delivery and transgene expression
-
Tseng WC, Haselton FR, Giorgio TD: Transfection by cationic liposomes using simultaneous single cell measurements of plasmid delivery and transgene expression. J Biol Chem (1997) 272:25641-25647.
-
(1997)
J Biol Chem
, vol.272
, pp. 25641-25647
-
-
Tseng, W.C.1
Haselton, F.R.2
Giorgio, T.D.3
-
61
-
-
0030458784
-
Efficacy of a peptide-based gene delivery system depends on mitotic activity
-
Wilke M, Fortunati E, van den Broek M, Hoogeveen AT, Scholte BJ: Efficacy of a peptide-based gene delivery system depends on mitotic activity. Gene Ther (1996) 3:1133-1142. Effects of mitosis on plasmid gene transfer using a novel fusion peptide gene delivery system.
-
(1996)
Gene Ther
, vol.3
, pp. 1133-1142
-
-
Wilke, M.1
Fortunati, E.2
Van Den Broek, M.3
Hoogeveen, A.T.4
Scholte, B.J.5
-
62
-
-
0032545793
-
Cationic lipid-mediated gene transfer: Effect of serum on cellular uptake and intracellular fate of lipopotyamine/DNA complexes
-
Escriou V, Ciolina C, Lacroix F, Helbling-Leclerc A, Wils P, Scherman D. Cationic lipid-mediated gene transfer: Effect of serum on cellular uptake and intracellular fate of lipopotyamine/DNA complexes. Biochim Biophys Acta (1998) 1368:276-288.
-
(1998)
Biochim Biophys Acta
, vol.1368
, pp. 276-288
-
-
Escriou, V.1
Ciolina, C.2
Lacroix, F.3
Helbling-Leclerc, A.4
Wils, P.5
Scherman, D.6
-
63
-
-
0032484665
-
Electrostatic and structural properties of complexes involving plasmid DNA and cationic lipids commonly used for gene delivery
-
Zuidam NJ, Barenholz Y: Electrostatic and structural properties of complexes involving plasmid DNA and cationic lipids commonly used for gene delivery. Biochim Biophys Acta Biomembranes (1998) 1368:115-128.
-
(1998)
Biochim Biophys Acta Biomembranes
, vol.1368
, pp. 115-128
-
-
Zuidam, N.J.1
Barenholz, Y.2
-
65
-
-
0029949266
-
Mechanism of DNA release from cationic liposome/DNA complexes used in cell transfection
-
Xu Y, Szoka FC Jr: Mechanism of DNA release from cationic liposome/DNA complexes used in cell transfection. Biochemistry (1996) 35:5616-5623. Proposed mechanism of intracellular endosomal release of cationic lipoplexes. Lateral diffusion of endosomal and complex lipids leads to plasmid escape into the cytoplasm.
-
(1996)
Biochemistry
, vol.35
, pp. 5616-5623
-
-
Xu, Y.1
Szoka Jr., F.C.2
-
66
-
-
0032571392
-
Polyethylenimine but not cationic lipids promotes transgene delivery to the nucleus in mammalian cells
-
Pollard H, Remy J-S, Loussouam G, Demolombe S, Behr JP, Escande D: Polyethylenimine but not cationic lipids promotes transgene delivery to the nucleus in mammalian cells. J Biol Chem (1998) 273:7507-7511. Evidence for active transport of plasmid DNA from the cytoplasm to the nucleus mediated by polyethylenimine, but not cationic lipids.
-
(1998)
J Biol Chem
, vol.273
, pp. 7507-7511
-
-
Pollard, H.1
Remy, J.-S.2
Loussouam, G.3
Demolombe, S.4
Behr, J.P.5
Escande, D.6
-
67
-
-
0026786522
-
Delivery of plasmid DNA into mammalian cell lines using pH-sensitive liposomes: Comparison with cationic liposomes
-
Lengendre JY, Szoka FC Jr: Delivery of plasmid DNA into mammalian cell lines using pH-sensitive liposomes: comparison with cationic liposomes. Pharmacol Res (1992) 9:1235-1242.
-
(1992)
Pharmacol Res
, vol.9
, pp. 1235-1242
-
-
Lengendre, J.Y.1
Szoka Jr., F.C.2
-
68
-
-
0030005461
-
PH-sensitive, cationic liposomes: A new synthetic virus-like vector
-
Budker V, Gurevich V, Hagstrom JE, Bortzov F, Wolff JA: pH-sensitive, cationic liposomes: a new synthetic virus-like vector. Nat Biotechnol (1996) 14:760-764.
-
(1996)
Nat Biotechnol
, vol.14
, pp. 760-764
-
-
Budker, V.1
Gurevich, V.2
Hagstrom, J.E.3
Bortzov, F.4
Wolff, J.A.5
-
69
-
-
0031581171
-
Development and characterization of cationic liposomes conjugated with HVJ (Sendai virus): Reciprocal effect of cationic lipid for in vitro and in vivo gene transfer
-
Saeki Y, Matsumoto N, Nakano Y, Mori M, Awai K, Kaneda Y: Development and characterization of cationic liposomes conjugated with HVJ (Sendai virus): reciprocal effect of cationic lipid for in vitro and in vivo gene transfer. Hum Gene Ther (1997) 8:2133-2141. Effects of lipid/plasmid ratios on in vivo versus in vitro gene transfer.
-
(1997)
Hum Gene Ther
, vol.8
, pp. 2133-2141
-
-
Saeki, Y.1
Matsumoto, N.2
Nakano, Y.3
Mori, M.4
Awai, K.5
Kaneda, Y.6
-
70
-
-
0031872180
-
Characterization of lipid DNA interactions. I. Destabilization of bound lipids and DNA dissociation
-
Harvie P, Wong FM, Bally MB: Characterization of lipid DNA interactions. I. Destabilization of bound lipids and DNA dissociation. Biophys J (1998) 75:1040-1051.
-
(1998)
Biophys J
, vol.75
, pp. 1040-1051
-
-
Harvie, P.1
Wong, F.M.2
Bally, M.B.3
-
71
-
-
0032568628
-
Evidence of interlipidic ion-pairing in anion-induced DNA release from cationic amphiphile-DNA complexes. Mechanistic implications in transfection
-
Bhattacharya S, Mandal SS: Evidence of interlipidic ion-pairing in anion-induced DNA release from cationic amphiphile-DNA complexes. Mechanistic implications in transfection. Biochemistry (1998) 37:7764-7777. Mechanisms of plasmid DNA uncoating and implications for gene transfer.
-
(1998)
Biochemistry
, vol.37
, pp. 7764-7777
-
-
Bhattacharya, S.1
Mandal, S.S.2
-
72
-
-
0031983912
-
Inclusion of cholesterol in DOTAP transfection complexes increases the delivery of DNA to cells in vitro in the presence of serum
-
Crook K, Stevenson BJ, Dubouchet M, Porteous DJ: Inclusion of cholesterol in DOTAP transfection complexes increases the delivery of DNA to cells in vitro in the presence of serum. Gene Ther (1998) 5:137-143.
-
(1998)
Gene Ther
, vol.5
, pp. 137-143
-
-
Crook, K.1
Stevenson, B.J.2
Dubouchet, M.3
Porteous, D.J.4
-
73
-
-
0032536438
-
Effect of serum components on the physico-chemical properties of cationic lipid/oligonucleotide complexes and on their interactions with cells
-
Zelphati O, Uyechi LS, Barron LG, Szoka FC Jr: Effect of serum components on the physico-chemical properties of cationic lipid/oligonucleotide complexes and on their interactions with cells. Biochim Biophys Acta (1998) 1390:119-133.
-
(1998)
Biochim Biophys Acta
, vol.1390
, pp. 119-133
-
-
Zelphati, O.1
Uyechi, L.S.2
Barron, L.G.3
Szoka Jr., F.C.4
-
74
-
-
0019191911
-
High efficiency transformation by direct microinjection of DNA into cultured mammalian cells
-
Capecchi MR: High efficiency transformation by direct microinjection of DNA into cultured mammalian cells. Cell (1980) 22:479-488. Initial report to indicate that plasmid DNA, microinjected into the cytoplasm, is not efficiently transported into the nucleus.
-
(1980)
Cell
, vol.22
, pp. 479-488
-
-
Capecchi, M.R.1
-
75
-
-
0031079644
-
Import of plasmid DNA into the nucleus is sequence specific
-
Dean DA: Import of plasmid DNA into the nucleus is sequence specific. Exp Cell Res (1997) 230:293-302. Identification of viral gene sequences, incorporated into plasmid DNA, which may promote active transport into the cell nucleus.
-
(1997)
Exp Cell Res
, vol.230
, pp. 293-302
-
-
Dean, D.A.1
-
76
-
-
0020442374
-
Liposome-mediated DNA gene transfer in eukaryotic cells. Dependence of the transfer efficiency upon the type of liposomes used and the host cell cycle stage
-
Nicolau C, Sene C: Liposome-mediated DNA gene transfer in eukaryotic cells. Dependence of the transfer efficiency upon the type of liposomes used and the host cell cycle stage. Biochim Biophys Acta (1982) 721:185-190.
-
(1982)
Biochim Biophys Acta
, vol.721
, pp. 185-190
-
-
Nicolau, C.1
Sene, C.2
-
77
-
-
0022000581
-
Enhancement of DNA-mediated gene transfer by high-M, carrier DNA in synchronized CV-1 cells
-
Strain AJ, Wallace WAH, Wyllie AH: Enhancement of DNA-mediated gene transfer by high-M, carrier DNA in synchronized CV-1 cells. Biochem J (1985) 225:529-533.
-
(1985)
Biochem J
, vol.225
, pp. 529-533
-
-
Strain, A.J.1
Wallace, W.A.H.2
Wyllie, A.H.3
-
78
-
-
0032551589
-
Efficiency of cationic lipid-mediated transfection of polarized and differentiated airway epithelial cells in vitro and in vivo
-
Jiang C, O'Conner S, Fang SI Wang KX, Marshall J, Williams JL. Efficiency of cationic lipid-mediated transfection of polarized and differentiated airway epithelial cells in vitro and in vivo. Human Gene Ther (1998) 9:1531-1542. Description of potential barriers to intrapulmonary lipid-mediated gene transfer cell polarity, differentiation and proliferate state. Evidence of deferential requirement of cationic lipid for plasmid gene transfer depending on the route of administration.
-
(1998)
Human Gene Ther
, vol.9
, pp. 1531-1542
-
-
Jiang, C.1
O'Conner, S.2
Fang, S.I.3
Wang, K.X.4
Marshall, J.5
Williams, J.L.6
-
79
-
-
0031056543
-
Gene transfer by guanidinium-cholesterol cationic lipids into airway epithelial cells in vitro and in vivo
-
Oudrhiri N, Vigneron JP, Peuchmaur M, LeClerc T, Lehn JM, Lehn P: Gene transfer by guanidinium-cholesterol cationic lipids into airway epithelial cells in vitro and in vivo. Proc Natl Acad Sci USA (1997) 94:1651-1656.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 1651-1656
-
-
Oudrhiri, N.1
Vigneron, J.P.2
Peuchmaur, M.3
LeClerc, T.4
Lehn, J.M.5
Lehn, P.6
-
80
-
-
0026710580
-
Increased efficiency of gene transfection in primary cultures of adult rat hepatocytes stimulated to proliferate: A comparative study using the lipofection and calcium phosphate precipitate methods
-
Somasundaram C, Toumier I, Feldmann G, Bemuau D: Increased efficiency of gene transfection in primary cultures of adult rat hepatocytes stimulated to proliferate: a comparative study using the lipofection and calcium phosphate precipitate methods. Cell Biol Int Rep (1992) 16:653-662.
-
(1992)
Cell Biol Int Rep
, vol.16
, pp. 653-662
-
-
Somasundaram, C.1
Toumier, I.2
Feldmann, G.3
Bemuau, D.4
-
81
-
-
0031976511
-
Nuclear localization signal peptides enhance cationic liposome-mediated gene therapy
-
Aronsohn AI, Hughes JA: Nuclear localization signal peptides enhance cationic liposome-mediated gene therapy. J Drug Target (1998) 5:163-169.
-
(1998)
J Drug Target
, vol.5
, pp. 163-169
-
-
Aronsohn, A.I.1
Hughes, J.A.2
-
82
-
-
0031934035
-
Gene transduction for disseminated intraperitoneal tumor using cationic liposomes containing non-histone chromatin proteins: Cationic liposomal gene therapy of carcinomatosa
-
Namiki Y, Takahashi T, Ohno T: Gene transduction for disseminated intraperitoneal tumor using cationic liposomes containing non-histone chromatin proteins: cationic liposomal gene therapy of carcinomatosa. Gene Ther (1998) 5:240-246.
-
(1998)
Gene Ther
, vol.5
, pp. 240-246
-
-
Namiki, Y.1
Takahashi, T.2
Ohno, T.3
-
83
-
-
0031717882
-
Stable and monodispersed lipoplex formulations for gene delivery
-
Zelphati O, Nguyeri C, Ferrari M, Felgner J, Tsai Y, Felgner PL. Stable and monodispersed lipoplex formulations for gene delivery. Gene Ther (1998) 5:1272-1282. Studies toward the development of systematic methods to prepare and define lipoplex formulations.
-
(1998)
Gene Ther
, vol.5
, pp. 1272-1282
-
-
Zelphati, O.1
Nguyeri, C.2
Ferrari, M.3
Felgner, J.4
Tsai, Y.5
Felgner, P.L.6
-
84
-
-
0030760143
-
Improved DNA: Liposome complexes for increased systemic delivery and gene expression
-
Templeton NS, Lasic DD, Frederik PM, Strey HH, Roberts DD, Pavlakis GN: Improved DNA: liposome complexes for increased systemic delivery and gene expression. Nat Biotechnol (1997) 15:647-652.
-
(1997)
Nat Biotechnol
, vol.15
, pp. 647-652
-
-
Templeton, N.S.1
Lasic, D.D.2
Frederik, P.M.3
Strey, H.H.4
Roberts, D.D.5
Pavlakis, G.N.6
-
85
-
-
0031049765
-
Factors influencing the efficiency of cationic liposome-mediated intravenous gene delivery
-
Liu Y, Mounkes LC, Liggitt HD, Brown CS, Solodin I, Heath TD, Debs RJ: Factors influencing the efficiency of cationic liposome-mediated intravenous gene delivery. Nat Biotechnol (1997) 15:167-173.
-
(1997)
Nat Biotechnol
, vol.15
, pp. 167-173
-
-
Liu, Y.1
Mounkes, L.C.2
Liggitt, H.D.3
Brown, C.S.4
Solodin, I.5
Heath, T.D.6
Debs, R.J.7
-
86
-
-
25544447713
-
Improved cationic lipid-mediated transgene expression following direct intra-tumoral injection in human tumor-bearing SCID mice using increased lipid:DNA ratios
-
Clark PR, Stopeck AT, Parker SE, Norman J, Hersh EM. Improved cationic lipid-mediated transgene expression following direct intra-tumoral injection in human tumor-bearing SCID mice using increased lipid:DNA ratios. Cancer Gene Ther (1996) 3:S17.
-
(1996)
Cancer Gene Ther
, vol.3
-
-
Clark, P.R.1
Stopeck, A.T.2
Parker, S.E.3
Norman, J.4
Hersh, E.M.5
-
87
-
-
0026459987
-
Aerosol gene delivery in vivo
-
Stribling R, Bumette E, Liggitt D, Gaensler K, Debs R: Aerosol gene delivery in vivo. Proc Natl Acad Sci USA (1992) 89:11277-11281.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 11277-11281
-
-
Stribling, R.1
Bumette, E.2
Liggitt, D.3
Gaensler, K.4
Debs, R.5
-
88
-
-
6844258214
-
Comparison between intratracheal and intravenous administration of liposome-DNA complexes for cystic fibrosis lung gene therapy
-
Griesenbach U, Chonn A, Cassady R, Hannam V, Ackerley C, Post M, Tanswell AK, Olek K, Obrodovich H, Tsui LC: Comparison between intratracheal and intravenous administration of liposome-DNA complexes for cystic fibrosis lung gene therapy. Gene Ther (1998) 5:181-188.
-
(1998)
Gene Ther
, vol.5
, pp. 181-188
-
-
Griesenbach, U.1
Chonn, A.2
Cassady, R.3
Hannam, V.4
Ackerley, C.5
Post, M.6
Tanswell, A.K.7
Olek, K.8
Obrodovich, H.9
Tsui, L.C.10
-
89
-
-
17144451211
-
Plasmid DNA gene therapy: Studies with the human interleukin-2 gene in tumor cells in vitro and the murine B16 melanoma model in vivo
-
Parker SE, Khatibi S, Margalith M, Anderson D, Yankauckas M, Gromkowski SH, Latimer T, Lew D, Marquet M, Manthorpe M, Hobart P, Hersh E, Stopeck AT, Norman J: Plasmid DNA gene therapy: studies with the human interleukin-2 gene in tumor cells in vitro and the murine B16 melanoma model in vivo. Cancer Gene Ther (1996) 3:175-185. Description of the potential non-specific antitumor effects of intratumoral delivery of cationic lipid-DNA complexes.
-
(1996)
Cancer Gene Ther
, vol.3
, pp. 175-185
-
-
Parker, S.E.1
Khatibi, S.2
Margalith, M.3
Anderson, D.4
Yankauckas, M.5
Gromkowski, S.H.6
Latimer, T.7
Lew, D.8
Marquet, M.9
Manthorpe, M.10
Hobart, P.11
Hersh, E.12
Stopeck, A.T.13
Norman, J.14
-
90
-
-
0030888569
-
Direct intratumoral gene transfer of the herpes simplex virus thymidine kinase gene with DNA-liposome complexes: Growth inhibition of tumors and lack of localization in normal tissues
-
Takakuwa K, Fujita K, Kikuchi A, Sugaya S, Yahata T, Aida H, Kurabayashi T, Hasegawa I, Tanaka K: Direct intratumoral gene transfer of the herpes simplex virus thymidine kinase gene with DNA-liposome complexes: growth inhibition of tumors and lack of localization in normal tissues. Jpn J Cancer Res (1997) 88:166-175.
-
(1997)
Jpn J Cancer Res
, vol.88
, pp. 166-175
-
-
Takakuwa, K.1
Fujita, K.2
Kikuchi, A.3
Sugaya, S.4
Yahata, T.5
Aida, H.6
Kurabayashi, T.7
Hasegawa, I.8
Tanaka, K.9
-
91
-
-
0029585521
-
Lipospermine-based gene transfer into the newborn mouse brain is optimized by a low lipospermine/DNA charge ratio
-
Schwartz B, Benoist C, Abdallah B, Scherman D, Behr JP, Demeneix BA: Lipospermine-based gene transfer into the newborn mouse brain is optimized by a low lipospermine/DNA charge ratio. Hum Gene Ther (1995) 6:1515-1524.
-
(1995)
Hum Gene Ther
, vol.6
, pp. 1515-1524
-
-
Schwartz, B.1
Benoist, C.2
Abdallah, B.3
Scherman, D.4
Behr, J.P.5
Demeneix, B.A.6
-
92
-
-
0030759153
-
Comparison of DNA-lipid complexes and DNA alone for gene transfer to cystic fibrosis airway epithelia in vivo
-
Zabner J, Cheng SH, Meeker D, Launspach J, Balfour R, Perricone MA, Morris JE, Marshall J, Fasbender A, Smith AE, Welsh MJ: Comparison of DNA-lipid complexes and DNA alone for gene transfer to cystic fibrosis airway epithelia in vivo. J Clin Invest (1997) 100:1529-1537.
-
(1997)
J Clin Invest
, vol.100
, pp. 1529-1537
-
-
Zabner, J.1
Cheng, S.H.2
Meeker, D.3
Launspach, J.4
Balfour, R.5
Perricone, M.A.6
Morris, J.E.7
Marshall, J.8
Fasbender, A.9
Smith, A.E.10
Welsh, M.J.11
-
93
-
-
0030957838
-
Surfactant inhibits cationic liposome-mediated gene transfer
-
Tsan MF, Tsan GL, White JE: Surfactant inhibits cationic liposome-mediated gene transfer. Hum Gene Ther (1997) 8:817-825.
-
(1997)
Hum Gene Ther
, vol.8
, pp. 817-825
-
-
Tsan, M.F.1
Tsan, G.L.2
White, J.E.3
-
94
-
-
0030793192
-
Intratumoral pharmacokinetics and in vivo gene expression of naked plasmid DNA and its cationic liposome complexes after direct gene transfer
-
Nomura T, Nakajima S, Kawabata K, Yamashita F, Takakura Y, Hashida M: Intratumoral pharmacokinetics and in vivo gene expression of naked plasmid DNA and its cationic liposome complexes after direct gene transfer. Cancer Res (1997) 57:2681-2686. Pharmacokinetic biodistribution of plasmid DNA and lipid complexed plasmid DNA following intratumoral injection.
-
(1997)
Cancer Res
, vol.57
, pp. 2681-2686
-
-
Nomura, T.1
Nakajima, S.2
Kawabata, K.3
Yamashita, F.4
Takakura, Y.5
Hashida, M.6
-
95
-
-
0029891426
-
Direct gene transfer to mouse melanoma by intratumor injection of free DNA
-
Yang JP, Huang L: Direct gene transfer to mouse melanoma by intratumor injection of free DNA. Gene Ther (1996) 3:542-548. Systematic study of the factors affecting intratumoral gene transfer of naked DNA. Evidence for inhibitory activity of cationic lipids in tumor tissue.
-
(1996)
Gene Ther
, vol.3
, pp. 542-548
-
-
Yang, J.P.1
Huang, L.2
-
96
-
-
0029898019
-
Long-term expression of the human α1-antitrypsin gene in mice employing anionic and cationic liposome vectors
-
Crespo J, Blaya C, Crespo A, Aliño SF: Long-term expression of the human α1-antitrypsin gene in mice employing anionic and cationic liposome vectors. Biochem Pharmacol (1996) 51:1309-1314.
-
(1996)
Biochem Pharmacol
, vol.51
, pp. 1309-1314
-
-
Crespo, J.1
Blaya, C.2
Crespo, A.3
Aliño, S.F.4
-
97
-
-
0030759050
-
Overcoming the inhibitory effect of serum on lipofection by increasing the charge ratio of cationic liposome to DNA
-
Yang JP, Huang L: Overcoming the inhibitory effect of serum on lipofection by increasing the charge ratio of cationic liposome to DNA. Gene Ther (1997) 4:950-960
-
(1997)
Gene Ther
, vol.4
, pp. 950-960
-
-
Yang, J.P.1
Huang, L.2
-
98
-
-
6844266288
-
The effect of mucolytic agents on gene transfer across a CF sputum barrier in vitro
-
Stem M, Caplen NJ, Browning JE, Griesenbach U, Sorgi F, Huang L, Gruenert DC, Marriot C, Crystal RG, Geddes DM, Alton EW: The effect of mucolytic agents on gene transfer across a CF sputum barrier in vitro. Gene Ther (1998) 5:91-98.
-
(1998)
Gene Ther
, vol.5
, pp. 91-98
-
-
Stem, M.1
Caplen, N.J.2
Browning, J.E.3
Griesenbach, U.4
Sorgi, F.5
Huang, L.6
Gruenert, D.C.7
Marriot, C.8
Crystal, R.G.9
Geddes, D.M.10
Alton, E.W.11
-
99
-
-
0030974582
-
Pulmonary surfactant inhibits cationic liposome-mediated gene delivery to respiratory epithelial cells in vitro
-
Duncan JE, Whitsett JA, Horowitz AD: Pulmonary surfactant inhibits cationic liposome-mediated gene delivery to respiratory epithelial cells in vitro. Hum Gene Ther (1997) 8:431-438.
-
(1997)
Hum Gene Ther
, vol.8
, pp. 431-438
-
-
Duncan, J.E.1
Whitsett, J.A.2
Horowitz, A.D.3
-
100
-
-
0026669404
-
Cationic lipid-mediated transaction of liver cells in primary culture
-
Jamagin WR, Debs RJ, Wang SS, Bissell DM: Cationic lipid-mediated transaction of liver cells in primary culture. Nucleic Acids Res (1992) 20:4205-4211.
-
(1992)
Nucleic Acids Res
, vol.20
, pp. 4205-4211
-
-
Jamagin, W.R.1
Debs, R.J.2
Wang, S.S.3
Bissell, D.M.4
-
101
-
-
0029793791
-
Effect of amniotic fluid on cationic lipid-mediated transfection and retroviral infection
-
Douar AM, Themis M, Sandig V, Friedmann T, Coutelle C: Effect of amniotic fluid on cationic lipid-mediated transfection and retroviral infection. Gene Ther (1996) 3:789-796.
-
(1996)
Gene Ther
, vol.3
, pp. 789-796
-
-
Douar, A.M.1
Themis, M.2
Sandig, V.3
Friedmann, T.4
Coutelle, C.5
-
102
-
-
0031889196
-
Effect of particle size and charge on the disposition of lipid carriers after intratumoral injection into tissue-isolated tumors
-
Nomura T, Koreeda N, Yamashita F, Takakura Y, Hashida M: Effect of particle size and charge on the disposition of lipid carriers after intratumoral injection into tissue-isolated tumors. Pharm Res (1998) 15:128-132. Evidence concerning the effects of particle size and charge of liposomes on their biodistribution within tumor tissue. Implications for intratumoral cationic lipoplex-mediated gene transfer.
-
(1998)
Pharm Res
, vol.15
, pp. 128-132
-
-
Nomura, T.1
Koreeda, N.2
Yamashita, F.3
Takakura, Y.4
Hashida, M.5
-
103
-
-
0030668116
-
Characterization of cationic liposome-mediated gene transfer in vivo by intravenous administration
-
Song YK, Liu F, Chu S, Liu D: Characterization of cationic liposome-mediated gene transfer in vivo by intravenous administration. Hum Gene Ther (1997) 8:1585-1594.
-
(1997)
Hum Gene Ther
, vol.8
, pp. 1585-1594
-
-
Song, Y.K.1
Liu, F.2
Chu, S.3
Liu, D.4
-
104
-
-
0032562981
-
Free liposomes enhance the transfection activity of DNA/lipid complexes in vivo by intravenous administration
-
Song YK, Liu D: Free liposomes enhance the transfection activity of DNA/lipid complexes in vivo by intravenous administration. Biochim Biophys Acta (1998) 1372:141-150.
-
(1998)
Biochim Biophys Acta
, vol.1372
, pp. 141-150
-
-
Song, Y.K.1
Liu, D.2
-
105
-
-
17344368550
-
Effects of complement depletion on the pharmacokinetics and gene delivery mediated by cationic lipid-DNA complexes
-
Barron LG, Meyer KB, Szoka FC Jr: Effects of complement depletion on the pharmacokinetics and gene delivery mediated by cationic lipid-DNA complexes. Hum Gene Ther (1998) 9:315-323.
-
(1998)
Hum Gene Ther
, vol.9
, pp. 315-323
-
-
Barron, L.G.1
Meyer, K.B.2
Szoka Jr., F.C.3
-
106
-
-
0030008620
-
33P]DNa following intravenous administration of DNA/cationic lipid complexes in mice: Use of a novel radionuclide approach
-
33P]DNA following intravenous administration of DNA/cationic lipid complexes in mice: use of a novel radionuclide approach. J Pharm Sci (1996) 85:612-618.
-
(1996)
J Pharm Sci
, vol.85
, pp. 612-618
-
-
Osaka, G.1
Carey, K.2
Cuthbertson, A.3
Godowski, P.4
Patapoff, T.5
Ryan, A.6
Gadek, T.7
Mordenti, J.8
-
107
-
-
0029967080
-
Fate of cationic liposomes and their complex with oligonucleotide in vivo
-
Utzinger DC, Brown JM, Wala I, Kaufman SA Van GY, Farrell CL, Collins D: Fate of cationic liposomes and their complex with oligonucleotide in vivo. Biochim Biophys Acta (1996) 1281:139-149.
-
(1996)
Biochim Biophys Acta
, vol.1281
, pp. 139-149
-
-
Utzinger, D.C.1
Brown, J.M.2
Wala, I.3
Kaufman, S.A.4
Van, G.Y.5
Farrell, C.L.6
Collins, D.7
-
108
-
-
4244142621
-
Organ-specific endothelial cell uptake of cationic liposome-DNA complexes in mice
-
McLean JW, Fox EA, Baluk P, Bolton PB, Haskell A, Pearlman R, Thurston G, Umemoto EY, McDonald DM: Organ-specific endothelial cell uptake of cationic liposome-DNA complexes in mice. Am J Physiol (1997) 273:H387-H404.
-
(1997)
Am J Physiol
, vol.273
-
-
McLean, J.W.1
Fox, E.A.2
Baluk, P.3
Bolton, P.B.4
Haskell, A.5
Pearlman, R.6
Thurston, G.7
Umemoto, E.Y.8
McDonald, D.M.9
-
109
-
-
0030942102
-
Tissue distribution of the cytofectin component of a plasmid-DNA/cationic lipid complex following intravenous administration in mice
-
Parker SE, Ducharme S, Norman J, Wheeler CJ: Tissue distribution of the cytofectin component of a plasmid-DNA/cationic lipid complex following intravenous administration in mice. Hum Gene Ther (1997) 8:393-401.
-
(1997)
Hum Gene Ther
, vol.8
, pp. 393-401
-
-
Parker, S.E.1
Ducharme, S.2
Norman, J.3
Wheeler, C.J.4
-
110
-
-
0030950392
-
In vivo gene transfer by intravenous administration of stable cationic lipid/DNA complexes
-
Hofland HE, Nagy D, Liu JJ, Spratt K, Lee YL, Danos O, Sullivan SM: In vivo gene transfer by intravenous administration of stable cationic lipid/DNA complexes. Pharm Res (1997) 14:742-749.
-
(1997)
Pharm Res
, vol.14
, pp. 742-749
-
-
Hofland, H.E.1
Nagy, D.2
Liu, J.J.3
Spratt, K.4
Lee, Y.L.5
Danos, O.6
Sullivan, S.M.7
-
111
-
-
0029983435
-
Evaluation and optimization of different cationic liposome formulations for in vivo gene transfer
-
Egilmez NK, Iwanuma Y, Bankert RB: Evaluation and optimization of different cationic liposome formulations for in vivo gene transfer. Biochem Biophys Res Commun (1996) 5:169-173. Comparison of a panel of cationic lipids and their activity for intratumoral gene transfer in an in vivo setting.
-
(1996)
Biochem Biophys Res Commun
, vol.5
, pp. 169-173
-
-
Egilmez, N.K.1
Iwanuma, Y.2
Bankert, R.B.3
-
112
-
-
0027280569
-
Immunotherapy of malignancy by in vivo gene transfer into tumors
-
Plautz GE, Yang ZY, Wu BY, Gao X, Huang L, Nabel GJ: Immunotherapy of malignancy by in vivo gene transfer into tumors. Proc Natl Acad Sci USA (1993) 90:4645-4649. An early study employing the use of cationic lipids to achieve therapeutic in vivo gene transfer. The authors hypothesize that the intratumoral expression of an allogeneic MHC antigen resulted in a cytokine cascade which triggered the development of specific immunity to intrinsic tumor associated antigens.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 4645-4649
-
-
Plautz, G.E.1
Yang, Z.Y.2
Wu, B.Y.3
Gao, X.4
Huang, L.5
Nabel, G.J.6
-
114
-
-
0029737009
-
In vivo cytokine gene therapy of human tumor xenografts in SCID mice by liposome-mediated DNA delivery
-
Egilmez NK, Cuenca R, Yokota SJ, Sorgi F, Bankert RB: In vivo cytokine gene therapy of human tumor xenografts in SCID mice by liposome-mediated DNA delivery. Gene Ther (1996) 3:607-614.
-
(1996)
Gene Ther
, vol.3
, pp. 607-614
-
-
Egilmez, N.K.1
Cuenca, R.2
Yokota, S.J.3
Sorgi, F.4
Bankert, R.B.5
-
115
-
-
2442744744
-
Development of an intra-tumoral injection assay system in SCID mice: Serum IL-2 and plasmid efflux detected following intra-tumoral injection of naked plasmid DNA
-
Clark PR, Ferrari M, Felgner PL, Hersh EM: Development of an intra-tumoral injection assay system in SCID mice: Serum IL-2 and plasmid efflux detected following intra-tumoral injection of naked plasmid DNA. Cancer Gene Ther (1997) 4:554.
-
(1997)
Cancer Gene Ther
, vol.4
, pp. 554
-
-
Clark, P.R.1
Ferrari, M.2
Felgner, P.L.3
Hersh, E.M.4
-
116
-
-
0028896863
-
Cationic lipids for reporter gene and CFTR transfer to rat pulmonary epithelium
-
Logan JJ, Bebok Z, Walker LC, Peng S, Felgner PL, Siegal GP, Frizzell RA, Dong J, Howard M, Matalon S, Lindsey JR, DuVall M, Srscher EJ: Cationic lipids for reporter gene and CFTR transfer to rat pulmonary epithelium. Gene Ther (1995) 2:38-49.
-
(1995)
Gene Ther
, vol.2
, pp. 38-49
-
-
Logan, J.J.1
Bebok, Z.2
Walker, L.C.3
Peng, S.4
Felgner, P.L.5
Siegal, G.P.6
Frizzell, R.A.7
Dong, J.8
Howard, M.9
Matalon, S.10
Lindsey, J.R.11
DuVall, M.12
Srscher, E.J.13
-
118
-
-
16044364926
-
A novel cationic lipid greatly enhances plasmid DNA delivery and expression in mouse lung
-
Wheeler CJ, Felgner PL, Tsai YJ, Marshall J, Sukku L, Doh SG, Hartikka J, Nietupski J, Manthorpe M, Nichols M, Plewe M, Uang X, Norman J, Smith A, Cheng SH: A novel cationic lipid greatly enhances plasmid DNA delivery and expression in mouse lung. Proc Natl Acad Sci USA (1996) 93:11454-11459.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 11454-11459
-
-
Wheeler, C.J.1
Felgner, P.L.2
Tsai, Y.J.3
Marshall, J.4
Sukku, L.5
Doh, S.G.6
Hartikka, J.7
Nietupski, J.8
Manthorpe, M.9
Nichols, M.10
Plewe, M.11
Uang, X.12
Norman, J.13
Smith, A.14
Cheng, S.H.15
-
119
-
-
19244363903
-
Detailed analysis of structures and formulations of cationic lipids for efficient gene transfer to the lung
-
Lee ER, Marshall J, Siegel CS, Jiang C, Yew NS, Nichols MR, Nietupski JB, Ziegler RJ, Lane MB, Wang KX, Wan NC, Scheule RK, Harris DJ, Smith AE Cheng SH: Detailed analysis of structures and formulations of cationic lipids for efficient gene transfer to the lung. Hum Gene Ther (1996) 7:1701-1717.
-
(1996)
Hum Gene Ther
, vol.7
, pp. 1701-1717
-
-
Lee, E.R.1
Marshall, J.2
Siegel, C.S.3
Jiang, C.4
Yew, N.S.5
Nichols, M.R.6
Nietupski, J.B.7
Ziegler, R.J.8
Lane, M.B.9
Wang, K.X.10
Wan, N.C.11
Scheule, R.K.12
Harris, D.J.13
Smith, A.E.14
Cheng, S.H.15
-
120
-
-
0026625385
-
Expression of the human cystic fibrosis transmembrane conductance regulator gene in the mouse lung after in vivo intratracheal plasmid-mediated gene transfer
-
Yoshimura K, Rosenfeld MA, Nakamura H, Scherer EM, Pavirani A, Lecocq JP, Crystal RG: Expression of the human cystic fibrosis transmembrane conductance regulator gene in the mouse lung after in vivo intratracheal plasmid-mediated gene transfer. Nucleic Acids Res (1992) 20:3233-3240.
-
(1992)
Nucleic Acids Res
, vol.20
, pp. 3233-3240
-
-
Yoshimura, K.1
Rosenfeld, M.A.2
Nakamura, H.3
Scherer, E.M.4
Pavirani, A.5
Lecocq, J.P.6
Crystal, R.G.7
-
121
-
-
16944361840
-
A concentrated and stable aerosol formulation of cationic lipid:DNA complexes giving high-level gene expression in mouse lung
-
Eastman SJ, Lukason MJ, Tousignant JD, Murray H, Lane MD, St George JA, Akita GY, Cherry M, Cheng SH, Scheule RK: A concentrated and stable aerosol formulation of cationic lipid:DNA complexes giving high-level gene expression in mouse lung. Hum Gene Ther (1997) 8:765-773.
-
(1997)
Hum Gene Ther
, vol.8
, pp. 765-773
-
-
Eastman, S.J.1
Lukason, M.J.2
Tousignant, J.D.3
Murray, H.4
Lane, M.D.5
St George, J.A.6
Akita, G.Y.7
Cherry, M.8
Cheng, S.H.9
Scheule, R.K.10
-
122
-
-
0030754344
-
Optimization of formulations and conditions for the aerosol delivery of functional cationic lipid:DNA complexes
-
Eastman SJ, Tousignant JD, Lukason MJ, Murray H, Siegel CS, Constantino P, Harris DJ, Cheng SH, Scheule RK: Optimization of formulations and conditions for the aerosol delivery of functional cationic lipid:DNA complexes. Hum Gene Ther (1997) 8:313-322.
-
(1997)
Hum Gene Ther
, vol.8
, pp. 313-322
-
-
Eastman, S.J.1
Tousignant, J.D.2
Lukason, M.J.3
Murray, H.4
Siegel, C.S.5
Constantino, P.6
Harris, D.J.7
Cheng, S.H.8
Scheule, R.K.9
-
123
-
-
16944364834
-
Basis of pulmonary toxicity associated with cationic lipid-mediated gene transfer to the mammalian lung
-
Scheule RK, St George JA, Bagley RG, Marshall J, Kaplan JM, Akita GY, Wang KX, Lee ER, Harris DJ, Jiang C, Yew NS, Smith AE, Cheng SH: Basis of pulmonary toxicity associated with cationic lipid-mediated gene transfer to the mammalian lung. Hum Gene Ther (1997) 8:689-707. Characterization of pulmonary toxicity due to cationic lipids, plasmid DNA and cationic lipid/DNA complexes. Pharmacological (sodium butyrate) enhancement of gene transfer in the lung.
-
(1997)
Hum Gene Ther
, vol.8
, pp. 689-707
-
-
Scheule, R.K.1
St George, J.A.2
Bagley, R.G.3
Marshall, J.4
Kaplan, J.M.5
Akita, G.Y.6
Wang, K.X.7
Lee, E.R.8
Harris, D.J.9
Jiang, C.10
Yew, N.S.11
Smith, A.E.12
Cheng, S.H.13
-
125
-
-
0028876942
-
Inhibition of human ovarian carcinoma cell proliferation by liposome-plasmid DNA complex
-
Hofland H, Huang L: Inhibition of human ovarian carcinoma cell proliferation by liposome-plasmid DNA complex. Biochem Biophys Res Comm (1995) 207:492-496.
-
(1995)
Biochem Biophys Res Comm
, vol.207
, pp. 492-496
-
-
Hofland, H.1
Huang, L.2
-
126
-
-
0025356901
-
Interactions of mammalian cells with lipid dispersions containing novel metabolizable cationic amphiphiles
-
Leventis R, Silvius JR: Interactions of mammalian cells with lipid dispersions containing novel metabolizable cationic amphiphiles. Bochim Biophys Acta (1990) 1023:124-132.
-
(1990)
Bochim Biophys Acta
, vol.1023
, pp. 124-132
-
-
Leventis, R.1
Silvius, J.R.2
-
127
-
-
0030930054
-
Anti-inflammatory activity of cationic lipids
-
Filion MC, Phillips NC: Anti-inflammatory activity of cationic lipids. Br J Pharmacol (1997) 122:551-557. Differential effects of cationic lipids on intacellular protein kinases. Mechanism of action for lipid-mediated anti-inflammatory activity in macrophages.
-
(1997)
Br J Pharmacol
, vol.122
, pp. 551-557
-
-
Filion, M.C.1
Phillips, N.C.2
-
128
-
-
0031698256
-
Induction of interferon synthesis and activation of interferon stimulated gene by liposomal transfection reagents
-
Li X-L, Boyanapalli M, Weihua X, Walker NJ, Gruenert DC, Nantz MH: Induction of interferon synthesis and activation of interferon stimulated gene by liposomal transfection reagents. J Interferon Cytokine Res (1998) 18:947-952.
-
(1998)
J Interferon Cytokine Res
, vol.18
, pp. 947-952
-
-
Li, X.-L.1
Boyanapalli, M.2
Weihua, X.3
Walker, N.J.4
Gruenert, D.C.5
Nantz, M.H.6
-
129
-
-
0032485880
-
A novel tetraester construct that reduces cationic lipid- Associated cytotoxlcity. Implications for the onset of cytotoxicity
-
Aberle AM, Tablin F, Zhu J, Walker NJ, Gruenert DC, Nantz MH: A novel tetraester construct that reduces cationic lipid-associated cytotoxlcity. Implications for the onset of cytotoxicity. Biochemistry (1998) 37:6533-6540.
-
(1998)
Biochemistry
, vol.37
, pp. 6533-6540
-
-
Aberle, A.M.1
Tablin, F.2
Zhu, J.3
Walker, N.J.4
Gruenert, D.C.5
Nantz, M.H.6
-
130
-
-
0025934603
-
Interaction of positively- Charged liposomes with blood: Implications for their application in vivo
-
Senior JH, Trimble KR, Maskiewicz R: Interaction of positively-charged liposomes with blood: Implications for their application in vivo. Biochim Biophys Acta (1991) 1070:173-179.
-
(1991)
Biochim Biophys Acta
, vol.1070
, pp. 173-179
-
-
Senior, J.H.1
Trimble, K.R.2
Maskiewicz, R.3
-
131
-
-
0030669761
-
Physicochemical properties and in vitro toxicity of cationic liposome cDNA complexes
-
Schreier H, Gagne L, Bock T, Erdos GW, Druzgala P, Conary JT, Müller BW: Physicochemical properties and in vitro toxicity of cationic liposome cDNA complexes. Pharm Acta Helv (1997) 72:215-223.
-
(1997)
Pharm Acta Helv
, vol.72
, pp. 215-223
-
-
Schreier, H.1
Gagne, L.2
Bock, T.3
Erdos, G.W.4
Druzgala, P.5
Conary, J.T.6
Müller, B.W.7
-
132
-
-
0029789793
-
Activation of the complement system by synthetic DNa complexes: A potential barrier for intravenous gene delivery
-
Plank C, Mechtler K, Szoka FC Jr, Wagner E: Activation of the complement system by synthetic DNA complexes: a potential barrier for intravenous gene delivery. Hum Gene Ther (1996) 7:1437-1446.
-
(1996)
Hum Gene Ther
, vol.7
, pp. 1437-1446
-
-
Plank, C.1
Mechtler, K.2
Szoka Jr., F.C.3
Wagner, E.4
-
134
-
-
0031688612
-
Inflammatory responses following direct injection of plasmid DNA into skeletal muscle
-
McMahon JM, Wells KE, Bamfo JE, Cartwright MA, Wells DJ: Inflammatory responses following direct injection of plasmid DNA into skeletal muscle. Gene Ther (1998) 5:1283-1290.
-
(1998)
Gene Ther
, vol.5
, pp. 1283-1290
-
-
McMahon, J.M.1
Wells, K.E.2
Bamfo, J.E.3
Cartwright, M.A.4
Wells, D.J.5
-
135
-
-
0032080647
-
Cationic lipids enhance cytokine and cell influx levels in the lung following administration of plasmid: Cationic lipid complexes
-
Freimark BD, Blezinger HP, Florack VJ, Nordstrom JL, Long SD, Deshpande DS, Nochumson S, Petrak KL: Cationic lipids enhance cytokine and cell influx levels in the lung following administration of plasmid: cationic lipid complexes. J Immunol (1998) 160:4580-4586. Demonstration that cationic lipid complexes, more so than plasmid DNA or lipid alone, is capable of causing cytokine release and cellular influx following administered to the lungs of mice.
-
(1998)
J Immunol
, vol.160
, pp. 4580-4586
-
-
Freimark, B.D.1
Blezinger, H.P.2
Florack, V.J.3
Nordstrom, J.L.4
Long, S.D.5
Deshpande, D.S.6
Nochumson, S.7
Petrak, K.L.8
-
136
-
-
0029956357
-
Hexameric palindromic oligonucleotides with 5′-CG-3′ motif(s) induce production of interferon
-
Sonehara K, Saito H, Kuramoto E, Yamamoto S, Yamamoto T, Tokunaga T: Hexameric palindromic oligonucleotides with 5′-CG-3′ motif(s) induce production of interferon. J Interferon Cytokine Res (1996) 16:799-803.
-
(1996)
J Interferon Cytokine Res
, vol.16
, pp. 799-803
-
-
Sonehara, K.1
Saito, H.2
Kuramoto, E.3
Yamamoto, S.4
Yamamoto, T.5
Tokunaga, T.6
-
137
-
-
0030830849
-
Cationic liposomes are a strong adjuvant for a DNA vaccine of human immunodeficiency virus type 1
-
Ishii N, Fukushima J, Kaneko T, Okada E, Tani K, Tanaka SI, Hamajima K, Xin KQ, Kawamoto S, Koff W, Nishioka K, Yasuda T, Okuda K: Cationic liposomes are a strong adjuvant for a DNA vaccine of human immunodeficiency virus type 1. AIDS Res Hum Retroviruses (1997) 13:1421-1428.
-
(1997)
AIDS Res Hum Retroviruses
, vol.13
, pp. 1421-1428
-
-
Ishii, N.1
Fukushima, J.2
Kaneko, T.3
Okada, E.4
Tani, K.5
Tanaka, S.I.6
Hamajima, K.7
Xin, K.Q.8
Kawamoto, S.9
Koff, W.10
Nishioka, K.11
Yasuda, T.12
Okuda, K.13
-
138
-
-
0032152333
-
Lipofection indirectly increases expression of endogenous major histocompatibility complex class I molecules on tumor cells
-
Fox BA, Drury M, Hu H-M, Cao Z, Huntzicker EG, Qie W, Urba WJ: Lipofection indirectly increases expression of endogenous major histocompatibility complex class I molecules on tumor cells. Cancer Gene Ther (1998) 5:307-312.
-
(1998)
Cancer Gene Ther
, vol.5
, pp. 307-312
-
-
Fox, B.A.1
Drury, M.2
Hu, H.-M.3
Cao, Z.4
Huntzicker, E.G.5
Qie, W.6
Urba, W.J.7
-
139
-
-
0030670810
-
Toxicity and immunomodulatory activity of liposomal vectors formulated with cationic lipids toward immune effector cells
-
Filion MC, Phillips NC: Toxicity and immunomodulatory activity of liposomal vectors formulated with cationic lipids toward immune effector cells. Biochim Biophys Acta (1997) 1329:345-356.
-
(1997)
Biochim Biophys Acta
, vol.1329
, pp. 345-356
-
-
Filion, M.C.1
Phillips, N.C.2
-
140
-
-
0028111256
-
Liposome mediated depletion of macrophages: Mechanism of action, preparation of liposomes and applications
-
Van Rooijen N, Sanders A: Liposome mediated depletion of macrophages: mechanism of action, preparation of liposomes and applications. J Immunol Methods (1994) 174:83-93.
-
(1994)
J Immunol Methods
, vol.174
, pp. 83-93
-
-
Van Rooijen, N.1
Sanders, A.2
-
141
-
-
0026878142
-
Gene transfer in vivo with DNA-liposome complexes: Safety and acute toxicity in mice
-
Stewart MJ, Plautz GE, Del Buono L, Yang ZY, Xu L, Gao X, Huang L, Nabel EG, Nabel GJ: Gene transfer in vivo with DNA-liposome complexes: safety and acute toxicity in mice. Hum Gene Ther (1992) 3:267-275.
-
(1992)
Hum Gene Ther
, vol.3
, pp. 267-275
-
-
Stewart, M.J.1
Plautz, G.E.2
Del Buono, L.3
Yang, Z.Y.4
Xu, L.5
Gao, X.6
Huang, L.7
Nabel, E.G.8
Nabel, G.J.9
-
142
-
-
0029144352
-
Cancer gene therapy using plasmid DNA: Safety evaluation in rodents and non-human primates
-
Parker SE, Vahlsing HL, Serfilippi LM, Franklin CL, Doh SG, Gromkowski SH, Lew D, Manthorpe M, Norman J: Cancer gene therapy using plasmid DNA: safety evaluation in rodents and non-human primates. Hum Gene Ther (1995) 6:575-590.
-
(1995)
Hum Gene Ther
, vol.6
, pp. 575-590
-
-
Parker, S.E.1
Vahlsing, H.L.2
Serfilippi, L.M.3
Franklin, C.L.4
Doh, S.G.5
Gromkowski, S.H.6
Lew, D.7
Manthorpe, M.8
Norman, J.9
-
143
-
-
0032579975
-
Liposomal transfection efficiency and toxicity on glioma cell lines: In vitro and in vivo studies
-
Bell H, Kimber WI, Li M, Whittle IR: Liposomal transfection efficiency and toxicity on glioma cell lines: in vitro and in vivo studies. Neuroreport (1998) 9:793-798.
-
(1998)
Neuroreport
, vol.9
, pp. 793-798
-
-
Bell, H.1
Kimber, W.I.2
Li, M.3
Whittle, I.R.4
-
144
-
-
0030811950
-
DC-Chol liposome-mediated gene transfer in rat spinal cord
-
Yang K, Mu XS, Hayes RL, Qin YH, Sorgi FL, Huang L, Clifton GL: DC-Chol liposome-mediated gene transfer in rat spinal cord. Neuroreport (1997) 8:2355-2358.
-
(1997)
Neuroreport
, vol.8
, pp. 2355-2358
-
-
Yang, K.1
Mu, X.S.2
Hayes, R.L.3
Qin, Y.H.4
Sorgi, F.L.5
Huang, L.6
Clifton, G.L.7
-
145
-
-
0032469372
-
Transient human gene therapy: A novel cytokine regulatory strategy for experimental pancreatitis
-
Denham W, Denham D, Yang J, Carter G, MacKay S, Moldawer LL, Carey LC, Norman J: Transient human gene therapy: a novel cytokine regulatory strategy for experimental pancreatitis. Ann Surg (1998) 227:812-820.
-
(1998)
Ann Surg
, vol.227
, pp. 812-820
-
-
Denham, W.1
Denham, D.2
Yang, J.3
Carter, G.4
MacKay, S.5
Moldawer, L.L.6
Carey, L.C.7
Norman, J.8
-
146
-
-
9844237019
-
Safety of a single aerosol administration of escalating doses of the cationic lipid GL-67/DOPE/DMPE-PEG5000 formulation to the lungs of normal volunteers
-
Chadwick SL, Kingston HD, Stem M, Cook RM, O'Connor BJ, Lukasson M, Balfour RP, Rosenberg M, Cheng SH, Smith AE, Meeker DP, Geddes DM, Alton EW: Safety of a single aerosol administration of escalating doses of the cationic lipid GL-67/DOPE/DMPE-PEG5000 formulation to the lungs of normal volunteers. Gene Ther (1997) 4:937-942.
-
(1997)
Gene Ther
, vol.4
, pp. 937-942
-
-
Chadwick, S.L.1
Kingston, H.D.2
Stem, M.3
Cook, R.M.4
O'Connor, B.J.5
Lukasson, M.6
Balfour, R.P.7
Rosenberg, M.8
Cheng, S.H.9
Smith, A.E.10
Meeker, D.P.11
Geddes, D.M.12
Alton, E.W.13
-
147
-
-
0028600083
-
Safety and toxicity of catheter gene delivery to the pulmonary vasculature in a patient with metastatic melanoma
-
Nabel EG, Yang Z, Muller D, Chang AE, Gao X, Huang L, Cho KJ, Nabel GJ: Safety and toxicity of catheter gene delivery to the pulmonary vasculature in a patient with metastatic melanoma. Hum Gene Ther (1994) 5:1089-1094.
-
(1994)
Hum Gene Ther
, vol.5
, pp. 1089-1094
-
-
Nabel, E.G.1
Yang, Z.2
Muller, D.3
Chang, A.E.4
Gao, X.5
Huang, L.6
Cho, K.J.7
Nabel, G.J.8
-
148
-
-
0030662578
-
DNA Vaccines: Safety and efficacy issues
-
Klinman DM, Takeno M, Ichino M, Gu M, Yamshchikov G, Mor G, Conover J: DNA Vaccines: safety and efficacy issues. Springer Semin Immunopathol (1997) 19:245-256.
-
(1997)
Springer Semin Immunopathol
, vol.19
, pp. 245-256
-
-
Klinman, D.M.1
Takeno, M.2
Ichino, M.3
Gu, M.4
Yamshchikov, G.5
Mor, G.6
Conover, J.7
-
149
-
-
0028803897
-
Evaluation in vitro and in vivo of cationic liposome-expression construct complexes for cystic fibrosis gene therapy
-
McLachlan G, Davidson DJ, Stevenson BJ, Dickinson P, Davidson Smith H, Dorin JR, Porteous DJ: Evaluation in vitro and in vivo of cationic liposome-expression construct complexes for cystic fibrosis gene therapy. Gene Ther (1995) 2:614-622.
-
(1995)
Gene Ther
, vol.2
, pp. 614-622
-
-
McLachlan, G.1
Davidson, D.J.2
Stevenson, B.J.3
Dickinson, P.4
Davidson Smith, H.5
Dorin, J.R.6
Porteous, D.J.7
-
150
-
-
0031750860
-
In vitro myotoxicity of selected cationic macromolecules used in non-viral gene therapy
-
Brazeau GA, Attia S, Poxon S, Hughes JA: In vitro myotoxicity of selected cationic macromolecules used in non-viral gene therapy. Pharm Res (1998) 15:680-684.
-
(1998)
Pharm Res
, vol.15
, pp. 680-684
-
-
Brazeau, G.A.1
Attia, S.2
Poxon, S.3
Hughes, J.A.4
-
151
-
-
0031884611
-
Beta-Galactosidase staining following intracoronary infusion of cationic liposomes in the in vivo rabbit heart is produced by microinfarction rather than effective gene transfer: A cautionary tale
-
Wright MJ, Rosenthal E, Stewart L, Wightman LM, Miller AD, Latchman DS, Marber MS: beta-Galactosidase staining following intracoronary infusion of cationic liposomes in the in vivo rabbit heart is produced by microinfarction rather than effective gene transfer: a cautionary tale. Gene Ther (1998) 5:301-308.
-
(1998)
Gene Ther
, vol.5
, pp. 301-308
-
-
Wright, M.J.1
Rosenthal, E.2
Stewart, L.3
Wightman, L.M.4
Miller, A.D.5
Latchman, D.S.6
Marber, M.S.7
-
152
-
-
0031023264
-
Stabilization of cationic liposome-plasmid DNA complexes by polyamines and poly(ethylene glycol)-phospholipid conjugates for efficient in vivo gene therapy
-
Hong K, Zheng W, Baker A, Papahadjopoulos D: Stabilization of cationic liposome-plasmid DNA complexes by polyamines and poly(ethylene glycol)-phospholipid conjugates for efficient in vivo gene therapy. FEBS Lett (1997) 400:233-237.
-
(1997)
FEBS Lett
, vol.400
, pp. 233-237
-
-
Hong, K.1
Zheng, W.2
Baker, A.3
Papahadjopoulos, D.4
-
153
-
-
0028842728
-
Engineering Liposomes for drug delivery: Progress and problems
-
Gregoriadis G: Engineering Liposomes for drug delivery: progress and problems. Trends Biotechnol (1995) 13:527-537.
-
(1995)
Trends Biotechnol
, vol.13
, pp. 527-537
-
-
Gregoriadis, G.1
-
154
-
-
0028812620
-
Cationic liposome-mediated intravenous gene delivery
-
Liu Y, Liggitt D, Zhong W, Tu G, Gaensler K, Debs R: Cationic liposome-mediated intravenous gene delivery. J Biol Chem (1995) 270:24864-24870.
-
(1995)
J Biol Chem
, vol.270
, pp. 24864-24870
-
-
Liu, Y.1
Liggitt, D.2
Zhong, W.3
Tu, G.4
Gaensler, K.5
Debs, R.6
-
155
-
-
0032150355
-
Immunotherapy of established tumors in mice by intratumoral injection of interleukin-2 plasmid DNA: Induction of CD8+ T-cell immunity
-
Saffran DC, Norton HM, Yankauckas MA, Anderson D, Barnhart KM, Abai AM, Hobart P, Manthorpe M, Norman JA, Parker SE: Immunotherapy of established tumors in mice by intratumoral injection of interleukin-2 plasmid DNA: Induction of CD8+ T-cell immunity. Cancer Gene Ther (1998) 5:321-330.
-
(1998)
Cancer Gene Ther
, vol.5
, pp. 321-330
-
-
Saffran, D.C.1
Norton, H.M.2
Yankauckas, M.A.3
Anderson, D.4
Barnhart, K.M.5
Abai, A.M.6
Hobart, P.7
Manthorpe, M.8
Norman, J.A.9
Parker, S.E.10
-
156
-
-
25544465317
-
Intratumoral accumulation and activation of natural killer cells following cationic lipid-mediated gene transfer of a human IL-2 transgene
-
Clark PR, Parker SE, Hersh EM: Intratumoral accumulation and activation of natural killer cells following cationic lipid-mediated gene transfer of a human IL-2 transgene. Cancer Gene Ther (1998) 5:O24.
-
(1998)
Cancer Gene Ther
, vol.5
-
-
Clark, P.R.1
Parker, S.E.2
Hersh, E.M.3
-
157
-
-
0030757856
-
Gene therapy for peritoneal - Dissemination of pancreatic cancer by liposome-mediated transfer of herpes simplex virus thymidine kinase gene
-
Aoki K, Yoshida T, Matsumoto N, Ide H, Hosokawa K, Sugimura T, Terada M: Gene therapy for peritoneal - dissemination of pancreatic cancer by liposome-mediated transfer of herpes simplex virus thymidine kinase gene. Hum Gene Ther (1997) 8:1105-1113.
-
(1997)
Hum Gene Ther
, vol.8
, pp. 1105-1113
-
-
Aoki, K.1
Yoshida, T.2
Matsumoto, N.3
Ide, H.4
Hosokawa, K.5
Sugimura, T.6
Terada, M.7
-
158
-
-
25544458478
-
Gene therapy for peritonitis carcinomatosa using cationic liposome-mediated gene transfer
-
Meeting Abstract
-
Kikuchi A, Sugaya S, Tanaka K: Gene therapy for peritonitis carcinomatosa using cationic liposome-mediated gene transfer. Proc Annu Meet Am Assoc Cancer Res (1996) 37:A2389. (Meeting Abstract).
-
(1996)
Proc Annu Meet Am Assoc Cancer Res
, vol.37
-
-
Kikuchi, A.1
Sugaya, S.2
Tanaka, K.3
-
159
-
-
0030822208
-
Gene delivery by HVJ-liposome in the experimental gene therapy of murine glioma
-
Mabuchi E, Shimizu K, Miyao T, Kaneda Y, Kishima H, Tamura M, Ikenaka K, Hayakawa T: Gene delivery by HVJ-liposome in the experimental gene therapy of murine glioma. Gene Ther (1997) 4:768-772.
-
(1997)
Gene Ther
, vol.4
, pp. 768-772
-
-
Mabuchi, E.1
Shimizu, K.2
Miyao, T.3
Kaneda, Y.4
Kishima, H.5
Tamura, M.6
Ikenaka, K.7
Hayakawa, T.8
-
160
-
-
0028258785
-
Interferon-ß endogenously produced by intratumoral injection of cationic liposome-encapsulated gene: Cytocidal effect on glioma transplanted into nude mouse brain
-
Yagi K, Hayashi Y, Ishida N, Ohbayashi M, Ohishi N, Mizuno M, Yoshida J: Interferon-ß endogenously produced by intratumoral injection of cationic liposome-encapsulated gene: cytocidal effect on glioma transplanted into nude mouse brain. Biochem Mol Biol Int (1994) 32:167-171.
-
(1994)
Biochem Mol Biol Int
, vol.32
, pp. 167-171
-
-
Yagi, K.1
Hayashi, Y.2
Ishida, N.3
Ohbayashi, M.4
Ohishi, N.5
Mizuno, M.6
Yoshida, J.7
-
161
-
-
0030891397
-
In vivo Gene Therapy of Malignant Tumors with Heat Shock Protein-65 Gene
-
Lukacs KV, Nakakes A, Atkins CJ, Lowrie DB, Colston MJ: In vivo Gene Therapy of Malignant Tumors with Heat Shock Protein-65 Gene. Gene Ther (1997) 4:346-350.
-
(1997)
Gene Ther
, vol.4
, pp. 346-350
-
-
Lukacs, K.V.1
Nakakes, A.2
Atkins, C.J.3
Lowrie, D.B.4
Colston, M.J.5
-
162
-
-
25544439626
-
Cancer gene therapy with a heat shock protein gene
-
Lukacs, KV, Steel, RM, Oakley, RE, Pardo DE, Porter CD, Sorgi F, Huang L, Geddes DM, Alton EWFW: Cancer gene therapy with a heat shock protein gene. Cancer Gene Ther (1997) 4:S51.
-
(1997)
Cancer Gene Ther
, vol.4
-
-
Lukacs, K.V.1
Steel, R.M.2
Oakley, R.E.3
Pardo, D.E.4
Porter, C.D.5
Sorgi, F.6
Huang, L.7
Geddes, D.M.8
Alton, E.W.F.W.9
-
163
-
-
0030944023
-
Bioactivity of autologous irradiated renal cell carcinoma vaccines generated by ex vivo granulocyte-macrophage colony-stimulating factor gene transfer
-
Simons JW, Jaffee EM, Weber CE, Levitsky HI, Nelson WG, Carducci MA, Lazenby AJ, Cohen LK, Finn CC, Clift SM, Hauda KM, Beck LA, Leiferman KM, Owens AH Jr, Piantadosi S, Dranoff G, Mulligan RC, Pardoll DM, Marshall FF: Bioactivity of autologous irradiated renal cell carcinoma vaccines generated by ex vivo granulocyte-macrophage colony-stimulating factor gene transfer. Cancer Res (1997) 57:1537-1546.
-
(1997)
Cancer Res
, vol.57
, pp. 1537-1546
-
-
Simons, J.W.1
Jaffee, E.M.2
Weber, C.E.3
Levitsky, H.I.4
Nelson, W.G.5
Carducci, M.A.6
Lazenby, A.J.7
Cohen, L.K.8
Finn, C.C.9
Clift, S.M.10
Hauda, K.M.11
Beck, L.A.12
Leiferman, K.M.13
Owens Jr., A.H.14
Piantadosi, S.15
Dranoff, G.16
Mulligan, R.C.17
Pardoll, D.M.18
Marshall, F.F.19
-
164
-
-
17344365479
-
A Phase I Study of Adenovirus-Mediated Wild-Type p53 Gene Transfer in Patients with Advanced Non-Small Cell Lung Cancer
-
Schuler M, Rochlitz C, Horowitz JA, Schlegal J, Perruchoud AP, Kommoss F, Bollinger CT, Kauczor H-U, Dalquen P, Fritz MA, Swanson S, Herrmann R, Huber C: A Phase I Study of Adenovirus-Mediated Wild-Type p53 Gene Transfer in Patients with Advanced Non-Small Cell Lung Cancer. Hum Gene Ther (1998) 9:2075-2082.
-
(1998)
Hum Gene Ther
, vol.9
, pp. 2075-2082
-
-
Schuler, M.1
Rochlitz, C.2
Horowitz, J.A.3
Schlegal, J.4
Perruchoud, A.P.5
Kommoss, F.6
Bollinger, C.T.7
Kauczor, H.-U.8
Dalquen, P.9
Fritz, M.A.10
Swanson, S.11
Herrmann, R.12
Huber, C.13
-
165
-
-
0031463632
-
Therapy of malignant brain tumors by intratumoral implantation of retroviral vector-producing cells
-
Ram Z, Culver KW, Oshiro EM, Viola JJ, DeVroom HL, Otto E, Long Z, Chiang Y, McGarrity GJ, Muul LM, Katz D, Blaese RM, Oldfield EH: Therapy of malignant brain tumors by intratumoral implantation of retroviral vector-producing cells. Nature Med (1997) 3:1354-1361.
-
(1997)
Nature Med
, vol.3
, pp. 1354-1361
-
-
Ram, Z.1
Culver, K.W.2
Oshiro, E.M.3
Viola, J.J.4
DeVroom, H.L.5
Otto, E.6
Long, Z.7
Chiang, Y.8
McGarrity, G.J.9
Muul, L.M.10
Katz, D.11
Blaese, R.M.12
Oldfield, E.H.13
-
166
-
-
0030984929
-
The TMC Worldwide Gene Therapy Enrollment Report, End 1996
-
Marcel T, Grausz JD: The TMC Worldwide Gene Therapy Enrollment Report, End 1996. Hum Gene Ther (1997) 8:775-800.
-
(1997)
Hum Gene Ther
, vol.8
, pp. 775-800
-
-
Marcel, T.1
Grausz, J.D.2
-
167
-
-
0030463013
-
Immune response in human melanoma after transfer of an allogeneic class I major histocompatibility complex gene with DNA-liposome complexes
-
Nabel GJ, Gordon D, Bishop DK, Nickoloff BJ, Yang ZY, Aruga A, Cameron MJ, Nabel EG, Chang AE: Immune response in human melanoma after transfer of an allogeneic class I major histocompatibility complex gene with DNA-liposome complexes. Proc Natl Acad Sci USA (1996) 93:15388.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 15388
-
-
Nabel, G.J.1
Gordon, D.2
Bishop, D.K.3
Nickoloff, B.J.4
Yang, Z.Y.5
Aruga, A.6
Cameron, M.J.7
Nabel, E.G.8
Chang, A.E.9
-
168
-
-
0029804407
-
Direct transfer of a foreign MHC gene into human melanoma alters T cell receptor V beta usage by tumor infiltrating lymphocytes
-
DeBruyne LA, Chang AE, Cameron MJ, Yang Z, Gordon D, Nabel EG, Nabel GJ, Bishop DK: Direct transfer of a foreign MHC gene into human melanoma alters T cell receptor V beta usage by tumor infiltrating lymphocytes. Cancer Immunol Immunother (1996) 43:49-58. Evidence for an altered TCR usage by TIL in tumor nodules following intratumoral gene transfer.
-
(1996)
Cancer Immunol Immunother
, vol.43
, pp. 49-58
-
-
Debruyne, L.A.1
Chang, A.E.2
Cameron, M.J.3
Yang, Z.4
Gordon, D.5
Nabel, E.G.6
Nabel, G.J.7
Bishop, D.K.8
-
169
-
-
2442770764
-
Phase I gene therapy study of HLA-B7 transduction by direct injection in malignant melanoma
-
Washington, DC
-
Silver HKG, Klasa RJ, Baily MB, LeRiche JC, Stahl SM, Schreiber AB: 'Phase I gene therapy study of HLA-B7 transduction by direct injection in malignant melanoma.' Proc Am Assoc Cancer Res Washington, DC (1996) 342.
-
(1996)
Proc Am Assoc Cancer Res
, pp. 342
-
-
Silver, H.K.G.1
Klasa, R.J.2
Baily, M.B.3
LeRiche, J.C.4
Stahl, S.M.5
Schreiber, A.B.6
-
170
-
-
0344745654
-
Clinical Experience in Phase I and Phase II Testing of Direct Intratumoral Administration with Allovectin-7: A Gene-Based Immunotherapeutic Agent
-
Vogelzang NJ, Sudakoff G, Hersh EM, Stopeck A, Rubin J, Schreiber A, Stahl S: Clinical Experience in Phase I and Phase II Testing of Direct Intratumoral Administration with Allovectin-7: A Gene-Based Immunotherapeutic Agent. Proc Am Soc Clin Oncol (1996) 15:235.
-
(1996)
Proc Am Soc Clin Oncol
, vol.15
, pp. 235
-
-
Vogelzang, N.J.1
Sudakoff, G.2
Hersh, E.M.3
Stopeck, A.4
Rubin, J.5
Schreiber, A.6
Stahl, S.7
-
171
-
-
2442750523
-
Phase II Study of Intratumoral Injection of HLA-B7/β2M Plasmid DNA-Cationic Lipid Complex (Allovectin-7) Therapy for Metastatic Malignant melanoma (MMM)
-
Hersh EM, Stopeck AT, Silver HKB, Chang AE, Doroshow JH, Rubin J; Rinehart J, Stahl SM, Schreiber AB: Phase II Study of Intratumoral Injection of HLA-B7/β2M Plasmid DNA-Cationic Lipid Complex (Allovectin-7) Therapy for Metastatic Malignant melanoma (MMM). Cancer Gene Ther (1997) 4:S48.
-
(1997)
Cancer Gene Ther
, vol.4
-
-
Hersh, E.M.1
Stopeck, A.T.2
Silver, H.K.B.3
Chang, A.E.4
Doroshow, J.H.5
Rubin, J.6
Rinehart, J.7
Stahl, S.M.8
Schreiber, A.B.9
-
172
-
-
0343739128
-
A Phase I study of intra-lesional (IL) gene therapy in metastatic renal cell cancer (RCC)
-
Vogelzang NJ, Sudakoff G, McKay S, Lestingi T, Stahl S: A Phase I study of intra-lesional (IL) gene therapy in metastatic renal cell cancer (RCC). Proc Am Soc Clin Oncol (1995) 14:A641.
-
(1995)
Proc Am Soc Clin Oncol
, vol.14
-
-
Vogelzang, N.J.1
Sudakoff, G.2
McKay, S.3
Lestingi, T.4
Stahl, S.5
-
173
-
-
8244224532
-
Phase I study of Immunotherapy of Hepatic Metastases of Colorectal Carcinoma by Direct Gene Transfer of an Allogeneic Histocompatibility Antigen, HLA-B7
-
Rubin G, Galanis E, Pitot HC, Richardson RL, Burch PA, Charboneau JW, Reading CC, Lewis BD, Stahl S, Akporiaye ET, Harris DT: Phase I study of Immunotherapy of Hepatic Metastases of Colorectal Carcinoma by Direct Gene Transfer of an Allogeneic Histocompatibility Antigen, HLA-B7. Gene Ther (1997) 4:419-425.
-
(1997)
Gene Ther
, vol.4
, pp. 419-425
-
-
Rubin, G.1
Galanis, E.2
Pitot, H.C.3
Richardson, R.L.4
Burch, P.A.5
Charboneau, J.W.6
Reading, C.C.7
Lewis, B.D.8
Stahl, S.9
Akporiaye, E.T.10
Harris, D.T.11
-
174
-
-
0031661598
-
Alloantigen gene therapy for squamous cell carcinoma of the head and neck results of a phase I trial
-
Gleich LL, Gluckman JL, Armstrong S, Biddinger PW, Miller MA, Balakrishnan K, Wilson KM, Saavedra HL, Stambrook PJ: Alloantigen gene therapy for squamous cell carcinoma of the head and neck results of a phase I trial. Arch Otolaryngol Head Neck Surg (1998) 124:1097-1104.
-
(1998)
Arch Otolaryngol Head Neck Surg
, vol.124
, pp. 1097-1104
-
-
Gleich, L.L.1
Gluckman, J.L.2
Armstrong, S.3
Biddinger, P.W.4
Miller, M.A.5
Balakrishnan, K.6
Wilson, K.M.7
Saavedra, H.L.8
Stambrook, P.J.9
-
175
-
-
0030845845
-
Phase I study of immunotherapy of cutaneous metastases of human carcinoma using allogeneic and xenogeneic MHC DNA-liposome complexes
-
Hui KM, Ang PT, Huang L, Tay SK: Phase I study of immunotherapy of cutaneous metastases of human carcinoma using allogeneic and xenogeneic MHC DNA-liposome complexes. Gene Ther (1997) 4:783-790.
-
(1997)
Gene Ther
, vol.4
, pp. 783-790
-
-
Hui, K.M.1
Ang, P.T.2
Huang, L.3
Tay, S.K.4
-
176
-
-
0004502597
-
Results of a Phase I Study of Direct Gene Transfer of Interieukin-2 (IL-2) Formulated with Cationic Lipid Vector, Leuvectin, in Patients with metastatic solid Tumors
-
Stopeck A, Hersh E, Wameke J, Ungeer E, Rinehart J, Schreiber A, Stahl S: Results of a Phase I Study of Direct Gene Transfer of Interieukin-2 (IL-2) Formulated with Cationic Lipid Vector, Leuvectin, in Patients with metastatic solid Tumors. Proc Am Soc Clin Oncol (1996) 15:235.
-
(1996)
Proc Am Soc Clin Oncol
, vol.15
, pp. 235
-
-
Stopeck, A.1
Hersh, E.2
Wameke, J.3
Ungeer, E.4
Rinehart, J.5
Schreiber, A.6
Stahl, S.7
-
177
-
-
25544466243
-
Phase I/II Trial of the IL-2 DNA/DMRIE/DOPE Lipid Complex as an Immunotherapeutic Agent by Direct Gene Transfer in Patients with Advanced Melanoma, Renal Cell Carcinoma, and Sarcoma
-
Rubin J, Galanis E, Burch P, Hersh EM, Spier C, Akporiaye E, Gonzalez R, Rinehart JJ, Sobol RE, Sondak VK, Stahl SM: Phase I/II Trial of the IL-2 DNA/DMRIE/DOPE Lipid Complex as an Immunotherapeutic Agent by Direct Gene Transfer in Patients with Advanced Melanoma, Renal Cell Carcinoma, and Sarcoma. Cancer Gene Ther (1997) 4:S49.
-
(1997)
Cancer Gene Ther
, vol.4
-
-
Rubin, J.1
Galanis, E.2
Burch, P.3
Hersh, E.M.4
Spier, C.5
Akporiaye, E.6
Gonzalez, R.7
Rinehart, J.J.8
Sobol, R.E.9
Sondak, V.K.10
Stahl, S.M.11
-
178
-
-
0029856188
-
A New Cationic Liposome DNA Complex Enhances the Efficiency of Arterial Gene Transfer in vivo
-
Stephan DJ, Yang Z-Y, San H, Simari RD, Wheeler CJ, Felgner PL, Gordon D, Nabel GJ, Nabel EG: A New Cationic Liposome DNA Complex Enhances the Efficiency of Arterial Gene Transfer in vivo. Hum Gene Ther (1996) 7:1803-1812.
-
(1996)
Hum Gene Ther
, vol.7
, pp. 1803-1812
-
-
Stephan, D.J.1
Yang, Z.-Y.2
San, H.3
Simari, R.D.4
Wheeler, C.J.5
Felgner, P.L.6
Gordon, D.7
Nabel, G.J.8
Nabel, E.G.9
-
179
-
-
0028939896
-
Targeted gene transfer into hepatoma cells with lipopolyamine- Condensed DNA particles presenting galactose ligands: A stage toward artificial viruses
-
Remy JS, Kichler A, Mordvinov V, Schuber F, Behr JP: Targeted gene transfer into hepatoma cells with lipopolyamine-condensed DNA particles presenting galactose ligands: a stage toward artificial viruses. Proc Natl Acad Sci USA (1995) 92:1744-1748.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 1744-1748
-
-
Remy, J.S.1
Kichler, A.2
Mordvinov, V.3
Schuber, F.4
Behr, J.P.5
-
180
-
-
0030778998
-
Anit-HER2 immunoliposomes for targeted therapy of human tumors
-
Park JW, Hong K, Kirpotin DB, Meyer O, Papahadjopoulos D, Benz CC: Anit-HER2 immunoliposomes for targeted therapy of human tumors. Cancer Lett (1997) 118:153-160.
-
(1997)
Cancer Lett
, vol.118
, pp. 153-160
-
-
Park, J.W.1
Hong, K.2
Kirpotin, D.B.3
Meyer, O.4
Papahadjopoulos, D.5
Benz, C.C.6
-
181
-
-
0029872098
-
Nuclear targeting of SV40 and adenovirus
-
Greber UF, Kasamatsu H: Nuclear targeting of SV40 and adenovirus. Trends Cell Biol (1996) 6:189-195.
-
(1996)
Trends Cell Biol
, vol.6
, pp. 189-195
-
-
Greber, U.F.1
Kasamatsu, H.2
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