MicroRNA-23a antisense enhances 5-fluorouracil chemosensitivity through apaf-1/caspase-9 apoptotic pathway in colorectal cancer cells

Journal of Cellular Biochemistry

Volumn 115, Issue 4, 2014, Pages 772-784

  Shang, Jingli ^a   Yang, Fu ^a   Wang, Yuzhao ^a   Wang, Yue ^a   Xue, Geng ^a   Mei, Qian ^a   Wang, Fang ^a   Sun, Shuhan ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

5 FLUOROURACIL (5 FU); APOPTOSIS; Apoptosis Activating Factor 1(APAF 1); COLORECTAL CANCER (CRC); microRNA 23a (miR 23a)

Indexed keywords

APOPTOTIC PROTEASE ACTIVATING FACTOR 1; CASPASE 3; CASPASE 7; CASPASE 9; FLUOROURACIL; MICRORNA; MICRORNA 23A; UNCLASSIFIED DRUG;

ADULT; AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER CHEMOTHERAPY; CELL PROLIFERATION; CELL VIABILITY; CHEMOSENSITIVITY; COLORECTAL CANCER; CONTROLLED STUDY; CYTOTOXICITY; DOWN REGULATION; ENZYME ACTIVATION; FEMALE; HUMAN; HUMAN CELL; IC 50; IN VIVO STUDY; MAJOR CLINICAL STUDY; MALE; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TREATMENT DURATION; TUMOR XENOGRAFT; UPREGULATION;

5-FLUOROURACIL (5-FU); APOPTOSIS; APOPTOSIS-ACTIVATING FACTOR-1(APAF-1); COLORECTAL CANCER (CRC); MICRORNA-23A (MIR-23A);

AGED; ANIMALS; ANTIMETABOLITES, ANTINEOPLASTIC; APOPTOSIS; APOPTOTIC PROTEASE-ACTIVATING FACTOR 1; BASE SEQUENCE; CASPASE 9; COLONIC NEOPLASMS; COLORECTAL NEOPLASMS; FEMALE; FLUOROURACIL; GENE EXPRESSION REGULATION, NEOPLASTIC; HCT116 CELLS; HT29 CELLS; HUMANS; MALE; MICE; MICRORNAS; MIDDLE AGED; MOLECULAR SEQUENCE DATA; OLIGONUCLEOTIDES, ANTISENSE; SIGNAL TRANSDUCTION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84892919523     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.24721     Document Type: Article

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