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Volumn 145, Issue 8, 2019, Pages 2021-2031

Fecal microbiota transplantation in cancer management: Current status and perspectives

Author keywords

cancer; dysbiosis; fecal microbiota transplantation; gut microbiota; therapy

Indexed keywords

BILE ACID METABOLISM; BREAST CANCER; CANCER GROWTH; CANCER IMMUNOTHERAPY; CANCER THERAPY; CLINICAL EFFECTIVENESS; CLOSTRIDIUM DIFFICILE INFECTION; DYSBIOSIS; FECAL MICROBIOTA TRANSPLANTATION; GRAFT VERSUS HOST REACTION; HUMAN; INTESTINE FLORA; LIVER CELL CARCINOMA; MALIGNANT NEOPLASM; MELANOMA; NONHUMAN; PANCREAS CANCER; PATIENT SAFETY; PRIORITY JOURNAL; RADIATION ENTEROPATHY; REVIEW; TREATMENT OUTCOME; CLOSTRIDIOIDES DIFFICILE; CLOSTRIDIUM INFECTION; FECES; MICROBIOLOGY; MICROFLORA; NEOPLASM; PATHOPHYSIOLOGY; PHYSIOLOGY; PROCEDURES;

EID: 85059255050     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.32003     Document Type: Review
Times cited : (211)

References (139)
  • 1
    • 84961288867 scopus 로고    scopus 로고
    • Are we really vastly outnumbered? Revisiting the ratio of bacterial to host cells in humans
    • Sender R, Fuchs S, Milo R. Are we really vastly outnumbered? Revisiting the ratio of bacterial to host cells in humans. Cell 2016;164:337–40.
    • (2016) Cell , vol.164 , pp. 337-340
    • Sender, R.1    Fuchs, S.2    Milo, R.3
  • 2
    • 84866146940 scopus 로고    scopus 로고
    • Diversity, stability and resilience of the human gut microbiota
    • Lozupone CA, Stombaugh JI, Gordon JI, et al. Diversity, stability and resilience of the human gut microbiota. Nature 2012;489:220–30.
    • (2012) Nature , vol.489 , pp. 220-230
    • Lozupone, C.A.1    Stombaugh, J.I.2    Gordon, J.I.3
  • 3
    • 84904512621 scopus 로고    scopus 로고
    • Activation of epidermal growth factor receptor mediates mucin production stimulated by p40, a lactobacillus rhamnosus GG-derived protein
    • Wang L, Cao H, Liu L, et al. Activation of epidermal growth factor receptor mediates mucin production stimulated by p40, a lactobacillus rhamnosus GG-derived protein. J Biol Chem 2014;289:20234–44.
    • (2014) J Biol Chem , vol.289 , pp. 20234-20244
    • Wang, L.1    Cao, H.2    Liu, L.3
  • 4
    • 84971201113 scopus 로고    scopus 로고
    • Gut microbiota, metabolites and host immunity
    • Rooks MG, Garrett WS. Gut microbiota, metabolites and host immunity. Nat Rev Immunol 2016;16:341–52.
    • (2016) Nat Rev Immunol , vol.16 , pp. 341-352
    • Rooks, M.G.1    Garrett, W.S.2
  • 5
    • 85028766330 scopus 로고    scopus 로고
    • Dysbiosis contributes to chronic constipation development via regulation of serotonin transporter in the intestine
    • Cao H, Liu X, An Y, et al. Dysbiosis contributes to chronic constipation development via regulation of serotonin transporter in the intestine. Sci Rep 2017;7:10322.
    • (2017) Sci Rep , vol.7 , pp. 10322
    • Cao, H.1    Liu, X.2    An, Y.3
  • 6
    • 84990234576 scopus 로고    scopus 로고
    • Signals from the gut microbiota to distant organs in physiology and disease
    • Schroeder BO, Bäckhed F. Signals from the gut microbiota to distant organs in physiology and disease. Nat Med 2016;22:1079–89.
    • (2016) Nat Med , vol.22 , pp. 1079-1089
    • Schroeder, B.O.1    Bäckhed, F.2
  • 7
    • 85019666712 scopus 로고    scopus 로고
    • The microbiome and hepatobiliary-pancreatic cancers
    • Mima K, Nakagawa S, Sawayama H, et al. The microbiome and hepatobiliary-pancreatic cancers. Cancer Lett 2017;402:9–15.
    • (2017) Cancer Lett , vol.402 , pp. 9-15
    • Mima, K.1    Nakagawa, S.2    Sawayama, H.3
  • 8
    • 85005965070 scopus 로고    scopus 로고
    • The human intestinal microbiome in health and disease
    • Lynch SV, Pedersen O. The human intestinal microbiome in health and disease. N Engl J Med 2016;375:2369–79.
    • (2016) N Engl J Med , vol.375 , pp. 2369-2379
    • Lynch, S.V.1    Pedersen, O.2
  • 9
    • 84867192879 scopus 로고    scopus 로고
    • Intestinal inflammation targets cancer-inducing activity of the microbiota
    • Arthur JC, Perez-Chanona E, Mühlbauer M, et al. Intestinal inflammation targets cancer-inducing activity of the microbiota. Science 2012;338:120–3.
    • (2012) Science , vol.338 , pp. 120-123
    • Arthur, J.C.1    Perez-Chanona, E.2    Mühlbauer, M.3
  • 10
    • 84983143348 scopus 로고    scopus 로고
    • Potential role of Escherichia coli DNA mismatch repair proteins in colon cancer
    • Khan S. Potential role of Escherichia coli DNA mismatch repair proteins in colon cancer. Crit Rev Oncol Hematol 2015;96:475–82.
    • (2015) Crit Rev Oncol Hematol , vol.96 , pp. 475-482
    • Khan, S.1
  • 11
    • 85019078234 scopus 로고    scopus 로고
    • Prediction of mycoplasma hominis proteins targeting in mitochondria and cytoplasm of host cells and their implication in prostate cancer etiology
    • Khan S, Zakariah M, Rolfo C, et al. Prediction of mycoplasma hominis proteins targeting in mitochondria and cytoplasm of host cells and their implication in prostate cancer etiology. Oncotarget 2017;8:30830–43.
    • (2017) Oncotarget , vol.8 , pp. 30830-30843
    • Khan, S.1    Zakariah, M.2    Rolfo, C.3
  • 12
    • 84957965195 scopus 로고    scopus 로고
    • Computational prediction of mycoplasma hominis proteins targeting in nucleus of host cell and their implication in prostate cancer etiology
    • Khan S, Zakariah M, Palaniappan S. Computational prediction of mycoplasma hominis proteins targeting in nucleus of host cell and their implication in prostate cancer etiology. Tumour Biol 2016;37:10805–13.
    • (2016) Tumour Biol , vol.37 , pp. 10805-10813
    • Khan, S.1    Zakariah, M.2    Palaniappan, S.3
  • 13
    • 84960502575 scopus 로고    scopus 로고
    • Systems biology approaches for the prediction of possible role of chlamydia pneumoniae proteins in the etiology of lung cancer
    • Khan S, Imran A, Khan AA, et al. Systems biology approaches for the prediction of possible role of chlamydia pneumoniae proteins in the etiology of lung cancer. PLoS One 2016;11:e0148530.
    • (2016) PLoS One , vol.11
    • Khan, S.1    Imran, A.2    Khan, A.A.3
  • 14
    • 84873019302 scopus 로고    scopus 로고
    • Duodenal infusion of donor feces for recurrent Clostridium difficile
    • van Nood E, Vrieze A, Nieuwdorp M, et al. Duodenal infusion of donor feces for recurrent Clostridium difficile. N Engl J Med 2013;368:407–15.
    • (2013) N Engl J Med , vol.368 , pp. 407-415
    • van Nood, E.1    Vrieze, A.2    Nieuwdorp, M.3
  • 15
    • 82955233474 scopus 로고    scopus 로고
    • Treating Clostridium difficile infection with fecal microbiota transplantation
    • Bakken JS, Borody T, Brandt LJ, et al. Treating Clostridium difficile infection with fecal microbiota transplantation. Clin Gastroenterol Hepatol 2011;9:1044–9.
    • (2011) Clin Gastroenterol Hepatol , vol.9 , pp. 1044-1049
    • Bakken, J.S.1    Borody, T.2    Brandt, L.J.3
  • 16
    • 84869395353 scopus 로고    scopus 로고
    • Should we standardize the 1,700-year-old fecal microbiota transplantation
    • Zhang F, Luo W, Shi Y, et al. Should we standardize the 1,700-year-old fecal microbiota transplantation. Am J Gastroenterol 2012;107:1755–6.
    • (2012) Am J Gastroenterol , vol.107 , pp. 1755-1756
    • Zhang, F.1    Luo, W.2    Shi, Y.3
  • 17
    • 0001412472 scopus 로고
    • Fecal enema as an adjunct in the treatment of pseudomembranous enterocolitis
    • Eiseman B, Silen W, Bascom GS, et al. Fecal enema as an adjunct in the treatment of pseudomembranous enterocolitis. Surgery 1958;44:854–9.
    • (1958) Surgery , vol.44 , pp. 854-859
    • Eiseman, B.1    Silen, W.2    Bascom, G.S.3
  • 18
    • 0021097993 scopus 로고
    • Relapsing clostridium difficile enterocolitis cured by rectal infusion of homologous faeces
    • Schwan A, Sjölin S, Trottestam U, et al. Relapsing clostridium difficile enterocolitis cured by rectal infusion of homologous faeces. Lancet 1983;2:845.
    • (1983) Lancet , vol.2 , pp. 845
    • Schwan, A.1    Sjölin, S.2    Trottestam, U.3
  • 19
    • 84875952150 scopus 로고    scopus 로고
    • Guidelines for diagnosis, treatment, and prevention of Clostridium difficile infections
    • quiz 499
    • Surawicz CM, Brandt LJ, Binion DG, et al. Guidelines for diagnosis, treatment, and prevention of Clostridium difficile infections. Am J Gastroenterol 2013;108:478–98. quiz 499.
    • (2013) Am J Gastroenterol , vol.108 , pp. 478-498
    • Surawicz, C.M.1    Brandt, L.J.2    Binion, D.G.3
  • 20
    • 84940750563 scopus 로고    scopus 로고
    • Emerging role of fecal microbiota therapy in the treatment of gastrointestinal and extra-gastrointestinal diseases
    • Konturek PC, Haziri D, Brzozowski T, et al. Emerging role of fecal microbiota therapy in the treatment of gastrointestinal and extra-gastrointestinal diseases. J Physiol Pharmacol 2015;66:483–91.
    • (2015) J Physiol Pharmacol , vol.66 , pp. 483-491
    • Konturek, P.C.1    Haziri, D.2    Brzozowski, T.3
  • 21
    • 84920931626 scopus 로고    scopus 로고
    • Fecal microbiota transplantation broadening its application beyond intestinal disorders
    • Xu MQ, Cao HL, Wang WQ, et al. Fecal microbiota transplantation broadening its application beyond intestinal disorders. World J Gastroenterol 2015;21:102–11.
    • (2015) World J Gastroenterol , vol.21 , pp. 102-111
    • Xu, M.Q.1    Cao, H.L.2    Wang, W.Q.3
  • 22
    • 85020737567 scopus 로고    scopus 로고
    • Systematic review with meta-analysis: faecal microbiota transplantation for the induction of remission for active ulcerative colitis
    • Costello SP, Soo W, Bryant RV, et al. Systematic review with meta-analysis: faecal microbiota transplantation for the induction of remission for active ulcerative colitis. Aliment Pharmacol Ther 2017;46:213–24.
    • (2017) Aliment Pharmacol Ther , vol.46 , pp. 213-224
    • Costello, S.P.1    Soo, W.2    Bryant, R.V.3
  • 23
    • 85052904982 scopus 로고    scopus 로고
    • The use of faecal microbiota transplant as treatment for recurrent or refractory Clostridium difficile infection and other potential indications: joint British Society of Gastroenterology (BSG) and Healthcare Infection Society (HIS) guidelines
    • Mullish BH, Quraishi MN, Segal JP, et al. The use of faecal microbiota transplant as treatment for recurrent or refractory Clostridium difficile infection and other potential indications: joint British Society of Gastroenterology (BSG) and Healthcare Infection Society (HIS) guidelines. Gut 2018;67:1920–41.
    • (2018) Gut , vol.67 , pp. 1920-1941
    • Mullish, B.H.1    Quraishi, M.N.2    Segal, J.P.3
  • 24
    • 84931295496 scopus 로고    scopus 로고
    • Update on fecal microbiota transplantation 2015: indications, methodologies, mechanisms, and outlook
    • Kelly CR, Kahn S, Kashyap P, et al. Update on fecal microbiota transplantation 2015: indications, methodologies, mechanisms, and outlook. Gastroenterology 2015;149:223–37.
    • (2015) Gastroenterology , vol.149 , pp. 223-237
    • Kelly, C.R.1    Kahn, S.2    Kashyap, P.3
  • 25
    • 84941733300 scopus 로고    scopus 로고
    • Faecal microbiota transplant for recurrent Clostridium difficile infection using long-term frozen stool is effective: clinical efficacy and bacterial viability data
    • Costello SP, Conlon MA, Vuaran MS, et al. Faecal microbiota transplant for recurrent Clostridium difficile infection using long-term frozen stool is effective: clinical efficacy and bacterial viability data. Aliment Pharmacol Ther 2015;42:1011–8.
    • (2015) Aliment Pharmacol Ther , vol.42 , pp. 1011-1018
    • Costello, S.P.1    Conlon, M.A.2    Vuaran, M.S.3
  • 26
    • 84919624382 scopus 로고    scopus 로고
    • Fecal microbiota transplantation through mid-gut for refractory Crohn's disease: safety, feasibility, and efficacy trial results
    • Cui B, Feng Q, Wang H, et al. Fecal microbiota transplantation through mid-gut for refractory Crohn's disease: safety, feasibility, and efficacy trial results. J Gastroenterol Hepatol 2015;30:51–8.
    • (2015) J Gastroenterol Hepatol , vol.30 , pp. 51-58
    • Cui, B.1    Feng, Q.2    Wang, H.3
  • 27
    • 85013456475 scopus 로고    scopus 로고
    • Randomised clinical trial: faecal microbiota transplantation for recurrent Clostridum difficile infection - fresh, or frozen, or lyophilised microbiota from a small pool of healthy donors delivered by colonoscopy
    • Jiang ZD, Ajami NJ, Petrosino JF, et al. Randomised clinical trial: faecal microbiota transplantation for recurrent Clostridum difficile infection - fresh, or frozen, or lyophilised microbiota from a small pool of healthy donors delivered by colonoscopy. Aliment Pharmacol Ther 2017;45:899–908.
    • (2017) Aliment Pharmacol Ther , vol.45 , pp. 899-908
    • Jiang, Z.D.1    Ajami, N.J.2    Petrosino, J.F.3
  • 28
    • 84905968786 scopus 로고    scopus 로고
    • Fecal microbiota transplantation for the treatment of Clostridium difficile infection: a systematic review
    • Cammarota G, Ianiro G, Gasbarrini A. Fecal microbiota transplantation for the treatment of Clostridium difficile infection: a systematic review. J Clin Gastroenterol 2014;48:693–702.
    • (2014) J Clin Gastroenterol , vol.48 , pp. 693-702
    • Cammarota, G.1    Ianiro, G.2    Gasbarrini, A.3
  • 29
    • 85037042631 scopus 로고    scopus 로고
    • Effect of Oral capsule- vs colonoscopy-delivered fecal microbiota transplantation on recurrent Clostridium difficile infection: a randomized clinical trial
    • Kao D, Roach B, Silva M, et al. Effect of Oral capsule- vs colonoscopy-delivered fecal microbiota transplantation on recurrent Clostridium difficile infection: a randomized clinical trial. JAMA 2017;318:1985–93.
    • (2017) JAMA , vol.318 , pp. 1985-1993
    • Kao, D.1    Roach, B.2    Silva, M.3
  • 30
    • 84959872636 scopus 로고    scopus 로고
    • Gut microbiota role in irritable bowel syndrome: new therapeutic strategies
    • Distrutti E, Monaldi L, Ricci P, et al. Gut microbiota role in irritable bowel syndrome: new therapeutic strategies. World J Gastroenterol 2016;22:2219–41.
    • (2016) World J Gastroenterol , vol.22 , pp. 2219-2241
    • Distrutti, E.1    Monaldi, L.2    Ricci, P.3
  • 31
    • 85011019659 scopus 로고    scopus 로고
    • European consensus conference on faecal microbiota transplantation in clinical practice
    • Cammarota G, Ianiro G, Tilg H, et al. European consensus conference on faecal microbiota transplantation in clinical practice. Gut 2017;66:569–80.
    • (2017) Gut , vol.66 , pp. 569-580
    • Cammarota, G.1    Ianiro, G.2    Tilg, H.3
  • 32
    • 85043316087 scopus 로고    scopus 로고
    • Faecal microbiota transplantation in clinical practice
    • Terveer EM, van Beurden YH, Goorhuis A, et al. Faecal microbiota transplantation in clinical practice. Gut 2018;67:196.
    • (2018) Gut , vol.67 , pp. 196
    • Terveer, E.M.1    van Beurden, Y.H.2    Goorhuis, A.3
  • 33
    • 84923933501 scopus 로고    scopus 로고
    • Cancer and the microbiome: potential applications as new tumor biomarker
    • Shahanavaj K, Gil-Bazo I, Castiglia M, et al. Cancer and the microbiome: potential applications as new tumor biomarker. Expert Rev Anticancer Ther 2015;15:317–30.
    • (2015) Expert Rev Anticancer Ther , vol.15 , pp. 317-330
    • Shahanavaj, K.1    Gil-Bazo, I.2    Castiglia, M.3
  • 34
    • 85028471063 scopus 로고    scopus 로고
    • The gut microbiome and liver cancer: mechanisms and clinical translation
    • Yu LX, Schwabe RF. The gut microbiome and liver cancer: mechanisms and clinical translation. Nat Rev Gastroenterol Hepatol 2017;14:527–39.
    • (2017) Nat Rev Gastroenterol Hepatol , vol.14 , pp. 527-539
    • Yu, L.X.1    Schwabe, R.F.2
  • 35
    • 85028810546 scopus 로고    scopus 로고
    • The gastrointestinal microbiota and its role in oncogenesis
    • Lam SY, Yu J, Wong SH, et al. The gastrointestinal microbiota and its role in oncogenesis. Best Pract Res Clin Gastroenterol 2017;31:607–18.
    • (2017) Best Pract Res Clin Gastroenterol , vol.31 , pp. 607-618
    • Lam, S.Y.1    Yu, J.2    Wong, S.H.3
  • 36
    • 85046048647 scopus 로고    scopus 로고
    • The microbiome in cancer immunotherapy: diagnostic tools and therapeutic strategies
    • Zitvogel L, Ma Y, Raoult D, et al. The microbiome in cancer immunotherapy: diagnostic tools and therapeutic strategies. Science 2018;359:1366–70.
    • (2018) Science , vol.359 , pp. 1366-1370
    • Zitvogel, L.1    Ma, Y.2    Raoult, D.3
  • 37
    • 84924026956 scopus 로고    scopus 로고
    • Potential of fecal microbiota for early-stage detection of colorectal cancer
    • Zeller G, Tap J, Voigt AY, et al. Potential of fecal microbiota for early-stage detection of colorectal cancer. Mol Syst Biol 2014;10:766.
    • (2014) Mol Syst Biol , vol.10 , pp. 766
    • Zeller, G.1    Tap, J.2    Voigt, A.Y.3
  • 38
    • 85048754113 scopus 로고    scopus 로고
    • Mucosal microbiome dysbiosis in gastric carcinogenesis
    • Coker OO, Dai Z, Nie Y, et al. Mucosal microbiome dysbiosis in gastric carcinogenesis. Gut 2018;67:1024–32.
    • (2018) Gut , vol.67 , pp. 1024-1032
    • Coker, O.O.1    Dai, Z.2    Nie, Y.3
  • 39
    • 85035071123 scopus 로고    scopus 로고
    • Gavage of fecal samples from patients with colorectal cancer promotes intestinal carcinogenesis in germ-free and conventional mice
    • e6
    • Wong SH, Zhao L, Zhang X, et al. Gavage of fecal samples from patients with colorectal cancer promotes intestinal carcinogenesis in germ-free and conventional mice. Gastroenterology 2017;153:1621–33.e6.
    • (2017) Gastroenterology , vol.153 , pp. 1621-1633
    • Wong, S.H.1    Zhao, L.2    Zhang, X.3
  • 40
    • 84983490017 scopus 로고    scopus 로고
    • Antibiotics as deep modulators of gut microbiota: between good and evil
    • Ianiro G, Tilg H, Gasbarrini A. Antibiotics as deep modulators of gut microbiota: between good and evil. Gut 2016;65:1906–15.
    • (2016) Gut , vol.65 , pp. 1906-1915
    • Ianiro, G.1    Tilg, H.2    Gasbarrini, A.3
  • 41
    • 84952975031 scopus 로고    scopus 로고
    • Frequent use of antibiotics is associated with colorectal cancer risk: results of a nested case-control study
    • Dik VK, van Oijen MG, Smeets HM, et al. Frequent use of antibiotics is associated with colorectal cancer risk: results of a nested case-control study. Dig Dis Sci 2016;61:255–64.
    • (2016) Dig Dis Sci , vol.61 , pp. 255-264
    • Dik, V.K.1    van Oijen, M.G.2    Smeets, H.M.3
  • 42
    • 84928183077 scopus 로고    scopus 로고
    • Impact of antibiotic exposure on the risk of colorectal cancer
    • Boursi B, Haynes K, Mamtani R, et al. Impact of antibiotic exposure on the risk of colorectal cancer. Pharmacoepidemiol Drug Saf 2015;24:534–42.
    • (2015) Pharmacoepidemiol Drug Saf , vol.24 , pp. 534-542
    • Boursi, B.1    Haynes, K.2    Mamtani, R.3
  • 43
    • 84902291887 scopus 로고    scopus 로고
    • Infection, antibiotic therapy and risk of colorectal cancer: a nationwide nested case-control study in patients with type 2 diabetes mellitus
    • Wang JL, Chang CH, Lin JW, et al. Infection, antibiotic therapy and risk of colorectal cancer: a nationwide nested case-control study in patients with type 2 diabetes mellitus. Int J Cancer 2014;135:956–67.
    • (2014) Int J Cancer , vol.135 , pp. 956-967
    • Wang, J.L.1    Chang, C.H.2    Lin, J.W.3
  • 44
    • 85026767479 scopus 로고    scopus 로고
    • Long-term use of antibiotics and risk of colorectal adenoma
    • Cao Y, Wu K, Mehta R, et al. Long-term use of antibiotics and risk of colorectal adenoma. Gut 2018;67:672–8.
    • (2018) Gut , vol.67 , pp. 672-678
    • Cao, Y.1    Wu, K.2    Mehta, R.3
  • 45
    • 84970965574 scopus 로고    scopus 로고
    • Recurrent antibiotic exposure may promote cancer formation--another step in understanding the role of the human microbiota
    • Boursi B, Mamtani R, Haynes K, et al. Recurrent antibiotic exposure may promote cancer formation--another step in understanding the role of the human microbiota. Eur J Cancer 2015;51:2655–64.
    • (2015) Eur J Cancer , vol.51 , pp. 2655-2664
    • Boursi, B.1    Mamtani, R.2    Haynes, K.3
  • 46
    • 85044952219 scopus 로고    scopus 로고
    • Antibiotic-mediated bacteriome depletion in ApcMin/+ mice is associated with reduction in mucus-producing goblet cells and increased colorectal cancer progression
    • Kaur K, Saxena A, Debnath I, et al. Antibiotic-mediated bacteriome depletion in ApcMin/+ mice is associated with reduction in mucus-producing goblet cells and increased colorectal cancer progression. Cancer Med 2018;7:2003–12.
    • (2018) Cancer Med , vol.7 , pp. 2003-2012
    • Kaur, K.1    Saxena, A.2    Debnath, I.3
  • 47
    • 85034809112 scopus 로고    scopus 로고
    • Analysis of fusobacterium persistence and antibiotic response in colorectal cancer
    • Bullman S, Pedamallu CS, Sicinska E, et al. Analysis of fusobacterium persistence and antibiotic response in colorectal cancer. Science 2017;358:1443–8.
    • (2017) Science , vol.358 , pp. 1443-1448
    • Bullman, S.1    Pedamallu, C.S.2    Sicinska, E.3
  • 48
    • 84930575721 scopus 로고    scopus 로고
    • Metabolism links bacterial biofilms and colon carcinogenesis
    • Johnson CH, Dejea CM, Edler D, et al. Metabolism links bacterial biofilms and colon carcinogenesis. Cell Metab 2015;21:891–7.
    • (2015) Cell Metab , vol.21 , pp. 891-897
    • Johnson, C.H.1    Dejea, C.M.2    Edler, D.3
  • 49
    • 84938917629 scopus 로고    scopus 로고
    • Gut microbiota facilitates dietary heme-induced epithelial hyperproliferation by opening the mucus barrier in colon
    • Ijssennagger N, Belzer C, Hooiveld GJ, et al. Gut microbiota facilitates dietary heme-induced epithelial hyperproliferation by opening the mucus barrier in colon. Proc Natl Acad Sci USA 2015;112:10038–43.
    • (2015) Proc Natl Acad Sci USA , vol.112 , pp. 10038-10043
    • Ijssennagger, N.1    Belzer, C.2    Hooiveld, G.J.3
  • 50
    • 84919643021 scopus 로고    scopus 로고
    • High-fat-diet-mediated dysbiosis promotes intestinal carcinogenesis independently of obesity
    • Schulz MD, Atay C, Heringer J, et al. High-fat-diet-mediated dysbiosis promotes intestinal carcinogenesis independently of obesity. Nature 2014;514:508–12.
    • (2014) Nature , vol.514 , pp. 508-512
    • Schulz, M.D.1    Atay, C.2    Heringer, J.3
  • 51
    • 85049300895 scopus 로고    scopus 로고
    • Gut microbiota promotes tumor growth in mice by modulating immune response
    • e6
    • Sethi V, Kurtom S, Tarique M, et al. Gut microbiota promotes tumor growth in mice by modulating immune response. Gastroenterology 2018;155:33–7.e6.
    • (2018) Gastroenterology , vol.155 , pp. 33-37
    • Sethi, V.1    Kurtom, S.2    Tarique, M.3
  • 52
    • 85014107164 scopus 로고    scopus 로고
    • Secondary bile acid-induced dysbiosis promotes intestinal carcinogenesis
    • Cao H, Xu M, Dong W, et al. Secondary bile acid-induced dysbiosis promotes intestinal carcinogenesis. Int J Cancer 2017;140:2545–56.
    • (2017) Int J Cancer , vol.140 , pp. 2545-2556
    • Cao, H.1    Xu, M.2    Dong, W.3
  • 53
    • 85008319428 scopus 로고    scopus 로고
    • Collateral damage: insights into bacterial mechanisms that predispose host cells to cancer
    • Gagnaire A, Nadel B, Raoult D, et al. Collateral damage: insights into bacterial mechanisms that predispose host cells to cancer. Nat Rev Microbiol 2017;15:109–28.
    • (2017) Nat Rev Microbiol , vol.15 , pp. 109-128
    • Gagnaire, A.1    Nadel, B.2    Raoult, D.3
  • 54
    • 84896721521 scopus 로고    scopus 로고
    • Helicobacter pylori-induced gastric inflammation and gastric cancer
    • Wang F, Meng W, Wang B, et al. Helicobacter pylori-induced gastric inflammation and gastric cancer. Cancer Lett 2014;345:196–202.
    • (2014) Cancer Lett , vol.345 , pp. 196-202
    • Wang, F.1    Meng, W.2    Wang, B.3
  • 55
    • 17344379177 scopus 로고    scopus 로고
    • Translocation of helicobacter pylori CagA into gastric epithelial cells by type IV secretion
    • Odenbreit S, Püls J, Sedlmaier B, et al. Translocation of helicobacter pylori CagA into gastric epithelial cells by type IV secretion. Science 2000;287:1497–500.
    • (2000) Science , vol.287 , pp. 1497-1500
    • Odenbreit, S.1    Püls, J.2    Sedlmaier, B.3
  • 56
    • 84936885269 scopus 로고    scopus 로고
    • Helicobacter pylori virulence factor CagA promotes tumorigenesis of gastric cancer via multiple signaling pathways
    • Yong X, Tang B, Li BS, et al. Helicobacter pylori virulence factor CagA promotes tumorigenesis of gastric cancer via multiple signaling pathways. Cell Commun Signal 2015;13:30.
    • (2015) Cell Commun Signal , vol.13 , pp. 30
    • Yong, X.1    Tang, B.2    Li, B.S.3
  • 57
    • 84977601066 scopus 로고    scopus 로고
    • Relationship between VacA toxin and host cell autophagy in helicobacter pylori infection of the human stomach: A few answers, many questions
    • Ricci V. Relationship between VacA toxin and host cell autophagy in helicobacter pylori infection of the human stomach: A few answers, many questions. Toxins (Basel) 2016;8(7):203.
    • (2016) Toxins (Basel) , vol.8 , Issue.7 , pp. 203
    • Ricci, V.1
  • 58
    • 46249092326 scopus 로고    scopus 로고
    • Involvement of vesicle-associated membrane protein 7 in human gastric epithelial cell vacuolation induced by helicobacter pylori-produced VacA
    • Mashima H, Suzuki J, Hirayama T, et al. Involvement of vesicle-associated membrane protein 7 in human gastric epithelial cell vacuolation induced by helicobacter pylori-produced VacA. Infect Immun 2008;76:2296–303.
    • (2008) Infect Immun , vol.76 , pp. 2296-2303
    • Mashima, H.1    Suzuki, J.2    Hirayama, T.3
  • 59
    • 84924971514 scopus 로고    scopus 로고
    • The Bacteroides fragilis toxin gene is prevalent in the colon mucosa of colorectal cancer patients
    • Boleij A, Hechenbleikner EM, Goodwin AC, et al. The Bacteroides fragilis toxin gene is prevalent in the colon mucosa of colorectal cancer patients. Clin Infect Dis 2015;60:208–15.
    • (2015) Clin Infect Dis , vol.60 , pp. 208-215
    • Boleij, A.1    Hechenbleikner, E.M.2    Goodwin, A.C.3
  • 60
    • 84880667574 scopus 로고    scopus 로고
    • The itinerary of streptococcus gallolyticus infection in patients with colonic malignant disease
    • Boleij A, Tjalsma H. The itinerary of streptococcus gallolyticus infection in patients with colonic malignant disease. Lancet Infect Dis 2013;13:719–24.
    • (2013) Lancet Infect Dis , vol.13 , pp. 719-724
    • Boleij, A.1    Tjalsma, H.2
  • 61
    • 85026884966 scopus 로고    scopus 로고
    • Streptococcus gallolyticus subsp. gallolyticus promotes colorectal tumor development
    • Kumar R, Herold JL, Schady D, et al. Streptococcus gallolyticus subsp. gallolyticus promotes colorectal tumor development. PLoS Pathog 2017;13:e1006440.
    • (2017) PLoS Pathog , vol.13
    • Kumar, R.1    Herold, J.L.2    Schady, D.3
  • 62
    • 84896713690 scopus 로고    scopus 로고
    • Colonization of the human gut by E. coli and colorectal cancer risk
    • Bonnet M, Buc E, Sauvanet P, et al. Colonization of the human gut by E. coli and colorectal cancer risk. Clin Cancer Res 2014;20:859–67.
    • (2014) Clin Cancer Res , vol.20 , pp. 859-867
    • Bonnet, M.1    Buc, E.2    Sauvanet, P.3
  • 63
    • 85014373123 scopus 로고    scopus 로고
    • Fusobacterium nucleatum increases proliferation of colorectal cancer cells and tumor development in mice by activating toll-like receptor 4 signaling to nuclear factor-κB, and up-regulating expression of MicroRNA-21
    • e24
    • Yang Y, Weng W, Peng J, et al. Fusobacterium nucleatum increases proliferation of colorectal cancer cells and tumor development in mice by activating toll-like receptor 4 signaling to nuclear factor-κB, and up-regulating expression of MicroRNA-21. Gastroenterology 2017;152:851–66.e24.
    • (2017) Gastroenterology , vol.152 , pp. 851-866
    • Yang, Y.1    Weng, W.2    Peng, J.3
  • 64
    • 84882334105 scopus 로고    scopus 로고
    • Fusobacterium nucleatum promotes colorectal carcinogenesis by modulating E-cadherin/β-catenin signaling via its FadA adhesin
    • Rubinstein MR, Wang X, Liu W, et al. Fusobacterium nucleatum promotes colorectal carcinogenesis by modulating E-cadherin/β-catenin signaling via its FadA adhesin. Cell Host Microbe 2013;14:195–206.
    • (2013) Cell Host Microbe , vol.14 , pp. 195-206
    • Rubinstein, M.R.1    Wang, X.2    Liu, W.3
  • 65
    • 84991644107 scopus 로고    scopus 로고
    • Fap2 mediates fusobacterium nucleatum colorectal adenocarcinoma enrichment by binding to tumor-expressed gal-GalNAc
    • Abed J, Emgård JE, Zamir G, et al. Fap2 mediates fusobacterium nucleatum colorectal adenocarcinoma enrichment by binding to tumor-expressed gal-GalNAc. Cell Host Microbe 2016;20:215–25.
    • (2016) Cell Host Microbe , vol.20 , pp. 215-225
    • Abed, J.1    Emgård, J.E.2    Zamir, G.3
  • 66
    • 85026371130 scopus 로고    scopus 로고
    • Fusobacterium nucleatum promotes Chemoresistance to colorectal cancer by modulating autophagy
    • e16
    • Yu T, Guo F, Yu Y, et al. Fusobacterium nucleatum promotes Chemoresistance to colorectal cancer by modulating autophagy. Cell 2017;170:548–63.e16.
    • (2017) Cell , vol.170 , pp. 548-563
    • Yu, T.1    Guo, F.2    Yu, Y.3
  • 67
    • 85031322306 scopus 로고    scopus 로고
    • Fecal clostridium symbiosum for noninvasive detection of early and advanced colorectal cancer: test and validation studies
    • Xie YH, Gao QY, Cai GX, et al. Fecal clostridium symbiosum for noninvasive detection of early and advanced colorectal cancer: test and validation studies. EBioMedicine 2017;25:32–40.
    • (2017) EBioMedicine , vol.25 , pp. 32-40
    • Xie, Y.H.1    Gao, Q.Y.2    Cai, G.X.3
  • 68
    • 84994759860 scopus 로고    scopus 로고
    • Quantitation of faecal fusobacterium improves faecal immunochemical test in detecting advanced colorectal neoplasia
    • Wong SH, Tny K, Chow TC, et al. Quantitation of faecal fusobacterium improves faecal immunochemical test in detecting advanced colorectal neoplasia. Gut 2017;66:1441–8.
    • (2017) Gut , vol.66 , pp. 1441-1448
    • Wong, S.H.1    Tny, K.2    Chow, T.C.3
  • 69
    • 84888059687 scopus 로고    scopus 로고
    • The intestinal microbiota modulates the anticancer immune effects of cyclophosphamide
    • Viaud S, Saccheri F, Mignot G, et al. The intestinal microbiota modulates the anticancer immune effects of cyclophosphamide. Science 2013;342:971–6.
    • (2013) Science , vol.342 , pp. 971-976
    • Viaud, S.1    Saccheri, F.2    Mignot, G.3
  • 70
    • 84994831796 scopus 로고    scopus 로고
    • Enterococcus hirae and Barnesiella intestinihominis facilitate cyclophosphamide-induced therapeutic immunomodulatory effects
    • Daillère R, Vétizou M, Waldschmitt N, et al. Enterococcus hirae and Barnesiella intestinihominis facilitate cyclophosphamide-induced therapeutic immunomodulatory effects. Immunity 2016;45:931–43.
    • (2016) Immunity , vol.45 , pp. 931-943
    • Daillère, R.1    Vétizou, M.2    Waldschmitt, N.3
  • 71
    • 85033587326 scopus 로고    scopus 로고
    • Gut microbiome modulates response to anti-PD-1 immunotherapy in melanoma patients
    • Gopalakrishnan V, Spencer CN, Nezi L, et al. Gut microbiome modulates response to anti-PD-1 immunotherapy in melanoma patients. Science 2018;359:97–103.
    • (2018) Science , vol.359 , pp. 97-103
    • Gopalakrishnan, V.1    Spencer, C.N.2    Nezi, L.3
  • 72
    • 84948451779 scopus 로고    scopus 로고
    • Commensal Bifidobacterium promotes antitumor immunity and facilitates anti-PD-L1 efficacy
    • Sivan A, Corrales L, Hubert N, et al. Commensal Bifidobacterium promotes antitumor immunity and facilitates anti-PD-L1 efficacy. Science 2015;350:1084–9.
    • (2015) Science , vol.350 , pp. 1084-1089
    • Sivan, A.1    Corrales, L.2    Hubert, N.3
  • 73
    • 84948461699 scopus 로고    scopus 로고
    • Anticancer immunotherapy by CTLA-4 blockade relies on the gut microbiota
    • Vétizou M, Pitt JM, Daillère R, et al. Anticancer immunotherapy by CTLA-4 blockade relies on the gut microbiota. Science 2015;350:1079–84.
    • (2015) Science , vol.350 , pp. 1079-1084
    • Vétizou, M.1    Pitt, J.M.2    Daillère, R.3
  • 74
    • 85033576428 scopus 로고    scopus 로고
    • Gut microbiome influences efficacy of PD-1-based immunotherapy against epithelial tumors
    • Routy B, Le CE, Derosa L, et al. Gut microbiome influences efficacy of PD-1-based immunotherapy against epithelial tumors. Science 2018;359:91–7.
    • (2018) Science , vol.359 , pp. 91-97
    • Routy, B.1    Le, C.E.2    Derosa, L.3
  • 75
    • 84926409737 scopus 로고    scopus 로고
    • The microbiome of the urinary tract--a role beyond infection
    • Whiteside SA, Razvi H, Dave S, et al. The microbiome of the urinary tract--a role beyond infection. Nat Rev Urol 2015;12:81–90.
    • (2015) Nat Rev Urol , vol.12 , pp. 81-90
    • Whiteside, S.A.1    Razvi, H.2    Dave, S.3
  • 76
    • 84994740515 scopus 로고    scopus 로고
    • Gastric microbiota and carcinogenesis: the role of non-helicobacter pylori bacteria - a systematic review
    • Dias-Jácome E, Libânio D, Borges-Canha M, et al. Gastric microbiota and carcinogenesis: the role of non-helicobacter pylori bacteria - a systematic review. Rev Esp Enferm Dig 2016;108:530–40.
    • (2016) Rev Esp Enferm Dig , vol.108 , pp. 530-540
    • Dias-Jácome, E.1    Libânio, D.2    Borges-Canha, M.3
  • 77
    • 85040514150 scopus 로고    scopus 로고
    • Increased abundance of clostridium and fusobacterium in gastric microbiota of patients with gastric cancer in Taiwan
    • Hsieh YY, Tung SY, Pan HY, et al. Increased abundance of clostridium and fusobacterium in gastric microbiota of patients with gastric cancer in Taiwan. Sci Rep 2018;8:158.
    • (2018) Sci Rep , vol.8 , pp. 158
    • Hsieh, Y.Y.1    Tung, S.Y.2    Pan, H.Y.3
  • 78
    • 85043251326 scopus 로고    scopus 로고
    • Gastric microbial community profiling reveals a dysbiotic cancer-associated microbiota
    • Ferreira RM, Pereira-Marques J, Pinto-Ribeiro I, et al. Gastric microbial community profiling reveals a dysbiotic cancer-associated microbiota. Gut 2018;67:226–36.
    • (2018) Gut , vol.67 , pp. 226-236
    • Ferreira, R.M.1    Pereira-Marques, J.2    Pinto-Ribeiro, I.3
  • 79
    • 85035316104 scopus 로고    scopus 로고
    • Gastric cancer: the gastric microbiota - bacterial diversity and implications
    • Shah MA. Gastric cancer: the gastric microbiota - bacterial diversity and implications. Nat Rev Gastroenterol Hepatol 2017;14:692–3.
    • (2017) Nat Rev Gastroenterol Hepatol , vol.14 , pp. 692-693
    • Shah, M.A.1
  • 80
    • 85046682982 scopus 로고    scopus 로고
    • Helicobacter pylori eradication treatment and the risk of gastric adenocarcinoma in a Western population
    • Doorakkers E, Lagergren J, Engstrand L, et al. Helicobacter pylori eradication treatment and the risk of gastric adenocarcinoma in a Western population. Gut 2018;67:2092–2096.
    • (2018) Gut , vol.67 , pp. 2092-2096
    • Doorakkers, E.1    Lagergren, J.2    Engstrand, L.3
  • 81
    • 85044431681 scopus 로고    scopus 로고
    • Helicobacter pylori therapy for the prevention of Metachronous gastric cancer
    • Choi IJ, Kook MC, Kim YI, et al. Helicobacter pylori therapy for the prevention of Metachronous gastric cancer. N Engl J Med 2018;378:1085–95.
    • (2018) N Engl J Med , vol.378 , pp. 1085-1095
    • Choi, I.J.1    Kook, M.C.2    Kim, Y.I.3
  • 82
    • 33745593712 scopus 로고    scopus 로고
    • A possible role of Bacteroides fragilis enterotoxin in the aetiology of colorectal cancer
    • Toprak NU, Yagci A, Gulluoglu BM, et al. A possible role of Bacteroides fragilis enterotoxin in the aetiology of colorectal cancer. Clin Microbiol Infect 2006;12:782–6.
    • (2006) Clin Microbiol Infect , vol.12 , pp. 782-786
    • Toprak, N.U.1    Yagci, A.2    Gulluoglu, B.M.3
  • 83
    • 4644305046 scopus 로고    scopus 로고
    • Bacteroides fragilis enterotoxin induces intestinal epithelial cell secretion of interleukin-8 through mitogen-activated protein kinases and a tyrosine kinase-regulated nuclear factor-kappaB pathway
    • Wu S, Powell J, Mathioudakis N, et al. Bacteroides fragilis enterotoxin induces intestinal epithelial cell secretion of interleukin-8 through mitogen-activated protein kinases and a tyrosine kinase-regulated nuclear factor-kappaB pathway. Infect Immun 2004;72:5832–9.
    • (2004) Infect Immun , vol.72 , pp. 5832-5839
    • Wu, S.1    Powell, J.2    Mathioudakis, N.3
  • 84
    • 69949120571 scopus 로고    scopus 로고
    • A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses
    • Wu S, Rhee KJ, Albesiano E, et al. A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses. Nat Med 2009;15:1016–22.
    • (2009) Nat Med , vol.15 , pp. 1016-1022
    • Wu, S.1    Rhee, K.J.2    Albesiano, E.3
  • 85
    • 85018829135 scopus 로고    scopus 로고
    • Peptostreptococcus anaerobius induces intracellular cholesterol biosynthesis in colon cells to induce proliferation and causes dysplasia in mice
    • e5
    • Tsoi H, Esh C, Zhang X, et al. Peptostreptococcus anaerobius induces intracellular cholesterol biosynthesis in colon cells to induce proliferation and causes dysplasia in mice. Gastroenterology 2017;152:1419–33.e5.
    • (2017) Gastroenterology , vol.152 , pp. 1419-1433
    • Tsoi, H.1    Esh, C.2    Zhang, X.3
  • 86
    • 84942693814 scopus 로고    scopus 로고
    • Metagenomic analysis of faecal microbiome as a tool towards targeted non-invasive biomarkers for colorectal cancer
    • Yu J, Feng Q, Wong SH, et al. Metagenomic analysis of faecal microbiome as a tool towards targeted non-invasive biomarkers for colorectal cancer. Gut 2017;66:70–8.
    • (2017) Gut , vol.66 , pp. 70-78
    • Yu, J.1    Feng, Q.2    Wong, S.H.3
  • 87
    • 84942809028 scopus 로고    scopus 로고
    • Probiotics clostridium butyricum and Bacillus subtilis ameliorate intestinal tumorigenesis
    • Chen ZF, Ai LY, Wang JL, et al. Probiotics clostridium butyricum and Bacillus subtilis ameliorate intestinal tumorigenesis. Future Microbiol 2015;10:1433–45.
    • (2015) Future Microbiol , vol.10 , pp. 1433-1445
    • Chen, Z.F.1    Ai, L.Y.2    Wang, J.L.3
  • 88
    • 85034651295 scopus 로고    scopus 로고
    • Probiotic strain lactobacillus casei BL23 prevents colitis-associated colorectal cancer
    • Jacouton E, Chain F, Sokol H, et al. Probiotic strain lactobacillus casei BL23 prevents colitis-associated colorectal cancer. Front Immunol 2017;8:1553.
    • (2017) Front Immunol , vol.8 , pp. 1553
    • Jacouton, E.1    Chain, F.2    Sokol, H.3
  • 89
    • 84857656943 scopus 로고    scopus 로고
    • Preoperative probiotics decrease postoperative infectious complications of colorectal cancer
    • Zhang JW, Du P, Gao J, et al. Preoperative probiotics decrease postoperative infectious complications of colorectal cancer. Am J Med Sci 2012;343:199–205.
    • (2012) Am J Med Sci , vol.343 , pp. 199-205
    • Zhang, J.W.1    Du, P.2    Gao, J.3
  • 90
    • 84968813728 scopus 로고    scopus 로고
    • Effect of probiotics on small intestinal bacterial overgrowth in patients with gastric and colorectal cancer
    • Liang S, Xu L, Zhang D, et al. Effect of probiotics on small intestinal bacterial overgrowth in patients with gastric and colorectal cancer. Turk J Gastroenterol 2016;27:227–32.
    • (2016) Turk J Gastroenterol , vol.27 , pp. 227-232
    • Liang, S.1    Xu, L.2    Zhang, D.3
  • 91
    • 85031823110 scopus 로고    scopus 로고
    • Wild mouse gut microbiota promotes host fitness and improves disease resistance
    • e13
    • Rosshart SP, Vassallo BG, Angeletti D, et al. Wild mouse gut microbiota promotes host fitness and improves disease resistance. Cell 2017;171:1015–28.e13.
    • (2017) Cell , vol.171 , pp. 1015-1028
    • Rosshart, S.P.1    Vassallo, B.G.2    Angeletti, D.3
  • 92
    • 85032676174 scopus 로고    scopus 로고
    • Modulating bile acid pathways and TGR5 receptors for treating liver and GI diseases
    • Malhi H, Camilleri M. Modulating bile acid pathways and TGR5 receptors for treating liver and GI diseases. Curr Opin Pharmacol 2017;37:80–6.
    • (2017) Curr Opin Pharmacol , vol.37 , pp. 80-86
    • Malhi, H.1    Camilleri, M.2
  • 93
    • 85047415625 scopus 로고    scopus 로고
    • Gut microbiome-mediated bile acid metabolism regulates liver cancer via NKT cells
    • Ma C, Han M, Heinrich B, et al. Gut microbiome-mediated bile acid metabolism regulates liver cancer via NKT cells. Science 2018;360(6391):eaan5931.
    • (2018) Science , vol.360 , Issue.6391
    • Ma, C.1    Han, M.2    Heinrich, B.3
  • 94
    • 84922519617 scopus 로고    scopus 로고
    • Association between helicobacter spp. infections and hepatobiliary malignancies: a review
    • Segura-López FK, Güitrón-Cantú A, Torres J. Association between helicobacter spp. infections and hepatobiliary malignancies: a review. World J Gastroenterol 2015;21:1414–23.
    • (2015) World J Gastroenterol , vol.21 , pp. 1414-1423
    • Segura-López, F.K.1    Güitrón-Cantú, A.2    Torres, J.3
  • 95
    • 84899474318 scopus 로고    scopus 로고
    • Dysbiosis contributes to fibrogenesis in the course of chronic liver injury in mice
    • De Minicis S, Rychlicki C, Agostinelli L, et al. Dysbiosis contributes to fibrogenesis in the course of chronic liver injury in mice. Hepatology 2014;59:1738–49.
    • (2014) Hepatology , vol.59 , pp. 1738-1749
    • De Minicis, S.1    Rychlicki, C.2    Agostinelli, L.3
  • 96
    • 84954287816 scopus 로고    scopus 로고
    • Intestinal microbiota contributes to individual susceptibility to alcoholic liver disease
    • Llopis M, Cassard AM, Wrzosek L, et al. Intestinal microbiota contributes to individual susceptibility to alcoholic liver disease. Gut 2016;65:830–9.
    • (2016) Gut , vol.65 , pp. 830-839
    • Llopis, M.1    Cassard, A.M.2    Wrzosek, L.3
  • 97
    • 85038640540 scopus 로고    scopus 로고
    • Microbiota transplantation reveals beneficial impact of berberine on hepatotoxicity by improving gut homeostasis
    • [in press]
    • Qin C, Zhang H, Zhao L, et al. Microbiota transplantation reveals beneficial impact of berberine on hepatotoxicity by improving gut homeostasis. Sci China Life Sci 2017 [in press].
    • (2017) Sci China Life Sci
    • Qin, C.1    Zhang, H.2    Zhao, L.3
  • 98
    • 84913553798 scopus 로고    scopus 로고
    • Probiotic VSL#3 reduces liver disease severity and hospitalization in patients with cirrhosis: a randomized, controlled trial
    • e3
    • Dhiman RK, Rana B, Agrawal S, et al. Probiotic VSL#3 reduces liver disease severity and hospitalization in patients with cirrhosis: a randomized, controlled trial. Gastroenterology 2014;147:1327–37.e3.
    • (2014) Gastroenterology , vol.147 , pp. 1327-1337
    • Dhiman, R.K.1    Rana, B.2    Agrawal, S.3
  • 99
    • 84942791105 scopus 로고    scopus 로고
    • Effects of probiotics (cultured lactobacillus subtilis/streptococcus faecium) in the treatment of alcoholic hepatitis: randomized-controlled multicenter study
    • Han SH, Suk KT, Kim DJ, et al. Effects of probiotics (cultured lactobacillus subtilis/streptococcus faecium) in the treatment of alcoholic hepatitis: randomized-controlled multicenter study. Eur J Gastroenterol Hepatol 2015;27:1300–6.
    • (2015) Eur J Gastroenterol Hepatol , vol.27 , pp. 1300-1306
    • Han, S.H.1    Suk, K.T.2    Kim, D.J.3
  • 100
    • 85019222164 scopus 로고    scopus 로고
    • Total fecal microbiota transplantation alleviates high-fat diet-induced steatohepatitis in mice via beneficial regulation of gut microbiota
    • Zhou D, Pan Q, Shen F, et al. Total fecal microbiota transplantation alleviates high-fat diet-induced steatohepatitis in mice via beneficial regulation of gut microbiota. Sci Rep 2017;7:1529.
    • (2017) Sci Rep , vol.7 , pp. 1529
    • Zhou, D.1    Pan, Q.2    Shen, F.3
  • 101
    • 85009807664 scopus 로고    scopus 로고
    • Fecal microbiota manipulation prevents dysbiosis and alcohol-induced liver injury in mice
    • Ferrere G, Wrzosek L, Cailleux F, et al. Fecal microbiota manipulation prevents dysbiosis and alcohol-induced liver injury in mice. J Hepatol 2017;66:806–15.
    • (2017) J Hepatol , vol.66 , pp. 806-815
    • Ferrere, G.1    Wrzosek, L.2    Cailleux, F.3
  • 102
    • 85015667243 scopus 로고    scopus 로고
    • Healthy donor fecal microbiota transplantation in steroid-ineligible severe alcoholic hepatitis: a pilot study
    • Philips CA, Pande A, Shasthry SM, et al. Healthy donor fecal microbiota transplantation in steroid-ineligible severe alcoholic hepatitis: a pilot study. Clin Gastroenterol Hepatol 2017;15:600–2.
    • (2017) Clin Gastroenterol Hepatol , vol.15 , pp. 600-602
    • Philips, C.A.1    Pande, A.2    Shasthry, S.M.3
  • 103
    • 85034033801 scopus 로고    scopus 로고
    • Healthy donor faecal transplant for corticosteroid nonresponsive severe alcoholic hepatitis
    • Philips CA, Phadke N, Ganesan K, et al. Healthy donor faecal transplant for corticosteroid nonresponsive severe alcoholic hepatitis. BMJ Case Rep 2017;2017:bcr-2017–222310.
    • (2017) BMJ Case Rep
    • Philips, C.A.1    Phadke, N.2    Ganesan, K.3
  • 104
    • 85015729797 scopus 로고    scopus 로고
    • Fecal microbiota transplantation induces hepatitis B virus e-antigen (HBeAg) clearance in patients with positive HBeAg after long-term antiviral therapy
    • Ren YD, Ye ZS, Yang LZ, et al. Fecal microbiota transplantation induces hepatitis B virus e-antigen (HBeAg) clearance in patients with positive HBeAg after long-term antiviral therapy. Hepatology 2017;65:1765–8.
    • (2017) Hepatology , vol.65 , pp. 1765-1768
    • Ren, Y.D.1    Ye, Z.S.2    Yang, L.Z.3
  • 105
    • 85053430048 scopus 로고    scopus 로고
    • Antibiotic-associated disruption of microbiota composition and function in cirrhosis is restored by fecal transplant
    • Bajaj JS, Kakiyama G, Savidge T, et al. Antibiotic-associated disruption of microbiota composition and function in cirrhosis is restored by fecal transplant. Hepatology 2018;68(4):1549–1558.
    • (2018) Hepatology , vol.68 , Issue.4 , pp. 1549-1558
    • Bajaj, J.S.1    Kakiyama, G.2    Savidge, T.3
  • 106
    • 85031320898 scopus 로고    scopus 로고
    • Fecal microbiota transplantation prevents hepatic encephalopathy in rats with carbon tetrachloride-induced acute hepatic dysfunction
    • Wang WW, Zhang Y, Huang XB, et al. Fecal microbiota transplantation prevents hepatic encephalopathy in rats with carbon tetrachloride-induced acute hepatic dysfunction. World J Gastroenterol 2017;23:6983–94.
    • (2017) World J Gastroenterol , vol.23 , pp. 6983-6994
    • Wang, W.W.1    Zhang, Y.2    Huang, X.B.3
  • 107
    • 84952638786 scopus 로고    scopus 로고
    • Fecal microbiota transplantation in the management of hepatic encephalopathy
    • Kao D, Roach B, Park H, et al. Fecal microbiota transplantation in the management of hepatic encephalopathy. Hepatology 2016;63:339–40.
    • (2016) Hepatology , vol.63 , pp. 339-340
    • Kao, D.1    Roach, B.2    Park, H.3
  • 108
    • 85026856382 scopus 로고    scopus 로고
    • Fecal microbiota transplant from a rational stool donor improves hepatic encephalopathy: a randomized clinical trial
    • Bajaj JS, Kassam Z, Fagan A, et al. Fecal microbiota transplant from a rational stool donor improves hepatic encephalopathy: a randomized clinical trial. Hepatology 2017;66:1727–38.
    • (2017) Hepatology , vol.66 , pp. 1727-1738
    • Bajaj, J.S.1    Kassam, Z.2    Fagan, A.3
  • 109
    • 84885093561 scopus 로고    scopus 로고
    • Role of bacterial infections in pancreatic cancer
    • Michaud DS. Role of bacterial infections in pancreatic cancer. Carcinogenesis 2013;34:2193–7.
    • (2013) Carcinogenesis , vol.34 , pp. 2193-2197
    • Michaud, D.S.1
  • 110
    • 84866372497 scopus 로고    scopus 로고
    • MyD88 inhibition amplifies dendritic cell capacity to promote pancreatic carcinogenesis via Th2 cells
    • Ochi A, Nguyen AH, Bedrosian AS, et al. MyD88 inhibition amplifies dendritic cell capacity to promote pancreatic carcinogenesis via Th2 cells. J Exp Med 2012;209:1671–87.
    • (2012) J Exp Med , vol.209 , pp. 1671-1687
    • Ochi, A.1    Nguyen, A.H.2    Bedrosian, A.S.3
  • 111
    • 85029481879 scopus 로고    scopus 로고
    • Potential role of intratumor bacteria in mediating tumor resistance to the chemotherapeutic drug gemcitabine
    • Geller LT, Barzily-Rokni M, Danino T, et al. Potential role of intratumor bacteria in mediating tumor resistance to the chemotherapeutic drug gemcitabine. Science 2017;357:1156–60.
    • (2017) Science , vol.357 , pp. 1156-1160
    • Geller, L.T.1    Barzily-Rokni, M.2    Danino, T.3
  • 112
    • 84992055617 scopus 로고    scopus 로고
    • Human oral microbiome and prospective risk for pancreatic cancer: a population-based nested case-control study
    • Fan X, Alekseyenko AV, Wu J, et al. Human oral microbiome and prospective risk for pancreatic cancer: a population-based nested case-control study. Gut 2018;67:120–7.
    • (2018) Gut , vol.67 , pp. 120-127
    • Fan, X.1    Alekseyenko, A.V.2    Wu, J.3
  • 113
    • 84927138939 scopus 로고    scopus 로고
    • Association of Fusobacterium species in pancreatic cancer tissues with molecular features and prognosis
    • Mitsuhashi K, Nosho K, Sukawa Y, et al. Association of Fusobacterium species in pancreatic cancer tissues with molecular features and prognosis. Oncotarget 2015;6:7209–20.
    • (2015) Oncotarget , vol.6 , pp. 7209-7220
    • Mitsuhashi, K.1    Nosho, K.2    Sukawa, Y.3
  • 114
    • 85047056415 scopus 로고    scopus 로고
    • The pancreatic cancer microbiome promotes oncogenesis by induction of innate and adaptive immune suppression
    • Pushalkar S, Hundeyin M, Daley D, et al. The pancreatic cancer microbiome promotes oncogenesis by induction of innate and adaptive immune suppression. Cancer Discov 2018;8:403–16.
    • (2018) Cancer Discov , vol.8 , pp. 403-416
    • Pushalkar, S.1    Hundeyin, M.2    Daley, D.3
  • 115
    • 0015243561 scopus 로고
    • Gut bacteria and aetiology of cancer of the breast
    • Hill MJ, Goddard P, Williams RE. Gut bacteria and aetiology of cancer of the breast. Lancet 1971;2:472–3.
    • (1971) Lancet , vol.2 , pp. 472-473
    • Hill, M.J.1    Goddard, P.2    Williams, R.E.3
  • 116
    • 85042362092 scopus 로고    scopus 로고
    • Postmenopausal breast cancer and oestrogen associations with the IgA-coated and IgA-noncoated faecal microbiota
    • Goedert JJ, Hua X, Bielecka A, et al. Postmenopausal breast cancer and oestrogen associations with the IgA-coated and IgA-noncoated faecal microbiota. Br J Cancer 2018;118:471–9.
    • (2018) Br J Cancer , vol.118 , pp. 471-479
    • Goedert, J.J.1    Hua, X.2    Bielecka, A.3
  • 117
    • 84990955080 scopus 로고    scopus 로고
    • Gastrointestinal microbiome and breast cancer: correlations, mechanisms and potential clinical implications
    • Yang J, Tan Q, Fu Q, et al. Gastrointestinal microbiome and breast cancer: correlations, mechanisms and potential clinical implications. Breast Cancer 2017;24:220–8.
    • (2017) Breast Cancer , vol.24 , pp. 220-228
    • Yang, J.1    Tan, Q.2    Fu, Q.3
  • 118
    • 84878233113 scopus 로고    scopus 로고
    • Lactobacillus acidophilus could modulate the immune response against breast cancer in murine model
    • Maroof H, Hassan ZM, Mobarez AM, et al. Lactobacillus acidophilus could modulate the immune response against breast cancer in murine model. J Clin Immunol 2012;32:1353–9.
    • (2012) J Clin Immunol , vol.32 , pp. 1353-1359
    • Maroof, H.1    Hassan, Z.M.2    Mobarez, A.M.3
  • 119
    • 85031736103 scopus 로고    scopus 로고
    • Metagenomic shotgun sequencing and unbiased Metabolomic profiling identify specific human gut microbiota and metabolites associated with immune checkpoint therapy efficacy in melanoma patients
    • Frankel AE, Coughlin LA, Kim J, et al. Metagenomic shotgun sequencing and unbiased Metabolomic profiling identify specific human gut microbiota and metabolites associated with immune checkpoint therapy efficacy in melanoma patients. Neoplasia 2017;19:848–55.
    • (2017) Neoplasia , vol.19 , pp. 848-855
    • Frankel, A.E.1    Coughlin, L.A.2    Kim, J.3
  • 120
    • 85042654568 scopus 로고    scopus 로고
    • Oncologists tap the microbiome in bid to improve immunotherapy outcomes
    • Mullard A. Oncologists tap the microbiome in bid to improve immunotherapy outcomes. Nat Rev Drug Discov 2018;17:153–5.
    • (2018) Nat Rev Drug Discov , vol.17 , pp. 153-155
    • Mullard, A.1
  • 121
    • 84885629462 scopus 로고    scopus 로고
    • Excess risk of Clostridium difficile infection in ovarian cancer is related to exposure to broad-spectrum antibiotics
    • Kim JS, Ward KK, Shah NR, et al. Excess risk of Clostridium difficile infection in ovarian cancer is related to exposure to broad-spectrum antibiotics. Support Care Cancer 2013;21:3103–7.
    • (2013) Support Care Cancer , vol.21 , pp. 3103-3107
    • Kim, J.S.1    Ward, K.K.2    Shah, N.R.3
  • 122
    • 85037677159 scopus 로고    scopus 로고
    • Safety and efficacy of fecal microbiota transplant for recurrent Clostridium difficile infection in patients with cancer treated with cytotoxic chemotherapy: a single-institution retrospective case series
    • Hefazi M, Patnaik MM, Hogan WJ, et al. Safety and efficacy of fecal microbiota transplant for recurrent Clostridium difficile infection in patients with cancer treated with cytotoxic chemotherapy: a single-institution retrospective case series. Mayo Clin Proc 2017;92:1617–24.
    • (2017) Mayo Clin Proc , vol.92 , pp. 1617-1624
    • Hefazi, M.1    Patnaik, M.M.2    Hogan, W.J.3
  • 123
    • 84903894091 scopus 로고    scopus 로고
    • Fecal microbiota transplant for treatment of Clostridium difficile infection in immunocompromised patients
    • Kelly CR, Ihunnah C, Fischer M, et al. Fecal microbiota transplant for treatment of Clostridium difficile infection in immunocompromised patients. Am J Gastroenterol 2014;109:1065–71.
    • (2014) Am J Gastroenterol , vol.109 , pp. 1065-1071
    • Kelly, C.R.1    Ihunnah, C.2    Fischer, M.3
  • 124
    • 84922188642 scopus 로고    scopus 로고
    • Fecal microbiota transplantation in patients with cancer undergoing treatment
    • Blackburn LM, Bales A, Caldwell M, et al. Fecal microbiota transplantation in patients with cancer undergoing treatment. Clin J Oncol Nurs 2015;19:111–4.
    • (2015) Clin J Oncol Nurs , vol.19 , pp. 111-114
    • Blackburn, L.M.1    Bales, A.2    Caldwell, M.3
  • 125
    • 84923873423 scopus 로고    scopus 로고
    • A different kind of "allogeneic transplant": successful fecal microbiota transplant for recurrent and refractory Clostridium difficile infection in a patient with relapsed aggressive B-cell lymphoma
    • Trubiano JA, George A, Barnett J, et al. A different kind of "allogeneic transplant": successful fecal microbiota transplant for recurrent and refractory Clostridium difficile infection in a patient with relapsed aggressive B-cell lymphoma. Leuk Lymphoma 2015;56:512–4.
    • (2015) Leuk Lymphoma , vol.56 , pp. 512-514
    • Trubiano, J.A.1    George, A.2    Barnett, J.3
  • 126
    • 84934845392 scopus 로고    scopus 로고
    • Fecal microbiota transplant for recurrent Clostridium difficile infection after peripheral autologous stem cell transplant for diffuse large B-cell lymphoma
    • Mittal C, Miller N, Meighani A, et al. Fecal microbiota transplant for recurrent Clostridium difficile infection after peripheral autologous stem cell transplant for diffuse large B-cell lymphoma. Bone Marrow Transplant 2015;50:1010.
    • (2015) Bone Marrow Transplant , vol.50 , pp. 1010
    • Mittal, C.1    Miller, N.2    Meighani, A.3
  • 127
    • 84871026100 scopus 로고    scopus 로고
    • Fecal microbiota transplantation for fulminant Clostridium difficile infection in an allogeneic stem cell transplant patient
    • Neemann K, Eichele DD, Smith PW, et al. Fecal microbiota transplantation for fulminant Clostridium difficile infection in an allogeneic stem cell transplant patient. Transpl Infect Dis 2012;14:E161–5.
    • (2012) Transpl Infect Dis , vol.14 , pp. E161-E165
    • Neemann, K.1    Eichele, D.D.2    Smith, P.W.3
  • 128
    • 84920687911 scopus 로고    scopus 로고
    • Fecal microbiota transplant after hematopoietic SCT: report of a successful case
    • de Castro CG, Ganc AJ, Ganc RL, et al. Fecal microbiota transplant after hematopoietic SCT: report of a successful case. Bone Marrow Transplant 2015;50:145.
    • (2015) Bone Marrow Transplant , vol.50 , pp. 145
    • de Castro, C.G.1    Ganc, A.J.2    Ganc, R.L.3
  • 129
    • 84981164544 scopus 로고    scopus 로고
    • Fecal microbiota transplantation for recurrent Clostridium difficile infection in hematopoietic stem cell transplant recipients
    • Webb BJ, Brunner A, Ford CD, et al. Fecal microbiota transplantation for recurrent Clostridium difficile infection in hematopoietic stem cell transplant recipients. Transpl Infect Dis 2016;18:628–33.
    • (2016) Transpl Infect Dis , vol.18 , pp. 628-633
    • Webb, B.J.1    Brunner, A.2    Ford, C.D.3
  • 130
    • 85030684961 scopus 로고    scopus 로고
    • Faecal microbiota transplant: a novel biological approach to extensively drug-resistant organism-related non-relapse mortality
    • Innes AJ, Mullish BH, Fernando F, et al. Faecal microbiota transplant: a novel biological approach to extensively drug-resistant organism-related non-relapse mortality. Bone Marrow Transplant 2017;52:1452–4.
    • (2017) Bone Marrow Transplant , vol.52 , pp. 1452-1454
    • Innes, A.J.1    Mullish, B.H.2    Fernando, F.3
  • 131
    • 85038382140 scopus 로고    scopus 로고
    • Radiation induces proinflammatory dysbiosis: transmission of inflammatory susceptibility by host cytokine induction
    • Gerassy-Vainberg S, Blatt A, Danin-Poleg Y, et al. Radiation induces proinflammatory dysbiosis: transmission of inflammatory susceptibility by host cytokine induction. Gut 2018;67:97–107.
    • (2018) Gut , vol.67 , pp. 97-107
    • Gerassy-Vainberg, S.1    Blatt, A.2    Danin-Poleg, Y.3
  • 132
    • 85013950312 scopus 로고    scopus 로고
    • Faecal microbiota transplantation protects against radiation-induced toxicity
    • Cui M, Xiao H, Li Y, et al. Faecal microbiota transplantation protects against radiation-induced toxicity. EMBO Mol Med 2017;9:448–61.
    • (2017) EMBO Mol Med , vol.9 , pp. 448-461
    • Cui, M.1    Xiao, H.2    Li, Y.3
  • 133
    • 85015216239 scopus 로고    scopus 로고
    • The intestinal microbiota in allogeneic hematopoietic cell transplant and graft-versus-host disease
    • Staffas A, Dsm B, van den Brink MR. The intestinal microbiota in allogeneic hematopoietic cell transplant and graft-versus-host disease. Blood 2017;129:927–33.
    • (2017) Blood , vol.129 , pp. 927-933
    • Staffas, A.1    Dsm, B.2    van den Brink, M.R.3
  • 134
    • 84905974289 scopus 로고    scopus 로고
    • The effects of intestinal tract bacterial diversity on mortality following allogeneic hematopoietic stem cell transplantation
    • Taur Y, Jenq RR, Perales MA, et al. The effects of intestinal tract bacterial diversity on mortality following allogeneic hematopoietic stem cell transplantation. Blood 2014;124:1174–82.
    • (2014) Blood , vol.124 , pp. 1174-1182
    • Taur, Y.1    Jenq, R.R.2    Perales, M.A.3
  • 135
    • 84992074418 scopus 로고    scopus 로고
    • Fecal microbiota transplantation for patients with steroid-resistant acute graft-versus-host disease of the gut
    • Kakihana K, Fujioka Y, Suda W, et al. Fecal microbiota transplantation for patients with steroid-resistant acute graft-versus-host disease of the gut. Blood 2016;128:2083–8.
    • (2016) Blood , vol.128 , pp. 2083-2088
    • Kakihana, K.1    Fujioka, Y.2    Suda, W.3
  • 136
    • 84975125454 scopus 로고    scopus 로고
    • MICROBIOME RESEARCH. Banking on stool despite an uncertain future
    • Amirtha T. MICROBIOME RESEARCH. Banking on stool despite an uncertain future. Science 2016;352:1261–2.
    • (2016) Science , vol.352 , pp. 1261-1262
    • Amirtha, T.1
  • 137
    • 85046032348 scopus 로고    scopus 로고
    • Searching for superstool: maximizing the therapeutic potential of FMT
    • Olesen SW, Leier MM, Alm EJ, et al. Searching for superstool: maximizing the therapeutic potential of FMT. Nat Rev Gastroenterol Hepatol 2018;15:387–8.
    • (2018) Nat Rev Gastroenterol Hepatol , vol.15 , pp. 387-388
    • Olesen, S.W.1    Leier, M.M.2    Alm, E.J.3
  • 138
    • 84984924453 scopus 로고    scopus 로고
    • Systematic review: adverse events of fecal microbiota transplantation
    • Wang S, Xu M, Wang W, et al. Systematic review: adverse events of fecal microbiota transplantation. PLoS One 2016;11:e0161174.
    • (2016) PLoS One , vol.11
    • Wang, S.1    Xu, M.2    Wang, W.3
  • 139
    • 84881148330 scopus 로고    scopus 로고
    • Norovirus gastroenteritis after fecal microbiota transplantation for treatment of Clostridium difficile infection despite asymptomatic donors and lack of sick contacts
    • Schwartz M, Gluck M, Koon S. Norovirus gastroenteritis after fecal microbiota transplantation for treatment of Clostridium difficile infection despite asymptomatic donors and lack of sick contacts. Am J Gastroenterol 2013;108:1367.
    • (2013) Am J Gastroenterol , vol.108 , pp. 1367
    • Schwartz, M.1    Gluck, M.2    Koon, S.3


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