Commensal Bifidobacterium promotes antitumor immunity and facilitates anti-PD-L1 efficacy

Science

Volumn 350, Issue 6264, 2015, Pages 1084-1089

  Sivan, Ayelet ^a   Corrales, Leticia ^a   Hubert, Nathaniel ^a   Williams, Jason B ^a   Aquino Michaels, Keston ^a   Earley, Zachary M ^a   Benyamin, Franco W ^a   Lei, Yuk Man ^a   Jabri, Bana ^a   Alegre, Maria Luisa ^a   Chang, Eugene B ^a   Gajewski, Thomas F ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; ANTINEOPLASTIC AGENT; PROBIOTIC AGENT; PROGRAMMED CELL DEATH PROTEIN 1 LIGAND 1 SPECIFIC ANTIBODY; RIBOSOME RNA; UNCLASSIFIED DRUG; MONOCLONAL ANTIBODY; PROGRAMMED DEATH 1 LIGAND 1; RNA 16S;

ANTIBODY; BACTERIUM; COMMENSAL; GENETIC ANALYSIS; HISTOPATHOLOGY; IMMUNE RESPONSE; RODENT; TUMOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BIFIDOBACTERIUM; CANCER CONTROL; CANCER GROWTH; CANCER IMMUNOTHERAPY; CD8+ T LYMPHOCYTE; CELL FUNCTION; COMMENSAL; CONTROLLED STUDY; DENDRITIC CELL; MELANOMA; MICROFLORA; MOUSE; NONHUMAN; PRIORITY JOURNAL; RNA SEQUENCE; THERAPY EFFECT; TUMOR IMMUNITY; TUMOR MICROENVIRONMENT; ANIMAL; C57BL MOUSE; FECAL MICROBIOTA TRANSPLANTATION; GENE EXPRESSION REGULATION; GENETICS; HUMAN; IMMUNITY; IMMUNOLOGY; IMMUNOTHERAPY; INTESTINE FLORA; LYMPHOCYTE ACTIVATION; PROCEDURES; SKIN NEOPLASMS; SYMBIOSIS; T LYMPHOCYTE;

BIFIDOBACTERIUM; MUS;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD274; BIFIDOBACTERIUM; CD8-POSITIVE T-LYMPHOCYTES; DENDRITIC CELLS; FECAL MICROBIOTA TRANSPLANTATION; GASTROINTESTINAL MICROBIOME; GENE EXPRESSION REGULATION; HUMANS; IMMUNITY; IMMUNOTHERAPY; LYMPHOCYTE ACTIVATION; MELANOMA; MICE; MICE, INBRED C57BL; RNA, RIBOSOMAL, 16S; SKIN NEOPLASMS; SYMBIOSIS; T-LYMPHOCYTES; TUMOR MICROENVIRONMENT;

EID: 84948451779     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aac4255     Document Type: Article

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