Healthy Donor Fecal Microbiota Transplantation in Steroid-Ineligible Severe Alcoholic Hepatitis: A Pilot Study

Clinical Gastroenterology and Hepatology

Volumn 15, Issue 4, 2017, Pages 600-602

  Philips, Cyriac Abby ^a   Pande, Apurva ^a   Shasthry, S Murali ^a   Jamwal, Kapil Dev ^a   Khillan, Vikas ^a   Chandel, Shivendra Singh ^a   Kumar, Guresh ^a   Sharma, Manoj K ^a   Maiwall, Rakhi ^a   Jindal, Ankur ^a   Choudhary, Ashok ^a   Hussain, Md Shabbir ^a   Sharma, Shvetank ^a   Sarin, Shiv K ^a  

^a INSTITUTE OF LIVER AND BILIARY SCIENCES   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTATE AMINOTRANSFERASE; BILIRUBIN; SODIUM;

ACTINOBACTERIA; ALCOHOL LIVER DISEASE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BACTERIAL INVASION; BACTERIAL PHENOMENA AND FUNCTIONS; BIFIDOBACTERIUM LONGUM; BIOINFORMATICS; CHILD PUGH SCORE; CLINICAL EFFECTIVENESS; COMPARATIVE STUDY; DIGESTIVE TUBE; DONOR; DOWN REGULATION; DYSBIOSIS; ENTEROCOCCUS; ENTEROCOCCUS VILLORUM; EPITHELIUM CELL; ESCHERICHIA COLI; FECAL MICROBIOTA TRANSPLANTATION; FECES ANALYSIS; FLATULENCE; FOLLOW UP; HEALTHY DONOR; HEPATIC ENCEPHALOPATHY; HUMAN; KLEBSIELLA PNEUMONIAE; MEGASPHAERA ELSDENII; METABOLISM; METHANE METABOLISM; MICROBIAL COMMUNITY; MODEL FOR END STAGE LIVER DISEASE SCORE; NASODUODENAL TUBE; NONHUMAN; OUTCOME ASSESSMENT; PATIENT SAFETY; PILOT STUDY; POPULATION ABUNDANCE; PROTEOBACTERIA; SHORT SURVEY; SPECIES DIVERSITY; STEROID INELIGIBLE SEVERE ALCOHOLIC HEPATITIS; SURVIVAL RATE; UPREGULATION; COMPLICATION; INTESTINE FLORA; MALE; PROCEDURES; TREATMENT OUTCOME;

DYSBIOSIS; FECAL MICROBIOTA TRANSPLANTATION; GASTROINTESTINAL MICROBIOME; HEPATITIS, ALCOHOLIC; HUMANS; MALE; PILOT PROJECTS; TREATMENT OUTCOME;

EID: 85015667243     PISSN: 15423565     EISSN: 15427714     Source Type: Journal    
DOI: 10.1016/j.cgh.2016.10.029     Document Type: Short Survey

References (8)

1. 1 Casanova, J., Bataller, R., Alcoholic hepatitis: prognosis and treatment. Gastroenterol Hepatol 37 (2014), 262–268.
2. 2 Chen, Y., Ji, F., Guo, J., et al. Dysbiosis of small intestinal microbiota in liver cirrhosis and its association with etiology. Sci Rep 34055 (2016), 1–9.
3. 3 Llopis, M., Cassard, A.M., Wrzosek, L., et al. Intestinal microbiota contributes to individual susceptibility to alcoholic liver disease. Gut 65 (2016), 830–839.
4. 4 Kennedy, N.A., Walker, A.W., Berry, S.H., et al. The impact of different DNA extraction kits and laboratories upon the assessment of human gut microbiota composition by 16S rRNA gene sequencing. PLoS One, 9, 2014, e88982.
5. 5 DeSantis, T.Z., Hugenholtz, P., Larsen, N., et al. Greengenes, a chimera-checked 16S rRNA gene database and workbench compatible with ARB. Appl Environ Microbiol 72 (2006), 5069–5072.
6. 6 Langille, M.G.I., et al. Predictive functional profiling of microbial communities using 16S rRNA marker gene sequences. Nat Biotechnol 31 (2013), 814–821.
7. 7 Li, S.S., Zhu, A., Benes, V., et al. Durable coexistence of donor and recipient strains after fecal microbiota transplantation. Science 352 (2016), 586–589.
8. 8 Song, S.J., Lauber, C., Costello, E.K., et al. Cohabiting family members share microbiota with one another and with their dogs. eLife, 2, 2013, e00458.