Deregulated miR-155 promotes Fas-mediated apoptosis in human intervertebral disc degeneration by targeting FADD and caspase-3

Journal of Pathology

Volumn 225, Issue 2, 2011, Pages 232-242

  Wang, Hai Qiang ^a   Yu, Xiao Dong ^a   Liu, Zhi Heng ^a   Cheng, Xin ^b   Samartzis, Dino ^c   Jia, Lin Tao ^b   Wu, Sheng Xi ^b   Huang, Jing ^b   Chen, Jing ^b   Luo, Zhuo Jing ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^c UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

apoptosis; caspase 3; disc degeneration; FADD; miR 155; miRNAs; nucleus pulposus

Indexed keywords

CASPASE 3; FAS ANTIGEN; FAS ASSOCIATED DEATH DOMAIN PROTEIN; LENTIVIRUS VECTOR; MICRORNA; MICRORNA 155; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; ADULT; APOPTOSIS; ARTICLE; BINDING SITE; BIOINFORMATICS; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOPLASM; DOWN REGULATION; FLOW CYTOMETRY; GENE MUTATION; GENE OVEREXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN TISSUE; INTERVERTEBRAL DISK DEGENERATION; NUCLEOTIDE SEQUENCE; NUCLEUS PULPOSUS; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING;

ADULT; ANTIGENS, CD95; APOPTOSIS; BLOTTING, WESTERN; CASPASE 3; CELL SEPARATION; FAS-ASSOCIATED DEATH DOMAIN PROTEIN; FLOW CYTOMETRY; GENE EXPRESSION; GENE EXPRESSION REGULATION; HUMANS; IMMUNOHISTOCHEMISTRY; INTERVERTEBRAL DISK DEGENERATION; MICRORNAS; MICROSCOPY, ELECTRON, TRANSMISSION; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 80052460614     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.2931     Document Type: Article

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