메뉴 건너뛰기




Volumn 359, Issue 2, 2015, Pages 288-298

TGF-β1 acts through miR-155 to down-regulate TP53INP1 in promoting epithelial-mesenchymal transition and cancer stem cell phenotypes

Author keywords

Cancer stem cell; Epithelial mesenchymal transition; MiR 155; TP53INP1; Tumour sphere

Indexed keywords

CD133 ANTIGEN; MICRORNA 155; NUCLEAR PROTEIN; OCTAMER TRANSCRIPTION FACTOR 4; PROTEIN TP53INP1; THY 1 ANTIGEN; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; CARRIER PROTEIN; HEAT SHOCK PROTEIN; MICRORNA; MIRN155 MICRORNA, HUMAN; TGFB1 PROTEIN, HUMAN; TP53INP1 PROTEIN, HUMAN;

EID: 84923078124     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2015.01.030     Document Type: Article
Times cited : (97)

References (52)
  • 2
    • 33751252276 scopus 로고    scopus 로고
    • Cancer metastasis: building a framework
    • Gupta G.P., Massague J. Cancer metastasis: building a framework. Cell 2006, 127:679-695.
    • (2006) Cell , vol.127 , pp. 679-695
    • Gupta, G.P.1    Massague, J.2
  • 3
    • 0038481970 scopus 로고    scopus 로고
    • The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited
    • Fidler I.J. The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited. Nat. Rev. Cancer 2003, 3:453-458.
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 453-458
    • Fidler, I.J.1
  • 4
    • 63049090100 scopus 로고    scopus 로고
    • Metastasis: from dissemination to organ-specific colonization
    • Nguyen D.X., Bos P.D., Massague J. Metastasis: from dissemination to organ-specific colonization. Nat. Rev. Cancer 2009, 9:274-284.
    • (2009) Nat. Rev. Cancer , vol.9 , pp. 274-284
    • Nguyen, D.X.1    Bos, P.D.2    Massague, J.3
  • 5
    • 63049123066 scopus 로고    scopus 로고
    • Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits
    • Polyak K., Weinberg R.A. Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits. Nat. Rev. Cancer 2009, 9:265-273.
    • (2009) Nat. Rev. Cancer , vol.9 , pp. 265-273
    • Polyak, K.1    Weinberg, R.A.2
  • 6
    • 84907516355 scopus 로고    scopus 로고
    • PRMT7 induces epithelial-to-mesenchymal transition and promotes metastasis in breast cancer
    • Yao R., Jiang H., Ma Y., Wang L., Wang L., Du J., et al. PRMT7 induces epithelial-to-mesenchymal transition and promotes metastasis in breast cancer. Cancer Res 2014, 74:5656-5667.
    • (2014) Cancer Res , vol.74 , pp. 5656-5667
    • Yao, R.1    Jiang, H.2    Ma, Y.3    Wang, L.4    Wang, L.5    Du, J.6
  • 7
    • 84900511675 scopus 로고    scopus 로고
    • Activated androgen receptor promotes bladder cancer metastasis via Slug mediated epithelial-mesenchymal transition
    • Jing Y., Cui D., Guo W., Jiang J., Jiang B., Lu Y., et al. Activated androgen receptor promotes bladder cancer metastasis via Slug mediated epithelial-mesenchymal transition. Cancer Lett 2014, 348:135-145.
    • (2014) Cancer Lett , vol.348 , pp. 135-145
    • Jing, Y.1    Cui, D.2    Guo, W.3    Jiang, J.4    Jiang, B.5    Lu, Y.6
  • 8
    • 84892881387 scopus 로고    scopus 로고
    • CD133 facilitates epithelial-mesenchymal transition through interaction with the ERK pathway in pancreatic cancer metastasis
    • Ding Q., Miyazaki Y., Tsukasa K., Matsubara S., Yoshimitsu M., Takao S. CD133 facilitates epithelial-mesenchymal transition through interaction with the ERK pathway in pancreatic cancer metastasis. Mol. Cancer 2014, 13:15.
    • (2014) Mol. Cancer , vol.13 , pp. 15
    • Ding, Q.1    Miyazaki, Y.2    Tsukasa, K.3    Matsubara, S.4    Yoshimitsu, M.5    Takao, S.6
  • 9
    • 84866338445 scopus 로고    scopus 로고
    • TGF-beta in epithelial to mesenchymal transition and metastasis of liver carcinoma
    • Reichl P., Haider C., Grubinger M., Mikulits W. TGF-beta in epithelial to mesenchymal transition and metastasis of liver carcinoma. Curr. Pharm. Des 2012, 18:4135-4147.
    • (2012) Curr. Pharm. Des , vol.18 , pp. 4135-4147
    • Reichl, P.1    Haider, C.2    Grubinger, M.3    Mikulits, W.4
  • 10
    • 70450198396 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in development and disease
    • Thiery J.P., Acloque H., Huang R.Y., Nieto M.A. Epithelial-mesenchymal transitions in development and disease. Cell 2009, 139:871-890.
    • (2009) Cell , vol.139 , pp. 871-890
    • Thiery, J.P.1    Acloque, H.2    Huang, R.Y.3    Nieto, M.A.4
  • 11
    • 42749091317 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition and the invasive potential of tumors
    • Gavert N., Ben-Ze'ev A. Epithelial-mesenchymal transition and the invasive potential of tumors. Trends Mol. Med 2008, 14:199-209.
    • (2008) Trends Mol. Med , vol.14 , pp. 199-209
    • Gavert, N.1    Ben-Ze'ev, A.2
  • 14
    • 52549087785 scopus 로고    scopus 로고
    • Cancer stem cells in solid tumours: accumulating evidence and unresolved questions
    • Visvader J.E., Lindeman G.J. Cancer stem cells in solid tumours: accumulating evidence and unresolved questions. Nat. Rev. Cancer 2008, 8:755-768.
    • (2008) Nat. Rev. Cancer , vol.8 , pp. 755-768
    • Visvader, J.E.1    Lindeman, G.J.2
  • 15
    • 38549139140 scopus 로고    scopus 로고
    • Significance of CD90+ cancer stem cells in human liver cancer
    • Yang Z.F., Ho D.W., Ng M.N., Lau C.K., Yu W.C., Ngai P., et al. Significance of CD90+ cancer stem cells in human liver cancer. Cancer Cell 2008, 13:153-166.
    • (2008) Cancer Cell , vol.13 , pp. 153-166
    • Yang, Z.F.1    Ho, D.W.2    Ng, M.N.3    Lau, C.K.4    Yu, W.C.5    Ngai, P.6
  • 16
    • 78649681554 scopus 로고    scopus 로고
    • MiR-130b promotes CD133(+) liver tumor-initiating cell growth and self-renewal via tumor protein 53-induced nuclear protein 1
    • Ma S., Tang K.H., Chan Y.P., Lee T.K., Kwan P.S., Castilho A., et al. MiR-130b promotes CD133(+) liver tumor-initiating cell growth and self-renewal via tumor protein 53-induced nuclear protein 1. Cell Stem Cell 2010, 7:694-707.
    • (2010) Cell Stem Cell , vol.7 , pp. 694-707
    • Ma, S.1    Tang, K.H.2    Chan, Y.P.3    Lee, T.K.4    Kwan, P.S.5    Castilho, A.6
  • 17
    • 84876098953 scopus 로고    scopus 로고
    • Discrete nature of EpCAM+ and CD90+ cancer stem cells in human hepatocellular carcinoma
    • Yamashita T., Honda M., Nakamoto Y., Baba M., Nio K., Hara Y., et al. Discrete nature of EpCAM+ and CD90+ cancer stem cells in human hepatocellular carcinoma. Hepatology 2013, 57:1484-1497.
    • (2013) Hepatology , vol.57 , pp. 1484-1497
    • Yamashita, T.1    Honda, M.2    Nakamoto, Y.3    Baba, M.4    Nio, K.5    Hara, Y.6
  • 18
    • 65649095142 scopus 로고    scopus 로고
    • Side population of pancreatic cancer cells predominates in TGF-beta-mediated epithelial to mesenchymal transition and invasion
    • Kabashima A., Higuchi H., Takaishi H., Matsuzaki Y., Suzuki S., Izumiya M., et al. Side population of pancreatic cancer cells predominates in TGF-beta-mediated epithelial to mesenchymal transition and invasion. Int. J. Cancer 2009, 124:2771-2779.
    • (2009) Int. J. Cancer , vol.124 , pp. 2771-2779
    • Kabashima, A.1    Higuchi, H.2    Takaishi, H.3    Matsuzaki, Y.4    Suzuki, S.5    Izumiya, M.6
  • 19
    • 79958271033 scopus 로고    scopus 로고
    • Sphere-forming cell subpopulations with cancer stem cell properties in human hepatoma cell lines
    • Cao L., Zhou Y., Zhai B., Liao J., Xu W., Zhang R., et al. Sphere-forming cell subpopulations with cancer stem cell properties in human hepatoma cell lines. BMC Gastroenterol 2011, 11:71.
    • (2011) BMC Gastroenterol , vol.11 , pp. 71
    • Cao, L.1    Zhou, Y.2    Zhai, B.3    Liao, J.4    Xu, W.5    Zhang, R.6
  • 20
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: genomics, biogenesis, mechanism, and function
    • Bartel D.P. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004, 116:281-297.
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 21
    • 27244432205 scopus 로고    scopus 로고
    • MicroRNAs as oncogenes and tumor suppressors
    • Chen C.Z. MicroRNAs as oncogenes and tumor suppressors. N. Engl. J. Med 2005, 353:1768-1771.
    • (2005) N. Engl. J. Med , vol.353 , pp. 1768-1771
    • Chen, C.Z.1
  • 23
    • 84892671815 scopus 로고    scopus 로고
    • MicroRNAs regulate both epithelial-to-mesenchymal transition and cancer stem cells
    • Ceppi P., Peter M.E. MicroRNAs regulate both epithelial-to-mesenchymal transition and cancer stem cells. Oncogene 2014, 33:269-278.
    • (2014) Oncogene , vol.33 , pp. 269-278
    • Ceppi, P.1    Peter, M.E.2
  • 24
    • 68949170622 scopus 로고    scopus 로고
    • Identification of microRNA-181 by genome-wide screening as a critical player in EpCAM-positive hepatic cancer stem cells
    • Ji J., Yamashita T., Budhu A., Forgues M., Jia H.L., Li C., et al. Identification of microRNA-181 by genome-wide screening as a critical player in EpCAM-positive hepatic cancer stem cells. Hepatology 2009, 50:472-480.
    • (2009) Hepatology , vol.50 , pp. 472-480
    • Ji, J.1    Yamashita, T.2    Budhu, A.3    Forgues, M.4    Jia, H.L.5    Li, C.6
  • 25
    • 55849123946 scopus 로고    scopus 로고
    • MicroRNA-155 is regulated by the transforming growth factor beta/Smad pathway and contributes to epithelial cell plasticity by targeting RhoA
    • Kong W., Yang H., He L., Zhao J.J., Coppola D., Dalton W.S., et al. MicroRNA-155 is regulated by the transforming growth factor beta/Smad pathway and contributes to epithelial cell plasticity by targeting RhoA. Mol. Cell. Biol 2008, 28:6773-6784.
    • (2008) Mol. Cell. Biol , vol.28 , pp. 6773-6784
    • Kong, W.1    Yang, H.2    He, L.3    Zhao, J.J.4    Coppola, D.5    Dalton, W.S.6
  • 26
    • 84876465381 scopus 로고    scopus 로고
    • MicroRNA-155 is a novel suppressor of ovarian cancer-initiating cells that targets CLDN1
    • Qin W., Ren Q., Liu T., Huang Y., Wang J. MicroRNA-155 is a novel suppressor of ovarian cancer-initiating cells that targets CLDN1. FEBS Lett 2013, 587:1434-1439.
    • (2013) FEBS Lett , vol.587 , pp. 1434-1439
    • Qin, W.1    Ren, Q.2    Liu, T.3    Huang, Y.4    Wang, J.5
  • 27
    • 0032742269 scopus 로고    scopus 로고
    • New human hepatocellular carcinoma (HCC) cell line with highly metastatic potential (MHCC97) and its expressions of the factors associated with metastasis
    • Tian J., Tang Z.Y., Ye S.L., Liu Y.K., Lin Z.Y., Chen J., et al. New human hepatocellular carcinoma (HCC) cell line with highly metastatic potential (MHCC97) and its expressions of the factors associated with metastasis. Br. J. Cancer 1999, 81:814-821.
    • (1999) Br. J. Cancer , vol.81 , pp. 814-821
    • Tian, J.1    Tang, Z.Y.2    Ye, S.L.3    Liu, Y.K.4    Lin, Z.Y.5    Chen, J.6
  • 28
    • 0037250193 scopus 로고    scopus 로고
    • Establishment of a hepatocellular carcinoma cell line with unique metastatic characteristics through in vivo selection and screening for metastasis-related genes through cDNA microarray
    • Li Y., Tang Y., Ye L., Liu B., Liu K., Chen J., et al. Establishment of a hepatocellular carcinoma cell line with unique metastatic characteristics through in vivo selection and screening for metastasis-related genes through cDNA microarray. J. Cancer Res. Clin. Oncol 2003, 129:43-51.
    • (2003) J. Cancer Res. Clin. Oncol , vol.129 , pp. 43-51
    • Li, Y.1    Tang, Y.2    Ye, L.3    Liu, B.4    Liu, K.5    Chen, J.6
  • 29
    • 84874782801 scopus 로고    scopus 로고
    • MicroRNA-320 suppresses the stem cell-like characteristics of prostate cancer cells by downregulating the Wnt/beta-catenin signaling pathway
    • Hsieh I.S., Chang K.C., Tsai Y.T., Ke J.Y., Lu P.J., Lee K.H., et al. MicroRNA-320 suppresses the stem cell-like characteristics of prostate cancer cells by downregulating the Wnt/beta-catenin signaling pathway. Carcinogenesis 2013, 34:530-538.
    • (2013) Carcinogenesis , vol.34 , pp. 530-538
    • Hsieh, I.S.1    Chang, K.C.2    Tsai, Y.T.3    Ke, J.Y.4    Lu, P.J.5    Lee, K.H.6
  • 30
    • 84858992906 scopus 로고    scopus 로고
    • Loss of brain-enriched miR-124 microRNA enhances stem-like traits and invasiveness of glioma cells
    • Xia H., Cheung W.K., Ng S.S., Jiang X., Jiang S., Sze J., et al. Loss of brain-enriched miR-124 microRNA enhances stem-like traits and invasiveness of glioma cells. J. Biol. Chem 2012, 287:9962-9971.
    • (2012) J. Biol. Chem , vol.287 , pp. 9962-9971
    • Xia, H.1    Cheung, W.K.2    Ng, S.S.3    Jiang, X.4    Jiang, S.5    Sze, J.6
  • 31
    • 0037948854 scopus 로고    scopus 로고
    • In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells
    • Dontu G., Abdallah W.M., Foley J.M., Jackson K.W., Clarke M.F., Kawamura M.J., et al. In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells. Genes Dev 2003, 17:1253-1270.
    • (2003) Genes Dev , vol.17 , pp. 1253-1270
    • Dontu, G.1    Abdallah, W.M.2    Foley, J.M.3    Jackson, K.W.4    Clarke, M.F.5    Kawamura, M.J.6
  • 32
    • 84885083594 scopus 로고    scopus 로고
    • MicroRNA-218 inhibits glioma invasion, migration, proliferation, and cancer stem-like cell self-renewal by targeting the polycomb group gene Bmi1
    • Tu Y., Gao X., Li G., Fu H., Cui D., Liu H., et al. MicroRNA-218 inhibits glioma invasion, migration, proliferation, and cancer stem-like cell self-renewal by targeting the polycomb group gene Bmi1. Cancer Res 2013, 73:6046-6055.
    • (2013) Cancer Res , vol.73 , pp. 6046-6055
    • Tu, Y.1    Gao, X.2    Li, G.3    Fu, H.4    Cui, D.5    Liu, H.6
  • 33
    • 84875916963 scopus 로고    scopus 로고
    • Positive correlation of Oct4 and ABCG2 to chemotherapeutic resistance in CD90(+)CD133(+) liver cancer stem cells
    • Jia Q., Zhang X., Deng T., Gao J. Positive correlation of Oct4 and ABCG2 to chemotherapeutic resistance in CD90(+)CD133(+) liver cancer stem cells. Cell Reprogram 2013, 15:143-150.
    • (2013) Cell Reprogram , vol.15 , pp. 143-150
    • Jia, Q.1    Zhang, X.2    Deng, T.3    Gao, J.4
  • 34
    • 84899483530 scopus 로고    scopus 로고
    • MiR-612 suppresses the stemness of liver cancer via Wnt/beta-catenin signalling
    • Tang J., Tao Z.H., Wen D., Wan J.L., Liu D.L., Zhang S., et al. MiR-612 suppresses the stemness of liver cancer via Wnt/beta-catenin signalling. Biochem. Biophys. Res. Commun 2014, 447:210-215.
    • (2014) Biochem. Biophys. Res. Commun , vol.447 , pp. 210-215
    • Tang, J.1    Tao, Z.H.2    Wen, D.3    Wan, J.L.4    Liu, D.L.5    Zhang, S.6
  • 35
    • 34547197024 scopus 로고    scopus 로고
    • Spheres isolated from 9L gliosarcoma rat cell line possess chemoresistant and aggressive cancer stem-like cells
    • Ghods A.J., Irvin D., Liu G., Yuan X., Abdulkadir I.R., Tunici P., et al. Spheres isolated from 9L gliosarcoma rat cell line possess chemoresistant and aggressive cancer stem-like cells. Stem Cells 2007, 25:1645-1653.
    • (2007) Stem Cells , vol.25 , pp. 1645-1653
    • Ghods, A.J.1    Irvin, D.2    Liu, G.3    Yuan, X.4    Abdulkadir, I.R.5    Tunici, P.6
  • 36
    • 43049165453 scopus 로고    scopus 로고
    • The epithelial-mesenchymal transition generates cells with properties of stem cells
    • Mani S.A., Guo W., Liao M.J., Eaton E.N., Ayyanan A., Zhou A.Y., et al. The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 2008, 133:704-715.
    • (2008) Cell , vol.133 , pp. 704-715
    • Mani, S.A.1    Guo, W.2    Liao, M.J.3    Eaton, E.N.4    Ayyanan, A.5    Zhou, A.Y.6
  • 37
    • 79961168650 scopus 로고    scopus 로고
    • MiR-155 promotes macroscopic tumor formation yet inhibits tumor dissemination from mammary fat pads to the lung by preventing EMT
    • Xiang X., Zhuang X., Ju S., Zhang S., Jiang H., Mu J., et al. miR-155 promotes macroscopic tumor formation yet inhibits tumor dissemination from mammary fat pads to the lung by preventing EMT. Oncogene 2011, 30:3440-3453.
    • (2011) Oncogene , vol.30 , pp. 3440-3453
    • Xiang, X.1    Zhuang, X.2    Ju, S.3    Zhang, S.4    Jiang, H.5    Mu, J.6
  • 38
    • 36048952786 scopus 로고    scopus 로고
    • Tumor protein 53-induced nuclear protein 1 expression is repressed by miR-155, and its restoration inhibits pancreatic tumor development
    • Gironella M., Seux M., Xie M.J., Cano C., Tomasini R., Gommeaux J., et al. Tumor protein 53-induced nuclear protein 1 expression is repressed by miR-155, and its restoration inhibits pancreatic tumor development. Proc. Natl. Acad. Sci. U.S.A. 2007, 104:16170-16175.
    • (2007) Proc. Natl. Acad. Sci. U.S.A. , vol.104 , pp. 16170-16175
    • Gironella, M.1    Seux, M.2    Xie, M.J.3    Cano, C.4    Tomasini, R.5    Gommeaux, J.6
  • 39
    • 84878467113 scopus 로고    scopus 로고
    • 17beta-estradiol up-regulates miR-155 expression and reduces TP53INP1 expression in MCF-7 breast cancer cells
    • Zhang C., Zhao J., Deng H. 17beta-estradiol up-regulates miR-155 expression and reduces TP53INP1 expression in MCF-7 breast cancer cells. Mol. Cell. Biochem 2013, 379:201-211.
    • (2013) Mol. Cell. Biochem , vol.379 , pp. 201-211
    • Zhang, C.1    Zhao, J.2    Deng, H.3
  • 40
    • 84860230610 scopus 로고    scopus 로고
    • Dynamic equilibrium between cancer stem cells and non-stem cancer cells in human SW620 and MCF-7 cancer cell populations
    • Yang G., Quan Y., Wang W., Fu Q., Wu J., Mei T., et al. Dynamic equilibrium between cancer stem cells and non-stem cancer cells in human SW620 and MCF-7 cancer cell populations. Br. J. Cancer 2012, 106:1512-1519.
    • (2012) Br. J. Cancer , vol.106 , pp. 1512-1519
    • Yang, G.1    Quan, Y.2    Wang, W.3    Fu, Q.4    Wu, J.5    Mei, T.6
  • 41
    • 84907977435 scopus 로고    scopus 로고
    • Transforming growth factor-beta1-induced epithelial-mesenchymal transition generates ALDH-positive cells with stem cell properties in cholangiocarcinoma
    • Shuang Z.Y., Wu W.C., Xu J., Lin G., Liu Y.C., Lao X.M., et al. Transforming growth factor-beta1-induced epithelial-mesenchymal transition generates ALDH-positive cells with stem cell properties in cholangiocarcinoma. Cancer Lett 2014, 354:320-328.
    • (2014) Cancer Lett , vol.354 , pp. 320-328
    • Shuang, Z.Y.1    Wu, W.C.2    Xu, J.3    Lin, G.4    Liu, Y.C.5    Lao, X.M.6
  • 42
    • 47549090432 scopus 로고    scopus 로고
    • TGFbeta in cancer
    • Massague J. TGFbeta in cancer. Cell 2008, 134:215-230.
    • (2008) Cell , vol.134 , pp. 215-230
    • Massague, J.1
  • 43
  • 44
    • 84873250716 scopus 로고    scopus 로고
    • Up-regulated microRNA-143 in cancer stem cells differentiation promotes prostate cancer cells metastasis by modulating FNDC3B expression
    • Fan X., Chen X., Deng W., Zhong G., Cai Q., Lin T. Up-regulated microRNA-143 in cancer stem cells differentiation promotes prostate cancer cells metastasis by modulating FNDC3B expression. BMC Cancer 2013, 13:61.
    • (2013) BMC Cancer , vol.13 , pp. 61
    • Fan, X.1    Chen, X.2    Deng, W.3    Zhong, G.4    Cai, Q.5    Lin, T.6
  • 45
    • 84861686487 scopus 로고    scopus 로고
    • MiR-21 regulates epithelial-mesenchymal transition phenotype and hypoxia-inducible factor-1alpha expression in third-sphere forming breast cancer stem cell-like cells
    • Han M., Wang Y., Liu M., Bi X., Bao J., Zeng N., et al. MiR-21 regulates epithelial-mesenchymal transition phenotype and hypoxia-inducible factor-1alpha expression in third-sphere forming breast cancer stem cell-like cells. Cancer Sci 2012, 103:1058-1064.
    • (2012) Cancer Sci , vol.103 , pp. 1058-1064
    • Han, M.1    Wang, Y.2    Liu, M.3    Bi, X.4    Bao, J.5    Zeng, N.6
  • 46
    • 84890572219 scopus 로고    scopus 로고
    • MiR-155-mediated loss of C/EBPbeta shifts the TGF-beta response from growth inhibition to epithelial-mesenchymal transition, invasion and metastasis in breast cancer
    • Johansson J., Berg T., Kurzejamska E., Pang M.F., Tabor V., Jansson M., et al. MiR-155-mediated loss of C/EBPbeta shifts the TGF-beta response from growth inhibition to epithelial-mesenchymal transition, invasion and metastasis in breast cancer. Oncogene 2013, 32:5614-5624.
    • (2013) Oncogene , vol.32 , pp. 5614-5624
    • Johansson, J.1    Berg, T.2    Kurzejamska, E.3    Pang, M.F.4    Tabor, V.5    Jansson, M.6
  • 47
    • 79960047108 scopus 로고    scopus 로고
    • TP53INP1 decreases pancreatic cancer cell migration by regulating SPARC expression
    • Seux M., Peuget S., Montero M.P., Siret C., Rigot V., Clerc P., et al. TP53INP1 decreases pancreatic cancer cell migration by regulating SPARC expression. Oncogene 2011, 30:3049-3061.
    • (2011) Oncogene , vol.30 , pp. 3049-3061
    • Seux, M.1    Peuget, S.2    Montero, M.P.3    Siret, C.4    Rigot, V.5    Clerc, P.6
  • 48
    • 63749105896 scopus 로고    scopus 로고
    • Mechanism of TGF-beta signaling to growth arrest, apoptosis, and epithelial-mesenchymal transition
    • Heldin C.H., Landstrom M., Moustakas A. Mechanism of TGF-beta signaling to growth arrest, apoptosis, and epithelial-mesenchymal transition. Curr. Opin. Cell Biol 2009, 21:166-176.
    • (2009) Curr. Opin. Cell Biol , vol.21 , pp. 166-176
    • Heldin, C.H.1    Landstrom, M.2    Moustakas, A.3
  • 49
    • 84874782064 scopus 로고    scopus 로고
    • Downregulation of miR-153 contributes to epithelial-mesenchymal transition and tumor metastasis in human epithelial cancer
    • Xu Q., Sun Q., Zhang J., Yu J., Chen W., Zhang Z. Downregulation of miR-153 contributes to epithelial-mesenchymal transition and tumor metastasis in human epithelial cancer. Carcinogenesis 2013, 34:539-549.
    • (2013) Carcinogenesis , vol.34 , pp. 539-549
    • Xu, Q.1    Sun, Q.2    Zhang, J.3    Yu, J.4    Chen, W.5    Zhang, Z.6
  • 50
    • 77953467576 scopus 로고    scopus 로고
    • Spred2 inhibits TGF-beta1-induced urokinase type plasminogen activator expression, cell motility and epithelial mesenchymal transition
    • Villar V., Kocic J., Santibanez J.F. Spred2 inhibits TGF-beta1-induced urokinase type plasminogen activator expression, cell motility and epithelial mesenchymal transition. Int. J. Cancer 2010, 127:77-85.
    • (2010) Int. J. Cancer , vol.127 , pp. 77-85
    • Villar, V.1    Kocic, J.2    Santibanez, J.F.3
  • 51
    • 79959735149 scopus 로고    scopus 로고
    • Epithelial to mesenchymal transition by TGFbeta-1 induction increases stemness characteristics in primary non small cell lung cancer cell line
    • Pirozzi G., Tirino V., Camerlingo R., Franco R., La Rocca A., Liguori E., et al. Epithelial to mesenchymal transition by TGFbeta-1 induction increases stemness characteristics in primary non small cell lung cancer cell line. PLoS ONE 2011, 6:e21548.
    • (2011) PLoS ONE , vol.6 , pp. e21548
    • Pirozzi, G.1    Tirino, V.2    Camerlingo, R.3    Franco, R.4    La Rocca, A.5    Liguori, E.6
  • 52
    • 84906053870 scopus 로고    scopus 로고
    • Tumor-associated macrophages promote cancer stem cell-like properties via transforming growth factor-beta1-induced epithelial-mesenchymal transition in hepatocellular carcinoma
    • Fan Q.M., Jing Y.Y., Yu G.F., Kou X.R., Ye F., Gao L., et al. Tumor-associated macrophages promote cancer stem cell-like properties via transforming growth factor-beta1-induced epithelial-mesenchymal transition in hepatocellular carcinoma. Cancer Lett 2014, 352:160-168.
    • (2014) Cancer Lett , vol.352 , pp. 160-168
    • Fan, Q.M.1    Jing, Y.Y.2    Yu, G.F.3    Kou, X.R.4    Ye, F.5    Gao, L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.