IFN-g blocks development of an asthma phenotype in rhinovirus-infected baby mice by inhibiting type 2 innate lymphoid cells

American Journal of Respiratory Cell and Molecular Biology

Volumn 56, Issue 2, 2017, Pages 242-251

  Han, Mingyuan ^a   Hong, Jun Young ^a   Jaipalli, Suraj ^a   Rajput, Charu ^a   Lei, Jing ^a   Hinde, Joanna L ^a   Chen, Qiang ^a   Hershenson, Natalie M ^a   Bentley, J Kelley ^a   Hershenson, Marc B ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Asthma; IL 25; Neonatal; Rhinovirus; Type 2 innate lymphoid cells

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 1 RECEPTOR LIKE 1 PROTEIN; INTERLEUKIN 13; INTERLEUKIN 17 RECEPTOR; INTERLEUKIN 17 RECEPTOR B; INTERLEUKIN 25; INTERLEUKIN 5; MESSENGER RNA; MUCIN 5AC; THYMIC STROMAL LYMPHOPOIETIN; TRANSCRIPTION FACTOR GATA 3; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTHMA; BAGG ALBINO MOUSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RESPONSE; DRUG EFFECT; ENZYME LINKED IMMUNOSORBENT ASSAY; EX VIVO STUDY; FLOW CYTOMETRY; GENE EXPRESSION; HISTOPATHOLOGY; IMMATURITY; IMMUNOFLUORESCENCE MICROSCOPY; LYMPHOID CELL; METAPLASIA; MOUSE; NEWBORN; NONHUMAN; POLYMERASE CHAIN REACTION; PROTEIN EXPRESSION; QUANTITATIVE STUDY; RESPIRATORY TRACT ALLERGY; RHINOVIRUS INFECTION; TYPE 2 INNATE LYMPHOID CELL; ANIMAL; CELL LINEAGE; COMPLICATION; DRUG EFFECTS; EPITHELIUM CELL; GENE EXPRESSION REGULATION; GENETICS; HELA CELL LINE; HUMAN; IMMUNOLOGY; INNATE IMMUNITY; LYMPHOCYTE; METABOLISM; MUCUS; PHENOTYPE; PHYSIOLOGY; PICORNAVIRUS INFECTION; RHINOVIRUS; VIROLOGY;

ANIMALS; ANIMALS, NEWBORN; ASTHMA; CELL LINEAGE; EPITHELIAL CELLS; GENE EXPRESSION REGULATION; HELA CELLS; HUMANS; IMMUNITY, INNATE; INTERFERON-GAMMA; INTERLEUKIN-13; LYMPHOCYTES; METAPLASIA; MICE; MICE, INBRED BALB C; MUCUS; PHENOTYPE; PICORNAVIRIDAE INFECTIONS; RHINOVIRUS; RNA, MESSENGER;

EID: 85013031065     PISSN: 10441549     EISSN: 15354989     Source Type: Journal    
DOI: 10.1165/rcmb.2016-0056OC     Document Type: Article

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