Blocking airway mucous cell metaplasia by inhibiting EGFR antiapoptosis and IL-13 transdifferentiation signals

Journal of Clinical Investigation

Volumn 116, Issue 2, 2006, Pages 309-321

  Tyner, Jeffrey W ^a   Kim, Edy Y ^a   Ide, Kyotaro ^a   Pelletier, Mark R ^a   Roswit, William T ^a   Morton, Jeffrey D ^a   Battaile, John T ^a   Patel, Anand C ^a   Patterson, G Alexander ^a   Castro, Mario ^a   Spoor, Melanie S ^a   You, Yingjian ^a   Brody, Steven L ^a   Holtzman, Michael J ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE RECEPTOR ANTAGONIST; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR; INTERLEUKIN 13; INTERLEUKIN 13 RECEPTOR ALPHA 2 FC FRAGMENT COMPLEX; PELITINIB; UNCLASSIFIED DRUG;

ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CELL HYPERPLASIA; CILIATED EPITHELIUM; EPITHELIUM; GENETIC SUSCEPTIBILITY; GOBLET CELL; HUMAN; HUMAN TISSUE; INFLAMMATION; MOUSE; MUCOUS CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RESPIRATORY TRACT MUCOSA; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; APOPTOSIS; CELL DIFFERENTIATION; CELLS, CULTURED; EPITHELIAL CELLS; HUMANS; HYPERPLASIA; INTERLEUKIN-13; METAPLASIA; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MUCINS; RECEPTOR, EPIDERMAL GROWTH FACTOR; RESPIRATORY MUCOSA; SIGNAL TRANSDUCTION; VIRUSES;

EID: 32444436464     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI25167     Document Type: Article

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