Regnase-1 and roquin nonredundantly regulate Th1 differentiation causing cardiac inflammation and fibrosis

Journal of Immunology

Volumn 199, Issue 12, 2017, Pages 4066-4077

  Cui, Xiaotong ^a,b   Mino, Takashi ^a   Yoshinaga, Masanori ^a   Nakatsuka, Yoshinari ^a   Hia, Fabian ^a   Yamasoba, Daichi ^a   Tsujimura, Tohru ^c   Tomonaga, Keizo ^a,b   Suzuki, Yutaka ^d   Uehata, Takuya ^a   Takeuchi, Osamu ^a  

^a KYOTO UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c HYOGO COLLEGE OF MEDICINE   (Japan)

^d UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

FURIN; GAMMA INTERFERON RECEPTOR; INTERLEUKIN 12 RECEPTOR BETA1; INTERLEUKIN 17; INTERLEUKIN 4; MESSENGER RNA; REGNASE 1; RNA BINDING PROTEIN; ROQUIN; UNCLASSIFIED DRUG; GAMMA INTERFERON; HYBRID PROTEIN; IL12RB1 PROTEIN, MOUSE; INTERLEUKIN 12 RECEPTOR; RC3H1 PROTEIN, MOUSE; RIBONUCLEASE; UBIQUITIN PROTEIN LIGASE; ZC3H12A PROTEIN, MOUSE;

3' UNTRANSLATED REGION; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CARDITIS; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE SEVERITY; DOWN REGULATION; HEART MUSCLE FIBROSIS; LYMPHOCYTE ACTIVATION; LYMPHOCYTE DIFFERENTIATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; TH1 CELL; TH17 CELL; TH2 CELL; UPREGULATION; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CARDIAC MUSCLE; CYTOLOGY; DEFICIENCY; FIBROSIS; GENE EXPRESSION REGULATION; GENETICS; GERMFREE ANIMAL; HELA CELL LINE; HOMEOSTASIS; HUMAN; IMMUNOLOGY; JURKAT CELL LINE; KNOCKOUT MOUSE; LYMPHOPOIESIS; METABOLISM; MUTANT MOUSE STRAIN; MYOCARDITIS; PATHOLOGY; PHYSIOLOGY; SPLEEN;

3' UNTRANSLATED REGIONS; ANIMALS; FIBROSIS; FURIN; GENE EXPRESSION REGULATION; HELA CELLS; HOMEOSTASIS; HUMANS; INTERFERON-GAMMA; INTERLEUKIN-17; INTERLEUKIN-4; JURKAT CELLS; LYMPHOCYTE ACTIVATION; LYMPHOPOIESIS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, MUTANT STRAINS; MYOCARDITIS; MYOCARDIUM; RECEPTORS, INTERLEUKIN-12; RECOMBINANT FUSION PROTEINS; RIBONUCLEASES; RNA, MESSENGER; SPECIFIC PATHOGEN-FREE ORGANISMS; SPLEEN; TH1 CELLS; UBIQUITIN-PROTEIN LIGASES;

EID: 85038587128     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1701211     Document Type: Article

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