-
1
-
-
77949902065
-
Autosomal dominant and sporadic mono-cytopenia with susceptibility to mycobacteria, fungi, papillomaviruses, and myelodysplasia
-
Vinh DC, Patel SY, Uzel G, et al. Autosomal dominant and sporadic mono-cytopenia with susceptibility to mycobacteria, fungi, papillomaviruses, and myelodysplasia. Blood 2010; 115:1519-1529.
-
(2010)
Blood
, vol.115
, pp. 1519-1529
-
-
Vinh, D.C.1
Patel, S.Y.2
Uzel, G.3
-
2
-
-
79961046334
-
Dendritic cell, monocyte, B and NK lymphoid deficiency defines the lost lineages of a new GATA-2 dependent myelodysplastic syndrome
-
Bigley V, Collin M. Dendritic cell, monocyte, B and NK lymphoid deficiency defines the lost lineages of a new GATA-2 dependent myelodysplastic syndrome. Haematologica 2011; 96:1081-1083.
-
(2011)
Haematologica
, vol.96
, pp. 1081-1083
-
-
Bigley, V.1
Collin, M.2
-
3
-
-
79961074298
-
Mutations in GATA2 are associated with the autosomal dominant and sporadic monocytopenia and mycobacterial infection (MonoMAC) syndrome
-
Hsu AP, Sampaio EP, Khan J, et al. Mutations in GATA2 are associated with the autosomal dominant and sporadic monocytopenia and mycobacterial infection (MonoMAC) syndrome. Blood 2011; 118:2653-2655.
-
(2011)
Blood
, vol.118
, pp. 2653-2655
-
-
Hsu, A.P.1
Sampaio, E.P.2
Khan, J.3
-
4
-
-
80052089944
-
Exome sequencing identifies GATA-2 mutation as the cause of dendritic cell, monocyte, B and NK lymphoid deficiency
-
Dickinson RE, Griffin H, Bigley V, et al. Exome sequencing identifies GATA-2 mutation as the cause of dendritic cell, monocyte, B and NK lymphoid deficiency. Blood 2011; 118:2656-2658.
-
(2011)
Blood
, vol.118
, pp. 2656-2658
-
-
Dickinson, R.E.1
Griffin, H.2
Bigley, V.3
-
5
-
-
80053383273
-
Heritable GATA2 mutations associated with familial myelodysplastic syndrome and acute myeloid leukemia
-
Hahn CN, Chong CE, Carmichael CL, et al. Heritable GATA2 mutations associated with familial myelodysplastic syndrome and acute myeloid leukemia. Nat Genet 2011; 43:1012-1017.
-
(2011)
Nat Genet
, vol.43
, pp. 1012-1017
-
-
Hahn, C.N.1
Chong, C.E.2
Carmichael, C.L.3
-
6
-
-
80053385569
-
Mutations in GATA2 cause primary lymphedema associated with a predisposition to acute myeloid leukemia (Emberger syndrome)
-
Ostergaard P, Simpson MA, Connell FC, et al. Mutations in GATA2 cause primary lymphedema associated with a predisposition to acute myeloid leukemia (Emberger syndrome). Nat Genet 2011; 43:929-931.
-
(2011)
Nat Genet
, vol.43
, pp. 929-931
-
-
Ostergaard, P.1
Simpson, M.A.2
Connell, F.C.3
-
7
-
-
84894034716
-
GATA2 deficiency: Flesh and blood
-
Horwitz MS. GATA2 deficiency: flesh and blood. Blood 2014; 123:799-800.
-
(2014)
Blood
, vol.123
, pp. 799-800
-
-
Horwitz, M.S.1
-
8
-
-
84896274551
-
Familial myelodysplastic syndrome/acute leukemia syndromes: A review and utility for translational investigations
-
West AH, Godley LA, Churpek JE. Familial myelodysplastic syndrome/acute leukemia syndromes: a review and utility for translational investigations. Ann NY Acad Sci 2014; 1310:111-118.
-
(2014)
Ann NY Acad Sci
, vol.1310
, pp. 111-118
-
-
West, A.H.1
Godley, L.A.2
Churpek, J.E.3
-
9
-
-
84873530537
-
High frequency of GATA2 mutations in patients with mild chronic neutropenia evolving to MonoMacsyndrome, myelodysplasia, and acute myeloid leukemia
-
Pasquet M, Bellanné-Chantelot C, Tavitian S, et al. High frequency of GATA2 mutations in patients with mild chronic neutropenia evolving to MonoMacsyndrome, myelodysplasia, and acute myeloid leukemia. Blood 2013; 121:822-829.
-
(2013)
Blood
, vol.121
, pp. 822-829
-
-
Pasquet, M.1
Bellanné-Chantelot, C.2
Tavitian, S.3
-
10
-
-
34347268119
-
Context-dependent GATA factor function: Combinatorial requirements for transcriptional control in hemato-poietic and endothelial cells
-
Wozniak RJ, Boyer ME, Grass JA, et al. Context-dependent GATA factor function: combinatorial requirements for transcriptional control in hemato-poietic and endothelial cells. J Biol Chem 2007; 282:14665-14674.
-
(2007)
J Biol Chem
, vol.282
, pp. 14665-14674
-
-
Wozniak, R.J.1
Boyer, M.E.2
Grass, J.A.3
-
11
-
-
84867163662
-
Cis-element mutated in GATA2-depen-dent immunodeficiency governs hematopoiesis and vascular integrity
-
Johnson KD, Hsu AP, Ryu MJ, et al. Cis-element mutated in GATA2-depen-dent immunodeficiency governs hematopoiesis and vascular integrity. J Clin Invest 2012; 122:3692-3704.
-
(2012)
J Clin Invest
, vol.122
, pp. 3692-3704
-
-
Johnson, K.D.1
Hsu, A.P.2
Ryu, M.J.3
-
12
-
-
84867163397
-
Conditional Gata2 inactivation results in HSC loss and lymphatic mispatterning
-
Lim KC, Hosoya T, Brandt W, et al. Conditional Gata2 inactivation results in HSC loss and lymphatic mispatterning. J Clin Invest 2012; 122:3705-3717.
-
(2012)
J Clin Invest
, vol.122
, pp. 3705-3717
-
-
Lim, K.C.1
Hosoya, T.2
Brandt, W.3
-
13
-
-
84880449489
-
GATA2 haploinsufficiency caused by mutations in a conserved intronic element leads to MonoMAC syndrome
-
Hsu AP, Johnson KD, Falcone EL, et al. GATA2 haploinsufficiency caused by mutations in a conserved intronic element leads to MonoMAC syndrome. Blood 2013; 121:3830.S1-3837.S7.
-
(2013)
Blood
, vol.121
, pp. 3830S1-3837S7
-
-
Hsu, A.P.1
Johnson, K.D.2
Falcone, E.L.3
-
14
-
-
84894095710
-
GATA2 deficiency: A protean disorder of hematopoiesis, lymphatics, and immunity
-
Spinner MA, Sanchez LA, Hsu AP, et al. GATA2 deficiency: a protean disorder of hematopoiesis, lymphatics, and immunity. Blood 2014; 123:809-821.
-
(2014)
Blood
, vol.123
, pp. 809-821
-
-
Spinner, M.A.1
Sanchez, L.A.2
Hsu, A.P.3
-
15
-
-
0036177862
-
Transcription factor haploinsufficiency: When half a loaf is not enough
-
Seidman JG, Seidman C. Transcription factor haploinsufficiency: when half a loaf is not enough. J Clin Invest 2002; 109:451-455.
-
(2002)
J Clin Invest
, vol.109
, pp. 451-455
-
-
Seidman, J.G.1
Seidman, C.2
-
17
-
-
79952615834
-
5'UTR variants of ribosomal protein S19 transcript determine translational efficiency: Implications for Diamond-Blackfan anemia and tissue variability
-
Badhai J, Schuster J, Gidlöf O, Dahl N. 5'UTR variants of ribosomal protein S19 transcript determine translational efficiency: implications for Diamond-Blackfan anemia and tissue variability. PLoS One 2011; 6:e17672.
-
(2011)
PLoS One
, vol.6
, pp. e17672
-
-
Badhai, J.1
Schuster, J.2
Gidlöf, O.3
Dahl, N.4
-
20
-
-
84887317191
-
Highly variable clinical manifestations in a large family with a novel GATA2 mutation
-
Mutsaers PG, van de Loosdrecht AA, Tawana K, et al. Highly variable clinical manifestations in a large family with a novel GATA2 mutation. Leukemia 2013; 27:2247-2248.
-
(2013)
Leukemia
, vol.27
, pp. 2247-2248
-
-
Mutsaers, P.G.1
Van De Loosdrecht, A.A.2
Tawana, K.3
-
21
-
-
84894078016
-
The evolution of cellular deficiency in GATA2 mutation
-
Dickinson RE, Milne P, Jardine L, et al. The evolution of cellular deficiency in GATA2 mutation. Blood 2014; 123:863-874.
-
(2014)
Blood
, vol.123
, pp. 863-874
-
-
Dickinson, R.E.1
Milne, P.2
Jardine, L.3
-
22
-
-
0029856349
-
Flt3 ligand level reflects hematopoietic progenitor cell function in aplastic anemia and chemotherapy-induced bone marrow aplasia
-
Wodnar-Filipowicz A, Lyman SD, Gratwohl A, et al. Flt3 ligand level reflects hematopoietic progenitor cell function in aplastic anemia and chemotherapy-induced bone marrow aplasia. Blood 1996; 88:4493-4499.
-
(1996)
Blood
, vol.88
, pp. 4493-4499
-
-
Wodnar-Filipowicz, A.1
Lyman, S.D.2
Gratwohl, A.3
-
23
-
-
84874711190
-
Correlation of plasma FL expression with bone marrow irradiation dose
-
Sproull M, Avondoglio D, Kramp T, et al. Correlation of plasma FL expression with bone marrow irradiation dose. PLoS One 2013; 8:e58558.
-
(2013)
PLoS One
, vol.8
, pp. e58558
-
-
Sproull, M.1
Avondoglio, D.2
Kramp, T.3
-
24
-
-
84920876188
-
Bone marrow morphologic and flow cytometric features assist in differentiating GATA2 mutation associated-hypocellular MDS from aplastic anemia
-
Ganapathi KA, Townsley DM, Hsu AP, et al. Bone marrow morphologic and flow cytometric features assist in differentiating GATA2 mutation associated-hypocellular MDS from aplastic anemia. Modern Pathol 2014; 27:332-390.
-
(2014)
Modern Pathol
, vol.27
, pp. 332-390
-
-
Ganapathi, K.A.1
Townsley, D.M.2
Hsu, A.P.3
-
25
-
-
0028022916
-
An early haematopoietic defect in mice lacking the transcription factor GATA-2
-
Tsai FY, Keller G, Kuo FC, et al. An early haematopoietic defect in mice lacking the transcription factor GATA-2. Nature 1994; 371:221-226.
-
(1994)
Nature
, vol.371
, pp. 221-226
-
-
Tsai, F.Y.1
Keller, G.2
Kuo, F.C.3
-
26
-
-
84890847135
-
Gata2 is required for HSC generation and survival
-
de Pater E, Kaimakis P, Vink CS, et al. Gata2 is required for HSC generation and survival. J Exp Med 2013; 210:2843-2850.
-
(2013)
J Exp Med
, vol.210
, pp. 2843-2850
-
-
De Pater, E.1
Kaimakis, P.2
Vink, C.S.3
-
27
-
-
5444223724
-
GATA-2 plays two functionally distinct roles during the ontogeny of hematopoietic stem cells
-
Ling KW, Ottersbach K, van Hamburg JP, et al. GATA-2 plays two functionally distinct roles during the ontogeny of hematopoietic stem cells. J Exp Med 2004; 200:871-882.
-
(2004)
J Exp Med
, vol.200
, pp. 871-882
-
-
Ling, K.W.1
Ottersbach, K.2
Van Hamburg, J.P.3
-
28
-
-
22144476881
-
Haploinsufficiency of GATA-2 perturbs adult hematopoietic stem-cell homeostasis
-
Rodrigues NP, Janzen V, Forkert R, et al. Haploinsufficiency of GATA-2 perturbs adult hematopoietic stem-cell homeostasis. Blood 2005; 106:477-484.
-
(2005)
Blood
, vol.106
, pp. 477-484
-
-
Rodrigues, N.P.1
Janzen, V.2
Forkert, R.3
-
29
-
-
58149399353
-
GATA-2 regulates granulocyte macrophage progenitor cell function
-
Rodrigues NP, Boyd AS, Fugazza C, et al. GATA-2 regulates granulocyte macrophage progenitor cell function. Blood 2008; 112:4862-4873.
-
(2008)
Blood
, vol.112
, pp. 4862-4873
-
-
Rodrigues, N.P.1
Boyd, A.S.2
Fugazza, C.3
-
30
-
-
84863649033
-
Master regulatory GATA transcription factors: Mechanistic principles and emerging links to hematologic malignancies
-
Bresnick EH, Katsumura KR, Lee HY, et al. Master regulatory GATA transcription factors: mechanistic principles and emerging links to hematologic malignancies. Nucleic Acids Res 2012; 40:5819-5831.
-
(2012)
Nucleic Acids Res
, vol.40
, pp. 5819-5831
-
-
Bresnick, E.H.1
Katsumura, K.R.2
Lee, H.Y.3
-
31
-
-
84858673741
-
The role of the GATA2 transcription factor in normal and malignant hematopoiesis
-
Vicente C, Conchillo A, Garćia-Sánchez MA, et al. The role of the GATA2 transcription factor in normal and malignant hematopoiesis. Crit Rev Oncol Hematol 2012; 82:1-17.
-
(2012)
Crit Rev Oncol Hematol
, vol.82
, pp. 1-17
-
-
Vicente, C.1
Conchillo, A.2
Garćia-Sánchez, M.A.3
-
32
-
-
77957348625
-
Combinatorial transcriptional control in blood stem/progenitor cells: Genome-wide analysis of ten major transcrip-tional regulators
-
Wilson NK, Foster SD, Wang X, et al. Combinatorial transcriptional control in blood stem/progenitor cells: genome-wide analysis of ten major transcrip-tional regulators. Cell Stem Cell 2010; 7:532-544.
-
(2010)
Cell Stem Cell
, vol.7
, pp. 532-544
-
-
Wilson, N.K.1
Foster, S.D.2
Wang, X.3
-
33
-
-
84887650018
-
Genome-wide analysis of transcriptional regulators in human HSPCs reveals a densely interconnected network of coding and noncoding genes
-
Beck D, Thoms JA, Perera D, et al. Genome-wide analysis of transcriptional regulators in human HSPCs reveals a densely interconnected network of coding and noncoding genes. Blood 2013; 122:e12-22.
-
(2013)
Blood
, vol.122
, pp. e12-22
-
-
Beck, D.1
Thoms, J.A.2
Perera, D.3
-
34
-
-
78751523598
-
MicroRNA-146a disrupts hematopoietic differentiation and survival
-
e4
-
Starczynowski DT, Kuchenbauer F, Wegrzyn J, et al. MicroRNA-146a disrupts hematopoietic differentiation and survival. Exp Hematol 2011; 39:167-178; e4.
-
(2011)
Exp Hematol
, vol.39
, pp. 167-178
-
-
Starczynowski, D.T.1
Kuchenbauer, F.2
Wegrzyn, J.3
-
35
-
-
84875786889
-
The Yin and Yang of microRNAs: Leukemia and immunity
-
So AY, Zhao JL, Baltimore D. The Yin and Yang of microRNAs: leukemia and immunity. Immunol Rev 2013; 253:129-145.
-
(2013)
Immunol Rev
, vol.253
, pp. 129-145
-
-
So, A.Y.1
Zhao, J.L.2
Baltimore, D.3
-
36
-
-
79959362128
-
NF-kappaB dysregulation in microRNA-146a-deficient mice drives the development of myeloid malignancies
-
Zhao JL, Rao DS, Boldin MP, et al. NF-kappaB dysregulation in microRNA-146a-deficient mice drives the development of myeloid malignancies. Proc Natl Acad Sci USA 2011; 108:9184-9189.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 9184-9189
-
-
Zhao, J.L.1
Rao, D.S.2
Boldin, M.P.3
-
37
-
-
84863012056
-
Loss-of-function germline GATA2 mutations in patients with MDS/AML or MonoMAC syndrome and primary lymphedema reveal a key role for GATA2 in the lymphatic vasculature
-
Kazenwadel J, Secker GA, Liu YJ, et al. Loss-of-function germline GATA2 mutations in patients with MDS/AML or MonoMAC syndrome and primary lymphedema reveal a key role for GATA2 in the lymphatic vasculature. Blood 2012; 119:1283-1291.
-
(2012)
Blood
, vol.119
, pp. 1283-1291
-
-
Kazenwadel, J.1
Secker, G.A.2
Liu, Y.J.3
-
38
-
-
79961058537
-
Myelodysplasia in autosomal dominant and sporadic monocytopenia immunodeficiency syndrome: Diagnostic features and clinical implications
-
Calvo KR, Vinh DC, Maric I, et al. Myelodysplasia in autosomal dominant and sporadic monocytopenia immunodeficiency syndrome: diagnostic features and clinical implications. Haematologica 2011; 96:1221-1225.
-
(2011)
Haematologica
, vol.96
, pp. 1221-1225
-
-
Calvo, K.R.1
Vinh, D.C.2
Maric, I.3
-
40
-
-
84896732313
-
Acquired ASXL1 mutations are common in patients with inherited GATA2 mutations and correlate with myeloid transformation
-
West RR, Hsu AP, Holland SM, et al. Acquired ASXL1 mutations are common in patients with inherited GATA2 mutations and correlate with myeloid transformation. Haematologica 2014; 99:276-281.
-
(2014)
Haematologica
, vol.99
, pp. 276-281
-
-
West, R.R.1
Hsu, A.P.2
Holland, S.M.3
-
41
-
-
79959317767
-
Prognostic significance of ASXL1 mutations in patients with myelodysplastic syndromes
-
Thol F, Friesen I, Damm F, et al. Prognostic significance of ASXL1 mutations in patients with myelodysplastic syndromes. J Clin Oncol 2011; 29:2499-2506.
-
(2011)
J Clin Oncol
, vol.29
, pp. 2499-2506
-
-
Thol, F.1
Friesen, I.2
Damm, F.3
-
42
-
-
84862129223
-
Germ-line GATA2 p.THR354MET mutation in familial myelodysplastic syndrome with acquired monosomy 7 and ASXL1 mutation demonstrating rapid onset and poor survival
-
Bödör C, Renneville A, Smith M, et al. Germ-line GATA2 p.THR354MET mutation in familial myelodysplastic syndrome with acquired monosomy 7 and ASXL1 mutation demonstrating rapid onset and poor survival. Haematologica 2012; 97:890-894.
-
(2012)
Haematologica
, vol.97
, pp. 890-894
-
-
Bödör, C.1
Renneville, A.2
Smith, M.3
-
43
-
-
84905690478
-
Epigenetic regulation of GATA2 and its impact on normal karyotype acute myeloid leukemia
-
Celton M, Forest A, Gosse G, et al. Epigenetic regulation of GATA2 and its impact on normal karyotype acute myeloid leukemia. Leukemia 2014; 28:1617-1626.
-
(2014)
Leukemia
, vol.28
, pp. 1617-1626
-
-
Celton, M.1
Forest, A.2
Gosse, G.3
-
44
-
-
84889588564
-
Mutations of the GATA2 and CEBPA genes in paediatric acute myeloid leukaemia
-
Shiba N, Funato M, Ohki K, et al. Mutations of the GATA2 and CEBPA genes in paediatric acute myeloid leukaemia. Br J Haematol 2014; 164:142-145.
-
(2014)
Br J Haematol
, vol.164
, pp. 142-145
-
-
Shiba, N.1
Funato, M.2
Ohki, K.3
-
45
-
-
84898494315
-
A single oncogenic enhancer rearrangement causes concomitant EVI1 and GATA2 deregulation in leukemia
-
Gröschel S, Sanders MA, Hoogenboezem R, et al. A single oncogenic enhancer rearrangement causes concomitant EVI1 and GATA2 deregulation in leukemia. Cell 2014; 157:369-381.
-
(2014)
Cell
, vol.157
, pp. 369-381
-
-
Gröschel, S.1
Sanders, M.A.2
Hoogenboezem, R.3
-
46
-
-
84898420078
-
A remote GATA2 hematopoietic enhancer drives leukemogenesis in inv(3)(q21;q26) by activating EVI1 expression
-
Yamazaki H, Suzuki M, Otsuki A, et al. A remote GATA2 hematopoietic enhancer drives leukemogenesis in inv(3)(q21;q26) by activating EVI1 expression. Cancer Cell 2014; 25:415-427.
-
(2014)
Cancer Cell
, vol.25
, pp. 415-427
-
-
Yamazaki, H.1
Suzuki, M.2
Otsuki, A.3
-
47
-
-
80053342603
-
Successful allogeneic hematopoietic stem cell transplantation for GATA2 deficiency
-
Cuellar-Rodriguez J, Gea-Banacloche J, Freeman AF, et al. Successful allogeneic hematopoietic stem cell transplantation for GATA2 deficiency. Blood 2011; 118:3715-3720.
-
(2011)
Blood
, vol.118
, pp. 3715-3720
-
-
Cuellar-Rodriguez, J.1
Gea-Banacloche, J.2
Freeman, A.F.3
-
48
-
-
84912570787
-
Reduced intensity allogeneic hematopoietic stem-cell transplantation for GATA2 deficiency
-
[Epub ahead of print]
-
Grossman J, Cuellar-Rodriguez J, Geo-Banacloche J, et al. Reduced intensity allogeneic hematopoietic stem-cell transplantation for GATA2 deficiency. Biol Blood Marrow Transplant 2014. [Epub ahead of print]
-
(2014)
Biol Blood Marrow Transplant
-
-
Grossman, J.1
Cuellar-Rodriguez, J.2
Geo-Banacloche, J.3
|