Wheat flour fortification with iron for reducing anaemia and improving iron status in populations

Cochrane Database of Systematic Reviews

Volumn 2020, Issue 7, 2020, Pages

  Field, Martha S ^a   Mithra, Prasanna ^b   Estevez, Diana ^c   Peña Rosas, Juan Pablo ^c  

^a Department of Molecular Biology and Genetics   (United States)

^b KASTURBA MEDICAL COLLEGE   (India)

^c WORLD HEALTH ORGANIZATION   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

EDETATE IRON; FERROUS FUMARATE; FERROUS SULFATE; FOLIC ACID; HEMOGLOBIN; IRON; MINERAL; RETINOL; RETINOL PALMITATE; TRACE ELEMENT; VITAMIN; ZINC; EDETIC ACID; FE(III)-EDTA; FERRIC ION; FERROUS ION; FUMARIC ACID DERIVATIVE; HEMOGLOBIN A;

ANEMIA; BISCUIT; BREAD; COGNITIVE DEVELOPMENT; DIETARY INTAKE; FORTIFIED FOOD; HEMOGLOBIN DETERMINATION; HUMAN; IRON DEFICIENCY; PATIENT COMPLIANCE; PREVALENCE; PRIORITY JOURNAL; REVIEW; RISK BENEFIT ANALYSIS; SYSTEMATIC REVIEW; THERAPY EFFECT; TREATMENT OUTCOME; WHEAT FLOUR; ADOLESCENT; ADULT; BLOOD; CHILD; FEMALE; FLOUR; INFANT; MALE; META ANALYSIS; MIDDLE AGED; PRESCHOOL CHILD; RANDOMIZED CONTROLLED TRIAL (TOPIC); WHEAT; YOUNG ADULT;

ADOLESCENT; ADULT; ANEMIA; CHILD; CHILD, PRESCHOOL; EDETIC ACID; FEMALE; FERRIC COMPOUNDS; FERROUS COMPOUNDS; FLOUR; FOOD, FORTIFIED; FUMARATES; HEMOGLOBIN A; HUMANS; INFANT; IRON; MALE; MICRONUTRIENTS; MIDDLE AGED; RANDOMIZED CONTROLLED TRIALS AS TOPIC; TRITICUM; YOUNG ADULT;

EID: 85088222581     PISSN: None     EISSN: 1469493X     Source Type: Journal    
DOI: 10.1002/14651858.CD011302.pub2     Document Type: Review

References (187)

1. Amalrajan V, Thankachan P, Selvam S, Kurpad A. Effect of wheat flour fortified with sodium iron EDTA on urinary zinc excretion in school-aged children. Food and Nutrition Bulletin 2012;33(3):177-9. x-wiley/crsRef/14168764
2. Barbosa TN, Taddei JA, Palma D, Ancona-Lopez F, Braga JA. Double-blind randomised controlled trial of rolls fortified with microencapsulated iron [Estudo duplo-cego randomizado controlado com pães fortificados com ferro microencapsulado]. Revista da Associacao Medica Brasileira 2012;58(1):118-24. x-wiley/crsRef/14168766
3. Biebinger R, Zimmermann MB, Al-Hooti SN, Al-Hamed N, Al-Salem E, Zafar T, et al. Efficacy of wheat-based biscuits fortified with microcapsules containing ferrous sulfate and potassium iodate or a new hydrogen-reduced elemental iron: a randomised, double-blind, controlled trial in Kuwaiti women. British Journal of Nutrition 2009;102(9):1362-9. x-wiley/crsRef/14168768
4. Cabalda AB, Tengco LW, Solon JAA, Sarol JN Jr, Rayco-Solon P, Solon FS. Efficacy of pandesal baked from wheat flour fortified with iron and vitamin A in improving the iron and anthropometric status of anemic schoolchildren in the Philippines. Journal of the American College of Nutrition 2009;28(5):591-600. x-wiley/crsRef/14168770
5. Cabalda AB, Tengco LW, Solon JAA, Sarol JN Jr, Rayco-Solon P, Solon FS. Wheat bread fortified with iron and vitamin A improved iron status of anemic schoolchildren. Annals of Nutrition and Metabolism 2009;55:239. x-wiley/crsRef/14168771
6. Dad F, Khan S, Habib I, Shah BR, Sohail M. Effect of iron fortified wheat flour consumption on the hemoglobin status of adolescent girls in district Buner. American Journal of Food Science and Health 2017;3(1):1-6. x-wiley/crsRef/14168773
7. Dad F. Regards and question on your study [personal communication]. Email to: JP Peña-Rosas 15 March 2017. x-wiley/crsRef/14168774
8. Muthayya S, Thankachan P, Hirve S, Amalrajan V, Thomas T, Lubree H, et al. Iron fortification of whole wheat flour reduces iron deficiency and iron deficiency anemia and increases body iron stores in Indian school-aged children. Journal of Nutrition 2012;142(11):1997-2003. x-wiley/crsRef/14168776
9. Nestel P, Nalubola R, Sivakaneshan R, Wickramasinghe A R, Atukorala S, Wickramanayake T, et al. The use of iron-fortified wheat flour to reduce anemia among the estate population in Sri Lanka. International Journal for Vitamin and Nutrition Research 2004;74(1):35-51. x-wiley/crsRef/14168778
10. Rahman AS, Ahmed T, Ahmed F, Alam MS, Wahed MA, Sack DA. Double-blind cluster randomised controlled trial of wheat flour chapatti fortified with micronutrients on the status of vitamin A and iron in school-aged children in rural Bangladesh. Maternal & Child Nutrition 2015;11(Suppl 4):120-31. x-wiley/crsRef/14168780
11. van Stuijvenberg ME, Smuts CM, Lombard CJ, Dhansay MA. Fortifying brown bread with sodium iron EDTA, ferrous fumarate, or electrolytic iron does not affect iron status in South African schoolchildren. Journal of Nutrition 2008;138(4):782-6. x-wiley/crsRef/14168782
12. Abreu LC. Impacto da fortificação das farinhas com ferro no controle da anemia em gestantes: estudo em um serviço público de saúde do município de São Bernardo do Campo. Dissertação (Mestrado em Nutrição em Saúde Pública). Sao Paulo: Faculdade de Saúde Pública, Universidade de São Paulo, 2009. x-wiley/crsRef/14168784
13. Al Rifai R, Nakamura K, Seino K. Decline in the prevalence of anaemia among children of pre-school age after implementation of wheat flour fortification with multiple micronutrients in Jordan. Public Health Nutrition 2016;19(8):1486-97. x-wiley/crsRef/14168786
14. Araújo CR, Uchimura TT, Fujimori E, Nishida FS, Veloso GB, Szarfarc SC. Hemoglobin levels and prevalence of anemia in pregnant women assisted in primary health care services, before and after fortification of flour. Revista Brasileira de Epidemiologia [Brazilian Journal of Epidemiology] 2013;16(2):535-45. x-wiley/crsRef/14168788
15. Assunção MC, Santos IS, Barros AJ, Gigante DP, Victoria CG. Effect of iron fortification of flour on anemia in preschool children in Pelotas Brazil. Revista de Saude Publica 2007;41(4):539-48. x-wiley/crsRef/14168790
16. Assunção MC, Santos IS. Effect of food fortification with iron on childhood anemia: a review study [Efeito da fortificação de alimentos com ferro sobre anemia em crianças: um estudo de revisão]. Caderno de Saude Publica 2007;23(2):269-81. x-wiley/crsRef/14168791
17. Biemi FD. Effectiveness of mandated folic acid and iron fortification of wheat flour on anemia in children of Ivory Coast. Thesis. http://scholarworks.gsu.edu/nutrition_theses/44/ (accessed 4 October 2016). Vol. Nutrition Theses. Atlanta: Georgia State University, 2013. x-wiley/crsRef/14168793
18. Bokhari F, Derbyshire EJ, Hickling D, Li W, Brennan CS. A randomized trial investigating an iron-rich bread as a prophylaxis against iron deficiency in pregnancy. International Journal of Food Sciences and Nutrition 2012;63(4):461-7. x-wiley/crsRef/14168795
19. Bothwell TH, Derman D, Bezwoda WR, Torrance JD, Charlton RW. Can iron fortification of flour cause damage to genetic susceptibles (idiopathic haemochromatosis and beta-thalassaemia major)? Human Genetics 1978;Supplement(1):131-7. x-wiley/crsRef/14168797
20. Bouhouch R R, El-Fadeli S, Andersson M, Aboussad A, Chabaa L, Zeder C, et al. Effects of wheat-flour biscuits fortified with iron and EDTA, alone and in combination, on blood lead concentration, iron status, and cognition in children: A double-blind randomized controlled trial. The American Journal of Clinical Nutrition 2016;104(5):1318-26. x-wiley/crsRef/14168799
21. Bromage S, Ganmaa D, Rich-Edwards JW, Rosner B, Bater J, Fawzi WW. Projected effectiveness of mandatory industrial fortification of wheat flour, milk, and edible oil with multiple micronutrients among Mongolian adults. PLOS One 2018;13(8)::e0201230. doi: 10.1371/journal.pone.0201230. eCollection 2018. x-wiley/crsRef/14168801
22. Brown KH, Engle-Stone R, Ndjebayi AO, Erhardt J, Nankap M. Vitamin A and iron status and intake of fortifiable foods among Cameroonian women and preschool child. FASEB Journal 2011;25:108.3. x-wiley/crsRef/14168803
23. Chavez JF, Gamero EG. Enrichment of precooked corn and wheat flour in Venezuela. A successful experience. Interciencia 1998;23(6):338-343. x-wiley/crsRef/14168805
24. Costa CA, Machado EH, Colli C, Latorre WC, Szarfarc SC. Anemia in pre-school children attending day care centers of São Paulo: perspectives of the wheat and maize flour fortification [Anemia em pré-escolares atendidos em creches de Sâo Paulo (SP): perspectivas decorrentes da fortificação das farinhas de trigo e de milho]. Nutrire Revista da Sociedade Brasileira de Alimentação e Nutrição 2009;34(1):59-74. x-wiley/crsRef/14168807
25. Costa CA. Concentração de hemoglobina e prevalência de anemia em pré-escolares atendidos em creches da rede pública do município de São Paulo: perspectivas frente à fortificação das farinhas com ferro (Hemoglobin concentration and prevalence of anemia in pre-school children attending public child day care centers in São Paulo: perspectives concerning flour fortification with iron). Vol. 1. Sao Paulo: Universidade de Sao Paulo, 2008. x-wiley/crsRef/14168808
26. Da Silva CL, Saunders C, Szarfarc SC, Fujimori E, Da Veiga GV. Anaemia in pregnant women before and after the mandatory fortification of wheat and corn flours with iron. Public Health Nutrition 2012;15(10):1802-9. x-wiley/crsRef/14168810
27. De Souza MD, Damasceno CVX, Szarfarc SC, Fujimori E, Araujo MAD, Moreira-Araujo RSD. Fortification of flours with iron and control of anemia in pregnant women in Teresina, Piaui, Brazil [Fortificação das farinhas com ferro e controle da anemia em gestantes de Teresina, Piauí, Brasil]. Revista De Nutricao - Brazilian Journal of Nutrition 2011;24(5):679-88. x-wiley/crsRef/14168812
28. de Vasconcelos P N, Cavalcanti D S, Leal L P, Osorio M M, Batista M. Time trends in anemia and associated factors in two age groups (6-23 and 24-59 months) in Pernambuco State, Brazil, 1997-2006. Cad. Saude Publica 2014;30(8):1777-87. x-wiley/crsRef/14168814
29. El Hamdouchi A, El Kari K, Rjimati EA, El Mzibri M, Mokhtar N, Aguenaou H. Does flour fortification with electrolytic elemental iron improve the prevalence of iron deficiency anaemia among women in childbearing age and preschool children in Morocco? Mediterranean Journal of Nutrition and Metabolism 2013;6(1):73-8. x-wiley/crsRef/14168816
30. El Hamdouchi A, El Kari K, Rjimati L, El Haloui N, El Mzibri M, Aquenaou H, et al. Impact of flour fortification with elemental iron on the prevalence of anaemia among preschool children in Morocco. Eastern Mediterranean Health Journal 2010;16(11):1148-52. x-wiley/crsRef/14168817
31. Elwood PC, Waters WE, Sweetnam P. The Hematinic effect of iron in flour. Clinical Science (London) 1971;40:31-7. x-wiley/crsRef/14168819
32. Engle-Stone R, Martin N, Ndjebayi AO, Allen LH, Shahab-Ferdows S, Hampel D, et al. Iron, zinc, folate, and vitamin B-12 status increased among women and children in Yaounde and Douala, Cameroon, 1 year after Introducing fortified wheat flour. The Journal of Nutrition 2017;147(7):1426-36. x-wiley/crsRef/14168821
33. Fallahi E, Kimiagar M, Valaei N, Abbasi S. Effect of fortified flour with ferrous sulfate alone and with Na(2)EDTA on iron deficiency anemia and serum zinc. Journal of Food Agriculture & Environment 2003;1(3&4):69-71. x-wiley/crsRef/14168823
34. Fujimori E, Szarfarc SCS, Sato APS. Impact of flours fortification with iron in anaemia control of pregnant women attended at Brazilian public health services. Annals of Nutrition and Metabolism 2009;55(1):298. x-wiley/crsRef/14168825
35. Fujimori E, Sato AP, Szarfarc SC, Veiga GV, Oliveira VA, Colli C, et al. Anemia in Brazilian pregnant women before and after flour fortification with iron [Anemia em gestantes brasileiras antes e após a fortificação das farinhas com ferro]. Revista de Saude Publica 2011;45(6):1027-35. x-wiley/crsRef/14168827
36. Giorgini E, Fisber M, De Paula RAC, Ferreira AMA, Valle J, Braga JAP. The use of sweet rolls fortified with iron bis-glycinate chelate in the prevention of iron deficiency anemia in preschool children. Archivos Latinoamericanos de Nutricion 2001;51(Supplement 1):48-53. x-wiley/crsRef/14168829
37. Granado FS, Augusto RA, Muniz PT, Cardoso MA, Action Study Team. Anaemia and iron deficiency between 2003 and 2007 in Amazonian children under 2 years of age: trends and associated factors. Public Health Nutrition 2013;16(10):1751-9. x-wiley/crsRef/14168831
38. Grimm KA, Sullivan KM, Alasfoor D, Parvanta I, Suleiman AJM, Kaur M, et al. Iron-fortified wheat flour and iron deficiency among women. Food and Nutrition Bulletin 2012;33(3):180-5. x-wiley/crsRef/14168833
39. Hallberg L, Rossanderhulthen L, Gramatkovski E. Iron fortification of flour with a complex ferric ortho-phosphate. American Journal of Clinical Nutrition 1989;50(1):129-35. x-wiley/crsRef/14168835
40. Hassanvand E, Daraei Garmekhany A. Effect of flour enrichment on anemia prevalence in Lorestan province and its probable inefficiency factors. Minerva Biotecnologica 2015;27(4):159-62. x-wiley/crsRef/14168837
41. Heijblom GS, Pacheco-Santos LM. Iron deficiency anemia in first grade students from public schools in a region of Brasília, DF [Anemia ferropriva em escolares da primeira série do ensino fundamental da rede pública de educação de uma região de Brasília, DF]. Revista Brasileira de Epidemiologia 2007;10(2):258-66. x-wiley/crsRef/14168839
42. Huang J, Sun J, Li WX, Wang LJ, Wang AX, Huo JS, et al. Efficacy of different iron fortificants in wheat flour in controlling iron deficiency. Biomedical and Environmental Sciences 2009;22(2):118-21. x-wiley/crsRef/14168841
43. Sun J, Huang J, Li W, Wang L, Wang A, Huo J, et al. Effects of wheat flour fortified with different iron fortificants on iron status and anemia prevalence in iron deficient anemic students in Northern China. Asia Pacific Journal of Clinical Nutrition 2007;16(1):116-21. x-wiley/crsRef/14168842
44. Hund L, Northrop-Clewes CA, Nazario R, Suleymanova D, Mirzoyan L, Irisova M, et al. A novel approach to evaluating the iron and folate status of women of reproductive age in Uzbekistan after 3 years of flour fortification with. PLos ONE Nov, 2013;8(11):e79726. x-wiley/crsRef/14168844
45. Huo J, Sun J, Huang J, Li W, Wang L, Selenje L, et al. The effectiveness of fortified flour on micro-nutrient status in rural female adults in China. Asia Pacific Journal of Clinical Nutrition 2011;20(1):118-24. x-wiley/crsRef/14168846
46. Huo J, Sun J, Huang J, Li W, Wang L, Selenje L, Gleason GR, Yu X. Effectiveness of fortified flour for enhancement of vitamin and mineral intakes and nutrition status in northwest Chinese villages. Food and Nutrition Bulletin 2012;33(2):161-8. x-wiley/crsRef/14168848
47. Imhoff-Kunsch B, Shakya I, Namohunu SAD, Pitaboe A, Wong P, Tsang BL, et al. Potential dietary contributions from rice and wheat flour fortification in the Solomon Islands: Results from the 2012-2013 Household Income and Expenditure Survey. Food and Nutrition Bulletin 2019;40(1):71-86. x-wiley/crsRef/14168850 [DOI: 10.1177/0379572118817179. Epub 2019 Jan 3.]
48. Kamien M, Woodhill JM, Nobile S, Cameron P, Rosevear P. Nutrition in the Australian aborigines--effects of the fortification of white flour. Australian & New Zealand Journal of Medicine 1975;5(2):123-33. x-wiley/crsRef/14168852
49. Kendrick K, Codling K, Muslimatun S, Pachon H. The contribution of wheat flour fortification to reducing anemia in Indonesia. European Journal of Nutrition & Food Safety 2015;5(5):446-447. x-wiley/crsRef/14168854
50. Pachon H, Kendrick K, Codling K, Muslimatun S. Analysis of the family life surveys in Indonesia: the contribution of wheat flour fortification to reducing anemia. FASEB Journal 2015;29(Suppl. 1):729.11. x-wiley/crsRef/14168855 [https://legacy-etd.library.emory.edu/view/record/pid/emory:fzgxj]
51. Layrisse M, Chaves JF, Mendez-Castellano H, Bosch V, Tropper E, Bastardo B, Gonzalez E. Early response to the effect of iron fortification in the Venezuelan population. American Journal of Clinical Nutrition 1996;64(6):903-7. x-wiley/crsRef/14168857
52. Layrisse M, Garcia-Casal MN, Mendez-Castellano H, Jimenez M, Olavarria CH, Chavez JF, et al. Impact of fortification of flours with iron to reduce the prevalence of anemia and iron deficiency among schoolchildren in Caracas, Venezuela: A follow-up. Food and Nutrition Bulletin 2002;23(4):384-9. x-wiley/crsRef/14168859
53. Malpeli A, Ferrari MG, Varea A, Falivene M, Etchegoyen G, Vojkovic M, et al. Short-term evaluation of the impact of a fortified food aid program on the micronutrient nutritional status of Argentinian pregnant women. Biological Trace Element Research 2013;155(2):176-83. x-wiley/crsRef/14168861
54. Martorell Reynaldo, Ascencio Melany, Tacsan Luis, Alfaro Thelma, Young Melissa F, Addo O Yaw, et al. Effectiveness evaluation of the food fortification program of Costa Rica: impact on anemia prevalence and hemoglobin concentrations in women and children. American Journal of Clinical Nutrition 2015;101(1):210-7. x-wiley/crsRef/14168863
55. Milman N, Byg K E, Ovesen L. Iron status in Danes 1994. II: Prevalence of iron deficiency and iron overload in 1319 Danish women aged 40-70 years. Influence of blood donation, alcohol intake and iron supplementation. Annals of Hematology 2000;79(11):612-21. x-wiley/crsRef/14168865
56. Milman N, Byg KE, Ovesen L, Kirchhoff M, Jurgensen KSL. Iron status in Danish women, 1984-1994: A cohort comparison of changes in iron stores and the prevalence of iron deficiency and iron overload. European Journal of Haematology 2003;71(1):51-61. x-wiley/crsRef/14168866
57. Milman N, Ovesen L, Byg K, Graudal N. Iron status in Danes updated 1994. I: prevalence of iron deficiency and iron overload in 1332 men aged 40-70 years. Influence Of blood donation, alcohol intake, and iron supplementation. Annals of Hematology 1999;78(9):393-400. x-wiley/crsRef/14168867
58. Milman N, Pedersen AN, Ovesen L, Schroll M. Iron status in 358 apparently healthy 80-year-old Danish men and women: relation to food composition and dietary and supplemental iron intake. Annals of Hematology 2004;83(7):423-9. x-wiley/crsRef/14168868
59. Modjadji SEP, Alberts M, Mamabolo RL. Folate and iron status of South African non-pregnant rural women of childbearing, age, before and after fortification of foods. South African Journal of Clinical Nutrition 2007;20(3):89-93. x-wiley/crsRef/14168870
60. Mwangi MN, Roth JM, Smit MR, Trijsburg L, Mwangi AM et al. Effect of daily antenatal iron supplementation on plasmodium Infection in Kenyan women: a randomized clinical trial. JAMA 2015;314(10):1009-20. x-wiley/crsRef/14168872
61. Natvig H, Vellar OD. Iron fortified bread a long term controlled therapeutic community based experiment with ferrous sulfate enriched flour. Acta Medica Scandinavica 1973;194(5):463-71. x-wiley/crsRef/14168874
62. Osler M, Milman N, Heitmann BL. Consequences of removing iron fortification of flour on iron status among Danish adults: Some longitudinal observations between 1987 and 1994. Preventive Medicine 1999;29(1):32-6. x-wiley/crsRef/14168876
63. Papathakis PC, Pearson KE. Food fortification improves the intake of all fortified nutrients, but fails to meet the estimated dietary requirements for vitamins A and B-6, riboflavin and zinc, in lactating South African women. Public Health Nutrition 2012;15(10):1810-7. x-wiley/crsRef/14168878
64. Pouraram H, Elmadfa I, Siassi F, Dorosty Motlagh A, Heshmat R, Abtahi M. Oxidative stress among non-anemic adults following flour fortification with iron: baseline data. Annals of Nutrition & Metabolism 2010;56(4):283-7. x-wiley/crsRef/14168880
65. Pouraram H, Elmadfa I, Dorosty AR, Abtahi M, Neyestani TR, Sadeghian S. Long-term consequences of iron-fortified flour consumption in nonanemic men. Annals of Nutrition & Metabolism 2012;60(2):115-21. x-wiley/crsRef/14168882
66. Rohner F, Northrop-Clewes C, Raso G, Ake O, Tschannen A, Laillou A, et al. Effect of a fortified oil and flour program in Cote d'Ivoire on micronutrient status of pre-school children and women. In: IUNS 20 International Congress of Nutrition. 2013. x-wiley/crsRef/14168884
67. Sadighi J, Mohammad K, Sheikholeslam R, Amirkhani MA, Torabi P, Salehi F, Abdolahi Z. Anaemia control: Lessons from the flour fortification programme. Public Health Dec 2009;123(12):794-9. x-wiley/crsRef/14168886
68. Sadighi J, Sheikholeslam R, Mohammad K, Pouraram H, Abdollahi Z, Samadpour K, et al. Flour fortification with iron: a mid-term evaluation. Public Health (Elsevier) 2008;122(3):313-21. x-wiley/crsRef/14168887
69. Sato APS, Fujimori E, Szarfarc SC, Araujo CRMA, Queiroz VAD, Moreira-Araujo RSR, et al. Anaemia in pregnant women assisted by public healthcare services of the five Brazilian regions before and after the policy of fortification of flours with iron. Journal of Epidemiology & Community Health 2011;65(1):A376. x-wiley/crsRef/14168889
70. Sato APS, Fujimori E, Szarfarc SC, Sato JR, Bonadio IC. Prevalence of anemia in pregnant and iron fortification of flours [Prevalência de anemia em gestantes e a fortificação de farinhas com ferro]. Texto & Contexto Enfermagen 2008;17(3):474-81. x-wiley/crsRef/14168890
71. Sato APS, Fujimori E, Szarfarc SC. Hemoglobin level in pregnant women assisted by public prenatal services in the five regions of Brazil. European Journal of Epidemiology 2012;27:S126-S126. x-wiley/crsRef/14168891
72. Sato APS, Porto E, Brunken GS, Fujimori E, Leone C, Szarfarc, et al. Anemia and hemoglobin levels in pregnant women in Cuiabá, Mato Grosso, Brazil, before and after the fortification of meal with iron and folic acid, 2003-2006 [Anemia e nível de hemoglobina em gestantes de Cuiabá, Mato Grosso, Brasil, antes e após a fortificação compulsória de farinhas com ferro e ácido fólico, 2003-2006]. Epidemiologia e Serviços de Saúde 2015;24(3):453-64. x-wiley/crsRef/14168893
73. Simmons WK, Sinha DP. Reduction in anaemia in pregnant women in three Caribbean countries. possible results of different types of interventions. Ecology of Food & Nutrition 1994;32(3-4):149-55. x-wiley/crsRef/14168895
74. Sjoberg A, Hulthen L. Comparison of food habits, iron intake and iron status in adolescents before and after the withdrawal of the general iron fortification in Sweden. European Journal of Clinical Nutrition 2015;69(4):494-500. x-wiley/crsRef/14168897
75. Stuetz W, Carrara V, McGready R, Lee S, Erhardt J, Breuer J, et al. Micronutrient status in lactating mothers before and after introduction of fortified flour: cross-sectional surveys in Maela refugee camp. European Journal of Nutrition 2012;51(4):425-34. x-wiley/crsRef/14168899
76. Sun J, Huo J, Li W, Wang L, et al. Observation on effectiveness of fortified flour on nutrition status improvement of poor area women in Weichang County of Hebei Province in China. Wei sheng yan jiu - Journal of hygiene research 2008;37(2):199-202. x-wiley/crsRef/14168901
77. Tazhibayev S, Solmatova O, Ganiyeva G, Khairov K, Ospanova F, Oyunchimeg D, Suleimanova D, Scrimshaw N. Evaluation of the potential effectiveness of wheat flour and salt fortification programs in five Central Asian countries and Mongolia, 2002-2007. Food Nutr Bull 2008 Dec;29(4):255-65. x-wiley/crsRef/14168903
78. Varea A, Malpeli A, Etchegoyen G, Vojkovic M, Disalvo L, Apezteguia M, et al. Short-term evaluation of the impact of a food program on the micronutrient nutritional status of Argentinean children under the age of six. Biological Trace Element Research 2011;143(3):1337-48. x-wiley/crsRef/14168905
79. Varea A, Malpeli A, Disalvo L, Apezteguia M, Falivene M, Ferrari G, et al. Evaluation of the impact of a food program on the micronutrient nutritional status of Argentinean lactating mothers. Biological Trace Element Research 2012;150(1-3):103-8. x-wiley/crsRef/14168907
80. Zavaleta N, Abrams S, Lonnerdal B. Effect of wheat flour fortification with iron and without zinc, vitamin A and folic acid on serum copper in Peruvian infants. In: Latin American Society for Pediatric Research. Vol. 55. 2004:530. x-wiley/crsRef/14168909
81. Zimmermann MB, Winichiagoon P, Gowachirapant S, Hess SY, Harrington M, Chavasit V, et al. Comparison of the efficacy of wheat-based snacks fortified with ferrous sulfate, electrolytic iron, or hydrogen-reduced elemental iron: randomized, double-blind, controlled trial in Thai women. American Journal of Clinical Nutrition 2005;82(6):1276-82. x-wiley/crsRef/14168911
82. Zimmermann M. Iron fortification trial using NaFeEDTA in iron deficient lead-exposed children. International Clinical Trials Registry Platform unpublished. x-wiley/crsRef/14168913
83. Arcot J. Effect of nutrition-improved wheat-based food on the health of primary school children aged 6-12 years in Morobe province. https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?ACTRN=12616001271493 2016. x-wiley/crsRef/14168915
84. Tetanye E. Efficacy of an iron fortified wheat flour for the correction and the prevention of iron deficiency anaemia of children in Salapoumbe. https://pactr.samrc.ac.za/TrialDisplay.aspx?TrialID=3069 2018. x-wiley/crsRef/14168917
85. Geoffrey Adams, Martin C Gulliford, Obioha C Ukoumunne, Sandra Eldridge, Susan Chinn, Michael J Campbell. Patterns of intra-cluster correlation from primary care research to inform study design and analysis. Journal of Clinical Epidemiology 2004;57:785-794.
86. Andrews NC. Iron metabolism: Iron deficiency and iron overload. Annual Review of Genomics and Human Genetics 2000;1:75-98.
87. Balshem H, Helfanda M, Schünemann HJ, Oxmand AD, Kunze R, Brozek J, et al. GRADE guidelines: rating the quality of evidence: introduction. Journal of Clinical Epidemiology 2011;64(4):401-6.
88. Barkely JS, Wheeler KS, Pachon H. Anaemia prevalence may be reduced among countries that fortify flour. British Journal of Nutrition 2015;114:265-273.
89. Beard JL, Murray-Kolb LE, Rosales FJ, Solomons NW, Angelilli ML. Interpretation of serum ferritin concentrations as indicators of total-body iron stores in survey populations: the role of biomarkers for the acute phase response. American Journal of Clinical Nutrition 2006;84(6):1498-505.
90. Borenstein M, Hedges LV, Higgins JPT, Rothstein HR. Introduction to Meta-Analysis. 1 edition. Oxford: Wiley, 2009. [DOI: 978-0470057247]
91. Camaschella C. New insights into iron deficiency and iron deficiency an emia. Blood Reviews 2017;31:225-233.
92. Catdezzu P. Sourdough breads. In: Preedy VR, Watson RR, Patel VB, editors(s). Flour and breads and their fortification in health and disease prevention. First edition. London: Elsevier, 2011:37-46.
93. Centeno Tablante E, Pachón H, Guetterman HM, Finkelstein JL. Fortification of wheat and maize flour with folic acid for population health outcomes. Cochrane Database of Systematic Reviews 2019, Issue 7. [DOI: 10.1002/14651858.CD012150.pub2]
94. Chaparro CM and Suchdev PS. Anemia epidemiology, pathophysiology, and etiology in low- and middle-income countries. Annals of the New York Academy of Sciences 2019;1450:15-31.
95. Cochrane Effective Practice and Organisation of Care Group. Effective Practice and Organisation of Care (EPOC). EPOC Resources for review authors. Suggested risk of bias criteria for EPOC reviews. Oslo: Norwegian Knowledge Centre for the Health Services; 2013. Available at: http://epocoslo.cochrane.org/epoc-specific-resources-review-authors.
96. Cochrane Public Health Group. Guide for developing a Cochrane Protocol. Last updated: 24 November 2011. Available from http://ph.cochrane.org/sites/ph.cochrane.org/files/uploads/Guide%20for%20PH%20protocol_Nov%202011_final%20for%20website.pdf.
97. Codex Alimentarius. Codex standard for durum wheat semolina and durum wheat flour. Codex Standard 178-1991. Adopted 1991. Revision 1995. Available from http://www.codexalimentarius.org/input/download/standards/60/CXS_178e.pdf.
98. Codex Alimentarius. Codex standard for wheat flour. Codex Standard 152-1985. Adopted 1985. Revision 1995. Available from http://www.codexalimentarius.org/input/download/standards/50/CXS_152e.pdf.
99. Cook JD. Defining optimal body iron. Proceedings of the Nutrition Society 1999;58(2):489-95.
100. Cook JD, Flowers CH, Skikne BS. The quantitative assessment of body iron. Blood 2003;101(9):3359-64.
101. Veritas Health Innovation Covidence [Covidence]. Covidence systematic review software, Version Accessed 24 July 2018. Melbourne, Australia: Veritas Health Innovation, 2018.Available at www.covidence.org.
102. Dallman PR. Biochemical basis for the manifestations of iron deficiency. Annual Review of Nutrition 1986;6:13-40.
103. Darnton-Hill I, Mora JO, Weinstein H, Wilbur S, Nalubola PR. Iron and folate fortification in the Americas to prevent and control micronutrient malnutrition: an analysis. Nutrition Reviews 1999;57(1):25-31.
104. Dary O. Lessons learned with iron fortification in Central America. Nutrition Reviews 2002;60(7):S30-3.
105. Das JK, Salam RA, Lassi ZS, Bhutta ZA. Food fortification with calcium and vitamin D: impact on health outcomes. Cochrane Database of Systematic Reviews 2012, Issue 11. [DOI: 10.1002/14651858.CD010201]
106. Das JK, Salam RA, Kumar R, Bhutta ZA. Micronutrient fortification of food and its impact on woman and child health: a systematic review. Systematic Reviews 2013;2:67-93. [DOI: doi:10.1186/2046-4053-2-67.]
107. Das JK, Salam RA, Mahmood SB, Moin A, Kumar R, Mukhtar K, et al. Food fortification with multiple micronutrients: impact on health outcomes in general population. Cochrane Database of Systematic Reviews 2019, Issue 12. [DOI: 10.1002/14651858.CD011400.pub2]
108. De-Regil LM, Peña-Rosas JP, Flores-Ayala R, del Socorro Jefferds ME. Development and use of the generic WHO/CDC logic model for vitamin and mineral interventions in public health programmes. Public Health Nutrition 2014;17(3):634-9.
109. Elhakim N, Laillou A, El Nakeeb A, Yacoub R, Shehata M. Fortifying baladi bread in Egypt: reaching more than 50 million people through the subsidy program. Food and Nutrition Bulletin 2012;33(4 Suppl):S260-71.
110. Enghiad A, Ufer D, Countryman AM, Thilmany DD. An Overview of Global Wheat Market Fundamentals in an Era of Climate Concerns. International Journal of Agronomy 2017;2017:3931897. [DOI: https://doi.org/10.1155/2017/3931897]
111. Food and Agriculture Organization of the United Nations. Wheat Flour. Rome: Food and Agriculture Organization of the United Nations, 2009.
112. Food and Agriculture Organization of the United Nations. FAO Statistical Yearbook 2013. World food and agriculture. Available from http://www.fao.org/docrep/018/i3107e/i3107e00.htm.
113. Food and Agriculture Organization of the United Nations. FAO Cereal Supply and Demand Brief. Available from: http://www.fao.org/worldfoodsituation/csdb/en/ May 12, 2019. [http://www.fao.org/worldfoodsituation/csdb/en/; accessed December 2019]
114. Food and Agriculture Organization of the United Nations. Food Price Monitoring and Analysis. Available from: http://www.fao.org/giews/food-prices/international-prices/detail/en/c/1254992/ October 12, 2019. [http://www.fao.org/giews/food-prices/international-prices/detail/en/c/1254992/; accessed December 2019]
115. Food and Agriculture Organization of the United Nations and CAB International. Combating Micronutrient Deficiencies:Food-based Approaches. 2011. Edited by Brian Thompson and Leslie Amoroso. Available from http://www.fao.org/docrep/013/am027e/am027e00.htm.
116. Food Fortification Initiative. Global Progress. 2014. http://www.ffinetwork.org/global_progress/ (accessed 31 July 2014).
117. Food Fortification Initiative. Say hello to a fortified future. 2016 Year In Review 2017.
118. Finch CA, Monsen ER. Iron nutrition and the fortification of food with iron. JAMA 1972;219(11):1462-5.
119. Ganz T. Anemia of Inflammation. The New England Journal of Medicine 2019;381:1148-1157.
120. Garcia-Casal MN, Peña-Rosas JP, De-Regil LM, Gwirtz JA, Pasricha SR. Fortification of maize flour with iron for controlling anaemia and iron deficiency in populations. Cochrane Database of Systematic Reviews 2018, Issue 12. [DOI: 10.1002/14651858.CD010187.pub2]
121. Garcia-Casal MN, Pasricha SR, Martinez RX, Lopez-Perez L, Peña-Rosas JP. Are current serum and plasma ferritin cut-offs for iron deficiency and overload accurate and reflecting iron status? a systematic review. Archives of Medical Research 2018;49(6):405-417.
122. Garcia-Casal MN, Peña-Rosas JP, Urrechaga E, Escanero JF, Huo J, Martinez RX, et al. Performance and comparability of laboratory methods for measuring ferritin concentrations in human serum or plasma: a systematic review and meta-analysis. PloS One 2018;13(5):e0196576.
123. Garcia-Casal MN, Pasricha S, Sharma AJ, Pena-Rosas JP. Use and interpretation of hemoglobin concentrations for assessing anemia status in individuals and populations: results from a WHO technical meeting. Annals of the New York Academy of Sciences 2019;1450:5-14.
124. Gera T, Sachdev HS, Boy E. Effect of iron-fortified foods on hematologic and biological outcomes: systematic review of randomized controlled trials. American Journal of Clinical Nutrition 2012;96(2):309-24.
125. Gibson RS. Principles of Nutritional Assessment. 2 edition. New York: Oxford University Press, 2005. [DOI: 978-0195171693]
126. McMaster University GRADEpro GDT:GRADEpro Guideline Development Tool. McMaster University, 2015 (developed by Evidence Prime, Inc).Available from gradepro.org.
127. Gulliford MC, Ukoumunne OC, Chinn S. Components of variance and intraclass correlations for the design of community-based surveys and intervention studies: data from the health survey for england. American Journal of Epidemiology 1999;149(9):876-883.
128. Higgins JPT, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, Welch VA (editors). Cochrane Handbook for Systematic Reviews of Interventions. 2nd Edition. Chichester (UK): John Wiley & Sons, 2019.
129. Hombali AS, Solon JA, Venkatesh BT, Nair NS, Peña-Rosas JP. Fortification of staple foods with vitamin A for vitamin A deficiency. Cochrane Database of Systematic Reviews 2019, Issue 5. [DOI: 10.1002/14651858.CD010068.pub2]
130. Horton S, Ross J. The economics of iron deficiency. Food Policy 2007;32(1):141-3.
131. Hurrell RF, Reddy MB, Burri J, Cook JD. An evaluation of EDTA compounds for iron fortification of cereal-based foods. British Journal of Nutrition 2000;84(6):903-10.
132. Hurrell R, Ranum P, de Pee S, Biebinger R, Hulthen L, Johnson Q, et al. Revised recommendations for the iron fortification of wheat flour and an evaluation of the expected impact of current national wheat flour fortification programs. Food and Nutrition Bulletin 2010;31(1 Suppl):S7-21.
133. Indrani D, Rao VG. South Indian parotta: an unleavened flat bread. In: Preedy VR, Ross Watson R, Patel VB, editors(s). Flour and breads and their fortification in health and disease prevention. First edition. London: Elsevier, 2011:27-36.
134. Khan KS. WHO analysis of causes of maternal death: a systematic review. Lancet 2007;367(9516):1066-74.
135. Kumar V, Sinha AK, Makkar HPS, Becker K. Dietary roles of phytate and phytase in human nutrition: A review. Food Chemistry 2010;120(4):945-59.
136. Langendam MW, Akl EA, Dahm P, Glasziou P, Guyatt G, Schünemann HJ. Assessing and presenting summaries of evidence in Cochrane Reviews. Systematic Reviews 2013;2:81.
137. Liberati A, Altman DG, Tetzlaff J, Mulrow C, Gøtzsche PC, Ioannidis JP, et al. The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. Annals of Internal Medicine 2009;151(4):W6594.
138. Lulla RR, Thompson AA, Liem RI. Elevated soluble transferrin receptor levels reflect increased erythropoietic drive rather than iron deficiency in pediatric sickle cell disease. Pediatric Blood & Cancer 2010;55(1):141-4. [DOI: 10.1002/pbc.22471] [PMID: 20486179]
139. Lynch S. Iron metabolism. In: Klaus Kraemer, Michael B Zimmermann, editors(s). Nutritional Anemia. Basel: SIGHT AND LIFE Press, 2007:59-76.
140. Lynch S. The rationale for selecting and standardizing iron status indicators. In: World Health Organization. Report: Priorities in the assessment of vitamin A and iron status in populations, Panama City, Panama, 15-17 September 2010. Geneva, World Health Organization, 2012. Available from http://www.who.int/nutrition/publications/micronutrients/background_paper3_report_assessment_vitAandIron_status.pdf.
141. Lynch S, Pfeiffer CM, Georgieff MK, Brittenham G, Fairweather-Tait S, Hurrell RF, McArdle HJ, and Raiten DJ. Biomarkers of Nutrition for Development (BOND)--Iron Review. The Journal of Nutrition 2017;148:1001S-1067S.
142. Mannar V, Gallego EB. Iron fortification: country level experiences and lessons learned. Journal of Nutrition 2002;132(4 Suppl):856S-8S.
143. Nestel P, Nalubola R, Sivakaneshan R, Wickramasinghe AR, Atukorala S, Wickramanayake T. The use of iron-fortified wheat flour to reduce anemia among the estate population in Sri Lanka. International Journal for Vitamin and Nutrition Research 2004;74(1):35-51.
144. Neufeld LM, Baker S, Garrett GS, Haddad H. Coverage and utilization in food fortification programs: critical and neglected areas of evaluation. Journal of Nutrition 2017;147(5):1015S–1019S.
145. O'Neill J, Tabish H, Welch V, Petticrew M, Pottie K, Clarke M, et al. Applying an equity lens to interventions: using PROGRESS to ensure consideration of socially stratifying factors to illuminate inequities in health. Journal of Clinical Epidemiology 2013;67:56-64.
146. Olaoye OA, Ade-Omowaye BIO. Composite flours and breads: potential of local crops in developing countries. In: Preedy VR, Watson RR, Patel VB, editors(s). Flour and breads and their fortification in health and disease prevention. First edition. London: Elsevier, 2011:183-192.
147. Oliver S, Kavanagh J, Caird J, Lorenc T, Oliver K, Harden A, Thomas J, Greaves A, Oakley A. Health promotion, inequalities and young people’s health: a systematic review of research [Health promotion, inequalities and young people’s health: a systematic review of research]. London: EPPI-Centre, Social Science Research Unit, Institute of Education, University of London. 2008;https://eppi.ioe.ac.uk/cms/Default.aspx?tabid=2410(https://eppi.ioe.ac.uk/cms/Default.aspx?tabid=2410):https://eppi.ioe.ac.uk/cms/Default.aspx?tabid=2410.
148. Osorio MM. Determinant factors of anemia in children. Jornal de Pediatria 2002;78(4):269-78.
149. Pachon H, Spohrer R, Mei Z, Serdula MK. Evidence of the effectiveness of flour fortification programs on iron status and anemia: a systematic review. Nutrition Reviews 2015;73(11):780-95.
150. Pasricha SR, De-Regil LM, Garcia-Casal MN, Burford BJ, Gwirtz JA, Peña-Rosas JP. Fortification of maize flour with iron for preventing anaemia and iron deficiency in populations. Cochrane Database of Systematic Reviews 2012, Issue 11. [DOI: 10.1002/14651858.CD010187]
151. Peña-Rosas JP, Mithra P, Unnikrishnan B, Kumar N, De-Regil LM, Nair NS, et al. Fortification of rice with vitamins and minerals for addressing micronutrient malnutrition. Cochrane Database of Systematic Reviews 2019, Issue 10. [DOI: 10.1002/14651858.CD009902.pub2]
152. Phiri KS, Calis JC, Kachala D, Borgstein E, Waluza J, Bates I, et al. Improved method for assessing iron stores in the bone marrow. Journal of Clinical Pathology 2009;62(8):685-9. [DOI: 10.1136/jcp.2009.064451] [PMID: 19638538]
153. Prentice AM, Ghattas H, Doherty C, Cox SE. Iron metabolism and malaria. Food and Nutrition Bulletin 2007;28(4 Suppl):S524-39.
154. The Cochrane Collaboration Review Manager (RevMan). Version 5.4. The Cochrane Collaboration, 2020.
155. Rosell CM. The science of doughs and bread quality. In: Preedy VR, Watson RR, Patel VB, editors(s). Flour and breads and their fortification in health and disease prevention. First edition. London: Elsevier, 2011:3-14.
156. Jila Sadighi, Katayoun Jahangiri, Azita Goshtasebi, Rahele Rostami. Effectiveness of flour fortification with iron on anemia and iron deficiency: a systematic review. Journal of the Iranian Institute for Health Sciences Research 2015;3:269-296.
157. Jila Sadighi, Saharnaz Nedjat, Rahele Rostami. Effect of flour fortification with iron on biochemical indicators of anemia and iron deficiency: Meta-analysis of interventional studies [Effect of flour fortification with iron on biochemical indicators of anemia and iron deficiency: Meta-analysis of interventional studies]. Payesh Health Monitor 2017;16(6):677-713.
158. Sadighi J, Nedjat S, Rostami R. Systematic review and meta-analysis of the effect of iron-fortified flour on iron status of populations worldwide [Systematic review and meta-analysis of the effect of iron-fortified flour on iron status of populations worldwide]. Public health nutrition 2019;-:1-20. [DOI: 10.1017/S1368980019002179] [PMID: https://www.ncbi.nlm.nih.gov/pubmed/?term=10.1017%2FS1368980019002179]
159. Santos JAR, Christoforou A, Trieu K, McKenzie BL, Downs S, Billot L, et al. Iodine fortification of foods and condiments, other than salt, for preventing iodine deficiency disorders. Cochrane Database of Systematic Reviews 2019, Issue 2. [DOI: 10.1002/14651858.CD010734.pub2]
160. Sazawal S, Black RE, Ramsan M, Chwaya HM, Stoltzfus RJ, Dutta A, et al. Effects of routine prophylactic supplementation with iron and folic acid on admission to hospital and mortality in preschool children in a high malaria transmission setting: community-based, randomised, placebo-controlled trial. Lancet 2006;367(9505):133-43.
161. Schnall SF, Berliner N, Duffy TP, Benz EJ Jr. Approach to the adult and child with anemia. In: Hoffman R, Benz EJ Jr, Shattil SJ, Furie B, Cohen HJ, Silberstein LE, McGlave P, editors(s). Hematology: basic principles and practice. 3rd edition. Philadelphia: Churchill Livingstone, 2000.
162. Shah D, Sachdev HS, Gera T, De-Regil LM, Peña-Rosas JP. Fortification of staple foods with zinc for improving zinc status and other health outcomes in the general population. Cochrane Database of Systematic Reviews 2016, Issue 6. [DOI: 10.1002/14651858.CD010697.pub2]
163. Sousa L, Oliviera MM, Pessoa MTC, Barbosa LA. Iron overload: Effects on cellular biochemistry. Clinical Chimica Acta 2019;In press:online ahead of print. [DOI: 10.1016/j.cca.2019.11.029]
164. Spottiswoode N, Fried M, Drakesmith H, Duffy PE. Implications of malaria on iron deficiency control strategies. Advances in Nutrition 2012;3(4):570-578.
165. Stevens GA, Finucane MM, De-Regil LM, Paciorek CJ, Flaxman SR, Branca F, et al. Global, regional, and national trends in haemoglobin concentration and prevalence of total and severe anaemia in children and pregnant and non-pregnant women for 1995-2011: a systematic analysis of population-representative data. Lancet Global Health 2013;1(1):e16-25.
166. Stoltzfus RJ and Klemm R. Research, policy, and programmatic considerations from the Biomarkers Reflecting Inflammation and Nutritional Determinants (BRINDA) project. American Journal of Clinical Nutrition 2017;106:428S-434S.
167. Thurnham DI, McCabe GP. Influence of infection and inflammation on biomarkers of nutritional status with an emphasis on vitamin A and iron. In: World Health Organization. Report: Priorities in the assessment of vitamin A and iron status in populations, Panama City, Panama, 15-17 September 2010. Geneva, World Health Organization, 2012. Available from http://www.who.int/nutrition/publications/micronutrients/background_paper4_report_assessment_vitAandIron_status.pdf.
168. Umbreit J. Iron deficiency: a concise review. American Journal of Hematology 2005;78(3):225-31.
169. UNICEF Regional Office for Central and Eastern Europe and the Commonwealth of Independent States (CEE/CIS). The "Day of Three Laws" in Kyrgyzstan. 2009. Available from http://www.unicef.org/ceecis/media_11364.html.
170. Van Der Borght A, Goesaert H, Veraverbeke WS, Delcour JA. Fractionation of wheat and wheat flour into starch and gluten: overview of the main processes and the factors involved. Journal of Cereal Science 2005;41(3):221-37.
171. Verhoef H, West CE, Ndeto P, Burema J, Beguin Y, Kok FJ. Serum transferrin receptor concentration indicates increased erythropoiesis in Kenyan children with asymptomatic malaria. American Journal of Clinical Nutrition 2001;74(6):767-75. [PMID: 11722958]
172. Weiss G, Goodnough LT. Anemia of chronic disease. New England Journal of Medicine 2005;352(10):1011-23.
173. World Health Organization. Recommendations on wheat and maize flour fortification. Meeting report: Interim consensus statement. 2009. WHO reference number:WHO/NMH/NHD/MNM/09.1. Available from http://www.who.int/nutrition/publications/micronutrients/wheat_maize_fortification/en/.
174. World Health Organization. Haemoglobin concentrations for the diagnosis of anaemia and assessment of severity. 2011. WHO reference number:WHO/NMH/NHD/MNM/11.1. Available from http://www.who.int/vmnis/indicators/haemoglobin/en/.
175. World Health Organization. Serum ferritin concentrations for the assessment of iron status and iron deficiency in populations. 2011. WHO reference number:WHO/NMH/NHD/MNM/11.2. Available from http://www.who.int/vmnis/indicators/ferritin/en/.
176. World Health Organization. WHO/CDC logic model for micronutrient interventions in public health. 2011. WHO reference number:WHO/NMH/NHD/MNM/11.5. Available from http://www.who.int/vmnis/toolkit/logic_model/en/.
177. World Health Organization. Nutritional anaemias: tools for effective prevention and control. 2017: World Health Organization, 2017.
178. World Health Organization. World health statistics 2018: monitoring health for the SDGs, sustainable development goals. https://www.who.int/gho/publications/world_health_statistics/2018/en/ edition. Vol. -. Geneva,Switzerland: World Health Organization, 2018.
179. World Health Organization. Essential nutrition actions: mainstreaming nutrition through the life-course. Geneva: World Health Organization, 2019.
180. World Health Organization. Data. Global Health Observatory (https://www.who.int/gho/en/, accessed 11 July 2019).
181. World Health Organization. WHO guideline on use of ferritin concentrations to assess iron status in populations. Geneva: World Health Organization, 2020.
182. Joint World Health Organization/Centers for Disease Control and Prevention Technical Consultation on the Assessment of Iron Status at the Population Level (‎‎‎‎‎‎‎‎‎‎2004: Geneva, Switzerland)‎‎‎‎‎‎‎‎‎‎. Assessing the iron status of populations: including literature reviews: report of a Joint World Health Organization/Centers for Disease Control and Prevention Technical Consultation on the Assessment of Iron Status at the Population Level, Geneva, Switzerland, 6-8 April 2004, 2nd ed. World Health Organization. https://apps.who.int/iris/handle/10665/75368 2007;1(1):108 p.
183. World Health Organization, Food and Agricultural Organization of the United Nations. Guidelines on food fortification with micronutrients. Editors: Lindsay Allen, Bruno de Benoist, Omar Dary, Richard Hurrell. 2006. ISBN: 92 4 159401 2. Available from http://www.who.int/nutrition/publications/micronutrients/9241594012/en/.
184. Wieringa FT, Dijkhuizen MA, West CE, Northrop-Clewes CA, Muhilal. Estimation of the effect of the acute phase response on indicators of micronutrient status in Indonesian infants. Journal of Nutrition 2002;132(10):3061-6.
185. Wirth JP, Laillou A, Rohner F, Northrop-Clewes CA, Macdonald B, Moench-Pfanner R. Lessons learned from national food fortification projects: Experiences from Morocco, Uzbekistan and Vietnam. Food and Nutrition Bulletin 2012;33(4 Suppl):S281-92.
186. Zimmermann MB, Molinari L, Staubli-Asobayire F, Hess SY, Chaouki N, Adou P, et al. Serum transferrin receptor and zinc protoporphyrin as indicators of iron status in African children. American Journal of Clinical Nutrition 2005;81(3):615-23.
187. Zimmermann MB, Hurrell RF. Nutritional iron deficiency. Lancet 2007;370(9586):511-20.