-
1
-
-
80052410901
-
Curcumin suppresses proliferation and induces apoptosis in human biliary cancer cells through modulation of multiple cell signaling pathways
-
21325634 10.1093/carcin/bgr032 1:CAS:528:DC%2BC3MXhtFehtb3L
-
Prakobwong SG, Gupta SC, Kim JH, Sung B, Pinlaor P, Hiraku Y, Wongkham S, Sripa B, Pinlaor S, Aggarwal BB (2011) Curcumin suppresses proliferation and induces apoptosis in human biliary cancer cells through modulation of multiple cell signaling pathways. Carcinogenesis 32:1372-1380
-
(2011)
Carcinogenesis
, vol.32
, pp. 1372-1380
-
-
Prakobwong, S.G.1
Gupta, S.C.2
Kim, J.H.3
Sung, B.4
Pinlaor, P.5
Hiraku, Y.6
Wongkham, S.7
Sripa, B.8
Pinlaor, S.9
Aggarwal, B.B.10
-
2
-
-
0036201937
-
Chemopreventive and adjuvant therapeutic potential of pomegranate (Punica granatum) for human breast cancer
-
12002340 10.1023/A:1014405730585 1:CAS:528:DC%2BD38XjtlCisbc%3D
-
Kim ND, Mehta R, Yu W, Neeman I, Livney T, Amichay A, Poirier D, Nicholls P, Kirby A, Jiang W, Mansel R, Ramachandran C, Rabi T, Kaplan B, Lansky E (2002) Chemopreventive and adjuvant therapeutic potential of pomegranate (Punica granatum) for human breast cancer. Breast Cancer Res Treat 71:203-217
-
(2002)
Breast Cancer Res Treat
, vol.71
, pp. 203-217
-
-
Kim, N.D.1
Mehta, R.2
Yu, W.3
Neeman, I.4
Livney, T.5
Amichay, A.6
Poirier, D.7
Nicholls, P.8
Kirby, A.9
Jiang, W.10
Mansel, R.11
Ramachandran, C.12
Rabi, T.13
Kaplan, B.14
Lansky, E.15
-
3
-
-
34248215034
-
Oral consumption of pomegranate fruit extract inhibits growth and progression of primary lung tumors in mice
-
17389758 10.1158/0008-5472.CAN-06-3941 1:CAS:528:DC%2BD2sXksVGktrw%3D
-
Khan N, Afaq F, Kweon MH, Kim K, Mukhtar H (2007) Oral consumption of pomegranate fruit extract inhibits growth and progression of primary lung tumors in mice. Cancer Res 67:3475-3482
-
(2007)
Cancer Res
, vol.67
, pp. 3475-3482
-
-
Khan, N.1
Afaq, F.2
Kweon, M.H.3
Kim, K.4
Mukhtar, H.5
-
4
-
-
33845612815
-
Pomegranate fruit extract inhibits prosurvival pathways in human A549 lung carcinoma cells and tumor growth in athymic nude mice
-
10.1093/carcin/bgl145
-
Khan N, Hadi N, Afaq F, Syed DN, Kweon MH, Mukhtar H (2007) Pomegranate fruit extract inhibits prosurvival pathways in human A549 lung carcinoma cells and tumor growth in athymic nude mice. Carcinogenesis 1:163-173
-
(2007)
Carcinogenesis
, vol.1
, pp. 163-173
-
-
Khan, N.1
Hadi, N.2
Afaq, F.3
Syed, D.N.4
Kweon, M.H.5
Mukhtar, H.6
-
5
-
-
70350035746
-
Pomegranate fruit extract impairs invasion and motility in human breast cancer
-
19815594 10.1177/1534735409341405 1:CAS:528:DC%2BD1MXhtlagu73K
-
Khan GN, Gorin MA, Rosenthal D, Pan Q, Bao LW, Wu ZF, Newman RA, Pawlus AD, Yang P, Lansky EP, Merajver SD (2009) Pomegranate fruit extract impairs invasion and motility in human breast cancer. Integr Cancer Ther 8:242-253
-
(2009)
Integr Cancer Ther
, vol.8
, pp. 242-253
-
-
Khan, G.N.1
Gorin, M.A.2
Rosenthal, D.3
Pan, Q.4
Bao, L.W.5
Wu, Z.F.6
Newman, R.A.7
Pawlus, A.D.8
Yang, P.9
Lansky, E.P.10
Merajver, S.D.11
-
6
-
-
77955506109
-
Inhibition of NFkB and pancreatic cancer cell and tumor growth by curcumin is dependent on specificity protein down-regulation
-
20538607 10.1074/jbc.M109.095240 1:CAS:528:DC%2BC3cXpslKjtrk%3D
-
Jutooru I, Chadalapaka G, Lei P, Safe S (2010) Inhibition of NFkB and pancreatic cancer cell and tumor growth by curcumin is dependent on specificity protein down-regulation. J Biol Chem 285:25332-25344
-
(2010)
J Biol Chem
, vol.285
, pp. 25332-25344
-
-
Jutooru, I.1
Chadalapaka, G.2
Lei, P.3
Safe, S.4
-
7
-
-
77649212752
-
Pomegranate ellagitannin-derived compounds exhibit antiproliferative and anti-aromatase activity in breast cancer cells in vitro
-
10.1158/1940-6207.CAPR-08-0225 1:CAS:528:DC%2BC3cXptFOjurc%3D
-
Adams LS, Zhang Y, Seeram NP, Heber D, Chen S (2010) Pomegranate ellagitannin-derived compounds exhibit antiproliferative and anti-aromatase activity in breast cancer cells in vitro. Cancer Prev Res (Phila) 3:108-113
-
(2010)
Cancer Prev Res (Phila)
, vol.3
, pp. 108-113
-
-
Adams, L.S.1
Zhang, Y.2
Seeram, N.P.3
Heber, D.4
Chen, S.5
-
8
-
-
53249134540
-
Grape and wine polyphenols down-regulate the expression of signal transduction genes and inhibit the growth of estrogen receptor-negative MDA-MB231 tumors in nu/nu mouse xenografts
-
19083478 10.1016/j.nutres.2008.06.009 1:CAS:528:DC%2BD1cXht1egtLbJ
-
Hakimuddin F, Tiwari K, Paliyath G, Meckling K (2008) Grape and wine polyphenols down-regulate the expression of signal transduction genes and inhibit the growth of estrogen receptor-negative MDA-MB231 tumors in nu/nu mouse xenografts. Nutr Res 28:702-713
-
(2008)
Nutr Res
, vol.28
, pp. 702-713
-
-
Hakimuddin, F.1
Tiwari, K.2
Paliyath, G.3
Meckling, K.4
-
9
-
-
48549085442
-
Curcumin decreases specificity protein expression in bladder cancer cells
-
18593936 10.1158/0008-5472.CAN-07-6805 1:CAS:528:DC%2BD1cXnvFyjt70%3D
-
Chadalapaka G, Jutooru I, Chintharlapalli S, Papineni S, Smith R 3rd, Li X, Safe S (2008) Curcumin decreases specificity protein expression in bladder cancer cells. Cancer Res 68:5345-5354
-
(2008)
Cancer Res
, vol.68
, pp. 5345-5354
-
-
Chadalapaka, G.1
Jutooru, I.2
Chintharlapalli, S.3
Papineni, S.4
Smith III, R.5
Li, X.6
Safe, S.7
-
10
-
-
77952537236
-
Cancer chemoprevention by pomegranate: Laboratory and clinical evidence
-
20155621 10.1080/01635580903285064
-
Adhami VM, Khan N, Mukhtar H (2009) Cancer chemoprevention by pomegranate: laboratory and clinical evidence. Nutr Cancer 61:811-815
-
(2009)
Nutr Cancer
, vol.61
, pp. 811-815
-
-
Adhami, V.M.1
Khan, N.2
Mukhtar, H.3
-
11
-
-
84857949057
-
Oral infusion of pomegranate fruit extract inhibits prostate carcinogenesis in the TRAMP model
-
22198212 10.1093/carcin/bgr308 1:CAS:528:DC%2BC38XjtlGrsbw%3D
-
Adhami VM, Siddiqui IA, Syed DN, Lall RK, Mukhtar H (2012) Oral infusion of pomegranate fruit extract inhibits prostate carcinogenesis in the TRAMP model. Carcinogenesis 33:644-651
-
(2012)
Carcinogenesis
, vol.33
, pp. 644-651
-
-
Adhami, V.M.1
Siddiqui, I.A.2
Syed, D.N.3
Lall, R.K.4
Mukhtar, H.5
-
12
-
-
51349137454
-
Curcumin inhibits proliferation, invasion, angiogenesis and metastasis of different cancers through interaction with multiple cell signaling proteins
-
18479807 10.1016/j.canlet.2008.03.009 1:CAS:528:DC%2BD1cXhtFWlsrjM
-
Kunnumakkara AB, Anand P, Aggarwal BB (2008) Curcumin inhibits proliferation, invasion, angiogenesis and metastasis of different cancers through interaction with multiple cell signaling proteins. Cancer Lett 269:199-225
-
(2008)
Cancer Lett
, vol.269
, pp. 199-225
-
-
Kunnumakkara, A.B.1
Anand, P.2
Aggarwal, B.B.3
-
13
-
-
38349000628
-
Cancer chemoprevention through dietary antioxidants: Progress and promise
-
18154485 10.1089/ars.2007.1740 1:CAS:528:DC%2BD1cXmt1yluw%3D%3D
-
Khan N, Afaq F, Mukhtar H (2008) Cancer chemoprevention through dietary antioxidants: progress and promise. Antioxid Redox Signal 10:475-510
-
(2008)
Antioxid Redox Signal
, vol.10
, pp. 475-510
-
-
Khan, N.1
Afaq, F.2
Mukhtar, H.3
-
14
-
-
79955572744
-
Polyphenols as small molecular inhibitors of signaling cascades in carcinogenesis
-
21356239 10.1016/j.pharmthera.2011.02.004 1:CAS:528:DC%2BC3MXlsV2nu7s%3D
-
Kang NJ, Shin SH, Lee HJ, Lee KW (2011) Polyphenols as small molecular inhibitors of signaling cascades in carcinogenesis. Pharmacol Ther 130:310-324
-
(2011)
Pharmacol Ther
, vol.130
, pp. 310-324
-
-
Kang, N.J.1
Shin, S.H.2
Lee, H.J.3
Lee, K.W.4
-
15
-
-
79955463386
-
Flavonol-rich fractions of yaupon holly leaves (Ilex vomitoria, Aquifoliaceae) induce microRNA-146a and have anti-inflammatory and chemopreventive effects in intestinal myofibroblast CCD-18Co cells
-
21262328 10.1016/j.fitote.2011.01.013 1:CAS:528:DC%2BC3MXlt1Sgtrc%3D
-
Noratto GD, Kim Y, Talcott ST, Mertens-Talcott SU (2011) Flavonol-rich fractions of yaupon holly leaves (Ilex vomitoria, Aquifoliaceae) induce microRNA-146a and have anti-inflammatory and chemopreventive effects in intestinal myofibroblast CCD-18Co cells. Fitoterapia 82:557-569
-
(2011)
Fitoterapia
, vol.82
, pp. 557-569
-
-
Noratto, G.D.1
Kim, Y.2
Talcott, S.T.3
Mertens-Talcott, S.U.4
-
16
-
-
84856242855
-
Pomegranate sensitizes Tamoxifen action in ER-α positive breast cancer cells
-
21706446 10.1007/s12079-011-0138-y
-
Banerjee S, Kambhampati S, Haque I, Banerjee SK (2011) Pomegranate sensitizes Tamoxifen action in ER-α positive breast cancer cells. J Cell Commun Signal 5:317-324
-
(2011)
J Cell Commun Signal
, vol.5
, pp. 317-324
-
-
Banerjee, S.1
Kambhampati, S.2
Haque, I.3
Banerjee, S.K.4
-
17
-
-
75449090447
-
Punicic acid is an omega-5 fatty acid capableof inhibiting breast cancer proliferation
-
20043077 1:CAS:528:DC%2BC3cXitF2gt7k%3D
-
Grossmann ME, Mizuno NK, Schuster T, Cleary MP (2010) Punicic acid is an omega-5 fatty acid capableof inhibiting breast cancer proliferation. Int J Oncol 36:421-426
-
(2010)
Int J Oncol
, vol.36
, pp. 421-426
-
-
Grossmann, M.E.1
Mizuno, N.K.2
Schuster, T.3
Cleary, M.P.4
-
18
-
-
47549111139
-
Therapeutic applications of pomegranate (Punica granatum L.): A review
-
18590349
-
Jurenka J (2008) Therapeutic applications of pomegranate (Punica granatum L.): a review. Altern Med Rev 13:128-144
-
(2008)
Altern Med Rev
, vol.13
, pp. 128-144
-
-
Jurenka, J.1
-
19
-
-
11144335895
-
Anthocyanin- and hydrolyzable tannin-rich pomegranate fruit extract modulates MAPK and NF-kB pathways and inhibits skin tumorigenesis in CD-1 mice
-
15455341 10.1002/ijc.20587 1:CAS:528:DC%2BD2MXhsFWk
-
Afaq F, Saleem M, Krueger CG, Reed JD, Mukhtar H (2005) Anthocyanin- and hydrolyzable tannin-rich pomegranate fruit extract modulates MAPK and NF-kB pathways and inhibits skin tumorigenesis in CD-1 mice. Int J Cancer 113:423-433
-
(2005)
Int J Cancer
, vol.113
, pp. 423-433
-
-
Afaq, F.1
Saleem, M.2
Krueger, C.G.3
Reed, J.D.4
Mukhtar, H.5
-
20
-
-
20144381777
-
In vitro antiproliferative, apoptotic and antioxidant activities of punicalagin, ellagic acid and a total pomegranate tannin extract are enhanced in combination with other polyphenols as found in pomegranate juice
-
15936648 10.1016/j.jnutbio.2005.01.006 1:CAS:528:DC%2BD2MXltVehsLc%3D
-
Seeram NP, Adams LS, Henning SM, Niu Y, Zhang Y, Nair MG, Heber D (2005) In vitro antiproliferative, apoptotic and antioxidant activities of punicalagin, ellagic acid and a total pomegranate tannin extract are enhanced in combination with other polyphenols as found in pomegranate juice. J Nutr Biochem 16:360-367
-
(2005)
J Nutr Biochem
, vol.16
, pp. 360-367
-
-
Seeram, N.P.1
Adams, L.S.2
Henning, S.M.3
Niu, Y.4
Zhang, Y.5
Nair, M.G.6
Heber, D.7
-
21
-
-
1842423822
-
Differentiation-promoting activity of pomegranate (Punica granatum) fruit extracts in HL-60 human promyelocytic leukemia cells
-
15117547 10.1089/109662004322984644 1:CAS:528:DC%2BD2cXjtV2lsrw%3D
-
Kawaii S, Lansky EP (2004) Differentiation-promoting activity of pomegranate (Punica granatum) fruit extracts in HL-60 human promyelocytic leukemia cells. J Med Food 7:13-18
-
(2004)
J Med Food
, vol.7
, pp. 13-18
-
-
Kawaii, S.1
Lansky, E.P.2
-
22
-
-
84862331095
-
Pomegranate extract demonstrate a selective estrogen receptor modulator profile in human tumor cell lines and in vivo models of estrogen deprivation
-
21839626 10.1016/j.jnutbio.2011.03.015
-
Sreeja S, Santhosh Kumar TR, Lakshmi BS, Sreeja S (2011) Pomegranate extract demonstrate a selective estrogen receptor modulator profile in human tumor cell lines and in vivo models of estrogen deprivation. J Nutr Biochem 23:725-732
-
(2011)
J Nutr Biochem
, vol.23
, pp. 725-732
-
-
Sreeja, S.1
Santhosh Kumar, T.R.2
Lakshmi, B.S.3
Sreeja, S.4
-
23
-
-
79958214540
-
Pomegranate-mediated chemoprevention of experimental hepatocarcinogenesis involves Nrf2-regulated antioxidant mechanisms
-
21389260 10.1093/carcin/bgr045 1:CAS:528:DC%2BC3MXntFClu7o%3D
-
Bishayee A, Bhatia D, Thoppil RJ, Darvesh AS, Nevo E, Lansky EP (2011) Pomegranate-mediated chemoprevention of experimental hepatocarcinogenesis involves Nrf2-regulated antioxidant mechanisms. Carcinogenesis 32:888-896
-
(2011)
Carcinogenesis
, vol.32
, pp. 888-896
-
-
Bishayee, A.1
Bhatia, D.2
Thoppil, R.J.3
Darvesh, A.S.4
Nevo, E.5
Lansky, E.P.6
-
24
-
-
3042551491
-
Pomegranate seed oil rich in conjugated linolenic acid suppresses chemically induced colon carcinogenesis in rats
-
15182427 10.1111/j.1349-7006.2004.tb03236.x 1:CAS:528: DC%2BD2cXmtFelsr4%3D
-
Kohno H, Suzuki R, Yasui Y, Hosokawa M, Miyashita K, Tanaka T (2004) Pomegranate seed oil rich in conjugated linolenic acid suppresses chemically induced colon carcinogenesis in rats. Cancer Sci 95:481-486
-
(2004)
Cancer Sci
, vol.95
, pp. 481-486
-
-
Kohno, H.1
Suzuki, R.2
Yasui, Y.3
Hosokawa, M.4
Miyashita, K.5
Tanaka, T.6
-
25
-
-
26844566479
-
Pomegranate fruit juice for chemoprevention and chemotherapy of prostate cancer
-
16192356 10.1073/pnas.0505870102 1:CAS:528:DC%2BD2MXhtFKjsbzK
-
Malik A, Afaq F, Sarfaraz S, Adhami VM, Syed DN, Mukhtar H (2005) Pomegranate fruit juice for chemoprevention and chemotherapy of prostate cancer. Proc Natl Acad Sci USA 102:14813-14818
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 14813-14818
-
-
Malik, A.1
Afaq, F.2
Sarfaraz, S.3
Adhami, V.M.4
Syed, D.N.5
Mukhtar, H.6
-
26
-
-
34249089950
-
Akt/cAMP-responsive element binding protein/cyclin D1 network: A novel target for prostate cancer inhibition in transgenic adenocarcinoma of mouse prostate model mediated by Nexrutine, a Phellodendron amurense bark extract
-
17473212 10.1158/1078-0432.CCR-06-2974 1:CAS:528:DC%2BD2sXkslOhu70%3D
-
Kumar AP, Bhaskaran S, Ganapathy M, Crosby K, Davis MD, Kochunov P, Schoolfield J, Yeh IT, Troyer DA, Ghosh R (2007) Akt/cAMP-responsive element binding protein/cyclin D1 network: a novel target for prostate cancer inhibition in transgenic adenocarcinoma of mouse prostate model mediated by Nexrutine, a Phellodendron amurense bark extract. Clin Cancer Res 13:2784-2794
-
(2007)
Clin Cancer Res
, vol.13
, pp. 2784-2794
-
-
Kumar, A.P.1
Bhaskaran, S.2
Ganapathy, M.3
Crosby, K.4
Davis, M.D.5
Kochunov, P.6
Schoolfield, J.7
Yeh, I.T.8
Troyer, D.A.9
Ghosh, R.10
-
27
-
-
0348223971
-
Transcription factor Sp1 expression is a significant predictor of survival in human gastric cancer
-
14695137 1:CAS:528:DC%2BD3sXhtVSqurzK
-
Wang L, Wei D, Huang S, Peng Z, Le X, Wu TT, Yao J, Ajani J, Xie K (2003) Transcription factor Sp1 expression is a significant predictor of survival in human gastric cancer. Clin Cancer Res 9:6371-6380
-
(2003)
Clin Cancer Res
, vol.9
, pp. 6371-6380
-
-
Wang, L.1
Wei, D.2
Huang, S.3
Peng, Z.4
Le, X.5
Wu, T.T.6
Yao, J.7
Ajani, J.8
Xie, K.9
-
28
-
-
3042570272
-
Association between expression of transcription factor Sp1 and increased vascular endothelial growth factor expression, advanced stage, and poor survival in patients with resected gastric cancer
-
15217947 10.1158/1078-0432.CCR-03-0628 1:CAS:528:DC%2BD2cXltFWmurc%3D
-
Yao JC, Wang L, Wei D, Gong W, Hassan M, Wu TT, Mansfield P, Ajani J, Xie K (2004) Association between expression of transcription factor Sp1 and increased vascular endothelial growth factor expression, advanced stage, and poor survival in patients with resected gastric cancer. Clin Cancer Res 10:4109-4117
-
(2004)
Clin Cancer Res
, vol.10
, pp. 4109-4117
-
-
Yao, J.C.1
Wang, L.2
Wei, D.3
Gong, W.4
Hassan, M.5
Wu, T.T.6
Mansfield, P.7
Ajani, J.8
Xie, K.9
-
29
-
-
16644391541
-
Up-regulation of DNA-dependent protein kinase activity and Sp1 in colorectal cancer
-
15254745 1:CAS:528:DC%2BD2cXmvF2ru7k%3D
-
Hosoi Y, Watanabe T, Nakagawa K, Matsumoto Y, Enomoto A, Morita A, Nagawa H, Suzuki N (2004) Up-regulation of DNA-dependent protein kinase activity and Sp1 in colorectal cancer. Int J Oncol 25:461-468
-
(2004)
Int J Oncol
, vol.25
, pp. 461-468
-
-
Hosoi, Y.1
Watanabe, T.2
Nakagawa, K.3
Matsumoto, Y.4
Enomoto, A.5
Morita, A.6
Nagawa, H.7
Suzuki, N.8
-
30
-
-
36349001297
-
The oncogenic microRNA-27a targets genes that regulate specificity protein transcription factors and the G2-M checkpoint in MDA-MB-231 breast cancer cells
-
18006846 10.1158/0008-5472.CAN-07-2416 1:CAS:528:DC%2BD2sXhtlSlsLrL
-
Mertens-Talcott SU, Chintharlapalli S, Li X, Safe S (2007) The oncogenic microRNA-27a targets genes that regulate specificity protein transcription factors and the G2-M checkpoint in MDA-MB-231 breast cancer cells. Cancer Res 67:11001-11011
-
(2007)
Cancer Res
, vol.67
, pp. 11001-11011
-
-
Mertens-Talcott, S.U.1
Chintharlapalli, S.2
Li, X.3
Safe, S.4
-
31
-
-
84880328502
-
Betulinic acid decreases ER-negative breast cancer cell growth in vitro and in vivo: Role of sp transcription factors and MicroRNA-27a:ZBTB10
-
doi: 10.1002/mc.21893
-
Mertens-Talcott SU, Noratto G, Li X, Angel-Morales G, Bertoldi MC, Safe S (2012) Betulinic acid decreases ER-negative breast cancer cell growth in vitro and in vivo: role of sp transcription factors and MicroRNA-27a:ZBTB10. Mol Carcinog 10. doi: 10.1002/mc.21893
-
(2012)
Mol Carcinog
, vol.10
-
-
Mertens-Talcott, S.U.1
Noratto, G.2
Li, X.3
Angel-Morales, G.4
Bertoldi, M.C.5
Safe, S.6
-
32
-
-
34047261665
-
Betulinic acid inhibits prostate cancer growth through inhibition of specificity protein transcription factors
-
17363604 10.1158/0008-5472.CAN-06-3735 1:CAS:528:DC%2BD2sXivV2nsbw%3D
-
Chintharlapalli S, Papineni S, Ramaiah SK, Safe S (2007) Betulinic acid inhibits prostate cancer growth through inhibition of specificity protein transcription factors. Cancer Res 67:2816-2823
-
(2007)
Cancer Res
, vol.67
, pp. 2816-2823
-
-
Chintharlapalli, S.1
Papineni, S.2
Ramaiah, S.K.3
Safe, S.4
-
33
-
-
67650142347
-
Oncogenic microRNA-27a is a target for anticancer agent methyl 2-cyano-3,11-dioxo-18 beta-olean-1,12-dien-30-oate in colon cancer cell
-
19582879 10.1002/ijc.24530 1:CAS:528:DC%2BD1MXhtVGisr7N
-
Chintharlapalli S, Papineni S, Abdelrahim M, Abudayyeh A, Jutooru I, Chadalapaka G, Wu F, Mertens-Talcott S, Vanderlaag K, Cho SD et al (2009) Oncogenic microRNA-27a is a target for anticancer agent methyl 2-cyano-3,11-dioxo-18 beta-olean-1,12-dien-30-oate in colon cancer cell. Int J Cancer 125:1965-1974
-
(2009)
Int J Cancer
, vol.125
, pp. 1965-1974
-
-
Chintharlapalli, S.1
Papineni, S.2
Abdelrahim, M.3
Abudayyeh, A.4
Jutooru, I.5
Chadalapaka, G.6
Wu, F.7
Mertens-Talcott, S.8
Vanderlaag, K.9
Cho, S.D.10
-
34
-
-
80052024865
-
Betulinic acid inhibits colon cancer cell and tumor growth and induces proteasome-dependent and -independent downregulation of specificity proteins (Sp) transcription factors
-
21864401 10.1186/1471-2407-11-371 1:CAS:528:DC%2BC3MXht1SqtrfN
-
Chintharlapalli S, Papineni S, Lei P, Pathi S, Safe S (2011) Betulinic acid inhibits colon cancer cell and tumor growth and induces proteasome-dependent and -independent downregulation of specificity proteins (Sp) transcription factors. BMC Cancer 11:371
-
(2011)
BMC Cancer
, vol.11
, pp. 371
-
-
Chintharlapalli, S.1
Papineni, S.2
Lei, P.3
Pathi, S.4
Safe, S.5
-
35
-
-
77954497664
-
MicroRNA-27a indirectly regulates estrogen receptor alpha expression and hormone responsiveness in MCF-7 breast cancer cells
-
20382698 10.1210/en.2009-1150 1:CAS:528:DC%2BC3cXnsVyqsbs%3D
-
Li X, Mertens-Talcott SU, Zhang S, Kim K, Ball J, Safe S (2010) MicroRNA-27a indirectly regulates estrogen receptor alpha expression and hormone responsiveness in MCF-7 breast cancer cells. Endocrinology 151:2462-2473
-
(2010)
Endocrinology
, vol.151
, pp. 2462-2473
-
-
Li, X.1
Mertens-Talcott, S.U.2
Zhang, S.3
Kim, K.4
Ball, J.5
Safe, S.6
-
36
-
-
79551646699
-
Pomegranate extract, a prooxidant with antiproliferative and proapoptotic activities preferentially towards carcinoma cells
-
10.2174/187152010794474000 1:CAS:528:DC%2BC3MXisFyjsbo%3D
-
Weisburg JH, Schuck AG, Silverman MS, Ovits-Levy CG, Solodokin LJ, Zuckerbraun HL, Babich H (2010) Pomegranate extract, a prooxidant with antiproliferative and proapoptotic activities preferentially towards carcinoma cells. Anti-Cancer Agents Med Chem 10:634-643
-
(2010)
Anti-Cancer Agents Med Chem
, vol.10
, pp. 634-643
-
-
Weisburg, J.H.1
Schuck, A.G.2
Silverman, M.S.3
Ovits-Levy, C.G.4
Solodokin, L.J.5
Zuckerbraun, H.L.6
Babich, H.7
-
37
-
-
77649237309
-
NF-kappaB and cancer: How intimate is this relationship
-
19823771 10.1007/s11010-009-0267-2 1:CAS:528:DC%2BC3cXitlKisbg%3D
-
Prasad S, Ravindran J, Aggarwal BB (2010) NF-kappaB and cancer: how intimate is this relationship. Mol Cell Biochem 336:25-37
-
(2010)
Mol Cell Biochem
, vol.336
, pp. 25-37
-
-
Prasad, S.1
Ravindran, J.2
Aggarwal, B.B.3
-
38
-
-
0141755271
-
The inositol 5′-phosphatase SHIP-1 and the Src kinase Lyn negatively regulate macrophage colony-stimulating factor-induced Akt activity
-
12882960 10.1074/jbc.M305021200 1:CAS:528:DC%2BD3sXnslWjsrk%3D
-
Baran CP, Tridandapani S, Helgason CD, Humphries RK, Krystal G, Marsh CB (2003) The inositol 5′-phosphatase SHIP-1 and the Src kinase Lyn negatively regulate macrophage colony-stimulating factor-induced Akt activity. J Biol Chem 278:38628-38636
-
(2003)
J Biol Chem
, vol.278
, pp. 38628-38636
-
-
Baran, C.P.1
Tridandapani, S.2
Helgason, C.D.3
Humphries, R.K.4
Krystal, G.5
Marsh, C.B.6
-
39
-
-
78049283700
-
Blocking of PI3K/AKT induces apoptosis by its effect on NF-kappaB activity in gastric carcinoma cell line SGC7901
-
20947290 10.1016/j.biopha.2010.08.008 1:CAS:528:DC%2BC3cXhtlOhsLnO
-
Chao X, Zao J, Xiao-Yi G, Li-Jun M, Tao S (2010) Blocking of PI3K/AKT induces apoptosis by its effect on NF-kappaB activity in gastric carcinoma cell line SGC7901. Biomed Pharmacother 64:600-604
-
(2010)
Biomed Pharmacother
, vol.64
, pp. 600-604
-
-
Chao, X.1
Zao, J.2
Xiao-Yi, G.3
Li-Jun, M.4
Tao, S.5
-
40
-
-
79951682474
-
Effect of quercetin and its metabolites isorhamnetin and quercetin-3-glucuronide on inflammatory gene expression: Role of miR-155
-
10.1016/j.jnutbio.2010.02.008
-
Boesch-Saadatmandia C, Loboda A, Wagnera AE, Stachurskab A, Jozkowiczb A, Dulakb J, Döringa F, Wolfframc S, Rimbacha G (2011) Effect of quercetin and its metabolites isorhamnetin and quercetin-3-glucuronide on inflammatory gene expression: role of miR-155. J Nutr Biochem 22:293-299
-
(2011)
J Nutr Biochem
, vol.22
, pp. 293-299
-
-
Boesch-Saadatmandia, C.1
Loboda, A.2
Wagnera, A.E.3
Stachurskab, A.4
Jozkowiczb, A.5
Dulakb, J.6
Döringa, F.7
Wolfframc, S.8
Rimbacha, G.9
-
41
-
-
77956290858
-
Resveratrol decreases the levels of miR-155 by upregulating miR-663, a microRNA targeting JunB and JunD
-
20622002 10.1093/carcin/bgq143 1:CAS:528:DC%2BC3cXhtFaitLrI
-
Tili E, Michaille JJ, Adair B, Alder H, Limagne E, Taccioli C, Ferracin M, Delmas D, Latruffe N, Croce CM (2010) Resveratrol decreases the levels of miR-155 by upregulating miR-663, a microRNA targeting JunB and JunD. Carcinogenesis 31:1561-1566
-
(2010)
Carcinogenesis
, vol.31
, pp. 1561-1566
-
-
Tili, E.1
Michaille, J.J.2
Adair, B.3
Alder, H.4
Limagne, E.5
Taccioli, C.6
Ferracin, M.7
Delmas, D.8
Latruffe, N.9
Croce, C.M.10
-
42
-
-
84860745555
-
Anti-inflammatory potential of allyl-isothiocyanate-role of Nrf2, NFκB and microRNA-155
-
21692985 10.1111/j.1582-4934.2011.01367.x 1:CAS:528:DC%2BC38Xos1Wlu74%3D
-
Wagner AE, Boesch-Saadatmandi C, Dose J, Schultheiss G, Rimbach G (2012) Anti-inflammatory potential of allyl-isothiocyanate-role of Nrf2, NFκB and microRNA-155. J Cell Mol Med 16:836-843
-
(2012)
J Cell Mol Med
, vol.16
, pp. 836-843
-
-
Wagner, A.E.1
Boesch-Saadatmandi, C.2
Dose, J.3
Schultheiss, G.4
Rimbach, G.5
-
43
-
-
80052273994
-
Anti-inflammatory, anti-proliferative and anti-atherosclerotic effects of quercetin in human in vitro and in vivo models
-
21601209 10.1016/j.atherosclerosis.2011.04.023 1:CAS:528: DC%2BC3MXhtFeht7vO
-
Kleemann R, Verschuren L, Morrison M, Zadelaar S, van Erk MJ, Wielinga PY, Kooistra T (2011) Anti-inflammatory, anti-proliferative and anti-atherosclerotic effects of quercetin in human in vitro and in vivo models. Atherosclerosis 218:44-52
-
(2011)
Atherosclerosis
, vol.218
, pp. 44-52
-
-
Kleemann, R.1
Verschuren, L.2
Morrison, M.3
Zadelaar, S.4
Van Erk, M.J.5
Wielinga, P.Y.6
Kooistra, T.7
-
44
-
-
79953171192
-
Elevated miR-155 promotes inflammation in cystic fibrosis by driving hyperexpression of interleukin-8
-
21282106 10.1074/jbc.M110.198390 1:CAS:528:DC%2BC3MXjslKgt74%3D
-
Bhattacharyya S, Balakathiresan N, Dalgard C, Gutti U, Armistead D, Jozwik C, Srivastava M, Pollard HB, Biswas R (2011) Elevated miR-155 promotes inflammation in cystic fibrosis by driving hyperexpression of interleukin-8. J Biol Chem 286:11604-11615
-
(2011)
J Biol Chem
, vol.286
, pp. 11604-11615
-
-
Bhattacharyya, S.1
Balakathiresan, N.2
Dalgard, C.3
Gutti, U.4
Armistead, D.5
Jozwik, C.6
Srivastava, M.7
Pollard, H.B.8
Biswas, R.9
-
45
-
-
0033788223
-
Antioxidant activity of pomegranate juice and its relationship with phenolic composition and processing
-
11052704 10.1021/jf000404a 1:CAS:528:DC%2BD3cXmsVCntLs%3D
-
Gil MI, Tomás-Baberán FA, Hess-Pierce B, Holcroft DM, Kader AA (2000) Antioxidant activity of pomegranate juice and its relationship with phenolic composition and processing. J Agric Food Chem 48:4581-4589
-
(2000)
J Agric Food Chem
, vol.48
, pp. 4581-4589
-
-
Gil, M.I.1
Tomás-Baberán, F.A.2
Hess-Pierce, B.3
Holcroft, D.M.4
Kader, A.A.5
-
46
-
-
27944495961
-
Caspase-3 activation and induction of PARP cleavage by cyclic dipeptide Cyclo(Phe-Pro) in HT-29 cells
-
16309216 1:CAS:528:DC%2BD2MXht12it7jJ
-
Brauns SC, Dealtry G, Milne P, Naude R, Van de Venter M (2005) Caspase-3 activation and induction of PARP cleavage by cyclic dipeptide Cyclo(Phe-Pro) in HT-29 cells. Anticancer Res 25:4197-4202
-
(2005)
Anticancer Res
, vol.25
, pp. 4197-4202
-
-
Brauns, S.C.1
Dealtry, G.2
Milne, P.3
Naude, R.4
Van De Venter, M.5
-
47
-
-
70349976210
-
MicroRNAs: Novel regulators in the hallmarks of human cancer
-
19464788 10.1016/j.canlet.2009.04.031 1:CAS:528:DC%2BD1MXht1Ogtb%2FL
-
Ruan K, Fang X, Ouyang G (2009) MicroRNAs: novel regulators in the hallmarks of human cancer. Cancer Lett 285:116-126
-
(2009)
Cancer Lett
, vol.285
, pp. 116-126
-
-
Ruan, K.1
Fang, X.2
Ouyang, G.3
-
48
-
-
65849319097
-
MicroRNA: A new player in breast cancer development
-
1:CAS:528:DC%2BD2sXhtlyht7%2FK
-
Wang V, Wu W (2007) MicroRNA: a new player in breast cancer development. J Cancer Mol 3:133-138
-
(2007)
J Cancer Mol
, vol.3
, pp. 133-138
-
-
Wang, V.1
Wu, W.2
-
49
-
-
80054709141
-
MiRNA biomarkers in breast cancer detection and management
-
21479130 10.7150/jca.2.116 1:CAS:528:DC%2BC3MXjvVCnu7k%3D
-
Fu SW, Chen L, Man YG (2011) miRNA biomarkers in breast cancer detection and management. J Cancer 2:116-122
-
(2011)
J Cancer
, vol.2
, pp. 116-122
-
-
Fu, S.W.1
Chen, L.2
Man, Y.G.3
-
50
-
-
77955409121
-
MicroRNAs: Potential biomarkers in cancer
-
10.1007/s12291-010-0008-z 1:CAS:528:DC%2BC3cXhslOnurs%3D
-
George GP, Mittal RD (2010) MicroRNAs: potential biomarkers in cancer. Indian J Clin Biochem 25:4-14
-
(2010)
Indian J Clin Biochem
, vol.25
, pp. 4-14
-
-
George, G.P.1
Mittal, R.D.2
-
52
-
-
53249094494
-
Pomegranate polyphenols down-regulate expression of androgen-synthesizing genes in human prostate cancer cells overexpressing the androgen receptor
-
18479901 10.1016/j.jnutbio.2007.11.006 1:CAS:528:DC%2BD1cXhtlGls7vI
-
Hong MY, Seeram NP, Heber D (2008) Pomegranate polyphenols down-regulate expression of androgen-synthesizing genes in human prostate cancer cells overexpressing the androgen receptor. J Nutr Biochem 19:848-855
-
(2008)
J Nutr Biochem
, vol.19
, pp. 848-855
-
-
Hong, M.Y.1
Seeram, N.P.2
Heber, D.3
-
53
-
-
80053609941
-
Delphinidin inhibits HER2 and Erk1/2 signaling and suppresses growth of HER2-overexpressing and triple negative breast cancer cell lines
-
Ozbaya T, Nahta R (2011) Delphinidin inhibits HER2 and Erk1/2 signaling and suppresses growth of HER2-overexpressing and triple negative breast cancer cell lines. Breast Cancer 5:143-154
-
(2011)
Breast Cancer
, vol.5
, pp. 143-154
-
-
Ozbaya, T.1
Nahta, R.2
-
54
-
-
82955178161
-
Resveratrol suppresses growth of cancer stem-like cells by inhibiting fatty acid synthase
-
21188630 10.1007/s10549-010-1300-6 1:CAS:528:DC%2BC3MXht1yktL7N
-
Pandey PR, Okuda H, Watabe M, Pai SK, Liu W, Kobayashi A, Xing F, Fukuda K, Hirota S, Sugai T, Wakabayashi G, Koeda K, Kashiwaba M, Suzuki K, Chiba T, Endo M, Fujioka T, Tanji S, Mo YY, Cao D, Wilber AC, Watabe K (2011) Resveratrol suppresses growth of cancer stem-like cells by inhibiting fatty acid synthase. Breast Cancer Res Treat 130:387-398
-
(2011)
Breast Cancer Res Treat
, vol.130
, pp. 387-398
-
-
Pandey, P.R.1
Okuda, H.2
Watabe, M.3
Pai, S.K.4
Liu, W.5
Kobayashi, A.6
Xing, F.7
Fukuda, K.8
Hirota, S.9
Sugai, T.10
Wakabayashi, G.11
Koeda, K.12
Kashiwaba, M.13
Suzuki, K.14
Chiba, T.15
Endo, M.16
Fujioka, T.17
Tanji, S.18
Mo, Y.Y.19
Cao, D.20
Wilber, A.C.21
Watabe, K.22
more..
-
55
-
-
49149114863
-
Role of MicroRNA miR-27a and miR-451 in the regulation of MDR1/P-glycoprotein expression in human cancer cells
-
18619946 10.1016/j.bcp.2008.06.007 1:CAS:528:DC%2BD1cXhtVSitbfN
-
Zhu H, Wu H, Liu X, Evans BR, Medina DJ, Liu CG, Yang JM (2008) Role of MicroRNA miR-27a and miR-451 in the regulation of MDR1/P-glycoprotein expression in human cancer cells. Biochem Pharmacol 76:582-588
-
(2008)
Biochem Pharmacol
, vol.76
, pp. 582-588
-
-
Zhu, H.1
Wu, H.2
Liu, X.3
Evans, B.R.4
Medina, D.J.5
Liu, C.G.6
Yang, J.M.7
-
56
-
-
57349146677
-
MicroRNA-27a functions as an oncogene in gastric adenocarcinoma by targeting prohibitin
-
10.1016/j.canlet.2008.08.003
-
Liu T, Tang H, Lang Y, Liu M, Li X (2009) MicroRNA-27a functions as an oncogene in gastric adenocarcinoma by targeting prohibitin. Cancer Lett 2:233-242
-
(2009)
Cancer Lett
, vol.2
, pp. 233-242
-
-
Liu, T.1
Tang, H.2
Lang, Y.3
Liu, M.4
Li, X.5
-
57
-
-
77954934314
-
Methyl 2-cyano-3,12-dioxooleana-1,9-dien-28-oate decreases specificity protein transcription factors and inhibits pancreatic tumor growth: Role of MicroRNA-27a
-
20488920 10.1124/mol.110.064451 1:CAS:528:DC%2BC3cXpsl2jtLY%3D
-
Jutooru I, Chadalapaka G, Abdelrahim M, Basha MR, Samudio I, Konopleva M, Andreeff M, Safe S (2010) Methyl 2-cyano-3,12-dioxooleana-1,9-dien-28-oate decreases specificity protein transcription factors and inhibits pancreatic tumor growth: role of MicroRNA-27a. Mol Pharmacol 78:226-236
-
(2010)
Mol Pharmacol
, vol.78
, pp. 226-236
-
-
Jutooru, I.1
Chadalapaka, G.2
Abdelrahim, M.3
Basha, M.R.4
Samudio, I.5
Konopleva, M.6
Andreeff, M.7
Safe, S.8
-
58
-
-
9144266369
-
SHIP2 is recruited to the cell membrane upon macrophage colony-stimulating factor (M-CSF) Stimulation and regulates M-CSF-induced signaling
-
15557176 1:CAS:528:DC%2BD2cXhtVShsbzN
-
Wang Y, Keogh RJ, Hunter MG, Mitchell CA, Frey RS, Javaid K, Malik AB, Schurmans S, Tridandapani S, Marsh CB (2004) SHIP2 is recruited to the cell membrane upon macrophage colony-stimulating factor (M-CSF) Stimulation and regulates M-CSF-induced signaling. J Immunol 173:6820-6830
-
(2004)
J Immunol
, vol.173
, pp. 6820-6830
-
-
Wang, Y.1
Keogh, R.J.2
Hunter, M.G.3
Mitchell, C.A.4
Frey, R.S.5
Javaid, K.6
Malik, A.B.7
Schurmans, S.8
Tridandapani, S.9
Marsh, C.B.10
-
59
-
-
84857013000
-
Therapeutic potential of SH2 domain-containing inositol-5′- phosphatase 1 (SHIP1) and SHIP2 inhibition in cancer
-
22033675 10.2119/molmed.2011.00178 1:CAS:528:DC%2BC38XptFelt70%3D
-
Fuhler GM, Brooks R, Toms B, Iyer S, Gengo EA, Park MY, Gumbleton M, Viernes DR, Chisholm JD, Kerr WG (2012) Therapeutic potential of SH2 domain-containing inositol-5′- phosphatase 1 (SHIP1) and SHIP2 inhibition in cancer. Mol Med 18:65-75
-
(2012)
Mol Med
, vol.18
, pp. 65-75
-
-
Fuhler, G.M.1
Brooks, R.2
Toms, B.3
Iyer, S.4
Gengo, E.A.5
Park, M.Y.6
Gumbleton, M.7
Viernes, D.R.8
Chisholm, J.D.9
Kerr, W.G.10
-
60
-
-
33845431274
-
SHIP1 negatively regulates proliferation of osteoclast precursors via akt-dependent alterations in D-type cyclins and p271
-
17142780 1:CAS:528:DC%2BD28Xht1Kitr3K
-
Zhou P, Kitaura H, Teitelbaum SL, Krystal G, Ross FP, Takeshita S (2006) SHIP1 negatively regulates proliferation of osteoclast precursors via akt-dependent alterations in D-type cyclins and p271. J Immunol 177:8777-8784
-
(2006)
J Immunol
, vol.177
, pp. 8777-8784
-
-
Zhou, P.1
Kitaura, H.2
Teitelbaum, S.L.3
Krystal, G.4
Ross, F.P.5
Takeshita, S.6
-
61
-
-
80054678671
-
Enzymatic and non-enzymatic activities of SHIP-1 in signal transduction and cancer
-
21672530 10.1016/j.bcp.2011.05.031 1:CAS:528:DC%2BC3MXhtlarsrbL
-
Conde C, Gloire G, Piette J (2011) Enzymatic and non-enzymatic activities of SHIP-1 in signal transduction and cancer. Biochem Pharmacol 82:1320-1334
-
(2011)
Biochem Pharmacol
, vol.82
, pp. 1320-1334
-
-
Conde, C.1
Gloire, G.2
Piette, J.3
-
62
-
-
78650191420
-
Role of SHIP in cancer
-
21056081 10.1016/j.exphem.2010.11.002 1:CAS:528:DC%2BC3cXhsFyns77L
-
Hamilton MJ, Ho VW, Kuroda E, Ruschmann J, Antignano F, Lam V, Krystal G (2011) Role of SHIP in cancer. Exp Hematol 39:2-13
-
(2011)
Exp Hematol
, vol.39
, pp. 2-13
-
-
Hamilton, M.J.1
Ho, V.W.2
Kuroda, E.3
Ruschmann, J.4
Antignano, F.5
Lam, V.6
Krystal, G.7
-
63
-
-
81555205674
-
Murine pancreatic adenocarcinoma dampens SHIP-1 expression and alters MDSC homeostasis and function
-
10.1371/journal.pone.0027729
-
Pilon-Thomas S, Nelson N, Vohra N, Jerald M, Pendleton L, Szekeres K, Ghansah T (2011) Murine pancreatic adenocarcinoma dampens SHIP-1 expression and alters MDSC homeostasis and function. PLoS one 6(11):1-10
-
(2011)
PLoS One
, vol.6
, Issue.11
, pp. 1-10
-
-
Pilon-Thomas, S.1
Nelson, N.2
Vohra, N.3
Jerald, M.4
Pendleton, L.5
Szekeres, K.6
Ghansah, T.7
|