메뉴 건너뛰기




Volumn 201, Issue 8, 2018, Pages 2354-2368

Influenza a virus infection causes chronic lung disease linked to sites of active viral RNA remnants

Author keywords

[No Author keywords available]

Indexed keywords

IL17A PROTEIN, MOUSE; INTERLEUKIN 13; INTERLEUKIN 17; MUC5AC PROTEIN, MOUSE; MUCIN 5AC; STAT6 PROTEIN; VIRUS RNA;

EID: 85054772691     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1800671     Document Type: Article
Times cited : (67)

References (96)
  • 1
    • 84864742968 scopus 로고    scopus 로고
    • Asthma as a chronic disease of the innate and adaptive immune systems responding to viruses and allergens
    • Holtzman, M. J. 2012. Asthma as a chronic disease of the innate and adaptive immune systems responding to viruses and allergens. J. Clin. Invest. 122: 2741-2748.
    • (2012) J. Clin. Invest. , vol.122 , pp. 2741-2748
    • Holtzman, M.J.1
  • 8
    • 84937023870 scopus 로고    scopus 로고
    • Association between respiratory infections in early life and later asthma is independent of virus type
    • Bønnelykke, K., N. H. Vissing, A. Sevelsted, S. L. Johnston, and H. Bisgaard. 2015. Association between respiratory infections in early life and later asthma is independent of virus type. J. Allergy Clin. Immunol. 136: 81-86.e4.
    • (2015) J. Allergy Clin. Immunol. , vol.136 , pp. 81-86e4
    • Bønnelykke, K.1    Vissing, N.H.2    Sevelsted, A.3    Johnston, S.L.4    Bisgaard, H.5
  • 9
    • 0036070857 scopus 로고    scopus 로고
    • Viral induction of a chronic asthma phenotype and genetic segregation from the acute response
    • Walter, M. J., J. D. Morton, N. Kajiwara, E. Agapov, and M. J. Holtzman. 2002. Viral induction of a chronic asthma phenotype and genetic segregation from the acute response. J. Clin. Invest. 110: 165-175.
    • (2002) J. Clin. Invest. , vol.110 , pp. 165-175
    • Walter, M.J.1    Morton, J.D.2    Kajiwara, N.3    Agapov, E.4    Holtzman, M.J.5
  • 20
    • 84863707107 scopus 로고    scopus 로고
    • Stimulation of immature lung macrophages with intranasal interferon gamma in a novel neonatal mouse model of respiratory syncytial virus infection
    • Empey, K. M., J. G. Orend, R. S. Peebles, Jr., L. Egaña, K. A. Norris, T. D. Oury, and J. K. Kolls. 2012. Stimulation of immature lung macrophages with intranasal interferon gamma in a novel neonatal mouse model of respiratory syncytial virus infection. PLoS One 7: e40499.
    • (2012) PLoS One , vol.7 , pp. e40499
    • Empey, K.M.1    Orend, J.G.2    Peebles, R.S.3    Egaña, L.4    Norris, K.A.5    Oury, T.D.6    Kolls, J.K.7
  • 26
    • 84947866665 scopus 로고    scopus 로고
    • PARP9-DTX3L ubiquitin ligase targets host histone H2BJ and viral 3C protease to enhance interferon signaling and control viral infection
    • Zhang, Y., D. Mao, W. T. Roswit, X. Jin, A. C. Patel, D. A. Patel, E. Agapov, Z. Wang, R. M. Tidwell, J. J. Atkinson, et al. 2015. PARP9-DTX3L ubiquitin ligase targets host histone H2BJ and viral 3C protease to enhance interferon signaling and control viral infection. Nat. Immunol. 16: 1215-1227.
    • (2015) Nat. Immunol. , vol.16 , pp. 1215-1227
    • Zhang, Y.1    Mao, D.2    Roswit, W.T.3    Jin, X.4    Patel, A.C.5    Patel, D.A.6    Agapov, E.7    Wang, Z.8    Tidwell, R.M.9    Atkinson, J.J.10
  • 27
    • 84902198586 scopus 로고    scopus 로고
    • IFN-α suppresses GATA3 transcription from a distal exon and promotes H3K27 trimethylation of the CNS-1 enhancer in human Th2 cells
    • Huber, J. P., S. R. Gonzales-van Horn, K. T. Roybal, M. A. Gill, and J. D. Farrar. 2014. IFN-α suppresses GATA3 transcription from a distal exon and promotes H3K27 trimethylation of the CNS-1 enhancer in human Th2 cells. J. Immunol. 192: 5687-5694.
    • (2014) J. Immunol. , vol.192 , pp. 5687-5694
    • Huber, J.P.1    Gonzales-Van Horn, S.R.2    Roybal, K.T.3    Gill, M.A.4    Farrar, J.D.5
  • 28
    • 0033850483 scopus 로고    scopus 로고
    • Wheezing following lower respiratory tract infections with respiratory syncytial virus and influenza A in infancy
    • Eriksson, M., R. Bennet, and A. Nilsson. 2000. Wheezing following lower respiratory tract infections with respiratory syncytial virus and influenza A in infancy. Pediatr. Allergy Immunol. 11: 193-197.
    • (2000) Pediatr. Allergy Immunol. , vol.11 , pp. 193-197
    • Eriksson, M.1    Bennet, R.2    Nilsson, A.3
  • 29
    • 0032827121 scopus 로고    scopus 로고
    • Respiratory syncytial and other virus infections in persons with chronic cardiopulmonary disease
    • Walsh, E. E., A. R. Falsey, and P. A. Hennessey. 1999. Respiratory syncytial and other virus infections in persons with chronic cardiopulmonary disease. Am. J. Respir. Crit. Care Med. 160: 791-795.
    • (1999) Am. J. Respir. Crit. Care Med. , vol.160 , pp. 791-795
    • Walsh, E.E.1    Falsey, A.R.2    Hennessey, P.A.3
  • 31
  • 32
    • 80155148257 scopus 로고    scopus 로고
    • Distal airway stem cells yield alveoli in vitro and during lung regeneration following H1N1 influenza infection
    • Kumar, P. A., Y. Hu, Y. Yamamoto, N. B. Hoe, T. S. Wei, D. Mu, Y. Sun, L. S. Joo, R. Dagher, E. M. Zielonka, et al. 2011. Distal airway stem cells yield alveoli in vitro and during lung regeneration following H1N1 influenza infection. Cell 147: 525-538.
    • (2011) Cell , vol.147 , pp. 525-538
    • Kumar, P.A.1    Hu, Y.2    Yamamoto, Y.3    Hoe, N.B.4    Wei, T.S.5    Mu, D.6    Sun, Y.7    Joo, L.S.8    Dagher, R.9    Zielonka, E.M.10
  • 35
    • 34250879032 scopus 로고    scopus 로고
    • Time-dependent airway epithelial and inflammatory cell responses induced by influenza virus A/PR/8/34 in C57BL/6 mice
    • Buchweitz, J. P., J. R. Harkema, and N. E. Kaminski. 2007. Time-dependent airway epithelial and inflammatory cell responses induced by influenza virus A/PR/8/34 in C57BL/6 mice. Toxicol. Pathol. 35: 424-435.
    • (2007) Toxicol. Pathol. , vol.35 , pp. 424-435
    • Buchweitz, J.P.1    Harkema, J.R.2    Kaminski, N.E.3
  • 36
    • 0242668753 scopus 로고    scopus 로고
    • Influenza A virus infection inhibits the efficient recruitment of Th2 cells into the airways and the development of airway eosinophilia
    • Wohlleben, G., J. Müller, U. Tatsch, C. Hambrecht, U. Herz, H. Renz, E. Schmitt, H. Moll, and K. J. Erb. 2003. Influenza A virus infection inhibits the efficient recruitment of Th2 cells into the airways and the development of airway eosinophilia. J. Immunol. 170: 4601-4611.
    • (2003) J. Immunol. , vol.170 , pp. 4601-4611
    • Wohlleben, G.1    Müller, J.2    Tatsch, U.3    Hambrecht, C.4    Herz, U.5    Renz, H.6    Schmitt, E.7    Moll, H.8    Erb, K.J.9
  • 37
    • 0029876629 scopus 로고    scopus 로고
    • Stat6 is required for mediating responses to IL-4 and for development of Th2 cells
    • Kaplan, M. H., U. Schindler, S. T. Smiley, and M. J. Grusby. 1996. Stat6 is required for mediating responses to IL-4 and for development of Th2 cells. Immunity 4: 313-319.
    • (1996) Immunity , vol.4 , pp. 313-319
    • Kaplan, M.H.1    Schindler, U.2    Smiley, S.T.3    Grusby, M.J.4
  • 38
    • 0036754255 scopus 로고    scopus 로고
    • Antigen-specific T cell sensitization is impaired in IL-17-deficient mice, causing suppression of allergic cellular and humoral responses
    • Nakae, S., Y. Komiyama, A. Nambu, K. Sudo, M. Iwase, I. Homma, K. Sekikawa, M. Asano, and Y. Iwakura. 2002. Antigen-specific T cell sensitization is impaired in IL-17-deficient mice, causing suppression of allergic cellular and humoral responses. Immunity 17: 375-387.
    • (2002) Immunity , vol.17 , pp. 375-387
    • Nakae, S.1    Komiyama, Y.2    Nambu, A.3    Sudo, K.4    Iwase, M.5    Homma, I.6    Sekikawa, K.7    Asano, M.8    Iwakura, Y.9
  • 40
    • 84880666503 scopus 로고    scopus 로고
    • Influenza: Propagation, quantification, and storage
    • Chapter 15: Unit 15G.1
    • Szretter, K. J., A. L. Balish, and J. M. Katz. 2006. Influenza: propagation, quantification, and storage. Curr. Protoc. Microbiol. Chapter 15: Unit 15G.1.
    • (2006) Curr. Protoc. Microbiol.
    • Szretter, K.J.1    Balish, A.L.2    Katz, J.M.3
  • 41
    • 84856170852 scopus 로고    scopus 로고
    • Age-specific absolute and relative organ weight distributions for B6C3F1 mice
    • Marino, D. J. 2012. Age-specific absolute and relative organ weight distributions for B6C3F1 mice. J. Toxicol. Environ. Health A 75: 76-99.
    • (2012) J. Toxicol. Environ. Health A , vol.75 , pp. 76-99
    • Marino, D.J.1
  • 42
    • 0027935048 scopus 로고
    • Demonstration of in vitro infection of chimpanzee hepatocytes with hepatitis C virus using strand-specific RT/PCR
    • Lanford, R. E., C. Sureau, J. R. Jacob, R. White, and T. R. Fuerst. 1994. Demonstration of in vitro infection of chimpanzee hepatocytes with hepatitis C virus using strand-specific RT/PCR. Virology 202: 606-614.
    • (1994) Virology , vol.202 , pp. 606-614
    • Lanford, R.E.1    Sureau, C.2    Jacob, J.R.3    White, R.4    Fuerst, T.R.5
  • 46
    • 24344435571 scopus 로고    scopus 로고
    • Unexpected prolonged presentation of influenza antigens promotes CD4 T cell memory generation
    • Jelley-Gibbs, D. M., D. M. Brown, J. P. Dibble, L. Haynes, S. M. Eaton, and S. L. Swain. 2005. Unexpected prolonged presentation of influenza antigens promotes CD4 T cell memory generation. J. Exp. Med. 202: 697-706.
    • (2005) J. Exp. Med. , vol.202 , pp. 697-706
    • Jelley-Gibbs, D.M.1    Brown, D.M.2    Dibble, J.P.3    Haynes, L.4    Eaton, S.M.5    Swain, S.L.6
  • 47
    • 33645971304 scopus 로고    scopus 로고
    • Residual antigen presentation after influenza virus infection affects CD8 T cell activation and migration
    • Zammit, D. J., D. L. Turner, K. D. Klonowski, L. Lefrançois, and L. S. Cauley. 2006. Residual antigen presentation after influenza virus infection affects CD8 T cell activation and migration. Immunity 24: 439-449.
    • (2006) Immunity , vol.24 , pp. 439-449
    • Zammit, D.J.1    Turner, D.L.2    Klonowski, K.D.3    Lefrançois, L.4    Cauley, L.S.5
  • 49
    • 77953499055 scopus 로고    scopus 로고
    • Antigen persistence and the control of local T cell memory by migrant respiratory dendritic cells after acute virus infection
    • Kim, T. S., M. M. Hufford, J. Sun, Y. X. Fu, and T. J. Braciale. 2010. Antigen persistence and the control of local T cell memory by migrant respiratory dendritic cells after acute virus infection. J. Exp. Med. 207: 1161-1172.
    • (2010) J. Exp. Med. , vol.207 , pp. 1161-1172
    • Kim, T.S.1    Hufford, M.M.2    Sun, J.3    Fu, Y.X.4    Braciale, T.J.5
  • 59
    • 84862087268 scopus 로고    scopus 로고
    • Monitoring in vivo changes in lung microstructure with 3He MRI in Sendai virus-infected mice
    • Wang, W., N. M. Nguyen, E. Agapov, M. J. Holtzman, and J. C. Woods. 2012. Monitoring in vivo changes in lung microstructure with 3He MRI in Sendai virus-infected mice. J. Appl. Physiol. 112: 1593-1599.
    • (2012) J. Appl. Physiol. , vol.112 , pp. 1593-1599
    • Wang, W.1    Nguyen, N.M.2    Agapov, E.3    Holtzman, M.J.4    Woods, J.C.5
  • 61
    • 0035139418 scopus 로고    scopus 로고
    • Production of interferon-gamma by influenza hemagglutinin-specific CD8 effector T cells influences the development of pulmonary immunopathology
    • Wiley, J. A., A. Cerwenka, J. R. Harkema, R. W. Dutton, and A. G. Harmsen. 2001. Production of interferon-gamma by influenza hemagglutinin-specific CD8 effector T cells influences the development of pulmonary immunopathology. Am. J. Pathol. 158: 119-130.
    • (2001) Am. J. Pathol. , vol.158 , pp. 119-130
    • Wiley, J.A.1    Cerwenka, A.2    Harkema, J.R.3    Dutton, R.W.4    Harmsen, A.G.5
  • 65
    • 77955286120 scopus 로고    scopus 로고
    • Risk factors for hospitalisation and poor outcome with pandemic A/H1N1 influenza: United Kingdom first wave (May-September 2009)
    • Influenza Clinical Information Network (FLU-CIN).
    • Nguyen-Van-Tam, J. S., P. J. Openshaw, A. Hashim, E. M. Gadd, W. S. Lim, M. G. Semple, R. C. Read, B. L. Taylor, S. J. Brett, J. McMenamin, et al; Influenza Clinical Information Network (FLU-CIN). 2010. Risk factors for hospitalisation and poor outcome with pandemic A/H1N1 influenza: United Kingdom first wave (May-September 2009). Thorax 65: 645-651.
    • (2010) Thorax , vol.65 , pp. 645-651
    • Nguyen-Van-Tam, J.S.1    Openshaw, P.J.2    Hashim, A.3    Gadd, E.M.4    Lim, W.S.5    Semple, M.G.6    Read, R.C.7    Taylor, B.L.8    Brett, S.J.9    McMenamin, J.10
  • 69
    • 77956955243 scopus 로고    scopus 로고
    • Complement-mediated regulation of the IL-17A axis is a central genetic determinant of the severity of experimental allergic asthma
    • Lajoie, S., I. P. Lewkowich, Y. Suzuki, J. R. Clark, A. A. Sproles, K. Dienger, A. L. Budelsky, and M. Wills-Karp. 2010. Complement-mediated regulation of the IL-17A axis is a central genetic determinant of the severity of experimental allergic asthma. Nat. Immunol. 11: 928-935.
    • (2010) Nat. Immunol. , vol.11 , pp. 928-935
    • Lajoie, S.1    Lewkowich, I.P.2    Suzuki, Y.3    Clark, J.R.4    Sproles, A.A.5    Dienger, K.6    Budelsky, A.L.7    Wills-Karp, M.8
  • 73
    • 84930470540 scopus 로고    scopus 로고
    • IL-17A is elevated in end-stage chronic obstructive pulmonary disease and contributes to cigarette smoke-induced lymphoid neogenesis
    • Roos, A. B., C. Sandén, M. Mori, L. Bjermer, M. R. Stampfli, and J. S. Erjefält. 2015. IL-17A is elevated in end-stage chronic obstructive pulmonary disease and contributes to cigarette smoke-induced lymphoid neogenesis. Am. J. Respir. Crit. Care Med. 191: 1232-1241.
    • (2015) Am. J. Respir. Crit. Care Med. , vol.191 , pp. 1232-1241
    • Roos, A.B.1    Sandén, C.2    Mori, M.3    Bjermer, L.4    Stampfli, M.R.5    Erjefält, J.S.6
  • 77
    • 70349871248 scopus 로고    scopus 로고
    • Allergic sensitization through the airway primes Th17- dependent neutrophilia and airway hyperresponsiveness
    • Wilson, R. H., G. S. Whitehead, H. Nakano, M. E. Free, J. K. Kolls, and D. N. Cook. 2009. Allergic sensitization through the airway primes Th17- dependent neutrophilia and airway hyperresponsiveness. Am. J. Respir. Crit. Care Med. 180: 720-730.
    • (2009) Am. J. Respir. Crit. Care Med. , vol.180 , pp. 720-730
    • Wilson, R.H.1    Whitehead, G.S.2    Nakano, H.3    Free, M.E.4    Kolls, J.K.5    Cook, D.N.6
  • 78
    • 84903398807 scopus 로고    scopus 로고
    • Targeting IL-1b and IL-17A driven inflammation during influenza-induced exacerbations of chronic lung inflammation
    • Sichelstiel, A., K. Yadava, A. Trompette, O. Salami, Y. Iwakura, L. P. Nicod, and B. J. Marsland. 2014. Targeting IL-1b and IL-17A driven inflammation during influenza-induced exacerbations of chronic lung inflammation. PLoS One 9: e98440.
    • (2014) PLoS One , vol.9 , pp. e98440
    • Sichelstiel, A.1    Yadava, K.2    Trompette, A.3    Salami, O.4    Iwakura, Y.5    Nicod, L.P.6    Marsland, B.J.7
  • 81
    • 84890026323 scopus 로고    scopus 로고
    • Randomized, double-blind, placebo-controlled study of brodalumab, a human anti-IL-17 receptor monoclonal antibody, in moderate to severe asthma
    • Busse, W. W., S. Holgate, E. Kerwin, Y. Chon, J. Feng, J. Lin, and S. L. Lin. 2013. Randomized, double-blind, placebo-controlled study of brodalumab, a human anti-IL-17 receptor monoclonal antibody, in moderate to severe asthma. Am. J. Respir. Crit. Care Med. 188: 1294-1302.
    • (2013) Am. J. Respir. Crit. Care Med. , vol.188 , pp. 1294-1302
    • Busse, W.W.1    Holgate, S.2    Kerwin, E.3    Chon, Y.4    Feng, J.5    Lin, J.6    Lin, S.L.7
  • 82
    • 85054774499 scopus 로고    scopus 로고
    • Study to assess the efficacy and safety of CJM112 in patients with inadequately controlled severe asthma
    • Novartis Pharmaceuticals. National Library of Medicine (US), Bethesda, MD. NLM Identifier: NCT03299686.. Accessed: August 29, 2018
    • Novartis Pharmaceuticals. 2018. Study to assess the efficacy and safety of CJM112 in patients with inadequately controlled severe asthma. In: ClinicalTrials. gov. National Library of Medicine (US), Bethesda, MD. NLM Identifier: NCT03299686. Available at http://clinicaltrials.gov/ct2/show/ NCT03299686. Accessed: August 29, 2018.
    • (2018) ClinicalTrials.gov
  • 84
    • 84994641774 scopus 로고    scopus 로고
    • Rare SOX2+ airway progenitor cells generate KRT5+ cells that repopulate damaged alveolar parenchyma following influenza virus infection
    • Ray, S., N. Chiba, C. Yao, X. Guan, A. M. McConnell, B. Brockway, L. Que, J. L. McQualter, and B. R. Stripp. 2016. Rare SOX2+ airway progenitor cells generate KRT5+ cells that repopulate damaged alveolar parenchyma following influenza virus infection. Stem Cell Reports 7: 817-825.
    • (2016) Stem Cell Reports , vol.7 , pp. 817-825
    • Ray, S.1    Chiba, N.2    Yao, C.3    Guan, X.4    McConnell, A.M.5    Brockway, B.6    Que, L.7    McQualter, J.L.8    Stripp, B.R.9
  • 89
    • 85047208099 scopus 로고    scopus 로고
    • Effect of tralokinumab, an interleukin-13 neutralising monoclonal antibody, on eosinophilic airway inflammation in uncontrolled moderate-to-severe asthma (MESOS): A multicentre, double-blind, randomised, placebo-controlled phase 2 trial
    • MESOS study investigators.
    • Russell, R. J., L. Chachi, J. M. FitzGerald, V. Backer, R. Olivenstein, I. L. Titlestad, C. S. Ulrik, T. Harrison, D. Singh, R. Chaudhuri, et al; MESOS study investigators. 2018. Effect of tralokinumab, an interleukin-13 neutralising monoclonal antibody, on eosinophilic airway inflammation in uncontrolled moderate-to-severe asthma (MESOS): a multicentre, double-blind, randomised, placebo-controlled phase 2 trial. Lancet Respir. Med. 6: 499-510.
    • (2018) Lancet Respir. Med. , vol.6 , pp. 499-510
    • Russell, R.J.1    Chachi, L.2    FitzGerald, J.M.3    Backer, V.4    Olivenstein, R.5    Titlestad, I.L.6    Ulrik, C.S.7    Harrison, T.8    Singh, D.9    Chaudhuri, R.10
  • 90
    • 85047094341 scopus 로고    scopus 로고
    • Tralokinumab for severe, uncontrolled asthma (STRATOS 1 and STRATOS 2): Two randomised, double-blind, placebocontrolled, phase 3 clinical trials
    • Panettieri, R. A., Jr., U. Sjöbring, A. Péterffy, P. Wessman, K. Bowen, E. Piper, G. Colice, and C. E. Brightling. 2018. Tralokinumab for severe, uncontrolled asthma (STRATOS 1 and STRATOS 2): two randomised, double-blind, placebocontrolled, phase 3 clinical trials. Lancet Respir. Med. 6: 511-525.
    • (2018) Lancet Respir. Med. , vol.6 , pp. 511-525
    • Panettieri, R.A.1    Sjöbring, U.2    Péterffy, A.3    Wessman, P.4    Bowen, K.5    Piper, E.6    Colice, G.7    Brightling, C.E.8
  • 91
    • 84860314088 scopus 로고    scopus 로고
    • Sputum eosinophilia can predict responsiveness to inhaled corticosteroid treatment in patients with overlap syndrome of COPD and asthma
    • Kitaguchi, Y., Y. Komatsu, K. Fujimoto, M. Hanaoka, and K. Kubo. 2012. Sputum eosinophilia can predict responsiveness to inhaled corticosteroid treatment in patients with overlap syndrome of COPD and asthma. Int. J. Chron. Obstruct. Pulmon. Dis. 7: 283-289.
    • (2012) Int. J. Chron. Obstruct. Pulmon. Dis. , vol.7 , pp. 283-289
    • Kitaguchi, Y.1    Komatsu, Y.2    Fujimoto, K.3    Hanaoka, M.4    Kubo, K.5
  • 96
    • 85054775054 scopus 로고    scopus 로고
    • Efficacy and safety study of GSK3772847 in subjects with moderately severe asthma
    • GlaxoSmithKline. National Library of Medicine (US), Bethesda, MD. NLM Identifier: NCT03207243. Accessed: August 29, 2018
    • GlaxoSmithKline. 2017. Efficacy and safety study of GSK3772847 in subjects with moderately severe asthma. In: ClinicalTrials.gov. National Library of Medicine (US), Bethesda, MD. NLM Identifier: NCT03207243. Available at: https://clinicaltrials.gov/ct2/show/NCT03207243. Accessed: August 29, 2018.
    • (2017) ClinicalTrials.gov


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.