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Volumn 119, Issue 9, 2018, Pages 7151-7165

Simultaneous downregulation of miR-21 and miR-155 through oleuropein for breast cancer prevention and therapy

Author keywords

anti cancer effect; breast cancer; miR 155; miR 21; miRNA; oleuropein

Indexed keywords

MICRORNA 155; MICRORNA 21; OLEUROPEIN; IRIDOID; MICRORNA; MIRN155 MICRORNA, HUMAN; MIRN21 MICRORNA, HUMAN;

EID: 85053615416     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.26754     Document Type: Article
Times cited : (43)

References (114)
  • 1
    • 84929310327 scopus 로고    scopus 로고
    • MicroRNA-based therapy and breast cancer: a comprehensive review of novel therapeutic strategies from diagnosis to treatment
    • Kaboli PJ, Rahmat A, Ismail P, Ling KH. MicroRNA-based therapy and breast cancer: a comprehensive review of novel therapeutic strategies from diagnosis to treatment. Pharmacol Res. 2015;97:104–121.
    • (2015) Pharmacol Res , vol.97 , pp. 104-121
    • Kaboli, P.J.1    Rahmat, A.2    Ismail, P.3    Ling, K.H.4
  • 2
    • 84946762173 scopus 로고    scopus 로고
    • Non Coding RNA Molecules as Potential Biomarkers in Breast Cancer
    • DE Leeneer K, Claes K. Non Coding RNA Molecules as Potential Biomarkers in Breast Cancer. Adv Exp Med Biol. 2015;867:263–275.
    • (2015) Adv Exp Med Biol , vol.867 , pp. 263-275
    • DE Leeneer, K.1    Claes, K.2
  • 3
    • 84930884627 scopus 로고    scopus 로고
    • Role of miR-155 in drug resistance of breast cancer
    • Yu DD, Lv MM, Chen WX, et al. Role of miR-155 in drug resistance of breast cancer. Tumour Biol. 2015;36:1395–1401.
    • (2015) Tumour Biol , vol.36 , pp. 1395-1401
    • Yu, D.D.1    Lv, M.M.2    Chen, W.X.3
  • 4
    • 84988354525 scopus 로고    scopus 로고
    • Regulation of epithelial-mesenchymal transition through microRNAs: clinical and biological significance of microRNAs in breast cancer
    • Peng F, Xiong L, Tang H, Peng C, Chen J. Regulation of epithelial-mesenchymal transition through microRNAs: clinical and biological significance of microRNAs in breast cancer. Tumor Biol. 2016;37:14463–14477.
    • (2016) Tumor Biol , vol.37 , pp. 14463-14477
    • Peng, F.1    Xiong, L.2    Tang, H.3    Peng, C.4    Chen, J.5
  • 5
    • 84870668442 scopus 로고    scopus 로고
    • The role of microRNAs in breast cancer migration, invasion and metastasis
    • Tang J, Ahmad A, Sarkar FH. The role of microRNAs in breast cancer migration, invasion and metastasis. Int J Mol Sci. 2012;13:13414–13437.
    • (2012) Int J Mol Sci , vol.13 , pp. 13414-13437
    • Tang, J.1    Ahmad, A.2    Sarkar, F.H.3
  • 6
    • 84924692295 scopus 로고    scopus 로고
    • Oleuropein induces apoptosis via activation of caspases and suppression of phosphatidylinositol 3-kinase/protein kinase B pathway in HepG2 human hepatoma cell line
    • Yan CM, Chai EQ, Cai HY, Miao GY, Ma W. Oleuropein induces apoptosis via activation of caspases and suppression of phosphatidylinositol 3-kinase/protein kinase B pathway in HepG2 human hepatoma cell line. Mol Med Rep. 2015;11:4617–4624.
    • (2015) Mol Med Rep , vol.11 , pp. 4617-4624
    • Yan, C.M.1    Chai, E.Q.2    Cai, H.Y.3    Miao, G.Y.4    Ma, W.5
  • 7
    • 85028947918 scopus 로고    scopus 로고
    • Aberrantly miRNA promoter methylation and EMT-involving miRNAs in breast cancer metastasis: diagnosis and therapeutic implications
    • Zare M, Bastami M, Solali S, Alivand M. Aberrantly miRNA promoter methylation and EMT-involving miRNAs in breast cancer metastasis: diagnosis and therapeutic implications. J Cell Physiol. 2017;233. https://doi.org/10.1002/jcp.26116
    • (2017) J Cell Physiol , vol.233
    • Zare, M.1    Bastami, M.2    Solali, S.3    Alivand, M.4
  • 8
    • 77955591555 scopus 로고    scopus 로고
    • MicroRNAs and their target gene networks in breast cancer
    • O'day E, Lal A. MicroRNAs and their target gene networks in breast cancer. Breast Cancer Res. 2010;12:201.
    • (2010) Breast Cancer Res , vol.12 , pp. 201
    • O'day, E.1    Lal, A.2
  • 9
    • 84958753183 scopus 로고    scopus 로고
    • Upregulation of the double-stranded RNA binding protein DGCR8 in invasive ductal breast carcinoma
    • Fardmanesh H, Shekari M, Movafagh A, et al. Upregulation of the double-stranded RNA binding protein DGCR8 in invasive ductal breast carcinoma. Gene. 2016;581:146–151.
    • (2016) Gene , vol.581 , pp. 146-151
    • Fardmanesh, H.1    Shekari, M.2    Movafagh, A.3
  • 11
    • 84988354525 scopus 로고    scopus 로고
    • Regulation of epithelial-mesenchymal transition through microRNAs: clinical and biological significance of microRNAs in breast cancer
    • Peng F, Xiong L, Tang H, Peng C, Chen J. Regulation of epithelial-mesenchymal transition through microRNAs: clinical and biological significance of microRNAs in breast cancer. Tumour Biol. 2016;37:14463–14477.
    • (2016) Tumour Biol , vol.37 , pp. 14463-14477
    • Peng, F.1    Xiong, L.2    Tang, H.3    Peng, C.4    Chen, J.5
  • 12
    • 84940211397 scopus 로고    scopus 로고
    • Simultaneous inhibition of multiple oncogenic miRNAs by a multi-potent microRNA sponge
    • Jung J, Yeom C, Al AE. Simultaneous inhibition of multiple oncogenic miRNAs by a multi-potent microRNA sponge. Oncotarget. 2015;6:18.
    • (2015) Oncotarget , vol.6 , pp. 18
    • Jung, J.1    Yeom, C.2    Al, A.E.3
  • 13
    • 84881322605 scopus 로고    scopus 로고
    • Regulating miRNA by natural agents as a new strategy for cancer treatment
    • Sethi S, Li Y, Sarkar FH. Regulating miRNA by natural agents as a new strategy for cancer treatment. Curr Drug Targets. 2013;14:1167–1174.
    • (2013) Curr Drug Targets , vol.14 , pp. 1167-1174
    • Sethi, S.1    Li, Y.2    Sarkar, F.H.3
  • 14
    • 84861212776 scopus 로고    scopus 로고
    • MicroRNA-34a and microRNA-21 play roles in the chemopreventive effects of 3,6-dihydroxyflavone on 1-methyl-1-nitrosourea-induced breast carcinogenesis
    • Hui C, Yujie F, Lijia Y, et al. MicroRNA-34a and microRNA-21 play roles in the chemopreventive effects of 3,6-dihydroxyflavone on 1-methyl-1-nitrosourea-induced breast carcinogenesis. Breast Cancer Res. 2012;14:R80.
    • (2012) Breast Cancer Res , vol.14 , pp. R80
    • Hui, C.1    Yujie, F.2    Lijia, Y.3
  • 15
    • 84938740283 scopus 로고    scopus 로고
    • Mango polyphenolics suppressed tumor growth in breast cancer xenografts in mice: role of the PI3K/AKT pathway and associated microRNAs
    • Banerjee N, Kim H, Krenek K, Talcott ST, Mertens-Talcott SU. Mango polyphenolics suppressed tumor growth in breast cancer xenografts in mice: role of the PI3K/AKT pathway and associated microRNAs. Nutr Res. 2015;35:744–751.
    • (2015) Nutr Res , vol.35 , pp. 744-751
    • Banerjee, N.1    Kim, H.2    Krenek, K.3    Talcott, S.T.4    Mertens-Talcott, S.U.5
  • 16
    • 85036644196 scopus 로고    scopus 로고
    • HDACis (class I), cancer stem cell, and phytochemicals: cancer therapy and prevention implications
    • Bayat S, Khaniani MS, Choupani J, Alivand MR, Derakhshan SM. HDACis (class I), cancer stem cell, and phytochemicals: cancer therapy and prevention implications. Biomed Pharmacother. 2018;97:1445–1453.
    • (2018) Biomed Pharmacother , vol.97 , pp. 1445-1453
    • Bayat, S.1    Khaniani, M.S.2    Choupani, J.3    Alivand, M.R.4    Derakhshan, S.M.5
  • 17
    • 77951228787 scopus 로고    scopus 로고
    • Qualitative screening of phenolic compounds in olive leaf extracts by hyphenated liquid chromatography and preliminary evaluation of cytotoxic activity against human breast cancer cells
    • Fu S, Arraez-Roman D, Segura-Carretero A, et al. Qualitative screening of phenolic compounds in olive leaf extracts by hyphenated liquid chromatography and preliminary evaluation of cytotoxic activity against human breast cancer cells. Anal Bioanal Chem. 2010;397:643–654.
    • (2010) Anal Bioanal Chem , vol.397 , pp. 643-654
    • Fu, S.1    Arraez-Roman, D.2    Segura-Carretero, A.3
  • 18
    • 17644420314 scopus 로고    scopus 로고
    • Scavenging of reactive oxygen species by the plant phenols genistein and oleuropein
    • Kruk I, Aboul-Enein HY, Michalska T, Lichszteld K, Kladna A. Scavenging of reactive oxygen species by the plant phenols genistein and oleuropein. Luminescence. 2005;20:81–89.
    • (2005) Luminescence , vol.20 , pp. 81-89
    • Kruk, I.1    Aboul-Enein, H.Y.2    Michalska, T.3    Lichszteld, K.4    Kladna, A.5
  • 19
    • 84908500692 scopus 로고    scopus 로고
    • Curcumin modulates miR-19/PTEN/AKT/p53 axis to suppress bisphenol A-induced MCF-7 breast cancer cell proliferation
    • Li X, Xie W, Xie C, et al. Curcumin modulates miR-19/PTEN/AKT/p53 axis to suppress bisphenol A-induced MCF-7 breast cancer cell proliferation. Phytother Res. 2014;28:1553–1560.
    • (2014) Phytother Res , vol.28 , pp. 1553-1560
    • Li, X.1    Xie, W.2    Xie, C.3
  • 20
    • 79951767903 scopus 로고    scopus 로고
    • Curcumin reduces the expression of Bcl-2 by upregulating miR-15a and miR-16 in MCF-7 cells
    • Yang J, Cao Y, Sun J, Zhang Y. Curcumin reduces the expression of Bcl-2 by upregulating miR-15a and miR-16 in MCF-7 cells. Med Oncol. 2010;27:1114–1118.
    • (2010) Med Oncol , vol.27 , pp. 1114-1118
    • Yang, J.1    Cao, Y.2    Sun, J.3    Zhang, Y.4
  • 21
    • 84855862393 scopus 로고    scopus 로고
    • Epigenetic events associated with breast cancer and their prevention by dietary components targeting the epigenome
    • Khan SI, Aumsuwan P, Khan IA, Walker LA, Dasmahapatra AK. Epigenetic events associated with breast cancer and their prevention by dietary components targeting the epigenome. Chem Res Toxicol. 2012;25:61–73.
    • (2012) Chem Res Toxicol , vol.25 , pp. 61-73
    • Khan, S.I.1    Aumsuwan, P.2    Khan, I.A.3    Walker, L.A.4    Dasmahapatra, A.K.5
  • 22
    • 84899152610 scopus 로고    scopus 로고
    • MiR181b is induced by the chemopreventive polyphenol curcumin and inhibits breast cancer metastasis via down-regulation of the inflammatory cytokines CXCL1 and −2
    • Kronski E, Fiori ME, Barbieri O, et al. MiR181b is induced by the chemopreventive polyphenol curcumin and inhibits breast cancer metastasis via down-regulation of the inflammatory cytokines CXCL1 and −2. Mol Oncol. 2014;8:581–595.
    • (2014) Mol Oncol , vol.8 , pp. 581-595
    • Kronski, E.1    Fiori, M.E.2    Barbieri, O.3
  • 23
    • 84867885344 scopus 로고    scopus 로고
    • Cytotoxicity of pomegranate polyphenolics in breast cancer cells in vitro and vivo: potential role of miRNA-27a and miRNA-155 in cell survival and inflammation
    • Banerjee N, Talcott S, Safe S, Mertens-Talcott SU. Cytotoxicity of pomegranate polyphenolics in breast cancer cells in vitro and vivo: potential role of miRNA-27a and miRNA-155 in cell survival and inflammation. Breast Cancer Res Treat. 2012;136:21–34.
    • (2012) Breast Cancer Res Treat , vol.136 , pp. 21-34
    • Banerjee, N.1    Talcott, S.2    Safe, S.3    Mertens-Talcott, S.U.4
  • 24
    • 84962660046 scopus 로고    scopus 로고
    • Silibinin-Induced apoptosis and downregulation of microRNA-21 and microRNA-155 in MCF-7 human breast cancer cells
    • Zadeh MM, Motamed N, Ranji N, Majidi M, Falahi F. Silibinin-Induced apoptosis and downregulation of microRNA-21 and microRNA-155 in MCF-7 human breast cancer cells. J Breast Cancer. 2016;19:45–52.
    • (2016) J Breast Cancer , vol.19 , pp. 45-52
    • Zadeh, M.M.1    Motamed, N.2    Ranji, N.3    Majidi, M.4    Falahi, F.5
  • 25
    • 84953407095 scopus 로고    scopus 로고
    • Deregulation of miR-21 and miR-155 and their putative targets after silibinin treatment in T47D breast cancer cells
    • Zadeh MM, Ranji N, Motamed N. Deregulation of miR-21 and miR-155 and their putative targets after silibinin treatment in T47D breast cancer cells. Iran J Basic Med Sci. 2015;18:1209–1214.
    • (2015) Iran J Basic Med Sci , vol.18 , pp. 1209-1214
    • Zadeh, M.M.1    Ranji, N.2    Motamed, N.3
  • 26
    • 84899926820 scopus 로고    scopus 로고
    • Oleuropein inhibits tumour growth and metastases dissemination in ovariectomised nude mice with MCF-7 human breast tumour xenografts
    • Sepporta MV, Fuccelli R, Rosignoli P, et al. Oleuropein inhibits tumour growth and metastases dissemination in ovariectomised nude mice with MCF-7 human breast tumour xenografts. J Funct Foods. 2014;8:269–273.
    • (2014) J Funct Foods , vol.8 , pp. 269-273
    • Sepporta, M.V.1    Fuccelli, R.2    Rosignoli, P.3
  • 27
    • 84874005412 scopus 로고    scopus 로고
    • Oleuropein induces anti-metastatic effects in breast cancer
    • Hassan ZK, Elamin MH, Daghestani MH, et al. Oleuropein induces anti-metastatic effects in breast cancer. Asian Pac J Cancer Prev. 2012;13:4555–4559.
    • (2012) Asian Pac J Cancer Prev , vol.13 , pp. 4555-4559
    • Hassan, Z.K.1    Elamin, M.H.2    Daghestani, M.H.3
  • 28
    • 84949293851 scopus 로고    scopus 로고
    • Oleuropein-Enriched olive leaf extract affects calcium dynamics and impairs viability of malignant mesothelioma cells
    • Marchetti C, Clericuzio M, Borghesi B, et al. Oleuropein-Enriched olive leaf extract affects calcium dynamics and impairs viability of malignant mesothelioma cells. Evid Based Complement Alternat Med. 2015;2015:908493.
    • (2015) Evid Based Complement Alternat Med , vol.2015 , pp. 908493
    • Marchetti, C.1    Clericuzio, M.2    Borghesi, B.3
  • 29
    • 84963699422 scopus 로고    scopus 로고
    • Investigation of anticancer mechanism of oleuropein via cell cycle and apoptotic pathways in SH-SY5Y neuroblastoma cells
    • Secme M, Eroglu C, Dodurga Y, Bagci G. Investigation of anticancer mechanism of oleuropein via cell cycle and apoptotic pathways in SH-SY5Y neuroblastoma cells. Gene. 2016;585:93–99.
    • (2016) Gene , vol.585 , pp. 93-99
    • Secme, M.1    Eroglu, C.2    Dodurga, Y.3    Bagci, G.4
  • 30
    • 84923529048 scopus 로고    scopus 로고
    • Olea europaea leaf extract improves the treatment response of GBM stem cells by modulating miRNA expression
    • Tezcan G, Tunca B, Bekar A, et al. Olea europaea leaf extract improves the treatment response of GBM stem cells by modulating miRNA expression. Am J Cancer Res. 2014;4:572–590.
    • (2014) Am J Cancer Res , vol.4 , pp. 572-590
    • Tezcan, G.1    Tunca, B.2    Bekar, A.3
  • 31
    • 84892458129 scopus 로고    scopus 로고
    • Oleuropein induces apoptosis via the p53 pathway in breast cancer cells
    • Hassan ZK, Elamin MH, Omer SA, et al. Oleuropein induces apoptosis via the p53 pathway in breast cancer cells. Asian Pac J Cancer Prev. 2014;14:6739–6742.
    • (2014) Asian Pac J Cancer Prev , vol.14 , pp. 6739-6742
    • Hassan, Z.K.1    Elamin, M.H.2    Omer, S.A.3
  • 32
    • 33751275468 scopus 로고    scopus 로고
    • (2Alpha,3beta)-2,3-dihydroxyolean-12-en-28-oic acid, a new natural triterpene from Olea europea, induces caspase dependent apoptosis selectively in colon adenocarcinoma cells
    • Reyes FJ, Centelles JJ, Lupianez JA, Cascante M. (2Alpha,3beta)-2,3-dihydroxyolean-12-en-28-oic acid, a new natural triterpene from Olea europea, induces caspase dependent apoptosis selectively in colon adenocarcinoma cells. FEBS Lett. 2006;580:6302–6310.
    • (2006) FEBS Lett , vol.580 , pp. 6302-6310
    • Reyes, F.J.1    Centelles, J.J.2    Lupianez, J.A.3    Cascante, M.4
  • 33
    • 67349201394 scopus 로고    scopus 로고
    • Anti-proliferative and apoptotic effects of oleuropein and hydroxytyrosol on human breast cancer MCF-7 cells
    • Han J, Talorete TP, Yamada P, Isoda H. Anti-proliferative and apoptotic effects of oleuropein and hydroxytyrosol on human breast cancer MCF-7 cells. Cytotechnology. 2009;59:45–53.
    • (2009) Cytotechnology , vol.59 , pp. 45-53
    • Han, J.1    Talorete, T.P.2    Yamada, P.3    Isoda, H.4
  • 35
    • 84958779478 scopus 로고    scopus 로고
    • MiR-21 might be involved in breast cancer promotion and invasion rather than in initial events of breast cancer development
    • Petrovic N. MiR-21 might be involved in breast cancer promotion and invasion rather than in initial events of breast cancer development. Mol Diagn Ther. 2016;20:97–110.
    • (2016) Mol Diagn Ther , vol.20 , pp. 97-110
    • Petrovic, N.1
  • 36
    • 0142025131 scopus 로고    scopus 로고
    • Loss of expression of tropomyosin-1, a novel class II tumor suppressor that induces anoikis, in primary breast tumors
    • Raval GN, Bharadwaj S, Levine EA, et al. Loss of expression of tropomyosin-1, a novel class II tumor suppressor that induces anoikis, in primary breast tumors. Oncogene. 2003;22:6194–6203.
    • (2003) Oncogene , vol.22 , pp. 6194-6203
    • Raval, G.N.1    Bharadwaj, S.2    Levine, E.A.3
  • 37
    • 34347266556 scopus 로고    scopus 로고
    • MicroRNA-21 targets the tumor suppressor gene tropomyosin 1 (TPM1)
    • Zhu S, Si ML, Wu H, Mo YY. MicroRNA-21 targets the tumor suppressor gene tropomyosin 1 (TPM1). J Biol Chem. 2007;282:14328–14336.
    • (2007) J Biol Chem , vol.282 , pp. 14328-14336
    • Zhu, S.1    Si, M.L.2    Wu, H.3    Mo, Y.Y.4
  • 38
    • 84961762733 scopus 로고    scopus 로고
    • Expression of tropomyosin 1 gene isoforms in human Breast cancer cell lines
    • Dube S, Yalamanchili S, Lachant J, et al. Expression of tropomyosin 1 gene isoforms in human Breast cancer cell lines. Int J Breast Cancer. 2015;2015:859427.
    • (2015) Int J Breast Cancer , vol.2015 , pp. 859427
    • Dube, S.1    Yalamanchili, S.2    Lachant, J.3
  • 39
    • 84949770766 scopus 로고    scopus 로고
    • MiRNA-21 induces epithelial to mesenchymal transition and gemcitabine resistance via the PTEN/AKT pathway in breast cancer
    • Wu ZH, Tao ZH, Zhang J, et al. MiRNA-21 induces epithelial to mesenchymal transition and gemcitabine resistance via the PTEN/AKT pathway in breast cancer. Tumour Biol. 2016;37:7245–7254.
    • (2016) Tumour Biol , vol.37 , pp. 7245-7254
    • Wu, Z.H.1    Tao, Z.H.2    Zhang, J.3
  • 40
    • 84947808033 scopus 로고    scopus 로고
    • MicroRNA-21 links epithelial-to-mesenchymal transition and inflammatory signals to confer resistance to neoadjuvant trastuzumab and chemotherapy in HER2-positive breast cancer patients
    • DE Mattos-Arruda L, Bottai G, Nuciforo PG, et al. MicroRNA-21 links epithelial-to-mesenchymal transition and inflammatory signals to confer resistance to neoadjuvant trastuzumab and chemotherapy in HER2-positive breast cancer patients. Oncotarget. 2015;6:37269–37280.
    • (2015) Oncotarget , vol.6 , pp. 37269-37280
    • DE Mattos-Arruda, L.1    Bottai, G.2    Nuciforo, P.G.3
  • 41
    • 67649783639 scopus 로고    scopus 로고
    • Expression of miR-21 and its targets (PTEN, PDCD4, TM1) in flat epithelial atypia of the breast in relation to ductal carcinoma in situ and invasive carcinoma
    • Qi L, Bart J, Tan LP, et al. Expression of miR-21 and its targets (PTEN, PDCD4, TM1) in flat epithelial atypia of the breast in relation to ductal carcinoma in situ and invasive carcinoma. BMC Cancer. 2009;9:163.
    • (2009) BMC Cancer , vol.9 , pp. 163
    • Qi, L.1    Bart, J.2    Tan, L.P.3
  • 42
    • 84862638243 scopus 로고    scopus 로고
    • Antagonism of miR-21 reverses epithelial-mesenchymal transition and cancer stem cell phenotype through AKT/ERK1/2 inactivation by targeting PTEN
    • Han M, Liu M, Wang Y, et al. Antagonism of miR-21 reverses epithelial-mesenchymal transition and cancer stem cell phenotype through AKT/ERK1/2 inactivation by targeting PTEN. PLoS ONE. 2012;7:e39520.
    • (2012) PLoS ONE , vol.7
    • Han, M.1    Liu, M.2    Wang, Y.3
  • 43
    • 79959315095 scopus 로고    scopus 로고
    • Apoptosis and the target genes of microRNA-21
    • Buscaglia LEB, Li Y. Apoptosis and the target genes of microRNA-21. Chin J Cancer. 2011;30:371.
    • (2011) Chin J Cancer , vol.30 , pp. 371
    • Buscaglia, L.E.B.1    Li, Y.2
  • 44
    • 84863906869 scopus 로고    scopus 로고
    • MicroRNAs as therapeutic targets and their potential applications in cancer therapy
    • Cho WC. MicroRNAs as therapeutic targets and their potential applications in cancer therapy. Expert Opin Ther Targets. 2012;16:747–759.
    • (2012) Expert Opin Ther Targets , vol.16 , pp. 747-759
    • Cho, W.C.1
  • 45
    • 84991697234 scopus 로고    scopus 로고
    • RECK impedes DNA repair by inhibiting the erbB/JAB1/Rad51 signaling axis and enhances chemosensitivity of breast cancer cells
    • Hong KJ, Hsu MC, Hung WC. RECK impedes DNA repair by inhibiting the erbB/JAB1/Rad51 signaling axis and enhances chemosensitivity of breast cancer cells. Am J Cancer Res. 2015;5:2422–2430.
    • (2015) Am J Cancer Res , vol.5 , pp. 2422-2430
    • Hong, K.J.1    Hsu, M.C.2    Hung, W.C.3
  • 46
    • 84926325503 scopus 로고    scopus 로고
    • Ras induces experimental lung metastasis through up-regulation of RbAp46 to suppress RECK promoter activity
    • Yeh HH, Tseng YF, Hsu YC, et al. Ras induces experimental lung metastasis through up-regulation of RbAp46 to suppress RECK promoter activity. BMC Cancer. 2015;15:172.
    • (2015) BMC Cancer , vol.15 , pp. 172
    • Yeh, H.H.1    Tseng, Y.F.2    Hsu, Y.C.3
  • 47
    • 84954539912 scopus 로고    scopus 로고
    • Silencing of MicroRNA-21 confers the sensitivity to tamoxifen and fulvestrant by enhancing autophagic cell death through inhibition of the PI3K-AKT-mTOR pathway in breast cancer cells
    • Yu X, Li R, Shi W, et al. Silencing of MicroRNA-21 confers the sensitivity to tamoxifen and fulvestrant by enhancing autophagic cell death through inhibition of the PI3K-AKT-mTOR pathway in breast cancer cells. Biomed Pharmacother. 2016;77:37–44.
    • (2016) Biomed Pharmacother , vol.77 , pp. 37-44
    • Yu, X.1    Li, R.2    Shi, W.3
  • 48
    • 84939889685 scopus 로고    scopus 로고
    • RECK controls breast cancer metastasis by modulating a convergent, STAT3-dependent neoangiogenic switch
    • Walsh LA, Roy DM, Reyngold M, et al. RECK controls breast cancer metastasis by modulating a convergent, STAT3-dependent neoangiogenic switch. Oncogene. 2015;34:2189–2203.
    • (2015) Oncogene , vol.34 , pp. 2189-2203
    • Walsh, L.A.1    Roy, D.M.2    Reyngold, M.3
  • 49
    • 77950905590 scopus 로고    scopus 로고
    • MicroRNA-21 regulates breast cancer invasion partly by targeting tissue inhibitor of metalloproteinase 3 expression
    • Song B, Wang C, Liu J, et al. MicroRNA-21 regulates breast cancer invasion partly by targeting tissue inhibitor of metalloproteinase 3 expression. J Exp Clin Cancer Res. 2010;29:29.
    • (2010) J Exp Clin Cancer Res , vol.29 , pp. 29
    • Song, B.1    Wang, C.2    Liu, J.3
  • 50
    • 84876465381 scopus 로고    scopus 로고
    • MicroRNA-155 is a novel suppressor of ovarian cancer-initiating cells that targets CLDN1
    • Qin W, Ren Q, Liu T, Huang Y, Wang J. MicroRNA-155 is a novel suppressor of ovarian cancer-initiating cells that targets CLDN1. FEBS Lett. 2013;587:1434–1439.
    • (2013) FEBS Lett , vol.587 , pp. 1434-1439
    • Qin, W.1    Ren, Q.2    Liu, T.3    Huang, Y.4    Wang, J.5
  • 51
    • 84886055056 scopus 로고    scopus 로고
    • MiR-155 promotes proliferation of human breast cancer MCF-7 cells through targeting tumor protein 53-induced nuclear protein 1
    • Zhang CM, Zhao J, Deng HY. MiR-155 promotes proliferation of human breast cancer MCF-7 cells through targeting tumor protein 53-induced nuclear protein 1. J Biomed Sci. 2013;20:79.
    • (2013) J Biomed Sci , vol.20 , pp. 79
    • Zhang, C.M.1    Zhao, J.2    Deng, H.Y.3
  • 52
    • 77952944048 scopus 로고    scopus 로고
    • MicroRNA-155 regulates cell survival, growth, and chemosensitivity by targeting FOXO3a in breast cancer
    • Kong W, He L, Coppola M, et al. MicroRNA-155 regulates cell survival, growth, and chemosensitivity by targeting FOXO3a in breast cancer. J Biol Chem. 2010;285:17869–17879.
    • (2010) J Biol Chem , vol.285 , pp. 17869-17879
    • Kong, W.1    He, L.2    Coppola, M.3
  • 53
    • 85029052852 scopus 로고    scopus 로고
    • Pharmacological activation of FOXO3 suppresses triple-negative breast cancer in vitro and in vivo
    • Park SH, Chung YM, Ma J, Yang Q, Berek JS, Hu MC. Pharmacological activation of FOXO3 suppresses triple-negative breast cancer in vitro and in vivo. Oncotarget. 2016;7:42110–42125.
    • (2016) Oncotarget , vol.7 , pp. 42110-42125
    • Park, S.H.1    Chung, Y.M.2    Ma, J.3    Yang, Q.4    Berek, J.S.5    Hu, M.C.6
  • 54
    • 76749087353 scopus 로고    scopus 로고
    • CBFA2T3-ZNF651, like CBFA2T3-ZNF 652, functions as a transcriptional corepressor complex
    • Kumar R, Cheney KM, Al E. CBFA2T3-ZNF651, like CBFA2T3-ZNF 652, functions as a transcriptional corepressor complex. FEBS Lett. 2010;584:859–864.
    • (2010) FEBS Lett , vol.584 , pp. 859-864
    • Kumar, R.1    Cheney, K.M.2    Al, E.3
  • 55
    • 84885386910 scopus 로고    scopus 로고
    • Regulation of the MIR155 host gene in physiological and pathological processes
    • Elton TS, Selemon H, Elton SM, Parinandi NL. Regulation of the MIR155 host gene in physiological and pathological processes. Gene. 2013;532:1–12.
    • (2013) Gene , vol.532 , pp. 1-12
    • Elton, T.S.1    Selemon, H.2    Elton, S.M.3    Parinandi, N.L.4
  • 56
    • 84923078124 scopus 로고    scopus 로고
    • TGF-beta1 acts through miR-155 to down-regulate TP53INP1 in promoting epithelial-mesenchymal transition and cancer stem cell phenotypes
    • Liu F, Kong X, Lv L, Gao J. TGF-beta1 acts through miR-155 to down-regulate TP53INP1 in promoting epithelial-mesenchymal transition and cancer stem cell phenotypes. Cancer Lett. 2015;359:288–298.
    • (2015) Cancer Lett , vol.359 , pp. 288-298
    • Liu, F.1    Kong, X.2    Lv, L.3    Gao, J.4
  • 57
    • 84878467113 scopus 로고    scopus 로고
    • 17beta-estradiol up-regulates miR-155 expression and reduces TP53INP1 expression in MCF-7 breast cancer cells
    • Zhang C, Zhao J, Deng H. 17beta-estradiol up-regulates miR-155 expression and reduces TP53INP1 expression in MCF-7 breast cancer cells. Mol Cell Biochem. 2013;379:201–211.
    • (2013) Mol Cell Biochem , vol.379 , pp. 201-211
    • Zhang, C.1    Zhao, J.2    Deng, H.3
  • 58
    • 33845959905 scopus 로고    scopus 로고
    • Decreased expression of tumor protein p53-induced nuclear protein 1 (TP53INP1) in breast carcinoma
    • Ito Y, Motoo Y, Yoshida H, et al. Decreased expression of tumor protein p53-induced nuclear protein 1 (TP53INP1) in breast carcinoma. Anticancer Res. 2006;26:4391–4395.
    • (2006) Anticancer Res , vol.26 , pp. 4391-4395
    • Ito, Y.1    Motoo, Y.2    Yoshida, H.3
  • 59
    • 79951803234 scopus 로고    scopus 로고
    • MiR-21 downregulates the tumor suppressor P12CDK2AP1 and Stimulates Cell Proliferation and Invasion
    • Zheng J, Xue H, Wang T, et al. MiR-21 downregulates the tumor suppressor P12CDK2AP1 and Stimulates Cell Proliferation and Invasion. J Cell Biochem. 2011;112:872–880.
    • (2011) J Cell Biochem , vol.112 , pp. 872-880
    • Zheng, J.1    Xue, H.2    Wang, T.3
  • 60
    • 84954357767 scopus 로고    scopus 로고
    • Effect of miR-155 knockdown on the reversal of doxorubicin resistance in human lung cancer A549/dox cells
    • Lixia LV, Xiumei AN, Al AE. Effect of miR-155 knockdown on the reversal of doxorubicin resistance in human lung cancer A549/dox cells. Oncol Lett. 2016;11:1161–1166.
    • (2016) Oncol Lett , vol.11 , pp. 1161-1166
    • Lixia, L.V.1    Xiumei, A.N.2    Al, A.E.3
  • 61
    • 84873647838 scopus 로고    scopus 로고
    • Phytoalexins, miRNAs and breast cancer: a review of phytochemical-mediated miRNA regulation in breast cancer
    • Tilghman SL, Rhodes LV, Bratton MR, et al. Phytoalexins, miRNAs and breast cancer: a review of phytochemical-mediated miRNA regulation in breast cancer. J Health Care Poor Underserved. 2013;24:36–46.
    • (2013) J Health Care Poor Underserved , vol.24 , pp. 36-46
    • Tilghman, S.L.1    Rhodes, L.V.2    Bratton, M.R.3
  • 62
    • 75949106927 scopus 로고    scopus 로고
    • Downregulation of miR-21 inhibits EGFR pathway and suppresses the growth of human glioblastoma cells independent of PTEN status
    • Zhou X, Ren Y, Moore L, et al. Downregulation of miR-21 inhibits EGFR pathway and suppresses the growth of human glioblastoma cells independent of PTEN status. Lab Invest. 2010;90:144–155.
    • (2010) Lab Invest , vol.90 , pp. 144-155
    • Zhou, X.1    Ren, Y.2    Moore, L.3
  • 63
    • 22744447495 scopus 로고    scopus 로고
    • Oleuropein, a non-toxic olive iridoid, is an anti-tumor agent and cytoskeleton disruptor
    • Hamdi HK, Castellon R. Oleuropein, a non-toxic olive iridoid, is an anti-tumor agent and cytoskeleton disruptor. Biochem Biophys Res Commun. 2005;334:769–778.
    • (2005) Biochem Biophys Res Commun , vol.334 , pp. 769-778
    • Hamdi, H.K.1    Castellon, R.2
  • 64
    • 84872236024 scopus 로고    scopus 로고
    • Olive oil oleuropein has anti-breast cancer properties with higher efficiency on ER-negative cells
    • Elamin MH, Daghestani MH, Omer SA, et al. Olive oil oleuropein has anti-breast cancer properties with higher efficiency on ER-negative cells. Food Chem Toxicol. 2013;53:310–316.
    • (2013) Food Chem Toxicol , vol.53 , pp. 310-316
    • Elamin, M.H.1    Daghestani, M.H.2    Omer, S.A.3
  • 65
    • 85017136677 scopus 로고    scopus 로고
    • The prognostic and therapeutic application of microRNAs in breast cancer: tissue and circulating microRNAs
    • Bahrami A, Aledavood A, Anvari K, et al. The prognostic and therapeutic application of microRNAs in breast cancer: tissue and circulating microRNAs. J Cell Physiol. 2018;233:774–786.
    • (2018) J Cell Physiol , vol.233 , pp. 774-786
    • Bahrami, A.1    Aledavood, A.2    Anvari, K.3
  • 66
    • 84985011714 scopus 로고    scopus 로고
    • Oleuropein inhibits the proliferation and invasion of glioma cells via suppression of the AKT signaling pathway
    • Liu M, Wang J, Huang B, Chen A, Li X. Oleuropein inhibits the proliferation and invasion of glioma cells via suppression of the AKT signaling pathway. Oncol Rep. 2016;36:2009–2016.
    • (2016) Oncol Rep , vol.36 , pp. 2009-2016
    • Liu, M.1    Wang, J.2    Huang, B.3    Chen, A.4    Li, X.5
  • 67
    • 84922562352 scopus 로고    scopus 로고
    • MiR-21 and let-7 in the Ras and NF-κB Pathways
    • Choudhury SN, Li Y. MiR-21 and let-7 in the Ras and NF-κB Pathways. Microrna. 2012;1:65–69.
    • (2012) Microrna , vol.1 , pp. 65-69
    • Choudhury, S.N.1    Li, Y.2
  • 70
    • 33947693893 scopus 로고    scopus 로고
    • Loss of APAF-1 expression is associated with tumour progression and adverse prognosis in colorectal cancer
    • Zlobec I, Minoo P, Baker K, et al. Loss of APAF-1 expression is associated with tumour progression and adverse prognosis in colorectal cancer. Eur J Cancer. 2007;43:1101–1107.
    • (2007) Eur J Cancer , vol.43 , pp. 1101-1107
    • Zlobec, I.1    Minoo, P.2    Baker, K.3
  • 71
    • 18144426785 scopus 로고    scopus 로고
    • Expression of Apaf-1 in cervical cancer correlates with lymph node metastasis but not with intratumoral hypoxia
    • Leo C, Richter C, Horn L-C, Schutz A, Pilch H, Höckel M. Expression of Apaf-1 in cervical cancer correlates with lymph node metastasis but not with intratumoral hypoxia. Gynecol Oncol. 2005;97:602–606.
    • (2005) Gynecol Oncol , vol.97 , pp. 602-606
    • Leo, C.1    Richter, C.2    Horn, L.-C.3    Schutz, A.4    Pilch, H.5    Höckel, M.6
  • 72
    • 84892919523 scopus 로고    scopus 로고
    • MicroRNA-23a antisense enhances 5-fluorouracil chemosensitivity through APAF-1/caspase-9 apoptotic pathway in colorectal cancer cells
    • Shang J, Yang F, Wang Y, et al. MicroRNA-23a antisense enhances 5-fluorouracil chemosensitivity through APAF-1/caspase-9 apoptotic pathway in colorectal cancer cells. J Cell Biochem. 2014;115:772–784.
    • (2014) J Cell Biochem , vol.115 , pp. 772-784
    • Shang, J.1    Yang, F.2    Wang, Y.3
  • 73
    • 84862815471 scopus 로고    scopus 로고
    • Caspase-mediated programmed cell death pathways as potential therapeutic targets in cancer
    • Wen X, Lin ZQ, Liu B, Wei YQ. Caspase-mediated programmed cell death pathways as potential therapeutic targets in cancer. Cell Prolif. 2012;45:217–224.
    • (2012) Cell Prolif , vol.45 , pp. 217-224
    • Wen, X.1    Lin, Z.Q.2    Liu, B.3    Wei, Y.Q.4
  • 74
    • 84864090039 scopus 로고    scopus 로고
    • Matrine inhibits breast cancer growth via miR-21/PTEN/Akt pathway in MCF-7 cells
    • Li L-Q, Li X-L, Wang L, et al. Matrine inhibits breast cancer growth via miR-21/PTEN/Akt pathway in MCF-7 cells. Cell Physiol Biochem. 2012;30:631–641.
    • (2012) Cell Physiol Biochem , vol.30 , pp. 631-641
    • Li, L.-Q.1    Li, X.-L.2    Wang, L.3
  • 75
    • 77956061393 scopus 로고    scopus 로고
    • MicroRNA-21 (miR-21) represses tumor suppressor PTEN and promotes growth and invasion in non-small cell lung cancer (NSCLC)
    • Zhang J-G, Wang J-J, Zhao F, Liu Q, Jiang K, Yang G-H. MicroRNA-21 (miR-21) represses tumor suppressor PTEN and promotes growth and invasion in non-small cell lung cancer (NSCLC). Clin Chim Acta. 2010;411:846–852.
    • (2010) Clin Chim Acta , vol.411 , pp. 846-852
    • Zhang, J.-G.1    Wang, J.-J.2    Zhao, F.3    Liu, Q.4    Jiang, K.5    Yang, G.-H.6
  • 76
    • 0034891004 scopus 로고    scopus 로고
    • P53DINP1, a p53-inducible gene, regulates p53-dependent apoptosis
    • Okamura S, Arakawa H, Tanaka T, et al. P53DINP1, a p53-inducible gene, regulates p53-dependent apoptosis. Mol Cell. 2001;8:85–94.
    • (2001) Mol Cell , vol.8 , pp. 85-94
    • Okamura, S.1    Arakawa, H.2    Tanaka, T.3
  • 77
    • 84892458129 scopus 로고    scopus 로고
    • Oleuropein induces apoptosis via the p53 pathway in breast cancer cells
    • Hassan ZK, Elamin MH, Omer SA, et al. Oleuropein induces apoptosis via the p53 pathway in breast cancer cells. Asian Pac J Cancer Prev. 2013;14:6739–6742.
    • (2013) Asian Pac J Cancer Prev , vol.14 , pp. 6739-6742
    • Hassan, Z.K.1    Elamin, M.H.2    Omer, S.A.3
  • 78
    • 80053954562 scopus 로고    scopus 로고
    • A novel kinase inhibitor of FADD phosphorylation chemosensitizes through the inhibition of NF-kappaB
    • Schinske KA, Nyati S, Khan AP, et al. A novel kinase inhibitor of FADD phosphorylation chemosensitizes through the inhibition of NF-kappaB. Mol Cancer Ther. 2011;10:1807–1817.
    • (2011) Mol Cancer Ther , vol.10 , pp. 1807-1817
    • Schinske, K.A.1    Nyati, S.2    Khan, A.P.3
  • 79
    • 84977151270 scopus 로고    scopus 로고
    • Copy number and expression analysis of FOSL1, GSTP1, NTSR1, FADD and CCND1 genes in primary breast tumors with axillary lymph node metastasis
    • Callegari CC, Cavalli IJ, Lima RS, et al. Copy number and expression analysis of FOSL1, GSTP1, NTSR1, FADD and CCND1 genes in primary breast tumors with axillary lymph node metastasis. Cancer Genet. 2016;209:331–339.
    • (2016) Cancer Genet , vol.209 , pp. 331-339
    • Callegari, C.C.1    Cavalli, I.J.2    Lima, R.S.3
  • 80
    • 80052460614 scopus 로고    scopus 로고
    • Deregulated miR-155 promotes Fas-mediated apoptosis in human intervertebral disc degeneration by targeting FADD and caspase-3
    • Wang HQ, Yu XD, Liu ZH, et al. Deregulated miR-155 promotes Fas-mediated apoptosis in human intervertebral disc degeneration by targeting FADD and caspase-3. J Pathol. 2011;225:232–242.
    • (2011) J Pathol , vol.225 , pp. 232-242
    • Wang, H.Q.1    Yu, X.D.2    Liu, Z.H.3
  • 82
    • 85012878364 scopus 로고    scopus 로고
    • MicroRNA-21 regulates the ERK/NF-kappaB signaling pathway to affect the proliferation, migration, and apoptosis of human melanoma A375 cells by targeting SPRY1, PDCD4, and PTEN
    • Mao XH, Chen M, Wang Y, Cui PG, Liu SB, Xu ZY. MicroRNA-21 regulates the ERK/NF-kappaB signaling pathway to affect the proliferation, migration, and apoptosis of human melanoma A375 cells by targeting SPRY1, PDCD4, and PTEN. Mol Carcinog. 2017;56:886–894.
    • (2017) Mol Carcinog , vol.56 , pp. 886-894
    • Mao, X.H.1    Chen, M.2    Wang, Y.3    Cui, P.G.4    Liu, S.B.5    Xu, Z.Y.6
  • 83
    • 80155151231 scopus 로고    scopus 로고
    • An integrative genomic analysis revealed the relevance of microRNA and gene expression for drug-resistance in human breast cancer cells
    • Yamamoto Y, Yoshioka Y, Minoura K, et al. An integrative genomic analysis revealed the relevance of microRNA and gene expression for drug-resistance in human breast cancer cells. Mol Cancer. 2011;10:135.
    • (2011) Mol Cancer , vol.10 , pp. 135
    • Yamamoto, Y.1    Yoshioka, Y.2    Minoura, K.3
  • 84
    • 79959843370 scopus 로고    scopus 로고
    • MicroRNA-21 targets tumor suppressor genes ANP32A and SMARCA4
    • Schramedei K, Mörbt N, Pfeifer G, et al. MicroRNA-21 targets tumor suppressor genes ANP32A and SMARCA4. Oncogene. 2011;30:2975–2985.
    • (2011) Oncogene , vol.30 , pp. 2975-2985
    • Schramedei, K.1    Mörbt, N.2    Pfeifer, G.3
  • 85
    • 42249090353 scopus 로고    scopus 로고
    • MiR-21 Gene expression triggered by AP-1 is sustained through a double-negative feedback mechanism
    • Fujita S, Ito T, Mizutani T, et al. MiR-21 Gene expression triggered by AP-1 is sustained through a double-negative feedback mechanism. J Mol Biol. 2008;378:492–504.
    • (2008) J Mol Biol , vol.378 , pp. 492-504
    • Fujita, S.1    Ito, T.2    Mizutani, T.3
  • 86
    • 54249136806 scopus 로고    scopus 로고
    • MicroRNA-21 targets a network of key tumor-suppressive pathways in glioblastoma cells
    • Papagiannakopoulos T, Shapiro A, Kosik KS. MicroRNA-21 targets a network of key tumor-suppressive pathways in glioblastoma cells. Cancer Res. 2008;68:8164–8172.
    • (2008) Cancer Res , vol.68 , pp. 8164-8172
    • Papagiannakopoulos, T.1    Shapiro, A.2    Kosik, K.S.3
  • 87
    • 68149137764 scopus 로고    scopus 로고
    • Regulation of the cell cycle gene, BTG2, by miR-21 in human laryngeal carcinoma
    • Liu M, Wu H, Liu T, et al. Regulation of the cell cycle gene, BTG2, by miR-21 in human laryngeal carcinoma. Cell Res. 2009;19:828–837.
    • (2009) Cell Res , vol.19 , pp. 828-837
    • Liu, M.1    Wu, H.2    Liu, T.3
  • 88
    • 77952948062 scopus 로고    scopus 로고
    • Overexpression of miR-21 promotes an in vitro metastatic phenotype by targeting the tumor suppressor RHOB
    • Connolly EC, Van Doorslaer K, Rogler LE, Rogler CE. Overexpression of miR-21 promotes an in vitro metastatic phenotype by targeting the tumor suppressor RHOB. Mol Cancer Res. 2010;8:691–700.
    • (2010) Mol Cancer Res , vol.8 , pp. 691-700
    • Connolly, E.C.1    Van Doorslaer, K.2    Rogler, L.E.3    Rogler, C.E.4
  • 89
    • 84919474075 scopus 로고    scopus 로고
    • Disruption of microRNA-21 by TALEN leads to diminished cell transformation and increased expression of cell-environment interaction genes
    • Chen B, Chen X, Wu X, et al. Disruption of microRNA-21 by TALEN leads to diminished cell transformation and increased expression of cell-environment interaction genes. Cancer Lett. 2015;356:506–516.
    • (2015) Cancer Lett , vol.356 , pp. 506-516
    • Chen, B.1    Chen, X.2    Wu, X.3
  • 91
    • 55549120234 scopus 로고    scopus 로고
    • MicroRNA miR-21 overexpression in human breast cancer is associated with advanced clinical stage, lymph node metastasis and patient poor prognosis
    • Yan L-X, Huang X-F, Shao Q, et al. MicroRNA miR-21 overexpression in human breast cancer is associated with advanced clinical stage, lymph node metastasis and patient poor prognosis. RNA. 2008;14:2348–2360.
    • (2008) RNA , vol.14 , pp. 2348-2360
    • Yan, L.-X.1    Huang, X.-F.2    Shao, Q.3
  • 92
    • 84861474291 scopus 로고    scopus 로고
    • MiR-21 may acts as an oncomir by targeting RECK, a matrix metalloproteinase regulator, in prostate cancer
    • Reis ST, Pontes-Junior J, Antunes AA, et al. MiR-21 may acts as an oncomir by targeting RECK, a matrix metalloproteinase regulator, in prostate cancer. BMC Urol. 2012;12:14.
    • (2012) BMC Urol , vol.12 , pp. 14
    • Reis, S.T.1    Pontes-Junior, J.2    Antunes, A.A.3
  • 93
    • 84872743484 scopus 로고    scopus 로고
    • Subsite-based alterations in miR-21, miR-125b, and miR-203 in squamous cell carcinoma of the oral cavity and correlation to important target proteins
    • Boldrup L, Coates PJ, Wahlgren M, Laurell G, Nylander K. Subsite-based alterations in miR-21, miR-125b, and miR-203 in squamous cell carcinoma of the oral cavity and correlation to important target proteins. J Carcinog. 2012;11:18–25.
    • (2012) J Carcinog , vol.11 , pp. 18-25
    • Boldrup, L.1    Coates, P.J.2    Wahlgren, M.3    Laurell, G.4    Nylander, K.5
  • 94
    • 84859389554 scopus 로고    scopus 로고
    • Downregulation of inflammatory microRNAs by Ig-like transcript 3 is essential for the differentiation of human CD8+ T suppressor cells
    • Chang C-C, Zhang Q-Y, Liu Z, Clynes RA, Suciu-Foca N, Vlad G. Downregulation of inflammatory microRNAs by Ig-like transcript 3 is essential for the differentiation of human CD8+ T suppressor cells. J Immunol. 2012;188:3042–3052.
    • (2012) J Immunol , vol.188 , pp. 3042-3052
    • Chang, C.-C.1    Zhang, Q.-Y.2    Liu, Z.3    Clynes, R.A.4    Suciu-Foca, N.5    Vlad, G.6
  • 95
    • 83555171758 scopus 로고    scopus 로고
    • Knockdown of miR-21 in human breast cancer cell lines inhibits proliferation, in vitro migration and in vivo tumor growth
    • Yan LX, Wu QN, Zhang Y, et al. Knockdown of miR-21 in human breast cancer cell lines inhibits proliferation, in vitro migration and in vivo tumor growth. Breast Cancer Res. 2011;13:R2.
    • (2011) Breast Cancer Res , vol.13 , pp. R2
    • Yan, L.X.1    Wu, Q.N.2    Zhang, Y.3
  • 96
    • 84859594480 scopus 로고    scopus 로고
    • Identification of novel miR-21 target proteins in multiple myeloma cells by quantitative proteomics
    • Xiong Q, Zhong Q, Zhang J, et al. Identification of novel miR-21 target proteins in multiple myeloma cells by quantitative proteomics. J Proteome Res. 2012;11:2078–2090.
    • (2012) J Proteome Res , vol.11 , pp. 2078-2090
    • Xiong, Q.1    Zhong, Q.2    Zhang, J.3
  • 97
    • 84952031873 scopus 로고    scopus 로고
    • MiR-21 promotes renal fibrosis in diabetic nephropathy by targeting PTEN and SMAD7
    • Mcclelland AD, Herman-Edelstein M, Komers R, et al. MiR-21 promotes renal fibrosis in diabetic nephropathy by targeting PTEN and SMAD7. Clin Sci. 2015;129:1237–1249.
    • (2015) Clin Sci , vol.129 , pp. 1237-1249
    • Mcclelland, A.D.1    Herman-Edelstein, M.2    Komers, R.3
  • 98
    • 73349136775 scopus 로고    scopus 로고
    • MiR-155: on the crosstalk between inflammation and cancer
    • Tili E, Croce CM, Michaille J-J. MiR-155: on the crosstalk between inflammation and cancer. In Rev Immunol. 2009;28:264–284.
    • (2009) In Rev Immunol , vol.28 , pp. 264-284
    • Tili, E.1    Croce, C.M.2    Michaille, J.-J.3
  • 99
    • 84876584007 scopus 로고    scopus 로고
    • MiR-155 regulates immune modulatory properties of mesenchymal stem cells by targeting TAK1-binding protein 2
    • Xu C, Ren G, Cao G, et al. MiR-155 regulates immune modulatory properties of mesenchymal stem cells by targeting TAK1-binding protein 2. J Biol Chem. 2013;288:11074–11079.
    • (2013) J Biol Chem , vol.288 , pp. 11074-11079
    • Xu, C.1    Ren, G.2    Cao, G.3
  • 100
    • 84886055056 scopus 로고    scopus 로고
    • MiR-155 promotes proliferation of human breast cancer MCF-7 cells through targeting tumor protein 53-induced nuclear protein 1
    • Zhang C-M, Zhao J, Deng H-Y. MiR-155 promotes proliferation of human breast cancer MCF-7 cells through targeting tumor protein 53-induced nuclear protein 1. J Biomed Sci. 2013;20:79.
    • (2013) J Biomed Sci , vol.20 , pp. 79
    • Zhang, C.-M.1    Zhao, J.2    Deng, H.-Y.3
  • 101
    • 84880132922 scopus 로고    scopus 로고
    • MLH1 as a direct target of MiR-155 and a potential predictor of favorable prognosis in pancreatic cancer
    • Liu W-J, Zhao Y-P, Zhang T-P, et al. MLH1 as a direct target of MiR-155 and a potential predictor of favorable prognosis in pancreatic cancer. J Gastrointest Surg. 2013;17:1399–1405.
    • (2013) J Gastrointest Surg , vol.17 , pp. 1399-1405
    • Liu, W.-J.1    Zhao, Y.-P.2    Zhang, T.-P.3
  • 104
    • 77953308345 scopus 로고    scopus 로고
    • MicroRNA miR-155 inhibits bone morphogenetic protein (BMP) signaling and BMP-mediated Epstein-Barr virus reactivation
    • Yin Q, Wang X, Fewell C, et al. MicroRNA miR-155 inhibits bone morphogenetic protein (BMP) signaling and BMP-mediated Epstein-Barr virus reactivation. J Virol. 2010;84:6318–6327.
    • (2010) J Virol , vol.84 , pp. 6318-6327
    • Yin, Q.1    Wang, X.2    Fewell, C.3
  • 105
    • 84879413281 scopus 로고    scopus 로고
    • Mutant p53 drives invasion in breast tumors through up-regulation of miR-155
    • Neilsen PM, Noll JE, Mattiske S, et al. Mutant p53 drives invasion in breast tumors through up-regulation of miR-155. Oncogene. 2013;32:2992–3000.
    • (2013) Oncogene , vol.32 , pp. 2992-3000
    • Neilsen, P.M.1    Noll, J.E.2    Mattiske, S.3
  • 106
    • 84908046825 scopus 로고    scopus 로고
    • Evolution of the mir-155 family and possible targets in cancers and the immune system
    • Xie G-B, Liu W-J, Pan Z-J, Cheng T-Y, Luo C. Evolution of the mir-155 family and possible targets in cancers and the immune system. Asian Pac J Cancer Prev. 2014;15:7547–7552.
    • (2014) Asian Pac J Cancer Prev , vol.15 , pp. 7547-7552
    • Xie, G.-B.1    Liu, W.-J.2    Pan, Z.-J.3    Cheng, T.-Y.4    Luo, C.5
  • 107
    • 84878259075 scopus 로고    scopus 로고
    • The microRNA miR-155 controls CD8+ T cell responses by regulating interferon signaling
    • Gracias DT, Stelekati E, Hope JL, et al. The microRNA miR-155 controls CD8+ T cell responses by regulating interferon signaling. Nat Immunol. 2013;14:593–602.
    • (2013) Nat Immunol , vol.14 , pp. 593-602
    • Gracias, D.T.1    Stelekati, E.2    Hope, J.L.3
  • 108
    • 79953822796 scopus 로고    scopus 로고
    • MYB transcriptionally regulates the miR-155 host gene in chronic lymphocytic leukemia
    • Vargova K, Curik N, Burda P, et al. MYB transcriptionally regulates the miR-155 host gene in chronic lymphocytic leukemia. Blood. 2011;117:3816–3825.
    • (2011) Blood , vol.117 , pp. 3816-3825
    • Vargova, K.1    Curik, N.2    Burda, P.3
  • 109
    • 79956058235 scopus 로고    scopus 로고
    • MicroRNA-155 targets the SKI gene in human melanoma cell lines
    • Levati L, Pagani E, Romani S, et al. MicroRNA-155 targets the SKI gene in human melanoma cell lines. Pigment Cell Melanoma Res. 2011;24:538–550.
    • (2011) Pigment Cell Melanoma Res , vol.24 , pp. 538-550
    • Levati, L.1    Pagani, E.2    Romani, S.3
  • 110
    • 84920829033 scopus 로고    scopus 로고
    • Targeting miR-155 restores abnormal microglia and attenuates disease in SOD1 mice
    • Butovsky O, Jedrychowski MP, Cialic R, et al. Targeting miR-155 restores abnormal microglia and attenuates disease in SOD1 mice. Ann Neurol. 2015;77:75–99.
    • (2015) Ann Neurol , vol.77 , pp. 75-99
    • Butovsky, O.1    Jedrychowski, M.P.2    Cialic, R.3
  • 111
    • 84857981395 scopus 로고    scopus 로고
    • Aberrant expression of microRNA 155 may accelerate cell proliferation by targeting sex-determining region Y box 6 in hepatocellular carcinom
    • Xie Q, Chen X, Lu F, et al. Aberrant expression of microRNA 155 may accelerate cell proliferation by targeting sex-determining region Y box 6 in hepatocellular carcinom. Cancer. 2012;118:2431–2442.
    • (2012) Cancer , vol.118 , pp. 2431-2442
    • Xie, Q.1    Chen, X.2    Lu, F.3
  • 112
    • 79960741645 scopus 로고    scopus 로고
    • Quantitative proteomics identify novel miR-155 target proteins
    • Lößner C, Meier J, Warnken U, et al. Quantitative proteomics identify novel miR-155 target proteins. PLoS ONE. 2011;6:e22146.
    • (2011) PLoS ONE , vol.6
    • Lößner, C.1    Meier, J.2    Warnken, U.3
  • 113
    • 84900817879 scopus 로고    scopus 로고
    • MiRNA-155 targets myosin light chain kinase and modulates actin cytoskeleton organization in endothelial cells
    • Weber M, Kim S, Patterson N, Rooney K, Searles CD. MiRNA-155 targets myosin light chain kinase and modulates actin cytoskeleton organization in endothelial cells. Am J Physiol Heart Circ Physiol. 2014;306:H1192–H1203.
    • (2014) Am J Physiol Heart Circ Physiol , vol.306 , pp. H1192-H1203
    • Weber, M.1    Kim, S.2    Patterson, N.3    Rooney, K.4    Searles, C.D.5
  • 114
    • 84962324205 scopus 로고    scopus 로고
    • Inhibition of the miR-155 target NIAM phenocopies the growth promoting effect of miR-155 in B-cell lymphoma
    • Slezak-Prochazka I, Kluiver J, DE Jong D, et al. Inhibition of the miR-155 target NIAM phenocopies the growth promoting effect of miR-155 in B-cell lymphoma. Oncotarget. 2016;7:2391.
    • (2016) Oncotarget , vol.7 , pp. 2391
    • Slezak-Prochazka, I.1    Kluiver, J.2    DE Jong, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.