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Volumn 160, Issue , 1997, Pages 55-62

Age-related changes in antibody repertoire: Contribution from T cells

Author keywords

[No Author keywords available]

Indexed keywords

ACETIC ACID DERIVATIVE; ANTIBODY; CD40 ANTIGEN; HAPTEN;

EID: 0031435618     PISSN: 01052896     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-065X.1997.tb01027.x     Document Type: Review
Times cited : (92)

References (61)
  • 1
    • 0020026383 scopus 로고
    • Heterogeneity of the BALB/c IgM anti-phosphorylcholine antibody response
    • Owen JA, Sigal NH, Klinman NR. Heterogeneity of the BALB/c IgM anti-phosphorylcholine antibody response. Nature 1982;295:347-348.
    • (1982) Nature , vol.295 , pp. 347-348
    • Owen, J.A.1    Sigal, N.H.2    Klinman, N.R.3
  • 2
    • 0021016599 scopus 로고
    • Monoclonal antibodies reveal the structural basis of antibody diversity
    • Teilland J-L, et al. Monoclonal antibodies reveal the structural basis of antibody diversity. Science 1983;222:721-726.
    • (1983) Science , vol.222 , pp. 721-726
    • Teilland, J.-L.1
  • 3
    • 0023161406 scopus 로고
    • Mutation drift and repertoire shift in the maturation of the immune response
    • Berek C, Milstein C. Mutation drift and repertoire shift in the maturation of the immune response. Immunol Rev 1987;96:23-41.
    • (1987) Immunol Rev , vol.96 , pp. 23-41
    • Berek, C.1    Milstein, C.2
  • 4
    • 0023161405 scopus 로고
    • Evolution of antibody variable region structure during the immune response
    • Manser T, Wysocki LJ, Margolies MN, Gefter ML. Evolution of antibody variable region structure during the immune response. Immunol Rev 1987;96:141-162.
    • (1987) Immunol Rev , vol.96 , pp. 141-162
    • Manser, T.1    Wysocki, L.J.2    Margolies, M.N.3    Gefter, M.L.4
  • 5
    • 0021284611 scopus 로고
    • The generation of diversity in phosphorylcholine-binding antibodies
    • Perlmutter RM, et al. The generation of diversity in phosphorylcholine-binding antibodies. Adv Immunol 1984;35:1-37.
    • (1984) Adv Immunol , vol.35 , pp. 1-37
    • Perlmutter, R.M.1
  • 6
    • 0023821899 scopus 로고
    • The immune response to the hapten NP in C57BL/6 mice: Insights into the structure of the B-cell repertoire
    • Blier PR, Bothwell AL. The immune response to the hapten NP in C57BL/6 mice: insights into the structure of the B-cell repertoire. Immunol Rev 1988;105:27-43.
    • (1988) Immunol Rev , vol.105 , pp. 27-43
    • Blier, P.R.1    Bothwell, A.L.2
  • 7
    • 0025213248 scopus 로고
    • V region gene usage and somatic mutation in the primary and secondary responses to influenza virus hemagglutinin
    • Clarke SH, Staudt LM, Kavaler J, Schwartz D, Gerhard WU, Weigert MG. V region gene usage and somatic mutation in the primary and secondary responses to influenza virus hemagglutinin. J Immunol 1990;144:2795-2801.
    • (1990) J Immunol , vol.144 , pp. 2795-2801
    • Clarke, S.H.1    Staudt, L.M.2    Kavaler, J.3    Schwartz, D.4    Gerhard, W.U.5    Weigert, M.G.6
  • 8
    • 0008476550 scopus 로고
    • Generation of antibody diversity in the immune response of BALB/c mice to influenza virus hemagglutinin
    • McKean D, Huppe R, Bell M, Staudt L, Gerhard L, Weigert M. Generation of antibody diversity in the immune response of BALB/c mice to influenza virus hemagglutinin. Proc Natl Acad Sci USA 1984;81:3180-3192.
    • (1984) Proc Natl Acad Sci USA , vol.81 , pp. 3180-3192
    • McKean, D.1    Huppe, R.2    Bell, M.3    Staudt, L.4    Gerhard, L.5    Weigert, M.6
  • 9
    • 0024495483 scopus 로고
    • Primary in situ immune response in popliteal lymph nodes and spleen of mice after subcutaneous immunization with thymus-dependent or thymus-independent (Type 1 and 2) antigens
    • Delemarre FGA, Claussen E, Rooijen NV. Primary in situ immune response in popliteal lymph nodes and spleen of mice after subcutaneous immunization with thymus-dependent or thymus-independent (Type 1 and 2) antigens. Anat Rec 1989;223:152-157.
    • (1989) Anat Rec , vol.223 , pp. 152-157
    • Delemarre, F.G.A.1    Claussen, E.2    Rooijen, N.V.3
  • 10
    • 0025726702 scopus 로고
    • In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl) acetyl. I. The architecture and dynamics of responding cell populations
    • Jacob J, Kelsoe G. In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl) acetyl. I. The architecture and dynamics of responding cell populations. J Exp Med 1991;173:1165-1175.
    • (1991) J Exp Med , vol.173 , pp. 1165-1175
    • Jacob, J.1    Kelsoe, G.2
  • 11
    • 0027305024 scopus 로고
    • In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl) acetyl. III. The kinetics of V-region mutation and selection in germinal centers B cells
    • Jacob J, Przylepa J, Miller C, Kelsoe G. In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl) acetyl. III. The kinetics of V-region mutation and selection in germinal centers B cells. J Exp Med 1993;178:1293-1307.
    • (1993) J Exp Med , vol.178 , pp. 1293-1307
    • Jacob, J.1    Przylepa, J.2    Miller, C.3    Kelsoe, G.4
  • 12
    • 0020562931 scopus 로고
    • Relationship of germinal centers in lymphoid tissue to immunologic memory. IV Transfer of B cell memory with lymph node cells fractionated according to their receptor for peanut agglutinin
    • Coico RF, Bhogal BS, Thorbecke GJ. Relationship of germinal centers in lymphoid tissue to immunologic memory. IV Transfer of B cell memory with lymph node cells fractionated according to their receptor for peanut agglutinin. J Immunol 1983;131:2254-2257.
    • (1983) J Immunol , vol.131 , pp. 2254-2257
    • Coico, R.F.1    Bhogal, B.S.2    Thorbecke, G.J.3
  • 18
    • 0026334486 scopus 로고
    • Aging and immune function
    • Miller RA. Aging and immune function. Int Rev Cytology 1991;124:187-215.
    • (1991) Int Rev Cytology , vol.124 , pp. 187-215
    • Miller, R.A.1
  • 20
    • 0025269282 scopus 로고
    • Decreased specific antibody synthesis in old adults: Decreased potency of antigen-specific B cells with aging
    • Burns EA, Lum LG, Scigneuret MC, Giddings BR, Goodwin JS. Decreased specific antibody synthesis in old adults: decreased potency of antigen-specific B cells with aging. Mech Ageing Dev 1990;53:229-241.
    • (1990) Mech Ageing Dev , vol.53 , pp. 229-241
    • Burns, E.A.1    Lum, L.G.2    Scigneuret, M.C.3    Giddings, B.R.4    Goodwin, J.S.5
  • 21
    • 0018085612 scopus 로고
    • Failure to response to influenza vaccine in the aged: Correlation with B-cell number and function
    • Phair J, Kauffman A, Bjornson A, Adams L, Linneman C Jr. Failure to response to influenza vaccine in the aged: correlation with B-cell number and function. J Lab Clin Med 1978;92:822-828.
    • (1978) J Lab Clin Med , vol.92 , pp. 822-828
    • Phair, J.1    Kauffman, A.2    Bjornson, A.3    Adams, L.4    Linneman Jr., C.5
  • 22
    • 0023205439 scopus 로고
    • Alterations in the human response to the hepatitis B vaccine among the elderly
    • Cook JM, et al. Alterations in the human response to the hepatitis B vaccine among the elderly. Cell Immunol 1987;109:89-96.
    • (1987) Cell Immunol , vol.109 , pp. 89-96
    • Cook, J.M.1
  • 23
    • 0017229474 scopus 로고
    • In vitro immune response to the 2,4,6-trinitrophenyl determinant in aged C57BL/6 mice: Changes in the humoral response to avidity for the TNP determinant and responsiveness to LPS effect with aging
    • Kishimoto S, Takahama T, Mizumachi H. In vitro immune response to the 2,4,6-trinitrophenyl determinant in aged C57BL/6 mice: changes in the humoral response to avidity for the TNP determinant and responsiveness to LPS effect with aging. J Immunol 1976;116:294-300.
    • (1976) J Immunol , vol.116 , pp. 294-300
    • Kishimoto, S.1    Takahama, T.2    Mizumachi, H.3
  • 24
    • 0017167094 scopus 로고
    • Immunological studies of aging. II. Loss of IgG and high avidity plaque forming cells and increased suppressor cell activity in aging mice
    • Goidl EA, Innes JB, Weksler ME. Immunological studies of aging. II. Loss of IgG and high avidity plaque forming cells and increased suppressor cell activity in aging mice. J Exp Med 1976;144:1037-1048.
    • (1976) J Exp Med , vol.144 , pp. 1037-1048
    • Goidl, E.A.1    Innes, J.B.2    Weksler, M.E.3
  • 25
    • 0017656871 scopus 로고
    • The affinity and spectrum of crossreactivity of antibody production in senescent mice: The IgM response
    • Zharhary D, Segev Y, Gershon H. The affinity and spectrum of crossreactivity of antibody production in senescent mice: the IgM response. Mech Ageing Dev 1977;6:385-392.
    • (1977) Mech Ageing Dev , vol.6 , pp. 385-392
    • Zharhary, D.1    Segev, Y.2    Gershon, H.3
  • 26
    • 0018085443 scopus 로고
    • Age dependent variations of antibody avidity
    • Doria G, D'Agostaro G, Poretti A. Age dependent variations of antibody avidity. Immunology 1978;35:601-611.
    • (1978) Immunology , vol.35 , pp. 601-611
    • Doria, G.1    D'Agostaro, G.2    Poretti, A.3
  • 27
    • 0018166880 scopus 로고
    • Immunological studies of aging. IV. The contribution of thymic involution to the immune deficiencies of aging mice
    • Weksler ME, Innes JB, Goldstein G. Immunological studies of aging. IV. The contribution of thymic involution to the immune deficiencies of aging mice. J Exp Med 1978;148:996-1006.
    • (1978) J Exp Med , vol.148 , pp. 996-1006
    • Weksler, M.E.1    Innes, J.B.2    Goldstein, G.3
  • 30
    • 0027252520 scopus 로고
    • Repertoire diversity of antibody response to bacterial antigens in aged mice. III. Phosphorylcholine antibody from young and aged mice differ in structure and protective activity against infection with Streptococcus pneumoniae
    • Nicoletti C, Yang X, Cerny J. Repertoire diversity of antibody response to bacterial antigens in aged mice. III. Phosphorylcholine antibody from young and aged mice differ in structure and protective activity against infection with Streptococcus pneumoniae. J Immunol 1993 150:543-549.
    • (1993) J Immunol , vol.150 , pp. 543-549
    • Nicoletti, C.1    Yang, X.2    Cerny, J.3
  • 32
    • 0022169940 scopus 로고
    • Autoimmunity and aging
    • Cruse M, Lewis RE, eds. Basel: Karger
    • Hirokawa K. Autoimmunity and aging. In: Cruse M, Lewis RE, eds. Concepts of Immunopathology. Vol I Basel: Karger; 1985. p. 251-288.
    • (1985) Concepts of Immunopathology , vol.1 , pp. 251-288
    • Hirokawa, K.1
  • 33
    • 0022444347 scopus 로고
    • T cell involvement in the decrease of antigen-responsive B cells in aged mice
    • Zharhary D. T cell involvement in the decrease of antigen-responsive B cells in aged mice. Eur J Immunol 1986;16:1175-1178.
    • (1986) Eur J Immunol , vol.16 , pp. 1175-1178
    • Zharhary, D.1
  • 34
    • 0023850713 scopus 로고
    • Old mice recover the ability to produce IgG and high-avidity antibody following irradiation with partial bone marrow shilding
    • Tsuda T, Kim YT, Siskind GW, Weksler ME. Old mice recover the ability to produce IgG and high-avidity antibody following irradiation with partial bone marrow shilding. Proc Natl Acad Sci USA 1988;85:1169-1173.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 1169-1173
    • Tsuda, T.1    Kim, Y.T.2    Siskind, G.W.3    Weksler, M.E.4
  • 37
    • 0025726702 scopus 로고
    • In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl) acetyl. 1. The architecture and dynamics of responding cell populations
    • Jacob J, Kassir R, Kelsoe G. In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl) acetyl. 1. The architecture and dynamics of responding cell populations. J Exp Med 1991;173;1165-1175.
    • (1991) J Exp Med , vol.173 , pp. 1165-1175
    • Jacob, J.1    Kassir, R.2    Kelsoe, G.3
  • 38
    • 0025601012 scopus 로고
    • The repertoire of somatic antibody mutants accumulating in the memory compartment after primary immunization is restricted through affinity maturation and mirrors that expressed in the secondary response
    • Weiss U, Rajewsky K. The repertoire of somatic antibody mutants accumulating in the memory compartment after primary immunization is restricted through affinity maturation and mirrors that expressed in the secondary response. J Exp Med 1990;172:1681-1689.
    • (1990) J Exp Med , vol.172 , pp. 1681-1689
    • Weiss, U.1    Rajewsky, K.2
  • 39
    • 0029918498 scopus 로고    scopus 로고
    • Relative contribution of T and B cells to hypermutation and selection of the antibody repertoire in germinal centers of aged mice
    • Yang X, Stedra J, Cerny J. Relative contribution of T and B cells to hypermutation and selection of the antibody repertoire in germinal centers of aged mice. J Exp Med 1996;183:959-970.
    • (1996) J Exp Med , vol.183 , pp. 959-970
    • Yang, X.1    Stedra, J.2    Cerny, J.3
  • 40
    • 0025783070 scopus 로고
    • Molecular characterization of single memory B cells
    • McHeyzer-William GC, Nossal GJ, Lalor PA. Molecular characterization of single memory B cells. Nature 1991;350:502-505.
    • (1991) Nature , vol.350 , pp. 502-505
    • McHeyzer-William, G.C.1    Nossal, G.J.2    Lalor, P.A.3
  • 41
    • 0026519867 scopus 로고
    • Cell selection strategies for making antibodies from variable gene libraries: Trapping the memory pool
    • Hawkins RE, Winter G. Cell selection strategies for making antibodies from variable gene libraries: trapping the memory pool. Eur J Immunol 1992;22:867-870.
    • (1992) Eur J Immunol , vol.22 , pp. 867-870
    • Hawkins, R.E.1    Winter, G.2
  • 42
    • 0030938144 scopus 로고    scopus 로고
    • Germinal center development
    • Liu Y-J, Arpin C. Germinal center development. Immunol Rev 1997;156:111-126.
    • (1997) Immunol Rev , vol.156 , pp. 111-126
    • Liu, Y.-J.1    Arpin, C.2
  • 43
    • 0015319571 scopus 로고
    • Splenic foci of antibody-producing cells to two distinct somatic antigens present on one bacterium
    • Cerny J, McAlack RF, Friedman H. Splenic foci of antibody-producing cells to two distinct somatic antigens present on one bacterium. Immunology 1972;22:573-587.
    • (1972) Immunology , vol.22 , pp. 573-587
    • Cerny, J.1    McAlack, R.F.2    Friedman, H.3
  • 44
    • 0026670190 scopus 로고
    • In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl) acetyl. II. A common clonal origin for periateriolar lymphoid sheath-associated foci and germinal centers
    • Jacob J, Kelsoe G. In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl) acetyl. II. A common clonal origin for periateriolar lymphoid sheath-associated foci and germinal centers. J Exp Med 1992;176:679-687.
    • (1992) J Exp Med , vol.176 , pp. 679-687
    • Jacob, J.1    Kelsoe, G.2
  • 45
    • 0018881864 scopus 로고
    • Age influence on the immune system
    • Makinodan T, Kay MM. Age influence on the immune system. Adv Immunol 1980;29:287-330.
    • (1980) Adv Immunol , vol.29 , pp. 287-330
    • Makinodan, T.1    Kay, M.M.2
  • 46
    • 0031457217 scopus 로고    scopus 로고
    • Immunization with immune complex alters the repertoire of antigen-reactive B cells in the germinal centers
    • In press
    • Nie X, Basu S, Cerny J. Immunization with immune complex alters the repertoire of antigen-reactive B cells in the germinal centers. Eur J Immunol 1997 (In press).
    • (1997) Eur J Immunol
    • Nie, X.1    Basu, S.2    Cerny, J.3
  • 47
    • 0028983212 scopus 로고
    • H hypermutation is absent in the germinal centers of aged mice
    • H hypermutation is absent in the germinal centers of aged mice. J Immunol 1995;155:3377-3384.
    • (1995) J Immunol , vol.155 , pp. 3377-3384
    • Miller, C.1    Kelsoe, G.2
  • 49
    • 0021118013 scopus 로고
    • Aging and the mucosal associated lymphoid system
    • Wade AW, Szewczuk MR. Aging and the mucosal associated lymphoid system. Adv Immunol 1984;36:143-185
    • (1984) Adv Immunol , vol.36 , pp. 143-185
    • Wade, A.W.1    Szewczuk, M.R.2
  • 50
    • 0030035583 scopus 로고    scopus 로고
    • The aging immune system: Primer and prospectus
    • Miller RA. The aging immune system: primer and prospectus. Science 1996;273:70-74.
    • (1996) Science , vol.273 , pp. 70-74
    • Miller, R.A.1
  • 51
    • 0028661071 scopus 로고
    • Lack of B7-2 expression in the germinal centers of aged mice
    • Miller C, Kelsoe G, Han S. Lack of B7-2 expression in the germinal centers of aged mice. Aging Immunol Infect Dis 1994;5:249-257.
    • (1994) Aging Immunol Infect Dis , vol.5 , pp. 249-257
    • Miller, C.1    Kelsoe, G.2    Han, S.3
  • 52
    • 0025315195 scopus 로고
    • Kinetics of germinal center development in lymph nodes of young and aging immune mice
    • Szakal AK, Taylor JK, Smith JP, Kosco MH, Burton GF, Tew JG. Kinetics of germinal center development in lymph nodes of young and aging immune mice. Anat Rec 1990;222:475-485.
    • (1990) Anat Rec , vol.222 , pp. 475-485
    • Szakal, A.K.1    Taylor, J.K.2    Smith, J.P.3    Kosco, M.H.4    Burton, G.F.5    Tew, J.G.6
  • 53
    • 0028041170 scopus 로고
    • Monoclonal antibodies to murine CD40 define two distinct functional epitopes
    • Heath AW, Wu WW, Howard MC. Monoclonal antibodies to murine CD40 define two distinct functional epitopes. Eur J Immunol 1994;24:1828-1834.
    • (1994) Eur J Immunol , vol.24 , pp. 1828-1834
    • Heath, A.W.1    Wu, W.W.2    Howard, M.C.3
  • 54
    • 0031571318 scopus 로고    scopus 로고
    • Induction of germinal center B cell markers in vitro by activated CD4 T lymphocytes. The role of CD40 ligand, soluble factors and B cell antigen receptor cross-linking
    • Lahvis GP, Cerny J. Induction of germinal center B cell markers in vitro by activated CD4 T lymphocytes. The role of CD40 ligand, soluble factors and B cell antigen receptor cross-linking. J Immunol 1997;159:1783-1793.
    • (1997) J Immunol , vol.159 , pp. 1783-1793
    • Lahvis, G.P.1    Cerny, J.2
  • 55
    • 0021836202 scopus 로고
    • Distinct functional phenotypes of cloned Ia-restricted helper T cells
    • Kim J, Woods A, Becker-Dunn E, Bottomly K. Distinct functional phenotypes of cloned Ia-restricted helper T cells. J Exp Med 1985;162:188-201.
    • (1985) J Exp Med , vol.162 , pp. 188-201
    • Kim, J.1    Woods, A.2    Becker-Dunn, E.3    Bottomly, K.4
  • 56
    • 0023009192 scopus 로고
    • A clonal T cell line that selectively augments antibody responses of phosphorylcholine-specific B cells bearing the T15 idiotype
    • Becker-Dunn E, Kim J, Bottomly K. A clonal T cell line that selectively augments antibody responses of phosphorylcholine-specific B cells bearing the T15 idiotype. J Mol Cell Immunol 1986;2:209-217.
    • (1986) J Mol Cell Immunol , vol.2 , pp. 209-217
    • Becker-Dunn, E.1    Kim, J.2    Bottomly, K.3
  • 57
    • 0024338127 scopus 로고
    • Restricted idiotype profile of anti-phosphorylcholine antibodies induced by carrier-specific helper T cell clones
    • Strickland FM, Cerny J, Burrier P, Infante AJ. Restricted idiotype profile of anti-phosphorylcholine antibodies induced by carrier-specific helper T cell clones. Eur J Immunol 1989;19:971-976.
    • (1989) Eur J Immunol , vol.19 , pp. 971-976
    • Strickland, F.M.1    Cerny, J.2    Burrier, P.3    Infante, A.J.4
  • 58
    • 0022297171 scopus 로고
    • The T-cell-independent immune response to the hapten NP uses a large repertoire of heavy chain genes
    • Maizels N, Bothwell A. The T-cell-independent immune response to the hapten NP uses a large repertoire of heavy chain genes. Cell 1985;43:715-720.
    • (1985) Cell , vol.43 , pp. 715-720
    • Maizels, N.1    Bothwell, A.2
  • 59
    • 0027159596 scopus 로고
    • + T cells from young and old mice
    • + T cells from young and old mice. J Immunol 1993;150:3602-3614.
    • (1993) J Immunol , vol.150 , pp. 3602-3614
    • Hobbs, M.V.1
  • 61
    • 0028330986 scopus 로고
    • Distinct pathways of B cell differentiation. I. Residual T cells in athymic mice support the development of splenic germinal centers and B cell memory without in induction of antibody
    • Stedra J, Cerny J. Distinct pathways of B cell differentiation. I. Residual T cells in athymic mice support the development of splenic germinal centers and B cell memory without in induction of antibody. J Immunol 1994;152:1718-1726.
    • (1994) J Immunol , vol.152 , pp. 1718-1726
    • Stedra, J.1    Cerny, J.2


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