MicroRNA-21 targets tumor suppressor genes ANP32A and SMARCA4

Oncogene

Volumn 30, Issue 26, 2011, Pages 2975-2985

  Schramedei, K ^a   Morbt N ^b   Pfeifer, G ^a   Lauter J ^a   Rosolowski, M ^a   Tomm, J M ^b   Von Bergen, M ^b   Horn, F ^a   Brocke Heidrich, K ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

^b HELMHOLTZ CENTRE FOR ENVIRONMENTAL RESEARCH UFZ   (Germany)

Author keywords

ANP32A; miR 21; post transcriptional regulation; prostate; SMARCA4

Indexed keywords

ACIDIC NUCLEAR PHOSPHOPROTEIN 32 FAMILY MEMBER A; BRG1 PROTEIN; MICRORNA 21; PROTEIN PDCD4; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CELL VIABILITY; CHROMATIN ASSEMBLY AND DISASSEMBLY; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION; GLIOBLASTOMA; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN EXPRESSION; TWO DIMENSIONAL DIFFERENCE GEL ELECTROPHORESIS;

BASE SEQUENCE; CELL SURVIVAL; CELL TRANSFORMATION, NEOPLASTIC; CELLS, CULTURED; DNA HELICASES; DOWN-REGULATION; GENE EXPRESSION REGULATION; GENE TARGETING; GENES, TUMOR SUPPRESSOR; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICRORNAS; MOLECULAR SEQUENCE DATA; NUCLEAR PROTEINS; REGULATORY SEQUENCES, RIBONUCLEIC ACID; SEQUENCE HOMOLOGY, NUCLEIC ACID; TRANSCRIPTION FACTORS; TWO-DIMENSIONAL DIFFERENCE GEL ELECTROPHORESIS;

ALIAS;

EID: 79959843370     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2011.15     Document Type: Article

References (62)

1. Asangani IA, Rasheed SA, Nikolova DA, Leupold JH, Colburn NH, Post S et al. (2008). MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer. Oncogene 27: 2128-2136. (Pubitemid 351485639)
2. Baek D, Villen J, Shin C, Camargo FD, Gygi SP, Bartel DP. (2008). The impact of microRNAs on protein output. Nature 455: 64-71.
3. Bai J, Brody JR, Kadkol SS, Pasternack GR. (2001). Tumor suppression and potentiation by manipulation of pp32 expression. Oncogene 20: 2153-2160. (Pubitemid 32424009)
4. Bartel DP. (2004). MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116: 281-297.
5. Brennecke J, Stark A, Russell RB, Cohen SM. (2005). Principles of microRNA-target recognition. PLoS Biol 3: e85.
6. Brody JR, Kadkol SS, Mahmoud MA, Rebel JM, Pasternack GR. (1999). Identification of sequences required for inhibition of oncogene-mediated transformation by pp32. J Biol Chem 274: 20053-20055.
7. Brody JR, Witkiewicz A, Williams TK, Kadkol SS, Cozzitorto J, Durkan B et al. (2007). Reduction of pp32 expression in poorly differentiated pancreatic ductal adenocarcinomas and intraductal papillary mucinous neoplasms with moderate dysplasia. Mod Pathol 20: 1238-1244. (Pubitemid 350126858)
8. Bultman S, Gebuhr T, Yee D, La MC, Nicholson J, Gilliam A et al. (2000). A Brg1 null mutation in the mouse reveals functional differences among mammalian SWI/SNF complexes. Mol Cell 6: 1287-1295. (Pubitemid 32045922)
9. Cai X, Hagedorn CH, Cullen BR. (2004). Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs. RNA 10: 1957-1966. (Pubitemid 39557833)
10. Calin GA, Dumitru CD, Shimizu M, Bichi R, Zupo S, Noch E et al. (2002). Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proc Natl Acad Sci USA 99: 15524-15529. (Pubitemid 35403967)
11. Chan JA, Krichevsky AM, Kosik KS. (2005). MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells. Cancer Res 65: 6029-6033. (Pubitemid 40994386)
12. Chen TH, Brody JR, Romantsev FE, Yu JG, Kayler AE, Voneiff E et al. (1996). Structure of pp32, an acidic nuclear protein which inhibits oncogene-induced formation of transformed foci. Mol Biol Cell 7: 2045-2056. (Pubitemid 26415009)
13. Cohet N, Stewart KM, Mudhasani R, Asirvatham AJ, Mallappa C, Imbalzano KM et al. (2010). SWI/SNF chromatin remodeling enzyme ATPases promote cell proliferation in normal mammary epithelial cells. J Cell Physiol 223: 667-678.
14. Dunaief JL, Strober BE, Guha S, Khavari PA, Alin K, Luban J et al. (1994). The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest. Cell 79: 119-130. (Pubitemid 24309518)
15. Frankel LB, Christoffersen NR, Jacobsen A, Lindow M, Krogh A, Lund AH. (2008). Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR-21 in breast cancer cells. J Biol Chem 283: 1026-1033.
16. Fujita S, Ito T, Mizutani T, Minoguchi S, Yamamichi N, Sakurai K et al. (2008). miR-21 Gene expression triggered by AP-1 is sustained through a double-negative feedback mechanism. J Mol Biol 378: 492-504.
17. Fulci V, Chiaretti S, Goldoni M, Azzalin G, Carucci N, Tavolaro S et al. (2007). Quantitative technologies establish a novel microRNA profile of chronic lymphocytic leukemia. Blood 109: 4944-4951. (Pubitemid 46827793)
18. Gabriely G, Wurdinger T, Kesari S, Esau CC, Burchard J, Linsley PS et al. (2008). MicroRNA 21 promotes glioma invasion by targeting matrix metalloproteinase regulators. Mol Cell Biol 28: 5369-5380.
19. Garzon R, Calin GA, Croce CM. (2009). MicroRNAs in cancer. Annu Rev Med 60: 167-179.
20. Hoffarth S, Zitzer A, Wiewrodt R, Hahnel PS, Beyer V, Kreft A et al. (2008). pp32/PHAPI determines the apoptosis response of non-small-cell lung cancer. Cell Death Differ 15: 161-170. (Pubitemid 350286184)
21. Hummel M, Bentink S, Berger H, Klapper W, Wessendorf S, Barth TF et al. (2006). A biologic definition of Burkitt's lymphoma from transcriptional and genomic profiling. N Engl J Med 354: 2419-2430. (Pubitemid 43855045)
22. Huynh T, Miranda K, Tay Y, Ang Y-S, Tam W-L, Thomson AM et al. (2006). A pattern-based method for the identification of microRNA-target sites and their corresponding RNA/RNA complexes. Cell 126: 1203-1217. (Pubitemid 44380294)
23. Iorio MV, Ferracin M, Liu CG, Veronese A, Spizzo R, Sabbioni S et al. (2005). MicroRNA gene expression deregulation in human breast cancer. Cancer Res 65: 7065-7070. (Pubitemid 41161233)
24. Jehmlich N, Schmidt F, von BM, Richnow HH, Vogt C. (2008). Protein-based stable isotope probing (Protein-SIP) reveals active species within anoxic mixed cultures. ISME J 2: 1122-1133.
25. John B, Sander C, Marks DS. (2006). Prediction of human microRNA targets. Methods Mol Biol 342: 101-113.
26. Khavari PA, Peterson CL, Tamkun JW, Mendel DB, Crabtree GR. (1993). BRG1 contains a conserved domain of the SWI2/SNF2 family necessary for normal mitotic growth and transcription. Nature 366: 170-174. (Pubitemid 23351822)
27. Kiriakidou M, Nelson PT, Kouranov A, Fitziev P, Bouyioukos C, Mourelatos Z et al. (2004). A combined computational-experimental approach predicts human microRNA targets. Genes Dev 18: 1165-1178. (Pubitemid 38669037)
28. Krichevsky AM, Gabriely G. (2009). miR-21: a small multi-faceted RNA. J Cell Mol Med 13: 39-53.
29. Lauter J, Horn F, Rosolowski M, Glimm E. (2009). High-dimensional data analysis: selection of variables, data compression and graphics-application to gene expression. Biom J 51: 235-251.
30. Lawrie CH, Soneji S, Marafioti T, Cooper CD, Palazzo S, Paterson JC et al. (2007). MicroRNA expression distinguishes between germinal center B cell-like and activated B cell-like subtypes of diffuse large B cell lymphoma. Int J Cancer 121: 1156-1161. (Pubitemid 47101656)
31. Lewis BP, Shih IH, Jones-Rhoades MW, Bartel DP, Burge CB. (2003). Prediction of mammalian microRNA targets. Cell 115: 787-798. (Pubitemid 38058492)
32. Li M, Guo H, Damuni Z. (1995). Purification and characterization of two potent heat-stable protein inhibitors of protein phosphatase 2A from bovine kidney. Biochemistry 34: 1988-1996.
33. Li M, Makkinje A, Damuni Z. (1996). Molecular identification of I1PP2A, a novel potent heat-stable inhibitor protein of protein phosphatase 2A. Biochemistry 35: 6998-7002.
34. Li T, Li D, Sha J, Sun P, Huang Y. (2009). MicroRNA-21 directly targets MARCKS and promotes apoptosis resistance and invasion in prostate cancer cells. Biochem Biophys Res Commun 383: 280-285.
35. Loffler D, Brocke-Heidrich K, Pfeifer G, Stocsits C, Hackermuller J, Kretzschmar AK et al. (2007). Interleukin-6 dependent survival of multiple myeloma cells involves the Stat3-mediated induction of microRNA-21 through a highly conserved enhancer. Blood 110: 1330-1333. (Pubitemid 47281433)
36. Lu Z, Liu M, Stribinskis V, Klinge CM, Ramos KS, Colburn NH et al. (2008). MicroRNA-21 promotes cell transformation by targeting the programmed cell death 4 gene. Oncogene 27: 4373-4379. (Pubitemid 352010003)
37. Martin G, Schouest K, Kovvuru P, Spillane C. (2007). Prediction and validation of microRNA targets in animal genomes. J Biosci 32: 1049-1052. (Pubitemid 47583865)
38. Matsuoka K, Taoka M, Satozawa N, Nakayama H, Ichimura T, Takahashi N et al. (1994). A nuclear factor containing the leucine-rich repeats expressed in murine cerebellar neurons. Proc Natl Acad Sci USA 91: 9670-9674. (Pubitemid 24311869)
39. Meng F, Henson R, Lang M, Wehbe H, Maheshwari S, Mendell JT et al. (2006). Involvement of human micro-RNA in growth and response to chemotherapy in human cholangiocarcinoma cell lines. Gastroenterology 130: 2113-2129. (Pubitemid 43816961)
40. Meng F, Henson R, Wehbe-Janek H, Ghoshal K, Jacob ST, Patel T. (2007). MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer. Gastroenterology 133: 647-658. (Pubitemid 47187346)
41. Morbt N, Mogel I, Kalkhof S, Feltens R, Roder-Stolinski C, Zheng J et al. (2009). Proteome changes in human bronchoalveolar cells following styrene exposure indicate involvement of oxidative stress in the molecular-response mechanism. Proteomics 9: 4920-4933.
42. Navarro A, Gaya A, Martinez A, Urbano-Ispizua A, Pons A, Balague O et al. (2008). MicroRNA expression profiling in classic Hodgkin lymphoma. Blood 111: 2825-2832.
43. Pan W, da Graca LS, Shao Y, Yin Q, Wu H, Jiang X. (2009). PHAPI/ pp32 suppresses tumorigenesis by stimulating apoptosis. J Biol Chem 284: 6946-6954.
44. Papagiannakopoulos T, Shapiro A, Kosik KS. (2008). MicroRNA-21 targets a network of key tumor-suppressive pathways in glioblas-toma cells. Cancer Res 68: 8164-8172.
45. Reisman D, Glaros S, Thompson EA. (2009). The SWI/SNF complex and cancer. Oncogene 28: 1653-1668.
46. Rodriguez-Nieto S, Sanchez-Cespedes M. (2009). BRG1 and LKB1: tales of two tumor suppressor genes on chromosome 19p and lung cancer. Carcinogenesis 30: 547-554.
47. Rosenwald A, Wright G, Chan WC, Connors JM, Campo E, Fisher RI et al. (2002). The use of molecular profiling to predict survival after chemotherapy for diffuse large-B-cell lymphoma. N Engl J Med 346: 1937-1947. (Pubitemid 34651353)
48. Santos PM, Roma V, Benndorf D, von BM, Harms H, Sa-Correia I. (2007). Mechanistic insights into the global response to phenol in the phenol-biodegrading strain Pseudomonas sp. M1 revealed by quantitative proteomics. OMICS 11: 233-251. (Pubitemid 47463367)
49. Selbach M, Schwanhausser B, Thierfelder N, Fang Z, Khanin R, Rajewsky N. (2008). Widespread changes in protein synthesis induced by microRNAs. Nature 455: 58-63.
50. Selcuklu SD, Donoghue MT, Spillane C. (2009). miR-21 as a key regulator of oncogenic processes. Biochem Soc Trans 37: 918-925.
51. Seo SB, McNamara P, Heo S, Turner A, Lane WS, Chakravarti D. (2001). Regulation of histone acetylation and transcription by INHAT, a human cellular complex containing the set oncoprotein. Cell 104: 119-130. (Pubitemid 32144977)
52. Sethupathy P, Megraw M, Hatzigeorgiou AG. (2006). A guide through present computational approaches for the identification of mammalian microRNA targets. Nat Methods 3: 881-886. (Pubitemid 44614721)
53. Strober BE, Dunaief JL, Guha S, Goff SP. (1996). Functional interactions between the hBRM/hBRG1 transcriptional activators and the pRB family of proteins. Mol Cell Biol 16: 1576-1583. (Pubitemid 26095629)
54. Ulitzur N, Humbert M, Pfeffer SR. (1997). Mapmodulin: a possible modulator of the interaction of microtubule-associated proteins with microtubules. Proc Natl Acad Sci USA 94: 5084-5089.
55. Vaesen M, Barnikol-Watanabe S, Gotz H, Awni LA, Cole T, Zimmermann B et al. (1994). Purification and characterization of two putative HLA class II associated proteins: PHAPI and PHAPII. Biol Chem Hoppe Seyler 375: 113-126. (Pubitemid 2052263)
56. Volinia S, Calin GA, Liu CG, Ambs S, Cimmino A, Petrocca F et al. (2006). A microRNA expression signature of human solid tumors defines cancer gene targets. Proc Natl Acad Sci USA 103: 2257-2261. (Pubitemid 43271657)
57. Wong AK, Shanahan F, Chen Y, Lian L, Ha P, Hendricks K et al. (2000). BRG1, a component of the SWI-SNF complex, is mutated in multiple human tumor cell lines. Cancer Res 60: 6171-6177.
58. Xiao F, Zuo Z, Cai G, Kang S, Gao X, Li T. (2009). miRecords: an integrated resource for microRNA-target interactions. Nucleic Acids Res 37: D105.
59. Yang Y, Chaerkady R, Beer MA, Mendell JT, Pandey A. (2009). Identification of miR-21 targets in breast cancer cells using a quantitative proteomic approach. Proteomics 9: 1374-1384.
60. Yang Y, Chaerkady R, Kandasamy K, Huang TC, Selvan LD, Dwivedi SB et al. (2010). Identifying targets of miR-143 using a SILAC-based proteomic approach. Mol Biosyst 6: 1873-1882.
61. Yao Q, Xu H, Zhang QQ, Zhou H, Qu LH. (2009). MicroRNA-21 promotes cell proliferation and down-regulates the expression of programmed cell death 4 (PDCD4) in HeLa cervical carcinoma cells. Biochem Biophys Res Commun 388: 539-542.
62. Zhu S, Wu H, Wu F, Nie D, Sheng S, Mo YY. (2008). MicroRNA-21 targets tumor suppressor genes in invasion and metastasis. Cell Res 18: 350-359. (Pubitemid 351333899)