-
2
-
-
79952257801
-
FurinDB: a database of 20-residue furin cleavage site motifs, substrates and their associated drugs
-
Tian S, Huang Q, Fang Y et al. FurinDB: a database of 20-residue furin cleavage site motifs, substrates and their associated drugs. Int J Mol Sci 2011; 12: 1060–1065.
-
(2011)
Int J Mol Sci
, vol.12
, pp. 1060-1065
-
-
Tian, S.1
Huang, Q.2
Fang, Y.3
-
3
-
-
0014200189
-
Insulin biosynthesis: evidence for a precursor
-
Steiner DF, Cunningham D, Spigelman L et al. Insulin biosynthesis: evidence for a precursor. Science 1967; 157: 697–700.
-
(1967)
Science
, vol.157
, pp. 697-700
-
-
Steiner, D.F.1
Cunningham, D.2
Spigelman, L.3
-
4
-
-
0022779175
-
Evolutionary conserved close linkage of the c-fes/fps proto-oncogene and genetic sequences encoding a receptor-like protein
-
Roebroek AJ, Schalken JA, Leunissen JA et al. Evolutionary conserved close linkage of the c-fes/fps proto-oncogene and genetic sequences encoding a receptor-like protein. EMBO J 1986; 5: 2197–2202.
-
(1986)
EMBO J
, vol.5
, pp. 2197-2202
-
-
Roebroek, A.J.1
Schalken, J.A.2
Leunissen, J.A.3
-
5
-
-
0025522624
-
Furin is a subtilisin-like proprotein processing enzyme in higher eukaryotes
-
van de Ven WJ, Voorberg J, Fontijn R et al. Furin is a subtilisin-like proprotein processing enzyme in higher eukaryotes. Mol Biol Rep 1990; 14: 265–275.
-
(1990)
Mol Biol Rep
, vol.14
, pp. 265-275
-
-
van de Ven, W.J.1
Voorberg, J.2
Fontijn, R.3
-
6
-
-
84860383419
-
The biology and therapeutic targeting of the proprotein convertases
-
Seidah NG, Prat A. The biology and therapeutic targeting of the proprotein convertases. Nat Rev Drug Discov 2012; 11: 367–383.
-
(2012)
Nat Rev Drug Discov
, vol.11
, pp. 367-383
-
-
Seidah, N.G.1
Prat, A.2
-
7
-
-
0033529545
-
Secreted site-1 protease cleaves peptides corresponding to luminal loop of sterol regulatory element-binding proteins
-
Cheng D, Espenshade PJ, Slaughter CA et al. Secreted site-1 protease cleaves peptides corresponding to luminal loop of sterol regulatory element-binding proteins. J Biol Chem 1999; 274: 22805–22812.
-
(1999)
J Biol Chem
, vol.274
, pp. 22805-22812
-
-
Cheng, D.1
Espenshade, P.J.2
Slaughter, C.A.3
-
8
-
-
34547137377
-
Catalytic activity is not required for secreted PCSK9 to reduce low density lipoprotein receptors in HepG2 cells
-
McNutt MC, Lagace TA, Horton JD. Catalytic activity is not required for secreted PCSK9 to reduce low density lipoprotein receptors in HepG2 cells. J Biol Chem 2007; 282: 20799–20803.
-
(2007)
J Biol Chem
, vol.282
, pp. 20799-20803
-
-
McNutt, M.C.1
Lagace, T.A.2
Horton, J.D.3
-
9
-
-
84920269464
-
Tissue-based map of the human proteome
-
Uhlén M, Fagerberg L, Hallström BM et al. Tissue-based map of the human proteome. Science 2015; 347: 1260419.
-
(2015)
Science
, vol.347
, pp. 1260419
-
-
Uhlén, M.1
Fagerberg, L.2
Hallström, B.M.3
-
10
-
-
0028292383
-
Expression of the dibasic proprotein processing enzyme furin is directed by multiple promoters
-
Ayoubi TA, Creemers JW, Roebroek AJ et al. Expression of the dibasic proprotein processing enzyme furin is directed by multiple promoters. J Biol Chem 1994; 269: 9298–9303.
-
(1994)
J Biol Chem
, vol.269
, pp. 9298-9303
-
-
Ayoubi, T.A.1
Creemers, J.W.2
Roebroek, A.J.3
-
11
-
-
33746600246
-
Proprotein convertase furin is preferentially expressed in T helper 1 cells and regulates interferon γ
-
Pesu M, Muul L, Kanno Y et al. Proprotein convertase furin is preferentially expressed in T helper 1 cells and regulates interferon γ. Blood 2006; 108: 983–985.
-
(2006)
Blood
, vol.108
, pp. 983-985
-
-
Pesu, M.1
Muul, L.2
Kanno, Y.3
-
12
-
-
0030612684
-
TGFβ1 regulates gene expression of its own converting enzyme furin
-
Blanchette F, Day R, Dong W et al. TGFβ1 regulates gene expression of its own converting enzyme furin. J Clin Invest 1997; 99: 1974–1983.
-
(1997)
J Clin Invest
, vol.99
, pp. 1974-1983
-
-
Blanchette, F.1
Day, R.2
Dong, W.3
-
13
-
-
0028362008
-
The convertases furin and PC1 can both cleave the human immunodeficiency virus (HIV)-1 envelope glycoprotein gp160 into gp120 (HIV-1 SU) and gp41 (HIV-I TM)
-
Decroly E, Vandenbranden M, Ruysschaert JM et al. The convertases furin and PC1 can both cleave the human immunodeficiency virus (HIV)-1 envelope glycoprotein gp160 into gp120 (HIV-1 SU) and gp41 (HIV-I TM). J Biol Chem 1994; 269: 12240–12247.
-
(1994)
J Biol Chem
, vol.269
, pp. 12240-12247
-
-
Decroly, E.1
Vandenbranden, M.2
Ruysschaert, J.M.3
-
14
-
-
84885766791
-
Processing of human toll-like receptor 7 by furin-like proprotein convertases is required for its accumulation and activity in endosomes
-
Hipp MM, Shepherd D, Gileadi U et al. Processing of human toll-like receptor 7 by furin-like proprotein convertases is required for its accumulation and activity in endosomes. Immunity 2013; 39: 711–721.
-
(2013)
Immunity
, vol.39
, pp. 711-721
-
-
Hipp, M.M.1
Shepherd, D.2
Gileadi, U.3
-
15
-
-
0027421103
-
Intramolecular chaperones and protein folding
-
Shinde U, Inouye M. Intramolecular chaperones and protein folding. Trends Biochem Sci 1993; 18: 442–446.
-
(1993)
Trends Biochem Sci
, vol.18
, pp. 442-446
-
-
Shinde, U.1
Inouye, M.2
-
16
-
-
0031001304
-
Activation of the furin endoprotease is a multiple-step process: requirements for acidification and internal propeptide cleavage
-
Anderson ED, VanSlyke JK, Thulin CD et al. Activation of the furin endoprotease is a multiple-step process: requirements for acidification and internal propeptide cleavage. EMBO J 1997; 16: 1508–1518.
-
(1997)
EMBO J
, vol.16
, pp. 1508-1518
-
-
Anderson, E.D.1
VanSlyke, J.K.2
Thulin, C.D.3
-
17
-
-
0036791359
-
Furin at the cutting edge: from protein traffic to embryogenesis and disease
-
Thomas G. Furin at the cutting edge: from protein traffic to embryogenesis and disease. Nat Rev Mol Cell Biol 2002; 3: 753–766.
-
(2002)
Nat Rev Mol Cell Biol
, vol.3
, pp. 753-766
-
-
Thomas, G.1
-
18
-
-
0028107656
-
Intracellular trafficking and activation of the furin proprotein convertase: localization to the TGN and recycling from the cell surface
-
Molloy SS, Thomas L, VanSlyke JK et al. Intracellular trafficking and activation of the furin proprotein convertase: localization to the TGN and recycling from the cell surface. EMBO J 1994; 13: 18–33.
-
(1994)
EMBO J
, vol.13
, pp. 18-33
-
-
Molloy, S.S.1
Thomas, L.2
VanSlyke, J.K.3
-
19
-
-
0028605962
-
Maturation of the trans-Golgi network protease furin: compartmentalization of propeptide removal, substrate cleavage, and COOH-terminal truncation
-
Vey M, Schäfer W, Berghöfer S et al. Maturation of the trans-Golgi network protease furin: compartmentalization of propeptide removal, substrate cleavage, and COOH-terminal truncation. J Cell Biol 1994; 127: 1829–1842.
-
(1994)
J Cell Biol
, vol.127
, pp. 1829-1842
-
-
Vey, M.1
Schäfer, W.2
Berghöfer, S.3
-
20
-
-
0035868365
-
“Shed” furin: mapping of the cleavage determinants and identification of its C-terminus
-
Plaimauer B, Mohr G, Wernhart W et al. “Shed” furin: mapping of the cleavage determinants and identification of its C-terminus. Biochem J 2001; 354: 689–695.
-
(2001)
Biochem J
, vol.354
, pp. 689-695
-
-
Plaimauer, B.1
Mohr, G.2
Wernhart, W.3
-
21
-
-
77649161633
-
A 20 Residues motif delineates the furin cleavage site and its physical properties may influence viral fusion
-
Tian S. A 20 Residues motif delineates the furin cleavage site and its physical properties may influence viral fusion. Biochem Insights 2009; 2: BCI.S2049.
-
(2009)
Biochem Insights
, vol.2
, pp. BCI.S2049
-
-
Tian, S.1
-
22
-
-
27644578453
-
Proprotein convertases [corrected] are responsible for proteolysis and inactivation of endothelial lipase
-
Jin W, Fuki IV, Seidah NG et al. Proprotein convertases [corrected] are responsible for proteolysis and inactivation of endothelial lipase. J Biol Chem 2005; 280: 36551–36559.
-
(2005)
J Biol Chem
, vol.280
, pp. 36551-36559
-
-
Jin, W.1
Fuki, I.V.2
Seidah, N.G.3
-
23
-
-
79953022875
-
In vivo evidence that furin from hepatocytes inactivates PCSK9
-
Essalmani R, Susan-Resiga D, Chamberland A et al. In vivo evidence that furin from hepatocytes inactivates PCSK9. J Biol Chem 2011; 286: 4257–4263.
-
(2011)
J Biol Chem
, vol.286
, pp. 4257-4263
-
-
Essalmani, R.1
Susan-Resiga, D.2
Chamberland, A.3
-
24
-
-
0032443652
-
Failure of ventral closure and axial rotation in embryos lacking the proprotein convertase Furin
-
Roebroek AJ, Umans L, Pauli IG et al. Failure of ventral closure and axial rotation in embryos lacking the proprotein convertase Furin. Development 1998; 125: 4863–4876.
-
(1998)
Development
, vol.125
, pp. 4863-4876
-
-
Roebroek, A.J.1
Umans, L.2
Pauli, I.G.3
-
25
-
-
84866280245
-
Loss of endothelial furin leads to cardiac malformation and early postnatal death
-
Kim W, Essalmani R, Szumska D et al. Loss of endothelial furin leads to cardiac malformation and early postnatal death. Mol Cell Biol 2012; 32: 3382–3391.
-
(2012)
Mol Cell Biol
, vol.32
, pp. 3382-3391
-
-
Kim, W.1
Essalmani, R.2
Szumska, D.3
-
26
-
-
0035912849
-
Mutations within a furin consensus sequence block proteolytic release of ectodysplasin-A and cause X-linked hypohidrotic ectodermal dysplasia
-
Chen Y, Molloy SS, Thomas L et al. Mutations within a furin consensus sequence block proteolytic release of ectodysplasin-A and cause X-linked hypohidrotic ectodermal dysplasia. Proc Natl Acad Sci USA 2001; 98: 7218–7223.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 7218-7223
-
-
Chen, Y.1
Molloy, S.S.2
Thomas, L.3
-
27
-
-
0025292828
-
Haemophilia B: database of point mutations and short additions and deletions
-
Giannelli F, Green PM, High KA et al. Haemophilia B: database of point mutations and short additions and deletions. Nucleic Acids Res 1990; 18: 4053–4059.
-
(1990)
Nucleic Acids Res
, vol.18
, pp. 4053-4059
-
-
Giannelli, F.1
Green, P.M.2
High, K.A.3
-
28
-
-
27644521904
-
Proprotein convertases: “master switches” in the regulation of tumor growth and progression
-
Bassi DE, Fu J, Lopez de Cicco R et al. Proprotein convertases: “master switches” in the regulation of tumor growth and progression. Mol Carcinog 2005; 44: 151–161.
-
(2005)
Mol Carcinog
, vol.44
, pp. 151-161
-
-
Bassi, D.E.1
Fu, J.2
Lopez de Cicco, R.3
-
29
-
-
85020131888
-
Proprotein convertase inhibition: paralyzing the cell's master switches
-
Klein-Szanto AJ, Bassi DE. Proprotein convertase inhibition: paralyzing the cell's master switches. Biochem Pharmacol 2017; 140: 8–15.
-
(2017)
Biochem Pharmacol
, vol.140
, pp. 8-15
-
-
Klein-Szanto, A.J.1
Bassi, D.E.2
-
30
-
-
85020943811
-
The proprotein convertase furin in tumour progression: the PC furin in tumour progression
-
Jaaks P, Bernasconi M. The proprotein convertase furin in tumour progression: the PC furin in tumour progression. Int J Cancer 2017; 141: 654–663.
-
(2017)
Int J Cancer
, vol.141
, pp. 654-663
-
-
Jaaks, P.1
Bernasconi, M.2
-
31
-
-
14844299760
-
Hypoxia-enhanced expression of the proprotein convertase furin is mediated by hypoxia-inducible factor-1: impact on the bioactivation of proproteins
-
McMahon S, Grondin F, McDonald PP et al. Hypoxia-enhanced expression of the proprotein convertase furin is mediated by hypoxia-inducible factor-1: impact on the bioactivation of proproteins. J Biol Chem 2005; 280: 6561–6569.
-
(2005)
J Biol Chem
, vol.280
, pp. 6561-6569
-
-
McMahon, S.1
Grondin, F.2
McDonald, P.P.3
-
32
-
-
82155192278
-
Hypoxia enhances cancer cell invasion through relocalization of the proprotein convertase furin from the trans-Golgi network to the cell surface
-
Arsenault D, Lucien F, Dubois CM. Hypoxia enhances cancer cell invasion through relocalization of the proprotein convertase furin from the trans-Golgi network to the cell surface. J Cell Physiol 2012; 227: 789–800.
-
(2012)
J Cell Physiol
, vol.227
, pp. 789-800
-
-
Arsenault, D.1
Lucien, F.2
Dubois, C.M.3
-
33
-
-
0036796781
-
Get a ligand, get a life: integrins, signaling and cell survival
-
Stupack DG, Cheresh DA. Get a ligand, get a life: integrins, signaling and cell survival. J Cell Sci 2002; 115: 3729–3738.
-
(2002)
J Cell Sci
, vol.115
, pp. 3729-3738
-
-
Stupack, D.G.1
Cheresh, D.A.2
-
34
-
-
85048476255
-
TGF-β in T cell biology: implications for cancer immunotherapy
-
Dahmani A, Delisle J-S. TGF-β in T cell biology: implications for cancer immunotherapy. Cancers 2018; 10: 194.
-
(2018)
Cancers
, vol.10
, pp. 194
-
-
Dahmani, A.1
Delisle, J.-S.2
-
35
-
-
51649112340
-
T cell-expressed proprotein convertase furin is essential for maintenance of peripheral tolerance
-
Pesu M, Watford WT, Wei L et al. T cell-expressed proprotein convertase furin is essential for maintenance of peripheral tolerance. Nature 2008; 455: 246–250.
-
(2008)
Nature
, vol.455
, pp. 246-250
-
-
Pesu, M.1
Watford, W.T.2
Wei, L.3
-
36
-
-
78650827011
-
Development and characterisation of an assay for furin activity
-
Bourne GL, Grainger DJ. Development and characterisation of an assay for furin activity. J Immunol Methods 2011; 364: 101–108.
-
(2011)
J Immunol Methods
, vol.364
, pp. 101-108
-
-
Bourne, G.L.1
Grainger, D.J.2
-
37
-
-
85039860563
-
The dark side of IFN-γ: its role in promoting cancer immunoevasion
-
Mojic M, Takeda K, Hayakawa Y. The dark side of IFN-γ: its role in promoting cancer immunoevasion. Int J Mol Sci 2017; 19: 89.
-
(2017)
Int J Mol Sci
, vol.19
, pp. 89
-
-
Mojic, M.1
Takeda, K.2
Hayakawa, Y.3
-
38
-
-
84991781106
-
Radiotherapy-associated furin expression and tumor invasiveness in recurrent laryngeal cancer
-
Lee M, Ryu CH, Chang HW et al. Radiotherapy-associated furin expression and tumor invasiveness in recurrent laryngeal cancer. Anticancer Res 2016; 36: 5117–5125.
-
(2016)
Anticancer Res
, vol.36
, pp. 5117-5125
-
-
Lee, M.1
Ryu, C.H.2
Chang, H.W.3
-
39
-
-
0028089159
-
Proteolytic activation of bacterial toxins: role of bacterial and host cell proteases
-
Gordon VM, Leppla SH. Proteolytic activation of bacterial toxins: role of bacterial and host cell proteases. Infect Immun 1994; 62: 333–340.
-
(1994)
Infect Immun
, vol.62
, pp. 333-340
-
-
Gordon, V.M.1
Leppla, S.H.2
-
40
-
-
0027495717
-
Evidence for involvement of furin in cleavage and activation of diphtheria toxin
-
Tsuneoka M, Nakayama K, Hatsuzawa K et al. Evidence for involvement of furin in cleavage and activation of diphtheria toxin. J Biol Chem 1993; 268: 26461–26465.
-
(1993)
J Biol Chem
, vol.268
, pp. 26461-26465
-
-
Tsuneoka, M.1
Nakayama, K.2
Hatsuzawa, K.3
-
41
-
-
0026455183
-
Cell-mediated cleavage of Pseudomonas exotoxin between Arg279 and Gly280 generates the enzymatically active fragment which translocates to the cytosol
-
Ogata M, Fryling CM, Pastan I et al. Cell-mediated cleavage of Pseudomonas exotoxin between Arg279 and Gly280 generates the enzymatically active fragment which translocates to the cytosol. J Biol Chem 1992; 267: 25396–25401.
-
(1992)
J Biol Chem
, vol.267
, pp. 25396-25401
-
-
Ogata, M.1
Fryling, C.M.2
Pastan, I.3
-
42
-
-
0014202360
-
Effect of diphtheria toxin on protein synthesis: inactivation of one of the transfer factors
-
Collier RJ. Effect of diphtheria toxin on protein synthesis: inactivation of one of the transfer factors. J Mol Biol 1967; 25: 83–98.
-
(1967)
J Mol Biol
, vol.25
, pp. 83-98
-
-
Collier, R.J.1
-
43
-
-
0025203984
-
Cellular processing of the interleukin-2 fusion toxin DAB486-IL-2 and efficient delivery of diphtheria fragment A to the cytosol of target cells requires Arg194
-
Williams DP, Wen Z, Watson RS et al. Cellular processing of the interleukin-2 fusion toxin DAB486-IL-2 and efficient delivery of diphtheria fragment A to the cytosol of target cells requires Arg194. J Biol Chem 1990; 265: 20673–20677.
-
(1990)
J Biol Chem
, vol.265
, pp. 20673-20677
-
-
Williams, D.P.1
Wen, Z.2
Watson, R.S.3
-
44
-
-
0026775916
-
Human furin is a calcium-dependent serine endoprotease that recognizes the sequence Arg-X-X-Arg and efficiently cleaves anthrax toxin protective antigen
-
Molloy SS, Bresnahan PA, Leppla SH et al. Human furin is a calcium-dependent serine endoprotease that recognizes the sequence Arg-X-X-Arg and efficiently cleaves anthrax toxin protective antigen. J Biol Chem 1992; 267: 16396–16402.
-
(1992)
J Biol Chem
, vol.267
, pp. 16396-16402
-
-
Molloy, S.S.1
Bresnahan, P.A.2
Leppla, S.H.3
-
45
-
-
0036070576
-
Bacteriophage control of bacterial virulence
-
Wagner PL, Waldor MK. Bacteriophage control of bacterial virulence. Infect Immun 2002; 70: 3985–3993.
-
(2002)
Infect Immun
, vol.70
, pp. 3985-3993
-
-
Wagner, P.L.1
Waldor, M.K.2
-
46
-
-
0028123337
-
Host cell proteases controlling virus pathogenicity
-
Klenk HD, Garten W. Host cell proteases controlling virus pathogenicity. Trends Microbiol 1994; 2: 39–43.
-
(1994)
Trends Microbiol
, vol.2
, pp. 39-43
-
-
Klenk, H.D.1
Garten, W.2
-
48
-
-
0023803844
-
The molecular biology of influenza virus pathogenicity
-
Klenk HD, Rott R. The molecular biology of influenza virus pathogenicity. Adv Virus Res 1988; 34: 247–281.
-
(1988)
Adv Virus Res
, vol.34
, pp. 247-281
-
-
Klenk, H.D.1
Rott, R.2
-
49
-
-
0034634728
-
Maturation of HIV envelope glycoprotein precursors by cellular endoproteases
-
Moulard M, Decroly E. Maturation of HIV envelope glycoprotein precursors by cellular endoproteases. Biochim Biophys Acta 2000; 1469: 121–132.
-
(2000)
Biochim Biophys Acta
, vol.1469
, pp. 121-132
-
-
Moulard, M.1
Decroly, E.2
-
50
-
-
0026577244
-
Immunological analysis of human immunodeficiency virus type 1 envelope glycoprotein proteolytic cleavage
-
Fenouillet E, Gluckman JC. Immunological analysis of human immunodeficiency virus type 1 envelope glycoprotein proteolytic cleavage. Virology 1992; 187: 825–828.
-
(1992)
Virology
, vol.187
, pp. 825-828
-
-
Fenouillet, E.1
Gluckman, J.C.2
-
51
-
-
0023678264
-
Improved antigenicity of the HIV env protein by cleavage site removal
-
Kieny MP, Lathe R, Rivière Y et al. Improved antigenicity of the HIV env protein by cleavage site removal. Protein Eng 1988; 2: 219–225.
-
(1988)
Protein Eng
, vol.2
, pp. 219-225
-
-
Kieny, M.P.1
Lathe, R.2
Rivière, Y.3
-
52
-
-
0032924008
-
The extracellular processing of HIV-1 envelope glycoprotein gp160 by human plasmin
-
Okumura Y, Yano M, Murakami M et al. The extracellular processing of HIV-1 envelope glycoprotein gp160 by human plasmin. FEBS Lett 1999; 442: 39–42.
-
(1999)
FEBS Lett
, vol.442
, pp. 39-42
-
-
Okumura, Y.1
Yano, M.2
Murakami, M.3
-
53
-
-
0023136546
-
Role of Staphylococcus protease in the development of influenza pneumonia
-
Tashiro M, Ciborowski P, Klenk H-D et al. Role of Staphylococcus protease in the development of influenza pneumonia. Nature 1987; 325: 536.
-
(1987)
Nature
, vol.325
, pp. 536
-
-
Tashiro, M.1
Ciborowski, P.2
Klenk, H.-D.3
-
54
-
-
84939654675
-
Influenza virus activating host proteases: identification, localization and inhibitors as potential therapeutics
-
Garten W, Braden C, Arendt A et al. Influenza virus activating host proteases: identification, localization and inhibitors as potential therapeutics. Eur J Cell Biol 2015; 94: 375–383.
-
(2015)
Eur J Cell Biol
, vol.94
, pp. 375-383
-
-
Garten, W.1
Braden, C.2
Arendt, A.3
-
55
-
-
33748950305
-
Proteolytic activation of influenza viruses by serine proteases TMPRSS2 and HAT from human airway epithelium
-
Böttcher E, Matrosovich T, Beyerle M et al. Proteolytic activation of influenza viruses by serine proteases TMPRSS2 and HAT from human airway epithelium. J Virol 2006; 80: 9896–9898.
-
(2006)
J Virol
, vol.80
, pp. 9896-9898
-
-
Böttcher, E.1
Matrosovich, T.2
Beyerle, M.3
-
56
-
-
0026643396
-
Influenza virus hemagglutinin with multibasic cleavage site is activated by furin, a subtilisin-like endoprotease
-
Stieneke-Gröber A, Vey M, Angliker H et al. Influenza virus hemagglutinin with multibasic cleavage site is activated by furin, a subtilisin-like endoprotease. EMBO J 1992; 11: 2407–2414.
-
(1992)
EMBO J
, vol.11
, pp. 2407-2414
-
-
Stieneke-Gröber, A.1
Vey, M.2
Angliker, H.3
-
57
-
-
0028095251
-
Proprotein-processing endoproteases PC6 and furin both activate hemagglutinin of virulent avian influenza viruses
-
Horimoto T, Nakayama K, Smeekens SP et al. Proprotein-processing endoproteases PC6 and furin both activate hemagglutinin of virulent avian influenza viruses. J Virol 1994; 68: 6074–6078.
-
(1994)
J Virol
, vol.68
, pp. 6074-6078
-
-
Horimoto, T.1
Nakayama, K.2
Smeekens, S.P.3
-
58
-
-
0030905724
-
Virulence-associated sequence duplication at the hemagglutinin cleavage site of avian influenza viruses
-
Perdue ML, García M, Senne D et al. Virulence-associated sequence duplication at the hemagglutinin cleavage site of avian influenza viruses. Virus Res 1997; 49: 173–186.
-
(1997)
Virus Res
, vol.49
, pp. 173-186
-
-
Perdue, M.L.1
García, M.2
Senne, D.3
-
59
-
-
0343337638
-
Different hemagglutinin cleavage site variants of H7N7 in an influenza outbreak in chickens in Leipzig, Germany
-
Röhm C, Süss J, Pohle V et al. Different hemagglutinin cleavage site variants of H7N7 in an influenza outbreak in chickens in Leipzig, Germany. Virology 1996; 218: 253–257.
-
(1996)
Virology
, vol.218
, pp. 253-257
-
-
Röhm, C.1
Süss, J.2
Pohle, V.3
-
60
-
-
0024521692
-
Mutations at the cleavage site of the hemagglutinin alter the pathogenicity of influenza virus a/chick/penn/83 (H5N2)
-
Ohuchi M, Orlich M, Ohuchi R et al. Mutations at the cleavage site of the hemagglutinin alter the pathogenicity of influenza virus a/chick/penn/83 (H5N2). Virology 1989; 168: 274–280.
-
(1989)
Virology
, vol.168
, pp. 274-280
-
-
Ohuchi, M.1
Orlich, M.2
Ohuchi, R.3
-
61
-
-
84873046900
-
Matriptase, HAT, and TMPRSS2 activate the hemagglutinin of H9N2 influenza A viruses
-
Baron J, Tarnow C, Mayoli-Nüssle D et al. Matriptase, HAT, and TMPRSS2 activate the hemagglutinin of H9N2 influenza A viruses. J Virol 2013; 87: 1811–1820.
-
(2013)
J Virol
, vol.87
, pp. 1811-1820
-
-
Baron, J.1
Tarnow, C.2
Mayoli-Nüssle, D.3
-
62
-
-
84892475040
-
A novel activation mechanism of avian influenza virus H9N2 by furin
-
Tse LV, Hamilton AM, Friling T et al. A novel activation mechanism of avian influenza virus H9N2 by furin. J Virol 2014; 88: 1673–1683.
-
(2014)
J Virol
, vol.88
, pp. 1673-1683
-
-
Tse, L.V.1
Hamilton, A.M.2
Friling, T.3
-
63
-
-
0032510732
-
Processing of the Ebola virus glycoprotein by the proprotein convertase furin
-
Volchkov VE, Feldmann H, Volchkova VA et al. Processing of the Ebola virus glycoprotein by the proprotein convertase furin. Proc Natl Acad Sci USA 1998; 95: 5762–5767.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 5762-5767
-
-
Volchkov, V.E.1
Feldmann, H.2
Volchkova, V.A.3
-
64
-
-
0034101994
-
Proteolytic processing of Marburg virus glycoprotein
-
Volchkov VE, Volchkova VA, Ströher U et al. Proteolytic processing of Marburg virus glycoprotein. Virology 2000; 268: 1–6.
-
(2000)
Virology
, vol.268
, pp. 1-6
-
-
Volchkov, V.E.1
Volchkova, V.A.2
Ströher, U.3
-
65
-
-
0032949982
-
Endoproteolytic processing of the Ebola virus envelope glycoprotein: cleavage is not required for function
-
Wool-Lewis RJ, Bates P. Endoproteolytic processing of the Ebola virus envelope glycoprotein: cleavage is not required for function. J Virol 1999; 73: 1419–1426.
-
(1999)
J Virol
, vol.73
, pp. 1419-1426
-
-
Wool-Lewis, R.J.1
Bates, P.2
-
66
-
-
33947431606
-
Proteolytic processing of the Ebola virus glycoprotein is not critical for Ebola virus replication in nonhuman primates
-
Neumann G, Geisbert TW, Ebihara H et al. Proteolytic processing of the Ebola virus glycoprotein is not critical for Ebola virus replication in nonhuman primates. J Virol 2007; 81: 2995–2998.
-
(2007)
J Virol
, vol.81
, pp. 2995-2998
-
-
Neumann, G.1
Geisbert, T.W.2
Ebihara, H.3
-
67
-
-
0029589329
-
GP mRNA of Ebola virus is edited by the Ebola virus polymerase and by T7 and vaccinia virus polymerases
-
Volchkov VE, Becker S, Volchkova VA et al. GP mRNA of Ebola virus is edited by the Ebola virus polymerase and by T7 and vaccinia virus polymerases. Virology 1995; 214: 421–430.
-
(1995)
Virology
, vol.214
, pp. 421-430
-
-
Volchkov, V.E.1
Becker, S.2
Volchkova, V.A.3
-
68
-
-
0033527892
-
∆-peptide is the carboxy-terminal cleavage fragment of the nonstructural small glycoprotein sGP of Ebola virus
-
Volchkova VA, Klenk HD, Volchkov VE. ∆-peptide is the carboxy-terminal cleavage fragment of the nonstructural small glycoprotein sGP of Ebola virus. Virology 1999; 265: 164–171.
-
(1999)
Virology
, vol.265
, pp. 164-171
-
-
Volchkova, V.A.1
Klenk, H.D.2
Volchkov, V.E.3
-
70
-
-
84859500348
-
Degrees of maturity: the complex structure and biology of flaviviruses
-
Pierson TC, Diamond MS. Degrees of maturity: the complex structure and biology of flaviviruses. Curr Opin Virol 2012; 2: 168–175.
-
(2012)
Curr Opin Virol
, vol.2
, pp. 168-175
-
-
Pierson, T.C.1
Diamond, M.S.2
-
71
-
-
0025855266
-
Fusion activity of flaviviruses: comparison of mature and immature (prM-containing) tick-borne encephalitis virions
-
Guirakhoo F, Heinz FX, Mandl CW et al. Fusion activity of flaviviruses: comparison of mature and immature (prM-containing) tick-borne encephalitis virions. J Gen Virol 1991; 72: 1323–1329.
-
(1991)
J Gen Virol
, vol.72
, pp. 1323-1329
-
-
Guirakhoo, F.1
Heinz, F.X.2
Mandl, C.W.3
-
72
-
-
41349112304
-
Structure of the immature dengue virus at low pH primes proteolytic maturation
-
Yu I-M, Zhang W, Holdaway HA et al. Structure of the immature dengue virus at low pH primes proteolytic maturation. Science 2008; 319: 1834–1837.
-
(2008)
Science
, vol.319
, pp. 1834-1837
-
-
Yu, I.-M.1
Zhang, W.2
Holdaway, H.A.3
-
73
-
-
70450208515
-
Association of the pr peptides with dengue virus at acidic pH blocks membrane fusion
-
Yu I-M, Holdaway HA, Chipman PR et al. Association of the pr peptides with dengue virus at acidic pH blocks membrane fusion. J Virol 2009; 83: 12101–12107.
-
(2009)
J Virol
, vol.83
, pp. 12101-12107
-
-
Yu, I.-M.1
Holdaway, H.A.2
Chipman, P.R.3
-
74
-
-
0037236396
-
Cleavage of protein prM is necessary for infection of BHK-21 cells by tick-borne encephalitis virus
-
Elshuber S, Allison SL, Heinz FX et al. Cleavage of protein prM is necessary for infection of BHK-21 cells by tick-borne encephalitis virus. J Gen Virol 2003; 84: 183–191.
-
(2003)
J Gen Virol
, vol.84
, pp. 183-191
-
-
Elshuber, S.1
Allison, S.L.2
Heinz, F.X.3
-
75
-
-
58149388463
-
Functional importance of dengue virus maturation: infectious properties of immature virions
-
Zybert IA, van der Ende-Metselaar H, Wilschut J et al. Functional importance of dengue virus maturation: infectious properties of immature virions. J Gen Virol 2008; 89: 3047–3051.
-
(2008)
J Gen Virol
, vol.89
, pp. 3047-3051
-
-
Zybert, I.A.1
van der Ende-Metselaar, H.2
Wilschut, J.3
-
76
-
-
31144445030
-
West Nile virus discriminates between DC-SIGN and DC-SIGNR for cellular attachment and infection
-
Davis CW, Nguyen H-Y, Hanna SL et al. West Nile virus discriminates between DC-SIGN and DC-SIGNR for cellular attachment and infection. J Virol 2006; 80: 1290–1301.
-
(2006)
J Virol
, vol.80
, pp. 1290-1301
-
-
Davis, C.W.1
Nguyen, H.-Y.2
Hanna, S.L.3
-
78
-
-
55249088356
-
Differential modulation of prM cleavage, extracellular particle distribution, and virus infectivity by conserved residues at nonfurin consensus positions of the dengue virus pr-M junction
-
Junjhon J, Lausumpao M, Supasa S et al. Differential modulation of prM cleavage, extracellular particle distribution, and virus infectivity by conserved residues at nonfurin consensus positions of the dengue virus pr-M junction. J Virol 2008; 82: 10776–10791.
-
(2008)
J Virol
, vol.82
, pp. 10776-10791
-
-
Junjhon, J.1
Lausumpao, M.2
Supasa, S.3
-
79
-
-
31944439998
-
Cleavage of the papillomavirus minor capsid protein, L2, at a furin consensus site is necessary for infection
-
Richards RM, Lowy DR, Schiller JT et al. Cleavage of the papillomavirus minor capsid protein, L2, at a furin consensus site is necessary for infection. Proc Natl Acad Sci USA 2006; 103: 1522–1527.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 1522-1527
-
-
Richards, R.M.1
Lowy, D.R.2
Schiller, J.T.3
-
80
-
-
74749099125
-
The role of furin in papillomavirus infection
-
Day PM, Schiller JT. The role of furin in papillomavirus infection. Future Microbiol 2009; 4: 1255–1262.
-
(2009)
Future Microbiol
, vol.4
, pp. 1255-1262
-
-
Day, P.M.1
Schiller, J.T.2
-
81
-
-
42449153250
-
Mechanisms of human papillomavirus type 16 neutralization by l2 cross-neutralizing and l1 type-specific antibodies
-
Day PM, Gambhira R, Roden RBS et al. Mechanisms of human papillomavirus type 16 neutralization by l2 cross-neutralizing and l1 type-specific antibodies. J Virol 2008; 82: 4638–4646.
-
(2008)
J Virol
, vol.82
, pp. 4638-4646
-
-
Day, P.M.1
Gambhira, R.2
Roden, R.B.S.3
-
82
-
-
64049108517
-
Characterization of genotype-specific carboxyl-terminal cleavage sites of hepatitis B virus e antigen precursor and identification of furin as the candidate enzyme
-
Ito K, Kim K-H, Lok AS-F et al. Characterization of genotype-specific carboxyl-terminal cleavage sites of hepatitis B virus e antigen precursor and identification of furin as the candidate enzyme. J Virol 2009; 83: 3507–3517.
-
(2009)
J Virol
, vol.83
, pp. 3507-3517
-
-
Ito, K.1
Kim, K.-H.2
Lok, A.S.-F.3
-
83
-
-
0037428471
-
Proteolytic processing of the hepatitis B virus e antigen precursor. Cleavage at two furin consensus sequences
-
Messageot F, Salhi S, Eon P et al. Proteolytic processing of the hepatitis B virus e antigen precursor. Cleavage at two furin consensus sequences. J Biol Chem 2003; 278: 891–895.
-
(2003)
J Biol Chem
, vol.278
, pp. 891-895
-
-
Messageot, F.1
Salhi, S.2
Eon, P.3
-
84
-
-
0032519919
-
The secreted hepatitis B precore antigen can modulate the immune response to the nucleocapsid: a mechanism for persistence
-
Milich DR, Chen MK, Hughes JL et al. The secreted hepatitis B precore antigen can modulate the immune response to the nucleocapsid: a mechanism for persistence. J Immunol 1998; 160: 2013–2021.
-
(1998)
J Immunol
, vol.160
, pp. 2013-2021
-
-
Milich, D.R.1
Chen, M.K.2
Hughes, J.L.3
-
85
-
-
6944244922
-
A function of the hepatitis B virus precore protein is to regulate the immune response to the core antigen
-
Chen MT, Billaud J-N, Sällberg M et al. A function of the hepatitis B virus precore protein is to regulate the immune response to the core antigen. Proc Natl Acad Sci USA 2004; 101: 14913–14918.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 14913-14918
-
-
Chen, M.T.1
Billaud, J.-N.2
Sällberg, M.3
-
86
-
-
0024469591
-
The secretory core protein of human hepatitis B virus is expressed on the cell surface
-
Schlicht HJ, Schaller H. The secretory core protein of human hepatitis B virus is expressed on the cell surface. J Virol 1989; 63: 5399–5404.
-
(1989)
J Virol
, vol.63
, pp. 5399-5404
-
-
Schlicht, H.J.1
Schaller, H.2
-
87
-
-
70349229382
-
Influence of a single nucleotide polymorphism in the P1 promoter of the furin gene on transcription activity and hepatitis B virus infection
-
Lei RX, Shi H, Peng XM et al. Influence of a single nucleotide polymorphism in the P1 promoter of the furin gene on transcription activity and hepatitis B virus infection. Hepatology 2009; 50: 763–771.
-
(2009)
Hepatology
, vol.50
, pp. 763-771
-
-
Lei, R.X.1
Shi, H.2
Peng, X.M.3
-
88
-
-
84867647908
-
Rules of engagement: molecular insights from host-virus arms races
-
Daugherty MD, Malik HS. Rules of engagement: molecular insights from host-virus arms races. Annu Rev Genet 2012; 46: 677–700.
-
(2012)
Annu Rev Genet
, vol.46
, pp. 677-700
-
-
Daugherty, M.D.1
Malik, H.S.2
-
89
-
-
84862777555
-
SAMHD1 restricts HIV-1 by reducing the intracellular pool of deoxynucleotide triphosphates
-
Lahouassa H, Daddacha W, Hofmann H et al. SAMHD1 restricts HIV-1 by reducing the intracellular pool of deoxynucleotide triphosphates. Nat Immunol 2012; 13: 223–228.
-
(2012)
Nat Immunol
, vol.13
, pp. 223-228
-
-
Lahouassa, H.1
Daddacha, W.2
Hofmann, H.3
-
90
-
-
84857477766
-
The intracellular DNA sensor IFI16 gene acts as restriction factor for human cytomegalovirus replication
-
Gariano GR, Dell'Oste V, Bronzini M et al. The intracellular DNA sensor IFI16 gene acts as restriction factor for human cytomegalovirus replication. PLoS Pathog 2012; 8: e1002498.
-
(2012)
PLoS Pathog
, vol.8
-
-
Gariano, G.R.1
Dell'Oste, V.2
Bronzini, M.3
-
91
-
-
84883162740
-
Modulation of protease activated receptor 1 influences human metapneumovirus disease severity in a mouse model
-
Aerts L, Hamelin M-È, Rhéaume C et al. Modulation of protease activated receptor 1 influences human metapneumovirus disease severity in a mouse model. PLoS ONE 2013; 8: e72529.
-
(2013)
PLoS ONE
, vol.8
-
-
Aerts, L.1
Hamelin, M.-È.2
Rhéaume, C.3
-
92
-
-
84944629624
-
Neuroinflammation-induced interactions between protease-activated receptor 1 and proprotein convertases in HIV-associated neurocognitive disorder
-
Kim W, Zekas E, Lodge R et al. Neuroinflammation-induced interactions between protease-activated receptor 1 and proprotein convertases in HIV-associated neurocognitive disorder. Mol Cell Biol 2015; 35: 3684–3700.
-
(2015)
Mol Cell Biol
, vol.35
, pp. 3684-3700
-
-
Kim, W.1
Zekas, E.2
Lodge, R.3
-
93
-
-
85060640957
-
HIV-induced neuroinflammation: impact of PAR1 and PAR2 processing by Furin
-
Sachan V, Lodge R, Mihara K et al. HIV-induced neuroinflammation: impact of PAR1 and PAR2 processing by Furin. Cell Death Differ 2019.
-
(2019)
Cell Death Differ
-
-
Sachan, V.1
Lodge, R.2
Mihara, K.3
-
94
-
-
84929324871
-
Identification of potential HIV restriction factors by combining evolutionary genomic signatures with functional analyses
-
McLaren PJ, Gawanbacht A, Pyndiah N et al. Identification of potential HIV restriction factors by combining evolutionary genomic signatures with functional analyses. Retrovirology 2015; 12: 41.
-
(2015)
Retrovirology
, vol.12
, pp. 41
-
-
McLaren, P.J.1
Gawanbacht, A.2
Pyndiah, N.3
-
95
-
-
84961221171
-
Guanylate Binding Protein (GBP) 5 is an interferon-inducible inhibitor of HIV-1 infectivity
-
Krapp C, Hotter D, Gawanbacht A et al. Guanylate Binding Protein (GBP) 5 is an interferon-inducible inhibitor of HIV-1 infectivity. Cell Host Microbe 2016; 19: 504–514.
-
(2016)
Cell Host Microbe
, vol.19
, pp. 504-514
-
-
Krapp, C.1
Hotter, D.2
Gawanbacht, A.3
-
96
-
-
85065235566
-
Guanylate-Binding Proteins 2 and 5 exert broad antiviral activity by inhibiting furin-mediated processing of viral envelope proteins
-
e10
-
Braun E, Hotter D, Koepke L et al. Guanylate-Binding Proteins 2 and 5 exert broad antiviral activity by inhibiting furin-mediated processing of viral envelope proteins. Cell Rep 2019; 27: 2092–2104. e10.
-
(2019)
Cell Rep
, vol.27
, pp. 2092-2104
-
-
Braun, E.1
Hotter, D.2
Koepke, L.3
-
97
-
-
85044653262
-
Distinct prognostic value of mRNA expression of guanylate-binding protein genes in skin cutaneous melanoma
-
Wang Q, Wang X, Liang Q et al. Distinct prognostic value of mRNA expression of guanylate-binding protein genes in skin cutaneous melanoma. Oncol Lett 2018; 15: 7914–7922.
-
(2018)
Oncol Lett
, vol.15
, pp. 7914-7922
-
-
Wang, Q.1
Wang, X.2
Liang, Q.3
-
98
-
-
84904723337
-
Interferon-inducible guanylate binding protein (GBP2) is associated with better prognosis in breast cancer and indicates an efficient T cell response
-
Godoy P, Cadenas C, Hellwig B et al. Interferon-inducible guanylate binding protein (GBP2) is associated with better prognosis in breast cancer and indicates an efficient T cell response. Breast Cancer 2014; 21: 491–499.
-
(2014)
Breast Cancer
, vol.21
, pp. 491-499
-
-
Godoy, P.1
Cadenas, C.2
Hellwig, B.3
-
99
-
-
0027429771
-
Inhibition of HIV-1 gp160-dependent membrane fusion by a furin-directed α 1-antitrypsin variant
-
Anderson ED, Thomas L, Hayflick JS et al. Inhibition of HIV-1 gp160-dependent membrane fusion by a furin-directed α 1-antitrypsin variant. J Biol Chem 1993; 268: 24887–24891.
-
(1993)
J Biol Chem
, vol.268
, pp. 24887-24891
-
-
Anderson, E.D.1
Thomas, L.2
Hayflick, J.S.3
-
100
-
-
0028960688
-
Engineered serine protease inhibitor prevents furin-catalyzed activation of the fusion glycoprotein and production of infectious measles virus
-
Watanabe M, Hirano A, Stenglein S et al. Engineered serine protease inhibitor prevents furin-catalyzed activation of the fusion glycoprotein and production of infectious measles virus. J Virol 1995; 69: 3206–3210.
-
(1995)
J Virol
, vol.69
, pp. 3206-3210
-
-
Watanabe, M.1
Hirano, A.2
Stenglein, S.3
-
102
-
-
0034711298
-
Polyarginines are potent furin inhibitors
-
Cameron A, Appel J, Houghten RA et al. Polyarginines are potent furin inhibitors. J Biol Chem 2000; 275: 36741–36749.
-
(2000)
J Biol Chem
, vol.275
, pp. 36741-36749
-
-
Cameron, A.1
Appel, J.2
Houghten, R.A.3
-
103
-
-
0033607676
-
The prosegments of furin and PC7 as potent inhibitors of proprotein convertases. In vitro and ex vivo assessment of their efficacy and selectivity
-
Zhong M, Munzer JS, Basak A et al. The prosegments of furin and PC7 as potent inhibitors of proprotein convertases. In vitro and ex vivo assessment of their efficacy and selectivity. J Biol Chem 1999; 274: 33913–33920.
-
(1999)
J Biol Chem
, vol.274
, pp. 33913-33920
-
-
Zhong, M.1
Munzer, J.S.2
Basak, A.3
-
104
-
-
35148878210
-
Opposing function of the proprotein convertases furin and PACE4 on breast cancer cells’ malignant phenotypes: role of tissue inhibitors of metalloproteinase-1
-
Lapierre M, Siegfried G, Scamuffa N et al. Opposing function of the proprotein convertases furin and PACE4 on breast cancer cells’ malignant phenotypes: role of tissue inhibitors of metalloproteinase-1. Cancer Res 2007; 67: 9030–9034.
-
(2007)
Cancer Res
, vol.67
, pp. 9030-9034
-
-
Lapierre, M.1
Siegfried, G.2
Scamuffa, N.3
-
105
-
-
0036893450
-
The furin inhibitor hexa-D-arginine blocks the activation of Pseudomonas aeruginosa exotoxin A in vivo
-
Sarac MS, Cameron A, Lindberg I. The furin inhibitor hexa-D-arginine blocks the activation of Pseudomonas aeruginosa exotoxin A in vivo. Infect Immun 2002; 70: 7136–7139.
-
(2002)
Infect Immun
, vol.70
, pp. 7136-7139
-
-
Sarac, M.S.1
Cameron, A.2
Lindberg, I.3
-
106
-
-
58249087702
-
Nona-D-arginine therapy for Pseudomonas aeruginosa keratitis
-
Karicherla P, Hobden JA. Nona-D-arginine therapy for Pseudomonas aeruginosa keratitis. Invest Ophthalmol Vis Sci 2009; 50: 256–262.
-
(2009)
Invest Ophthalmol Vis Sci
, vol.50
, pp. 256-262
-
-
Karicherla, P.1
Hobden, J.A.2
-
107
-
-
77950838153
-
Nona-D-arginine amide for prophylaxis and treatment of experimental Pseudomonas aeruginosa keratitis
-
Karicherla P, Hobden JA. Nona-D-arginine amide for prophylaxis and treatment of experimental Pseudomonas aeruginosa keratitis. Curr Eye Res 2010; 35: 220–224.
-
(2010)
Curr Eye Res
, vol.35
, pp. 220-224
-
-
Karicherla, P.1
Hobden, J.A.2
-
108
-
-
77249117734
-
Potent inhibitors of furin and furin-like proprotein convertases containing decarboxylated P1 arginine mimetics
-
Becker GL, Sielaff F, Than ME et al. Potent inhibitors of furin and furin-like proprotein convertases containing decarboxylated P1 arginine mimetics. J Med Chem 2010; 53: 1067–1075.
-
(2010)
J Med Chem
, vol.53
, pp. 1067-1075
-
-
Becker, G.L.1
Sielaff, F.2
Than, M.E.3
-
109
-
-
0037743535
-
The crystal structure of the proprotein processing proteinase furin explains its stringent specificity
-
Henrich S, Cameron A, Bourenkov GP et al. The crystal structure of the proprotein processing proteinase furin explains its stringent specificity. Nat Struct Biol 2003; 10: 520–526.
-
(2003)
Nat Struct Biol
, vol.10
, pp. 520-526
-
-
Henrich, S.1
Cameron, A.2
Bourenkov, G.P.3
-
110
-
-
84924978499
-
Therapeutic uses of furin and its inhibitors: a patent review
-
Couture F, Kwiatkowska A, Dory YL et al. Therapeutic uses of furin and its inhibitors: a patent review. Expert Opin Ther Pat 2015; 25: 379–396.
-
(2015)
Expert Opin Ther Pat
, vol.25
, pp. 379-396
-
-
Couture, F.1
Kwiatkowska, A.2
Dory, Y.L.3
-
111
-
-
32044433491
-
Guanidinylated 2,5-dideoxystreptamine derivatives as anthrax lethal factor inhibitors
-
Jiao G-S, Cregar L, Goldman ME et al. Guanidinylated 2,5-dideoxystreptamine derivatives as anthrax lethal factor inhibitors. Bioorg Med Chem Lett 2006; 16: 1527–1531.
-
(2006)
Bioorg Med Chem Lett
, vol.16
, pp. 1527-1531
-
-
Jiao, G.-S.1
Cregar, L.2
Goldman, M.E.3
-
112
-
-
85019551170
-
Structural studies revealed active site distortions of human furin by a small molecule inhibitor
-
Dahms SO, Jiao G-S, Than ME. Structural studies revealed active site distortions of human furin by a small molecule inhibitor. ACS Chem Biol 2017; 12: 1211–1216.
-
(2017)
ACS Chem Biol
, vol.12
, pp. 1211-1216
-
-
Dahms, S.O.1
Jiao, G.-S.2
Than, M.E.3
-
113
-
-
0024424169
-
Inhibition of proteolytic activation of influenza virus hemagglutinin by specific peptidyl chloroalkyl ketones
-
Garten W, Stieneke A, Shaw E et al. Inhibition of proteolytic activation of influenza virus hemagglutinin by specific peptidyl chloroalkyl ketones. Virology 1989; 172: 25–31.
-
(1989)
Virology
, vol.172
, pp. 25-31
-
-
Garten, W.1
Stieneke, A.2
Shaw, E.3
-
114
-
-
84867762574
-
Generation and characterization of non-competitive furin-inhibiting nanobodies
-
Zhu J, Declercq J, Roucourt B et al. Generation and characterization of non-competitive furin-inhibiting nanobodies. Biochem J 2012; 448: 73–82.
-
(2012)
Biochem J
, vol.448
, pp. 73-82
-
-
Zhu, J.1
Declercq, J.2
Roucourt, B.3
-
115
-
-
85038587128
-
Regnase-1 and roquin nonredundantly regulate th1 differentiation causing cardiac inflammation and fibrosis
-
Cui X, Mino T, Yoshinaga M et al. Regnase-1 and roquin nonredundantly regulate th1 differentiation causing cardiac inflammation and fibrosis. J Immunol 2017; 199: 4066–4077.
-
(2017)
J Immunol
, vol.199
, pp. 4066-4077
-
-
Cui, X.1
Mino, T.2
Yoshinaga, M.3
-
117
-
-
0026481133
-
Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor
-
Inaba K, Inaba M, Romani N et al. Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor. J Exp Med 1992; 176: 1693–1702.
-
(1992)
J Exp Med
, vol.176
, pp. 1693-1702
-
-
Inaba, K.1
Inaba, M.2
Romani, N.3
-
118
-
-
0028906190
-
Processing of transforming growth factor β 1 precursor by human furin convertase
-
Dubois CM, Laprise MH, Blanchette F et al. Processing of transforming growth factor β 1 precursor by human furin convertase. J Biol Chem 1995; 270: 10618–10624.
-
(1995)
J Biol Chem
, vol.270
, pp. 10618-10624
-
-
Dubois, C.M.1
Laprise, M.H.2
Blanchette, F.3
-
119
-
-
0030893704
-
Contrasting effects of TGF-β1 and TNF-α on the development of dendritic cells from progenitors in mouse bone marrow
-
Yamaguchi Y, Tsumura H, Miwa M et al. Contrasting effects of TGF-β1 and TNF-α on the development of dendritic cells from progenitors in mouse bone marrow. Stem Cells 1997; 15: 144–153.
-
(1997)
Stem Cells
, vol.15
, pp. 144-153
-
-
Yamaguchi, Y.1
Tsumura, H.2
Miwa, M.3
-
120
-
-
84996553234
-
® DNA engineered immunotherapy as maintenance in advanced stage ovarian cancer
-
® DNA engineered immunotherapy as maintenance in advanced stage ovarian cancer. Gynecol Oncol 2016; 143: 504–510.
-
(2016)
Gynecol Oncol
, vol.143
, pp. 504-510
-
-
Oh, J.1
Barve, M.2
Matthews, C.M.3
-
121
-
-
0023811819
-
Human cytomegalovirus strain Towne glycoprotein B is processed by proteolytic cleavage
-
Spaete RR, Thayer RM, Probert WS et al. Human cytomegalovirus strain Towne glycoprotein B is processed by proteolytic cleavage. Virology 1988; 167: 207–225.
-
(1988)
Virology
, vol.167
, pp. 207-225
-
-
Spaete, R.R.1
Thayer, R.M.2
Probert, W.S.3
-
122
-
-
0022481278
-
Identification and structure of the gene encoding gpII, a major glycoprotein of varicella-zoster virus
-
Keller PM, Davison AJ, Lowe RS et al. Identification and structure of the gene encoding gpII, a major glycoprotein of varicella-zoster virus. Virology 1986; 152: 181–191.
-
(1986)
Virology
, vol.152
, pp. 181-191
-
-
Keller, P.M.1
Davison, A.J.2
Lowe, R.S.3
-
123
-
-
0023115697
-
Epstein-Barr virus glycoprotein homologous to herpes simplex virus gB
-
Gong M, Ooka T, Matsuo T et al. Epstein-Barr virus glycoprotein homologous to herpes simplex virus gB. J Virol 1987; 61: 499–508.
-
(1987)
J Virol
, vol.61
, pp. 499-508
-
-
Gong, M.1
Ooka, T.2
Matsuo, T.3
-
124
-
-
0022626625
-
Coronavirus IBV: partial amino terminal sequencing of spike polypeptide S2 identifies the sequence Arg-Arg-Phe-Arg-Arg at the cleavage site of the spike precursor propolypeptide of IBV strains Beaudette and M41
-
Cavanagh D, Davis PJ, Pappin DJ et al. Coronavirus IBV: partial amino terminal sequencing of spike polypeptide S2 identifies the sequence Arg-Arg-Phe-Arg-Arg at the cleavage site of the spike precursor propolypeptide of IBV strains Beaudette and M41. Virus Res 1986; 4: 133–143.
-
(1986)
Virus Res
, vol.4
, pp. 133-143
-
-
Cavanagh, D.1
Davis, P.J.2
Pappin, D.J.3
-
125
-
-
2442680275
-
Cleavage inhibition of the murine coronavirus spike protein by a furin-like enzyme affects cell-cell but not virus-cell fusion
-
de Haan CAM, Stadler K, Godeke G-J et al. Cleavage inhibition of the murine coronavirus spike protein by a furin-like enzyme affects cell-cell but not virus-cell fusion. J Virol 2004; 78: 6048–6054.
-
(2004)
J Virol
, vol.78
, pp. 6048-6054
-
-
de Haan, C.A.M.1
Stadler, K.2
Godeke, G.-J.3
-
126
-
-
0021863828
-
Nucleotide sequence of yellow fever virus: implications for flavivirus gene expression and evolution
-
Rice CM, Lenches EM, Eddy SR et al. Nucleotide sequence of yellow fever virus: implications for flavivirus gene expression and evolution. Science 1985; 229: 726–733.
-
(1985)
Science
, vol.229
, pp. 726-733
-
-
Rice, C.M.1
Lenches, E.M.2
Eddy, S.R.3
-
127
-
-
0030764780
-
Proteolytic activation of tick-borne encephalitis virus by furin
-
Stadler K, Allison SL, Schalich J et al. Proteolytic activation of tick-borne encephalitis virus by furin. J Virol 1997; 71: 8475–8481.
-
(1997)
J Virol
, vol.71
, pp. 8475-8481
-
-
Stadler, K.1
Allison, S.L.2
Schalich, J.3
-
128
-
-
0038212351
-
Nucleotide sequence of the 26S mRNA of Sindbis virus and deduced sequence of the encoded virus structural proteins
-
Rice CM, Strauss JH. Nucleotide sequence of the 26S mRNA of Sindbis virus and deduced sequence of the encoded virus structural proteins. Proc Natl Acad Sci USA 1981; 78: 2062–2066.
-
(1981)
Proc Natl Acad Sci USA
, vol.78
, pp. 2062-2066
-
-
Rice, C.M.1
Strauss, J.H.2
-
129
-
-
0037369080
-
Furin processing and proteolytic activation of Semliki Forest virus
-
Zhang X, Fugère M, Day R et al. Furin processing and proteolytic activation of Semliki Forest virus. J Virol 2003; 77: 2981–2989.
-
(2003)
J Virol
, vol.77
, pp. 2981-2989
-
-
Zhang, X.1
Fugère, M.2
Day, R.3
-
131
-
-
2642647847
-
Processing of the Borna disease virus glycoprotein gp94 by the subtilisin-like endoprotease furin
-
Richt JA, Fürbringer T, Koch A et al. Processing of the Borna disease virus glycoprotein gp94 by the subtilisin-like endoprotease furin. J Virol 1998; 72: 4528–4533.
-
(1998)
J Virol
, vol.72
, pp. 4528-4533
-
-
Richt, J.A.1
Fürbringer, T.2
Koch, A.3
-
132
-
-
33645967164
-
Crimean-Congo hemorrhagic fever virus glycoprotein precursor is cleaved by Furin-like and SKI-1 proteases to generate a novel 38-kilodalton glycoprotein
-
Sanchez AJ, Vincent MJ, Erickson BR et al. Crimean-Congo hemorrhagic fever virus glycoprotein precursor is cleaved by Furin-like and SKI-1 proteases to generate a novel 38-kilodalton glycoprotein. J Virol 2006; 80: 514–525.
-
(2006)
J Virol
, vol.80
, pp. 514-525
-
-
Sanchez, A.J.1
Vincent, M.J.2
Erickson, B.R.3
-
133
-
-
0023212842
-
Molecular analyses of the hemagglutinin genes of H5 influenza viruses: origin of a virulent turkey strain
-
Kawaoka Y, Nestorowicz A, Alexander DJ et al. Molecular analyses of the hemagglutinin genes of H5 influenza viruses: origin of a virulent turkey strain. Virology 1987; 158: 218–227.
-
(1987)
Virology
, vol.158
, pp. 218-227
-
-
Kawaoka, Y.1
Nestorowicz, A.2
Alexander, D.J.3
-
134
-
-
0018600608
-
Complete nucleotide sequence of an influenza virus haemagglutinin gene from cloned DNA
-
Porter AG, Barber C, Carey NH et al. Complete nucleotide sequence of an influenza virus haemagglutinin gene from cloned DNA. Nature 1979; 282: 471–477.
-
(1979)
Nature
, vol.282
, pp. 471-477
-
-
Porter, A.G.1
Barber, C.2
Carey, N.H.3
-
135
-
-
0023235834
-
Structural comparison of the cleavage-activation site of the fusion glycoprotein between virulent and avirulent strains of Newcastle disease virus
-
Toyoda T, Sakaguchi T, Imai K et al. Structural comparison of the cleavage-activation site of the fusion glycoprotein between virulent and avirulent strains of Newcastle disease virus. Virology 1987; 158: 242–247.
-
(1987)
Virology
, vol.158
, pp. 242-247
-
-
Toyoda, T.1
Sakaguchi, T.2
Imai, K.3
-
136
-
-
0022476649
-
Fusion glycoprotein of human parainfluenza virus type 3: nucleotide sequence of the gene, direct identification of the cleavage-activation site, and comparison with other paramyxoviruses
-
Spriggs MK, Olmsted RA, Venkatesan S et al. Fusion glycoprotein of human parainfluenza virus type 3: nucleotide sequence of the gene, direct identification of the cleavage-activation site, and comparison with other paramyxoviruses. Virology 1986; 152: 241–251.
-
(1986)
Virology
, vol.152
, pp. 241-251
-
-
Spriggs, M.K.1
Olmsted, R.A.2
Venkatesan, S.3
-
137
-
-
0023226696
-
Cloning and sequencing of the mumps virus fusion protein gene
-
Waxham MN, Server AC, Goodman HM et al. Cloning and sequencing of the mumps virus fusion protein gene. Virology 1987; 159: 381–388.
-
(1987)
Virology
, vol.159
, pp. 381-388
-
-
Waxham, M.N.1
Server, A.C.2
Goodman, H.M.3
-
138
-
-
0022864334
-
The nucleotide sequence of the mRNA encoding the fusion protein of measles virus (Edmonston strain): a comparison of fusion proteins from several different paramyxoviruses
-
Richardson C, Hull D, Greer P et al. The nucleotide sequence of the mRNA encoding the fusion protein of measles virus (Edmonston strain): a comparison of fusion proteins from several different paramyxoviruses. Virology 1986; 155: 508–523.
-
(1986)
Virology
, vol.155
, pp. 508-523
-
-
Richardson, C.1
Hull, D.2
Greer, P.3
-
139
-
-
0344919162
-
Fusion protein of the paramyxovirus simian virus 5: nucleotide sequence of mRNA predicts a highly hydrophobic glycoprotein
-
Paterson RG, Harris TJ, Lamb RA. Fusion protein of the paramyxovirus simian virus 5: nucleotide sequence of mRNA predicts a highly hydrophobic glycoprotein. Proc Natl Acad Sci USA 1984; 81: 6706–6710.
-
(1984)
Proc Natl Acad Sci USA
, vol.81
, pp. 6706-6710
-
-
Paterson, R.G.1
Harris, T.J.2
Lamb, R.A.3
-
140
-
-
0021742698
-
Nucleotide sequence of the gene encoding the fusion (F) glycoprotein of human respiratory syncytial virus
-
Collins PL, Huang YT, Wertz GW. Nucleotide sequence of the gene encoding the fusion (F) glycoprotein of human respiratory syncytial virus. Proc Natl Acad Sci USA 1984; 81: 7683–7687.
-
(1984)
Proc Natl Acad Sci USA
, vol.81
, pp. 7683-7687
-
-
Collins, P.L.1
Huang, Y.T.2
Wertz, G.W.3
-
141
-
-
0023921610
-
Endoproteolytic cleavage of gp160 is required for the activation of human immunodeficiency virus
-
McCune JM, Rabin LB, Feinberg MB et al. Endoproteolytic cleavage of gp160 is required for the activation of human immunodeficiency virus. Cell 1988; 53: 55–67.
-
(1988)
Cell
, vol.53
, pp. 55-67
-
-
McCune, J.M.1
Rabin, L.B.2
Feinberg, M.B.3
-
142
-
-
0022252943
-
Structural characterization of the avian retrovirus reverse transcriptase and endonuclease domains
-
Grandgenett D, Quinn T, Hippenmeyer PJ et al. Structural characterization of the avian retrovirus reverse transcriptase and endonuclease domains. J Biol Chem 1985; 260: 8243–8249.
-
(1985)
J Biol Chem
, vol.260
, pp. 8243-8249
-
-
Grandgenett, D.1
Quinn, T.2
Hippenmeyer, P.J.3
-
143
-
-
0023199650
-
The role of envelope glycoprotein processing in murine leukemia virus infection
-
Freed EO, Risser R. The role of envelope glycoprotein processing in murine leukemia virus infection. J Virol 1987; 61: 2852–2856.
-
(1987)
J Virol
, vol.61
, pp. 2852-2856
-
-
Freed, E.O.1
Risser, R.2
-
144
-
-
10044260072
-
Furin-mediated cleavage of the feline foamy virus Env leader protein
-
Geiselhart V, Bastone P, Kempf T et al. Furin-mediated cleavage of the feline foamy virus Env leader protein. J Virol 2004; 78: 13573–13581.
-
(2004)
J Virol
, vol.78
, pp. 13573-13581
-
-
Geiselhart, V.1
Bastone, P.2
Kempf, T.3
|