-
1
-
-
79952284127
-
Hallmarks of cancer: the next generation
-
Hanahan D, Weinberg RA (2011) Hallmarks of cancer: the next generation. Cell 144, 646-674.
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
2
-
-
0034641918
-
The biochemistry of apoptosis
-
Hengartner MO (2000) The biochemistry of apoptosis. Nature 407, 770-776.
-
(2000)
Nature
, vol.407
, pp. 770-776
-
-
Hengartner, M.O.1
-
3
-
-
69449095860
-
Caspases and kinases in a death grip
-
Kurokawa M, Kornbluth S (2009) Caspases and kinases in a death grip. Cell 138, 838-854.
-
(2009)
Cell
, vol.138
, pp. 838-854
-
-
Kurokawa, M.1
Kornbluth, S.2
-
4
-
-
0027525104
-
The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme
-
Yuan J, Shaham S, Ledoux S, Ellis HM, Horvitz HR (1993) The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme. Cell 75, 641-652.
-
(1993)
Cell
, vol.75
, pp. 641-652
-
-
Yuan, J.1
Shaham, S.2
Ledoux, S.3
Ellis, H.M.4
Horvitz, H.R.5
-
7
-
-
54249096028
-
Caspases in apoptosis and beyond
-
Li J, Yuan J (2008) Caspases in apoptosis and beyond. Oncogene 27, 6194-6206.
-
(2008)
Oncogene
, vol.27
, pp. 6194-6206
-
-
Li, J.1
Yuan, J.2
-
8
-
-
57749089665
-
Caspase-mediated cleavage of ATG6/Beclin-1 links apoptosis in HeLa cells
-
Cho DH, Jo YK, Hwang JJ, Lee YM, Roh SA, Kim JC (2009) Caspase-mediated cleavage of ATG6/Beclin-1 links apoptosis in HeLa cells. Cancer Lett. 274, 95-100.
-
(2009)
Cancer Lett.
, vol.274
, pp. 95-100
-
-
Cho, D.H.1
Jo, Y.K.2
Hwang, J.J.3
Lee, Y.M.4
Roh, S.A.5
Kim, J.C.6
-
9
-
-
78650746461
-
Involvement of caspase-9 in autophagy-mediated cell survival pathway
-
Jeong HS, Choi HY, Lee ER, Kim JH, Jeon K, Lee HJ et al. (2010) Involvement of caspase-9 in autophagy-mediated cell survival pathway. Biochim. Biophys. Acta 1813, 80-90.
-
(2010)
Biochim. Biophys. Acta
, vol.1813
, pp. 80-90
-
-
Jeong, H.S.1
Choi, H.Y.2
Lee, E.R.3
Kim, J.H.4
Jeon, K.5
Lee, H.J.6
-
10
-
-
80054087824
-
Mitochondrial ROS generation for regulation of autophagic pathways in cancer
-
Li ZY, Yang Y, Ming M, Liu B (2011) Mitochondrial ROS generation for regulation of autophagic pathways in cancer. Biochem. Biophys. Res. Commun. 414, 5-8.
-
(2011)
Biochem. Biophys. Res. Commun.
, vol.414
, pp. 5-8
-
-
Li, Z.Y.1
Yang, Y.2
Ming, M.3
Liu, B.4
-
11
-
-
16644394363
-
Caspases: potential targets for regulating cell death
-
Philchenkov A (2004) Caspases: potential targets for regulating cell death. J. Cell Mol. Med. 8, 432-444.
-
(2004)
J. Cell Mol. Med.
, vol.8
, pp. 432-444
-
-
Philchenkov, A.1
-
12
-
-
0033667778
-
FADD/MORT1 and caspase-8 are recruited to TRAIL Receptors 1 and 2 and are essential for apoptosis mediated by TRAIL Receptor 2
-
Sprick MR, Weigand MA, Rieser E, Rauch CT, Juo P, Blenis J et al. (2000) FADD/MORT1 and caspase-8 are recruited to TRAIL Receptors 1 and 2 and are essential for apoptosis mediated by TRAIL Receptor 2. Immunity, 12, 599-609.
-
(2000)
Immunity
, vol.12
, pp. 599-609
-
-
Sprick, M.R.1
Weigand, M.A.2
Rieser, E.3
Rauch, C.T.4
Juo, P.5
Blenis, J.6
-
13
-
-
0033491193
-
CD95(APO-1/Fas)-mediated apoptosis: live and let die
-
Krammer PH (1999) CD95(APO-1/Fas)-mediated apoptosis: live and let die. Adv. Immunol. 71, 163-210.
-
(1999)
Adv. Immunol.
, vol.71
, pp. 163-210
-
-
Krammer, P.H.1
-
14
-
-
0028883850
-
Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor
-
Kischkel FC, Hellbardt S, Behrmann I, Germer M, Pawlita M, Krammer PH et al. (1995) Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor. EMBO J. 14, 5579-5588.
-
(1995)
EMBO J.
, vol.14
, pp. 5579-5588
-
-
Kischkel, F.C.1
Hellbardt, S.2
Behrmann, I.3
Germer, M.4
Pawlita, M.5
Krammer, P.H.6
-
15
-
-
80054839348
-
Cell death pathology: cross-talk with autophagy and its clinical implications
-
Ivano A, Gerry M, Richard AK (2011) Cell death pathology: cross-talk with autophagy and its clinical implications. Biochem. Biophys. Res. Commun. 414, 277-281.
-
(2011)
Biochem. Biophys. Res. Commun.
, vol.414
, pp. 277-281
-
-
Ivano, A.1
Gerry, M.2
Richard, A.K.3
-
16
-
-
0032522738
-
IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases
-
Deveraux QL, Roy N, Stennicke HR, Arsdale TV (1998) IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases. EMBO J. 17, 2215-2223.
-
(1998)
EMBO J.
, vol.17
, pp. 2215-2223
-
-
Deveraux, Q.L.1
Roy, N.2
Stennicke, H.R.3
Arsdale, T.V.4
-
17
-
-
0030925774
-
FLICE is activated by association with the CD95 death-inducing signaling complex (DISC)
-
Medema JP, Scaffidi C, Kischkel FC, Shevchenko A, Mann M, Krammer PH et al. (1997) FLICE is activated by association with the CD95 death-inducing signaling complex (DISC). EMBO J. 16, 2794-2804.
-
(1997)
EMBO J.
, vol.16
, pp. 2794-2804
-
-
Medema, J.P.1
Scaffidi, C.2
Kischkel, F.C.3
Shevchenko, A.4
Mann, M.5
Krammer, P.H.6
-
18
-
-
79952240840
-
Understanding the Role of the Death Receptor 5/FADD/caspase-8 Death Signaling in Cancer Metastasis
-
Sun S (2011) Understanding the Role of the Death Receptor 5/FADD/caspase-8 Death Signaling in Cancer Metastasis. Mol. Cell. Pharmacol. 3, 31-34.
-
(2011)
Mol. Cell. Pharmacol.
, vol.3
, pp. 31-34
-
-
Sun, S.1
-
19
-
-
0034722884
-
Bcl-2 family proteins as targets for anticancer drug design
-
Huang Z (2000) Bcl-2 family proteins as targets for anticancer drug design. Oncogene 19, 6627-6631.
-
(2000)
Oncogene
, vol.19
, pp. 6627-6631
-
-
Huang, Z.1
-
20
-
-
41149152733
-
How do BCL-2 proteins induce mitochondrial outer membrane permeabilization
-
Chipuk JE, Green DR (2008) How do BCL-2 proteins induce mitochondrial outer membrane permeabilization. Trends Cell Biol. 18, 157-164.
-
(2008)
Trends Cell Biol.
, vol.18
, pp. 157-164
-
-
Chipuk, J.E.1
Green, D.R.2
-
21
-
-
0030715323
-
Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
-
Li P, Nijhawan D, Budihardjo I, Srinivasula SM, Ahmad M, Alnemri ES et al. (1997) Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 91, 479-489.
-
(1997)
Cell
, vol.91
, pp. 479-489
-
-
Li, P.1
Nijhawan, D.2
Budihardjo, I.3
Srinivasula, S.M.4
Ahmad, M.5
Alnemri, E.S.6
-
22
-
-
68049143304
-
Caspase genes apoptosis and cancer: mutations within caspase genes
-
Ghavami S, Hashemi M, Ande SR, Yeganeh B, Xiao W, Eshraghi M et al. (2009) Caspase genes apoptosis and cancer: mutations within caspase genes. J. Med. Genet. 46, 497-510.
-
(2009)
J. Med. Genet.
, vol.46
, pp. 497-510
-
-
Ghavami, S.1
Hashemi, M.2
Ande, S.R.3
Yeganeh, B.4
Xiao, W.5
Eshraghi, M.6
-
23
-
-
0032493910
-
Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase-9
-
Kuida K, Haydar TF, Kuan CY et al. (1998) Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase-9. Cell 94, 325-337.
-
(1998)
Cell
, vol.94
, pp. 325-337
-
-
Kuida, K.1
Haydar, T.F.2
Kuan, C.Y.3
-
24
-
-
17644387220
-
Protein kinase A regulates caspase-9 activation by Apaf-1 downstream of cytochrome c
-
Martin MC, Allan LA, Lickrish M, Sampson C, Morrice N, Clarke PR (2005) Protein kinase A regulates caspase-9 activation by Apaf-1 downstream of cytochrome c. J. Biol. Chem. 280, 15449-15455.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 15449-15455
-
-
Martin, M.C.1
Allan, L.A.2
Lickrish, M.3
Sampson, C.4
Morrice, N.5
Clarke, P.R.6
-
25
-
-
70349956567
-
Apoptosis and autophagy: regulation of caspase-9 by phosphorylation
-
Allan LA, Clarke PR (2009) Apoptosis and autophagy: regulation of caspase-9 by phosphorylation. FEBS J. 276, 6063-6073.
-
(2009)
FEBS J.
, vol.276
, pp. 6063-6073
-
-
Allan, L.A.1
Clarke, P.R.2
-
26
-
-
70350574128
-
The role of protein synthesis in cell cycling and cancer
-
Shai WG, David TK, Christina VJ (2009) The role of protein synthesis in cell cycling and cancer. Mol. Oncol. 3, 402-408.
-
(2009)
Mol. Oncol.
, vol.3
, pp. 402-408
-
-
Shai, W.G.1
David, T.K.2
Christina, V.J.3
-
28
-
-
77956680686
-
Survivin and IAP proteins in cell-death mechanisms
-
Altieri DC (2010) Survivin and IAP proteins in cell-death mechanisms. Biochem. J. 430, 199-205.
-
(2010)
Biochem. J.
, vol.430
, pp. 199-205
-
-
Altieri, D.C.1
-
29
-
-
0037291737
-
Mechanism of XIAP-mediated inhibition of caspase-9
-
Shiozaki EN, Chai J, Rigotti DJ, Riedl SJ, Li P, Srinivasula SM et al. (2003) Mechanism of XIAP-mediated inhibition of caspase-9. Mol. Cell 11, 519-527.
-
(2003)
Mol. Cell
, vol.11
, pp. 519-527
-
-
Shiozaki, E.N.1
Chai, J.2
Rigotti, D.J.3
Riedl, S.J.4
Li, P.5
Srinivasula, S.M.6
-
30
-
-
0036205587
-
Mechanisms of caspase activation and inhibition during apoptosis
-
Shi Y (2002) Mechanisms of caspase activation and inhibition during apoptosis. Mol. Cell 9, 459-470.
-
(2002)
Mol. Cell
, vol.9
, pp. 459-470
-
-
Shi, Y.1
-
31
-
-
0036022407
-
Initiator caspases in apoptosis signaling pathways
-
Chen M, Wang J (2002) Initiator caspases in apoptosis signaling pathways. Apoptosis 7, 313-319.
-
(2002)
Apoptosis
, vol.7
, pp. 313-319
-
-
Chen, M.1
Wang, J.2
-
32
-
-
77956363593
-
Autophagic pathways as new targets for cancer drug development
-
Liu B, Cheng Y, Liu Q, Bao JK, Yang JM (2010) Autophagic pathways as new targets for cancer drug development. Acta Pharmacol. Sin. 31, 1154-1164.
-
(2010)
Acta Pharmacol. Sin.
, vol.31
, pp. 1154-1164
-
-
Liu, B.1
Cheng, Y.2
Liu, Q.3
Bao, J.K.4
Yang, J.M.5
-
33
-
-
78649636176
-
Caspase-mediated cleavage of Beclin-1 inactivates Beclin-1-induced autophagy and enhances apoptosis by promoting the release of pro-apoptotic factors from mitochondria
-
Wirawan E, Vande Walle L, Kersse K, Cornelis S, Claerhout S, Vanoverberghe I et al. (2010) Caspase-mediated cleavage of Beclin-1 inactivates Beclin-1-induced autophagy and enhances apoptosis by promoting the release of pro-apoptotic factors from mitochondria. Cell Death Dis. 1, e18.
-
(2010)
Cell Death Dis.
, vol.1
-
-
Wirawan, E.1
Vande Walle, L.2
Kersse, K.3
Cornelis, S.4
Claerhout, S.5
Vanoverberghe, I.6
-
35
-
-
77950252174
-
Cross-talk between apoptosis and autophagy by caspase-mediated cleavage of Beclin-1
-
Djavaheri-Mergny M, Maiuri MC, Kroemer G (2010) Cross-talk between apoptosis and autophagy by caspase-mediated cleavage of Beclin-1. Oncogene 29, 1717-1719.
-
(2010)
Oncogene
, vol.29
, pp. 1717-1719
-
-
Djavaheri-Mergny, M.1
Maiuri, M.C.2
Kroemer, G.3
-
36
-
-
33749162486
-
H-U Simon, Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis
-
Yousefi S, Perozzo R, Schmid I, Ziemiecki A, Schaffner T, Scapozza L et al. (2006) H-U Simon, Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis. Nat. Cell Biol. 8, 1124-1132.
-
(2006)
Nat. Cell Biol.
, vol.8
, pp. 1124-1132
-
-
Yousefi, S.1
Perozzo, R.2
Schmid, I.3
Ziemiecki, A.4
Schaffner, T.5
Scapozza, L.6
-
37
-
-
77954661101
-
A systems level strategy for analyzing the cell death network: implication in exploring the apoptosis/autophagy connection
-
Zalckvar E, Yosef N, Reef S, Ber Y, Rubinstein AD, Mor I et al. (2010) A systems level strategy for analyzing the cell death network: implication in exploring the apoptosis/autophagy connection. Cell Death Differ. 17, 1244-1253.
-
(2010)
Cell Death Differ.
, vol.17
, pp. 1244-1253
-
-
Zalckvar, E.1
Yosef, N.2
Reef, S.3
Ber, Y.4
Rubinstein, A.D.5
Mor, I.6
-
38
-
-
69649090647
-
Caspase cleavage of Atg4D stimulates GABARAP-L1 processing and triggers mitochondrial targeting and apoptosis
-
Betin VM, Lane JD (2009) Caspase cleavage of Atg4D stimulates GABARAP-L1 processing and triggers mitochondrial targeting and apoptosis. J. Cell Sci. 122, 2554-2566.
-
(2009)
J. Cell Sci.
, vol.122
, pp. 2554-2566
-
-
Betin, V.M.1
Lane, J.D.2
-
39
-
-
55949083821
-
FADD and caspase-8 control the outcome of autophagic signaling in proliferating T cells
-
Bell BD, Leverrier S, Weist BM, Newton RH, Arechiga AF, Luhrs KA et al. (2008) FADD and caspase-8 control the outcome of autophagic signaling in proliferating T cells. Proc. Natl. Acad. Sci. USA. 105, 16677-16682.
-
(2008)
Proc. Natl. Acad. Sci. USA.
, vol.105
, pp. 16677-16682
-
-
Bell, B.D.1
Leverrier, S.2
Weist, B.M.3
Newton, R.H.4
Arechiga, A.F.5
Luhrs, K.A.6
-
40
-
-
79960925702
-
Core signaling pathways of survival/death in autophagy-related cancer networks
-
Wang SY, Yu QJ, Zhang RD, Liu B (2011) Core signaling pathways of survival/death in autophagy-related cancer networks. Int. J. Biochem. Cell Biol. 4, 1263-1266.
-
(2011)
Int. J. Biochem. Cell Biol.
, vol.4
, pp. 1263-1266
-
-
Wang, S.Y.1
Yu, Q.J.2
Zhang, R.D.3
Liu, B.4
-
41
-
-
84876087841
-
Caspase-8 as a therapeutic target in cancer
-
doi: 10.1016/j.canlet.2010.07.022
-
Stupack DG (2010) Caspase-8 as a therapeutic target in cancer. Cancer Lett. doi: 10.1016/j.canlet.2010.07.022
-
(2010)
Cancer Lett
-
-
Stupack, D.G.1
-
42
-
-
70349974226
-
Paclitaxel promotes a caspase 8-mediated apoptosis through death effector domain association with microtubules
-
Mielgo A, Torres VA, Clair K, Barbero S, Stupack DG (2009) Paclitaxel promotes a caspase 8-mediated apoptosis through death effector domain association with microtubules. Oncogene 28, 3551-3562.
-
(2009)
Oncogene
, vol.28
, pp. 3551-3562
-
-
Mielgo, A.1
Torres, V.A.2
Clair, K.3
Barbero, S.4
Stupack, D.G.5
-
43
-
-
68749110548
-
An agonistic monoclonal antibody against DR5 induces ROS production, sustained JNK activation and endo G release in Jurkat leukemia cells
-
Chen C, Liu Y, Zheng D (2009) An agonistic monoclonal antibody against DR5 induces ROS production, sustained JNK activation and endo G release in Jurkat leukemia cells. Cell Res. 19, 984-995.
-
(2009)
Cell Res.
, vol.19
, pp. 984-995
-
-
Chen, C.1
Liu, Y.2
Zheng, D.3
-
44
-
-
35649021739
-
NOS2 regulation of NF-kappaB by S-nitrosylation of p65
-
Kelleher ZT, Matsumoto A, Stamler JS, Marshall HE (2007) NOS2 regulation of NF-kappaB by S-nitrosylation of p65. J. Biol. Chem. 282, 30667-30672.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 30667-30672
-
-
Kelleher, Z.T.1
Matsumoto, A.2
Stamler, J.S.3
Marshall, H.E.4
-
45
-
-
38949125853
-
Combination of proteasome inhibitors bortezomib and NPI-0052 trigger in vivo synergistic cytotoxicity in multiple myeloma
-
Chauhan D, Singh A, Brahmandam M et al. (2008) Combination of proteasome inhibitors bortezomib and NPI-0052 trigger in vivo synergistic cytotoxicity in multiple myeloma. Blood 111, 1654-1664.
-
(2008)
Blood
, vol.111
, pp. 1654-1664
-
-
Chauhan, D.1
Singh, A.2
Brahmandam, M.3
-
46
-
-
0034662625
-
Loss of caspase-8 expression in highly malignant human neuroblastoma cells correlates with resistance to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis
-
Hopkins-Donaldson S, Bodmer JL, Bourloud KB, Brognara CB, Tschopp J, Gross N (2000) Loss of caspase-8 expression in highly malignant human neuroblastoma cells correlates with resistance to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis. Cancer Res. 60, 4315-4319.
-
(2000)
Cancer Res.
, vol.60
, pp. 4315-4319
-
-
Hopkins-Donaldson, S.1
Bodmer, J.L.2
Bourloud, K.B.3
Brognara, C.B.4
Tschopp, J.5
Gross, N.6
-
47
-
-
65449171589
-
Fenretinide-induced caspase-8 activation and apoptosis in an established model of metastatic neuroblastoma
-
Raguénez G, Mühlethaler-Mottet A, Meier R, Duros C, Bénard J, Gross N (2009) Fenretinide-induced caspase-8 activation and apoptosis in an established model of metastatic neuroblastoma. BMC Cancer 9, 97.
-
(2009)
BMC Cancer
, vol.9
, pp. 97
-
-
Raguénez, G.1
Mühlethaler-Mottet, A.2
Meier, R.3
Duros, C.4
Bénard, J.5
Gross, N.6
-
48
-
-
10744230535
-
Heterogeneous role of caspase-8 in fenretinide-induced apoptosis in epithelial ovarian carcinoma cell lines
-
Kalli KR, Devine KE, Cabot MC, Arnt CR, Heldebrant MP, Svingen PA et al. (2003) Heterogeneous role of caspase-8 in fenretinide-induced apoptosis in epithelial ovarian carcinoma cell lines. Mol. Pharmacol. 64, 1434-1443.
-
(2003)
Mol. Pharmacol.
, vol.64
, pp. 1434-1443
-
-
Kalli, K.R.1
Devine, K.E.2
Cabot, M.C.3
Arnt, C.R.4
Heldebrant, M.P.5
Svingen, P.A.6
-
49
-
-
85047697543
-
Ablation of microvessels in vivo upon dimerization of iCaspase-9
-
Nör JE, Hu Y, Song W, Spencer DM, Núñez G (2002) Ablation of microvessels in vivo upon dimerization of iCaspase-9. Gene Ther. 9, 444-451.
-
(2002)
Gene Ther.
, vol.9
, pp. 444-451
-
-
Nör, J.E.1
Hu, Y.2
Song, W.3
Spencer, D.M.4
Núñez, G.5
-
50
-
-
0033545294
-
RGD peptides induce apoptosis by direct caspase-3 activation
-
Buckley CD, Pilling D, Henriquez NV, Parsonage G, Threlfall K, Scheel-Toellner D et al. (1999) RGD peptides induce apoptosis by direct caspase-3 activation. Nature 397, 534-539.
-
(1999)
Nature
, vol.397
, pp. 534-539
-
-
Buckley, C.D.1
Pilling, D.2
Henriquez, N.V.3
Parsonage, G.4
Threlfall, K.5
Scheel-Toellner, D.6
-
51
-
-
78649634631
-
Targeting apoptotic and autophagic pathways for cancer therapeutics
-
Liu JJ, Lin M, Yu JY, Liu B, Bao JK (2011) Targeting apoptotic and autophagic pathways for cancer therapeutics. Cancer Lett. 300, 105-114.
-
(2011)
Cancer Lett.
, vol.300
, pp. 105-114
-
-
Liu, J.J.1
Lin, M.2
Yu, J.Y.3
Liu, B.4
Bao, J.K.5
-
52
-
-
0035866793
-
Adenovirus-mediated transfer of inducible caspases: a novel 'death switch' gene therapeutic approach to prostate cancer
-
Shariat SF, Desai S, Song W, Khan T, Zhao J, Nguyen C et al. (2001) Adenovirus-mediated transfer of inducible caspases: a novel 'death switch' gene therapeutic approach to prostate cancer. Cancer Res. 61, 2562-2571.
-
(2001)
Cancer Res.
, vol.61
, pp. 2562-2571
-
-
Shariat, S.F.1
Desai, S.2
Song, W.3
Khan, T.4
Zhao, J.5
Nguyen, C.6
-
53
-
-
77953596759
-
Brucea javanica oil induces apoptosis in T24 bladder cancer cells via upregulation of caspase-3, caspase-9, and inhibition of NF-kappa B and COX-2 expressions
-
Lou GG, Yao HP, Xie LP (2010) Brucea javanica oil induces apoptosis in T24 bladder cancer cells via upregulation of caspase-3, caspase-9, and inhibition of NF-kappa B and COX-2 expressions. Am. J. Chin. Med. 38, 613-624.
-
(2010)
Am. J. Chin. Med.
, vol.38
, pp. 613-624
-
-
Lou, G.G.1
Yao, H.P.2
Xie, L.P.3
-
54
-
-
78649636534
-
Combined treatment with the Cox-2 inhibitor niflumic acid and PPARγ ligand ciglitazone induces ER stress/caspase-8-mediated apoptosis in human lung cancer cells
-
Kim BM, Maeng K, Lee KH, Hong SH (2011) Combined treatment with the Cox-2 inhibitor niflumic acid and PPARγ ligand ciglitazone induces ER stress/caspase-8-mediated apoptosis in human lung cancer cells. Cancer Lett. 300, 134-144.
-
(2011)
Cancer Lett.
, vol.300
, pp. 134-144
-
-
Kim, B.M.1
Maeng, K.2
Lee, K.H.3
Hong, S.H.4
-
55
-
-
79951680794
-
Tetrandrine induces apoptosis and triggers caspase cascade in human bladder cancer cells
-
Li X, Su B, Liu R, Wu D, He D (2011) Tetrandrine induces apoptosis and triggers caspase cascade in human bladder cancer cells. J. Surg. Res. 166, e45-e51.
-
(2011)
J. Surg. Res.
, vol.166
-
-
Li, X.1
Su, B.2
Liu, R.3
Wu, D.4
He, D.5
-
56
-
-
67650688146
-
Targeting the DNA damage response in cancer
-
Ljungman M (2009) Targeting the DNA damage response in cancer. Chem. Rev. 109, 2929-2950.
-
(2009)
Chem. Rev.
, vol.109
, pp. 2929-2950
-
-
Ljungman, M.1
-
57
-
-
34548183836
-
Poly (ADP-ribosyl) ation and cancer
-
Miwa M, Masutani M (2007) Poly (ADP-ribosyl) ation and cancer. Cancer 98, 1528-1535.
-
(2007)
Cancer
, vol.98
, pp. 1528-1535
-
-
Miwa, M.1
Masutani, M.2
-
58
-
-
0034597569
-
Resistance-modifying agents. 9. Synthesis and biological properties of benzimidazole inhibitors of the DNA repair enzyme poly(ADP-ribose) polymerase
-
White AW, Almassy R, Calvert AH, Curtin NJ, Griffin RJ, Hostomsky Z et al. (2000) Resistance-modifying agents. 9. Synthesis and biological properties of benzimidazole inhibitors of the DNA repair enzyme poly(ADP-ribose) polymerase. J. Med. Chem. 43, 4084-4097.
-
(2000)
J. Med. Chem.
, vol.43
, pp. 4084-4097
-
-
White, A.W.1
Almassy, R.2
Calvert, A.H.3
Curtin, N.J.4
Griffin, R.J.5
Hostomsky, Z.6
-
59
-
-
77953764486
-
Evolution of poly (ADP-ribose) polymerase-1(PARP-1) inhibitors. from concept to clinic
-
Ferraris DV (2010) Evolution of poly (ADP-ribose) polymerase-1(PARP-1) inhibitors. from concept to clinic. J. Med. Chem. 53, 4561-4584.
-
(2010)
J. Med. Chem.
, vol.53
, pp. 4561-4584
-
-
Ferraris, D.V.1
-
60
-
-
20244389572
-
Phthalazinones, Part 1: the design and synthesis of a series of novel potential inhibitors of poly (ADP-ribose) polymerase
-
Loh VM Jr, Cockcroft XL, Dillon KJ, Dixon L, Drzewiecki J, Eversley PJ et al. (2005) Phthalazinones, Part 1: the design and synthesis of a series of novel potential inhibitors of poly (ADP-ribose) polymerase. Bioorg. Med. Chem. Lett. 15, 2235-2238.
-
(2005)
Bioorg. Med. Chem. Lett.
, vol.15
, pp. 2235-2238
-
-
Loh Jr., V.M.1
Cockcroft, X.L.2
Dillon, K.J.3
Dixon, L.4
Drzewiecki, J.5
Eversley, P.J.6
-
61
-
-
33947719279
-
Potential therapeutic applications of autophagy
-
Rubinsztein DC, Gestwicki JE, Murphy LO, Klionsky DJ (2007) Potential therapeutic applications of autophagy. Nat. Rev. Drug Discov. 6, 304-312.
-
(2007)
Nat. Rev. Drug Discov.
, vol.6
, pp. 304-312
-
-
Rubinsztein, D.C.1
Gestwicki, J.E.2
Murphy, L.O.3
Klionsky, D.J.4
-
62
-
-
54249107573
-
Cancer cells regulation of estrogenic effects by Beclin 1 in breast
-
John S, Nayvelt I, Hsu HC et al. (2008) Cancer cells regulation of estrogenic effects by Beclin 1 in breast. Cancer Res. 68, 7855-7863.
-
(2008)
Cancer Res.
, vol.68
, pp. 7855-7863
-
-
John, S.1
Nayvelt, I.2
Hsu, H.C.3
|