Differential modulation of prM cleavage, extracellular particle distribution, and virus infectivity by conserved residues at nonfurin consensus positions of the dengue virus pr-M junction

Journal of Virology

Volumn 82, Issue 21, 2008, Pages 10776-10791

  Junjhon, Jiraphan ^a   Lausumpao, Matthawee ^a   Supasa, Sunpetchuda ^a   Noisakran, Sansanee ^b   Songjaeng, Adisak ^a   Saraithong, Prakaimuk ^a   Chaichoun, Kridsada ^a   Utaipat, Utaiwan ^c   Keelapang, Poonsook ^a   Kanjanahaluethai, Amornrat ^a   Puttikhunt, Chunya ^b   Kasinrerk, Watchara ^b,c   Malasit, Prida ^b,d   Sittisombut, Nopporn ^a,b  

^a Faculty of Medicine Chiang Mai University   (Thailand)

^b NATIONAL SCIENCE AND TECHNOLOGY DEVELOPMENT AGENCY   (Thailand)

^c CHIANG MAI UNIVERSITY   (Thailand)

^d MAHIDOL UNIVERSITY   (Thailand)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; ARGININE; CHIMERIC PROTEIN; FURIN; GLUTAMIC ACID; HISTIDINE; MUTANT PROTEIN; PROTEIN PRM; STRUCTURAL PROTEIN; UNCLASSIFIED DRUG; VIRUS PROTEIN; PRM PROTEIN, FLAVIVIRUS; VIRUS ENVELOPE PROTEIN;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DENGUE VIRUS; EXTRACELLULAR SPACE; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; VIRION; VIRUS INFECTIVITY; VIRUS PARTICLE; VIRUS REPLICATION; AMINO ACID SUBSTITUTION; ANIMAL; BINDING SITE; CELL LINE; GENETICS; METABOLISM; MOLECULAR GENETICS; MOSQUITO; PHYSIOLOGY; SITE DIRECTED MUTAGENESIS; TRANSMISSION ELECTRON MICROSCOPY; ULTRASTRUCTURE; VIRUS ASSEMBLY;

DENGUE VIRUS; FLAVIVIRUS;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; BINDING SITES; CELL LINE; CULICIDAE; DENGUE VIRUS; FURIN; MICROSCOPY, ELECTRON, TRANSMISSION; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; POINT MUTATION; VIRAL ENVELOPE PROTEINS; VIRION; VIRUS ASSEMBLY;

EID: 55249088356     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.01180-08     Document Type: Article

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