Rare SOX2+ Airway Progenitor Cells Generate KRT5+ Cells that Repopulate Damaged Alveolar Parenchyma following Influenza Virus Infection

Stem Cell Reports

Volumn 7, Issue 5, 2016, Pages 817-825

  Ray, Samriddha ^a   Chiba, Norika ^a   Yao, Changfu ^a   Guan, Xiangrong ^a   McConnell, Alicia M ^a,b   Brockway, Brian ^b   Que, Loretta ^b   McQualter, Jonathan L ^a   Stripp, Barry R ^a,b  

^a CEDARS SINAI MEDICAL CENTER   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

influenza virus; keratin 5; lung injury; lung repair; progenitor cells; SCGB1A1 lineage; SOX2 lineage; wound repair

Indexed keywords

CYTOKERATIN 5; PROTEIN; PROTEIN SCGB1A1; TRANSCRIPTION FACTOR SOX2; UNCLASSIFIED DRUG; BIOLOGICAL MARKER; TRANSCRIPTION FACTOR SOX;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DAMAGE; CELL POPULATION; CELL PROLIFERATION; CONTROLLED STUDY; EPITHELIUM CELL; INFLUENZA; INFLUENZA VIRUS; LUNG ALVEOLUS; LUNG ALVEOLUS EPITHELIUM; LUNG INJURY; LUNG PARENCHYMA; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEM CELL; TISSUE REPAIR; WOUND HEALING; ANIMAL; BIOLOGICAL MODEL; CELL DIFFERENTIATION; CELL LINEAGE; CELL SELF-RENEWAL; CYTOLOGY; GENETICS; INFLUENZA A VIRUS (H1N1); LUNG ALVEOLUS EPITHELIUM CELL; METABOLISM; ORTHOMYXOVIRUS INFECTION; PATHOLOGY; RESPIRATORY MUCOSA; TRANSGENIC MOUSE; VIROLOGY;

ALVEOLAR EPITHELIAL CELLS; ANIMALS; BIOMARKERS; CELL DIFFERENTIATION; CELL LINEAGE; CELL SELF RENEWAL; INFLUENZA A VIRUS, H1N1 SUBTYPE; KERATIN-5; MICE; MICE, TRANSGENIC; MODELS, BIOLOGICAL; ORTHOMYXOVIRIDAE INFECTIONS; RESPIRATORY MUCOSA; SOXB1 TRANSCRIPTION FACTORS; STEM CELLS;

EID: 84994641774     PISSN: 22136711     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.stemcr.2016.09.010     Document Type: Article

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