Subsite-based alterations in miR-21, miR-125b, and miR-203 in squamous cell carcinoma of the oral cavity and correlation to important target proteins

Journal of Carcinogenesis

Volumn 11, Issue , 2012, Pages

  Boldrup, Linda ^a   Coates, Philip ^b   Wahlgren, Magnus ^a   Laurell, Göran ^a   Nylander, Karin ^a  

^a UMEÅ UNIVERSITY   (Sweden)

^b UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

MicroRNA; oral squamous cell carcinoma; p53; p63

Indexed keywords

MICRORNA; MICRORNA 125B; MICRORNA 203; MICRORNA 21; PROTEIN P53; PROTEIN P63; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; DOWN REGULATION; FEMALE; GINGIVA TUMOR; HUMAN; HUMAN TISSUE; IN VITRO STUDY; MALE; MOUTH SQUAMOUS CELL CARCINOMA; MUTATION; PROTEIN EXPRESSION; PROTEIN TARGETING; TONGUE TUMOR;

EID: 84872743484     PISSN: 09746773     EISSN: 14773163     Source Type: Journal    
DOI: 10.4103/1477-3163.104007     Document Type: Article

References (42)

1. Lam L, Logan RM, Luke C, Rees GL. Retrospective study of survival and treatment pattern in a cohort of patients with oral and oropharyngeal tongue cancers from 1987 to 2004. Oral Oncol 2007;43:150-8. (Pubitemid 46176703)
2. Nylander K, Dabelsteen E, Hall PA. The p53 molecule and its prognostic role in squamous cell carcinomas of the head and neck. J Oral Pathol Med 2000;29:413-25.
3. Bockmhl U, Schwendel A, Dietel M, Petersen I. Distinct patterns of chromosomal alterations in high-and low-grade head and neck squamous cell carcinomas. Cancer Res 1996;56:5325-9. (Pubitemid 27011356)
4. Yang A, McKeon F. P63 and P73: P53 mimics, menaces and more. Nat Rev Mol Cell Biol 2000;1:199-207.
5. Yang A, Kaghad M, Wang Y, Gillett E, Fleming MD, Dtsch V, et al. p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities. Mol Cell 1998;2:305-16. (Pubitemid 128379271)
6. Hibi K, Trink B, Patturajan M, Westra WH, Caballero OL, Hill DE, et al. AIS is an oncogene amplified in squamous cell carcinoma. Proc Natl Acad Sci USA 2000;97:5462-7. (Pubitemid 30313741)
7. Sniezek JC, Matheny KE, Westfall MD, Pietenpol JA. Dominant negative p63 isoform expression in head and neck squamous cell carcinoma. Laryngoscope 2004;114:2063-72. (Pubitemid 39602468)
8. Thurfjell N, Coates PJ, Uusitalo T, Mahani D, Dabelsteen E, Dahlqvist A,et al. Complex p63 mRNA isoform expression patterns in squamous cell carcinoma of the head and neck. Int J Oncol 2004;25:27-35.
9. Weber A, Bellmann U, Bootz F, Wittekind C, Tannapfel A. Expression of p53 and its homologues in primary and recurrent squamous cell carcinomas of the head and neck. Int J Cancer 2002;99:22-8. (Pubitemid 34273193)
10. Lo Muzio L, Santarelli A, Caltabiano R, Rubini C, Pieramici T, Trevisiol L,et al. p63 overexpression associates with poor prognosis in head and neck squamous cell carcinoma. Hum Pathol 2005;36:187-94. (Pubitemid 40313576)
11. Thurfjell N, Coates PJ, Vojtesek B, Benham-Motlagh P, Eisold M, Nylander K. Endogenous p63 acts as a survival factor for tumour cells of SCCHN origin. Int J Mol Med 2005;16:1065-70.
12. Boldrup L, Coates PJ, Laurell G, Nylander K. Differences in p63 expression in SCCHN tumours of different sub-sites within the oral cavity. Oral Oncol 2011;47:861-5.
13. Bartel DP. MicroRNAs: Genomics, biogenesis, mechanism, and function. Cell 2004;116:281-97.
14. He L, Hannon GJ. MicroRNAs: Small RNAs with a big role in gene regulation. Nat Rev Genet 2004;5:522-31. (Pubitemid 38868508)
15. Huang V, Place RF, Portnoy V, Wang J, Qi Z, Jia Z, et al. Upregulation of cyclin B1 by miRNA and its implications in cancer. Nucleic Acids Res 2012;40:1695-707.
16. Vasudevan S, Tong Y, Steitz JA. Switching from repression to activation: MicroRNAs can up-regulate translation. Science 2007;318:1931-4.
17. Cai X, Hagedorn CH, Cullen BR. Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs. RNA 2004;10:1957-66. (Pubitemid 39557833)
18. Chan JA, Krichevsky AM, Kosik KS. MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells. Cancer Res 2005;65:6029-33. (Pubitemid 40994386)
19. Iorio MV, Ferracin M, Liu CG, Veronese A, Spizzo R, Sabbioni S, et al. MicroRNA gene expression deregulation in human breast cancer. Cancer Res 2005;65:7065-70. (Pubitemid 41161233)
20. Lawrie CH, Gal S, Dunlop HM, Pushkaran B, Liggins AP, Pulford K, et al. Detection of elevated levels of tumour-associated microRNAs in serum of patients with diffuse large B-cell lymphoma. Br J Haematol 2008;141:672-5. (Pubitemid 351667616)
21. Nam EJ, Yoon H, Kim SW, Kim H, Kim YT, Kim JH, et al. MicroRNA expression profiles in serous ovarian carcinoma. Clin Cancer Res 2008;14:2690-5.
22. Volinia S, Calin GA, Liu CG, Ambs S, Cimmino A, Petrocca F, et al. A microRNA expression signature of human solid tumors defines cancer gene targets. Proc Natl Acad Sci USA 2006;103:2257-61. (Pubitemid 43271657)
23. Rentoft M, Fahln J, Coates PJ, Laurell G, Sjstrm B, Rydn P, et al. miRNA analysis of formalin-fixed squamous cell carcinomas of the tongue is affected by age of the samples. Int J Oncol 2011;38:61-9.
24. Chang SS, Jiang WW, Smith I, Poeta LM, Begum S, Glazer C, et al. MicroRNA alterations in head and neck squamous cell carcinoma. Int J Cancer 2008;123:2791-7.
25. Li J, Huang H, Sun L, Yang M, Pan C, Chen W, et al. MiR-21 indicates poor prognosis in tongue squamous cell carcinomas as an apoptosis inhibitor. Clin Cancer Res 2009;15:3998-4008.
26. Papagiannakopoulos T, Shapiro A, Kosik KS. MicroRNA-21 targets a network of key tumor-suppressive pathways in glioblastoma cells. Cancer Res 2008;68:8164-72.
27. Le MT, Teh C, Shyh-Chang N, Xie H, Zhou B, Korzh V, et al. MicroRNA-125b is a novel negative regulator of p53. Genes Dev 2009;23:862-76.
28. Hui AB, Lenarduzzi M, Krushel T, Waldron L, Pintilie M, Shi W, et al. Comprehensive MicroRNA profiling for head and neck squamous cell carcinomas. Clin Cancer Res 2010;16:1129-39.
29. Ramdas L, Giri U, Ashorn CL, Coombes KR, El-Naggar A, Ang KK, et al. miRNA expression profiles in head and neck squamous cell carcinoma and adjacent normal tissue. Head Neck 2009;31:642-54.
30. Henson BJ, Bhattacharjee S, ODee DM, Feingold E, Gollin SM. Decreased expression of miR-125b and miR-100 in oral cancer cells contributes to malignancy. Genes Chromosomes Cancer 2009;48:569-82.
31. Lena AM, Shalom-Feuerstein R, Rivetti di Val Cervo P, Aberdam D, Knight RA, Melino G, et al. miR-203 represses stemness by repressing DeltaNp63. Cell Death Differ 2008;15:1187-95. (Pubitemid 351850972)
32. Sonkoly E, Wei T, Janson PC, Sf A, Lundeberg L, Tengvall-Linder M, et al. MicroRNAs: Novel regulators involved in the pathogenesis of psoriasis? PLoS One 2007;2 :e0 610.
33. Yi R, Poy MN, Stoffel M, Fuchs E. A skin microRNA promotes differentiation by repressing stemness. Nature 2008;452:225-9. (Pubitemid 351380241)
34. Liu X, Jiang L, Wang A, Yu J, Shi F, Zhou X. MicroRNA-138 suppresses invasion and promotes apoptosis in head and neck squamous cell carcinoma cell lines. Cancer Lett 2009;286:217-22.
35. Kozaki K, Imoto I, Mogi S, Omura K, Inazawa J. Exploration of tumor-suppressive microRNAs silenced by DNA hypermethylation in oral cancer. Cancer Res 2008;68:2094-105. (Pubitemid 351521781)
36. Baek D, Villn J, Shin C, Camargo FD, Gygi SP, Bartel DP. The impact of microRNAs on protein output. Nature 2008;455:64-71.
37. Guo H, Ingolia NT, Weissman JS, Bartel DP. Mammalian microRNAs predominantly act to decrease target mRNA levels. Nature 2010;466:835-40.
38. Nenutil R, Smardova J, Pavlova S, Hanzelkova Z, Muller P, Fabian P, et al. Discriminating functional and non-functional p53 in human tumours by p53 and MDM2 immunohistochemistry. J Pathol 2005;207:251-9. (Pubitemid 41556448)
39. Rajewsky N. MicroRNA target predictions in animals. Nat Genet 2006;38:S8-13.
40. Krek A, Grn D, Poy MN, Wolf R, Rosenberg L, Epstein EJ, et al. Combinatorial microRNA target predictions. Nat Genet 2005;37:495-500. (Pubitemid 40617277)
41. Gu X, Nylander E, Coates PJ, Nylander K. Effect of narrow-band ultraviolet B phototherapy on p63 and microRNA (miR-21 and miR-125b) expression in psoriatic epidermis. Acta Derm Venereol 2011;91:392-7.
42. Iorio MV, Croce CM. Causes and consequences of microRNA dysregulation. Cancer J 2012;18:215-2.