Infection, antibiotic therapy and risk of colorectal cancer: A nationwide nested case-control study in patients with Type 2 diabetes mellitus

International Journal of Cancer

Volumn 135, Issue 4, 2014, Pages 956-967

  Wang, Jiun Ling ^a   Chang, Chia Hsuin ^b,c,d   Lin, Jou Wei ^c,d   Wu, Li Chiu ^b   Chuang, Lee Ming ^b,c,d   Lai, Mei Shu ^b  

^a E DA HOSPITAL   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^c NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^d NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

antibiotics; colon neoplasms; diabetes mellitus; intra abdominal infection; rectal neoplasms

Indexed keywords

ANTIBIOTIC AGENT; CARBAPENEM DERIVATIVE; CEPHALOSPORIN DERIVATIVE; CEPHAMYCIN; IMIDAZOLE DERIVATIVE; LINCOSAMIDE;

ABDOMINAL INFECTION; ADULT; AGED; ANTIBIOTIC THERAPY; ARTICLE; BONE INFECTION; CANCER INCIDENCE; CANCER RISK; CASE CONTROL STUDY; COHORT ANALYSIS; COLORECTAL CANCER; CONTROLLED STUDY; DISEASE ASSOCIATION; DOSE RESPONSE; DRUG USE; FEMALE; HUMAN; INFECTIOUS ARTHRITIS; LOWER RESPIRATORY TRACT INFECTION; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; SEPTICEMIA; SKIN INFECTION; SOFT TISSUE INFECTION; TAIWAN; UROGENITAL TRACT INFECTION; WOUND INFECTION;

ANTIBIOTICS; COLON NEOPLASMS; DIABETES MELLITUS; INTRA-ABDOMINAL INFECTION; RECTAL NEOPLASMS;

AGED; ALGORITHMS; ANTI-BACTERIAL AGENTS; BACTERIAL INFECTIONS; CASE-CONTROL STUDIES; COHORT STUDIES; COLORECTAL NEOPLASMS; COMORBIDITY; DIABETES COMPLICATIONS; DIABETES MELLITUS, TYPE 2; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; INCIDENCE; MALE; MIDDLE AGED; ODDS RATIO; REGRESSION ANALYSIS; REPRODUCIBILITY OF RESULTS; RISK FACTORS; TAIWAN;

EID: 84902291887     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.28738     Document Type: Article

References (28)

1. Siegel RL, Ward EM, Jemal A,. Trends in colorectal cancer incidence rates in the United States by tumor location and stage, 1992-2008. Cancer Epidemiol Biomarkers Prev 2012; 21: 411-16.
2. Aune D, Chan DS, Lau R, et al. Dietary fibre, whole |grains, and risk of colorectal cancer: systematic review and dose-response meta-analysis of prospective studies. BMJ 2011; 343: d6617.
3. Erbach M, Mehnert H, Schnell O,. Diabetes and the risk for colorectal cancer. J Diabetes Complications 2012; 26: 50-5.
4. Lin HL, Lin HC, Lin CC,. Increased risk of colorectal cancer among patients with biliary tract inflammation: a 5-year follow-up study. Int J Cancer 2011; 128: 447-52.
5. Lai HC, Lin CC, Cheng KS, et al. Increased incidence of gastrointestinal cancers among patients with pyogenic liver abscess: a population-based cohort study. Gastroenterology 2014; 146: 129-37.
6. Willing BP, Gill N, Finlay BB,. The role of the immune system in regulating the microbiota. Gut Microbes 2010; 1: 213-23.
7. Pala V, Sieri S, Berrino F, et al. Yogurt consumption and risk of colorectal cancer in the Italian European prospective investigation into cancer and nutrition cohort. Int J Cancer 2011; 129: 2712-19.
8. Rafter J, Bennett M, Caderni G, et al. Dietary synbiotics reduce cancer risk factors in polypectomized and colon cancer patients. Am J Clin Nutr 2007; 85: 488-96.
9. Ubeda C, Pamer EG,. Antibiotics, microbiota, and immune defense. Trends Immunol 2012; 33: 459-66.
10. Chang CH, Lin JW, Wu LC, et al. Angiotensin receptor blockade and risk of cancer in type 2 diabetes mellitus: a nationwide case-control study. J Clin Oncol 2011; 29: 3001-7.
11. Chang CH, Lin JW, Wu LC, et al. Association of thiazolidinediones with liver cancer and colorectal cancer in type 2 diabetes mellitus. Hepatology 2012; 55: 1462-72.
12. Brook I,. Antimicrobial treatment of anaerobic infections. Expert Opin Pharmacother 2011; 12: 1691-707.
13. Kilkkinen A, Rissanen H, Klaukka T, et al. Antibiotic use predicts an increased risk of cancer. Int J Cancer 2008; 123: 2152-5.
14. Boleij A, Tjalsma H,. Gut bacteria in health and disease: a survey on the interface between intestinal microbiology and colorectal cancer. Biol Rev Camb Philos Soc 2012; 87: 701-30.
15. Neish AS,. Microbes in gastrointestinal health and disease. Gastroenterology 2009; 136: 65-80.
16. Khazaie K, Zadeh M, Khan MW, et al. Abating colon cancer polyposis by Lactobacillus acidophilus deficient in lipoteichoic acid. Proc Natl Acad Sci USA 2012; 109: 10462-7.
17. Willing BP, Russell SL, Finlay BB,. Shifting the balance: antibiotic effects on host-microbiota mutualism. Nat Rev Microbiol 2011; 9: 233-43.
18. Jernberg C, Lofmark S, Edlund C, et al. Long-term impacts of antibiotic exposure on the human intestinal microbiota. Microbiology 2010; 156: 3216-23.
19. Shen XJ, Rawls JF, Randall T, et al. Molecular characterization of mucosal adherent bacteria and associations with colorectal adenomas. Gut Microbes 2010; 1: 138-47.
20. Pagnini C, Corleto VD, Mangoni ML, et al. Alteration of local microflora and α-defensins hyper-production in colonic adenoma mucosa. J Clin Gastroenterol 2011; 45: 602-10.
21. Krook A, Kjellander J, Danielsson D,. Susceptibility of bacteroides species to metronidazole during treatment of patients with Crohn's disease and healthy individuals. Scand J Infect Dis 1982; 14: 45-8.
22. Wu S, Rhee KJ, Albesiano E, et al. A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses. Nat Med 2009; 15: 1016-22.
23. Bendesky A, Menendez D, Ostrosky-Wegman P,. Is metronidazole carcinogenic? Mutat Res 2002; 511: 133-44.
24. Friedman GD, Jiang SF, Udaltsova N, et al. Epidemiologic evaluation of pharmaceuticals with limited evidence of carcinogenicity. Int J Cancer 2009; 125: 2173-8.
25. Falagas ME, Walker AM, Jick H, et al. Late incidence of cancer after metronidazole use: a matched metronidazole user/nonuser study. Clin Infect Dis 1998; 26: 384-8.
26. Thapa PB, Whitlock JA, Brockman Worrell KG, et al. Prenatal exposure to metronidazole and risk of childhood cancer: a retrospective cohort study of children younger than 5 years. Cancer 1998; 83: 1461-8.
27. National Toxicology Program. Metronidazole. Rep Carcinog 2011; 12: 269-70.
28. Boleij A, van Gelder MM, Swinkels DW, et al. Clinical Importance of Streptococcus gallolyticus infection among colorectal cancer patients: systematic review and meta-analysis. Clin Infect Dis 2011; 53: 870-8.