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Volumn 5, Issue 1, 1998, Pages 91-98

The effect of mucolytic agents on gene transfer across a CF sputum barrier in vitro

Author keywords

Cystic fibrosis; Gene therapy; rhDNase; Sputum

Indexed keywords

ACETYLCYSTEINE; BETA GALACTOSIDASE; DEOXYRIBONUCLEASE; DNA; DORNASE ALFA; LIPOSOME; LYASE; LYSINE; MUCOLYTIC AGENT; NACYSTELYN; UNCLASSIFIED DRUG;

EID: 6844266288     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3300556     Document Type: Article
Times cited : (109)

References (39)
  • 1
    • 0024453308 scopus 로고
    • Identification of the cystic fibrosis gene: Chromosome walking and jumping
    • Rommens JM et al. Identification of the cystic fibrosis gene: chromosome walking and jumping. Science 1989, 245: 1059-1065.
    • (1989) Science , vol.245 , pp. 1059-1065
    • Rommens, J.M.1
  • 2
    • 0024424270 scopus 로고
    • Identification of the cystic fibrosis gene: Cloning and characterization of complementary DNA
    • Riordan JR et al. Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA. Science 1989; 245: 1066-1073.
    • (1989) Science , vol.245 , pp. 1066-1073
    • Riordan, J.R.1
  • 3
    • 0024423668 scopus 로고
    • Identification of the cystic fibrosis gene: Genetic analysis
    • Kerem B et al. Identification of the cystic fibrosis gene: genetic analysis. Science 1989; 245: 1073-1080.
    • (1989) Science , vol.245 , pp. 1073-1080
    • Kerem, B.1
  • 4
    • 1542648827 scopus 로고
    • Adenovirus-mediated gene transfer transiently corrects the chloride defect in nasal epithelia of patients with cystic fibrosis
    • Zabner J et al. Adenovirus-mediated gene transfer transiently corrects the chloride defect in nasal epithelia of patients with cystic fibrosis. Cell 1993; 75: 1-20.
    • (1993) Cell , vol.75 , pp. 1-20
    • Zabner, J.1
  • 5
    • 0028168641 scopus 로고
    • Administration of an adenovirus containing human CFTR cDNA to the respiratory tract of individuals with cystic fibrosis
    • Crystal RG et al. Administration of an adenovirus containing human CFTR cDNA to the respiratory tract of individuals with cystic fibrosis. Nat Genet 1994; 8: 42-51.
    • (1994) Nat Genet , vol.8 , pp. 42-51
    • Crystal, R.G.1
  • 6
    • 0028913411 scopus 로고
    • Liposome-mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis
    • Caplen NJ et al. Liposome-mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis. Nature Med 1995; 1: 39-46.
    • (1995) Nature Med , vol.1 , pp. 39-46
    • Caplen, N.J.1
  • 7
    • 0029100239 scopus 로고
    • A controlled study of adenoviral-vector-mediated gene transfer in the nasal epithelium of patients with cystic fibrosis
    • Knowles MR et al. A controlled study of adenoviral-vector-mediated gene transfer in the nasal epithelium of patients with cystic fibrosis. New Engl J Med 1995; 333: 823-831.
    • (1995) New Engl J Med , vol.333 , pp. 823-831
    • Knowles, M.R.1
  • 8
    • 0025647882 scopus 로고
    • Recombinant human DNase 1 reduces the viscosity of cystic fibrosis sputum
    • Shak S et al. Recombinant human DNase 1 reduces the viscosity of cystic fibrosis sputum. Proc Natl Acad Sci USA 1990; 87: 9188-9192.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 9188-9192
    • Shak, S.1
  • 9
    • 0028951077 scopus 로고
    • Aerosolized dornase alpha (rhDNase) for therapy of cystic fibrosis
    • Hodson ME. Aerosolized dornase alpha (rhDNase) for therapy of cystic fibrosis Am J Respir Crit Care Med 1995; 151: S70-S74.
    • (1995) Am J Respir Crit Care Med , vol.151
    • Hodson, M.E.1
  • 10
    • 0010564030 scopus 로고
    • Construction of plasmids that express E. Coli β-galactosidase in mammalian cells
    • MacGreggor GR, Caskey CT. Construction of plasmids that express E. Coli β-galactosidase in mammalian cells. Nucleic Acids Res 1989; 17: 2365-2369.
    • (1989) Nucleic Acids Res , vol.17 , pp. 2365-2369
    • MacGreggor, G.R.1    Caskey, C.T.2
  • 11
    • 0026094167 scopus 로고
    • A novel cationic lipid reagent for efficient transfection of mammalian cells
    • Gao X, Huang L. A novel cationic lipid reagent for efficient transfection of mammalian cells. Biochem Biophys Res Comm 1991; 179: 280-285.
    • (1991) Biochem Biophys Res Comm , vol.179 , pp. 280-285
    • Gao, X.1    Huang, L.2
  • 12
    • 0028902754 scopus 로고
    • Modulation of gene expression after replication deficient recombinant adenovirus-mediated gene transfer by the product of a second adenovirus vector
    • Hersh J, Crystal RG, Bewig B. Modulation of gene expression after replication deficient recombinant adenovirus-mediated gene transfer by the product of a second adenovirus vector. Gene Therapy 1995; 2: 124-131.
    • (1995) Gene Therapy , vol.2 , pp. 124-131
    • Hersh, J.1    Crystal, R.G.2    Bewig, B.3
  • 13
    • 0003579085 scopus 로고
    • The properties of the mucus gel layer in the gastrointestinal tract
    • Brostoff J. Challacombe SJ (eds). WB Saunders: London
    • Clamp JR. The properties of the mucus gel layer in the gastrointestinal tract. In: Brostoff J. Challacombe SJ (eds). Food Allergy and Intolerance. WB Saunders: London, 1987, pp 190-205.
    • (1987) Food Allergy and Intolerance , pp. 190-205
    • Clamp, J.R.1
  • 14
    • 0025802978 scopus 로고
    • Mucus glycoproteins from cystic fibrosis sputum. Macromolecular properties and structural 'architecture'
    • Thomton DJ, Sheehan JK, Lindgren H, Carstedt I. Mucus glycoproteins from cystic fibrosis sputum. Macromolecular properties and structural 'architecture'. Biochem J 1991; 276: 667-675
    • (1991) Biochem J , vol.276 , pp. 667-675
    • Thomton, D.J.1    Sheehan, J.K.2    Lindgren, H.3    Carstedt, I.4
  • 15
    • 0021988748 scopus 로고
    • - current status of the host-bacterium interaction
    • - current status of the host-bacterium interaction. J Infect Dis 1985; 151: 575-580.
    • (1985) J Infect Dis , vol.151 , pp. 575-580
    • Pier, G.G.1
  • 16
    • 0022797349 scopus 로고
    • Pseudomonas aeruginosa and cystic fibrosis: Unusual bacterial adaptation and pathogenesis
    • Govan JRW, Harris GS. Pseudomonas aeruginosa and cystic fibrosis: unusual bacterial adaptation and pathogenesis. Microbiol Sci 1986; 3: 302-308.
    • (1986) Microbiol Sci , vol.3 , pp. 302-308
    • Govan, J.R.W.1    Harris, G.S.2
  • 17
    • 6844255819 scopus 로고
    • The effect of Nacystelyn on the viscoelastic properties of mucus and frog palate transport rate
    • Marriot C, Ingham S, Pritchard K, Williams M. The effect of Nacystelyn on the viscoelastic properties of mucus and frog palate transport rate. Eur Resp J 1991; 4: 378s.
    • (1991) Eur Resp J , vol.4
    • Marriot, C.1    Ingham, S.2    Pritchard, K.3    Williams, M.4
  • 18
    • 0021447185 scopus 로고
    • In vitro effect of the slime of Pseudomonas aeruginosa on the function of human polymorphonuclear neutrophils
    • Laharrague PF et al. In vitro effect of the slime of Pseudomonas aeruginosa on the function of human polymorphonuclear neutrophils. Infect Immunol 1984; 44: 760-762.
    • (1984) Infect Immunol , vol.44 , pp. 760-762
    • Laharrague, P.F.1
  • 19
    • 0022004116 scopus 로고
    • The effect of Pseudomonas alginate on rat alveolar macrophage phagocytosis and bacterial opsonisation
    • Oliver AM, Weir DM. The effect of Pseudomonas alginate on rat alveolar macrophage phagocytosis and bacterial opsonisation. Clin Exp Immunol 1985; 59: 190-196.
    • (1985) Clin Exp Immunol , vol.59 , pp. 190-196
    • Oliver, A.M.1    Weir, D.M.2
  • 20
    • 0025203044 scopus 로고
    • In vitro immunosuppressive properties of the exopolysaccharide of mucoid strains of Pseudomonas aeruginosa
    • Mai GT, Seow WK, McCormack JG, Thong YH. In vitro immunosuppressive properties of the exopolysaccharide of mucoid strains of Pseudomonas aeruginosa. Int Arch Allergy Appl Immunol 1990; 92: 105-112.
    • (1990) Int Arch Allergy Appl Immunol , vol.92 , pp. 105-112
    • Mai, G.T.1    Seow, W.K.2    McCormack, J.G.3    Thong, Y.H.4
  • 21
    • 0021971601 scopus 로고
    • Role of Pseudomonas aeruginosa mucoid exopolysaccharide in the adherence to tracheal cells
    • Ramphal R, Pier GB. Role of Pseudomonas aeruginosa mucoid exopolysaccharide in the adherence to tracheal cells. Infect Immunol 1985; 47: 1-4.
    • (1985) Infect Immunol , vol.47 , pp. 1-4
    • Ramphal, R.1    Pier, G.B.2
  • 22
    • 0021799243 scopus 로고
    • Quantitation of adherence of and non-mucoid Pseudomonas aeruginosa to hamster tracheal cells
    • Marcus H, Baker NR. Quantitation of adherence of and non-mucoid Pseudomonas aeruginosa to hamster tracheal cells. Infect Immunol 1985; 47: 723-729.
    • (1985) Infect Immunol , vol.47 , pp. 723-729
    • Marcus, H.1    Baker, N.R.2
  • 23
    • 0023239490 scopus 로고
    • Characterization of the binding of Pseudomonas aeruginosa alginate to human epithelial cells
    • Doig P, Smith NR, Todd T, Irvin RT. Characterization of the binding of Pseudomonas aeruginosa alginate to human epithelial cells. Infect Immunol 1987; 55: 1517-1522.
    • (1987) Infect Immunol , vol.55 , pp. 1517-1522
    • Doig, P.1    Smith, N.R.2    Todd, T.3    Irvin, R.T.4
  • 24
    • 0026556379 scopus 로고
    • Enzymic degradation of alginates
    • Gacesa P. Enzymic degradation of alginates. Int J Biochem 1992; 24: 545-552.
    • (1992) Int J Biochem , vol.24 , pp. 545-552
    • Gacesa, P.1
  • 25
    • 0027379841 scopus 로고
    • Inhibition of adherence of mucoid Pseudomonas aeruginosa by alginase, specific monoclonal antibodies, and antibiotics
    • Mai GT et al. Inhibition of adherence of mucoid Pseudomonas aeruginosa by alginase, specific monoclonal antibodies, and antibiotics. Infect Immunol 1993; 61: 4338-4343.
    • (1993) Infect Immunol , vol.61 , pp. 4338-4343
    • Mai, G.T.1
  • 26
    • 0028674188 scopus 로고
    • Addition of a bacterial alginate lyase to purulent CF sputum in vitro can result in the disruption of alginate and modification of sputum viscoelasticity
    • Mrsny RJ et al. Addition of a bacterial alginate lyase to purulent CF sputum in vitro can result in the disruption of alginate and modification of sputum viscoelasticity. Pulin Pharmacol 1994; 7: 357-366.
    • (1994) Pulin Pharmacol , vol.7 , pp. 357-366
    • Mrsny, R.J.1
  • 27
    • 0001513063 scopus 로고
    • Composition of pulmonary secretions from patients with and without cystic fibrosis
    • Potter JL, Matthews LW, Lemm J, Spector JS. Composition of pulmonary secretions from patients with and without cystic fibrosis. Am J Dis Child 1960; 199: 493-495.
    • (1960) Am J Dis Child , vol.199 , pp. 493-495
    • Potter, J.L.1    Matthews, L.W.2    Lemm, J.3    Spector, J.S.4
  • 29
    • 0029099327 scopus 로고
    • DNA concentration and length in sputum of patients with cystic fibrosis during inhalation with recombinant human DNase
    • Brandt T, Breitenstein S, van der Hardt H, Tummler B. DNA concentration and length in sputum of patients with cystic fibrosis during inhalation with recombinant human DNase. Thorax 1995; 50: 880-882
    • (1995) Thorax , vol.50 , pp. 880-882
    • Brandt, T.1    Breitenstein, S.2    Van der Hardt, H.3    Tummler, B.4
  • 30
    • 0028072689 scopus 로고
    • New structures in complex formation between DNA and cationic liposomes visualised by freeze-fracture electron microscopy
    • Sternberg B, Sorgi F, Huang L New structures in complex formation between DNA and cationic liposomes visualised by freeze-fracture electron microscopy. FEBS Lett 1994; 336: 361-366.
    • (1994) FEBS Lett , vol.336 , pp. 361-366
    • Sternberg, B.1    Sorgi, F.2    Huang, L.3
  • 31
    • 0019351935 scopus 로고
    • SV-40 transformed simian cells support the replication of early SV40 mutants
    • Gluzman Y. SV-40 transformed simian cells support the replication of early SV40 mutants. Cell 1981; 23: 175-182.
    • (1981) Cell , vol.23 , pp. 175-182
    • Gluzman, Y.1
  • 32
    • 0027928745 scopus 로고
    • CFTR expression and chloride secretion in polarized immortal human bronchial epithelial cells
    • Cozens AL et al. CFTR expression and chloride secretion in polarized immortal human bronchial epithelial cells. Am J Respir Cell Mol Biol 1994; 10: 38-17.
    • (1994) Am J Respir Cell Mol Biol , vol.10 , pp. 38-117
    • Cozens, A.L.1
  • 33
    • 0026724465 scopus 로고
    • Characterisation of immortal cystic fibrosis tracheobronchial gland epithelial cells
    • Cozens AL et al. Characterisation of immortal cystic fibrosis tracheobronchial gland epithelial cells. Proc Natl Acad Sci USA 1992; 89: 5171-5175.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 5171-5175
    • Cozens, A.L.1
  • 34
    • 0028387979 scopus 로고
    • Gene therapy for cystic fibrosis in humans by liposome-mediated DNA transfer: The production of resources and the regulatory process
    • Caplen NJ et al. Gene therapy for cystic fibrosis in humans by liposome-mediated DNA transfer: the production of resources and the regulatory process Gene Therapy 1994; 2: 1-9.
    • (1994) Gene Therapy , vol.2 , pp. 1-9
    • Caplen, N.J.1
  • 35
    • 0028024919 scopus 로고
    • Enhanced gene delivery and mechanism studies with a novel series of cationic lipid formulations
    • Felgner JH et al. Enhanced gene delivery and mechanism studies with a novel series of cationic lipid formulations. J Biol Chem 1994; 269: 2530-2561.
    • (1994) J Biol Chem , vol.269 , pp. 2530-2561
    • Felgner, J.H.1
  • 36
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilising the principle of protein-dye binding
    • Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilising the principle of protein-dye binding. Anal Biochem 1976; 72: 248-254.
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 37
    • 0028109209 scopus 로고
    • Improving access to intestinal stem cells as a step toward intestinal gene transfer
    • Sandberg JW et al. Improving access to intestinal stem cells as a step toward intestinal gene transfer. Hum Gene Ther 1994; 5: 323-329.
    • (1994) Hum Gene Ther , vol.5 , pp. 323-329
    • Sandberg, J.W.1
  • 39
    • 0026878142 scopus 로고
    • Gene transfer in vivo with DNA-liposome complexes: Safety and acute toxicity in mice
    • Stewart MJ et al. Gene transfer in vivo with DNA-liposome complexes: safety and acute toxicity in mice. Hum Gene Ther 1992; 3: 267-275.
    • (1992) Hum Gene Ther , vol.3 , pp. 267-275
    • Stewart, M.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.