메뉴 건너뛰기




Volumn 108, Issue 3, 2006, Pages 983-985

Proprotein convertase furin is preferentially expressed in T helper 1 cells and regulates interferon gamma

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; FURIN; GAMMA INTERFERON; INTERLEUKIN 12; SERINE PROTEINASE; STAT PROTEIN; STAT4 PROTEIN;

EID: 33746600246     PISSN: 00064971     EISSN: 00064971     Source Type: Journal    
DOI: 10.1182/blood-2005-09-3824     Document Type: Article
Times cited : (66)

References (24)
  • 1
    • 0030002111 scopus 로고    scopus 로고
    • Genetically resistant mice lacking interleukin-12 are susceptible to infection with Leishmania major and mount a polarized Th2 cell response
    • Mattner F, Magram J, Ferrante J, et al. Genetically resistant mice lacking interleukin-12 are susceptible to infection with Leishmania major and mount a polarized Th2 cell response. Eur J Immunol. 1996;26:1553-1559.
    • (1996) Eur J Immunol , vol.26 , pp. 1553-1559
    • Mattner, F.1    Magram, J.2    Ferrante, J.3
  • 2
    • 0031571205 scopus 로고    scopus 로고
    • Characterization of IL-12 receptor beta1 chain (IL-12Rbeta1)-deficient mice: IL-12Rbeta1 is an essential component of the functional mouse IL-12 receptor
    • Wu C, Ferrante J, Gately MK, Magram J. Characterization of IL-12 receptor beta1 chain (IL-12Rbeta1)-deficient mice: IL-12Rbeta1 is an essential component of the functional mouse IL-12 receptor. J Immunol. 1997;159:1658-1665.
    • (1997) J Immunol , vol.159 , pp. 1658-1665
    • Wu, C.1    Ferrante, J.2    Gately, M.K.3    Magram, J.4
  • 3
    • 0027464928 scopus 로고
    • Immune response in mice that lack the interferon-gamma receptor
    • Huang S, Hendriks W, Althage A, et al. Immune response in mice that lack the interferon-gamma receptor. Science. 1993;259:1742-1745.
    • (1993) Science , vol.259 , pp. 1742-1745
    • Huang, S.1    Hendriks, W.2    Althage, A.3
  • 4
    • 0027400726 scopus 로고
    • Multiple defects of immune cell function in mice with disrupted interferon-gamma genes
    • Dalton DK, Pitts-Meek S, Keshav S, Figari IS, Bradley A, Stewart TA. Multiple defects of immune cell function in mice with disrupted interferon-gamma genes. Science. 1993;259:1739-1742.
    • (1993) Science , vol.259 , pp. 1739-1742
    • Dalton, D.K.1    Pitts-Meek, S.2    Keshav, S.3    Figari, I.S.4    Bradley, A.5    Stewart, T.A.6
  • 5
    • 0036219062 scopus 로고    scopus 로고
    • Genetic dissection of immunity to mycobacteria: The human model
    • Casanova JL, Abel L. Genetic dissection of immunity to mycobacteria: the human model. Annu Rev Immunol. 2002;20:581-620.
    • (2002) Annu Rev Immunol , vol.20 , pp. 581-620
    • Casanova, J.L.1    Abel, L.2
  • 7
    • 0029937270 scopus 로고    scopus 로고
    • Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice
    • Kaplan MH, Sun YL, Hoey T, Grusby MJ. Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice. Nature. 1996;382:174-177.
    • (1996) Nature , vol.382 , pp. 174-177
    • Kaplan, M.H.1    Sun, Y.L.2    Hoey, T.3    Grusby, M.J.4
  • 8
    • 0034075845 scopus 로고    scopus 로고
    • Transcript imaging of the development of human T helper cells using oligonucleotide arrays
    • Rogge L, Bianchi E, Biffi M, et al. Transcript imaging of the development of human T helper cells using oligonucleotide arrays. Nat Genet. 2000;25:96-101.
    • (2000) Nat Genet , vol.25 , pp. 96-101
    • Rogge, L.1    Bianchi, E.2    Biffi, M.3
  • 9
    • 0042466572 scopus 로고    scopus 로고
    • Distinct requirements for the naturally occurring splice forms Stat4alpha and Stat4beta in IL-12 responses
    • Hoey T, Zhang S, Schmidt N, et al. Distinct requirements for the naturally occurring splice forms Stat4alpha and Stat4beta in IL-12 responses. EMBO J. 2003;22:4237-4248.
    • (2003) EMBO J , vol.22 , pp. 4237-4248
    • Hoey, T.1    Zhang, S.2    Schmidt, N.3
  • 10
    • 2442711457 scopus 로고    scopus 로고
    • Early target genes of IL-12 and STAT4 signaling in Th cells
    • Lund RJ, Chen Z, Scheinin J, Lahesmaa R. Early target genes of IL-12 and STAT4 signaling in Th cells. J Immunol. 2004;172:6775-6782.
    • (2004) J Immunol , vol.172 , pp. 6775-6782
    • Lund, R.J.1    Chen, Z.2    Scheinin, J.3    Lahesmaa, R.4
  • 11
    • 1542327676 scopus 로고    scopus 로고
    • Kinetic analysis of genomewide gene expression reveals molecule circuitries that control T cell activation and Th1/2 differentiation
    • Lu B, Zagouras P, Fischer JE, Lu J, Li B, Flavell RA. Kinetic analysis of genomewide gene expression reveals molecule circuitries that control T cell activation and Th1/2 differentiation. Proc Natl Acad Sci U S A. 2004;101:3023-3028.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 3023-3028
    • Lu, B.1    Zagouras, P.2    Fischer, J.E.3    Lu, J.4    Li, B.5    Flavell, R.A.6
  • 12
    • 0033564574 scopus 로고    scopus 로고
    • IL-12 induces IFN regulating factor-1 (IRF-1) gene expression in human NK and T cells
    • Galon J, Sudarshan C, Ito S, Finbloom D, O'Shea JJ. IL-12 induces IFN regulating factor-1 (IRF-1) gene expression in human NK and T cells. J Immunol. 1999;162:7256-7262.
    • (1999) J Immunol , vol.162 , pp. 7256-7262
    • Galon, J.1    Sudarshan, C.2    Ito, S.3    Finbloom, D.4    O'Shea, J.J.5
  • 13
    • 0029116336 scopus 로고
    • Interleukin 12 induces tyrosine phosphorylation and activation of STAT4 in human lymphocytes
    • Bacon CM, Petricoin EF 3rd, Ortaldo JR, et al. Interleukin 12 induces tyrosine phosphorylation and activation of STAT4 in human lymphocytes. Proc Natl Acad Sci U S A. 1995;92:7307-7311.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 7307-7311
    • Bacon, C.M.1    Petricoin III, E.F.2    Ortaldo, J.R.3
  • 14
    • 4644320690 scopus 로고    scopus 로고
    • Discrete roles for histone acetylation in human T helper 1 cell-specific gene expression
    • Morinobu A, Kanno Y, O'Shea JJ. Discrete roles for histone acetylation in human T helper 1 cell-specific gene expression. J Biol Chem. 2004;279:40640-40646.
    • (2004) J Biol Chem , vol.279 , pp. 40640-40646
    • Morinobu, A.1    Kanno, Y.2    O'Shea, J.J.3
  • 15
    • 0034650951 scopus 로고    scopus 로고
    • Interleukin-4-induced transcriptional activation by stat6 involves multiple serine/threonine kinase pathways and serine phosphorylation of stat6
    • Pesu M, Takaluoma K, Aittomaki S, et al. Interleukin-4-induced transcriptional activation by stat6 involves multiple serine/threonine kinase pathways and serine phosphorylation of stat6. Blood. 2000;95:494-502.
    • (2000) Blood , vol.95 , pp. 494-502
    • Pesu, M.1    Takaluoma, K.2    Aittomaki, S.3
  • 16
    • 0036791359 scopus 로고    scopus 로고
    • Furin at the cutting edge: From protein traffic to embryogenesis and disease
    • Thomas G. Furin at the cutting edge: from protein traffic to embryogenesis and disease. Nat Rev Mol Cell Biol. 2002;3:753-766.
    • (2002) Nat Rev Mol Cell Biol , vol.3 , pp. 753-766
    • Thomas, G.1
  • 17
    • 0028815633 scopus 로고
    • A second mutant allele of furin in the processing-incompetent cell line, LoVo: Evidence for involvement of the homo B domain in autocatalytic activation
    • Takahashi S, Nakagawa T, Kasai K, et al. A second mutant allele of furin in the processing-incompetent cell line, LoVo: evidence for involvement of the homo B domain in autocatalytic activation. J Biol Chem. 1995;270:26565-26569.
    • (1995) J Biol Chem , vol.270 , pp. 26565-26569
    • Takahashi, S.1    Nakagawa, T.2    Kasai, K.3
  • 19
    • 0027429771 scopus 로고
    • Inhibition of HIV-1 gp160-dependent membrane fusion by a furin-directed alpha 1-antitrypsin variant
    • Anderson ED, Thomas L, Hayflick JS, Thomas G. Inhibition of HIV-1 gp160-dependent membrane fusion by a furin-directed alpha 1-antitrypsin variant. J Biol Chem. 1993;268:24887-24891.
    • (1993) J Biol Chem , vol.268 , pp. 24887-24891
    • Anderson, E.D.1    Thomas, L.2    Hayflick, J.S.3    Thomas, G.4
  • 20
    • 0032560449 scopus 로고    scopus 로고
    • alpha1-Antitrypsin Portland, a bioengineered serpin highly selective for furin: Application as an antipathogenic agent
    • Jean F, Stella K, Thomas L, et al. alpha1-Antitrypsin Portland, a bioengineered serpin highly selective for furin: application as an antipathogenic agent. Proc Natl Acad Sci U S A. 1998;95:7293-7298.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 7293-7298
    • Jean, F.1    Stella, K.2    Thomas, L.3
  • 21
    • 0034646199 scopus 로고    scopus 로고
    • A protein-based therapeutic for human cytomegalovirus infection
    • Jean F, Thomas L, Molloy SS, et al. A protein-based therapeutic for human cytomegalovirus infection. Proc Natl Acad Sci U S A. 2000;97:2864-2869.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 2864-2869
    • Jean, F.1    Thomas, L.2    Molloy, S.S.3
  • 22
    • 0842313260 scopus 로고    scopus 로고
    • Prediction of proprotein convertase cleavage sites
    • Duckert P, Brunak S, Blom N. Prediction of proprotein convertase cleavage sites. Protein Eng Des Sel. 2004;17:107-112.
    • (2004) Protein Eng des Sel , vol.17 , pp. 107-112
    • Duckert, P.1    Brunak, S.2    Blom, N.3
  • 23
    • 0032443652 scopus 로고    scopus 로고
    • Failure of ventral closure and axial rotation in embryos lacking the proprotein convertase Furin
    • Roebroek AJ, Umans L, Pauli IG, et al. Failure of ventral closure and axial rotation in embryos lacking the proprotein convertase Furin. Development. 1998;125:4863-4876.
    • (1998) Development , vol.125 , pp. 4863-4876
    • Roebroek, A.J.1    Umans, L.2    Pauli, I.G.3
  • 24
    • 19944414287 scopus 로고    scopus 로고
    • Limited redundancy of the proprotein convertase furin in mouse liver
    • Roebroek AJ, Taylor NA, Louagie E, et al. Limited redundancy of the proprotein convertase furin in mouse liver. J Biol Chem. 2004;279:53442-53450.
    • (2004) J Biol Chem , vol.279 , pp. 53442-53450
    • Roebroek, A.J.1    Taylor, N.A.2    Louagie, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.