Potential role of Escherichia coli DNA mismatch repair proteins in colon cancer

Critical Reviews in Oncology/Hematology

Volumn 96, Issue 3, 2015, Pages 475-482

  Khan, Shahanavaj ^a  

^a KING SAUD UNIVERSITY   (Saudi Arabia)

Author keywords

Aetiology; CRC; DNA repair genes; E. coli; In silico; Protein targeting

Indexed keywords

BACTERIAL TOXIN; CYCLE INHIBITING FACTOR; CYTOLETHAL DISTENDING TOXIN; CYTOTOXIC NECROTIZING FACTOR; CYTOTOXIN; DNA GLYCOSYLASE MUTY; POLYKETIDE SYNTHASE; PROTEIN MUTL; PROTEIN MUTS; UNCLASSIFIED DRUG; DNA LIGASE; ESCHERICHIA COLI PROTEIN;

AMINO ACID SEQUENCE; BACTERIAL COLONIZATION; BACTERIAL STRAIN; CANCER GROWTH; CELL CYCLE; CELL NUCLEUS; COLON CARCINOGENESIS; COLON MUCOSA; COLORECTAL CANCER; COLORECTAL CANCER CELL LINE; COMPUTER MODEL; CROHN DISEASE; ENTEROPATHOGENIC ESCHERICHIA COLI; EPIGENETICS; GENE MUTATION; GENE OVEREXPRESSION; GENETIC ASSOCIATION; GENETIC REGULATION; HORIZONTAL GENE TRANSFER; HOST CELL; HUMAN; INTRACELLULAR SPACE; MUTL GENE; MUTS GENE; MUTY GENE; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; PREDICTION; PROTEIN ANALYSIS; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; REVIEW; SEQUENCE HOMOLOGY; ULCERATIVE COLITIS; ANIMAL; COLON TUMOR; ESCHERICHIA COLI; GROWTH, DEVELOPMENT AND AGING; HOST PATHOGEN INTERACTION; METABOLISM; MICROBIOLOGY; PATHOLOGY;

ANIMALS; COLONIC NEOPLASMS; DNA REPAIR ENZYMES; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; HOST-PATHOGEN INTERACTIONS; HUMANS;

EID: 84983143348     PISSN: 10408428     EISSN: 18790461     Source Type: Journal    
DOI: 10.1016/j.critrevonc.2015.05.002     Document Type: Review

References (82)

1. Acharya S., Foster P.L., Brooks P., Fishel R. The coordinated functions of the E. coli MutS and MutL proteins in mismatch repair. Mol Cell 2003, 12:233-246.
2. Antonic V., Stojadinovic A., Kester K.E., et al. Significance of infectious agents in colorectal cancer development. J Cancer 2013, 4:227-240.
3. Arthur J.C., Perez-Chanona E., Muhlbauer M., et al. Intestinal inflammation targets cancer-inducing activity of the microbiota. Science 2012, 338:120-123.
4. Barnich N., Carvalho F.A., Glasser A.L., et al. CEACAM6 acts as a receptor for adherent-invasive E. coli, supporting ileal mucosa colonization in Crohn disease. J Clin Invest 2007, 117:1566-1574.
5. Baylin S.B., Esteller M., Rountree M.R., Bachman K.E., Schuebel K., Herman J.G. Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer. Hum Mol Genet 2001, 10:687-692.
6. Bonnet M., Buc E., Sauvanet P., et al. Colonization of the human gut by E. coli and colorectal cancer risk. Clin Cancer Res 2014, 20:859-867.
7. Borresen A.L., Lothe R.A., Meling G.I., et al. Somatic mutations in the hMSH2 gene in microsatellite unstable colorectal carcinomas. Hum Mol Genet 1995, 4:2065-2072.
8. Buc E., Dubois D., Sauvanet P., et al. High prevalence of mucosa-associated E. coli producing cyclomodulin and genotoxin in colon cancer. PLoS ONE 2013, 8:e56964.
9. Charpentier X., Oswald E. Identification of the secretion and translocation domain of the enteropathogenic and enterohemorrhagic Escherichia coli effector Cif, using TEM-1 beta-lactamase as a new fluorescence-based reporter. J Bacteriol 2004, 186:5486-5495.
10. Chou K.C., Shen H.B. Cell-PLoc: a package of Web servers for predicting subcellular localization of proteins in various organisms. Nat Protoc 2008, 3:153-162.
11. Collins D., Hogan A.M., Winter D.C. Microbial and viral pathogens in colorectal cancer. Lancet Oncol 2011, 12:504-512.
12. Conterno L., Fava F., Viola R., Tuohy K.M. Obesity and the gut microbiota: does up-regulating colonic fermentation protect against obesity and metabolic disease?. Genes Nutr 2011, 6:241-260.
13. Cougnoux A., Dalmasso G., Martinez R., et al. Bacterial genotoxin colibactin promotes colon tumour growth by inducing a senescence-associated secretory phenotype. Gut 2014, 63:1932-1942.
14. de Martel C., Franceschi S. Infections and cancer: established associations and new hypotheses. Crit Rev Oncol Hematol 2009, 70:183-194.
15. Dunning Hotopp J.C., Clark M.E., Oliveira D.C., et al. Widespread lateral gene transfer from intracellular bacteria to multicellular eukaryotes. Science 2007, 317:1753-1756.
16. Edgar B.A., Orr-Weaver T.L. Endoreplication cell cycles: more for less. Cell 2001, 105:297-306.
17. Editorial Focus on host subversion. Nat Cell Biol 2009, 11:509.
18. Esteller M. Cancer epigenomics: DNA methylomes and histone-modification maps. Nat Rev Genet 2007, 8:286-298.
19. Fanaro S., Chierici R., Guerrini P., Vigi V. Intestinal microflora in early infancy: composition and development. Acta Paediatr Suppl 2003, 91:48-55.
20. Fiorentini C., Matarrese P., Straface E., et al. Toxin-induced activation of Rho GTP-binding protein increases Bcl-2 expression and influences mitochondrial homeostasis. Exp Cell Res 1998, 242:341-350.
21. Fishel R., Wilson T. MutS homologs in mammalian cells. Curr Opin Genet Dev 1997, 7:105-113.
22. Fishel R., Lescoe M.K., Rao M.R., et al. The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer. Cell 1993, 75:1027-1038.
23. Friswell M., Campbell B., Rhodes J. The role of bacteria in the pathogenesis of inflammatory bowel disease. Gut Liver 2010, 4:295-306.
24. Fukui K. DNA mismatch repair in eukaryotes and bacteria. J Nucleic Acids 2010, 2010:1-16.
25. Fukui K., Nishida M., Nakagawa N., Masui R., Kuramitsu S. Bound nucleotide controls the endonuclease activity of mismatch repair enzyme MutL. J Biol Chem 2008, 283:12136-12145.
26. Ge Z., Rogers A.B., Feng Y., et al. Bacterial cytolethal distending toxin promotes the development of dysplasia in a model of microbially induced hepatocarcinogenesis. Cell Microbiol 2007, 9:2070-2080.
27. Ge Z., Schauer D.B., Fox J.G. In vivo virulence properties of bacterial cytolethal-distending toxin. Cell Microbiol 2008, 10:1599-1607.
28. Gillen C.D., Andrews H.A., Prior P., Allan R.N. Crohn's disease and colorectal cancer. Gut 1994, 35:651-655.
29. Glasser A.L., Boudeau J., Barnich N., Perruchot M.H., Colombel J.F., Darfeuille-Michaud A. Adherent invasive Escherichia coli strains from patients with Crohn's disease survive and replicate within macrophages without inducing host cell death. Infect Immun 2001, 69:5529-5537.
30. Gronbaek K., Hother C., Jones P.A. Epigenetic changes in cancer. Apmis 2007, 115:1039-1059.
31. Haghjoo E., Galan J.E. Salmonella typhi encodes a functional cytolethal distending toxin that is delivered into host cells by a bacterial-internalization pathway. Proc Natl Acad Sci USA 2004, 101:4614-4619.
32. Jenkins M.A., Croitoru M.E., Monga N., et al. Risk of colorectal cancer in monoallelic and biallelic carriers of MYH mutations: a population-based case-family study. Cancer Epidemiol Biomarkers Prev 2006, 15:312-314.
33. Kaczmarczyk S.J., Sitaraman K., Hill T., Hartley J.L., Chatterjee D.K. Tus, an E. coli protein, contains mammalian nuclear targeting and exporting signals. PLoS ONE 2010, 5:e8889.
34. Kadyrov F.A., Dzantiev L., Constantin N., Modrich P. Endonucleolytic function of MutLalpha in human mismatch repair. Cell 2006, 126:297-308.
35. Kadyrov F.A., Holmes S.F., Arana M.E., et al. Saccharomyces cerevisiae MutLalpha is a mismatch repair endonuclease. J Biol Chem 2007, 282:37181-37190.
36. Kosugi S., Hasebe M., Tomita M., Yanagawa H. Systematic identification of cell cycle-dependent yeast nucleocytoplasmic shuttling proteins by prediction of composite motifs. Proc Natl Acad Sci USA 2009, 106:10171-10176.
37. Lara-Tejero M., Galan J.E. CdtA, CdtB, and CdtC form a tripartite complex that is required for cytolethal distending toxin activity. Infect Immun 2001, 69:4358-4365.
38. Lee J.C., Kim D.S., Moon D.C., Lee J.H., Kim M.J., Lee S.M., et al. Prediction of bacterial proteins carrying a nuclear localization signal and nuclear targeting of HsdM from Klebsiella pneumoniae. J Microbiol 2009, 47:641-645.
39. Lu H., Ouyang W., Huang C. Inflammation, a key event in cancer development. Mol Cancer Res 2006, 4:221-233.
40. Lynch H.T., Smyrk T.C., Watson P., et al. Genetics, natural history, tumor spectrum, and pathology of hereditary nonpolyposis colorectal cancer: an updated review. Gastroenterology 1993, 104:1535-1549.
41. Maddocks O.D., Short A.J., Donnenberg M.S., Bader S., Harrison D.J. Attaching and effacing Escherichia coli downregulate DNA mismatch repair protein in vitro and are associated with colorectal adenocarcinomas in humans. PLoS ONE 2009, 4:e5517.
42. Maddocks O.D., Scanlon K.M., Donnenberg M.S. An Escherichia coli effector protein promotes host mutation via depletion of DNA mismatch repair proteins. MBio 2013, 4:e00152-e213.
43. Mager D.L. Bacteria and cancer: cause, coincidence or cure? A review. J Transl Med 2006, 4:14.
44. Marches O., Ledger T.N., Boury M., et al. Enteropathogenic and enterohaemorrhagic Escherichia coli deliver a novel effector called Cif, which blocks cell cycle G2/M transition. Mol Microbiol 2003, 50:1553-1567.
45. Markowitz S.D., Bertagnolli M.M. Molecular origins of cancer: molecular basis of colorectal cancer. N Engl J Med 2009, 361:2449-2460.
46. Martinez-Medina M., Garcia-Gil L.J. Escherichia coli in chronic inflammatory bowel diseases: an update on adherent invasive Escherichia coli pathogenicity. World J Gastrointest Pathophysiol 2014, 5:213-227.
47. Martin H.M., Campbell B.J., Hart C.A., et al. Enhanced Escherichia coli adherence and invasion in Crohn's disease and colon cancer. Gastroenterology 2004, 127:80-93.
48. Masotti A. Interplays between gut microbiota and gene expression regulation by miRNAs. Front Cell Infect Microbiol 2012, 2:137.
49. Masseret E., Boudeau J., Colombel J.F., et al. Genetically related Escherichia coli strains associated with Crohn's disease. Gut 2001, 48:320-325.
50. Mauris J., Evans T.C. Adenosine triphosphate stimulates Aquifex aeolicus MutL endonuclease activity. PLoS ONE 2009, 4:e7175.
51. Mauris J., Evans T.C. A human PMS2 homologue from Aquifex aeolicus stimulates an ATP-dependent DNA helicase. J Biol Chem 2010, 285:11087-11092.
52. Meijer K., de Vos P., Priebe M.G. Butyrate and other short-chain fatty acids as modulators of immunity: what relevance for health?. Curr Opin Clin Nutr Metab Care 2010, 13:715-721.
53. Minarovits J. Microbe-induced epigenetic alterations in host cells: the coming era of patho-epigenetics of microbial infections. A review. Acta Microbiol Immunol Hung 2009, 56:1-19.
54. Molloy S. New tricks for E. coli?. Nat Rev Microbiol 2006, 4:722-723.
55. Muller A., Fishel R. Mismatch repair and the hereditary non-polyposis colorectal cancer syndrome (HNPCC). Cancer Invest 2002, 20:102-109.
56. Neish A.S. Microbes in gastrointestinal health and disease. Gastroenterology 2009, 136:65-80.
57. Nougayrede J.P., Taieb F., De Rycke J., Oswald E. Cyclomodulins: bacterial effectors that modulate the eukaryotic cell cycle. Trends Microbiol 2005, 13:103-110.
58. Oswald E., Sugai M., Labigne A., et al. Cytotoxic necrotizing factor type 2 produced by virulent Escherichia coli modifies the small GTP-binding proteins Rho involved in assembly of actin stress fibers. Proc Natl Acad Sci USA 1994, 91:3814-3818.
59. Parkin D.M., Bray F., Ferlay J., Pisani P. Global cancer statistics, 2002. Cancer J Clin 2005, 55:74-108.
60. Paschos K., Allday M.J. Epigenetic reprogramming of host genes in viral and microbial pathogenesis. Trends Microbiol 2010, 18:439-447.
61. Peterlongo P., Mitra N., Chuai S., et al. Colorectal cancer risk in individuals with biallelic or monoallelic mutations of MYH. Int J Cancer 2005, 114:505-507.
62. Pierleoni A., Martelli P.L., Fariselli P., Casadio R. BaCelLo: a balanced subcellular localization predictor. Bioinformatics 2006, 22:e408-e416.
63. Prolla T.A., Abuin A., Bradley A. DNA mismatch repair deficient mice in cancer research. Semin Cancer Biol 1996, 7:241-247.
64. Raisch J., Buc E., Bonnet M., et al. Colon cancer-associated B2 Escherichia coli colonize gut mucosa and promote cell proliferation. World J Gastroenterol 2014, 20:6560-6572.
65. Rolhion N., Darfeuille-Michaud A. Adherent-invasive Escherichia coli in inflammatory bowel disease. Inflamm Bowel Dis 2007, 13:1277-1283.
66. Rolhion N., Carvalho F.A., Darfeuille-Michaud A. OmpC and the sigma(E) regulatory pathway are involved in adhesion and invasion of the Crohn's disease-associated Escherichia coli strain LF82. Mol Microbiol 2007, 63:1684-1700.
67. Sassen S., Miska E.A., Caldas C. MicroRNA: implications for cancer. Virchows Arch 2008, 452:1-10.
68. Schwabe R.F., Jobin C. The microbiome and cancer. Nat Rev Cancer 2012, 13:800-812.
69. Schwabe R.F., Jobin C. The microbiome and cancer. Nat Rev Cancer 2013, 13:800-812.
70. Schwabe R.F., Wang T.C. Cancer. Bacteria deliver a genotoxic hit. Science 2012, 338:52-53.
71. Shahanavaj K., Gil-Bazo I., Castiglia M., et al. Cancer and the microbiome: potential applications as new tumor biomarker. Expert Rev Anticancer Ther 2015, 15:317-330.
72. Slupska M.M., Baikalov C., Luther W.M., Chiang J.H., Wei Y.F., Miller J.H. Cloning and sequencing a human homolog (hMYH) of the Escherichia coli mutY gene whose function is required for the repair of oxidative DNA damage. J Bacteriol 1996, 178:3885-3892.
73. Swidsinski A., Khilkin M., Kerjaschki D., et al. Association between intraepithelial Escherichia coli and colorectal cancer. Gastroenterology 1998, 115:281-286.
74. Taieb F., Nougayrede J.P., Watrin C., Samba-Louaka A., Oswald E. Escherichia coli cyclomodulin Cif induces G2 arrest of the host cell cycle without activation of the DNA-damage checkpoint-signalling pathway. Cell Microbiol 2006, 8:1910-1921.
75. Tili E., Michaille J.J., Cimino A., et al. Modulation of miR-155 and miR-125b levels following lipopolysaccharide/TNF-alpha stimulation and their possible roles in regulating the response to endotoxin shock. J Immunol 2007, 179:5082-5089.
76. Tjalsma H., Boleij A., Marchesi J.R., Dutilh B.E. A bacterial driver-passenger model for colorectal cancer: beyond the usual suspects. Nat Rev Microbiol 2012, 10:575-582.
77. Toth I., Herault F., Beutin L., Oswald E. Production of cytolethal distending toxins by pathogenic Escherichia coli strains isolated from human and animal sources: establishment of the existence of a new cdt variant (Type IV). J Clin Microbiol 2003, 41:4285-4291.
78. Touchon M., Hoede C., Tenaillon O., et al. Organised genome dynamics in the Escherichia coli species results in highly diverse adaptive paths. PLoS Genet 2009, 5:e1000344.
79. Vajro P., Paolella G., Fasano A. Microbiota gut-liver axis: their influences on obesity and obesity-related liver disease. J Pediatr Gastroenterol Nutr 2013, 56:461-468.
80. Wheeler L.A., Soderberg F.B., Goldman P. The reduction of N-hydroxy-4-acetylaminobiphenyl by the intestinal microflora of the rat. Cancer Res 1975, 35:2962-2968.
81. Wogan G.N., Dedon P.C., Tannenbaum S.R., Fox J.G. Infection, inflammation and colon carcinogenesis. Oncotarget 2012, 3:737-738.
82. Zitt M., Muller H.M. DNA methylation in colorectal cancer-impact on screening and therapy monitoring modalities?. Dis Markers 2007, 23:51-71.