-
1
-
-
0033452452
-
Proprotein and prohormone convertases: A family of subtilases generating diverse bioactive polypeptides
-
Seidah NG, Chretien M. Proprotein and prohormone convertases: a family of subtilases generating diverse bioactive polypeptides. Brain Res 1999;848:45-62.
-
(1999)
Brain Res
, vol.848
, pp. 45-62
-
-
Seidah, N.G.1
Chretien, M.2
-
2
-
-
0036083664
-
Proprotein convertases in tumor progression and malignancy: Novel targets in cancer therapy
-
Khatib AM, Siegfried G, Chretien M, Metrakos P, Seidah NG. Proprotein convertases in tumor progression and malignancy: novel targets in cancer therapy. Am J Pathol 2002;160:1921-35.
-
(2002)
Am J Pathol
, vol.160
, pp. 1921-1935
-
-
Khatib, A.M.1
Siegfried, G.2
Chretien, M.3
Metrakos, P.4
Seidah, N.G.5
-
3
-
-
34548019745
-
Potential opportunity in the development of new therapeutic agents based on endogenous and exogenous inhibitors of the proprotein convertases
-
Bontemps Y, Scamuffa N, Calvo F, Khatib AM. Potential opportunity in the development of new therapeutic agents based on endogenous and exogenous inhibitors of the proprotein convertases. Med Res Rev 2007;27:631-48.
-
(2007)
Med Res Rev
, vol.27
, pp. 631-648
-
-
Bontemps, Y.1
Scamuffa, N.2
Calvo, F.3
Khatib, A.M.4
-
4
-
-
27744541223
-
Inhibitors of proprotein convertases
-
Basak A. Inhibitors of proprotein convertases. J Mol Med 2005;83:844-55.
-
(2005)
J Mol Med
, vol.83
, pp. 844-855
-
-
Basak, A.1
-
5
-
-
0037379743
-
The proteolytic processing of pro-platelet-derived growth factor-A at RRKR(86) by members of the proprotein convertase family is functionally correlated to platelet-derived growth factor-A-induced functions and tumorigenicity
-
Siegfried G, Khatib AM, Benjannet S, Chretien M, Seidah NG. The proteolytic processing of pro-platelet-derived growth factor-A at RRKR(86) by members of the proprotein convertase family is functionally correlated to platelet-derived growth factor-A-induced functions and tumorigenicity. Cancer Res 2003;63:1458-63.
-
(2003)
Cancer Res
, vol.63
, pp. 1458-1463
-
-
Siegfried, G.1
Khatib, A.M.2
Benjannet, S.3
Chretien, M.4
Seidah, N.G.5
-
6
-
-
27144488288
-
Regulation of the stepwise proteolytic cleavage and secretion of PDGF-B by the proprotein convertases
-
Siegfried G, Basak A, Prichett-Pejic W, et al. Regulation of the stepwise proteolytic cleavage and secretion of PDGF-B by the proprotein convertases. Oncogene 2005;24:6925-35.
-
(2005)
Oncogene
, vol.24
, pp. 6925-6935
-
-
Siegfried, G.1
Basak, A.2
Prichett-Pejic, W.3
-
7
-
-
0038481179
-
The secretory proprotein convertases furin, PC5, and PC7 activate VEGF-C to induce tumorigenesis
-
Siegfried G, Basak A, Cromlish JA, et al. The secretory proprotein convertases furin, PC5, and PC7 activate VEGF-C to induce tumorigenesis. J Clin Invest 2003;111:1723-32.
-
(2003)
J Clin Invest
, vol.111
, pp. 1723-1732
-
-
Siegfried, G.1
Basak, A.2
Cromlish, J.A.3
-
8
-
-
0035903230
-
Inhibition of proprotein convertases is associated with loss of growth and tumorigenicity of HT-29 human colon carcinoma cells: Importance of insulin-like growth factor-1 (IGF-1) receptor processing in IGF-1-mediated functions
-
Khatib AM, Siegfried G, Prat A, Luis J, Chretien M, Metrakos P, Seidah NG. Inhibition of proprotein convertases is associated with loss of growth and tumorigenicity of HT-29 human colon carcinoma cells: importance of insulin-like growth factor-1 (IGF-1) receptor processing in IGF-1-mediated functions. J Biol Chem 2001;276:30686-93.
-
(2001)
J Biol Chem
, vol.276
, pp. 30686-30693
-
-
Khatib, A.M.1
Siegfried, G.2
Prat, A.3
Luis, J.4
Chretien, M.5
Metrakos, P.6
Seidah, N.G.7
-
9
-
-
0032560449
-
a1-Antitrypsin Portland, a bioengineered serpin highly selective for furin: Application as an antipathogenic agent
-
Jean F, Stella K, Thomas L, et al. a1-Antitrypsin Portland, a bioengineered serpin highly selective for furin: application as an antipathogenic agent. Proc Natl Acad Sci U S A 1998;95:7293-8.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 7293-7298
-
-
Jean, F.1
Stella, K.2
Thomas, L.3
-
10
-
-
0030982225
-
Pro-protein convertase gene expression in human breast cancer
-
Cheng M, Watson PH, Paterson JA, Seidah N, Chretien M, Shiu RP. Pro-protein convertase gene expression in human breast cancer. Int J Cancer 1997;71:966-71.
-
(1997)
Int J Cancer
, vol.71
, pp. 966-971
-
-
Cheng, M.1
Watson, P.H.2
Paterson, J.A.3
Seidah, N.4
Chretien, M.5
Shiu, R.P.6
-
11
-
-
0034467122
-
Metalloproteinases: Role in breast carcinogenesis, invasion and metastasis
-
Duffy MJ, Maguire TM, Hill A, McDermott E, O'Higgins N. Metalloproteinases: role in breast carcinogenesis, invasion and metastasis. Breast Cancer Res 2000;2:252-7.
-
(2000)
Breast Cancer Res
, vol.2
, pp. 252-257
-
-
Duffy, M.J.1
Maguire, T.M.2
Hill, A.3
McDermott, E.4
O'Higgins, N.5
-
12
-
-
0033607676
-
The prosegments of furin and PC7 as potent inhibitors of proprotein convertases. In vitro and ex vivo assessment of their efficacy and selectivity
-
Zhong M, Munzer JS, Basak A, et al. The prosegments of furin and PC7 as potent inhibitors of proprotein convertases. In vitro and ex vivo assessment of their efficacy and selectivity. J Biol Chem 1999;274:33913-20.
-
(1999)
J Biol Chem
, vol.274
, pp. 33913-33920
-
-
Zhong, M.1
Munzer, J.S.2
Basak, A.3
-
13
-
-
0037474310
-
Structure-function analysis of the prosegment of the proprotein convertase PC5A
-
Nour N, Basak A, Chretien M, Seidah NG. Structure-function analysis of the prosegment of the proprotein convertase PC5A. J Biol Chem 2003;278:2886-95.
-
(2003)
J Biol Chem
, vol.278
, pp. 2886-2895
-
-
Nour, N.1
Basak, A.2
Chretien, M.3
Seidah, N.G.4
-
14
-
-
0034846315
-
Elevated furin expression in aggressive human head and neck tumors and tumor cell lines
-
Bassi DE, Mahloogi H, Al-Saleem L, Lopez De Cicco R, Ridge JA, Klein-Szanto AJ. Elevated furin expression in aggressive human head and neck tumors and tumor cell lines. Mol Carcinog 2001;31:224-32.
-
(2001)
Mol Carcinog
, vol.31
, pp. 224-232
-
-
Bassi, D.E.1
Mahloogi, H.2
Al-Saleem, L.3
Lopez De Cicco, R.4
Ridge, J.A.5
Klein-Szanto, A.J.6
-
15
-
-
0038792251
-
Epigenetic regulation of proprotein convertase PACE4 gene expression in human ovarian cancer cells
-
Fu Y, Campbell EJ, Shepherd TG, Nachtigal MW. Epigenetic regulation of proprotein convertase PACE4 gene expression in human ovarian cancer cells. Mol Cancer Res 2003;1:569-76.
-
(2003)
Mol Cancer Res
, vol.1
, pp. 569-576
-
-
Fu, Y.1
Campbell, E.J.2
Shepherd, T.G.3
Nachtigal, M.W.4
-
16
-
-
0035964398
-
Furin inhibition results in absent or decreased invasiveness and tumorigenicity of human cancer cells
-
Bassi DE, Lopez De Cicco R, Mahloogi H, Zucker S, Thomas G, Klein-Szanto AJ. Furin inhibition results in absent or decreased invasiveness and tumorigenicity of human cancer cells. Proc Natl Acad Sci U S A 2001;98:10326-31.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 10326-10331
-
-
Bassi, D.E.1
Lopez De Cicco, R.2
Mahloogi, H.3
Zucker, S.4
Thomas, G.5
Klein-Szanto, A.J.6
-
17
-
-
2442664240
-
Inhibition of proprotein convertases enhances cell migration and metastases development of human colon carcinoma cells in a rat model
-
Nejjari M, Berthet V, Rigot V, et al. Inhibition of proprotein convertases enhances cell migration and metastases development of human colon carcinoma cells in a rat model. Am J Pathol 2004;164:1925-33.
-
(2004)
Am J Pathol
, vol.164
, pp. 1925-1933
-
-
Nejjari, M.1
Berthet, V.2
Rigot, V.3
-
18
-
-
20144371230
-
Human carcinoma cell growth and invasiveness is impaired by the propeptide of the ubiquitous proprotein convertase furin
-
Lopez de Cicco R, Bassi DE, Zucker S, Seidah NG, Klein-Szanto AJ. Human carcinoma cell growth and invasiveness is impaired by the propeptide of the ubiquitous proprotein convertase furin. Cancer Res 2005;65:4162-71.
-
(2005)
Cancer Res
, vol.65
, pp. 4162-4171
-
-
Lopez de Cicco, R.1
Bassi, D.E.2
Zucker, S.3
Seidah, N.G.4
Klein-Szanto, A.J.5
-
19
-
-
0037332088
-
Increased furin activity enhances the malignant phenotype of human head and neck cancer cells
-
Bassi DE, Mahloogi H, Lopez De Cicco R, Klein-Szanto A. Increased furin activity enhances the malignant phenotype of human head and neck cancer cells. Am J Pathol 2003;162:439-47.
-
(2003)
Am J Pathol
, vol.162
, pp. 439-447
-
-
Bassi, D.E.1
Mahloogi, H.2
Lopez De Cicco, R.3
Klein-Szanto, A.4
-
20
-
-
0036252564
-
Malignant conversion of non-tumorigenic murine skin keratinocytes overexpressing PACE4
-
Mahloogi H, Bassi DE, Klein-Szanto AJ. Malignant conversion of non-tumorigenic murine skin keratinocytes overexpressing PACE4. Carcinogenesis 2002;23:565-72.
-
(2002)
Carcinogenesis
, vol.23
, pp. 565-572
-
-
Mahloogi, H.1
Bassi, D.E.2
Klein-Szanto, A.J.3
|