TLR ligands and butyrate increase Pyy expression through two distinct but inter-regulated pathways

Cellular Microbiology

Volumn 19, Issue 2, 2017, Pages

  Larraufie, Pierre ^a   Doré, Joël ^a   Lapaque, Nicolas ^a   Blottière, Hervé M ^a  

^a UNIVERSITÉ PARIS SACLAY   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BUTYRIC ACID; DEFENSIN; GLUCAGON LIKE PEPTIDE 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INSULIN; PEPTIDE YY; PROGLUCAGON; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR AGONIST; BUTYRIC ACID DERIVATIVE;

ARTICLE; BACTERIUM; CONTROLLED STUDY; ENTEROENDOCRINE CELL; FERMENTATION; FOOD INTAKE; GENE; GENE EXPRESSION; HUMAN; HUMAN CELL; INSULIN RELEASE; INTESTINE EPITHELIUM; INTESTINE MOTILITY; INTESTINE MUCOSA PERMEABILITY; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; PANETH CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PYY GENE; REGULATORY MECHANISM; TLR GENE; TLR4 GENE; AGONISTS; BIOSYNTHESIS; CELL LINE; GENE EXPRESSION REGULATION; METABOLISM; SECRETION (PROCESS);

BUTYRATES; CELL LINE; ENTEROENDOCRINE CELLS; GENE EXPRESSION REGULATION; GLUCAGON-LIKE PEPTIDE 1; HUMANS; NF-KAPPA B; PEPTIDE YY; TOLL-LIKE RECEPTORS;

EID: 84982994263     PISSN: 14625814     EISSN: 14625822     Source Type: Journal    
DOI: 10.1111/cmi.12648     Document Type: Article

References (53)

1. Abreu, M.T. (2010) Toll-like receptor signalling in the intestinal epithelium: how bacterial recognition shapes intestinal function. Nat Rev Immunol 10: 131–44.
2. Adrian, T.E., Ferri, G.L., Bacarese-Hamilton, A.J., Fuessl, H.S., Polak, J.M., and Bloom, S.R. (1985) Human distribution and release of a putative new gut hormone, peptide YY. Gastroenterology 89: 1070–7.
3. Adrian, T.E., Savage, A.P., Bacarese-Hamilton, A.J., Wolfe, K., Besterman, H.S., and Bloom, S.R. (1986) Peptide YY abnormalities in gastrointestinal diseases. Gastroenterology 90: 379–84.
4. Akira, S., Uematsu, S., and Takeuchi, O. (2006) Pathogen recognition and innate immunity. Cell 124: 783–801.
5. Anitha, M., Vijay-Kumar, M., Sitaraman, S.V., Gewirtz, A.T., and Srinivasan, S. (2012) Gut microbial products regulate murine gastrointestinal motility via Toll-like receptor 4 signaling. Gastroenterology 143: 1006–16.e4.
6. Batterham, R.L., and Bloom, S.R. (2003) The gut hormone peptide YY regulates appetite. Ann N Y Acad Sci 994: 162–8.
7. Besten, G., den Eunen, K., van Groen, A.K., Venema, K., Reijngoud, D.-J., and Bakker, B.M. (2013) The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism. J Lipid Res 54: 2325–40.
8. Bogunovic, M., Davé, S.H., Tilstra, J.S., Chang, D.T.W., Harpaz, N., Xiong, H., et al. (2007) Enteroendocrine cells express functional Toll-like receptors. Am J Physiol Gastrointest Liver Physiol 292: G1770–83.
9. Camilleri, M. (2015) Peripheral mechanisms in appetite regulation. Gastroenterology 148: 1219–33.
10. Cani, P.D., Hoste, S., Guiot, Y., and Delzenne, N.M. (2007) Dietary non-digestible carbohydrates promote L-cell differentiation in the proximal colon of rats. Br J Nutr 98: 32–7.
11. Cummings, J.H. (1981) Short chain fatty acids in the human colon. Gut 22: 763–79.
12. El-Jamal, N., Erdual, E., Neunlist, M., Koriche, D., Dubuquoy, C., Maggiotto, F., et al. (2014) Glugacon-like peptide-2: broad receptor expression, limited therapeutic effect on intestinal inflammation and novel role in liver regeneration. Am J Physiol Gastrointest Liver Physiol 307: G274–85.
13. El-Salhy, M., Gundersen, D., Hatlebakk, J.G., and Hausken, T. (2012) High densities of serotonin and peptide YY cells in the colon of patients with lymphocytic colitis. World J Gastroenterol 18: 6070–5.
14. Exton, M.S. (1997) Infection-induced anorexia: active host defence strategy. Appetite 29: 369–83.
15. Ferrier, L., Segain, J.-P., Bonnet, C., Cherbut, C., Lehur, P.-A., Jarry, A., et al. (2002) Functional mapping of NPY/PYY receptors in rat and human gastro-intestinal tract. Peptides 23: 1765–1771.
16. Ferrier, L., Segain, J.P., Pacaud, P., Cherbut, C., Loirand, G., Galmiche, J.P., and Blottière, H.M. (2000) Pathways and receptors involved in peptide YY induced contraction of rat proximal colonic muscle in vitro. Gut 46: 370–5.
17. Grasa, L., Abecia, L., Forcén, R., Castro, M., Jalón, J.A.G., de Latorre, E., et al. (2015) Antibiotic-induced depletion of murine microbiota induces mild inflammation and changes in toll-like receptor patterns and intestinal motility. Microb Ecol.
18. Graves, C.L., Harden, S.W., LaPato, M., Nelson, M., Amador, B., Sorenson, H., et al. (2014) A method for high purity intestinal epithelial cell culture from adult human and murine tissues for the investigation of innate immune function. J Immunol Methods 414: 20–31.
19. Gunawardene, A.R., Corfe, B.M., and Staton, C.A. (2011) Classification and functions of enteroendocrine cells of the lower gastrointestinal tract. Int J Exp Pathol 92: 219–31.
20. Habib, A.M., Richards, P., Cairns, L.S., Rogers, G.J., Bannon, C.A.M., Parker, H.E., et al. (2012) Overlap of endocrine hormone expression in the mouse intestine revealed by transcriptional profiling and flow cytometry. Endocrinology 153: 3054–65.
21. Heil, F., Hemmi, H., Hochrein, H., Ampenberger, F., Kirschning, C., Akira, S., et al. (2004) Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8. Science 303: 1526–9.
22. Higashiguchi, T., Noguchi, Y., Noffsinger, A., Fischer, J.E., and Hasselgren, P.O. (1994) Sepsis increases production of total secreted proteins, vasoactive intestinal peptide, and peptide YY in isolated rat enterocytes. Am J Surg 168: 251–6.
23. Hirasawa, A., Tsumaya, K., Awaji, T., Katsuma, S., Adachi, T., Yamada, M., et al. (2005) Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120. Nat Med 11: 90–4.
24. Hogan, A.E., Tobin, A.M., Ahern, T., Corrigan, M.A., Gaoatswe, G., Jackson, R., et al. (2011) Glucagon-like peptide-1 (GLP-1) and the regulation of human invariant natural killer T cells: lessons from obesity, diabetes and psoriasis. Diabetologia 54: 2745–54.
25. Jang, H.-J., Kokrashvili, Z., Theodorakis, M.J., Carlson, O.D., Kim, B.-J., Zhou, J., et al. (2007) Gut-expressed gustducin and taste receptors regulate secretion of glucagon-like peptide-1. Proc Natl Acad Sci U S A 104: 15069–74.
26. Janssen, P., Rotondo, A., Mulé, F., and Tack, J. (2012) Review article: a comparison of glucagon-like peptides 1 and 2. Aliment Pharmacol Ther 37: 18–36.
27. Karra, E., and Batterham, R.L. (2010) The role of gut hormones in the regulation of body weight and energy homeostasis. Mol Cell Endocrinol 316: 120–8.
28. Kawai, T., and Akira, S. (2007) Signaling to NF-kappaB by Toll-like receptors. Trends Mol Med 13: 460–9.
29. Khosravi, Y., Seow, S.W., Amoyo, A.A., Chiow, K.H., Tan, T.L., Wong, W.Y., et al. (2015) Helicobacter pylori infection can affect energy modulating hormones and body weight in germ free mice. Sci Rep 5: 8731.
30. Kidd, M., Gustafsson, b.i., Drozdov, I., and Modlin, i.m. (2009) IL1β- and LPS-induced serotonin secretion is increased in EC cells derived from Crohn's disease. Neurogastroenterol Motil 21: 439–450.
31. Kim, H.S., Lim, J.H., Park, H., and Lee, S.I. (2010) Increased immunoendocrine cells in intestinal mucosa of postinfectious irritable bowel syndrome patients 3 years after acute Shigella infection—an observation in a small case control study. Yonsei Med J 51: 45–51.
32. Lee, J., Mo, J.-H., Katakura, K., Alkalay, I., Rucker, A.N., Liu, Y.-T., et al. (2006) Maintenance of colonic homeostasis by distinctive apical TLR9 signalling in intestinal epithelial cells. Nat Cell Biol 8: 1327–36.
33. Macia, L., Yulyaningsih, E., Pangon, L., Nguyen, A.D., Lin, S., Shi, Y.C., et al. (2012) Neuropeptide Y1 receptor in immune cells regulates inflammation and insulin resistance associated with diet-induced obesity. Diabetes 61: 3228–38.
34. Mathelier, A., Zhao, X., Zhang, A.W., Parcy, F., Worsley-Hunt, R., Arenillas, D.J., et al. (2014) JASPAR 2014: an extensively expanded and updated open-access database of transcription factor binding profiles. Nucleic Acids Res 42: D142–7.
35. Murray, M.J., and Murray, A.B. (1979) Anorexia of infection as a mechanism of host defense. Am J Clin Nutr 32: 593–6.
36. Nevé, B.L., and Daniel, H. (2011) Selected tetrapeptides lead to a GLP-1 release from the human enteroendocrine cell line NCI-H716. Regul Pept 167: 14–20.
37. Palazzo, M., Balsari, A., Rossini, A., Selleri, S., Calcaterra, C., Gariboldi, S., et al. (2007) Activation of enteroendocrine cells via TLRs induces hormone, chemokine, and defensin secretion. J Immunol 178: 4296–303.
38. Parker, H.E., Gribble, F.M., and Reimann, F. (2014) The role of gut endocrine cells in control of metabolism and appetite. Exp Physiol 99: 1116–20.
39. Pfluger, P.T., Kampe, J., Castaneda, T.R., Vahl, T., D'Alessio, D.A., Kruthaupt, T., et al. (2007) Effect of human body weight changes on circulating levels of peptide YY and peptide YY3-36. J Clin Endocrinol Metab 92: 583–8.
40. Rehfeld, J.F. (1998) The new biology of gastrointestinal hormones. Physiol Rev 78: 1087–108.
41. Reimann, F., Tolhurst, G., and Gribble, F.M. (2012) G-protein-coupled receptors in intestinal chemosensation. Cell Metab 15: 421–31.
42. Reimer, R.A. (2001) A Human Cellular Model for Studying the Regulation of Glucagon-Like Peptide-1 Secretion. Endocrinology 142: 4522–4528.
43. Rondas, D., D'Hertog, W., Overbergh, L., and Mathieu, C. (2013) Glucagon-like peptide-1: modulator of β-cell dysfunction and death. Diabetes Obes Metab 15(Suppl 3): 185–92.
44. Rumio, C., Sommariva, M., Sfondrini, L., Palazzo, M., Morelli, D., Viganò, L., et al. (2012) Induction of Paneth cell degranulation by orally administered Toll-like receptor ligands. J Cell Physiol 227: 1107–13.
45. Santaolalla, R., Fukata, M., and Abreu, M.T. (2011) Innate immunity in the small intestine. Curr Opin Gastroenterol 27: 125–31.
46. Selleri, S., Palazzo, M., Deola, S., Wang, E., Balsari, A., Marincola, F.M., and Rumio, C. (2008) Induction of pro-inflammatory programs in enteroendocrine cells by the Toll-like receptor agonists flagellin and bacterial LPS. Int Immunol 20: 961–70.
47. Silva, A.D., Salem, V., Long, C.J., Makwana, A., Newbould, R.D., Rabiner, E.A., et al. (2011) The gut hormones PYY 3-36 and GLP-1 7-36 amide reduce food intake and modulate brain activity in appetite centers in humans. Cell Metab 14: 700–6.
48. Sternini, C., Anselmi, L., and Rozengurt, E. (2008) Enteroendocrine cells: a site of “taste” in gastrointestinal chemosensing. Curr Opin Endocrinol Diabetes Obes 15: 73–8.
49. Svendsen, B., Pedersen, J., Jacob Wewer Albrechtsen, N., Hartmann, B., Toräng, S., Rehfeld, J.F., et al. (2014) An analysis of co-secretion and co-expression of gut hormones from male rat proximal and distal small intestine. Endocrinology 156: 847–57.
50. 2 receptors. Br J Pharmacol 164: 471–84.
51. Vijay-Kumar, M., Aitken, J.D., Carvalho, F.A., Cullender, T.C., Mwangi, S., Srinivasan, S., et al. (2010) Metabolic syndrome and altered gut microbiota in mice lacking Toll-like receptor 5. Science 328: 228–31.
52. Worthington, J.J., Samuelson, L.C., Grencis, R.K., and McLaughlin, J.T. (2013) Adaptive immunity alters distinct host feeding pathways during nematode induced inflammation, a novel mechanism in parasite expulsion. PLoS Pathog 9: e1003122.
53. Yusta, B., Baggio, L.L., Koehler, J., Holland, D., Cao, X., Pinnell, L.J., et al. (2015) GLP-1R agonists modulate enteric immune responses through the intestinal intraepithelial lymphocyte GLP-1R. Diabetes 64: 2537–49.