Pulmonary surfactant inhibits cationic liposome-mediated gene delivery to respiratory epithelial cells in vitro

Human Gene Therapy

Volumn 8, Issue 4, 1997, Pages 431-438

  Duncan, James E ^a   Whitsett, Jeffrey A ^b,c   Horowitz, Ann D ^b  

^a DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CINCINNATI CHILDREN S HOSPITAL RESEARCH FOUNDATION   (United States)

^c CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LUNG SURFACTANT; PHOSPHOLIPID; SURFACTANT ASSOCIATED PROTEIN;

ANIMAL CELL; ARTICLE; EPITHELIUM CELL; GENE TARGETING; GENETIC TRANSFECTION; MOUSE; NONHUMAN; PLASMID; REPORTER GENE; RESPIRATORY EPITHELIUM;

ANIMALIA;

EID: 0030974582     PISSN: 10430342     EISSN: None     Source Type: Journal    
DOI: 10.1089/hum.1997.8.4-431     Document Type: Article

References (31)

1. ALTON, E.W.F.W., MIDDLETON, P.G., CAPLEN, N.J., SMITH, S.N., STEEL, D.M., MUNKONGE, F.M., JEFFREY, P.K., GEDDES, D.M., HART, S.L., WILLIAMSON, R., FASOLD, K.I., MILLER, A.D., DICKINSON, P., STEVENSON, B.J., McLACHLAN, G., DORIN, J.R., and PORTEOUS, D.J. (1993). Non-invasive liposome-mediated gene delivery can correct the ion transport defect in cystic fibrosis mutant mice. Nature Genet. 5, 135-142.
2. BENNETT, M.J., NANTZ, M.H., BALASUBRAMANIAM, R.P., GRUENERT, D.C., and MALONE, R.W. (1995). Cholesterol enhances cationic liposome-mediated DNA transfection of human respiratory epithelial cells. Biosci. Rep. 15, 47-53.
3. BRESLIN, J.S., and WEAVER, T.E. (1992). Binding, uptake, and localization of surfactant protein B in isolated rat alveolar type II cells. Am. J. Physiol. 262 (Lung Cell. Mol. Physiol. 6, L699-L707.
4. CANONICO, A.E., CONARY, J.T., MEYRICK, B.O., and BRIGHAM, K.L. (1994). No lung toxicity after repeated aerosol or intravenous delivery of plasmid-cationinc liposome complexes. J. Appl. Physiol. 77, 415-419.
5. DE WET, J.R., WOOD, K.V., DELUCA, M., HELINKI, D.R., and SUBRAMANI, S. (1987). Firefly luciferase gene: structure and expression in mammalian cells. Mol. Cell. Biol. 7, 725-737.
6. DUCK-CHONG, C.G. (1979). A rapid sensitive method for determining phospholipid phosphorus involving digestion with magnesium nitrate. Lipids 14, 492-497.
7. DUZGUNES, N., ALLEN, T.M., FEDOR, J., and PAPAHADJOPOULOS, D. (1987). Lipid mixing during membrane aggregation and fusion: Why fusion assays disagree. Biochemistry 26, 8435-8442.
8. FASBENDER, A.J., ZABNER, J., and WELSH, M.J. (1995). Optimization of cationic lipid-mediated gene transfer to airway epithelia. Am. J. Physiol. 269 (Lung Cell. Mol. Physiol. 13), L45-L51.
9. FELGNER, J.H., KUMAR, R., SRIDHAR, C.N., WHEELER, C.J., TSAI, Y.J., BORDER, R., RAMSEY, P., MARTIN, M., and FELGNER, P.L. (1994). Enhanced gene delivery and mechanism studies with a novel series of cationic lipid formulations. J. Biol. Chem. 269, 2550-2561.
10. GREGORY, T.J., LONGMORE, W.J., MOXLEY, M.A., WHITSETT, J.A., REED, C.A., FOWLER, A.A.I., HUDSON, L.D., MAUNDER, R.J., CRIM, C., and HYERS, T.M. (1991). Surfactant chemical composition and biophysical activity in acute respiratory distress syndrome. J. Clin. Invest. 8, 1976-1981.
11. HOROWITZ, A.D., MOUSSAVIAN, B., and WHITSETT, J.A. (1996). Roles of SP-A, SP-B, SP-C in modulation of lipid uptake by pulmonary epithelial cells in vitro. Am. J. Physiol. 270 (Lung Cell. Mol. Physiol. 14), L69-L79.
12. HUG, P., and SLEIGHT, R.G. (1991). Liposomes for the transformation of eukaryotic cells. Biochim. Biophys. Acta 1097, 1-17.
13. LAEMMLI, U.K. (1970). Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685.
14. LOGAN, J.J., BEBOK, Z., WALKER, L.C., PENG, S., FELGNER, P.L., SIEGAL, G.P., FRIZZELL, R.A., DONG, J., HOWARD, M., MATALON, S., LINDSEY, J.R., DUVALL, M., and SORSCHER, E.J. (1995). Cationic lipids for reporter gene and CFTR transfer to rat pulmonary epithelium. Gene Ther. 2, 38-49.
15. NABEL, G.J., CHANG, A., NABEL, E.J., PLAUTZ, G.E., ENSMINGER, W., FOX, B.A., FELGNER, P., SHU, S., and CHO, K. (1994). Immunotherapy of malignancy by in vivo gene transfer into tumors. Hum. Gene Ther. 5, 57-77.
16. OOSTERLAKEN-DIJKSTERHUIS, M.A., HAAGSMAN, H.P., VAN GOLDE, L.M.G., and DEMEL, R.A. (1991a). Characterization of lipid insertion into monomolecular layers mediated by lung surfactant proteins SP-B and SP-C. Biochemistry 30, 10965-10971.
17. OOSTERLAKEN-DIJKSTERHUIS, M.A., VAN EIJK, M., VAN BUEL, B.L.M., VAN GOLDE, L.M.G., and HAAGSMAN, H.P. (1991b). Surfactant protein composition of lamellar bodies isolated from rat lung. Biochem. J. 274, 115-119.
18. OOSTERLAKEN-DIJKSTERHUIS, M.A., VAN EIJK, M., VAN GOLDE, L.M.G., and HAAGSMAN, H.P. (1992). Lipid mixing is mediated by the hydrophobic surfactant protein SP-B but not by SP-C. Biochim. Biophys. Acta 1110, 45-50.
19. POULAIN, F.R., ALLEN, L., WILLIAMS, M.C., HAMILTON, R.L., and HAWGOOD, S. (1992). Effects of surfactant apolipoproteins on liposome structure: implications for tubular myelin formation. Am. J. Physiol. 262, L730-L739.
20. REBELLO, C.M., JOBE, A.H., EISELE, J.W., and IKEGAMI, M. (1996). Alveolar and tissue surfactant pool sizes in humans. Am. J. Respir. Crit. Care Med. 154, 625-628.
21. RICE, W.R., SARIN, V.K., FOX, J.L., BAATZ, J., WERT, S., and WHITSETT, J.A. (1989). Surfactant peptides stimulate uptake of phosphatidylcholine by isolated cells. Biochim. Biophys. Acta 1006, 237-245.
22. SMITH, P.K., KROHN, R.I., HERMANSON, G.T., MALLIA, A.K., GARTNER, F.H., PROVENZANO, M.D., FUJIMOTO, E.K., GOEKE, N.M., OLSON, B.J., and KLENK, D.C. (1985). Measurement of protein using bicinchoninic acid. Anal. Biochem. 150, 76-85.
23. TSAN, M.F., WHITE, J.E., and SHEPARD, B. (1995). Lung-specific direct in vivo gene transfer with recombinant plasmid DNA. Am. J. Physiol. 268, L1052-L1056.
24. VAN EIJK, M., DEHAAS, C.G.M., and HAAGSMAN, H.P. (1995). Quantitative analysis of pulmonary surfactant proteins B and C. Anal. Biochem. 232, 231-237.
25. WEAVER, T.E., and WHITSETT, J.A. (1991). Function and regulation of expression of pulmonary surfactant-associated proteins. Biochem. J. 273, 249-264.
26. WIKENHEISER, K.A., VORBROKER, D.K., RICE, W.R., CLARK, J.C., BACHURSKI, C.J., OIE, H.K., and WHITSETT, J.A. (1993). Production of immortalized distal respiratory epithelial cell lines from surfactant protein C/simian virus 40 large antigen transgenic mice. Proc. Natl. Acad. Sci. USA 90, 11029-11033.
27. r = 26,000-36,000 enhances uptake of liposomes by type II cells. J. Biol. Chem. 262, 2888-2894.
28. WROBEL, I., and COLLINS, D. (1995). Fusion of cationic liposomes with mammalian cells occurs after endocytosis. Biochim. Biophys. Acta 1235, 296-304.
29. XU, Y., and SZOKA, F.C. (1996). Mechanism of DNA release from cationic liposome/DNA complexes used in cell transfection. Biochemistry 35, 5616-5623.
30. YOSHIMURA, K., ROSENFELD, M.A., NAKAMURA, H., SCHERER, E.M., PAVIRANI, A., LECOCQ, J.P., and CRYSTAL, R.G. (1992). Expression of the human cystic fibrosis transmembrane conductance regulator gene in the mouse lung after in vivo intratracheal plasmid-mediated gene transfer. Nucleic Acids Res. 20, 3233-3240.
31. ZABNER, J., FASSENDER, A.J., MONINGER, T., POELLINGER, K.A., and WELSH, M.J. (1995). Cellular and molecular barriers to gene transfer by a cationic lipid. J. Biol. Chem. 70, 18997-19007.