p53DINP1, a p53-inducible gene, regulates p53-dependent apoptosis

Molecular Cell

Volumn 8, Issue 1, 2001, Pages 85-94

  Okamura, Shu ^a,b   Arakawa, Hirofumi ^a   Tanaka, Tomoaki ^c   Nakanishi, Hiroshi ^a   Ng, Ching Ching ^a   Taya, Yoichi ^c   Monden, Morito ^b   Nakamura, Yusuke ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; DOUBLE STRANDED DNA; PROTEIN P53; PROTEIN SERINE KINASE;

APOPTOSIS; ARTICLE; CELL DEATH; CELL LINE; CELL STRAIN MCF 7; CONTROLLED STUDY; DNA DAMAGE; DNA STRAND BREAKAGE; GENE; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE INDUCTION; GENE ISOLATION; GENE OVEREXPRESSION; GENOTOXICITY; HUMAN; HUMAN CELL; PROTEIN DNA INTERACTION; PROTEIN PHOSPHORYLATION;

MINK CELL FOCUS-FORMING VIRUS;

EID: 0034891004     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(01)00284-2     Document Type: Article

References (31)

1. Phosphorylation of human p53 by p38 kinase coordinates N-terminal phosphorylation and apoptosis in response to UV radiation
2. High expression of the DNA methyltransferase gene characterizes human neoplastic cells and progression stages of colon cancer
3. Definition of a consensus binding site for p53
4. WAF1, a potential mediator of p53 tumor suppression
5. Isolation of a novel GPI-anchored gene specifically regulated by p53; correlation between its expression and anti-cancer drug sensitivity
6. The complexity of p53 modulation: Emerging patterns from divergent signals
7. Mutations in the p53 tumor suppressor gene: Clues to cancer etiology and molecular pathogenesis
8. Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain
9. CSR, a scavenger receptor-like protein with a protective role against cellular damage caused by UV irradiation and oxidative stress
10. The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases
11. DNA damage-induced activation of p53 by the checkpoint kinase Chk2
12. Identification of genes involved in repair of DNA double-strand breaks in mammalian cells
13. Genomic structure and chromosomal localization of GML (GPI-anchored molecule-like protein), a gene induced by p53
14. p53, the celluar gatekeeper for growth and division
15. Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
16. The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation
17. Isolation and characterization of a novel TP53-inducible gene, TP53TG3
18. A novel brain-specific p53-target gene, BAI1, containing thrombospondin type 1 repeats inhibits experimental angiogenesis
19. p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53
20. Identification of seven genes regulated by wild-type p53 in a colon cancer cell line carrying a well-controlled wild-type p53 expression system
21. Amplification of a gene encoding a p53-associated protein in human sarcomas
22. Kinetics of p56lck and p60src Src homology 2 domain binding to tyrosine-phosphorylated peptides determined by a competition assay or surface plasmon resonance
23. Signaling to p53: Breaking the MDM2-p53 circuit
24. Inhibition of ATM and ATR kinase activities by the radiosensitizing agent, caffeine
25. DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2
26. DNA damage-inducible phosphorylation of p53 at N-terminal sites including a novel site, Ser20, requires tetramerization
27. Homologous recombination and non-homologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells
28. Isolation of a novel TP53 target gene from a colon cancer cell line carrying a highly regulated wild-type TP53 expression system
29. A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint for DNA damage
30. Cloning of P2XM, a novel human P2X receptor gene regulated by p53
31. Analysis of inducers of the E. coli lac repressor system in mammalian cells and whole animals