메뉴 건너뛰기




Volumn 17, Issue 2, 2019, Pages 322-332

The Gut–Brain Axis and the Microbiome: Mechanisms and Clinical Implications

Author keywords

Diet; Early Life Influences; Irritable Bowel Syndrome

Indexed keywords

PROBIOTIC AGENT; BIOLOGICAL FACTOR;

EID: 85059157933     PISSN: 15423565     EISSN: 15427714     Source Type: Journal    
DOI: 10.1016/j.cgh.2018.10.002     Document Type: Review
Times cited : (341)

References (135)
  • 1
    • 84856509724 scopus 로고    scopus 로고
    • Short-chain fatty acids stimulate glucagon-like peptide-1 secretion via the G-protein-coupled receptor FFAR2
    • Tolhurst, G., Heffron, H., Lam, Y.S., et al. Short-chain fatty acids stimulate glucagon-like peptide-1 secretion via the G-protein-coupled receptor FFAR2. Diabetes 61 (2012), 364–371.
    • (2012) Diabetes , vol.61 , pp. 364-371
    • Tolhurst, G.1    Heffron, H.2    Lam, Y.S.3
  • 2
    • 62649151803 scopus 로고    scopus 로고
    • Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites
    • Wikoff, W.R., Anfora, A.T., Liu, J., et al. Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites. Proc Natl Acad Sci U S A 106 (2009), 3698–3703.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 3698-3703
    • Wikoff, W.R.1    Anfora, A.T.2    Liu, J.3
  • 3
    • 84927131694 scopus 로고    scopus 로고
    • Indigenous bacteria from the gut microbiota regulate host serotonin biosynthesis
    • Yano, J.M., Yu, K., Donaldson, G.P., et al. Indigenous bacteria from the gut microbiota regulate host serotonin biosynthesis. Cell 161 (2015), 264–276.
    • (2015) Cell , vol.161 , pp. 264-276
    • Yano, J.M.1    Yu, K.2    Donaldson, G.P.3
  • 4
    • 55949091259 scopus 로고    scopus 로고
    • Effects of the gut microbiota on host adiposity are modulated by the short-chain fatty-acid binding G protein-coupled receptor, Gpr41
    • Samuel, B.S., Shaito, A., Motoike, T., et al. Effects of the gut microbiota on host adiposity are modulated by the short-chain fatty-acid binding G protein-coupled receptor, Gpr41. Proc Natl Acad Sci U S A 105 (2008), 16767–16772.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 16767-16772
    • Samuel, B.S.1    Shaito, A.2    Motoike, T.3
  • 5
    • 84944682179 scopus 로고    scopus 로고
    • Dietary fatty acids directly impact central nervous system autoimmunity via the small intestine
    • Haghikia, A., Jorg, S., Duscha, A., et al. Dietary fatty acids directly impact central nervous system autoimmunity via the small intestine. Immunity 43 (2015), 817–829.
    • (2015) Immunity , vol.43 , pp. 817-829
    • Haghikia, A.1    Jorg, S.2    Duscha, A.3
  • 6
    • 80052965474 scopus 로고    scopus 로고
    • Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve
    • Bravo, J.A., Forsythe, P., Chew, M.V., et al. Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve. Proc Natl Acad Sci U S A 108 (2011), 16050–16055.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 16050-16055
    • Bravo, J.A.1    Forsythe, P.2    Chew, M.V.3
  • 7
    • 20444374493 scopus 로고    scopus 로고
    • Activation in vagal afferents and central autonomic pathways: early responses to intestinal infection with Campylobacter jejuni
    • Goehler, L.E., Gaykema, R.P., Opitz, N., et al. Activation in vagal afferents and central autonomic pathways: early responses to intestinal infection with Campylobacter jejuni. Brain Behav Immun 19 (2005), 334–344.
    • (2005) Brain Behav Immun , vol.19 , pp. 334-344
    • Goehler, L.E.1    Gaykema, R.P.2    Opitz, N.3
  • 8
    • 84893411706 scopus 로고    scopus 로고
    • Central action of FGF19 reduces hypothalamic AGRP/NPY neuron activity and improves glucose metabolism
    • Marcelin, G., Jo, Y.H., Li, X., et al. Central action of FGF19 reduces hypothalamic AGRP/NPY neuron activity and improves glucose metabolism. Mol Metab 3 (2014), 19–28.
    • (2014) Mol Metab , vol.3 , pp. 19-28
    • Marcelin, G.1    Jo, Y.H.2    Li, X.3
  • 9
    • 84871694003 scopus 로고    scopus 로고
    • Fibroblast growth factor-19 action in the brain reduces food intake and body weight and improves glucose tolerance in male rats
    • Ryan, K.K., Kohli, R., Gutierrez-Aguilar, R., et al. Fibroblast growth factor-19 action in the brain reduces food intake and body weight and improves glucose tolerance in male rats. Endocrinology 154 (2013), 9–15.
    • (2013) Endocrinology , vol.154 , pp. 9-15
    • Ryan, K.K.1    Kohli, R.2    Gutierrez-Aguilar, R.3
  • 10
    • 84928790920 scopus 로고    scopus 로고
    • FGF1 and FGF19 reverse diabetes by suppression of the hypothalamic-pituitary-adrenal axis
    • Perry, R.J., Lee, S., Ma, L., et al. FGF1 and FGF19 reverse diabetes by suppression of the hypothalamic-pituitary-adrenal axis. Nat Commun, 6, 2015, 6980.
    • (2015) Nat Commun , vol.6 , pp. 6980
    • Perry, R.J.1    Lee, S.2    Ma, L.3
  • 11
    • 84949117481 scopus 로고    scopus 로고
    • Release of GLP-1 and PYY in response to the activation of G protein-coupled bile acid receptor TGR5 is mediated by Epac/PLC-epsilon pathway and modulated by endogenous H2S
    • Bala, V., Rajagopal, S., Kumar, D.P., et al. Release of GLP-1 and PYY in response to the activation of G protein-coupled bile acid receptor TGR5 is mediated by Epac/PLC-epsilon pathway and modulated by endogenous H2S. Front Physiol, 5, 2014, 420.
    • (2014) Front Physiol , vol.5 , pp. 420
    • Bala, V.1    Rajagopal, S.2    Kumar, D.P.3
  • 12
    • 70350662669 scopus 로고    scopus 로고
    • Gut microbiota fermentation of prebiotics increases satietogenic and incretin gut peptide production with consequences for appetite sensation and glucose response after a meal
    • Cani, P.D., Lecourt, E., Dewulf, E.M., et al. Gut microbiota fermentation of prebiotics increases satietogenic and incretin gut peptide production with consequences for appetite sensation and glucose response after a meal. Am J Clin Nutr 90 (2009), 1236–1243.
    • (2009) Am J Clin Nutr , vol.90 , pp. 1236-1243
    • Cani, P.D.1    Lecourt, E.2    Dewulf, E.M.3
  • 13
    • 0742305675 scopus 로고    scopus 로고
    • Short-chain fatty acids stimulate leptin production in adipocytes through the G protein-coupled receptor GPR41
    • Xiong, Y., Miyamoto, N., Shibata, K., et al. Short-chain fatty acids stimulate leptin production in adipocytes through the G protein-coupled receptor GPR41. Proc Natl Acad Sci U S A 101 (2004), 1045–1050.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 1045-1050
    • Xiong, Y.1    Miyamoto, N.2    Shibata, K.3
  • 14
    • 84912137874 scopus 로고    scopus 로고
    • Bacterial metabolite indole modulates incretin secretion from intestinal enteroendocrine L cells
    • Chimerel, C., Emery, E., Summers, D.K., et al. Bacterial metabolite indole modulates incretin secretion from intestinal enteroendocrine L cells. Cell Rep 9 (2014), 1202–1208.
    • (2014) Cell Rep , vol.9 , pp. 1202-1208
    • Chimerel, C.1    Emery, E.2    Summers, D.K.3
  • 15
    • 50949098849 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor signaling mediates expression of indoleamine 2,3-dioxygenase
    • Vogel, C.F., Goth, S.R., Dong, B., et al. Aryl hydrocarbon receptor signaling mediates expression of indoleamine 2,3-dioxygenase. Biochem Biophys Res Commun 375 (2008), 331–335.
    • (2008) Biochem Biophys Res Commun , vol.375 , pp. 331-335
    • Vogel, C.F.1    Goth, S.R.2    Dong, B.3
  • 16
    • 33947667036 scopus 로고    scopus 로고
    • Activation of enteroendocrine cells via TLRs induces hormone, chemokine, and defensin secretion
    • Palazzo, M., Balsari, A., Rossini, A., et al. Activation of enteroendocrine cells via TLRs induces hormone, chemokine, and defensin secretion. J Immunol 178 (2007), 4296–4303.
    • (2007) J Immunol , vol.178 , pp. 4296-4303
    • Palazzo, M.1    Balsari, A.2    Rossini, A.3
  • 17
    • 84982994263 scopus 로고    scopus 로고
    • TLR ligands and butyrate increase Pyy expression through two distinct but inter-regulated pathways
    • Larraufie, P., Dore, J., Lapaque, N., et al. TLR ligands and butyrate increase Pyy expression through two distinct but inter-regulated pathways. Cell Microbiol, 19, 2017.
    • (2017) Cell Microbiol , vol.19
    • Larraufie, P.1    Dore, J.2    Lapaque, N.3
  • 18
    • 62449290353 scopus 로고    scopus 로고
    • IL1beta- and LPS-induced serotonin secretion is increased in EC cells derived from Crohn's disease
    • Kidd, M., Gustafsson, B.I., Drozdov, I., et al. IL1beta- and LPS-induced serotonin secretion is increased in EC cells derived from Crohn's disease. Neurogastroenterol Motil 21 (2009), 439–450.
    • (2009) Neurogastroenterol Motil , vol.21 , pp. 439-450
    • Kidd, M.1    Gustafsson, B.I.2    Drozdov, I.3
  • 19
    • 84866546211 scopus 로고    scopus 로고
    • Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour
    • Cryan, J.F., Dinan, T.G., Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour. Nat Rev Neurosci 13 (2012), 701–712.
    • (2012) Nat Rev Neurosci , vol.13 , pp. 701-712
    • Cryan, J.F.1    Dinan, T.G.2
  • 20
    • 84929310699 scopus 로고    scopus 로고
    • Control of brain development, function, and behavior by the microbiome
    • Sampson, T.R., Mazmanian, S.K., Control of brain development, function, and behavior by the microbiome. Cell Host Microbe 17 (2015), 565–576.
    • (2015) Cell Host Microbe , vol.17 , pp. 565-576
    • Sampson, T.R.1    Mazmanian, S.K.2
  • 22
    • 84878478721 scopus 로고    scopus 로고
    • In vivo dynamics of innate immune sentinels in the CNS
    • Nayak, D., Zinselmeyer, B.H., Corps, K.N., et al. In vivo dynamics of innate immune sentinels in the CNS. Intravital 1 (2012), 95–106.
    • (2012) Intravital , vol.1 , pp. 95-106
    • Nayak, D.1    Zinselmeyer, B.H.2    Corps, K.N.3
  • 23
    • 84933043202 scopus 로고    scopus 로고
    • Host microbiota constantly control maturation and function of microglia in the CNS
    • Erny, D., Hrabe de Angelis, A.L., Jaitin, D., et al. Host microbiota constantly control maturation and function of microglia in the CNS. Nat Neurosci 18 (2015), 965–977.
    • (2015) Nat Neurosci , vol.18 , pp. 965-977
    • Erny, D.1    Hrabe de Angelis, A.L.2    Jaitin, D.3
  • 24
    • 84881068658 scopus 로고    scopus 로고
    • The microbial metabolites, short-chain fatty acids, regulate colonic Treg cell homeostasis
    • Smith, P.M., Howitt, M.R., Panikov, N., et al. The microbial metabolites, short-chain fatty acids, regulate colonic Treg cell homeostasis. Science 341 (2013), 569–573.
    • (2013) Science , vol.341 , pp. 569-573
    • Smith, P.M.1    Howitt, M.R.2    Panikov, N.3
  • 25
    • 84976883162 scopus 로고    scopus 로고
    • Microglia development follows a stepwise program to regulate brain homeostasis
    • aad8670
    • Matcovitch-Natan, O., Winter, D.R., Giladi, A., et al. Microglia development follows a stepwise program to regulate brain homeostasis. Science, 353, 2016 aad8670.
    • (2016) Science , vol.353
    • Matcovitch-Natan, O.1    Winter, D.R.2    Giladi, A.3
  • 26
    • 84933055405 scopus 로고    scopus 로고
    • Diversity of astrocyte functions and phenotypes in neural circuits
    • Khakh, B.S., Sofroniew, M.V., Diversity of astrocyte functions and phenotypes in neural circuits. Nat Neurosci 18 (2015), 942–952.
    • (2015) Nat Neurosci , vol.18 , pp. 942-952
    • Khakh, B.S.1    Sofroniew, M.V.2
  • 27
    • 84966658995 scopus 로고    scopus 로고
    • Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor
    • Rothhammer, V., Mascanfroni, I.D., Bunse, L., et al. Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor. Nat Med 22 (2016), 586–597.
    • (2016) Nat Med , vol.22 , pp. 586-597
    • Rothhammer, V.1    Mascanfroni, I.D.2    Bunse, L.3
  • 28
    • 84938675563 scopus 로고    scopus 로고
    • Adaptation of the human aryl hydrocarbon receptor to sense microbiota-derived indoles
    • Hubbard, T.D., Murray, I.A., Bisson, W.H., et al. Adaptation of the human aryl hydrocarbon receptor to sense microbiota-derived indoles. Sci Rep, 5, 2015, 12689.
    • (2015) Sci Rep , vol.5 , pp. 12689
    • Hubbard, T.D.1    Murray, I.A.2    Bisson, W.H.3
  • 30
    • 84996928524 scopus 로고    scopus 로고
    • Kynurenine pathway metabolism and the microbiota-gut-brain axis
    • Kennedy, P.J., Cryan, J.F., Dinan, T.G., et al. Kynurenine pathway metabolism and the microbiota-gut-brain axis. Neuropharmacology 112 (2017), 399–412.
    • (2017) Neuropharmacology , vol.112 , pp. 399-412
    • Kennedy, P.J.1    Cryan, J.F.2    Dinan, T.G.3
  • 31
    • 84897374287 scopus 로고    scopus 로고
    • Microbiome-derived tryptophan metabolites and their aryl hydrocarbon receptor-dependent agonist and antagonist activities
    • Jin, U.H., Lee, S.O., Sridharan, G., et al. Microbiome-derived tryptophan metabolites and their aryl hydrocarbon receptor-dependent agonist and antagonist activities. Mol Pharmacol 85 (2014), 777–788.
    • (2014) Mol Pharmacol , vol.85 , pp. 777-788
    • Jin, U.H.1    Lee, S.O.2    Sridharan, G.3
  • 32
    • 84969531690 scopus 로고    scopus 로고
    • Skatole (3-methylindole) is a partial aryl hydrocarbon receptor agonist and induces CYP1A1/2 and CYP1B1 expression in primary human hepatocytes
    • Rasmussen, M.K., Balaguer, P., Ekstrand, B., et al. Skatole (3-methylindole) is a partial aryl hydrocarbon receptor agonist and induces CYP1A1/2 and CYP1B1 expression in primary human hepatocytes. PLoS One, 11, 2016, e0154629.
    • (2016) PLoS One , vol.11 , pp. e0154629
    • Rasmussen, M.K.1    Balaguer, P.2    Ekstrand, B.3
  • 33
    • 84944446673 scopus 로고    scopus 로고
    • Breaking down the barriers: the gut microbiome, intestinal permeability and stress-related psychiatric disorders
    • Kelly, J.R., Kennedy, P.J., Cryan, J.F., et al. Breaking down the barriers: the gut microbiome, intestinal permeability and stress-related psychiatric disorders. Front Cell Neurosci, 9, 2015, 392.
    • (2015) Front Cell Neurosci , vol.9 , pp. 392
    • Kelly, J.R.1    Kennedy, P.J.2    Cryan, J.F.3
  • 34
    • 84911884131 scopus 로고    scopus 로고
    • The gut microbiota influences blood-brain barrier permeability in mice
    • 263ra158
    • Braniste, V., Al-Asmakh, M., Kowal, C., et al. The gut microbiota influences blood-brain barrier permeability in mice. Sci Transl Med, 6, 2014 263ra158.
    • (2014) Sci Transl Med , vol.6
    • Braniste, V.1    Al-Asmakh, M.2    Kowal, C.3
  • 35
    • 70350343544 scopus 로고    scopus 로고
    • Induction of intestinal Th17 cells by segmented filamentous bacteria
    • Ivanov, I.I., Atarashi, K., Manel, N., et al. Induction of intestinal Th17 cells by segmented filamentous bacteria. Cell 139 (2009), 485–498.
    • (2009) Cell , vol.139 , pp. 485-498
    • Ivanov, I.I.1    Atarashi, K.2    Manel, N.3
  • 36
    • 79956311926 scopus 로고    scopus 로고
    • The Toll-like receptor 2 pathway establishes colonization by a commensal of the human microbiota
    • Round, J.L., Lee, S.M., Li, J., et al. The Toll-like receptor 2 pathway establishes colonization by a commensal of the human microbiota. Science 332 (2011), 974–977.
    • (2011) Science , vol.332 , pp. 974-977
    • Round, J.L.1    Lee, S.M.2    Li, J.3
  • 37
    • 84898777631 scopus 로고    scopus 로고
    • Brain-gut microbiome interactions and functional bowel disorders
    • Mayer, E.A., Savidge, T., Shulman, R.J., Brain-gut microbiome interactions and functional bowel disorders. Gastroenterology 146 (2014), 1500–1512.
    • (2014) Gastroenterology , vol.146 , pp. 1500-1512
    • Mayer, E.A.1    Savidge, T.2    Shulman, R.J.3
  • 38
    • 34247354093 scopus 로고    scopus 로고
    • Microbial biofilms in the human gastrointestinal tract
    • Macfarlane, S., Dillon, J.F., Microbial biofilms in the human gastrointestinal tract. J Appl Microbiol 102 (2007), 1187–1196.
    • (2007) J Appl Microbiol , vol.102 , pp. 1187-1196
    • Macfarlane, S.1    Dillon, J.F.2
  • 39
    • 84995739780 scopus 로고    scopus 로고
    • A dietary fiber-deprived gut microbiota degrades the colonic mucus barrier and enhances pathogen susceptibility
    • Desai, M.S., Seekatz, A.M., Koropatkin, N.M., et al. A dietary fiber-deprived gut microbiota degrades the colonic mucus barrier and enhances pathogen susceptibility. Cell 167 (2016), 1339–1353 e21.
    • (2016) Cell , vol.167 , pp. 1339-1353 e21
    • Desai, M.S.1    Seekatz, A.M.2    Koropatkin, N.M.3
  • 40
    • 33947631511 scopus 로고    scopus 로고
    • IL-1beta causes an increase in intestinal epithelial tight junction permeability
    • Al-Sadi, R.M., Ma, T.Y., IL-1beta causes an increase in intestinal epithelial tight junction permeability. J Immunol 178 (2007), 4641–4649.
    • (2007) J Immunol , vol.178 , pp. 4641-4649
    • Al-Sadi, R.M.1    Ma, T.Y.2
  • 41
    • 0032878564 scopus 로고    scopus 로고
    • Corticotropin-releasing hormone mimics stress-induced colonic epithelial pathophysiology in the rat
    • Santos, J., Saunders, P.R., Hanssen, N.P., et al. Corticotropin-releasing hormone mimics stress-induced colonic epithelial pathophysiology in the rat. Am J Physiol 277 (1999), G391–G399.
    • (1999) Am J Physiol , vol.277 , pp. G391-G399
    • Santos, J.1    Saunders, P.R.2    Hanssen, N.P.3
  • 42
    • 0038363378 scopus 로고    scopus 로고
    • The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids
    • Brown, A.J., Goldsworthy, S.M., Barnes, A.A., et al. The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids. J Biol Chem 278 (2003), 11312–11319.
    • (2003) J Biol Chem , vol.278 , pp. 11312-11319
    • Brown, A.J.1    Goldsworthy, S.M.2    Barnes, A.A.3
  • 43
    • 0015806556 scopus 로고
    • Multiday exposure of men to high nitrogen pressure and increased airway resistance at natural expired oxygen tension: a 14-day continuous exposure to 5.2 per cent O 2 in N 2 at 4.0 atmospheres absolute pressure
    • Lambertsen, C.J., Wright, W.B., Multiday exposure of men to high nitrogen pressure and increased airway resistance at natural expired oxygen tension: a 14-day continuous exposure to 5.2 per cent O 2 in N 2 at 4.0 atmospheres absolute pressure. Aerosp Med 44 (1973), 826–827.
    • (1973) Aerosp Med , vol.44 , pp. 826-827
    • Lambertsen, C.J.1    Wright, W.B.2
  • 44
    • 84961282418 scopus 로고    scopus 로고
    • The blood-brain barrier in systemic inflammation
    • Varatharaj, A., Galea, I., The blood-brain barrier in systemic inflammation. Brain Behav Immun 60 (2017), 1–12.
    • (2017) Brain Behav Immun , vol.60 , pp. 1-12
    • Varatharaj, A.1    Galea, I.2
  • 45
    • 79960645242 scopus 로고    scopus 로고
    • Gut feelings: the emerging biology of gut-brain communication
    • Mayer, E.A., Gut feelings: the emerging biology of gut-brain communication. Nat Rev Neurosci 12 (2011), 453–466.
    • (2011) Nat Rev Neurosci , vol.12 , pp. 453-466
    • Mayer, E.A.1
  • 46
    • 84880131833 scopus 로고    scopus 로고
    • Stress and antibiotics alter luminal and wall-adhered microbiota and enhance the local expression of visceral sensory-related systems in mice
    • Aguilera, M., Vergara, P., Martinez, V., Stress and antibiotics alter luminal and wall-adhered microbiota and enhance the local expression of visceral sensory-related systems in mice. Neurogastroenterol Motil 25 (2013), e515–e529.
    • (2013) Neurogastroenterol Motil , vol.25 , pp. e515-e529
    • Aguilera, M.1    Vergara, P.2    Martinez, V.3
  • 47
    • 0015991231 scopus 로고
    • Influences of dietary and environmental stress on microbial populations in the murine gastrointestinal tract
    • Tannock, G.W., Savage, D.C., Influences of dietary and environmental stress on microbial populations in the murine gastrointestinal tract. Infect Immun 9 (1974), 591–598.
    • (1974) Infect Immun , vol.9 , pp. 591-598
    • Tannock, G.W.1    Savage, D.C.2
  • 48
    • 0038095630 scopus 로고    scopus 로고
    • Interdigestive small bowel motility and duodenal bacterial overgrowth in experimental acute pancreatitis
    • Van Felius, I.D., Akkermans, L.M., Bosscha, K., et al. Interdigestive small bowel motility and duodenal bacterial overgrowth in experimental acute pancreatitis. Neurogastroenterol Motil 15 (2003), 267–276.
    • (2003) Neurogastroenterol Motil , vol.15 , pp. 267-276
    • Van Felius, I.D.1    Akkermans, L.M.2    Bosscha, K.3
  • 49
    • 84952942226 scopus 로고    scopus 로고
    • Stool consistency is strongly associated with gut microbiota richness and composition, enterotypes and bacterial growth rates
    • Vandeputte, D., Falony, G., Vieira-Silva, S., et al. Stool consistency is strongly associated with gut microbiota richness and composition, enterotypes and bacterial growth rates. Gut 65 (2016), 57–62.
    • (2016) Gut , vol.65 , pp. 57-62
    • Vandeputte, D.1    Falony, G.2    Vieira-Silva, S.3
  • 50
    • 84963699544 scopus 로고    scopus 로고
    • Brain injury induces specific changes in the caecal microbiota of mice via altered autonomic activity and mucoprotein production
    • Houlden, A., Goldrick, M., Brough, D., et al. Brain injury induces specific changes in the caecal microbiota of mice via altered autonomic activity and mucoprotein production. Brain Behav Immun 57 (2016), 10–20.
    • (2016) Brain Behav Immun , vol.57 , pp. 10-20
    • Houlden, A.1    Goldrick, M.2    Brough, D.3
  • 51
    • 84975145731 scopus 로고    scopus 로고
    • Fetal, neonatal, and infant microbiome: perturbations and subsequent effects on brain development and behavior
    • Diaz Heijtz, R., Fetal, neonatal, and infant microbiome: perturbations and subsequent effects on brain development and behavior. Semin Fetal Neonatal Med 21 (2016), 410–417.
    • (2016) Semin Fetal Neonatal Med , vol.21 , pp. 410-417
    • Diaz Heijtz, R.1
  • 52
    • 84947461438 scopus 로고    scopus 로고
    • Feeding the brain and nurturing the mind: linking nutrition and the gut microbiota to brain development
    • Goyal, M.S., Venkatesh, S., Milbrandt, J., et al. Feeding the brain and nurturing the mind: linking nutrition and the gut microbiota to brain development. Proc Natl Acad Sci U S A 112 (2015), 14105–14112.
    • (2015) Proc Natl Acad Sci U S A , vol.112 , pp. 14105-14112
    • Goyal, M.S.1    Venkatesh, S.2    Milbrandt, J.3
  • 53
    • 77955386857 scopus 로고    scopus 로고
    • Delivery mode shapes the acquisition and structure of the initial microbiota across multiple body habitats in newborns
    • Dominguez-Bello, M.G., Costello, E.K., Contreras, M., et al. Delivery mode shapes the acquisition and structure of the initial microbiota across multiple body habitats in newborns. Proc Natl Acad Sci U S A 107 (2010), 11971–11975.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 11971-11975
    • Dominguez-Bello, M.G.1    Costello, E.K.2    Contreras, M.3
  • 54
    • 84942739564 scopus 로고    scopus 로고
    • Alterations in the vaginal microbiome by maternal stress are associated with metabolic reprogramming of the offspring gut and brain
    • Jasarevic, E., Howerton, C.L., Howard, C.D., et al. Alterations in the vaginal microbiome by maternal stress are associated with metabolic reprogramming of the offspring gut and brain. Endocrinology 156 (2015), 3265–3276.
    • (2015) Endocrinology , vol.156 , pp. 3265-3276
    • Jasarevic, E.1    Howerton, C.L.2    Howard, C.D.3
  • 55
    • 52749096519 scopus 로고    scopus 로고
    • Acute maternal stress in pregnancy and schizophrenia in offspring: a cohort prospective study
    • Malaspina, D., Corcoran, C., Kleinhaus, K.R., et al. Acute maternal stress in pregnancy and schizophrenia in offspring: a cohort prospective study. BMC Psychiatry, 8, 2008, 71.
    • (2008) BMC Psychiatry , vol.8 , pp. 71
    • Malaspina, D.1    Corcoran, C.2    Kleinhaus, K.R.3
  • 56
    • 81555197565 scopus 로고    scopus 로고
    • Prenatal maternal stress associated with ADHD and autistic traits in early childhood
    • Ronald, A., Pennell, C.E., Whitehouse, A.J., Prenatal maternal stress associated with ADHD and autistic traits in early childhood. Front Psychol, 1, 2010, 223.
    • (2010) Front Psychol , vol.1 , pp. 223
    • Ronald, A.1    Pennell, C.E.2    Whitehouse, A.J.3
  • 57
    • 84978619185 scopus 로고    scopus 로고
    • Partial restoration of the microbiota of cesarean-born infants via vaginal microbial transfer
    • Dominguez-Bello, M.G., De Jesus-Laboy, K.M., Shen, N., et al. Partial restoration of the microbiota of cesarean-born infants via vaginal microbial transfer. Nat Med 22 (2016), 250–253.
    • (2016) Nat Med , vol.22 , pp. 250-253
    • Dominguez-Bello, M.G.1    De Jesus-Laboy, K.M.2    Shen, N.3
  • 58
    • 84929297936 scopus 로고    scopus 로고
    • Dynamics and stabilization of the human gut microbiome during the first year of life
    • Backhed, F., Roswall, J., Peng, Y., et al. Dynamics and stabilization of the human gut microbiome during the first year of life. Cell Host Microbe 17 (2015), 690–703.
    • (2015) Cell Host Microbe , vol.17 , pp. 690-703
    • Backhed, F.1    Roswall, J.2    Peng, Y.3
  • 59
    • 84890461111 scopus 로고    scopus 로고
    • Decreased gut microbiota diversity, delayed Bacteroidetes colonisation and reduced Th1 responses in infants delivered by caesarean section
    • Jakobsson, H.E., Abrahamsson, T.R., Jenmalm, M.C., et al. Decreased gut microbiota diversity, delayed Bacteroidetes colonisation and reduced Th1 responses in infants delivered by caesarean section. Gut 63 (2014), 559–566.
    • (2014) Gut , vol.63 , pp. 559-566
    • Jakobsson, H.E.1    Abrahamsson, T.R.2    Jenmalm, M.C.3
  • 60
    • 84920457959 scopus 로고    scopus 로고
    • Cesarean section and chronic immune disorders
    • Sevelsted, A., Stokholm, J., Bonnelykke, K., et al. Cesarean section and chronic immune disorders. Pediatrics 135 (2015), e92–e98.
    • (2015) Pediatrics , vol.135 , pp. e92-e98
    • Sevelsted, A.1    Stokholm, J.2    Bonnelykke, K.3
  • 61
    • 84869121833 scopus 로고    scopus 로고
    • Can nutritional modulation of maternal intestinal microbiota influence the development of the infant gastrointestinal tract?
    • Thum, C., Cookson, A.L., Otter, D.E., et al. Can nutritional modulation of maternal intestinal microbiota influence the development of the infant gastrointestinal tract?. J Nutr 142 (2012), 1921–1928.
    • (2012) J Nutr , vol.142 , pp. 1921-1928
    • Thum, C.1    Cookson, A.L.2    Otter, D.E.3
  • 62
    • 84896822568 scopus 로고    scopus 로고
    • Impact of diet in shaping gut microbiota revealed by a comparative study in infants during the six months of life
    • Fan, W., Huo, G., Li, X., et al. Impact of diet in shaping gut microbiota revealed by a comparative study in infants during the six months of life. J Microbiol Biotechnol 24 (2014), 133–143.
    • (2014) J Microbiol Biotechnol , vol.24 , pp. 133-143
    • Fan, W.1    Huo, G.2    Li, X.3
  • 63
    • 78049504118 scopus 로고    scopus 로고
    • Examination of faecal Bifidobacterium populations in breast- and formula-fed infants during the first 18 months of life
    • Roger, L.C., Costabile, A., Holland, D.T., et al. Examination of faecal Bifidobacterium populations in breast- and formula-fed infants during the first 18 months of life. Microbiology 156 (2010), 3329–3341.
    • (2010) Microbiology , vol.156 , pp. 3329-3341
    • Roger, L.C.1    Costabile, A.2    Holland, D.T.3
  • 64
    • 84861659935 scopus 로고    scopus 로고
    • Human milk oligosaccharide consumption by intestinal microbiota
    • Marcobal, A., Sonnenburg, J.L., Human milk oligosaccharide consumption by intestinal microbiota. Clin Microbiol Infect 18:Suppl 4 (2012), 12–15.
    • (2012) Clin Microbiol Infect , vol.18 , pp. 12-15
    • Marcobal, A.1    Sonnenburg, J.L.2
  • 65
    • 79953044785 scopus 로고    scopus 로고
    • Longitudinal analysis of macronutrients and minerals in human milk produced by mothers of preterm infants
    • Bauer, J., Gerss, J., Longitudinal analysis of macronutrients and minerals in human milk produced by mothers of preterm infants. Clin Nutr 30 (2011), 215–220.
    • (2011) Clin Nutr , vol.30 , pp. 215-220
    • Bauer, J.1    Gerss, J.2
  • 66
    • 58749112734 scopus 로고    scopus 로고
    • A core gut microbiome in obese and lean twins
    • Turnbaugh, P.J., Hamady, M., Yatsunenko, T., et al. A core gut microbiome in obese and lean twins. Nature 457 (2009), 480–484.
    • (2009) Nature , vol.457 , pp. 480-484
    • Turnbaugh, P.J.1    Hamady, M.2    Yatsunenko, T.3
  • 67
    • 84879503590 scopus 로고    scopus 로고
    • The individual-specific and diverse nature of the preterm infant microbiota
    • Barrett, E., Kerr, C., Murphy, K., et al. The individual-specific and diverse nature of the preterm infant microbiota. Arch Dis Child Fetal Neonatal Ed 98 (2013), F334–F340.
    • (2013) Arch Dis Child Fetal Neonatal Ed , vol.98 , pp. F334-F340
    • Barrett, E.1    Kerr, C.2    Murphy, K.3
  • 69
    • 84963682759 scopus 로고    scopus 로고
    • Regulation of prefrontal cortex myelination by the microbiota
    • Hoban, A.E., Stilling, R.M., Ryan, F.J., et al. Regulation of prefrontal cortex myelination by the microbiota. Transl Psychiatry, 6, 2016, e774.
    • (2016) Transl Psychiatry , vol.6 , pp. e774
    • Hoban, A.E.1    Stilling, R.M.2    Ryan, F.J.3
  • 70
    • 85026846520 scopus 로고    scopus 로고
    • Infant gut microbiome associated with cognitive development
    • Carlson, A.L., Xia, K., Azcarate-Peril, M.A., et al. Infant gut microbiome associated with cognitive development. Biol Psychiatry 83 (2018), 148–159.
    • (2018) Biol Psychiatry , vol.83 , pp. 148-159
    • Carlson, A.L.1    Xia, K.2    Azcarate-Peril, M.A.3
  • 71
    • 34547129847 scopus 로고    scopus 로고
    • Development of the human infant intestinal microbiota
    • Palmer, C., Bik, E.M., DiGiulio, D.B., et al. Development of the human infant intestinal microbiota. PLoS Biol, 5, 2007, e177.
    • (2007) PLoS Biol , vol.5 , pp. e177
    • Palmer, C.1    Bik, E.M.2    DiGiulio, D.B.3
  • 72
    • 84875904427 scopus 로고    scopus 로고
    • Long-term monitoring of the human intestinal microbiota composition
    • Epub ahead of print. October 15, 2012.
    • Rajilic-Stojanovic, M., Heilig, H.G., Tims, S., et al. Long-term monitoring of the human intestinal microbiota composition. Environ Microbiol, 2012 Epub ahead of print. October 15, 2012. https://doi.org/10.1111/1462-2920.12023.
    • (2012) Environ Microbiol
    • Rajilic-Stojanovic, M.1    Heilig, H.G.2    Tims, S.3
  • 73
    • 0345146928 scopus 로고    scopus 로고
    • Mapping cortical change across the human life span
    • Sowell, E.R., Peterson, B.S., Thompson, P.M., et al. Mapping cortical change across the human life span. Nat Neurosci 6 (2003), 309–315.
    • (2003) Nat Neurosci , vol.6 , pp. 309-315
    • Sowell, E.R.1    Peterson, B.S.2    Thompson, P.M.3
  • 74
    • 84938273954 scopus 로고    scopus 로고
    • Gut microbiota depletion from early adolescence in mice: implications for brain and behaviour
    • Desbonnet, L., Clarke, G., Traplin, A., et al. Gut microbiota depletion from early adolescence in mice: implications for brain and behaviour. Brain Behav Immun 48 (2015), 165–173.
    • (2015) Brain Behav Immun , vol.48 , pp. 165-173
    • Desbonnet, L.1    Clarke, G.2    Traplin, A.3
  • 75
    • 84955697102 scopus 로고    scopus 로고
    • Antibiotic exposure and the risk for depression, anxiety, or psychosis: a nested case-control study
    • Lurie, I., Yang, Y.X., Haynes, K., et al. Antibiotic exposure and the risk for depression, anxiety, or psychosis: a nested case-control study. J Clin Psychiatry 76 (2015), 1522–1528.
    • (2015) J Clin Psychiatry , vol.76 , pp. 1522-1528
    • Lurie, I.1    Yang, Y.X.2    Haynes, K.3
  • 76
    • 79952756960 scopus 로고    scopus 로고
    • Incomplete recovery and individualized responses of the human distal gut microbiota to repeated antibiotic perturbation
    • Dethlefsen, L., Relman, D.A., Incomplete recovery and individualized responses of the human distal gut microbiota to repeated antibiotic perturbation. Proc Natl Acad Sci U S A 108:Suppl 1 (2011), 4554–4561.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 4554-4561
    • Dethlefsen, L.1    Relman, D.A.2
  • 77
    • 84892828465 scopus 로고    scopus 로고
    • Diet rapidly and reproducibly alters the human gut microbiome
    • David, L.A., Maurice, C.F., Carmody, R.N., et al. Diet rapidly and reproducibly alters the human gut microbiome. Nature 505 (2014), 559–563.
    • (2014) Nature , vol.505 , pp. 559-563
    • David, L.A.1    Maurice, C.F.2    Carmody, R.N.3
  • 78
    • 85028451429 scopus 로고    scopus 로고
    • Seasonal cycling in the gut microbiome of the Hadza hunter-gatherers of Tanzania
    • Smits, S.A., Leach, J., Sonnenburg, E.D., et al. Seasonal cycling in the gut microbiome of the Hadza hunter-gatherers of Tanzania. Science 357 (2017), 802–806.
    • (2017) Science , vol.357 , pp. 802-806
    • Smits, S.A.1    Leach, J.2    Sonnenburg, E.D.3
  • 79
    • 85040520040 scopus 로고    scopus 로고
    • Gut microbiome populations are associated with structure-specific changes in white matter architecture
    • Ong, I.M., Gonzalez, J.G., McIlwain, S.J., et al. Gut microbiome populations are associated with structure-specific changes in white matter architecture. Transl Psychiatry, 8, 2018, 6.
    • (2018) Transl Psychiatry , vol.8 , pp. 6
    • Ong, I.M.1    Gonzalez, J.G.2    McIlwain, S.J.3
  • 80
    • 84954099831 scopus 로고    scopus 로고
    • Diet-induced extinctions in the gut microbiota compound over generations
    • Sonnenburg, E.D., Smits, S.A., Tikhonov, M., et al. Diet-induced extinctions in the gut microbiota compound over generations. Nature 529 (2016), 212–215.
    • (2016) Nature , vol.529 , pp. 212-215
    • Sonnenburg, E.D.1    Smits, S.A.2    Tikhonov, M.3
  • 81
    • 80053618114 scopus 로고    scopus 로고
    • Linking long-term dietary patterns with gut microbial enterotypes
    • Wu, G.D., Chen, J., Hoffmann, C., et al. Linking long-term dietary patterns with gut microbial enterotypes. Science 334 (2011), 105–108.
    • (2011) Science , vol.334 , pp. 105-108
    • Wu, G.D.1    Chen, J.2    Hoffmann, C.3
  • 82
    • 84878287270 scopus 로고    scopus 로고
    • Consumption of fermented milk product with probiotic modulates brain activity
    • 401 e1–4
    • Tillisch, K., Labus, J., Kilpatrick, L., et al. Consumption of fermented milk product with probiotic modulates brain activity. Gastroenterology 144 (2013), 1394–1401 401 e1–4.
    • (2013) Gastroenterology , vol.144 , pp. 1394-1401
    • Tillisch, K.1    Labus, J.2    Kilpatrick, L.3
  • 83
    • 85029689146 scopus 로고    scopus 로고
    • Effect of Lactobacillus rhamnosus HN001 in pregnancy on postpartum symptoms of depression and anxiety: a randomised double-blind placebo-controlled trial
    • Slykerman, R.F., Hood, F., Wickens, K., et al. Effect of Lactobacillus rhamnosus HN001 in pregnancy on postpartum symptoms of depression and anxiety: a randomised double-blind placebo-controlled trial. EBioMedicine 24 (2017), 159–165.
    • (2017) EBioMedicine , vol.24 , pp. 159-165
    • Slykerman, R.F.1    Hood, F.2    Wickens, K.3
  • 84
    • 85021338194 scopus 로고    scopus 로고
    • Probiotic Bifidobacterium longum NCC3001 reduces depression scores and alters brain activity: a pilot study in patients with irritable bowel syndrome
    • Pinto-Sanchez, M.I., Hall, G.B., Ghajar, K., et al. Probiotic Bifidobacterium longum NCC3001 reduces depression scores and alters brain activity: a pilot study in patients with irritable bowel syndrome. Gastroenterology 153 (2017), 448–459 e8.
    • (2017) Gastroenterology , vol.153 , pp. 448-459 e8
    • Pinto-Sanchez, M.I.1    Hall, G.B.2    Ghajar, K.3
  • 85
    • 85021710126 scopus 로고    scopus 로고
    • A double-blind, randomized, placebo-controlled trial of Lactobacillus helveticus and Bifidobacterium longum for the symptoms of depression
    • Romijn, A.R., Rucklidge, J.J., Kuijer, R.G., et al. A double-blind, randomized, placebo-controlled trial of Lactobacillus helveticus and Bifidobacterium longum for the symptoms of depression. Aust N Z J Psychiatry 51 (2017), 810–821.
    • (2017) Aust N Z J Psychiatry , vol.51 , pp. 810-821
    • Romijn, A.R.1    Rucklidge, J.J.2    Kuijer, R.G.3
  • 86
    • 84961202243 scopus 로고    scopus 로고
    • Clinical and metabolic response to probiotic administration in patients with major depressive disorder: a randomized, double-blind, placebo-controlled trial
    • Akkasheh, G., Kashani-Poor, Z., Tajabadi-Ebrahimi, M., et al. Clinical and metabolic response to probiotic administration in patients with major depressive disorder: a randomized, double-blind, placebo-controlled trial. Nutrition 32 (2016), 315–320.
    • (2016) Nutrition , vol.32 , pp. 315-320
    • Akkasheh, G.1    Kashani-Poor, Z.2    Tajabadi-Ebrahimi, M.3
  • 87
    • 84977109319 scopus 로고    scopus 로고
    • Probiotic Lactobacillus casei strain Shirota relieves stress-associated symptoms by modulating the gut-brain interaction in human and animal models
    • Takada, M., Nishida, K., Kataoka-Kato, A., et al. Probiotic Lactobacillus casei strain Shirota relieves stress-associated symptoms by modulating the gut-brain interaction in human and animal models. Neurogastroenterol Motil 28 (2016), 1027–1036.
    • (2016) Neurogastroenterol Motil , vol.28 , pp. 1027-1036
    • Takada, M.1    Nishida, K.2    Kataoka-Kato, A.3
  • 88
    • 84994275309 scopus 로고    scopus 로고
    • Bifidobacterium longum 1714 as a translational psychobiotic: modulation of stress, electrophysiology and neurocognition in healthy volunteers
    • Allen, A.P., Hutch, W., Borre, Y.E., et al. Bifidobacterium longum 1714 as a translational psychobiotic: modulation of stress, electrophysiology and neurocognition in healthy volunteers. Transl Psychiatry, 6, 2016, e939.
    • (2016) Transl Psychiatry , vol.6 , pp. e939
    • Allen, A.P.1    Hutch, W.2    Borre, Y.E.3
  • 89
    • 85007233429 scopus 로고    scopus 로고
    • Lost in translation? The potential psychobiotic Lactobacillus rhamnosus (JB-1) fails to modulate stress or cognitive performance in healthy male subjects
    • Kelly, J.R., Allen, A.P., Temko, A., et al. Lost in translation? The potential psychobiotic Lactobacillus rhamnosus (JB-1) fails to modulate stress or cognitive performance in healthy male subjects. Brain Behav Immun 61 (2017), 50–59.
    • (2017) Brain Behav Immun , vol.61 , pp. 50-59
    • Kelly, J.R.1    Allen, A.P.2    Temko, A.3
  • 90
    • 84992187971 scopus 로고    scopus 로고
    • Probiotic administration among free-living older adults: a double blinded, randomized, placebo-controlled clinical trial
    • Ostlund-Lagerstrom, L., Kihlgren, A., Repsilber, D., et al. Probiotic administration among free-living older adults: a double blinded, randomized, placebo-controlled clinical trial. Nutr J, 15, 2016, 80.
    • (2016) Nutr J , vol.15 , pp. 80
    • Ostlund-Lagerstrom, L.1    Kihlgren, A.2    Repsilber, D.3
  • 91
    • 84937636483 scopus 로고    scopus 로고
    • Prebiotic intake reduces the waking cortisol response and alters emotional bias in healthy volunteers
    • Schmidt, K., Cowen, P.J., Harmer, C.J., et al. Prebiotic intake reduces the waking cortisol response and alters emotional bias in healthy volunteers. Psychopharmacology (Berl) 232 (2015), 1793–1801.
    • (2015) Psychopharmacology (Berl) , vol.232 , pp. 1793-1801
    • Schmidt, K.1    Cowen, P.J.2    Harmer, C.J.3
  • 92
    • 85051622977 scopus 로고    scopus 로고
    • Effects of rifaximin on central responses to social stress-a pilot experiment
    • Wang, H., Braun, C., Enck, P., Effects of rifaximin on central responses to social stress-a pilot experiment. Neurotherapeutics 15 (2018), 807–818.
    • (2018) Neurotherapeutics , vol.15 , pp. 807-818
    • Wang, H.1    Braun, C.2    Enck, P.3
  • 93
    • 85013756511 scopus 로고    scopus 로고
    • Targeting the microbiota-gut-brain axis: prebiotics have anxiolytic and antidepressant-like effects and reverse the impact of chronic stress in mice
    • Burokas, A., Arboleya, S., Moloney, R.D., et al. Targeting the microbiota-gut-brain axis: prebiotics have anxiolytic and antidepressant-like effects and reverse the impact of chronic stress in mice. Biol Psychiatry 82 (2017), 472–487.
    • (2017) Biol Psychiatry , vol.82 , pp. 472-487
    • Burokas, A.1    Arboleya, S.2    Moloney, R.D.3
  • 94
    • 77957142793 scopus 로고    scopus 로고
    • Effects of the probiotic Bifidobacterium infantis in the maternal separation model of depression
    • Desbonnet, L., Garrett, L., Clarke, G., et al. Effects of the probiotic Bifidobacterium infantis in the maternal separation model of depression. Neuroscience 170 (2010), 1179–1188.
    • (2010) Neuroscience , vol.170 , pp. 1179-1188
    • Desbonnet, L.1    Garrett, L.2    Clarke, G.3
  • 95
    • 84936803964 scopus 로고    scopus 로고
    • The prebiotics 3’Sialyllactose and 6’Sialyllactose diminish stressor-induced anxiety-like behavior and colonic microbiota alterations: evidence for effects on the gut-brain axis
    • Tarr, A.J., Galley, J.D., Fisher, S.E., et al. The prebiotics 3’Sialyllactose and 6’Sialyllactose diminish stressor-induced anxiety-like behavior and colonic microbiota alterations: evidence for effects on the gut-brain axis. Brain Behav Immun 50 (2015), 166–177.
    • (2015) Brain Behav Immun , vol.50 , pp. 166-177
    • Tarr, A.J.1    Galley, J.D.2    Fisher, S.E.3
  • 96
    • 85036528107 scopus 로고    scopus 로고
    • A meta-analysis of the use of probiotics to alleviate depressive symptoms
    • Ng, Q.X., Peters, C., Ho, C.Y.X., et al. A meta-analysis of the use of probiotics to alleviate depressive symptoms. J Affect Disord 228 (2018), 13–19.
    • (2018) J Affect Disord , vol.228 , pp. 13-19
    • Ng, Q.X.1    Peters, C.2    Ho, C.Y.X.3
  • 97
    • 85017331192 scopus 로고    scopus 로고
    • Probiotics and subclinical psychological symptoms in healthy participants: a systematic review and meta-analysis
    • McKean, J., Naug, H., Nikbakht, E., et al. Probiotics and subclinical psychological symptoms in healthy participants: a systematic review and meta-analysis. J Altern Complement Med 23 (2017), 249–258.
    • (2017) J Altern Complement Med , vol.23 , pp. 249-258
    • McKean, J.1    Naug, H.2    Nikbakht, E.3
  • 98
    • 84866146940 scopus 로고    scopus 로고
    • Diversity, stability and resilience of the human gut microbiota
    • Lozupone, C.A., Stombaugh, J.I., Gordon, J.I., et al. Diversity, stability and resilience of the human gut microbiota. Nature 489 (2012), 220–230.
    • (2012) Nature , vol.489 , pp. 220-230
    • Lozupone, C.A.1    Stombaugh, J.I.2    Gordon, J.I.3
  • 99
    • 85008931775 scopus 로고    scopus 로고
    • Emerging roles for the gut microbiome in autism spectrum disorder
    • Vuong, H.E., Hsiao, E.Y., Emerging roles for the gut microbiome in autism spectrum disorder. Biol Psychiatry 81 (2017), 411–423.
    • (2017) Biol Psychiatry , vol.81 , pp. 411-423
    • Vuong, H.E.1    Hsiao, E.Y.2
  • 100
    • 85029218925 scopus 로고    scopus 로고
    • Gut microbiome in ADHD and its relation to neural reward anticipation
    • Aarts, E., Ederveen, T.H.A., Naaijen, J., et al. Gut microbiome in ADHD and its relation to neural reward anticipation. PLoS One, 12, 2017, e0183509.
    • (2017) PLoS One , vol.12 , pp. e0183509
    • Aarts, E.1    Ederveen, T.H.A.2    Naaijen, J.3
  • 101
    • 85001930733 scopus 로고    scopus 로고
    • Gut microbiota regulate motor deficits and neuroinflammation in a model of Parkinson's disease
    • Sampson, T.R., Debelius, J.W., Thron, T., et al. Gut microbiota regulate motor deficits and neuroinflammation in a model of Parkinson's disease. Cell 167 (2016), 1469–1480 e12.
    • (2016) Cell , vol.167 , pp. 1469-1480 e12
    • Sampson, T.R.1    Debelius, J.W.2    Thron, T.3
  • 102
    • 85019066395 scopus 로고    scopus 로고
    • The gut microbiota and Alzheimer's disease
    • Jiang, C., Li, G., Huang, P., et al. The gut microbiota and Alzheimer's disease. J Alzheimers Dis 58 (2017), 1–15.
    • (2017) J Alzheimers Dis , vol.58 , pp. 1-15
    • Jiang, C.1    Li, G.2    Huang, P.3
  • 103
    • 85041538555 scopus 로고    scopus 로고
    • Gut microbiome alterations in Alzheimer's disease
    • Vogt, N.M., Kerby, R.L., Dill-McFarland, K.A., et al. Gut microbiome alterations in Alzheimer's disease. Sci Rep, 7, 2017, 13537.
    • (2017) Sci Rep , vol.7 , pp. 13537
    • Vogt, N.M.1    Kerby, R.L.2    Dill-McFarland, K.A.3
  • 104
    • 84993945111 scopus 로고    scopus 로고
    • Association of brain amyloidosis with pro-inflammatory gut bacterial taxa and peripheral inflammation markers in cognitively impaired elderly
    • Cattaneo, A., Cattane, N., Galluzzi, S., et al. Association of brain amyloidosis with pro-inflammatory gut bacterial taxa and peripheral inflammation markers in cognitively impaired elderly. Neurobiol Aging 49 (2017), 60–68.
    • (2017) Neurobiol Aging , vol.49 , pp. 60-68
    • Cattaneo, A.1    Cattane, N.2    Galluzzi, S.3
  • 105
    • 84964047906 scopus 로고    scopus 로고
    • Depletion of cultivatable gut microbiota by broad-spectrum antibiotic pretreatment worsens outcome after murine stroke
    • Winek, K., Engel, O., Koduah, P., et al. Depletion of cultivatable gut microbiota by broad-spectrum antibiotic pretreatment worsens outcome after murine stroke. Stroke 47 (2016), 1354–1363.
    • (2016) Stroke , vol.47 , pp. 1354-1363
    • Winek, K.1    Engel, O.2    Koduah, P.3
  • 106
    • 85023768706 scopus 로고    scopus 로고
    • An unexplored brain-gut microbiota axis in stroke
    • Wen, S.W., Wong, C.H.Y., An unexplored brain-gut microbiota axis in stroke. Gut Microbes 8 (2017), 601–606.
    • (2017) Gut Microbes , vol.8 , pp. 601-606
    • Wen, S.W.1    Wong, C.H.Y.2
  • 107
    • 85046857479 scopus 로고    scopus 로고
    • The gut microbiota mediates the anti-seizure effects of the ketogenic diet
    • Olson, C.A., Vuong, H.E., Yano, J.M., et al. The gut microbiota mediates the anti-seizure effects of the ketogenic diet. Cell 173 (2018), 1728–1741 e13.
    • (2018) Cell , vol.173 , pp. 1728-1741 e13
    • Olson, C.A.1    Vuong, H.E.2    Yano, J.M.3
  • 108
    • 84979955472 scopus 로고    scopus 로고
    • Transferring the blues: depression-associated gut microbiota induces neurobehavioural changes in the rat
    • Kelly, J.R., Borre, Y., O'Brien, C., et al. Transferring the blues: depression-associated gut microbiota induces neurobehavioural changes in the rat. J Psychiatr Res 82 (2016), 109–118.
    • (2016) J Psychiatr Res , vol.82 , pp. 109-118
    • Kelly, J.R.1    Borre, Y.2    O'Brien, C.3
  • 109
    • 84963547235 scopus 로고    scopus 로고
    • Gut microbiome remodeling induces depressive-like behaviors through a pathway mediated by the host's metabolism
    • Zheng, P., Zeng, B., Zhou, C., et al. Gut microbiome remodeling induces depressive-like behaviors through a pathway mediated by the host's metabolism. Mol Psychiatry 21 (2016), 786–796.
    • (2016) Mol Psychiatry , vol.21 , pp. 786-796
    • Zheng, P.1    Zeng, B.2    Zhou, C.3
  • 110
    • 85014649400 scopus 로고    scopus 로고
    • Transplantation of fecal microbiota from patients with irritable bowel syndrome alters gut function and behavior in recipient mice
    • De Palma, G., Lynch, M.D., Lu, J., et al. Transplantation of fecal microbiota from patients with irritable bowel syndrome alters gut function and behavior in recipient mice. Sci Transl Med, 9, 2017.
    • (2017) Sci Transl Med , vol.9
    • De Palma, G.1    Lynch, M.D.2    Lu, J.3
  • 111
    • 85021685982 scopus 로고    scopus 로고
    • Brain structure and response to emotional stimuli as related to gut microbial profiles in healthy women
    • Tillisch, K., Mayer, E.A., Gupta, A., et al. Brain structure and response to emotional stimuli as related to gut microbial profiles in healthy women. Psychosom Med 79 (2017), 905–913.
    • (2017) Psychosom Med , vol.79 , pp. 905-913
    • Tillisch, K.1    Mayer, E.A.2    Gupta, A.3
  • 112
    • 84871120114 scopus 로고    scopus 로고
    • Intestinal microbiota in functional bowel disorders: a Rome foundation report
    • Simren, M., Barbara, G., Flint, H.J., et al. Intestinal microbiota in functional bowel disorders: a Rome foundation report. Gut 62 (2013), 159–176.
    • (2013) Gut , vol.62 , pp. 159-176
    • Simren, M.1    Barbara, G.2    Flint, H.J.3
  • 113
    • 85029714663 scopus 로고    scopus 로고
    • Differences in gut microbial composition correlate with regional brain volumes in irritable bowel syndrome
    • Labus, J.S., Hollister, E.B., Jacobs, J., et al. Differences in gut microbial composition correlate with regional brain volumes in irritable bowel syndrome. Microbiome, 5, 2017, 49.
    • (2017) Microbiome , vol.5 , pp. 49
    • Labus, J.S.1    Hollister, E.B.2    Jacobs, J.3
  • 114
    • 84861578319 scopus 로고    scopus 로고
    • An irritable bowel syndrome subtype defined by species-specific alterations in faecal microbiota
    • Jeffery, I.B., O'Toole, P.W., Ohman, L., et al. An irritable bowel syndrome subtype defined by species-specific alterations in faecal microbiota. Gut 61 (2012), 997–1006.
    • (2012) Gut , vol.61 , pp. 997-1006
    • Jeffery, I.B.1    O'Toole, P.W.2    Ohman, L.3
  • 115
    • 85006287897 scopus 로고    scopus 로고
    • Identification of an intestinal microbiota signature associated with severity of irritable bowel syndrome
    • Tap, J., Derrien, M., Tornblom, H., et al. Identification of an intestinal microbiota signature associated with severity of irritable bowel syndrome. Gastroenterology 152 (2017), 111–123 e8.
    • (2017) Gastroenterology , vol.152 , pp. 111-123 e8
    • Tap, J.1    Derrien, M.2    Tornblom, H.3
  • 116
    • 84862829772 scopus 로고    scopus 로고
    • Functional dysbiosis within the gut microbiota of patients with constipated-irritable bowel syndrome
    • Chassard, C., Dapoigny, M., Scott, K.P., et al. Functional dysbiosis within the gut microbiota of patients with constipated-irritable bowel syndrome. Aliment Pharmacol Ther 35 (2012), 828–838.
    • (2012) Aliment Pharmacol Ther , vol.35 , pp. 828-838
    • Chassard, C.1    Dapoigny, M.2    Scott, K.P.3
  • 117
    • 80054857288 scopus 로고    scopus 로고
    • Global and deep molecular analysis of microbiota signatures in fecal samples from patients with irritable bowel syndrome
    • Rajilic-Stojanovic, M., Biagi, E., Heilig, H.G., et al. Global and deep molecular analysis of microbiota signatures in fecal samples from patients with irritable bowel syndrome. Gastroenterology 141 (2011), 1792–1801.
    • (2011) Gastroenterology , vol.141 , pp. 1792-1801
    • Rajilic-Stojanovic, M.1    Biagi, E.2    Heilig, H.G.3
  • 118
    • 79551681952 scopus 로고    scopus 로고
    • Exposure to a social stressor alters the structure of the intestinal microbiota: implications for stressor-induced immunomodulation
    • Bailey, M.T., Dowd, S.E., Galley, J.D., et al. Exposure to a social stressor alters the structure of the intestinal microbiota: implications for stressor-induced immunomodulation. Brain Behav Immun 25 (2011), 397–407.
    • (2011) Brain Behav Immun , vol.25 , pp. 397-407
    • Bailey, M.T.1    Dowd, S.E.2    Galley, J.D.3
  • 119
    • 84904084581 scopus 로고    scopus 로고
    • Exposure to a social stressor disrupts the community structure of the colonic mucosa-associated microbiota
    • Galley, J.D., Nelson, M.C., Yu, Z.T., et al. Exposure to a social stressor disrupts the community structure of the colonic mucosa-associated microbiota. BMC Microbiol, 14, 2014, 189.
    • (2014) BMC Microbiol , vol.14 , pp. 189
    • Galley, J.D.1    Nelson, M.C.2    Yu, Z.T.3
  • 120
    • 38349180713 scopus 로고    scopus 로고
    • Investigating the role of perceived stress on bacterial flora activity and salivary cortisol secretion: a possible mechanism underlying susceptibility to illness
    • Knowles, S.R., Nelson, E.A., Palombo, E.A., Investigating the role of perceived stress on bacterial flora activity and salivary cortisol secretion: a possible mechanism underlying susceptibility to illness. Biol Psychol 77 (2008), 132–137.
    • (2008) Biol Psychol , vol.77 , pp. 132-137
    • Knowles, S.R.1    Nelson, E.A.2    Palombo, E.A.3
  • 121
    • 84883366759 scopus 로고    scopus 로고
    • Food addiction: its prevalence and significant association with obesity in the general population
    • Pedram, P., Wadden, D., Amini, P., et al. Food addiction: its prevalence and significant association with obesity in the general population. PLoS One, 8, 2013, e74832.
    • (2013) PLoS One , vol.8 , pp. e74832
    • Pedram, P.1    Wadden, D.2    Amini, P.3
  • 122
    • 84859587827 scopus 로고    scopus 로고
    • Butyrate and propionate protect against diet-induced obesity and regulate gut hormones via free fatty acid receptor 3-independent mechanisms
    • Lin, H.V., Frassetto, A., Kowalik, E.J. Jr., et al. Butyrate and propionate protect against diet-induced obesity and regulate gut hormones via free fatty acid receptor 3-independent mechanisms. PLoS One, 7, 2012, e35240.
    • (2012) PLoS One , vol.7 , pp. e35240
    • Lin, H.V.1    Frassetto, A.2    Kowalik, E.J.3
  • 123
    • 80755152887 scopus 로고    scopus 로고
    • Responses of gut microbiota and glucose and lipid metabolism to prebiotics in genetic obese and diet-induced leptin-resistant mice
    • Everard, A., Lazarevic, V., Derrien, M., et al. Responses of gut microbiota and glucose and lipid metabolism to prebiotics in genetic obese and diet-induced leptin-resistant mice. Diabetes 60 (2011), 2775–2786.
    • (2011) Diabetes , vol.60 , pp. 2775-2786
    • Everard, A.1    Lazarevic, V.2    Derrien, M.3
  • 124
    • 85052373350 scopus 로고    scopus 로고
    • Correlation of tryptophan metabolites with connectivity of extended central reward network in healthy subjects
    • Osadchiy, V., Labus, J.S., Gupta, A., et al. Correlation of tryptophan metabolites with connectivity of extended central reward network in healthy subjects. PLoS One, 13, 2018, e0201772.
    • (2018) PLoS One , vol.13 , pp. e0201772
    • Osadchiy, V.1    Labus, J.S.2    Gupta, A.3
  • 125
    • 33845874101 scopus 로고    scopus 로고
    • An obesity-associated gut microbiome with increased capacity for energy harvest
    • Turnbaugh, P.J., Ley, R.E., Mahowald, M.A., et al. An obesity-associated gut microbiome with increased capacity for energy harvest. Nature 444 (2006), 1027–1031.
    • (2006) Nature , vol.444 , pp. 1027-1031
    • Turnbaugh, P.J.1    Ley, R.E.2    Mahowald, M.A.3
  • 126
    • 77950250064 scopus 로고    scopus 로고
    • Metabolic syndrome and altered gut microbiota in mice lacking Toll-like receptor 5
    • Vijay-Kumar, M., Aitken, J.D., Carvalho, F.A., et al. Metabolic syndrome and altered gut microbiota in mice lacking Toll-like receptor 5. Science 328 (2010), 228–231.
    • (2010) Science , vol.328 , pp. 228-231
    • Vijay-Kumar, M.1    Aitken, J.D.2    Carvalho, F.A.3
  • 127
    • 84951067967 scopus 로고    scopus 로고
    • Gut microbiota interacts with brain microstructure and function
    • Fernandez-Real, J.M., Serino, M., Blasco, G., et al. Gut microbiota interacts with brain microstructure and function. J Clin Endocrinol Metab 100 (2015), 4505–4513.
    • (2015) J Clin Endocrinol Metab , vol.100 , pp. 4505-4513
    • Fernandez-Real, J.M.1    Serino, M.2    Blasco, G.3
  • 128
    • 60549086580 scopus 로고    scopus 로고
    • Human gut microbiota in obesity and after gastric bypass
    • Zhang, H., DiBaise, J.K., Zuccolo, A., et al. Human gut microbiota in obesity and after gastric bypass. Proc Natl Acad Sci U S A 106 (2009), 2365–2370.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 2365-2370
    • Zhang, H.1    DiBaise, J.K.2    Zuccolo, A.3
  • 129
    • 80051545971 scopus 로고    scopus 로고
    • Metabolic surgery profoundly influences gut microbial-host metabolic cross-talk
    • Li, J.V., Ashrafian, H., Bueter, M., et al. Metabolic surgery profoundly influences gut microbial-host metabolic cross-talk. Gut 60 (2011), 1214–1223.
    • (2011) Gut , vol.60 , pp. 1214-1223
    • Li, J.V.1    Ashrafian, H.2    Bueter, M.3
  • 130
    • 84924210824 scopus 로고    scopus 로고
    • Effects of surgical and dietary weight loss therapy for obesity on gut microbiota composition and nutrient absorption
    • Damms-Machado, A., Mitra, S., Schollenberger, A.E., et al. Effects of surgical and dietary weight loss therapy for obesity on gut microbiota composition and nutrient absorption. Biomed Res Int, 2015, 2015, 806248.
    • (2015) Biomed Res Int , vol.2015 , pp. 806248
    • Damms-Machado, A.1    Mitra, S.2    Schollenberger, A.E.3
  • 131
    • 78650037263 scopus 로고    scopus 로고
    • Differential adaptation of human gut microbiota to bariatric surgery-induced weight loss: links with metabolic and low-grade inflammation markers
    • Furet, J.P., Kong, L.C., Tap, J., et al. Differential adaptation of human gut microbiota to bariatric surgery-induced weight loss: links with metabolic and low-grade inflammation markers. Diabetes 59 (2010), 3049–3057.
    • (2010) Diabetes , vol.59 , pp. 3049-3057
    • Furet, J.P.1    Kong, L.C.2    Tap, J.3
  • 132
    • 84888133800 scopus 로고    scopus 로고
    • Metagenomic sequencing of the human gut microbiome before and after bariatric surgery in obese patients with type 2 diabetes: correlation with inflammatory and metabolic parameters
    • Graessler, J., Qin, Y., Zhong, H., et al. Metagenomic sequencing of the human gut microbiome before and after bariatric surgery in obese patients with type 2 diabetes: correlation with inflammatory and metabolic parameters. Pharmacogenomics J 13 (2013), 514–522.
    • (2013) Pharmacogenomics J , vol.13 , pp. 514-522
    • Graessler, J.1    Qin, Y.2    Zhong, H.3
  • 133
    • 84876139394 scopus 로고    scopus 로고
    • Conserved shifts in the gut microbiota due to gastric bypass reduce host weight and adiposity
    • Liou, A.P., Paziuk, M., Luevano, J.M. Jr., et al. Conserved shifts in the gut microbiota due to gastric bypass reduce host weight and adiposity. Sci Transl Med, 5, 2013, 178ra41.
    • (2013) Sci Transl Med , vol.5 , pp. 178ra41
    • Liou, A.P.1    Paziuk, M.2    Luevano, J.M.3
  • 134
    • 84938559816 scopus 로고    scopus 로고
    • Roux-en-Y gastric bypass and vertical banded gastroplasty induce long-term changes on the human gut microbiome contributing to fat mass regulation
    • Tremaroli, V., Karlsson, F., Werling, M., et al. Roux-en-Y gastric bypass and vertical banded gastroplasty induce long-term changes on the human gut microbiome contributing to fat mass regulation. Cell Metab 22 (2015), 228–238.
    • (2015) Cell Metab , vol.22 , pp. 228-238
    • Tremaroli, V.1    Karlsson, F.2    Werling, M.3
  • 135
    • 85027945471 scopus 로고    scopus 로고
    • Microbiota and neurodevelopmental windows: implications for brain disorders
    • Borre, Y.E., O'Keeffe, G.W., Clarke, G., et al. Microbiota and neurodevelopmental windows: implications for brain disorders. Trends Mol Med 20 (2014), 509–518.
    • (2014) Trends Mol Med , vol.20 , pp. 509-518
    • Borre, Y.E.1    O'Keeffe, G.W.2    Clarke, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.