Influenza virus activating host proteases: Identification, localization and inhibitors as potential therapeutics

European Journal of Cell Biology

Volumn 94, Issue 7-9, 2015, Pages 375-383

  Garten, Wolfgang ^a   Braden, Carolin ^a   Arendt, Annika ^a   Peitsch, Catharina ^a   Baron, Joanna ^a   Lu, Yinghui ^a   Pawletko, Kerstin ^a   Hardes, Kornelia ^a   Steinmetzer, Torsten ^a   Böttcher Friebertshäuser, Eva ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

Cellular host proteases; Compartimentalization of proteases; Protease inhibitors as antivirals; Proteolytic activation of influenza viruses

Indexed keywords

4 ACETAMIDO 5 AMINO 3 (1 ETHYLPROPOXY) 1 CYCLOHEXENE 1 CARBOXYLIC ACID; AMINO ACID; AMINOCAPROIC ACID; ANTIVIRUS AGENT; APROTININ; ARGININE; FAVIPIRAVIR; FURIN; INFLUENZA VIRUS HEMAGGLUTININ; MI 001; MI 432; MI 701; OSELTAMIVIR; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROPROTEIN CONVERTASE 5; PROPROTEIN CONVERTASE 6; PROTEINASE; PROTEINASE INHIBITOR; RIBAVIRIN; SERINE PROTEINASE; SERINE PROTEINASE INHIBITOR; SUBTILASE; TRANSMEMBRANE PROTEASE SERINE 2; TRYPTASE; UNCLASSIFIED DRUG; HUMAN AIRWAY TRYPSIN-LIKE PROTEASE; TMPRSS2 PROTEIN, HUMAN; TMPRSS2 PROTEIN, MOUSE;

AVIAN INFLUENZA VIRUS; BIOSYNTHESIS; CELLULAR DISTRIBUTION; DRUG EFFECT; ENZYME INHIBITION; ENZYME LOCALIZATION; EPITHELIUM; HUMAN; INFLUENZA; INFLUENZA VIRUS; INFLUENZA VIRUS A H1N1; INFLUENZA VIRUS A H3N2; INFLUENZA VIRUS A H7N9; NONHUMAN; PATHOGENICITY; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN MOTIF; RESPIRATORY SYSTEM; SHORT SURVEY; TRANS GOLGI NETWORK; VIRUS GENOME; ANIMAL; GENETICS; INFLUENZA A VIRUS (H1N1); INFLUENZA A VIRUS (H3N2); INFLUENZA A VIRUS (H7N9); METABOLISM; MOUSE; ORTHOMYXOVIRUS INFECTION; PATHOLOGY; RESPIRATORY TRACT MUCOSA; VIROLOGY;

AVES; EUKARYOTA; MUS; ORTHOMYXOVIRIDAE;

ANIMALS; FURIN; HEMAGGLUTININ GLYCOPROTEINS, INFLUENZA VIRUS; HUMANS; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA A VIRUS, H3N2 SUBTYPE; INFLUENZA A VIRUS, H7N9 SUBTYPE; INFLUENZA, HUMAN; MICE; ORTHOMYXOVIRIDAE INFECTIONS; PROPROTEIN CONVERTASE 5; RESPIRATORY MUCOSA; SERINE ENDOPEPTIDASES; SERINE PROTEASES; TRANS-GOLGI NETWORK;

EID: 84939654675     PISSN: 01719335     EISSN: 16181298     Source Type: Journal    
DOI: 10.1016/j.ejcb.2015.05.013     Document Type: Short Survey

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