Severe influenza pneumonitis in children with inherited TLR3 deficiency

Journal of Experimental Medicine

Volumn 216, Issue 9, 2019, Pages 2038-2056

  Lim, Hye Kyung ^a,b,c   Huang, Sarah X L ^d,e   Chen, Jie ^a,f   Kerner, Gaspard ^b,c   Gilliaux, Olivier ^g,h   Bastard, Paul ^b,c   Dobbs, Kerry ⁱ   Hernandez, Nicholas ^a   Goudin, Nicolas ^j   Hasek, Mary L ^a   Reino, Eduardo Javier García ^a   Lafaille, Fabien G ^a   Lorenzo, Lazaro ^b,c   Luthra, Priya ^k   Kochetkov, Tatiana ^a   Bigio, Benedetta ^a   Boucherit, Soraya ^b,c   Rozenberg, Flore ^l   Vedrinne, Catherine ^m   Keller, Michael D ⁿ   Itan, Yuval ^a,k   García Sastre, Adolfo ^k   Celard, Marie ^o   Orange, Jordan S ^p   Ciancanelli, Michael J ^a   Meyts, Isabelle ^k,q,r   Zhang, Qian ^a   Abel, Laurent ^a,b,c   Notarangelo, Luigi D ⁱ   Snoeck, Hans Willem ^d   Casanova, Jean Laurent ^a,b,c,s,t   Zhang, Shen Ying ^a,b,c   more..

^a ROCKEFELLER UNIVERSITY   (United States)

^b IMAGINE INSTITUTE   (France)

^c UNIVERSITÉ PARIS DESCARTES   (France)

^d NewYork Presbyterian Hospital   (United States)

^e UNIVERSITY OF TEXAS   (United States)

^f SHANGHAI JIAO TONG UNIVERSITY   (China)

^g UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^h Centre Hospitalier Universitaire de Charleroi   (Belgium)

ⁱ NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^j INSERM   (France)

^k MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^l Paris Descartes University ^*  (France)

^m LOUIS PRADEL HOSPITAL   (France)

ⁿ CHILDREN'S NATIONAL MEDICAL CENTER   (United States)

^o Lyon Public Hospitals   (France)

^p BAYLOR COLLEGE OF MEDICINE   (United States)

^q UNIVERSITY OF LEUVEN   (Belgium)

^r UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^s HÔPITAL NECKER ENFANTS MALADES   (France)

^t HOWARD HUGHES MEDICAL INSTITUTE   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; BETA INTERFERON; DOUBLE STRANDED RNA; HEMOGLOBIN; IMMUNOGLOBULIN; INTERLEUKIN 6; KIFUNENSINE; OSELTAMIVIR; PEGINTERFERON LAMBDA; STAT1 PROTEIN; TOLL LIKE RECEPTOR 3; TUMOR NECROSIS FACTOR; INTERFERON; POLYINOSINIC POLYCYTIDYLIC ACID; TLR3 PROTEIN, HUMAN;

ADULT RESPIRATORY DISTRESS SYNDROME; ARTICLE; AUTOSOMAL DOMINANT INHERITANCE; BRAIN CELL; BRONCHIOLITIS; BRONCHITIS; CASE REPORT; CHILD; CLINICAL ARTICLE; CLINICAL FEATURE; CYTOMEGALOVIRUS; DISEASE SEVERITY; EXTRACORPOREAL OXYGENATION; FEMALE; FIBROBLAST; GASTROENTERITIS; HEADACHE; HEPATITIS A VIRUS; HERPES SIMPLEX ENCEPHALITIS; HETEROZYGOTE; HOSPITAL ADMISSION; HOSPITALIZATION; HUMAN; HUMAN ALPHAHERPESVIRUS 1; HUMAN PARVOVIRUS B19; HUMAN RESPIRATORY SYNCYTIAL VIRUS; HUMAN TISSUE; IMMUNE RESPONSE; IMMUNOFLUORESCENCE TEST; IMMUNOGLOBULIN DEFICIENCY; INDUCED PLURIPOTENT STEM CELL; INFLUENZA A; INFLUENZA A VIRUS; INFLUENZA A VIRUS (H1N1); INTENSIVE CARE; LUNG EPITHELIUM; MALE; MEASLES VIRUS; MEMORY CELL; MULTIPLE ORGAN FAILURE; MUMPS VIRUS; NEWBORN; NONINVASIVE VENTILATION; PEDIATRIC WARD; PHENOTYPIC VARIATION; PNEUMONIA; POLYCYTHEMIA; PRE B LYMPHOCYTE; PRESCHOOL CHILD; PRIORITY JOURNAL; REHYDRATION; RESPIRATORY SYNCYTIAL VIRUS INFECTION; ROTAVIRUS INFECTION; RUBELLA VIRUS; SCHOOL CHILD; SEPTIC SHOCK; SEROLOGY; SHOCK; SORE THROAT; VARICELLA ZOSTER VIRUS; VIRUS INFECTION; VOMITING; WHOLE EXOME SEQUENCING; ALLELE; DRUG EFFECT; EPITHELIUM CELL; FATALITY; GENETICS; INFANT; INFLUENZA; INHERITANCE; LOSS OF FUNCTION MUTATION; LUNG; METABOLISM; MISSENSE MUTATION; PATHOLOGY; PHYSIOLOGY; PROTEIN TRANSPORT;

ALLELES; CHILD; CHILD, PRESCHOOL; EPITHELIAL CELLS; FATAL OUTCOME; FEMALE; FIBROBLASTS; HETEROZYGOTE; HUMANS; INDUCED PLURIPOTENT STEM CELLS; INFANT; INFANT, NEWBORN; INFLUENZA A VIRUS; INFLUENZA, HUMAN; INHERITANCE PATTERNS; INTERFERONS; LOSS OF FUNCTION MUTATION; LUNG; MALE; MUTATION, MISSENSE; PNEUMONIA; POLY I-C; PROTEIN TRANSPORT; TOLL-LIKE RECEPTOR 3;

EID: 85071616765     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20181621     Document Type: Article

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