Generation and characterization of non-competitive furin-inhibiting nanobodies

Biochemical Journal

Volumn 448, Issue 1, 2012, Pages 73-82

  Zhu, Jingjing ^a   Declercq, Jeroen ^a   Roucourt, Bart ^a   Ghassabeh, Gholamreza H ^b,c   Meulemans, Sandra ^a   Kinne, Jörg ^d   David, Guido ^a   Vermorken, Alphons J M ^a   Van De Ven, Wim J M ^e   Lindberg, Iris ^f   Muyldermans, Serge ^b,c   Creemers, John W M ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

^c DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^d CENTRAL VETERINARY RESEARCH LABORATORY   (United Arab Emirates)

^e FLORIDA ATLANTIC UNIVERSITY   (United States)

^f UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

Diphtheria toxin; Furin; Nanobody; Proprotein convertase

Indexed keywords

DIPHTHERIA TOXIN; FURIN; GLYPICAN 3; IMMUNOGLOBULIN HEAVY CHAIN; NANOBODY; NANOMATERIAL; PROPROTEIN CONVERTASE 1; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; DNA ISOLATION; DROMEDARY; FEMALE; GENE OVEREXPRESSION; IMMUNE RESPONSE; IMMUNIZATION; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ANTIBODY SPECIFICITY; CAMELS; CATALYSIS; COUMARINS; DIPHTHERIA TOXIN; ENDOCYTOSIS; FURIN; GLYPICANS; HEK293 CELLS; HUMANS; KINETICS; MICE; OLIGOPEPTIDES; PEPTIDE FRAGMENTS; PROPROTEIN CONVERTASES; PROTEIN BINDING; SINGLE-DOMAIN ANTIBODIES; SUBSTRATE SPECIFICITY; TRANSFORMING GROWTH FACTOR BETA;

EID: 84867762574     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20120537     Document Type: Article

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