Leukocyte-Derived IFN-α/β and Epithelial IFN-λ Constitute a Compartmentalized Mucosal Defense System that Restricts Enteric Virus Infections

PLoS Pathogens

Volumn 11, Issue 4, 2015, Pages

  Mahlakõiv, Tanel ^a,b   Hernandez, Pedro ^a,c,d   Gronke, Konrad ^a,c,d   Diefenbach, Andreas ^a,d   Staeheli, Peter ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

^b UNIVERSITY OF FREIBURG   (Germany)

^c International Max Planck Research School for Molecular and Cellular Biology   (Germany)

^d UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA BETA INTERFERON RECEPTOR; ALPHA INTERFERON; BETA INTERFERON; GAMMA INTERFERON; GAMMA INTERFERON RECEPTOR; MONOCLONAL ANTIBODY; UVOMORULIN;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DEFENSE MECHANISM; DENDRITIC CELL; ENTERIC VIRUS; FLOW CYTOMETRY; FLUORESCENCE ACTIVATED CELL SORTING; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; INTESTINE EPITHELIUM CELL; LAMINA PROPRIA; LEUKOCYTE; MAMMALIAN ORTHOREOVIRUS; MOUSE; NEWBORN; NONHUMAN; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; TISSUE HOMOGENATE; VIRAL CLEARANCE; VIRUS INFECTION; VIRUS REPLICATION; ANIMAL; CELL SEPARATION; EPITHELIUM CELL; HUMAN; IMMUNOLOGY; INTESTINE MUCOSA; KNOCKOUT MOUSE; MAMMALIAN ORTHOREOVIRUS 3; POLYMERASE CHAIN REACTION; REOVIRUS INFECTION;

MAMMALIAN ORTHOREOVIRUS 3; MUS; ORTHOREOVIRUS;

ANIMALS; CELL SEPARATION; EPITHELIAL CELLS; FLOW CYTOMETRY; HUMANS; IMMUNOHISTOCHEMISTRY; INTERFERON-ALPHA; INTERFERON-BETA; INTERFERON-GAMMA; INTESTINAL MUCOSA; LEUKOCYTES; MAMMALIAN ORTHOREOVIRUS 3; MICE; MICE, KNOCKOUT; POLYMERASE CHAIN REACTION; REOVIRIDAE INFECTIONS;

EID: 84929493527     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1004782     Document Type: Article

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