-
2
-
-
25444461647
-
Functional properties and lineage relationship of CD8+ T-cell subsets identified by expression of IL-7 receptor alpha and CD62L
-
Bachmann MF, Wolint P, Schwarz K, et al. Functional properties and lineage relationship of CD8+ T-cell subsets identified by expression of IL-7 receptor alpha and CD62L. J Immunol 2005; 175(7): 4686-4696.
-
(2005)
J Immunol
, vol.175
, Issue.7
, pp. 4686-4696
-
-
Bachmann, M.F.1
Wolint, P.2
Schwarz, K.3
-
3
-
-
33749130614
-
Three memory subsets of human CD8+ T-cells differently expressing three cytolytic effector molecules
-
Takata H, Takiguchi M. Three memory subsets of human CD8+ T-cells differently expressing three cytolytic effector molecules. J Immunol 2006; 177(7): 4330-4340.
-
(2006)
J Immunol
, vol.177
, Issue.7
, pp. 4330-4340
-
-
Takata, H.1
Takiguchi, M.2
-
4
-
-
20344397363
-
Peripheral generation and function of CD4+CD25+ regulatory T cells
-
Taams LS, Akbar AN. Peripheral generation and function of CD4+CD25+ regulatory T cells. Curr Top Microbiol Immunol 2005; 293: 115-131.
-
(2005)
Curr Top Microbiol Immunol
, vol.293
, pp. 115-131
-
-
Taams, L.S.1
Akbar, A.N.2
-
5
-
-
26244462712
-
Thymic regulatory T cells
-
Maggi E, Cosmi L, Liotta F, et al. Thymic regulatory T cells. Autoimmun Rev 2005; 4(8): 579-586.
-
(2005)
Autoimmun Rev
, vol.4
, Issue.8
, pp. 579-586
-
-
Maggi, E.1
Cosmi, L.2
Liotta, F.3
-
6
-
-
33750008921
-
Regulatory T cells and transplantation tolerance
-
Jiang S, Lechler RI, He XS, et al. Regulatory T cells and transplantation tolerance. Hum Immunol 2006; 67(10): 765-776.
-
(2006)
Hum Immunol
, vol.67
, Issue.10
, pp. 765-776
-
-
Jiang, S.1
Lechler, R.I.2
He, X.S.3
-
7
-
-
33745190990
-
CD4+CD25+ regulatory T cells in health and disease
-
Liu H, Leung BP. CD4+CD25+ regulatory T cells in health and disease. Clin Exp Pharmacol Physiol 2006; 33(5-6): 519-524.
-
(2006)
Clin Exp Pharmacol Physiol
, vol.33
, Issue.5-6
, pp. 519-524
-
-
Liu, H.1
Leung, B.P.2
-
8
-
-
34548646643
-
The regulatory effect of natural killer cells: Do “NK-reg cells” exist?
-
Zhang C, Zhang J, Tian Z. The regulatory effect of natural killer cells: do “NK-reg cells” exist? Cell Mol Immunol 2006; 3(4): 241-254.
-
(2006)
Cell Mol Immunol
, vol.3
, Issue.4
, pp. 241-254
-
-
Zhang, C.1
Zhang, J.2
Tian, Z.3
-
9
-
-
0027310569
-
The regulation of T-cell-dependent antibody formation in vitro by CD40 ligand and IL-2
-
Grabstein KH, Maliszewski CR, Shanebeck K, et al. The regulation of T-cell-dependent antibody formation in vitro by CD40 ligand and IL-2. J Immunol 1993; 150(8 Pt 1): 3141-3147.
-
(1993)
J Immunol
, vol.150
, Issue.8
, pp. 3141-3147
-
-
Grabstein, K.H.1
Maliszewski, C.R.2
Shanebeck, K.3
-
10
-
-
0033118312
-
Immunosenescence: Impact in the young as well as the old?
-
Pawelec G. Immunosenescence: impact in the young as well as the old? Mech Ageing Dev 1999; 108(1): 1-7.
-
(1999)
Mech Ageing Dev
, vol.108
, Issue.1
, pp. 1-7
-
-
Pawelec, G.1
-
11
-
-
33747034337
-
Regulation of regulatory T cells: Role of dendritic cells and toll-like receptors
-
Kabelitz D, Wesch D, Oberg HH. Regulation of regulatory T cells: role of dendritic cells and toll-like receptors. Crit Rev Immunol 2006; 26(4): 291-306.
-
(2006)
Crit Rev Immunol
, vol.26
, Issue.4
, pp. 291-306
-
-
Kabelitz, D.1
Wesch, D.2
Oberg, H.H.3
-
12
-
-
33750689486
-
Effector and regulatory events during natural killer-dendritic cell interactions
-
Moretta L, Ferlazzo G, Bottino C, et al. Effector and regulatory events during natural killer-dendritic cell interactions. Immunol Rev 2006; 214(1): 219-228.
-
(2006)
Immunol Rev
, vol.214
, Issue.1
, pp. 219-228
-
-
Moretta, L.1
Ferlazzo, G.2
Bottino, C.3
-
13
-
-
0030925868
-
Th1/Th2 changes in aging
-
Shearer GM. Th1/Th2 changes in aging. Mech Ageing Dev 1997; 94(1-3): 1-5.
-
(1997)
Mech Ageing Dev
, vol.94
, Issue.1-3
, pp. 1-5
-
-
Shearer, G.M.1
-
14
-
-
0030889678
-
Cytometric analysis of immunosenescence
-
Cossarizza A, Ortolani C, Monti D, et al. Cytometric analysis of immunosenescence. Cytometry 1997; 27(4): 297-313.
-
(1997)
Cytometry
, vol.27
, Issue.4
, pp. 297-313
-
-
Cossarizza, A.1
Ortolani, C.2
Monti, D.3
-
15
-
-
0030894924
-
HLA phenotypes in healthy aged subjects
-
Papasteriades C, Boki K, Pappa H, et al. HLA phenotypes in healthy aged subjects. Gerontology 1997; 43(3): 176-181.
-
(1997)
Gerontology
, vol.43
, Issue.3
, pp. 176-181
-
-
Papasteriades, C.1
Boki, K.2
Pappa, H.3
-
17
-
-
0022508366
-
Absolute peripheral blood lymphocyte count and subsequent mortality of elderly men
-
Bender BS, Nagel JE, Adler WH, et al. Absolute peripheral blood lymphocyte count and subsequent mortality of elderly men. J Am Geriatr Soc 1986; 34(9): 649-654.
-
(1986)
J Am Geriatr Soc
, vol.34
, Issue.9
, pp. 649-654
-
-
Bender, B.S.1
Nagel, J.E.2
Adler, W.H.3
-
18
-
-
33751527236
-
Immunity and ageing in man
-
Pawelec G. Immunity and ageing in man. Exp Gerontol 2006; 41(12): 1239-1242.
-
(2006)
Exp Gerontol
, vol.41
, Issue.12
, pp. 1239-1242
-
-
Pawelec, G.1
-
19
-
-
0033951533
-
NK and NK/T cells in human senescence
-
Solana R, Mariani E. NK and NK/T cells in human senescence. Vaccine 2000; 18(16): 1613-1620.
-
(2000)
Vaccine
, vol.18
, Issue.16
, pp. 1613-1620
-
-
Solana, R.1
Mariani, E.2
-
20
-
-
0028891555
-
The immunology of exceptional individuals: The lesson of centenarians
-
Franceschi C, Monti D, Sansoni P, et al. The immunology of exceptional individuals: the lesson of centenarians. Immunol Today 1995; 16(11): 549-550.
-
(1995)
Immunol Today
, vol.16
, Issue.11
, pp. 549-550
-
-
Franceschi, C.1
Monti, D.2
Sansoni, P.3
-
21
-
-
0032951779
-
A perspective on cellular immunity in the elderly
-
Khanna KV, Markham RB. A perspective on cellular immunity in the elderly. Clin Infect Dis 1999; 28(4): 710-735.
-
(1999)
Clin Infect Dis
, vol.28
, Issue.4
, pp. 710-735
-
-
Khanna, K.V.1
Markham, R.B.2
-
22
-
-
0025336034
-
Necessity of the assessment of health status in human immunogerontological studies: Evaluation of the SENIEUR protocol
-
Ligthart GJ, Corberand JX, Geertzen HG, et al. Necessity of the assessment of health status in human immunogerontological studies: evaluation of the SENIEUR protocol. Mech Ageing Dev 1990; 55(1): 89-105.
-
(1990)
Mech Ageing Dev
, vol.55
, Issue.1
, pp. 89-105
-
-
Ligthart, G.J.1
Corberand, J.X.2
Geertzen, H.G.3
-
23
-
-
0032921202
-
Antigen presentation in the immune response to infectious diseases
-
Pamer EG. Antigen presentation in the immune response to infectious diseases. Clin Infect Dis 1999; 28(4): 714-716.
-
(1999)
Clin Infect Dis
, vol.28
, Issue.4
, pp. 714-716
-
-
Pamer, E.G.1
-
24
-
-
0032752273
-
Biomarkers of immunosenescence: The challenge of heterogeneity and the role of antigenic load
-
Franceschi C, Valensin S, Fagnoni F, et al. Biomarkers of immunosenescence: the challenge of heterogeneity and the role of antigenic load. Exp Gerontol 1999; 34(8): 911-921.
-
(1999)
Exp Gerontol
, vol.34
, Issue.8
, pp. 911-921
-
-
Franceschi, C.1
Valensin, S.2
Fagnoni, F.3
-
25
-
-
16344376370
-
Inflamm-ageing and lifelong antigenic load as major determinants of ageing rate and longevity
-
De Martinis M, Franceschi C, Monti D, et al. Inflamm-ageing and lifelong antigenic load as major determinants of ageing rate and longevity. FEBS Lett 2005; 579(10): 2035-2039.
-
(2005)
FEBS Lett
, vol.579
, Issue.10
, pp. 2035-2039
-
-
De Martinis, M.1
Franceschi, C.2
Monti, D.3
-
27
-
-
0035014855
-
Changes in the expression of surface receptors on lymphocyte subsets in the elderly: A quantitative flow cytometric analysis
-
Ginaldi L, De Martinis M, D’Ostilio A, et al. Changes in the expression of surface receptors on lymphocyte subsets in the elderly: a quantitative flow cytometric analysis. Am J Hematol 2001; 67(2): 63-72.
-
(2001)
Am J Hematol
, vol.67
, Issue.2
, pp. 63-72
-
-
Ginaldi, L.1
De Martinis, M.2
D’Ostilio, A.3
-
28
-
-
0029890795
-
Differential expression of CD3 and CD7 in T-cell malignancies. A quantitative study by flow cytometry
-
Ginaldi L, Matutes E, Farahat U, et al. Differential expression of CD3 and CD7 in T-cell malignancies. A quantitative study by flow cytometry. Br J Haematol 1996; 93(4): 921-927.
-
(1996)
Br J Haematol
, vol.93
, Issue.4
, pp. 921-927
-
-
Ginaldi, L.1
Matutes, E.2
Farahat, U.3
-
29
-
-
0031837813
-
Levels of expression of CD19 and CD20 in chronic B-lineage leukaemias
-
Ginaldi L, De Martinis M, Matutes E, et al. Levels of expression of CD19 and CD20 in chronic B-lineage leukaemias. J Clin Pathol 1998; 51(5): 364-369.
-
(1998)
J Clin Pathol
, vol.51
, Issue.5
, pp. 364-369
-
-
Ginaldi, L.1
De Martinis, M.2
Matutes, E.3
-
30
-
-
0034555131
-
Adhesion molecules on peripheral blood lymphocyte subpopulations in the elderly
-
De Martinis M, Modesti M, Loreto MF, et al. Adhesion molecules on peripheral blood lymphocyte subpopulations in the elderly. Life Sci 2000; 68(2): 139-151.
-
(2000)
Life Sci
, vol.68
, Issue.2
, pp. 139-151
-
-
De Martinis, M.1
Modesti, M.2
Loreto, M.F.3
-
31
-
-
0033798392
-
Immunophenotypical changes of T-lymphocytes in the elderly
-
Ginaldi L, De Martinis M, Modesti M, et al. Immunophenotypical changes of T-lymphocytes in the elderly. Gerontology 2000; 46(5): 242-248.
-
(2000)
Gerontology
, vol.46
, Issue.5
, pp. 242-248
-
-
Ginaldi, L.1
De Martinis, M.2
Modesti, M.3
-
32
-
-
0032696553
-
The immune system in the elderly. III. Innate immunity
-
Ginaldi L, De Martinis M, D’Ostilio A, et al. The immune system in the elderly. III. Innate immunity. Immunol Res 1999; 20(2): 117-126.
-
(1999)
Immunol Res
, vol.20
, Issue.2
, pp. 117-126
-
-
Ginaldi, L.1
De Martinis, M.2
D’Ostilio, A.3
-
33
-
-
0031463643
-
Cell death and longevity: Implications of Fas-mediated apoptosis in T-cell senescence
-
Mountz JD, Wu J, Jzhou T, et al. Cell death and longevity: implications of Fas-mediated apoptosis in T-cell senescence. Immunol Rev 1997; 160: 19-30.
-
(1997)
Immunol Rev
, vol.160
, pp. 19-30
-
-
Mountz, J.D.1
Wu, J.2
Jzhou, T.3
-
34
-
-
0031451795
-
From naïve to effector- alterations with aging
-
Linton PJ, Haynes L, Tsui L, et al. From naïve to effector- alterations with aging. Immunol Rev 1997; 160: 9-18.
-
(1997)
Immunol Rev
, vol.160
, pp. 9-18
-
-
Linton, P.J.1
Haynes, L.2
Tsui, L.3
-
35
-
-
10744223612
-
Marked increase with age of type 1 cytokines within memory and effector/cytotoxic CD8+ T cells in humans: A contribution to understand the relationship between inflammation and immunosenescence
-
Zanni F, Vescovini R, Biasini C, et al. Marked increase with age of type 1 cytokines within memory and effector/cytotoxic CD8+ T cells in humans: a contribution to understand the relationship between inflammation and immunosenescence. Exp Gerontol 2003; 38(9): 981-987.
-
(2003)
Exp Gerontol
, vol.38
, Issue.9
, pp. 981-987
-
-
Zanni, F.1
Vescovini, R.2
Biasini, C.3
-
36
-
-
33646550890
-
Age-dependent modifications of Type 1 and Type 2 cytokines within virgin and memory CD4+ Tcells in humans
-
Alberti S, Cevenini E, Ostan R, et al. Age-dependent modifications of Type 1 and Type 2 cytokines within virgin and memory CD4+ Tcells in humans. Mech Ageing Dev 2006; 127(6): 560-566.
-
(2006)
Mech Ageing Dev
, vol.127
, Issue.6
, pp. 560-566
-
-
Alberti, S.1
Cevenini, E.2
Ostan, R.3
-
37
-
-
0033911488
-
Inflamm-aging. An evolutionary perspective on immunosenescence
-
Franceschi C, Bonafe M, Valensin S, et al. Inflamm-aging. An evolutionary perspective on immunosenescence. Ann NY Acad Sci 2000; 908: 244-254.
-
(2000)
Ann NY Acad Sci
, vol.908
, pp. 244-254
-
-
Franceschi, C.1
Bonafe, M.2
Valensin, S.3
-
38
-
-
33845222777
-
Innate immunita and inflammation in ageing: A key for understanding age-related diseases
-
Licastro F, Candore G, Lio D, et al. Innate immunita and inflammation in ageing: a key for understanding age-related diseases. Immun Ageing 2005; 2: 8-27.
-
(2005)
Immun Ageing
, vol.2
, pp. 8-27
-
-
Licastro, F.1
Candore, G.2
Lio, D.3
-
39
-
-
0026005830
-
Detectable serum levels of tumor necrosis factor alpha may predict early mortality in elderly institutionalized patients
-
Mooradian AD, Reed RL, Osterweil D, et al. Detectable serum levels of tumor necrosis factor alpha may predict early mortality in elderly institutionalized patients. Am Geriatr Soc 1991; 39(9): 891-894.
-
(1991)
Am Geriatr Soc
, vol.39
, Issue.9
, pp. 891-894
-
-
Mooradian, A.D.1
Reed, R.L.2
Osterweil, D.3
-
40
-
-
0141892842
-
Cytokines, insulin-like growth factor 1, sarcopenia, and mortality in very old community- dwelling men and women: The Framingham Heart Study
-
Roubenoff R, Parise H, Payette HA, et al. Cytokines, insulin-like growth factor 1, sarcopenia, and mortality in very old community- dwelling men and women: the Framingham Heart Study. Am J Med 2003; 115(6): 429-435.
-
(2003)
Am J Med
, vol.115
, Issue.6
, pp. 429-435
-
-
Roubenoff, R.1
Parise, H.2
Payette, H.A.3
-
41
-
-
0038369150
-
Insulin-like growth factor I and interleukin-6 contribute synergistically to disability and mortality in older women
-
Cappola AR, Xue QL, Ferrucci L, et al. Insulin-like growth factor I and interleukin-6 contribute synergistically to disability and mortality in older women. J Clin Endocrinol Metab 2003; 88(5): 2019-2025.
-
(2003)
J Clin Endocrinol Metab
, vol.88
, Issue.5
, pp. 2019-2025
-
-
Cappola, A.R.1
Xue, Q.L.2
Ferrucci, L.3
-
42
-
-
0033975581
-
Human immunosenescence: The prevailing of innate immunity, the failing of clonotypic immunity, and the filling of immunological space
-
Franceschi C, Bonafe M, Valensin S. Human immunosenescence: the prevailing of innate immunity, the failing of clonotypic immunity, and the filling of immunological space. Vaccine 2000; 18(16): 1717-1720.
-
(2000)
Vaccine
, vol.18
, Issue.16
, pp. 1717-1720
-
-
Franceschi, C.1
Bonafe, M.2
Valensin, S.3
-
44
-
-
33751106906
-
Senile osteoporosis: Is it an immune-mediated disease?
-
De Martinis M, Di Benedetto MC, Mengoli LP, et al. Senile osteoporosis: is it an immune-mediated disease? Inflamm Res 2006; 55(10): 399-404.
-
(2006)
Inflamm Res
, vol.55
, Issue.10
, pp. 399-404
-
-
De Martinis, M.1
Di Benedetto, M.C.2
Mengoli, L.P.3
-
45
-
-
33646518593
-
Inflammation markers predicting frailty and mortality in the elderly
-
De Martinis M, Franceschi C, Monti D, et al. Inflammation markers predicting frailty and mortality in the elderly. Exp Mol Pathol 2006; 80(3): 219-227.
-
(2006)
Exp Mol Pathol
, vol.80
, Issue.3
, pp. 219-227
-
-
De Martinis, M.1
Franceschi, C.2
Monti, D.3
-
47
-
-
23344444980
-
Inflammation and Coronary heart disease
-
Tiong AY, Brieger D. Inflammation and Coronary heart disease. Am Heart J 2005; 150(1): 11-18.
-
(2005)
Am Heart J
, vol.150
, Issue.1
, pp. 11-18
-
-
Tiong, A.Y.1
Brieger, D.2
-
48
-
-
17144369225
-
Macrophage conditioned medium induces the expression of C-reactive protein in human aortic endothelial cells (potential for paracrine/autocrine effects)
-
Venugopal SK, Devaraj S, Jialal I. Macrophage conditioned medium induces the expression of C-reactive protein in human aortic endothelial cells (potential for paracrine/autocrine effects). Am J Pathol 2005; 166(4): 1265-1271.
-
(2005)
Am J Pathol
, vol.166
, Issue.4
, pp. 1265-1271
-
-
Venugopal, S.K.1
Devaraj, S.2
Jialal, I.3
-
49
-
-
0029966724
-
Stage specific alterations in murine B-lymphopoiesis with age
-
Stephan RP, Sanders VM, Witte PL. Stage specific alterations in murine B-lymphopoiesis with age. Int Immunol 1996; 8(4): 509-518.
-
(1996)
Int Immunol
, vol.8
, Issue.4
, pp. 509-518
-
-
Stephan, R.P.1
Sanders, V.M.2
Witte, P.L.3
-
50
-
-
0031448877
-
The B-cell biology of aging
-
Klinman NR, Kline GH. The B-cell biology of aging. Immunol Rev 1997; 160: 103-114.
-
(1997)
Immunol Rev
, vol.160
, pp. 103-114
-
-
Klinman, N.R.1
Kline, G.H.2
-
51
-
-
0032523315
-
Molecular and cellular basis of immunosenescence
-
Solana R, Pawelec G. Molecular and cellular basis of immunosenescence. Mech Ageing Dev 1998; 102(2-3): 115-129.
-
(1998)
Mech Ageing Dev
, vol.102
, Issue.2-3
, pp. 115-129
-
-
Solana, R.1
Pawelec, G.2
-
52
-
-
23044485184
-
Immune receptor signaling, aging, and autoimmunity
-
Hasler P, Zouali M. Immune receptor signaling, aging, and autoimmunity. Cell Immunol 2005; 233(2): 102-108.
-
(2005)
Cell Immunol
, vol.233
, Issue.2
, pp. 102-108
-
-
Hasler, P.1
Zouali, M.2
-
53
-
-
4444320808
-
Senescence of the B Cell Compartment: Implication for humoral immunity
-
Johnson SA, Cambier JC. Senescence of the B Cell Compartment: implication for humoral immunity. Arthritis Res Ther 2004; 6(4): 131-139.
-
(2004)
Arthritis Res Ther
, vol.6
, Issue.4
, pp. 131-139
-
-
Johnson, S.A.1
Cambier, J.C.2
-
54
-
-
0031435618
-
Age-related changes in antibody repertoire: Contribution from T cells
-
Song H, Price PW, Cerny J. Age-related changes in antibody repertoire: contribution from T cells. Immunol Rev 1997; 160: 55-62.
-
(1997)
Immunol Rev
, vol.160
, pp. 55-62
-
-
Song, H.1
Price, P.W.2
Cerny, J.3
-
55
-
-
0032716683
-
The immune system in the elderly. I. Specific humoral immunity
-
Ginaldi L, De Martinis M, D’Ostilio A, et al. The immune system in the elderly. I. Specific humoral immunity. Immunol Res 1999; 20(2): 109-115.
-
(1999)
Immunol Res
, vol.20
, Issue.2
, pp. 109-115
-
-
Ginaldi, L.1
De Martinis, M.2
D’Ostilio, A.3
-
56
-
-
0343750697
-
Impaired germinal center reaction in mice with short telomeres
-
Herrera E, Martinez AC, Blasco MA. Impaired germinal center reaction in mice with short telomeres. EMBO J 2000; 19(3): 472-481.
-
(2000)
EMBO J
, vol.19
, Issue.3
, pp. 472-481
-
-
Herrera, E.1
Martinez, A.C.2
Blasco, M.A.3
-
58
-
-
0032718159
-
The immune system in the elderly. II. Specific cellular immunity
-
Ginaldi L, De Martinis M, D’Ostilio A, et al. The immune system in the elderly. II. Specific cellular immunity. Immunol Res 1999; 20(2): 109-115.
-
(1999)
Immunol Res
, vol.20
, Issue.2
, pp. 109-115
-
-
Ginaldi, L.1
De Martinis, M.2
D’Ostilio, A.3
-
60
-
-
0034194058
-
Shortage of circulating naïve CD8+ T cells provides new insights on immunodeficiency in aging
-
Fagnoni FF, Vescovini R, Passeri G, et al. Shortage of circulating naïve CD8+ T cells provides new insights on immunodeficiency in aging. Blood 2000; 95(9): 2860-2868.
-
(2000)
Blood
, vol.95
, Issue.9
, pp. 2860-2868
-
-
Fagnoni, F.F.1
Vescovini, R.2
Passeri, G.3
-
61
-
-
0031137735
-
Expanded CD4+ and CD8+ T-cell clones in elderly humans
-
Schwab R, Skabo P, Manavalan JS, et al. Expanded CD4+ and CD8+ T-cell clones in elderly humans. J Immunol 1997; 158(9): 4493-4499.
-
(1997)
J Immunol
, vol.158
, Issue.9
, pp. 4493-4499
-
-
Schwab, R.1
Skabo, P.2
Manavalan, J.S.3
-
62
-
-
18844476795
-
Early lymphocyte activation in elderly humans: Impaired T and T-dependent B-cell responses
-
Fernandez-Gutierrez B, Jover JAA, De Miguel S, et al. Early lymphocyte activation in elderly humans: impaired T and T-dependent B-cell responses. Exp Gerontol 1999; 34(2): 217-229.
-
(1999)
Exp Gerontol
, vol.34
, Issue.2
, pp. 217-229
-
-
Fernandez-Gutierrez, B.1
Jover, J.A.A.2
De Miguel, S.3
-
63
-
-
23044433753
-
Homeostasis and the ageassociated defect of CD4 T cells
-
Swain S, Clise-Dwyer K, Haynes L. Homeostasis and the ageassociated defect of CD4 T cells. Semin Immunol 2005; 17(5): 370-377.
-
(2005)
Semin Immunol
, vol.17
, Issue.5
, pp. 370-377
-
-
Swain, S.1
Clise-Dwyer, K.2
Haynes, L.3
-
64
-
-
0029826636
-
Antigen-independent changes in naïve CD4 T cells with aging
-
Linton PJ, Haynes L, Klinman NR, et al. Antigen-independent changes in naïve CD4 T cells with aging. J Exp Med 1996; 184(5): 1891-1900.
-
(1996)
J Exp Med
, vol.184
, Issue.5
, pp. 1891-1900
-
-
Linton, P.J.1
Haynes, L.2
Klinman, N.R.3
-
65
-
-
24044463890
-
Dysregulation of T-cell function in the elderly: Scientific basis and clinical implications
-
Fulop T, Larbi A, Wikby A, et al. Dysregulation of T-cell function in the elderly: scientific basis and clinical implications. Drugs Aging 2005; 22(7): 589-603.
-
(2005)
Drugs Aging
, vol.22
, Issue.7
, pp. 589-603
-
-
Fulop, T.1
Larbi, A.2
Wikby, A.3
-
66
-
-
0141481855
-
Functional assay for human CD4+CD25+ Treg cells reveals an age-dependent loss of suppressive activity
-
Tsakanaridis L, Spencer L, Culbertson N, et al. Functional assay for human CD4+CD25+ Treg cells reveals an age-dependent loss of suppressive activity. J Neurosci Res 2003; 74(2): 296-308.
-
(2003)
J Neurosci Res
, vol.74
, Issue.2
, pp. 296-308
-
-
Tsakanaridis, L.1
Spencer, L.2
Culbertson, N.3
-
67
-
-
20444396226
-
Thymic commitment of regulatory T cells is a pathway of TCR-dependent selection that isolates repertoires undergoing positive or negative selection
-
Coutinho A, Caramalho I, Seixas E, et al. Thymic commitment of regulatory T cells is a pathway of TCR-dependent selection that isolates repertoires undergoing positive or negative selection. Curr Top Microbiol Immunol 2005; 293: 43-71.
-
(2005)
Curr Top Microbiol Immunol
, vol.293
, pp. 43-71
-
-
Coutinho, A.1
Caramalho, I.2
Seixas, E.3
-
68
-
-
0033015824
-
T-cell immunosenescence in vitro and in vivo
-
Pawelec G, Wagner V, Adibzadeh M, et al. T-cell immunosenescence in vitro and in vivo. Exp Gerontol 1999; 34(3): 419-429.
-
(1999)
Exp Gerontol
, vol.34
, Issue.3
, pp. 419-429
-
-
Pawelec, G.1
Wagner, V.2
Adibzadeh, M.3
-
70
-
-
0033555960
-
Maturation of CD4+ lymphocytes in the aged microenvironment results in a memory-enriched population
-
Timm JA, Thoman ML. Maturation of CD4+ lymphocytes in the aged microenvironment results in a memory-enriched population. J Immunol 1999; 162(2): 711-717.
-
(1999)
J Immunol
, vol.162
, Issue.2
, pp. 711-717
-
-
Timm, J.A.1
Thoman, M.L.2
-
71
-
-
23944441502
-
T-cell development and receptor diversity during aging
-
Goronzy JJ, Weyand CM. T-cell development and receptor diversity during aging. Curr Opin Immunol 2005; 17(5): 468-475.
-
(2005)
Curr Opin Immunol
, vol.17
, Issue.5
, pp. 468-475
-
-
Goronzy, J.J.1
Weyand, C.M.2
-
72
-
-
0033977119
-
Costimulatory mechanisms in the elderly
-
Effros RB. Costimulatory mechanisms in the elderly. Vaccine 2000; 18(16): 1661-1665.
-
(2000)
Vaccine
, vol.18
, Issue.16
, pp. 1661-1665
-
-
Effros, R.B.1
-
73
-
-
0031788815
-
Extrathymic T-cell differentiation in vitro from human CD34+ stem cells
-
Pawelec G, Muller P, Rehbein A, et al. Extrathymic T-cell differentiation in vitro from human CD34+ stem cells. J Leukoc Biol 1998; 64(6): 733-739.
-
(1998)
J Leukoc Biol
, vol.64
, Issue.6
, pp. 733-739
-
-
Pawelec, G.1
Muller, P.2
Rehbein, A.3
-
74
-
-
0033951594
-
Evidence for thymic function in the elderly
-
Douek DC, Koup RA. Evidence for thymic function in the elderly. Vaccine 2000; 18(16): 1638-1641.
-
(2000)
Vaccine
, vol.18
, Issue.16
, pp. 1638-1641
-
-
Douek, D.C.1
Koup, R.A.2
-
75
-
-
0034636053
-
Identification of a human recent thymic emigrant phenotype
-
McFarland R, Dowek DC, Koud RA, et al. Identification of a human recent thymic emigrant phenotype. Proc Natl Acad Sci 2000; 97(8): 4215-4220.
-
(2000)
Proc Natl Acad Sci
, vol.97
, Issue.8
, pp. 4215-4220
-
-
McFarland, R.1
Dowek, D.C.2
Koud, R.A.3
-
76
-
-
0031960827
-
Replicative senescence in the immune system: Impact of the Hayflick limit on T-cell function in the elderly
-
Effros RB. Replicative senescence in the immune system: impact of the Hayflick limit on T-cell function in the elderly. Am J Hum Gen 1998; 62(5): 1003-1007.
-
(1998)
Am J Hum Gen
, vol.62
, Issue.5
, pp. 1003-1007
-
-
Effros, R.B.1
-
77
-
-
0037825764
-
Large numbers of dysfunctional CD8+ T-lymphocytes bearing receptors for a single dominant CMVepitope in the very old
-
Ouyang Q, Wagner WM, Wikby A, et al. Large numbers of dysfunctional CD8+ T-lymphocytes bearing receptors for a single dominant CMVepitope in the very old. J Clin Immunol 2003; 23(4): 247-257.
-
(2003)
J Clin Immunol
, vol.23
, Issue.4
, pp. 247-257
-
-
Ouyang, Q.1
Wagner, W.M.2
Wikby, A.3
-
78
-
-
20444497416
-
The number of human peripheral blood CD4+ CD25high regulatory T cells increases with age
-
Koch GR, Smith CM, Clark FJ, et al. The number of human peripheral blood CD4+ CD25high regulatory T cells increases with age. Clin Exp Immunol 2005; 140(3): 540-546.
-
(2005)
Clin Exp Immunol
, vol.140
, Issue.3
, pp. 540-546
-
-
Koch, G.R.1
Smith, C.M.2
Clark, F.J.3
-
79
-
-
0030667714
-
Altered lymphocyte antigen expressions in HIV infection: A study by quantitative flow cytometry
-
Ginaldi L, De Martinis M, D’Ostilio A, et al. Altered lymphocyte antigen expressions in HIV infection: a study by quantitative flow cytometry. Am J Clin Pathol 1997; 108(5): 585-592.
-
(1997)
Am J Clin Pathol
, vol.108
, Issue.5
, pp. 585-592
-
-
Ginaldi, L.1
De Martinis, M.2
D’Ostilio, A.3
-
80
-
-
0031888294
-
Changes in antigen expressions on B-lymphocytes during HIV infection
-
Ginaldi L, De Martinis M, D’Ostilio A, et al. Changes in antigen expressions on B-lymphocytes during HIV infection. Pathobiology 1998; 66(1): 17-23.
-
(1998)
Pathobiology
, vol.66
, Issue.1
, pp. 17-23
-
-
Ginaldi, L.1
De Martinis, M.2
D’Ostilio, A.3
-
81
-
-
0034107028
-
Accelerated replicative senescence of the peripheral immune system induced by HIV infection
-
Bestilny LJ, Gill MJ, Mody CH, et al. Accelerated replicative senescence of the peripheral immune system induced by HIV infection. AIDS 2000; 14(7): 771-780.
-
(2000)
AIDS
, vol.14
, Issue.7
, pp. 771-780
-
-
Bestilny, L.J.1
Gill, M.J.2
Mody, C.H.3
-
82
-
-
0034458563
-
Clinical relevance of age related immune dysfunction
-
Castle SC. Clinical relevance of age related immune dysfunction. Clin Infect Dis 2000; 31(2): 578-585.
-
(2000)
Clin Infect Dis
, vol.31
, Issue.2
, pp. 578-585
-
-
Castle, S.C.1
-
83
-
-
0030925869
-
Cytokines and impaired CD8+ CTL activity among elderly persons and the enhancing effect of IL-12
-
Mbawuike IN, Acuna CL, Walz KC, et al. Cytokines and impaired CD8+ CTL activity among elderly persons and the enhancing effect of IL-12. Mech Ageing Dev 1997; 94(1-3): 25-39.
-
(1997)
Mech Ageing Dev
, vol.94
, Issue.1-3
, pp. 25-39
-
-
Mbawuike, I.N.1
Acuna, C.L.2
Walz, K.C.3
-
84
-
-
0031001178
-
Senescence and cytokines modulate the NK cell expression
-
Krishnaraj R. Senescence and cytokines modulate the NK cell expression. Mech Ageing Dev 1997; 96(1-3): 89-101.
-
(1997)
Mech Ageing Dev
, vol.96
, Issue.1-3
, pp. 89-101
-
-
Krishnaraj, R.1
-
85
-
-
0028122472
-
Age-related changes in immune parameters in a very old population of Swedish people: A longitudinal study
-
Wikby A, Johansson B, Ferguson F, et al. Age-related changes in immune parameters in a very old population of Swedish people: a longitudinal study. Exp Gerontol 1994; 29(5): 531-541.
-
(1994)
Exp Gerontol
, vol.29
, Issue.5
, pp. 531-541
-
-
Wikby, A.1
Johansson, B.2
Ferguson, F.3
-
86
-
-
0033026570
-
NK phenotypic markers and IL-2 response in NK cells from elderly people
-
Borrego F, Alonso ML, Galiani MD, et al. NK phenotypic markers and IL-2 response in NK cells from elderly people. Exp Gerontol 1999; 34(2): 253-265.
-
(1999)
Exp Gerontol
, vol.34
, Issue.2
, pp. 253-265
-
-
Borrego, F.1
Alonso, M.L.2
Galiani, M.D.3
-
87
-
-
0032189078
-
Age-related decline of perforin expression in human cytotoxic T-lymphocytes and natural killer cells
-
Rukavina D, Laskarin G, Rubesa G, et al. Age-related decline of perforin expression in human cytotoxic T-lymphocytes and natural killer cells. Blood 1998; 92(7): 2410-2420.
-
(1998)
Blood
, vol.92
, Issue.7
, pp. 2410-2420
-
-
Rukavina, D.1
Laskarin, G.2
Rubesa, G.3
-
88
-
-
4043089285
-
CD4+CD25+ T regulatory cells inhibit cytotoxic activity of T CD8+ and NK lymphocytes in the direct cell-to-cell interaction
-
Trzonkowski P, Szmit E, Mysliwska J, et al. CD4+CD25+ T regulatory cells inhibit cytotoxic activity of T CD8+ and NK lymphocytes in the direct cell-to-cell interaction. Clin Immunol 2004; 112(3): 258-267.
-
(2004)
Clin Immunol
, vol.112
, Issue.3
, pp. 258-267
-
-
Trzonkowski, P.1
Szmit, E.2
Mysliwska, J.3
-
89
-
-
33646397029
-
CD4+ CD25+ T regulatory cells inhibit cytotoxic activity of CTL and NK cells in humans-impact of immunosenescence
-
Trzonkowski P, Szmit E, Mysliwska J, et al. CD4+ CD25+ T regulatory cells inhibit cytotoxic activity of CTL and NK cells in humans-impact of immunosenescence. Clin Immunol 2006; 119(3): 307-316.
-
(2006)
Clin Immunol
, vol.119
, Issue.3
, pp. 307-316
-
-
Trzonkowski, P.1
Szmit, E.2
Mysliwska, J.3
-
90
-
-
0032707321
-
Impaired production of proinflammatory cytokines in response to lipopolysaccharide (LPS) stimulation in elderly humans
-
Bruunsgaard H, Pedersen AN, Schroll M, et al. Impaired production of proinflammatory cytokines in response to lipopolysaccharide (LPS) stimulation in elderly humans. Clin Exp Immunol 1999; 118(2): 235-241.
-
(1999)
Clin Exp Immunol
, vol.118
, Issue.2
, pp. 235-241
-
-
Bruunsgaard, H.1
Pedersen, A.N.2
Schroll, M.3
-
91
-
-
4344658758
-
Phenotypic and functional changes of circulating monocytes and polymorphonuclear leucocytes from elderly persons
-
De Martinis M, Modesti M, Ginaldi L. Phenotypic and functional changes of circulating monocytes and polymorphonuclear leucocytes from elderly persons. Immunol Cell Biol 2004; 82(4): 415-420.
-
(2004)
Immunol Cell Biol
, vol.82
, Issue.4
, pp. 415-420
-
-
De Martinis, M.1
Modesti, M.2
Ginaldi, L.3
-
92
-
-
0029880359
-
Neutrophil function in elderly persons assessed by flow cytometry
-
Esparza B, Sanchez H, Ruiz M, et al. Neutrophil function in elderly persons assessed by flow cytometry. Immunol Invest 1996; 25(3): 185-190.
-
(1996)
Immunol Invest
, vol.25
, Issue.3
, pp. 185-190
-
-
Esparza, B.1
Sanchez, H.2
Ruiz, M.3
-
93
-
-
0032880206
-
Effect of aging on CD11b and CD69 surface expression by vesicular insertion in human polymorphonuclear leucocytes
-
Noble JM, Ford GA, Thomas TH. Effect of aging on CD11b and CD69 surface expression by vesicular insertion in human polymorphonuclear leucocytes. Clin Sci 1999; 97(3): 323-329.
-
(1999)
Clin Sci
, vol.97
, Issue.3
, pp. 323-329
-
-
Noble, J.M.1
Ford, G.A.2
Thomas, T.H.3
-
94
-
-
0032401926
-
Similar responses by macrophages from young and old mice infected with mycobacterium tuberculosis
-
Rhoades ER, Orme IM. Similar responses by macrophages from young and old mice infected with mycobacterium tuberculosis. Mech Ageing Dev 1998; 106(1-2): 145-153.
-
(1998)
Mech Ageing Dev
, vol.106
, Issue.1-2
, pp. 145-153
-
-
Rhoades, E.R.1
Orme, I.M.2
-
95
-
-
0032722001
-
Phenotypic and functional characteristics of circulating monocytes of elderly persons
-
Sadeghi HM, Schnelle JF, Thoma JK, et al. Phenotypic and functional characteristics of circulating monocytes of elderly persons. Exp Gerontol 1999; 34(8): 959-970.
-
(1999)
Exp Gerontol
, vol.34
, Issue.8
, pp. 959-970
-
-
Sadeghi, H.M.1
Schnelle, J.F.2
Thoma, J.K.3
-
96
-
-
3342981630
-
Systemic autoimmune diseases in elderly patients: Atypical presentation and association with neoplasia
-
Ramos-Casals M, Brito-Zeron P, Lopez-Soto A, et al. Systemic autoimmune diseases in elderly patients: atypical presentation and association with neoplasia. Autoimmun Rev 2004; 3(5): 376-382.
-
(2004)
Autoimmun Rev
, vol.3
, Issue.5
, pp. 376-382
-
-
Ramos-Casals, M.1
Brito-Zeron, P.2
Lopez-Soto, A.3
-
97
-
-
0037198040
-
Immunological memory and late onset autoimmunity
-
Stacy S, Krolick KA, Infante AJ, et al. Immunological memory and late onset autoimmunity. Mech Ageing Dev 2002; 123(8): 975-985.
-
(2002)
Mech Ageing Dev
, vol.123
, Issue.8
, pp. 975-985
-
-
Stacy, S.1
Krolick, K.A.2
Infante, A.J.3
-
98
-
-
0043125779
-
Immunosenescence, autoimmunity, and rheumatoid arthritis
-
Weyand CM, Fulbright JW, Goronzy JJ. Immunosenescence, autoimmunity, and rheumatoid arthritis. Exp Gerontol 2003; 38(8): 833-841.
-
(2003)
Exp Gerontol
, vol.38
, Issue.8
, pp. 833-841
-
-
Weyand, C.M.1
Fulbright, J.W.2
Goronzy, J.J.3
-
99
-
-
2942733256
-
Human CD25+ regulatory Tcells: Two subsets defined by the integrins alpha 4 beta 7 or alpha 4 beta 1 confer distinct suppressive properties upon CD4+ T helper cells
-
Stassen M, Fondel S, Bopp T, et al. Human CD25+ regulatory Tcells: two subsets defined by the integrins alpha 4 beta 7 or alpha 4 beta 1 confer distinct suppressive properties upon CD4+ T helper cells. Eur J Immunol 2004; 34(5): 1303-1311.
-
(2004)
Eur J Immunol
, vol.34
, Issue.5
, pp. 1303-1311
-
-
Stassen, M.1
Fondel, S.2
Bopp, T.3
-
100
-
-
0345420668
-
Cell proliferation and apoptosis in the immune system in the elderly
-
Ginaldi L, De Martinis M, D’Ostilio A, et al. Cell proliferation and apoptosis in the immune system in the elderly. Immunol Res 2000; 21(1): 31-38.
-
(2000)
Immunol Res
, vol.21
, Issue.1
, pp. 31-38
-
-
Ginaldi, L.1
De Martinis, M.2
D’Ostilio, A.3
-
101
-
-
0030009805
-
Excessive apoptosis of mature T-lymphocytes is a characteristic feature of human immune senescence
-
Phelouzat MA, Arbogast A, Laforge T, et al. Excessive apoptosis of mature T-lymphocytes is a characteristic feature of human immune senescence. Mech Ageing Dev 1996; 88(1-2): 25-38.
-
(1996)
Mech Ageing Dev
, vol.88
, Issue.1-2
, pp. 25-38
-
-
Phelouzat, M.A.1
Arbogast, A.2
Laforge, T.3
-
102
-
-
0031011169
-
Increased apoptosis of CD45RO- T cells with aging
-
Herndon FJ, Hsu HC, Mountz JD. Increased apoptosis of CD45RO- T cells with aging. Mech Ageing Dev 1997; 94(1-3): 123-134.
-
(1997)
Mech Ageing Dev
, vol.94
, Issue.1-3
, pp. 123-134
-
-
Herndon, F.J.1
Hsu, H.C.2
Mountz, J.D.3
-
103
-
-
0031463644
-
Tales of tails: Regulation of telomere length and telomerase activity during lymphocyte development, differentiation, activation and aging
-
Weng NP, Palmer LD, Levine BL, et al. Tales of tails: regulation of telomere length and telomerase activity during lymphocyte development, differentiation, activation and aging. Immunol Rev 1997; 160: 43-54.
-
(1997)
Immunol Rev
, vol.160
, pp. 43-54
-
-
Weng, N.P.1
Palmer, L.D.2
Levine, B.L.3
-
104
-
-
0031093496
-
The DNA-dependent protein kinase (p460) is cleaved during Fas-mediated apoptosis in Jurkat cells
-
McConnell KR, Dynan WS, Hardin JA. The DNA-dependent protein kinase (p460) is cleaved during Fas-mediated apoptosis in Jurkat cells. J Immunol 1997; 158(5): 2083-2089.
-
(1997)
J Immunol
, vol.158
, Issue.5
, pp. 2083-2089
-
-
McConnell, K.R.1
Dynan, W.S.2
Hardin, J.A.3
-
105
-
-
3242891953
-
The immune system in the elderly: Activation-induced and damage-induced apoptosis
-
Ginaldi L, De Martinis M, Monti D, et al. The immune system in the elderly: activation-induced and damage-induced apoptosis. Immunol Res 2004; 30(1): 81-94.
-
(2004)
Immunol Res
, vol.30
, Issue.1
, pp. 81-94
-
-
Ginaldi, L.1
De Martinis, M.2
Monti, D.3
-
106
-
-
12744253311
-
Chronic antigenic load and apoptosis in immunosenescence
-
Ginaldi L, De Martinis M, Monti D, et al. Chronic antigenic load and apoptosis in immunosenescence. Trends Immunol 2005; 26(2): 79-84.
-
(2005)
Trends Immunol
, vol.26
, Issue.2
, pp. 79-84
-
-
Ginaldi, L.1
De Martinis, M.2
Monti, D.3
-
107
-
-
33745075615
-
A paradox of immunodeficiency and inflammation in human aging: Lessons learned from apoptosis
-
Gupta S, Agrawal A, Agrawal S, et al. A paradox of immunodeficiency and inflammation in human aging: lessons learned from apoptosis. Immun Ageing 2006; 19: 3-5.
-
(2006)
Immun Ageing
, vol.19
, pp. 3-5
-
-
Gupta, S.1
Agrawal, A.2
Agrawal, S.3
-
108
-
-
0032946904
-
Micronutrient supplementation and immune function in the elderly
-
High KP. Micronutrient supplementation and immune function in the elderly. Clin Infect Dis 1999; 28(4): 717-722.
-
(1999)
Clin Infect Dis
, vol.28
, Issue.4
, pp. 717-722
-
-
High, K.P.1
-
109
-
-
3242699582
-
Influence of age and physical activity on the primary in-vivo antibody and T-cell-mediated response in men
-
Smith TP, Kennedy SL, Fleshner M. Influence of age and physical activity on the primary in-vivo antibody and T-cell-mediated response in men. J Appl Physiol 2004; 97(2): 491-498.
-
(2004)
J Appl Physiol
, vol.97
, Issue.2
, pp. 491-498
-
-
Smith, T.P.1
Kennedy, S.L.2
Fleshner, M.3
-
110
-
-
32244440985
-
The myth and reality of reversal of aging by hormesis
-
Sonneborn JS. The myth and reality of reversal of aging by hormesis. Ann N Y Acad Sci 2005; 1057: 165-176.
-
(2005)
Ann N Y Acad Sci
, vol.1057
, pp. 165-176
-
-
Sonneborn, J.S.1
-
111
-
-
0342281794
-
Relationship between the response to influenza vaccination and the nutritional status in institutionalized elderly subjects
-
Fulop T, Wagner JR, Khalil A, et al. Relationship between the response to influenza vaccination and the nutritional status in institutionalized elderly subjects. J Gerontol 1999; 54(2): M59-M64.
-
(1999)
J Gerontol
, vol.54
, Issue.2
, pp. M59-M64
-
-
Fulop, T.1
Wagner, J.R.2
Khalil, A.3
-
112
-
-
0242624574
-
Ageing, autoimmunity and arthritis: Perturbations of TCR signal transduction pathways with ageing-a biochemical paradigm for the ageing immune system
-
Fulop T Jr, Larbi A, Dupuis G, et al. Ageing, autoimmunity and arthritis: perturbations of TCR signal transduction pathways with ageing-a biochemical paradigm for the ageing immune system. Arthritis Res Ther 2003; 5(6): 290-302.
-
(2003)
Arthritis Res Ther
, vol.5
, Issue.6
, pp. 290-302
-
-
Fulop, T.1
Larbi, A.2
Dupuis, G.3
-
113
-
-
0036746072
-
Pistoresi-Palencia MC CpG-DNA stimulates cellular and humoral immunity and promotes Th1 differentiation in aged BALB/c mice
-
Maletto B, Ropolo A, Moron V. Pistoresi-Palencia MC CpG-DNA stimulates cellular and humoral immunity and promotes Th1 differentiation in aged BALB/c mice. J Leukoc Biol 2002; 72(3): 447-454.
-
(2002)
J Leukoc Biol
, vol.72
, Issue.3
, pp. 447-454
-
-
Maletto, B.1
Ropolo, A.2
Moron, V.3
-
114
-
-
0036838556
-
Defective T-cell priming associated with aging can be rescued by signaling through 4-1BB (CD137)
-
Bansal-Pakala P, Croft M. Defective T-cell priming associated with aging can be rescued by signaling through 4-1BB (CD137). J Immunol 2002; 169(9): 5005-5009.
-
(2002)
J Immunol
, vol.169
, Issue.9
, pp. 5005-5009
-
-
Bansal-Pakala, P.1
Croft, M.2
-
115
-
-
0030936949
-
Impairment of signal transduction in T cells from old mice
-
Utsuyama M, Wakikawa A, Tamura T, et al. Impairment of signal transduction in T cells from old mice. Mech Ageing Dev 1997; 93(1-3): 131-144.
-
(1997)
Mech Ageing Dev
, vol.93
, Issue.1-3
, pp. 131-144
-
-
Utsuyama, M.1
Wakikawa, A.2
Tamura, T.3
|