메뉴 건너뛰기




Volumn , Issue , 2006, Pages 1-244

Toxicity testing for assessment of environmental agents: Interim report
[No Author Info available]

Author keywords

[No Author keywords available]

Indexed keywords

PUBLIC HEALTH; RISK ASSESSMENT; TOXICITY;

EID: 85052722446     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.17226/11523     Document Type: Book
Times cited : (21)

References (366)
  • 1
    • 0025004154 scopus 로고
    • An overview of prechronic and chronic toxicity/carcinogenicity experimental study designs and criteria used by the National Toxicology Program
    • Chhabra, R.S., J.E. Huff, B.S. Schwetz, and J. Selkirk. 1990. An overview of prechronic and chronic toxicity/carcinogenicity experimental study designs and criteria used by the National Toxicology Program. Environ. Health Perspect. 86:313-321.
    • (1990) Environ. Health Perspect. , vol.86 , pp. 313-321
    • Chhabra, R.S.1    Huff, J.E.2    Schwetz, B.S.3    Selkirk, J.4
  • 2
    • 0003672079 scopus 로고    scopus 로고
    • Guidelines for Neurotoxicity Risk Assessment
    • EPA/630/R-95/001F. U.S. Environmental Protection Agency, Washington, DC [online]. [accessed July 13, 2005].
    • EPA (U.S. Environmental Protection Agency). 1998. Guidelines for Neurotoxicity Risk Assessment. EPA/630/R-95/001F. U.S. Environmental Protection Agency, Washington, DC [online]. Available: http://www.epa.gov/ncea/raf/pdfs/neurotox.pdf [accessed July 13, 2005].
    • (1998)
  • 3
    • 84988957357 scopus 로고    scopus 로고
    • Guidance on Use of Genomics Data
    • Computational Toxicology Program, Office of Research and Development, Washington, DC [online]. [accessed April 21, 2005].
    • EPA (U.S. Environmental Protection Agency). 2004. Guidance on Use of Genomics Data. Computational Toxicology Program, Office of Research and Development, Washington, DC [online]. Available: http://www.epa.gov/comptox/comptoxfactsheet.html#guidance [accessed April 21, 2005].
    • (2004)
  • 4
    • 33645229436 scopus 로고    scopus 로고
    • Supplemental Guidance for Assessing Susceptibility from Early-Life Exposure to Carcinogens
    • EPA 630/R-03/003F. Risk Assessment Forum, U.S. Environmental Protection Agency, Washington, DC [online]. [accessed April 22, 2005].
    • EPA (U.S. Environmental Protection Agency). 2005. Supplemental Guidance for Assessing Susceptibility from Early-Life Exposure to Carcinogens. EPA 630/R-03/003F. Risk Assessment Forum, U.S. Environmental Protection Agency, Washington, DC [online]. Available: http://www.epa.gov/iris/children032505.pdf [accessed April 22, 2005].
    • (2005)
  • 5
    • 0242293690 scopus 로고    scopus 로고
    • Guidance for Industry: S1B Testing for Carcinogenicity of Pharmaceuticals
    • U.S. Department of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research (CDER), Center for Biologics Evaluation and Research (CBER), Washington, DC [online]. [accessed March 9, 1005].
    • FDA (Food and Drug Administration). 1997. Guidance for Industry: S1B Testing for Carcinogenicity of Pharmaceuticals. U.S. Department of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research (CDER), Center for Biologics Evaluation and Research (CBER), Washington, DC [online]. Available: http://www.fda.gov/cder/guidance/1854fnl.pdf [accessed March 9, 1005].
    • (1997)
  • 6
    • 84988979423 scopus 로고    scopus 로고
    • Guidance for Industry: Studies to Evaluate the Safety of Residues of Veterinary Drugs in Human Food: Carcinogenicity Testing VICH GL28
    • Final Guidance. U.S. Department of Health and Human Services, Food and Drug Administration, Center for Veterinary Medicine, May 24, 2004 [online]. [accessed March 9, 2005].
    • FDA (Food and Drug Administration). 2004. Guidance for Industry: Studies to Evaluate the Safety of Residues of Veterinary Drugs in Human Food: Carcinogenicity Testing VICH GL28. Final Guidance. U.S. Department of Health and Human Services, Food and Drug Administration, Center for Veterinary Medicine, May 24, 2004 [online]. Available: http://www.fda.gov/cvm/guidance/guide141.pdf [accessed March 9, 2005].
    • (2004)
  • 7
    • 1542333321 scopus 로고    scopus 로고
    • Guidance for Industry. Pharmacogenomic data submissions
    • U.S. Department of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research (CDER), Center for Biologics Evaluation and Research (CBER), Washington, DC [online]
    • FDA (Food and Drug Administration). 2005. Guidance for Industry. Pharmacogenomic data submissions. U.S. Department of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research (CDER), Center for Biologics Evaluation and Research (CBER), Washington, DC [online]. Available: http://www.fda.gov/OHRMS/DOCKETS/98fr/2003d-0497-gdl0002.pdf.
    • (2005)
  • 8
    • 0004291547 scopus 로고    scopus 로고
    • Validation and Regulatory Acceptance of Toxicological Test Methods, A Report of the ad hoc Interagency Coordinating Committee on the Validation of Alternative Methods
    • NIH Publication No. 97-3981. National Institute of Environmental Health Sciences, Research Triangle Park, NC. March 1997 [online]. [accessed March 11, 2005].
    • ICCVAM (Interagency Coordinating Committee on the Validation of Alternative Methods). 1997. Validation and Regulatory Acceptance of Toxicological Test Methods, A Report of the ad hoc Interagency Coordinating Committee on the Validation of Alternative Methods. NIH Publication No. 97-3981. National Institute of Environmental Health Sciences, Research Triangle Park, NC. March 1997 [online]. Available: http://iccvam.niehs.nih.gov/docs/guidelines/validate.pdf [accessed March 11, 2005].
    • (1997)
  • 9
    • 77954011051 scopus 로고    scopus 로고
    • Systemic Toxicity White Paper
    • Systemic Toxicity Task Force, Technical Committee on Agricultural Chemical Safety Assessment, ILSI Health Sciences Institute, Washington, DC. November 2, 2004.
    • ILSI HESI (International Life Sciences Institute Health and Environmental Sciences Institute). 2004a. Systemic Toxicity White Paper. Systemic Toxicity Task Force, Technical Committee on Agricultural Chemical Safety Assessment, ILSI Health Sciences Institute, Washington, DC. November 2, 2004.
    • (2004)
  • 10
    • 77954024250 scopus 로고    scopus 로고
    • Life Stages White Paper
    • Life Stages Task Force, Technical Committee on Agricultural Chemical Safety Assessment, ILSI Health Sciences Institute, Washington, DC. November 2, 2004.
    • ILSI HESI (International Life Sciences Institute Health and Environmental Sciences Institute). 2004b. Life Stages White Paper. Life Stages Task Force, Technical Committee on Agricultural Chemical Safety Assessment, ILSI Health Sciences Institute, Washington, DC. November 2, 2004.
    • (2004)
  • 11
    • 77953983251 scopus 로고    scopus 로고
    • The Acquisition and Application of Absorption, Distribution, Metabolism, and Excretion (ADME) Data in Agricultural Chemical Safety Assessments
    • ADME Task Force, Technical Committee on Agricultural Chemical Safety Assessment, ILSI Health Sciences Institute, Washington, DC. November 2, 2004.
    • ILSI HESI (International Life Sciences Institute Health and Environmental Sciences Institute). 2004c. The Acquisition and Application of Absorption, Distribution, Metabolism, and Excretion (ADME) Data in Agricultural Chemical Safety Assessments. ADME Task Force, Technical Committee on Agricultural Chemical Safety Assessment, ILSI Health Sciences Institute, Washington, DC. November 2, 2004.
    • (2004)
  • 12
    • 20444422374 scopus 로고    scopus 로고
    • Neurotoxicity Risk Assessment for Human Health: Principles and Approaches
    • Environmental Health Criteria 223. Geneva: World Health Organization [online]. [accessed March 2, 2005].
    • IPCS (International Programme on Chemical Safety). 2001. Neurotoxicity Risk Assessment for Human Health: Principles and Approaches. Environmental Health Criteria 223. Geneva: World Health Organization [online]. Available: http://www.inchem.org/documents/ehc/ehc/ehc223.htm [accessed March 2, 2005].
    • (2001)
  • 13
    • 84988938853 scopus 로고    scopus 로고
    • The NTP Vision for the 21st Century
    • National Toxicology Program, National Institute for Environmental Health, Research Triangle Park, NC [online]. [accessed March 11, 2005].
    • NTP (National Toxicology Program). 2004. The NTP Vision for the 21st Century. National Toxicology Program, National Institute for Environmental Health, Research Triangle Park, NC [online]. Available: http://ntp-server.niehs.nih.gov/ntp/main_pages/NTPVision.pdf [accessed March 11, 2005].
    • (2004)
  • 14
    • 34248346118 scopus 로고    scopus 로고
    • Guideline Document for Neurotoxicity Testing
    • ENV/JM/MONO(2004) 25. OECD Series on Testing and Assessment No. 20. Organisation for Economic Cooperation and Development, Paris [online]. [accessed April 1, 2005].
    • OECD (Organisation for Economic Cooperation and Development). 2004. Guideline Document for Neurotoxicity Testing. ENV/JM/MONO(2004) 25. OECD Series on Testing and Assessment No. 20. Organisation for Economic Cooperation and Development, Paris [online]. Available: http://appli1.oecd.org/olis/2004doc.nsf/linkto/env-jm-mono(2004)25 [accessed April 1, 2005].
    • (2004)
  • 15
    • 84988965455 scopus 로고    scopus 로고
    • Draft ADME White Paper: The Acquisition and Application of Absorption, Distribution, Metabolism, and Excretion (ADME) Data in Agricultural Chemical Safety Assessments
    • International Life Sciences Institute, Health and Environmental Sciences Institute, Washington, DC.[online]. [accessed Nov. 16, 2005].
    • Barton, H., K. Baetcke, J.E. Chambers, J. Diliberto, N.G. Doerrer, J.H. Driver, C.H. Hastings, S. Iyengar, R. Krieger, T. Pastoor, B. Stahl, and C. Timchalk. 2005. Draft ADME White Paper: The Acquisition and Application of Absorption, Distribution, Metabolism, and Excretion (ADME) Data in Agricultural Chemical Safety Assessments. International Life Sciences Institute, Health and Environmental Sciences Institute, Washington, DC. 65 pp [online]. Available: http://www.hesiglobal.org/NR/rdonlyres/E53BA06D-2E40-43A3-9845-2A8218DDE7D3/0/ADMEDraft PaperJan05.pdf [accessed Nov. 16, 2005].
    • (2005) , pp. 65
    • Barton, H.1    Baetcke, K.2    Chambers, J.E.3    Diliberto, J.4    Doerrer, N.G.5    Driver, J.H.6    Hastings, C.H.7    Iyengar, S.8    Krieger, R.9    Pastoor, T.10    Stahl, B.11    Timchalk, C.12
  • 16
    • 0038278508 scopus 로고    scopus 로고
    • An update on in vitro test methods in human hepatic drug biotransformation research: Pros and cons
    • Brandon, E.F., C.D. Raap, I. Meijerman, J.H. Beijnen, and J.H. Schellens. 2003. An update on in vitro test methods in human hepatic drug biotransformation research: Pros and cons. Toxicol. Appl. Pharmacol. 189(3):233-246.
    • (2003) Toxicol. Appl. Pharmacol. , vol.189 , Issue.3 , pp. 233-246
    • Brandon, E.F.1    Raap, C.D.2    Meijerman, I.3    Beijnen, J.H.4    Schellens, J.H.5
  • 18
    • 33747370594 scopus 로고    scopus 로고
    • Genetic toxicology
    • 4th Ed, A.W. Hayes, ed. Philadelphia, PA: Taylor and Francis.
    • Brusick, D. 2001. Genetic toxicology. Pp. 819-852 in Principals and Methods of Toxicology, 4th Ed, A.W. Hayes, ed. Philadelphia, PA: Taylor and Francis.
    • (2001) Principals and Methods of Toxicology , pp. 819-852
    • Brusick, D.1
  • 19
    • 0029100441 scopus 로고
    • Incorporating biological information in quantitative risk assessment: An example with methylene chloride
    • Clewell, III, H.J. 1995a. Incorporating biological information in quantitative risk assessment: An example with methylene chloride. Toxicology 102 (1-2):83-94.
    • (1995) Toxicology , vol.102 , Issue.1-2 , pp. 83-94
    • Clewell, H.J.1
  • 20
    • 0029089341 scopus 로고
    • The application of physiologically based pharmacokinetic modeling in human health risk assessment of hazardous substances
    • Clewell, III, H.J. 1995b. The application of physiologically based pharmacokinetic modeling in human health risk assessment of hazardous substances. Toxicol. Lett. 79(1-3):207-217.
    • (1995) Toxicol. Lett. , vol.79 , Issue.1-3 , pp. 207-217
    • Clewell, H.J.1
  • 21
    • 0018327785 scopus 로고
    • Validation and characterization of the L5178Y/TK+/- mouse lymphoma mutagen assay system
    • Clive, D., K.O. Johnson, J.F. Spector, A.G. Batson, and M.M. Brown. 1979. Validation and characterization of the L5178Y/TK+/- mouse lymphoma mutagen assay system. Mutat. Res. 59(1):61-108.
    • (1979) Mutat. Res. , vol.59 , Issue.1 , pp. 61-108
    • Clive, D.1    Johnson, K.O.2    Spector, J.F.3    Batson, A.G.4    Brown, M.M.5
  • 22
    • 0035173057 scopus 로고    scopus 로고
    • Alternative models for carcinogenicity testing
    • Cohen, S.M., D. Robinson, and J. MacDonald. 2001. Alternative models for carcinogenicity testing. Toxicol. Sci. 64(1):14-19.
    • (2001) Toxicol. Sci. , vol.64 , Issue.1 , pp. 14-19
    • Cohen, S.M.1    Robinson, D.2    MacDonald, J.3
  • 23
    • 0035052852 scopus 로고    scopus 로고
    • Methods to identify and characterize developmental neurotoxicity for human health risk assessment. I: Behavioral effects
    • Cory-Slechta, D.A., K.M. Crofton, J.A. Foran, J.F. Ross, L.P. Sheets, B. Weiss, and B. Mileson. 2001. Methods to identify and characterize developmental neurotoxicity for human health risk assessment. I: Behavioral effects. Environ. Health Perspect. 109(Suppl.1):79-91.
    • (2001) Environ. Health Perspect. , vol.109 , pp. 79-91
    • Cory-Slechta, D.A.1    Crofton, K.M.2    Foran, J.A.3    Ross, J.F.4    Sheets, L.P.5    Weiss, B.6    Mileson, B.7
  • 24
    • 0026096161 scopus 로고
    • A metabolically competent human cell line expressing five cDNAs encoding procarcinogen-activating enzymes: Application to mutagen testing
    • Crespi, C.L., F.J. Gonzalez, D.T. Steimel, T.R. Turner, H.V. Gelboin, B.W. Penman, and R. Langenbach. 1991. A metabolically competent human cell line expressing five cDNAs encoding procarcinogen-activating enzymes: Application to mutagen testing. Chem. Res. Toxicol. 4(5):566-572.
    • (1991) Chem. Res. Toxicol. , vol.4 , Issue.5 , pp. 566-572
    • Crespi, C.L.1    Gonzalez, F.J.2    Steimel, D.T.3    Turner, T.R.4    Gelboin, H.V.5    Penman, B.W.6    Langenbach, R.7
  • 25
    • 0001885499 scopus 로고
    • Assays for the detection of chemically- induced chromosome damage in cultured mammalian cells
    • S. Venitt, and J.M. Parry, eds. Oxford: IRL Press.
    • Dean, B.J., and N. Danford. 1984. Assays for the detection of chemically- induced chromosome damage in cultured mammalian cells. Pp. 187-232 in Mutagenicity Testing: A Practical Approach, S. Venitt, and J.M. Parry, eds. Oxford: IRL Press.
    • (1984) Mutagenicity Testing: A Practical Approach , pp. 187-232
    • Dean, B.J.1    Danford, N.2
  • 26
    • 0036216461 scopus 로고    scopus 로고
    • Precision-cut organ slices as a tool to study toxicity and metabolism of xenobiotics with special reference to non-hepatic tissues
    • de Kanter, R., M. Monshouwer, D.K. Meijer, and G.M. Groothuis. 2002. Precision-cut organ slices as a tool to study toxicity and metabolism of xenobiotics with special reference to non-hepatic tissues. Curr. Drug Metab. 3(1):39-59.
    • (2002) Curr. Drug Metab. , vol.3 , Issue.1 , pp. 39-59
    • de Kanter, R.1    Monshouwer, M.2    Meijer, D.K.3    Groothuis, G.M.4
  • 28
    • 84988936552 scopus 로고    scopus 로고
    • DTP Human Tumor Cell Line Screen
    • Screening, Developmental Therapeutics Program, National Cancer Institute [online]. [accessed March 18, 2005].
    • DTP (Developmental Therapeutics Program). 2005. DTP Human Tumor Cell Line Screen. Screening, Developmental Therapeutics Program, National Cancer Institute [online]. Available: http://www.dtp.nci.nih.gov/branches/btb/ivclsp.html [accessed March 18, 2005].
    • (2005)
  • 29
    • 84988979319 scopus 로고    scopus 로고
    • Scientifically Validated Methods
    • [online]. [accessed March 16, 2005].
    • ECVAM (European Centre for the Validation Alternative Methods). 2005. Scientifically Validated Methods [online]. Available: http://ecvam.jrc.cec.eu.int/index.htm [accessed March 16, 2005].
    • (2005)
  • 30
    • 0242269225 scopus 로고    scopus 로고
    • Microbial Pesticide Test Guidelines OPPTS 885.3000
    • Background-Mammalian Toxicity/ Pathogenicity/Infectivity. EPA 712-C-96-314. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. [accessed March 14, 2005].
    • EPA (U.S. Environmental Protection Agency). 1996. Microbial Pesticide Test Guidelines OPPTS 885.3000. Background-Mammalian Toxicity/ Pathogenicity/Infectivity. EPA 712-C-96-314. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. Available: http://www.epa.gov/opptsfrs/OPPTS_Harmonized/885_Microbial_Pesticide_Test_Guidelines/Series/885-3000.pdf [accessed March 14, 2005].
    • (1996)
  • 31
    • 0004592386 scopus 로고    scopus 로고
    • Health Effects Test Guidelines OPPTS 870.1000
    • Acute Toxicity Testing-Background. EPA 712-C-98-189. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. [accessed October 7, 2005].
    • EPA (U.S. Environmental Protection Agency). 1998a. Health Effects Test Guidelines OPPTS 870.1000. Acute Toxicity Testing-Background. EPA 712-C-98-189. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. Available: http://www.epa.gov/opptsfrs/OPPTS_Harmonized/870_Health_Effects_Test_Guidelines/Series/870-1000.pdf [accessed October 7, 2005].
    • (1998)
  • 32
    • 0004592386 scopus 로고    scopus 로고
    • Health Effects Test Guidelines OPPTS 870.1100. Acute Oral Toxicity
    • EPA 712-C-98-190. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. [accessed March 15, 2005].
    • EPA (U.S. Environmental Protection Agency). 1998b. Health Effects Test Guidelines OPPTS 870.1100. Acute Oral Toxicity. EPA 712-C-98-190. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. Available: http://www.epa.gov/opptsfrs/OPPTS_Harmonized/870_Health_Effects_Test_Guidelines/Series/870-1100.pdf [accessed March 15, 2005].
    • (1998)
  • 33
    • 0004592386 scopus 로고    scopus 로고
    • Health Effects Test Guidelines OPPTS 870.1200. Acute Dermal Toxicity
    • EPA 712-C-98- 192. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. [accessed October 7, 2005].
    • EPA (U.S. Environmental Protection Agency). 1998d. Health Effects Test Guidelines OPPTS 870.1200. Acute Dermal Toxicity. EPA 712-C-98- 192. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. Available: http://www.epa.gov/opptsfrs/OPPTS_Harmonized/870_Health_Effects_Test_Guidelines/Series/870-200.pdf [accessed October 7, 2005].
    • (1998)
  • 34
    • 0004592386 scopus 로고    scopus 로고
    • Health Effects Test Guidelines OPPTS 870.4100. Chronic Toxicity
    • EPA 712-C-98-210. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. [accessed March 15, 2005].
    • EPA (U.S. Environmental Protection Agency). 1998e. Health Effects Test Guidelines OPPTS 870.4100. Chronic Toxicity. EPA 712-C-98-210. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. Available: http://www.epa.gov/opptsfrs/OPPTS_Harmonized/870_Health_Effects_Test_Guidelines/Series/870-4100.pdf [accessed March 15, 2005].
    • (1998)
  • 35
    • 0004592386 scopus 로고    scopus 로고
    • Health Effects Test Guidelines OPPTS 870.4200. Carcinogenicity
    • EPA 712-C-98-211. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. [accessed March 15, 2005].
    • EPA (U.S. Environmental Protection Agency). 1998f. Health Effects Test Guidelines OPPTS 870.4200. Carcinogenicity. EPA 712-C-98-211. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. Available: http://www.epa.gov/opptsfrs/OPPTS_Harmonized/870_Health_Effects_Test_Guidelines/Series/870-4200.pdf [accessed March 15, 2005].
    • (1998)
  • 36
    • 0004592386 scopus 로고    scopus 로고
    • Health Effects Test Guidelines OPPTS 870.4300. Combined Chronic Toxicity/ Carcinogenicity
    • EPA 712-C-98-212. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. [accessed March 15, 2005].
    • EPA (U.S. Environmental Protection Agency). 1998g. Health Effects Test Guidelines OPPTS 870.4300. Combined Chronic Toxicity/ Carcinogenicity. EPA 712-C-98-212. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. Available: http://www.epa.gov/opptsfrs/OPPTS_Harmonized/870_Health_Effects_Test_Guidelines/Series/870-4300.pdf [accessed March 15, 2005].
    • (1998)
  • 37
    • 0004592386 scopus 로고    scopus 로고
    • Health Effects Test Guidelines OPPTS 870.3800. Reproduction and Fertility Effects
    • EPA 712-C-98-208. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. [accessed March 15, 2005].
    • EPA (U.S. Environmental Protection Agency). 1998h. Health Effects Test Guidelines OPPTS 870.3800. Reproduction and Fertility Effects. EPA 712-C-98-208. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. Available: http://www.epa.gov/opptsfrs/OPPTS_Harmonized/870_Health_Effects_Test_Guidelines/Series/870-3800.pdf [accessed March 15, 2005].
    • (1998)
  • 38
    • 0003672079 scopus 로고    scopus 로고
    • Guidelines for Neurotoxicity Assessment
    • EPA/630/R-95/001F. National Center for Environmental Assessment, U.S. Environmental Protection Agency, Washington, DC [online]. [accessed March 15, 2005].
    • EPA (U.S. Environmental Protection Agency). 1998i. Guidelines for Neurotoxicity Assessment. EPA/630/R-95/001F. National Center for Environmental Assessment, U.S. Environmental Protection Agency, Washington, DC [online]. Available: http://www.epa.gov/ncea/raf/pdfs/neurotox.pdf [accessed March 15, 2005].
    • (1998)
  • 39
    • 0004592386 scopus 로고    scopus 로고
    • Health Effects Test Guidelines OPPTS 870.3700
    • Prenatal Developmental Toxicity Study. EPA 712-C-98-207. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. [accessed March 15, 2005].
    • EPA (U.S. Environmental Protection Agency). 1998j. Health Effects Test Guidelines OPPTS 870.3700. Prenatal Developmental Toxicity Study. EPA 712-C-98-207. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. Available: http://www.epa.gov/opptsfrs/OPPTS_Harmonized/870_Health_Effects_Test_Guidelines/Series/870-3700.pdf [accessed March 15, 2005].
    • (1998)
  • 40
    • 0004592386 scopus 로고    scopus 로고
    • Health Effects Test Guidelines OPPTS 870.6200. Neurotoxicity Screening Battery
    • EPA 712-C-98-238. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. [accessed March 15, 2005].
    • EPA (U.S. Environmental Protection Agency). 1998k. Health Effects Test Guidelines OPPTS 870.6200. Neurotoxicity Screening Battery. EPA 712-C-98-238. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. Available: http://www.epa.gov/opptsfrs/OPPTS_Harmonized/870_Health_Effects_Test_Guidelines/Series/870-6200.pdf [accessed March 15, 2005].
    • (1998)
  • 41
    • 0004592386 scopus 로고    scopus 로고
    • Health Effects Test Guidelines OPPTS 870.6300. Developmental Neurotoxicity Study
    • EPA 712-C-98-239. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. [accessed March 15, 2005].
    • EPA (U.S. Environmental Protection Agency). 1998l. Health Effects Test Guidelines OPPTS 870.6300. Developmental Neurotoxicity Study. EPA 712-C-98-239. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. Available: http://www.epa.gov/opptsfrs/OPPTS_Harmonized/870_Health_Effects_Test_Guidelines/Series/870-6300.pdf [accessed March 15, 2005].
    • (1998)
  • 42
    • 0004592386 scopus 로고    scopus 로고
    • Health Effects Test Guidelines OPPTS 870.6100. Acute and 28-Day Delayed Neurotoxicity of Organophosphorus Substances
    • EPA 712-C-98-237. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. [accessed March 15, 2005].
    • EPA (U.S. Environmental Protection Agency). 1998m. Health Effects Test Guidelines OPPTS 870.6100. Acute and 28-Day Delayed Neurotoxicity of Organophosphorus Substances. EPA 712-C-98-237. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. Available: http://www.epa.gov/opptsfrs/OPPTS_Harmonized/870_Health_Effects_Test_Guidelines/Series/870-6100.pdf [accessed March 15, 2005].
    • (1998)
  • 43
    • 0004592386 scopus 로고    scopus 로고
    • Health Effects Test Guidelines OPPTS 870.6500. Schedule-Controlled Operant Behavior
    • EPA 712-C-98-240. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. [accessed March 15, 2005].
    • EPA (U.S. Environmental Protection Agency). 1998n. Health Effects Test Guidelines OPPTS 870.6500. Schedule-Controlled Operant Behavior. EPA 712-C-98-240. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. Available: http://www.epa.gov/opptsfrs/OPPTS_Harmonized/870_Health_Effects_Test_Guidelines/Series/870-6500.pdf [accessed March 15, 2005].
    • (1998)
  • 44
    • 0004592386 scopus 로고    scopus 로고
    • Health Effects Test Guidelines OPPTS 870.6850. Peripheral Nerve Function
    • EPA 712-C-98- 241. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. [accessed March 15, 2005].
    • EPA (U.S. Environmental Protection Agency). 1998o. Health Effects Test Guidelines OPPTS 870.6850. Peripheral Nerve Function. EPA 712-C-98- 241. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. Available: http://www.epa.gov/opptsfrs/OPPTS_Harmonized/870_Health_Effects_Test_Guidelines/Series/870-6850.pdf [accessed March 15, 2005].
    • (1998)
  • 45
    • 33644565067 scopus 로고    scopus 로고
    • Health Effects Test Guidelines OPPTS 870.6855. Neurophysiology: Sensory Evoked Potentials
    • EPA 712-C-98-242. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. [accessed March 15, 2005].
    • EPA (U.S. Environmental Protection Agency). 1998p. Health Effects Test Guidelines OPPTS 870.6855. Neurophysiology: Sensory Evoked Potentials. EPA 712-C-98-242. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. Available: http://www.epa.gov/opptsfrs/OPPTS_Harmonized/870_Health_Effects_Test_Guidelines/Series/870-6855.pdf [accessed March 15, 2005].
    • (1998)
  • 46
    • 0004592386 scopus 로고    scopus 로고
    • Health Effects Test Guidelines OPPTS 870.7800. Immunotoxicity
    • EPA 712-C-98-351. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. [accessed March 9, 2005].
    • EPA (U.S. Environmental Protection Agency). 1998q. Health Effects Test Guidelines OPPTS 870.7800. Immunotoxicity. EPA 712-C-98-351. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. Available: http://www.epa.gov/opptsfrs/OPPTS_Harmonized/870_Health_Effects_Test_Guidelines/Series/870-7800.pdf [accessed March 9, 2005].
    • (1998)
  • 47
    • 0004592386 scopus 로고    scopus 로고
    • Health Effects Test Guidelines OPPTS 870.5100. Bacterial Reverse Mutation Test
    • EPA 712-C-98-247. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. [accessed February 18, 2005].
    • EPA (U.S. Environmental Protection Agency). 1998r. Health Effects Test Guidelines OPPTS 870.5100. Bacterial Reverse Mutation Test. EPA 712-C-98-247. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. Available: http://www.epa.gov/opptsfrs/OPPTS_Harmonized/870_Health_Effects_Test_Guidelines/Series/870-5100.pdf [accessed February 18, 2005].
    • (1998)
  • 48
    • 84988956575 scopus 로고    scopus 로고
    • Health Effects Test Guidelines OPPTS 870.5300
    • EPA 712-C-98-221. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. [accessed February 18, 2005].
    • EPA (U.S. Environmental Protection Agency). 1998s. Health Effects Test Guidelines OPPTS 870.5300. In Vitro Mammalian Cell Gene Mutation Test. EPA 712-C-98-221. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. Available: http://www.epa.gov/opptsfrs/OPPTS_Harmonized/870_Health_Effects_Test_Guidelines/Series/870-5300.pdf [accessed February 18, 2005].
    • (1998) Vitro Mammalian Cell Gene Mutation Test
  • 49
    • 0004592386 scopus 로고    scopus 로고
    • Health Effects Test Guidelines OPPTS 870.5380. Mammalian Spermatogonial Chromosome Aberration Test
    • EPA 712-C-98-224. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. [accessed March 14, 2005].
    • EPA (U.S. Environmental Protection Agency). 1998t. Health Effects Test Guidelines OPPTS 870.5380. Mammalian Spermatogonial Chromosome Aberration Test. EPA 712-C-98-224. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. Available: http://www.epa.gov/opptsfrs/OPPTS_Harmonized/870_Health_Effects_Test_Guidelines/Series/870-5380.pdf [accessed March 14, 2005].
    • (1998)
  • 50
    • 0004592386 scopus 로고    scopus 로고
    • Health Effects Test Guidelines OPPTS 870.5385. Mammalian Bone Marrow Chromosome Aberration Test
    • EPA 712-C-98-225. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. [accessed February 18, 2005].
    • EPA (U.S. Environmental Protection Agency). 1998u. Health Effects Test Guidelines OPPTS 870.5385. Mammalian Bone Marrow Chromosome Aberration Test. EPA 712-C-98-225. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. Available: http://www.epa.gov/opptsfrs/OPPTS_Harmonized/870_Health_Effects_Test_Guidelines/Series/870-5385.pdf [accessed February 18, 2005].
    • (1998)
  • 51
    • 0004592386 scopus 로고    scopus 로고
    • Health Effects Test Guidelines OPPTS 870.5450. Rodent Dominant Lethal Assay
    • EPA 712- C-98-227. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. [accessed February 18, 2005].
    • EPA (U.S. Environmental Protection Agency). 1998v. Health Effects Test Guidelines OPPTS 870.5450. Rodent Dominant Lethal Assay. EPA 712- C-98-227. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. Available: http://www.epa.gov/opptsfrs/OPPTS_Harmonized/870_Health_Effects_Test_Guidelines/Series/870-5450.pdf [accessed February 18, 2005].
    • (1998)
  • 52
    • 0004592386 scopus 로고    scopus 로고
    • Health Effects Test Guidelines OPPTS 870.5460. Rodent Heritable Translocation Assays
    • EPA 712-C-98-228. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. [accessed February 18, 2005].
    • EPA (U.S. Environmental Protection Agency). 1998w. Health Effects Test Guidelines OPPTS 870.5460. Rodent Heritable Translocation Assays. EPA 712-C-98-228. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. Available: http://www.epa.gov/opptsfrs/OPPTS_Harmonized/870_Health_Effects_Test_Guidelines/Series/870-5460.pdf [accessed February 18, 2005].
    • (1998)
  • 53
    • 0004592386 scopus 로고    scopus 로고
    • Health Effects Test Guidelines OPPTS 870.5500. Bacterial DNA Damage or Repair Tests
    • EPA 712-C-98-229. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. [accessed February 18, 2005].
    • EPA (U.S. Environmental Protection Agency). 1998x. Health Effects Test Guidelines OPPTS 870.5500. Bacterial DNA Damage or Repair Tests. EPA 712-C-98-229. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. Available: http://www.epa.gov/opptsfrs/OPPTS_Harmonized/870_Health_Effects_Test_Guidelines/Series/870-5500.pdf [accessed February 18, 2005].
    • (1998)
  • 54
    • 0004592386 scopus 로고    scopus 로고
    • Health Effects Test Guidelines OPPTS 870.7485. Metabolism and Pharmacokinetics
    • EPA 712-C-98-244. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. [accessed June 15, 2005].
    • EPA (U.S. Environmental Protection Agency). 1998y. Health Effects Test Guidelines OPPTS 870.7485. Metabolism and Pharmacokinetics. EPA 712-C-98-244. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. Available: http://www.epa.gov/opptsfrs/OPPTS_Harmonized/870_Health_Effects_Test_Guidelines/Series/870-7485.pdf [accessed June 15, 2005].
    • (1998)
  • 55
    • 1042299437 scopus 로고    scopus 로고
    • Toxicology Data Requirements for Assessing Risks of Pesticide Exposure to Children's Health
    • Draft Report of the Toxicology Working Group of the 10x Task Force, U.S. Environmental Protection Agency. April 28, 1999 [online]. [accessed October 24, 2005].
    • EPA (Environmental Protection Agency). 1999. Toxicology Data Requirements for Assessing Risks of Pesticide Exposure to Children's Health. Draft Report of the Toxicology Working Group of the 10x Task Force, U.S. Environmental Protection Agency. April 28, 1999 [online]. Available: http://www.epa.gov/scipoly/sap/1999/may/10xtx428.pdf [accessed October 24, 2005].
    • (1999)
  • 56
    • 13244271830 scopus 로고    scopus 로고
    • Health Effects Test Guidelines OPPTS 870.2600. Skin Sensitization
    • EPA 712-C-03-197. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. [accessed March 16, 2005].
    • EPA (U.S. Environmental Protection Agency). 2003. Health Effects Test Guidelines OPPTS 870.2600. Skin Sensitization. EPA 712-C-03-197. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. Available: http://iccvam.niehs.nih.gov/docs/EPA/870r_2600.pdf [accessed March 16, 2005].
    • (2003)
  • 57
    • 84988919309 scopus 로고    scopus 로고
    • Short-term tests for genetic toxicity
    • Section IV.C.1 in Redbook 2000, Toxicological Principles for the Safety Assessment of Food Ingredients, Office of Food Additive Safety, U.S. Food and Drug Administration [online]. [accessed March 14, 2005].
    • FDA (U.S. Food and Drug Administration). 2000a. Short-term tests for genetic toxicity. Section IV.C.1 in Redbook 2000, Toxicological Principles for the Safety Assessment of Food Ingredients, Office of Food Additive Safety, U.S. Food and Drug Administration [online]. Available: http:// www.cfsan.fda.gov/~redbook/red-ivc1.html [accessed March 14, 2005].
    • (2000)
  • 58
    • 84901655542 scopus 로고    scopus 로고
    • Mammalian erythrocyte micronucleus test
    • Section IV.C.1.d. in Redbook 2000, Toxicological Principles for the Safety Assessment of Food Ingredients, Office of Food Additive Safety, U.S. Food and Drug Administration [online]. [accessed February 18, 2005].
    • FDA (U.S. Food and Drug Administration). 2000b. Mammalian erythrocyte micronucleus test. Section IV.C.1.d. in Redbook 2000, Toxicological Principles for the Safety Assessment of Food Ingredients, Office of Food Additive Safety, U.S. Food and Drug Administration [online]. Available: http://www.cfsan.fda.gov/~redbook/redivc1d.html [accessed February 18, 2005].
    • (2000)
  • 59
    • 0038144117 scopus 로고    scopus 로고
    • Guidance for Industry: Immunotoxicology Evaluation of Investigational New Drugs
    • Center for Drug Evaluation and Research, Food and Drug Administration, U.S. Department of Health and Human Services [online]. [accessed March 16, 2005].
    • FDA (U.S. Food and Drug Administration). 2002. Guidance for Industry: Immunotoxicology Evaluation of Investigational New Drugs. Center for Drug Evaluation and Research, Food and Drug Administration, U.S. Department of Health and Human Services [online]. Available: http://www.fda.gov/cder/guidance/4945fnl.PDF [accessed March 16, 2005].
    • (2002)
  • 61
    • 0035044255 scopus 로고    scopus 로고
    • Methods to identify and characterize developmental neurotoxicity for human health risk assessment. II: Neuropathology
    • Environ. Health Perspect.
    • Garman, R.H., A.S. Fix, B.S. Jortner, K.F. Jensen, J.F. Hardisty, L. Claudio, and S. Ferenc. 2001. Methods to identify and characterize developmental neurotoxicity for human health risk assessment. II: Neuropathology. Environ. Health Perspect. 109(Suppl. 1):93-100.
    • (2001) , vol.109 , pp. 93-100
    • Garman, R.H.1    Fix, A.S.2    Jortner, B.S.3    Jensen, K.F.4    Hardisty, J.F.5    Claudio, L.6    Ferenc, S.7
  • 64
    • 0021845525 scopus 로고
    • Current status of bioassays in genetic toxicology-the dominant lethal assay
    • A report of the U.S. Enviromental Protection Agency Gene-Tox Program
    • Green, S., A. Auletta, J. Fabricant, R. Kapp, M. Manandhar, C.J. Sheu, J. Springer, and B. Whitfield. 1985. Current status of bioassays in genetic toxicology-the dominant lethal assay. A report of the U.S. Enviromental Protection Agency Gene-Tox Program. Mutat Res. 154(1):49-67.
    • (1985) Mutat Res. , vol.154 , Issue.1 , pp. 49-67
    • Green, S.1    Auletta, A.2    Fabricant, J.3    Kapp, R.4    Manandhar, M.5    Sheu, C.J.6    Springer, J.7    Whitfield, B.8
  • 66
    • 0031832805 scopus 로고    scopus 로고
    • Liver cell models in vitro toxicology
    • Guillouzo, A. 1998. Liver cell models in vitro toxicology. Environ. Health Perspect. 106(Suppl. 2):511-532.
    • (1998) Environ. Health Perspect. , vol.106 , pp. 511-532
    • Guillouzo, A.1
  • 67
    • 0034127726 scopus 로고    scopus 로고
    • In vivo rodent erythrocyte micronucleus assay. II. Some aspects of protocol design including repeated treatments, integration with toxicity testing, and automated scoring
    • Hayashi, M., J.T. MacGregor, D.G. Gatehouse, I.D. Adler, D.H. Blakey, S.D. Dertinger, G. Krishna, T. Morita, A. Russo, and S. Sutou. 2000. In vivo rodent erythrocyte micronucleus assay. II. Some aspects of protocol design including repeated treatments, integration with toxicity testing, and automated scoring. Environ. Mol. Mutagen. 35(3):234-252.
    • (2000) Environ. Mol. Mutagen. , vol.35 , Issue.3 , pp. 234-252
    • Hayashi, M.1    MacGregor, J.T.2    Gatehouse, D.G.3    Adler, I.D.4    Blakey, D.H.5    Dertinger, S.D.6    Krishna, G.7    Morita, T.8    Russo, A.9    Sutou, S.10
  • 68
    • 0035889630 scopus 로고    scopus 로고
    • Ciprofloxacin: In vivo genotoxicity studies
    • Herbold, B.A., S.Y. Brendler-Schwaab, and H.J. Ahr. 2001. Ciprofloxacin: In vivo genotoxicity studies. Mutat. Res. 498(1-2):193-205.
    • (2001) Mutat. Res. , vol.498 , Issue.1-2 , pp. 193-205
    • Herbold, B.A.1    Brendler-Schwaab, S.Y.2    Ahr, H.J.3
  • 69
    • 4243784858 scopus 로고    scopus 로고
    • Report of the International Workshop on In Vitro Methods for Assessing Acute Systematic Toxicity
    • NIH 04-4499. National Institutes of Health, U.S. Public Health Service, Department of Health and Human Services [online]. [accessed Dec. 7, 2005].
    • ICCVAM/NICEATM (Interagency Coordinating Committee on the Validation of Alternative Methods and National Toxicology Program Interagency Center for the Evaluation of Alternative Toxicological Methods). 2001. Report of the International Workshop on In Vitro Methods for Assessing Acute Systematic Toxicity. NIH 04-4499. National Institutes of Health, U.S. Public Health Service, Department of Health and Human Services [online]. Available: http://iccvam.niehs.nih.gov/methods/invidocs/finalall.pdf [accessed Dec. 7, 2005].
    • (2001)
  • 70
    • 0031217594 scopus 로고    scopus 로고
    • Mechanisms of fiber-induced genotoxicity
    • Jaurand, M.C. 1997. Mechanisms of fiber-induced genotoxicity. Environ. Health Perspect. 105(Suppl. 5):1073-1084.
    • (1997) Environ. Health Perspect. , vol.105 , pp. 1073-1084
    • Jaurand, M.C.1
  • 71
    • 0017647912 scopus 로고
    • A collaborative cytogenetics study to measure and minimize interlaboratory variation
    • Kilian, D.J., F.M. Moreland, M.C. Benge, M.S. Legator, and E.B. Whorton, Jr. 1977. A collaborative cytogenetics study to measure and minimize interlaboratory variation. Mutat Res. 44(1):97-104.
    • (1977) Mutat Res. , vol.44 , Issue.1 , pp. 97-104
    • Kilian, D.J.1    Moreland, F.M.2    Benge, M.C.3    Legator, M.S.4    Whorton, E.B.5
  • 72
    • 0019839464 scopus 로고
    • An evaluation of tests using DNA repair-deficient bacteria for predicting genotoxicity and carcinogenicity
    • A report of the U.S. EPA's Gene-Tox. Program
    • Leifer, Z., T. Kada, M. Mandel, E. Zeiger, R. Stafford, and H.S. Rosenkranz. 1981. An evaluation of tests using DNA repair-deficient bacteria for predicting genotoxicity and carcinogenicity. A report of the U.S. EPA's Gene-Tox. Program. Mutat. Res. 87(3):211-297.
    • (1981) Mutat. Res. , vol.87 , Issue.3 , pp. 211-297
    • Leifer, Z.1    Kada, T.2    Mandel, M.3    Zeiger, E.4    Stafford, R.5    Rosenkranz, H.S.6
  • 73
    • 0034676501 scopus 로고    scopus 로고
    • Precision-cut liver slices: Characteristics and use for in vitro pharmaco-toxicology
    • Lerche-Langrand, C., and H.J. Toutain. 2000. Precision-cut liver slices: Characteristics and use for in vitro pharmaco-toxicology. Toxicology 153(1- 3):221-253.
    • (2000) Toxicology , vol.153 , Issue.1-3 , pp. 221-253
    • Lerche-Langrand, C.1    Toutain, H.J.2
  • 74
    • 17044437803 scopus 로고    scopus 로고
    • Regulatory developmental neurotoxicology testing: Data evaluation for risk assessment purposes
    • Li, A.A. 2005. Regulatory developmental neurotoxicology testing: Data evaluation for risk assessment purposes. Environ. Toxicol. Pharmacol. 19(3):727-733.
    • (2005) Environ. Toxicol. Pharmacol. , vol.19 , Issue.3 , pp. 727-733
    • Li, A.A.1
  • 77
    • 0005431786 scopus 로고    scopus 로고
    • A Retrospective Analysis of Twelve Developmental Neurotoxicity Studies Submitted to the U.S. Environmental Protection Agency Office of Prevention, Pesticides and Toxic Substances (OPPTS)
    • Washington, DC. Draft Report, Nov.12, 1998 [online]. [accessed November 7, 2005].
    • Makris, S., K. Raffaelle, W. Sette, and J. Seed. 1998. A Retrospective Analysis of Twelve Developmental Neurotoxicity Studies Submitted to the U.S. Environmental Protection Agency Office of Prevention, Pesticides and Toxic Substances (OPPTS), Washington, DC. Draft Report, Nov.12, 1998 [online]. Available: http://www.epa.gov/scipoly/sap/1998/december/neuro.pdf [accessed November 7, 2005].
    • (1998)
    • Makris, S.1    Raffaelle, K.2    Sette, W.3    Seed, J.4
  • 78
    • 0020533372 scopus 로고
    • Revised methods for the Salmonella mutagenicity test
    • Maron, D.M., and B.N. Ames. 1983. Revised methods for the Salmonella mutagenicity test. Mutat Res. 113(3-4):173-215.
    • (1983) Mutat Res. , vol.113 , Issue.3-4 , pp. 173-215
    • Maron, D.M.1    Ames, B.N.2
  • 80
    • 0033673470 scopus 로고    scopus 로고
    • Cognitive evaluation: Is it needed in neurotoxicity screening? Symposium presented at the annual Behavioral Toxicology Society meeting, May 1999
    • Moser, V.C., S.E. Bowen, A.A. Li, W.S. Sette, and W.P. Weisenburger. 2000. Cognitive evaluation: Is it needed in neurotoxicity screening? Symposium presented at the annual Behavioral Toxicology Society meeting, May 1999. Neurotoxicol. Teratol. 22(6):785-798.
    • (2000) Neurotoxicol. Teratol. , vol.22 , Issue.6 , pp. 785-798
    • Moser, V.C.1    Bowen, S.E.2    Li, A.A.3    Sette, W.S.4    Weisenburger, W.P.5
  • 81
    • 0004178356 scopus 로고
    • Environmental Neurotoxicology
    • Washington, DC: National Academy Press.
    • NRC (National Research Council). 1992. Environmental Neurotoxicology. Washington, DC: National Academy Press.
    • (1992)
  • 82
    • 0004063705 scopus 로고    scopus 로고
    • The Murine Local Lymph Node Assay: A Test Method for Assessing the Allergic Contact Dermatitis Potential of Chemicals/Compounds
    • NIH Publication No. 99-4494. National Toxicology Program, Research Triangle Park, NC. February 1999 [online]. [accessed March 16, 2005].
    • NTP (National Toxicology Program). 1999. The Murine Local Lymph Node Assay: A Test Method for Assessing the Allergic Contact Dermatitis Potential of Chemicals/Compounds. NIH Publication No. 99-4494. National Toxicology Program, Research Triangle Park, NC. February 1999 [online]. Available: http://iccvam.niehs.nih.gov/methods/llnadocs/llnarep.pdf [accessed March 16, 2005].
    • (1999)
  • 83
    • 4243829818 scopus 로고
    • Acute Inhalation Toxicity
    • Chemicals Testing Guidelines No. 403. Paris: Organisation for Economic Cooperation and Development. May 12, 1981.
    • OECD (Organisation for Economic Cooperation and Development). 1981. Acute Inhalation Toxicity. Chemicals Testing Guidelines No. 403. Paris: Organisation for Economic Cooperation and Development. May 12, 1981.
    • (1981)
  • 84
    • 84874596122 scopus 로고
    • One-Generation Reproduction Toxicity Study
    • Chemicals Testing Guidelines No. 415. Paris: Organisation for Economic Cooperation and Development. May 26, 1983.
    • OECD (Organisation for Economic Cooperation and Development). 1983. One-Generation Reproduction Toxicity Study. Chemicals Testing Guidelines No. 415. Paris: Organisation for Economic Cooperation and Development. May 26, 1983.
    • (1983)
  • 85
    • 84871008062 scopus 로고    scopus 로고
    • Acute Dermal Toxicity
    • Chemicals Testing Guidelines No. 402. Paris: Organisation for Economic Cooperation and Development. February 24, 1987.
    • OECD (Organisation for Economic Cooperation and Development). 1987. Acute Dermal Toxicity. Chemicals Testing Guidelines No. 402. Paris: Organisation for Economic Cooperation and Development. February 24, 1987.
    • (1987)
  • 86
    • 84871902467 scopus 로고
    • Reproduction/Developmental Toxicity Screening Test
    • Chemicals Testing Guidelines No. 421. Paris: Organisation for Economic Cooperation and Development. July 27, 1995.
    • OECD (Organisation for Economic Cooperation and Development). 1995a. Reproduction/Developmental Toxicity Screening Test. Chemicals Testing Guidelines No. 421. Paris: Organisation for Economic Cooperation and Development. July 27, 1995.
    • (1995)
  • 87
    • 84875594981 scopus 로고
    • Repeated Dose 28-Day Oral Toxicity Study in Rodents
    • Chemicals Testing Guidelines No. 407. Paris: Organisation for Economic Cooperation and Development. July 27, 1995.
    • OECD (Organisation for Economic Cooperation and Development). 1995b. Repeated Dose 28-Day Oral Toxicity Study in Rodents. Chemicals Testing Guidelines No. 407. Paris: Organisation for Economic Cooperation and Development. July 27, 1995.
    • (1995)
  • 88
    • 84871917760 scopus 로고    scopus 로고
    • Combined Repeated Dose Toxicity Study With the Reproduction/ Developmental Toxicity Screening Test
    • Chemicals Testing Guidelines No. 422. Paris: Organisation for Economic Cooperation and Development. March 22, 1996.
    • OECD (Organisation for Economic Cooperation and Development). 1996. Combined Repeated Dose Toxicity Study With the Reproduction/ Developmental Toxicity Screening Test. Chemicals Testing Guidelines No. 422. Paris: Organisation for Economic Cooperation and Development. March 22, 1996.
    • (1996)
  • 89
    • 84874768462 scopus 로고    scopus 로고
    • Neurotoxicity Study in Rodents
    • Chemicals Testing Guidelines No. 424. Paris: Organisation for Economic Cooperation and Development. July 21, 1997.
    • OECD (Organisation for Economic Cooperation and Development). 1997. Neurotoxicity Study in Rodents. Chemicals Testing Guidelines No. 424. Paris: Organisation for Economic Cooperation and Development. July 21, 1997.
    • (1997)
  • 90
    • 0003521879 scopus 로고    scopus 로고
    • Repeated Dose 90-Day Oral Toxicity Study in Rodents
    • Chemicals Testing Guidelines No. 408. Paris: Organisation for Economic Cooperation and Development September 21, 1998.
    • OECD (Organisation for Economic Cooperation and Development). 1998. Repeated Dose 90-Day Oral Toxicity Study in Rodents. Chemicals Testing Guidelines No. 408. Paris: Organisation for Economic Cooperation and Development September 21, 1998.
    • (1998)
  • 91
    • 0003503757 scopus 로고    scopus 로고
    • Harmonized Integrated Classification System for Human Health and Environmental Hazards of Chemical Substances and Mixtures
    • ENV/JM/ MONO(2001)6. OECD Series on Testing and Assessment No. 33. Organisation for Economic Cooperation and Development [online]. [accessed March 14, 2005].
    • OECD (Organisation for Economic Cooperation and Development). 2001a. Harmonized Integrated Classification System for Human Health and Environmental Hazards of Chemical Substances and Mixtures. ENV/JM/ MONO(2001)6. OECD Series on Testing and Assessment No. 33. Organisation for Economic Cooperation and Development [online]. Available: http://iccvam.niehs.nih.gov/docs/OECD/hclfinaw.pdf [accessed March 14, 2005].
    • (2001)
  • 92
    • 84988960844 scopus 로고    scopus 로고
    • Prenatal Developmental Study
    • Chemicals Testing Guidelines No. 414. Paris: Organisation for Economic Cooperation and Development. January 22, 2001.
    • OECD (Organisation for Economic Cooperation and Development). 2001b. Prenatal Developmental Study. Chemicals Testing Guidelines No. 414. Paris: Organisation for Economic Cooperation and Development. January 22, 2001.
    • (2001)
  • 93
    • 0041684349 scopus 로고    scopus 로고
    • Two-Generation Reproduction Toxicity Study
    • Chemicals Testing Guidelines No. 416. Paris: Organisation for Economic Cooperation and Development. January 22, 2001.
    • OECD (Organisation for Economic Cooperation and Development). 2001c. Two-Generation Reproduction Toxicity Study. Chemicals Testing Guidelines No. 416. Paris: Organisation for Economic Cooperation and Development. January 22, 2001.
    • (2001)
  • 94
    • 84988959857 scopus 로고    scopus 로고
    • Acute Oral Toxicity-Fixed Dose Method
    • Chemicals Testing Guidelines No. 420. Paris: Organisation for Economic Cooperation and Development. December 20, 2001.
    • OECD (Organisation for Economic Cooperation and Development). 2001d. Acute Oral Toxicity-Fixed Dose Method. Chemicals Testing Guidelines No. 420. Paris: Organisation for Economic Cooperation and Development. December 20, 2001.
    • (2001)
  • 95
    • 33745758122 scopus 로고    scopus 로고
    • Acute Oral Toxicity-Acute Toxic Class Method
    • Chemicals Testing Guidelines No. 423. Paris: Organisation for Economic Cooperation and Development. December 20, 2001.
    • OECD (Organisation for Economic Cooperation and Development). 2001e. Acute Oral Toxicity-Acute Toxic Class Method. Chemicals Testing Guidelines No. 423. Paris: Organisation for Economic Cooperation and Development. December 20, 2001.
    • (2001)
  • 96
    • 33745758122 scopus 로고    scopus 로고
    • Acute Oral Toxicity: Up and Down Procedure
    • Chemicals Testing Guidelines No. 425. Paris: Organisation for Economic Cooperation and Development. December 20, 2001.
    • OECD (Organisation for Economic Cooperation and Development). 2001f. Acute Oral Toxicity: Up and Down Procedure. Chemicals Testing Guidelines No. 425. Paris: Organisation for Economic Cooperation and Development. December 20, 2001.
    • (2001)
  • 97
    • 0003488241 scopus 로고    scopus 로고
    • OECD Guidelines for the Testing of Chemicals, 15th Addendum
    • Paris: Organisation for Economic Cooperation and Development. April 2004.
    • OECD (Organisation for Economic Cooperation and Development). 2004a. OECD Guidelines for the Testing of Chemicals, 15th Addendum. Paris: Organisation for Economic Cooperation and Development. April 2004.
    • (2004)
  • 98
    • 84988982077 scopus 로고    scopus 로고
    • Draft Guidance Document on Reproductive Toxicity Testing and Assessment, Series on Testing and Assessment No.43.
    • Environment Directorate, Organisation for Economic Cooperation and Development, November 10, 2004 [online]. [accessed March 15, 2005].
    • OECD (Organisation for Economic Cooperation and Development). 2004b. Draft Guidance Document on Reproductive Toxicity Testing and Assessment, Series on Testing and Assessment No. 43. Environment Directorate, Organisation for Economic Cooperation and Development, November 10, 2004 [online]. Available: http://www.oecd.org/dataoecd/38/46/34030071.pdf [accessed March 15, 2005].
    • (2004)
  • 99
    • 34248346118 scopus 로고    scopus 로고
    • Guidance Document for Neurotoxicity Testing
    • ENV/JM/MONO (2004)25. Series on Testing and Assessment No. 20. Environment Directorate, Organisation for Economic Cooperation and Development, November 24, 2004 [online]. 56f580058e823/$FILE/JT00174673.PDF [accessed Nov. 16, 2005].
    • OECD (Organisation for Economic Cooperation and Development). 2004c. Guidance Document for Neurotoxicity Testing. ENV/JM/MONO (2004)25. Series on Testing and Assessment No. 20. Environment Directorate, Organisation for Economic Cooperation and Development, November 24, 2004 [online]. Available: http://appli1.oecd.org/olis/2004doc.nsf/43bb6130e5e86e5fc12569fa005d004c/c631c2551f372e47c12 56f580058e823/$FILE/JT00174673.PDF [accessed Nov. 16, 2005].
    • (2004)
  • 100
    • 84886576172 scopus 로고    scopus 로고
    • In vitro 3T3 NRU phototoxicity test
    • Chemicals Testing Guidelines No. 432. Paris: Organisation for Economic Cooperation and Development.
    • OECD (Organisation for Economic Cooperation and Development). 2004d. In vitro 3T3 NRU phototoxicity test. Chemicals Testing Guidelines No. 432. Paris: Organisation for Economic Cooperation and Development.
    • (2004)
  • 101
    • 84960318222 scopus 로고    scopus 로고
    • In vitro skin corrosion: Human skin model test
    • Chemicals Testing Guidelines No. 431. Paris: Organisation for Economic Cooperation and Development.
    • OECD (Organisation for Economic Cooperation and Development). 2004e. In vitro skin corrosion: Human skin model test. Chemicals Testing Guidelines No. 431. Paris: Organisation for Economic Cooperation and Development.
    • (2004)
  • 102
    • 84882750443 scopus 로고    scopus 로고
    • In vitro skin corrosion: Transcutaneious electrical resistance test (TER)
    • Chemicals Testing Guidelines No. 430. Paris: Organisation for Economic Cooperation and Development. [accessed Dec. 7, 2005].
    • OECD (Organisation for Economic Cooperation and Development). 2004f. In vitro skin corrosion: Transcutaneious electrical resistance test (TER). Chemicals Testing Guidelines No. 430. Paris: Organisation for Economic Cooperation and Development. Available: http://www.oecd.org/dataoecd/63/23/32037794.pdf [accessed Dec. 7, 2005].
    • (2004)
  • 103
    • 84988969760 scopus 로고    scopus 로고
    • In vitro membrane barrier test method for skin corrosion
    • Draft guideline. Chemicals Testing Guidelines No. 435. Paris: Organisation for Economic Cooperation and Development [online]. [accessed Dec. 7, 2005].
    • OECD (Organisation for Economic Cooperation and Development). 2004g. In vitro membrane barrier test method for skin corrosion. Draft guideline. Chemicals Testing Guidelines No. 435. Paris: Organisation for Economic Cooperation and Development [online]. Available: http://www.oecd.org/dataoecd/63/23/32037794.pdf [accessed Dec. 7, 2005].
    • (2004)
  • 104
    • 84988915848 scopus 로고    scopus 로고
    • Chemicals Testing: OECD Guidelines for the Testing of Chemicals - Sections 4: Health Effects
    • [online].[accessed March 14, 2005].
    • OECD (Organisation for Economic Cooperation and Development). 2005. Chemicals Testing: OECD Guidelines for the Testing of Chemicals - Sections 4: Health Effects [online]. Available: http://www.oecd.org/document/55/0,2340,en_2649_34377_2349687_1_1_1_1,00.html [accessed March 14, 2005].
    • (2005)
  • 105
    • 0036853189 scopus 로고    scopus 로고
    • Skin constructs for replacement of skin tissues for in vitro testing
    • Ponec, M. 2002. Skin constructs for replacement of skin tissues for in vitro testing. Adv. Drug Deliv. Rev. 54(Suppl.1):S19-S30.
    • (2002) Adv. Drug Deliv. Rev. , vol.54 , pp. S19-S30
    • Ponec, M.1
  • 107
    • 45849116106 scopus 로고    scopus 로고
    • Motor activity in developmental neurotoxicity testing: A cross-laboratory comparison of control data
    • [598].
    • Raffaele, K.C., W.F. Sette, S.L. Makris, V.C. Moser, and K.M. Crofton. 2003. Motor activity in developmental neurotoxicity testing: A cross-laboratory comparison of control data. The Toxicologist 72(Suppl. 1):123[598].
    • (2003) The Toxicologist , vol.72 , pp. 123
    • Raffaele, K.C.1    Sette, W.F.2    Makris, S.L.3    Moser, V.C.4    Crofton, K.M.5
  • 108
    • 32844474265 scopus 로고    scopus 로고
    • Learning and memory tests in developmental neurotoxicity testing: A cross-laboratory comparison of control data
    • [1342].
    • Raffaele, K.C., M. Gilbert, K.M. Crofton, S.L. Makris, and W.F. Sette. 2004. Learning and memory tests in developmental neurotoxicity testing: A cross-laboratory comparison of control data. The Toxicologist 78(Suppl. 1):276[1342].
    • (2004) The Toxicologist , vol.78 , pp. 276
    • Raffaele, K.C.1    Gilbert, M.2    Crofton, K.M.3    Makris, S.L.4    Sette, W.F.5
  • 109
    • 0033911258 scopus 로고    scopus 로고
    • Critical periods of vulnerability for the developing nervous system: Evidence from humans and animal models
    • Rice, D.C., and S. Barone. 2000. Critical periods of vulnerability for the developing nervous system: Evidence from humans and animal models. Environ. Health Perspect. 108(Suppl. 3):511-533.
    • (2000) Environ. Health Perspect. , vol.108 , pp. 511-533
    • Rice, D.C.1    Barone, S.2
  • 110
    • 32844458244 scopus 로고    scopus 로고
    • Auditory startle reflex habituation in developmental neurotoxicity testing: A cross-laboratory comparison of control data
    • [1341].
    • Sette, W.F., K.M. Crofton, S.L. Makris, J. Doherty, and K.C. Raffaele. 2004. Auditory startle reflex habituation in developmental neurotoxicity testing: A cross-laboratory comparison of control data. The Toxicologist 78(Suppl. 1):275[1341].
    • (2004) The Toxicologist , vol.78 , pp. 275
    • Sette, W.F.1    Crofton, K.M.2    Makris, S.L.3    Doherty, J.4    Raffaele, K.C.5
  • 111
    • 0003445536 scopus 로고    scopus 로고
    • Environmental Health Committee 223: Neurotoxicity Risk Assessment for Human Health: Principles and Approaches
    • [online]. [accessed October 7, 2005].
    • WHO (World Health Organization). 2001. Environmental Health Committee 223: Neurotoxicity Risk Assessment for Human Health: Principles and Approaches [online]. Available: http://www.inchem.org/documents/ehc/ehc/ehc223.htm [accessed October 7, 2005].
    • (2001)
  • 112
    • 0017402672 scopus 로고
    • Detection of chemical carcinogens by unscheduled DNA synthesis in rat liver primary cell cultures
    • Williams, G.M. 1977. Detection of chemical carcinogens by unscheduled DNA synthesis in rat liver primary cell cultures. Cancer Res. 37(6):1845-1851.
    • (1977) Cancer Res. , vol.37 , Issue.6 , pp. 1845-1851
    • Williams, G.M.1
  • 113
    • 0032465960 scopus 로고    scopus 로고
    • Identification of rodent carcinogens and noncarcinogens using genetic toxicity tests: Premises, promises and performance
    • Zeiger, E. 1998. Identification of rodent carcinogens and noncarcinogens using genetic toxicity tests: Premises, promises and performance. Regul. Toxicol. Pharmacol. 28(2):85-95.
    • (1998) Regul. Toxicol. Pharmacol. , vol.28 , Issue.2 , pp. 85-95
    • Zeiger, E.1
  • 114
    • 0017889653 scopus 로고
    • Arsenic exposure and mortality: A case referent study from a Swedish copper smelter
    • Axelson, O., E. Dahlgren, C.D. Jansson, and S.O. Rehnlund. 1978. Arsenic exposure and mortality: A case referent study from a Swedish copper smelter. Br. J. Ind. Med. 35(1):8-15.
    • (1978) Br. J. Ind. Med. , vol.35 , Issue.1 , pp. 8-15
    • Axelson, O.1    Dahlgren, E.2    Jansson, C.D.3    Rehnlund, S.O.4
  • 117
    • 0030625965 scopus 로고    scopus 로고
    • Issues involving biomarkers in the study of the genetics of human cancer
    • P. Toniolo, P. Boffetta, D. Shuker, N. Rothman, B. Hulka, and N. Pearce, eds. IARC Science Publications No. 142. Lyon, France: IARC.
    • Caporaso, N., and A. Goldstein. 1997. Issues involving biomarkers in the study of the genetics of human cancer. Pp. 237-250 in Application of Biomarkers in Cancer Epidemiology, P. Toniolo, P. Boffetta, D. Shuker, N. Rothman, B. Hulka, and N. Pearce, eds. IARC Science Publications No. 142. Lyon, France: IARC.
    • (1997) Application of Biomarkers in Cancer Epidemiology , pp. 237-250
    • Caporaso, N.1    Goldstein, A.2
  • 118
    • 0003893348 scopus 로고    scopus 로고
    • National Report on Human Exposure to Environmental Chemicals
    • U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, Atlanta, GA [online]. [accessed March 25, 2005].
    • CDC (Centers for Disease Control and Prevention). 2001. National Report on Human Exposure to Environmental Chemicals. U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, Atlanta, GA [online]. Available: http://www.noharm.org/details.cfm?ID=745&type=document [accessed March 25, 2005].
    • (2001)
  • 119
    • 0013202598 scopus 로고    scopus 로고
    • Second National Report on Human Exposure to Environmental Chemicals
    • U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, Atlanta, GA [online]. [accessed October 25, 2005].
    • CDC (Centers for Disease Control and Prevention). 2003. Second National Report on Human Exposure to Environmental Chemicals. U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, Atlanta, GA [online]. Available: http://www.serafin.ch/toxicreport.pdf [accessed October 25, 2005].
    • (2003)
  • 120
    • 84988920875 scopus 로고    scopus 로고
    • Environmental Public Health Tracking Program: Closing America's Environmental Public Health Gap 2004
    • U.S. Department of Health and Human Services, Center for Disease Control and Prevention, National Center for Environmental Health, Atlanta, GA [online]. [accessed March 22, 2005].
    • CDC (Centers for Disease Control and Prevention). 2004. Environmental Public Health Tracking Program: Closing America's Environmental Public Health Gap 2004. U.S. Department of Health and Human Services, Center for Disease Control and Prevention, National Center for Environmental Health, Atlanta, GA [online]. Available: http://www.cdc.gov/nceh/tracking/aag04.htm [accessed March 22, 2005].
    • (2004)
  • 121
    • 27744543374 scopus 로고    scopus 로고
    • Third National Report on Human Exposure to Environmental Chemicals
    • U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, Atlanta, GA [online]. [accessed March 25, 2005].
    • CDC (Centers for Disease Control and Prevention). 2005. Third National Report on Human Exposure to Environmental Chemicals. U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, Atlanta, GA [online]. Available: http://www.cdc.gov/exposurereport/pdf/third_report_chemicals.pdf [accessed March 25, 2005].
    • (2005)
  • 122
    • 10944236158 scopus 로고    scopus 로고
    • Association of chromosomal alterations with arsenite-induced tumorigenicity of human HaCaT keratinocytes in nude mice
    • Chien, C.W., M.C. Chiang, I.C. Ho, and T.C. Lee. 2004. Association of chromosomal alterations with arsenite-induced tumorigenicity of human HaCaT keratinocytes in nude mice. Environ Health Perspect. 112(17):1704-1710.
    • (2004) Environ Health Perspect. , vol.112 , Issue.17 , pp. 1704-1710
    • Chien, C.W.1    Chiang, M.C.2    Ho, I.C.3    Lee, T.C.4
  • 123
    • 0142070763 scopus 로고    scopus 로고
    • Health and Air Quality: Interpreting Science for Decision Makers
    • Cohen, A.J., D. Krewski, J. Samet, and R. Willes, eds. 2003. Health and Air Quality: Interpreting Science for Decision Makers. J. Toxicol. Environ. Health A 66(16-19):1489-1903.
    • (2003) J. Toxicol. Environ. Health A , vol.66 , Issue.16-19 , pp. 1489-1903
    • Cohen, A.J.1    Krewski, D.2    Samet, J.3    Willes, R.4
  • 124
    • 0015962718 scopus 로고
    • Angiosarcoma of liver in the manufacture of polyvinyl chloride
    • Creech, J.L., and M.N. Johnson. 1974. Angiosarcoma of liver in the manufacture of polyvinyl chloride. J. Occup. Med. 16(3):150-151.
    • (1974) J. Occup. Med. , vol.16 , Issue.3 , pp. 150-151
    • Creech, J.L.1    Johnson, M.N.2
  • 125
    • 0034912967 scopus 로고    scopus 로고
    • Modeling lung cancer risk from diesel exhaust: Suitability of the railroad worker cohort for quantitative risk assessment
    • Crump, K. 2001. Modeling lung cancer risk from diesel exhaust: Suitability of the railroad worker cohort for quantitative risk assessment. Risk Anal. 21(1):19-23.
    • (2001) Risk Anal. , vol.21 , Issue.1 , pp. 19-23
    • Crump, K.1
  • 127
    • 84988952746 scopus 로고    scopus 로고
    • Guideline for Good Clinical Practice, ICH Topic E 6, Step 5, Consolidated Guideline 1.5.96
    • The European Agency for the Evaluation of Medicinal Products, London, UK [online]. [accessed March 25, 2005].
    • EMEA (European Agency for the Evaluation of Medicinal Products). 2002. Guideline for Good Clinical Practice, ICH Topic E 6, Step 5, Consolidated Guideline 1.5.96. The European Agency for the Evaluation of Medicinal Products, London, UK [online]. Available: http://www.emea.eu.int/pdfs/human/ich/013595en.pdf [accessed March 25, 2005].
    • (2002)
  • 128
    • 0020440835 scopus 로고
    • Cancer among workers exposed to arsenic and other substances in a copper smelter
    • Enterline, P.E., and G.M. Marsh. 1982. Cancer among workers exposed to arsenic and other substances in a copper smelter. Am. J. Epidemiol. 116(6): 895-911.
    • (1982) Am. J. Epidemiol. , vol.116 , Issue.6 , pp. 895-911
    • Enterline, P.E.1    Marsh, G.M.2
  • 129
    • 0003980475 scopus 로고
    • Health Assessment Document for Inorganic Arsenic
    • Final Report. EPA 600/8-83/021F. U.S. Environmental Protection Agency, Office of Research and Development, Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Research Triangle Park, NC.
    • EPA (U.S. Environmental Protection Agency). 1984. Health Assessment Document for Inorganic Arsenic. Final Report. EPA 600/8-83/021F. U.S. Environmental Protection Agency, Office of Research and Development, Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Research Triangle Park, NC.
    • (1984)
  • 130
    • 0003532676 scopus 로고    scopus 로고
    • Carcinogenic Effects of Benzene: An Update
    • EPA/600/P-97/001F. National Center for Environmental Assessment, Office of Research and Development, U.S. Environmental Protection Agency, Washington, DC [online]. [accessed March 24, 2005].
    • EPA (U.S. Environmental Protection Agency). 1998. Carcinogenic Effects of Benzene: An Update. EPA/600/P-97/001F. National Center for Environmental Assessment, Office of Research and Development, U.S. Environmental Protection Agency, Washington, DC [online]. Available: http:// www.epa.gov/ncea/pdfs/benzenef.pdf [accessed March 24, 2005].
    • (1998)
  • 131
    • 84988977704 scopus 로고    scopus 로고
    • Methylmercury Criteria Document: Fish Tissue Criterion for Methylmercury to Protect Human Health Document
    • EPA-823-R-01-001. Office of Water, U.S. Environmental Protection Agency, Washington, DC [online]. [accessed March 29, 2005].
    • EPA (U.S. Environmental Protection Agency). 2001. Methylmercury Criteria Document: Fish Tissue Criterion for Methylmercury to Protect Human Health Document. EPA-823-R-01-001. Office of Water, U.S. Environmental Protection Agency, Washington, DC [online]. Available: http://www.epa.gov/waterscience/criteria/methylmercury/document.html [accessed March 29, 2005].
    • (2001)
  • 132
    • 8844253591 scopus 로고    scopus 로고
    • Staff Paper Prepared for the U.S. Environmental Protection Agency by Members of the Risk Assessment Task Force. EPA/100/B-04/001. Office of the Science Advisor, U.S. Environmental Protection Agency, Washington, DC [online]. [accessed March 22, 2005].
    • EPA (Environmental Protection Agency). 2004. Pp. 72-82 in An Examination of EPA Risk Assessment Principles and Practice, Staff Paper Prepared for the U.S. Environmental Protection Agency by Members of the Risk Assessment Task Force. EPA/100/B-04/001. Office of the Science Advisor, U.S. Environmental Protection Agency, Washington, DC [online]. Available: http://www.epa.gov/OSA/ratf-final.pdf [accessed March 22, 2005].
    • (2004) An Examination of EPA Risk Assessment Principles and Practice , pp. 72-82
  • 133
    • 84988915912 scopus 로고    scopus 로고
    • Air Quality Criteria for Ozone and Related Photochemical Oxidants (First External Review Draft)
    • EPA/600/R-05/004aA-cA. National Center for Environmental Assessment, U.S. Environmental Protection Agency, Washington, DC [online]. [accessed March 29, 2005].
    • EPA (Environmental Protection Agency). 2005a. Air Quality Criteria for Ozone and Related Photochemical Oxidants (First External Review Draft). EPA/600/R-05/004aA-cA. National Center for Environmental Assessment, U.S. Environmental Protection Agency, Washington, DC [online]. Available: http://cfpub.epa.gov/ncea/cfm/recordisplay.cfm?deid=114523 [accessed March 29, 2005].
    • (2005)
  • 134
    • 25844488093 scopus 로고    scopus 로고
    • Review of the National Ambient Air Quality Standards for Particulate Matter: Policy Assessment of Scientific and Technical Information
    • OAQPS Staff Paper-Second Draft. January 2005 [online]. [accessed March 29, 2005].
    • EPA (Environmental Protection Agency). 2005b. Review of the National Ambient Air Quality Standards for Particulate Matter: Policy Assessment of Scientific and Technical Information. OAQPS Staff Paper-Second Draft. January 2005 [online]. Available: http://www.epa.gov/ttn/naaqs/standards/pm/data/pm_staff_paper_2nddraft.pdf [accessed March 29, 2005].
    • (2005)
  • 136
    • 84988983147 scopus 로고    scopus 로고
    • Natural Toxins: Aflatoxins
    • U.S. Food and Drug Administration, Center for Food Safety and Applied Nutrition [online]. [accessed March 29, 2005].
    • FDA (U.S. Food and Drug Administration). 2003. Natural Toxins: Aflatoxins. Foodborne Pathogenic Microorganisms and Natural Toxins Handbook: The Bud Bug Book. U.S. Food and Drug Administration, Center for Food Safety and Applied Nutrition [online]. Available: http://www.cfsan.fda. gov/~mow/chap41.html [accessed March 29, 2005].
    • (2003) Foodborne Pathogenic Microorganisms and Natural Toxins Handbook: The Bud Bug Book
  • 140
    • 84995067139 scopus 로고
    • The Future of Public Health
    • Washington, DC: National Academy Press.
    • IOM (Institute of Medicine). 1988. The Future of Public Health. Washington, DC: National Academy Press.
    • (1988)
  • 141
    • 0020890560 scopus 로고
    • Arsenic and respiratory cancer in man: Follow-up of an occupational study
    • W. Lederer, and R. Fensterheim, eds. New York: Van Nostrand Reinhold.
    • Lee-Feldstein, A. 1983. Arsenic and respiratory cancer in man: Follow-up of an occupational study. Pp. 245-254 in Arsenic: Industrial, Biomedical, and Environmental Perspectives, W. Lederer, and R. Fensterheim, eds. New York: Van Nostrand Reinhold.
    • (1983) Arsenic: Industrial, Biomedical, and Environmental Perspectives , pp. 245-254
    • Lee-Feldstein, A.1
  • 142
    • 0242456206 scopus 로고    scopus 로고
    • Association between gaseous ambient air pollutants and adverse pregnancy outcomes in Vancouver, Canada
    • Liu, S., D. Krewski, Y. Shi, Y. Chen, and R.T. Burnett. 2003. Association between gaseous ambient air pollutants and adverse pregnancy outcomes in Vancouver, Canada. Environ. Health Perspect. 111(14):1773-1778.
    • (2003) Environ. Health Perspect. , vol.111 , Issue.14 , pp. 1773-1778
    • Liu, S.1    Krewski, D.2    Shi, Y.3    Chen, Y.4    Burnett, R.T.5
  • 143
    • 0018599003 scopus 로고
    • Lung cancer among pesticide workers exposed to inorganic arsenicals
    • Mabuchi, K., A.M. Lilienfeld, and L. Snell. 1979. Lung cancer among pesticide workers exposed to inorganic arsenicals. Arch. Environ. Health 34(5):312-320.
    • (1979) Arch. Environ. Health , vol.34 , Issue.5 , pp. 312-320
    • Mabuchi, K.1    Lilienfeld, A.M.2    Snell, L.3
  • 144
    • 0019731087 scopus 로고
    • Carcino- genicity bioassays of vinyl chloride monomer: A model of risk assessment on an experimental basis
    • Maltoni, C., G. Lefemine, A. Ciliberti, G. Coti, and D. Carretti. 1981. Carcino- genicity bioassays of vinyl chloride monomer: A model of risk assessment on an experimental basis. Environ. Health Perspect. 41:3-29.
    • (1981) Environ. Health Perspect. , vol.41 , pp. 3-29
    • Maltoni, C.1    Lefemine, G.2    Ciliberti, A.3    Coti, G.4    Carretti, D.5
  • 145
    • 0002925873 scopus 로고
    • Consideration of chromium as an industrial carcinogen
    • October 27-31, 1975, Toronto, Ontario, Canada, T.C. Hutchinson, ed. Toronto: Institute for Environmental Studies.
    • Mancuso, T.F. 1975. Consideration of chromium as an industrial carcinogen. Pp. 343-356 in Proceedings of the International Conference on Heavy Metals in the Environment, October 27-31, 1975, Toronto, Ontario, Canada, T.C. Hutchinson, ed. Toronto: Institute for Environmental Studies.
    • (1975) Proceedings of the International Conference on Heavy Metals in the Environment , pp. 343-356
    • Mancuso, T.F.1
  • 146
    • 0031054426 scopus 로고    scopus 로고
    • Chromium as an industrial carcinogen: Part 1
    • Mancuso, T.F. 1997. Chromium as an industrial carcinogen: Part 1. Am. J. Ind. Med. 31(2):129-139.
    • (1997) Am. J. Ind. Med. , vol.31 , Issue.2 , pp. 129-139
    • Mancuso, T.F.1
  • 147
    • 76949122399 scopus 로고
    • Occupational cancer and other health hazards in a chromate plant: A medical appraisal. I. Lung cancers in chromate workers
    • Mancuso, T.F., and W.C. Hueper. 1951. Occupational cancer and other health hazards in a chromate plant: A medical appraisal. I. Lung cancers in chromate workers. Ind. Med. Surg. 20(8):358-363.
    • (1951) Ind. Med. Surg. , vol.20 , Issue.8 , pp. 358-363
    • Mancuso, T.F.1    Hueper, W.C.2
  • 151
    • 0033935775 scopus 로고    scopus 로고
    • Concentrations of organochlorines related to titers to Epstein-Barr virus early antigen IgG as risk factors for hairy cell leukemia
    • Nordstrom, M., L. Hardell, G. Lindstrom, H. Wingfors, K. Hardell, and A. Linde. 2000. Concentrations of organochlorines related to titers to Epstein-Barr virus early antigen IgG as risk factors for hairy cell leukemia. Environ. Health Perspect. 108(5):441-445.
    • (2000) Environ. Health Perspect. , vol.108 , Issue.5 , pp. 441-445
    • Nordstrom, M.1    Hardell, L.2    Lindstrom, G.3    Wingfors, H.4    Hardell, K.5    Linde, A.6
  • 152
    • 84964726994 scopus 로고    scopus 로고
    • Arsenic in Drinking Water
    • Washington, DC: National Academy Press.
    • NRC (National Research Council). 1999. Arsenic in Drinking Water. Washington, DC: National Academy Press.
    • (1999)
  • 153
    • 0004244049 scopus 로고    scopus 로고
    • Toxicological Effects of Methylmercury
    • Washington, DC: National Academy Press.
    • NRC (National Research Council). 2000. Toxicological Effects of Methylmercury. Washington, DC: National Academy Press.
    • (2000)
  • 154
    • 33646269860 scopus 로고    scopus 로고
    • Acute Exposure Guideline Levels for Selected Airborne Contaminants
    • Washington, DC: The National Academies Press.
    • NRC (National Research Council). 2004a. Acute Exposure Guideline Levels for Selected Airborne Contaminants, Vol. 4. Washington, DC: The National Academies Press.
    • (2004) , vol.4
  • 155
    • 11144226863 scopus 로고    scopus 로고
    • Research Priorities for Airborne Particulate Matter. IV. Continuing Research Progress
    • Washington, DC: The National Academies Press.
    • NRC (National Research Council). 2004b. Research Priorities for Airborne Particulate Matter. IV. Continuing Research Progress. Washington, DC: The National Academies Press.
    • (2004)
  • 156
    • 85032847739 scopus 로고    scopus 로고
    • Health Implications of Perchlorate Ingestion
    • Washington, DC: The National Academies Press.
    • NRC (National Research Council). 2005. Health Implications of Perchlorate Ingestion. Washington, DC: The National Academies Press.
    • (2005)
  • 157
    • 20744450891 scopus 로고    scopus 로고
    • Public Health Goal for Benzene in Drinking Water
    • Office of Environmental Health Hazard Assessment, California Environmental Protection Agency. June 2001 [online]. [accessed March 24, 2005].
    • OEHHA (Office of Environmental Health Hazard Assessment). 2001. Public Health Goal for Benzene in Drinking Water. Office of Environmental Health Hazard Assessment, California Environmental Protection Agency. June 2001 [online]. Available: http://www.oehha.ca.gov/water/phg/pdf/BenzeneFinPHG.pdf [accessed March 24, 2005].
    • (2001)
  • 158
    • 20744450891 scopus 로고    scopus 로고
    • Public Health Goal for Arsenic in Drinking Water
    • Office of Environmental Health Hazard Assessment, California Environmental Protection Agency. April 2004 [online]. [accessed March 24, 2005].
    • OEHHA (Office of Environmental Health Hazard Assessment). 2004a. Public Health Goal for Arsenic in Drinking Water. Office of Environmental Health Hazard Assessment, California Environmental Protection Agency. April 2004 [online]. Available: http://www.oehha.ca.gov/water/phg/pdf/asfinal.pdf [accessed March 24, 2005].
    • (2004)
  • 159
    • 20744450891 scopus 로고    scopus 로고
    • Public Health Goal for Perchlorate in Drinking Water
    • Office of Environmental Health Hazard Assessment, California Environmental Protection Agency. March 2004 [online]. [accessed March 24, 2005].
    • OEHHA (Office of Environmental Health Hazard Assessment). 2004b. Public Health Goal for Perchlorate in Drinking Water. Office of Environmental Health Hazard Assessment, California Environmental Protection Agency. March 2004 [online]. Available: http://www.oehha.ca.gov/water/phg/pdf/finalperchlorate31204.pdf [accessed March 24, 2005].
    • (2004)
  • 160
    • 84988920559 scopus 로고    scopus 로고
    • Recommendation for an Ambient Air Quality Standard for Ozone
    • Office of Environmental Health Hazard Assessment, California Environmental Protection Agency. June 2004 [online]. [accessed March 29, 2005].
    • OEHHA (Office of Environmental Health Hazard Assessment). 2004c. Recommendation for an Ambient Air Quality Standard for Ozone. Office of Environmental Health Hazard Assessment, California Environmental Protection Agency. June 2004 [online]. Available: http://www.oehha.ca.gov/air/criteria_pollutants/pdf/ozonerec1.pdf [accessed March 29, 2005].
    • (2004)
  • 161
    • 84988936693 scopus 로고    scopus 로고
    • Health Effects of Diesel Exhaust
    • Office of Environmental Health Hazard Assessment, California Environmental Protection Agency [online]. [accessed March 24, 2005].
    • OEHHA/ALA (Office of Environmental Health Hazard Assessment and American Lung Association of California). 2001. Health Effects of Diesel Exhaust. Office of Environmental Health Hazard Assessment, California Environmental Protection Agency [online]. Available: http://www.oehha.ca.gov/public_info/facts/pdf/diesel4-02.pdf [accessed March 24, 2005].
    • (2001)
  • 162
    • 0016203563 scopus 로고
    • Respiratory cancer and occupational exposure to arsenicals
    • Ott, M.G., B.B. Holder, and H.L. Gordon. 1974. Respiratory cancer and occupational exposure to arsenicals. Arch. Environ. Health. 29(5):250-255.
    • (1974) Arch. Environ. Health. , vol.29 , Issue.5 , pp. 250-255
    • Ott, M.G.1    Holder, B.B.2    Gordon, H.L.3
  • 163
    • 0036175013 scopus 로고    scopus 로고
    • Diesel exhaust and asthma: Hypotheses and molecular mechanisms of action
    • Pandya, R.J., G. Solomon, A. Kinner, and J.R. Balmes. 2002. Diesel exhaust and asthma: Hypotheses and molecular mechanisms of action. Environ. Health Perspect. 110(Suppl. 1):103-112.
    • (2002) Environ. Health Perspect. , vol.110 , pp. 103-112
    • Pandya, R.J.1    Solomon, G.2    Kinner, A.3    Balmes, J.R.4
  • 164
    • 0037803469 scopus 로고    scopus 로고
    • Serum 2,3,7,8- tetrachlorodibenzo-p-dioxin (TCDD) levels and thyroid function in Air Force veterans of the Vietnam War
    • Pavuk, M., A.J. Schecter, F.Z. Akhtar, and J.E. Michalek. 2003. Serum 2,3,7,8- tetrachlorodibenzo-p-dioxin (TCDD) levels and thyroid function in Air Force veterans of the Vietnam War. Ann. Epidemiol. 13(5):335-343.
    • (2003) Ann. Epidemiol. , vol.13 , Issue.5 , pp. 335-343
    • Pavuk, M.1    Schecter, A.J.2    Akhtar, F.Z.3    Michalek, J.E.4
  • 166
    • 16844384044 scopus 로고    scopus 로고
    • DNA damage from polycyclic aromatic hydrocarbons measured by benzo[a]pyrene-DNA adducts in mothers and newborns from Northern Manhattan, the World Trade Center Area, Poland, and China
    • Perera, F., D. Tang, R. Whyatt, S.A. Lederman, and W. Jedrychowski. 2005. DNA damage from polycyclic aromatic hydrocarbons measured by benzo[a]pyrene-DNA adducts in mothers and newborns from Northern Manhattan, the World Trade Center Area, Poland, and China. Cancer Epidemiol. Biomarkers Prev. 14(3):709-714.
    • (2005) Cancer Epidemiol. Biomarkers Prev. , vol.14 , Issue.3 , pp. 709-714
    • Perera, F.1    Tang, D.2    Whyatt, R.3    Lederman, S.A.4    Jedrychowski, W.5
  • 168
    • 0037029043 scopus 로고    scopus 로고
    • Lung cancer, cardiopulmonary mortality, and long- term exposure to fine particulate air pollution
    • Pope, C.A., III, R.T. Burnett, M.J. Thun, E.E. Calle, D. Krewski, K. Ito, and G.D. Thurston. 2002. Lung cancer, cardiopulmonary mortality, and long- term exposure to fine particulate air pollution. JAMA 287(9):1132-1141.
    • (2002) JAMA , vol.287 , Issue.9 , pp. 1132-1141
    • Pope, C.A.1    Burnett, R.T.2    Thun, M.J.3    Calle, E.E.4    Krewski, D.5    Ito, K.6    Thurston, G.D.7
  • 169
    • 0347086147 scopus 로고    scopus 로고
    • Cardiovascular mortality and long-term exposure to particulate air pollution: Epidemiological evidence of general pathophysiological pathways of disease
    • Pope, C.A., III, R.T. Burnett, G.D. Thurston, M.J. Thun, E.E. Calle, D. Krewski, and J.J. Godleski. 2003. Cardiovascular mortality and long-term exposure to particulate air pollution: Epidemiological evidence of general pathophysiological pathways of disease. Circulation 109(1):71-77.
    • (2003) Circulation , vol.109 , Issue.1 , pp. 71-77
    • Pope, C.A.1    Burnett, R.T.2    Thurston, G.D.3    Thun, M.J.4    Calle, E.E.5    Krewski, D.6    Godleski, J.J.7
  • 170
    • 0017760191 scopus 로고
    • A retrospective epidemiological study of mortality at a large western copper smelter
    • Rencher, A.C., M.W. Carter, and D.W. McKee. 1977. A retrospective epidemiological study of mortality at a large western copper smelter. J. Occup. Med. 19(11):754-758.
    • (1977) J. Occup. Med. , vol.19 , Issue.11 , pp. 754-758
    • Rencher, A.C.1    Carter, M.W.2    McKee, D.W.3
  • 173
    • 0344621312 scopus 로고
    • Bronchial cancer of arsenic-poisoned vintagers [in German]
    • Roth, F. 1958. Bronchial cancer of arsenic-poisoned vintagers [in German]. Virchows. Arch. 331(2):119-137.
    • (1958) Virchows. Arch. , vol.331 , Issue.2 , pp. 119-137
    • Roth, F.1
  • 174
    • 84988960747 scopus 로고    scopus 로고
    • Health effects associated with exposure to ambient air pollution
    • L. Craig, D. Krewski, J. Shortreed, and J. Samet, eds. Institute for Risk Research, University of Waterloo, Waterloo, Ontario [online]. [accessed Oct. 5, 2005].
    • Samet, J., and D. Krewski. 2005. Health effects associated with exposure to ambient air pollution. Pp. 55-76 in Strategies for Clean Air and Health, L. Craig, D. Krewski, J. Shortreed, and J. Samet, eds. Institute for Risk Research, University of Waterloo, Waterloo, Ontario [online]. Available: http://www.irr-neram.ca/rome/Proceedings/Samet.pdf [accessed Oct. 5, 2005].
    • (2005) Strategies for Clean Air and Health , pp. 55-76
    • Samet, J.1    Krewski, D.2
  • 175
    • 0034649702 scopus 로고    scopus 로고
    • Fine particulate air pollution and mortality in 20 U.S. cities, 1987-1994
    • Samet, J.M., F. Dominici, F.C. Curriero, I. Coursac, and S.L. Zeger. 2000. Fine particulate air pollution and mortality in 20 U.S. cities, 1987-1994. N. Engl. J. Med. 343(24):1742-1749.
    • (2000) N. Engl. J. Med. , vol.343 , Issue.24 , pp. 1742-1749
    • Samet, J.M.1    Dominici, F.2    Curriero, F.C.3    Coursac, I.4    Zeger, S.L.5
  • 176
    • 0242610784 scopus 로고    scopus 로고
    • p53 mutations in bladder cancer: Evidence for exogenous versus endogenous risk factors
    • Schroeder, J.C., K. Conway, Y. Li, K. Mistry, D.A. Bell, and J.A. Taylor. 2003. p53 mutations in bladder cancer: Evidence for exogenous versus endogenous risk factors. Cancer Res. 63(21):7530-7538.
    • (2003) Cancer Res. , vol.63 , Issue.21 , pp. 7530-7538
    • Schroeder, J.C.1    Conway, K.2    Li, Y.3    Mistry, K.4    Bell, D.A.5    Taylor, J.A.6
  • 177
    • 0024403940 scopus 로고
    • Effects of route of administration on tissue distribution of DNA adducts in mice: Comparison of 7H-dibenzo(c,g)carbazole, benzo(a)pyrene, and 2-acetylaminofluorene
    • Schurdak, M.E., and K. Randerath. 1989. Effects of route of administration on tissue distribution of DNA adducts in mice: Comparison of 7H-dibenzo(c,g)carbazole, benzo(a)pyrene, and 2-acetylaminofluorene. Cancer Res. 49(10):2633-2638.
    • (1989) Cancer Res. , vol.49 , Issue.10 , pp. 2633-2638
    • Schurdak, M.E.1    Randerath, K.2
  • 179
    • 1642579585 scopus 로고    scopus 로고
    • Darwin to DNA, molecules to morphology: The end of classical population genetics and the road ahead
    • Singh, R.S. 2003. Darwin to DNA, molecules to morphology: The end of classical population genetics and the road ahead. Genome 46(6):938-942.
    • (2003) Genome , vol.46 , Issue.6 , pp. 938-942
    • Singh, R.S.1
  • 180
    • 1542531912 scopus 로고    scopus 로고
    • Association between urinary 1-hydroxypyrene and genotoxic effects in coke oven workers
    • Siwinska, E., D. Mielzynska, and L. Kapka. 2004. Association between urinary 1-hydroxypyrene and genotoxic effects in coke oven workers. Occup. Environ. Med. 61(3):e10.
    • (2004) Occup. Environ. Med. , vol.61 , Issue.3
    • Siwinska, E.1    Mielzynska, D.2    Kapka, L.3
  • 181
    • 0021960023 scopus 로고
    • Mortality among a cohort of U.S. cadmium production workers: An update
    • Thun, M.J., T.M. Schnorr, A.B. Smith, and W.E. Halperin. 1985. Mortality among a cohort of U.S. cadmium production workers: An update. J. Natl. Cancer Inst. 74(2):325-333.
    • (1985) J. Natl. Cancer Inst. , vol.74 , Issue.2 , pp. 325-333
    • Thun, M.J.1    Schnorr, T.M.2    Smith, A.B.3    Halperin, W.E.4
  • 182
    • 0017113358 scopus 로고
    • A cohort study on mortality from cancer and other causes among workers at a metal refinery
    • Tokudome, S., and M. Kuratsune. 1976. A cohort study on mortality from cancer and other causes among workers at a metal refinery. Int. J. Cancer 17(3):310-317.
    • (1976) Int. J. Cancer , vol.17 , Issue.3 , pp. 310-317
    • Tokudome, S.1    Kuratsune, M.2
  • 184
    • 0000479076 scopus 로고
    • Survey of literature relating to infant methemoglobinemia due to nitrate-contaminated water
    • 2.
    • Walton, G. 1951. Survey of literature relating to infant methemoglobinemia due to nitrate-contaminated water. Am. J. Public Health 41(8:2):986-996.
    • (1951) Am. J. Public Health , vol.41 , Issue.8 , pp. 986-996
    • Walton, G.1
  • 186
    • 0042750839 scopus 로고    scopus 로고
    • Biomarkers in Risk Assessment: Validity and Validation
    • Environmental Health Criteria 222. Geneva: World Health Organization.
    • WHO (World Health Organization). 2001. Biomarkers in Risk Assessment: Validity and Validation. Environmental Health Criteria 222. Geneva: World Health Organization.
    • (2001)
  • 188
    • 0028786792 scopus 로고
    • Correlation of DNA adducts in blood mononuclear cells with tobacco carcinogen-induced damage in human lung
    • Wiencke, J.K., K.T. Kelsey, A. Varkonyi, K. Semey, J.C. Wain, E. Mark, and D.C. Christiani. 1995. Correlation of DNA adducts in blood mononuclear cells with tobacco carcinogen-induced damage in human lung. Cancer Res. 55(21):4910-4914.
    • (1995) Cancer Res. , vol.55 , Issue.21 , pp. 4910-4914
    • Wiencke, J.K.1    Kelsey, K.T.2    Varkonyi, A.3    Semey, K.4    Wain, J.C.5    Mark, E.6    Christiani, D.C.7
  • 189
    • 0027096046 scopus 로고
    • Risk assessment for aflatoxin B1: A modeling approach
    • Wu-Williams, A.H., L. Zeise, and D. Thomas. 1992. Risk assessment for aflatoxin B1: A modeling approach. Risk Anal. 12(4):559-567.
    • (1992) Risk Anal. , vol.12 , Issue.4 , pp. 559-567
    • Wu-Williams, A.H.1    Zeise, L.2    Thomas, D.3
  • 190
    • 9944239644 scopus 로고    scopus 로고
    • Technical Guidance Document on Risk Assessment in Support of Commission Directive 93/67/EEC on Risk Assessment for New Notified Substances
    • Commission Regulation (EC) No. 1488/94 on Risk Assessment for Existing Substances, and Directive 98/8/EC of the European Parliament and the Council Concerning the Placing of Biocidal Products on the Market, 2nd Ed. EUR 20418 EN/1. European Chemicals Bureau, Institute for Health and Consumer Protection, Ispra, Italy [online]. [accessed March 21, 2005].
    • EC (European Commission). 2003. Technical Guidance Document on Risk Assessment in Support of Commission Directive 93/67/EEC on Risk Assessment for New Notified Substances; Commission Regulation (EC) No. 1488/94 on Risk Assessment for Existing Substances, and Directive 98/8/EC of the European Parliament and the Council Concerning the Placing of Biocidal Products on the Market, 2nd Ed. EUR 20418 EN/1. European Chemicals Bureau, Institute for Health and Consumer Protection, Ispra, Italy [online]. Available: http://ecb.jrc.it/index.php?CONTENU=/Technical-Guidance-Document/ [accessed March 21, 2005].
    • (2003)
  • 191
    • 84988933893 scopus 로고    scopus 로고
    • Discussion of registration, field testing, and experimental use permits. III Toxicology requirements
    • (e). EPA 712-C-96- 280. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. [accessed March 21, 2005].
    • EPA (U.S. Environmental Protection Agency). 1996. Discussion of registration, field testing, and experimental use permits. III Toxicology requirements. P. 3(e) in Microbial Pesticide Test Guidelines, OPPTS 885.0001. Overview for Microbial Pest Control Agents. EPA 712-C-96- 280. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. Available: http://www.epa.gov/oppbppd1/biopesticides/regtools/guidelines/oppts_885_0001.htm#(e)%20Discussion%20of%20registration [accessed March 21, 2005].
    • (1996) Microbial Pesticide Test Guidelines, OPPTS 885.0001. Overview for Microbial Pest Control Agents , pp. 3
  • 193
    • 84988942913 scopus 로고    scopus 로고
    • Microbial Pesticide Test Guidelines OPPTS 885, Group C - Toxicology Test Guidelines
    • Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. [accessed March 21, 2005].
    • EPA (U.S. Environmental Protection Agency). 2004. Microbial Pesticide Test Guidelines OPPTS 885, Group C - Toxicology Test Guidelines. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. Available: http://www.epa.gov/oppbppd1/biopesticides/regtools/guidelines/microbial_gdlns.htm [accessed March 21, 2005].
    • (2004)
  • 194
    • 84988940762 scopus 로고    scopus 로고
    • Endocrine Disruptor Screening Program, Assay Development and Validation, Assay Status Table
    • Office of Science Coordination and Policy; Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. [accessed Sept. 20, 2005].
    • EPA (U.S. Environmental Protection Agency). 2005. Endocrine Disruptor Screening Program, Assay Development and Validation, Assay Status Table. Office of Science Coordination and Policy; Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. Available: http://www.epa.gov/scipoly/oscpendo/assayvalidation/status.htm [accessed Sept. 20, 2005].
    • (2005)
  • 195
    • 0003529383 scopus 로고
    • Draft toxicology principals for safety assessment of direct food additives and color additives used in food
    • "Redbook II." Center for Food Safety and Applied Nutrition, U.S. Food and Drug Administration, Washington, DC.
    • FDA (U.S. Food and Drug Administration). 1993. Draft toxicology principals for safety assessment of direct food additives and color additives used in food. "Redbook II." Center for Food Safety and Applied Nutrition, U.S. Food and Drug Administration, Washington, DC.
    • (1993)
  • 196
    • 84988918155 scopus 로고    scopus 로고
    • Toxicological Testing of Food Additives
    • Office of Premarket Approval, Center for Food Safety and Applied Nutrition, U.S. Food and Drug Administration [online]. [accessed March 21, 2005].
    • FDA (U.S. Food and Drug Administration). 1997. Toxicological Testing of Food Additives. Office of Premarket Approval, Center for Food Safety and Applied Nutrition, U.S. Food and Drug Administration [online]. Available: http://www.cfsan.fda.gov/~dms/opa-tg1.html [accessed March 21, 2005].
    • (1997)
  • 197
    • 84988928955 scopus 로고    scopus 로고
    • General guidelines for designing and conducting toxicity studies
    • Section IV. B.1. in Redbook 2000, Toxicological Principles for the Safety Assessment of Food Ingredients, Office of Food Additive Safety, U.S. Food and Drug Administration [online]. [accessed March 21, 2005].
    • FDA (U.S. Food and Drug Administration). 2003. General guidelines for designing and conducting toxicity studies. Section IV. B.1. in Redbook 2000, Toxicological Principles for the Safety Assessment of Food Ingredients, Office of Food Additive Safety, U.S. Food and Drug Administration [online]. Available: http://www.cfsan.fda.gov/~redbook/red-ivb1.html [accessed March 21, 2005].
    • (2003)
  • 198
    • 27744559796 scopus 로고    scopus 로고
    • Chemical Regulation: Options Exist to Improve EPA's Ability to Assess Health Risks and Manage its Chemical Review Program
    • GAO-05-458. U.S. Government Accounting Office, Washington, DC. June 2005 [online]. [accessed Oct. 24, 2005].
    • GAO (U.S. Government Accounting Office). 2005. Chemical Regulation: Options Exist to Improve EPA's Ability to Assess Health Risks and Manage its Chemical Review Program. GAO-05-458. U.S. Government Accounting Office, Washington, DC. June 2005 [online]. Available: http://www.gao.gov/new.items/d05458.pdf [accessed Oct. 24, 2005].
    • (2005)
  • 200
    • 84965701932 scopus 로고
    • Toxicity Testing: Strategies to Determine Needs and Priorities
    • Washington, DC: National Academy Press.
    • NRC (National Research Council). 1984. Toxicity Testing: Strategies to Determine Needs and Priorities. Washington, DC: National Academy Press.
    • (1984)
  • 201
    • 84967539788 scopus 로고    scopus 로고
    • Hormonally Active Agents in the Environment
    • Washington, DC: National Academy Press.
    • NRC (National Research Council). 1999. Hormonally Active Agents in the Environment. Washington, DC: National Academy Press.
    • (1999)
  • 202
    • 84967537993 scopus 로고    scopus 로고
    • Scientific Frontiers in Developmental Toxicology and Risk Assessment
    • Washington, DC: National Academy Press.
    • NRC (National Research Council). 2000. Scientific Frontiers in Developmental Toxicology and Risk Assessment. Washington, DC: National Academy Press.
    • (2000)
  • 203
    • 53849086628 scopus 로고    scopus 로고
    • Manual for Investigation of HPV Chemicals
    • Organisation for Economic Cooperation and Development [online]. [accessed Sept. 20, 2005].
    • OECD (Organisation for Economic Cooperation and Development). 2004a. Manual for Investigation of HPV Chemicals. Organisation for Economic Cooperation and Development [online]. Available: http://www.oecd.org/document/7/0,2340,en_2649_201185_1947463_1_1_1_1,00.html. [accessed Sept. 20, 2005].
    • (2004)
  • 204
    • 84988954564 scopus 로고    scopus 로고
    • Conceptual Framework for the Testing and Assessment of Endocrine Disrupting Chemicals
    • Prepared by the Secretariat of the Test Guidelines Programme, Based on the Agreement Reached at the 6th Meeting of the EDTA Task Force, 24 and 25 June 2002, Tokyo, Japan [online]. [accessed March 21, 2005].
    • OECD (Organisation for Economic Cooperation and Development). 2004b. Conceptual Framework for the Testing and Assessment of Endocrine Disrupting Chemicals. Prepared by the Secretariat of the Test Guidelines Programme, Based on the Agreement Reached at the 6th Meeting of the EDTA Task Force, 24 and 25 June 2002, Tokyo, Japan [online]. Available: http://www.oecd.org/dataoecd/17/33/23652447.doc [accessed March 21, 2005].
    • (2004)
  • 206
    • 0035684801 scopus 로고    scopus 로고
    • Toxic threats to neurologic development of children
    • Schettler T. 2001. Toxic threats to neurologic development of children. Environ. Health Perspect. 109(Suppl 6):813-816.
    • (2001) Environ. Health Perspect. , vol.109 , pp. 813-816
    • Schettler, T.1
  • 207
    • 33646705973 scopus 로고    scopus 로고
    • Globally Harmonized System of Classification and Labeling of Chemicals
    • United Nations Economic Commission for Europe [online]. [accessed Nov. 17, 2005].
    • UN (United Nations). 2003. Globally Harmonized System of Classification and Labeling of Chemicals. United Nations Economic Commission for Europe [online]. Available: http://www.unece.org/trans/danger/publi/ghs/ghs_rev00/00files_e.html [accessed Nov. 17, 2005].
    • (2003)
  • 208
    • 0029092057 scopus 로고
    • Modeling human interindividual variability in metabolism and risk: The example of 4-aminobiphenyl
    • Bois, F.Y., G. Krowech, and L. Zeise. 1995. Modeling human interindividual variability in metabolism and risk: The example of 4-aminobiphenyl. Risk Anal. 15(2):205-213.
    • (1995) Risk Anal. , vol.15 , Issue.2 , pp. 205-213
    • Bois, F.Y.1    Krowech, G.2    Zeise, L.3
  • 209
    • 0000841438 scopus 로고
    • Do thresholds exist for developmental toxicants? A review of the theoretical and experimental evidence
    • H. Kalter, ed. New York: Plenum Press.
    • Daston, G.P. 1993. Do thresholds exist for developmental toxicants? A review of the theoretical and experimental evidence. Pp. 169-197 in Issues and Reviews in Teratology, Vol. 6, H. Kalter, ed. New York: Plenum Press.
    • (1993) Issues and Reviews in Teratology , vol.6 , pp. 169-197
    • Daston, G.P.1
  • 210
    • 0001853113 scopus 로고
    • Methods for establishing oral reference doses (RfDs)
    • W. Mertz, C.O. Abernathy, and S.S. Olin, eds. Washington, DC: ILSI Press.
    • Dourson, M.L. 1994. Methods for establishing oral reference doses (RfDs). Pp. 51-61 in Risk Assessment of Essential Elements, W. Mertz, C.O. Abernathy, and S.S. Olin, eds. Washington, DC: ILSI Press.
    • (1994) Risk Assessment of Essential Elements , pp. 51-61
    • Dourson, M.L.1
  • 211
    • 0021054771 scopus 로고
    • Regulatory history and experimental support of uncertainty (safety) factors
    • Dourson, M.L., and J.F. Stara. 1983. Regulatory history and experimental support of uncertainty (safety) factors. Regul. Toxicol. Pharmacol. 3(3):224-238.
    • (1983) Regul. Toxicol. Pharmacol. , vol.3 , Issue.3 , pp. 224-238
    • Dourson, M.L.1    Stara, J.F.2
  • 212
    • 0003804803 scopus 로고
    • Guidelines for Carcinogen Risk Assessment
    • EPA/630/R-00/004. Risk Assessment Forum, U.S. Environmental Protection Agency, Washington, DC [online]. [accessed March 30, 2005].
    • EPA (U.S. Environmental Protection Agency). 1986. Guidelines for Carcinogen Risk Assessment. EPA/630/R-00/004. Risk Assessment Forum, U.S. Environmental Protection Agency, Washington, DC [online]. Available: http://www.epa.gov/ncea/raf/car2sab/guidelines_1986.pdf [accessed March 30, 2005].
    • (1986)
  • 213
    • 0342356615 scopus 로고
    • Guidelines for Developmental Toxicity Risk Assessment
    • EPA/600/FR-91/001. Risk Assessment Forum, U.S. Environmental Protection Agency, Washington, DC [online]. [accessed March 30, 2005].
    • EPA (U.S. Environmental Protection Agency). 1991. Guidelines for Developmental Toxicity Risk Assessment. EPA/600/FR-91/001. Risk Assessment Forum, U.S. Environmental Protection Agency, Washington, DC [online]. Available: http://www.epa.gov/ncea/raf/pdfs/devtox.pdf [accessed March 30, 2005].
    • (1991)
  • 214
    • 0003536223 scopus 로고
    • Methods for Derivation of Inhalation Reference Concentrations and Application of Inhalation Dosimetry
    • EPA/600/8-90/066F. Environmental Criteria and Assessment Office, Office of Health and Environmental Assessment, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, NC. October 1994.
    • EPA (U.S. Environmental Protection Agency). 1994. Methods for Derivation of Inhalation Reference Concentrations and Application of Inhalation Dosimetry. EPA/600/8-90/066F. Environmental Criteria and Assessment Office, Office of Health and Environmental Assessment, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, NC. October 1994.
    • (1994)
  • 215
    • 84988966733 scopus 로고
    • Guidelines for Neurotoxicity Risk Assessment
    • EPA/630/R-95/001F. Risk Assessment Forum, U.S. Environmental Protection Agency, Washington, DC [online]. [accessed March 30, 2005].
    • EPA (U.S. Environmental Protection Agency). 1995. Guidelines for Neurotoxicity Risk Assessment. EPA/630/R-95/001F. Risk Assessment Forum, U.S. Environmental Protection Agency, Washington, DC [online]. Available: www.epa.gov/ncea/raf/pdfs/neurotox.pdf [accessed March 30, 2005].
    • (1995)
  • 216
    • 0003753796 scopus 로고    scopus 로고
    • Guidelines for Reproductive Toxicity Risk Assessment
    • EPA/630/R-96/009. Risk Assessment Forum, U.S. Environmental Protection Agency, Washington, DC [online]. [accessed March 30, 2005].
    • EPA (U.S. Environmental Protection Agency). 1996a. Guidelines for Reproductive Toxicity Risk Assessment. EPA/630/R-96/009. Risk Assessment Forum, U.S. Environmental Protection Agency, Washington, DC [online]. Available: http://www.epa.gov/ncea/raf/pdfs/repro51.pdf [accessed March 30, 2005].
    • (1996)
  • 217
    • 0003672085 scopus 로고    scopus 로고
    • Proposed Guidelines for Carcinogen Risk Assessment
    • EPA/600/P-92/003C. Office of Research and Development, U.S. Environmental Protection Agency, Washington, DC [online]. [accessed April 4, 2005].
    • EPA (United States Environmental Protection Agency). 1996b. Proposed Guidelines for Carcinogen Risk Assessment. EPA/600/P-92/003C. Office of Research and Development, U.S. Environmental Protection Agency, Washington, DC [online]. Available: http://cfpub.epa.gov/ncea/raf/cra_prop.cfm [accessed April 4, 2005].
    • (1996)
  • 218
    • 0004592386 scopus 로고    scopus 로고
    • Health Effects Test Guidelines OPPTS 870.6300. Developmental Neurotoxicity Study
    • EPA 712-C-98-239. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. [accessed March 15, 2005].
    • EPA (U.S. Environmental Protection Agency). 1998. Health Effects Test Guidelines OPPTS 870.6300. Developmental Neurotoxicity Study. EPA 712-C-98-239. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. Available: http://www.epa.gov/opptsfrs/OPPTS_Harmonized/870_Health_Effects_Test_Guidelines/Series/870-6300.pdf [accessed March 15, 2005].
    • (1998)
  • 219
    • 0003662518 scopus 로고    scopus 로고
    • Guidelines for Carcinogen Risk Assessment
    • Review Draft NCEA-F-0644. Risk Assessment Forum, U.S. Environmental Protection Agency, Washington, DC [online]. [accessed March 30, 2005].
    • EPA (U.S. Environmental Protection Agency). 1999. Guidelines for Carcinogen Risk Assessment. Review Draft NCEA-F-0644. Risk Assessment Forum, U.S. Environmental Protection Agency, Washington, DC [online]. Available: http://www.epa.gov/ttn/atw/toxsource/carcinogens.html [accessed March 30, 2005].
    • (1999)
  • 220
    • 0141480662 scopus 로고    scopus 로고
    • A Review of the Reference Dose and Reference Concentration Processes
    • Final Report. EPA/ 630/P-02/002F. Risk Assessment Forum, U.S. Environmental Protection Agency, Washington, DC [online]. [accessed March 11, 2005].
    • EPA (U.S. Environmental Protection Agency). 2002a. A Review of the Reference Dose and Reference Concentration Processes. Final Report. EPA/ 630/P-02/002F. Risk Assessment Forum, U.S. Environmental Protection Agency, Washington, DC [online]. Available: http://www.epa.gov/iris/RFD_FINAL%5B1%5D.pdf [accessed March 11, 2005].
    • (2002)
  • 221
    • 0005487191 scopus 로고    scopus 로고
    • Determination of the Appropriate FQPA Safety Factor(s) in Tolerance Assessment
    • Office of Pesticide Programs, U.S. Environmental Protection Agency, Washington, DC. February 28, 2002 [online]. [accessed March 30, 2005].
    • EPA (U.S. Environmental Protection Agency). 2002b. Determination of the Appropriate FQPA Safety Factor(s) in Tolerance Assessment. Office of Pesticide Programs, U.S. Environmental Protection Agency, Washington, DC. February 28, 2002 [online]. Available: http://www.epa.gov/oppfead1/trac/science/determ.pdf [accessed March 30, 2005].
    • (2002)
  • 222
    • 84988950264 scopus 로고    scopus 로고
    • Risk Assessment for Non-cancer Effects
    • Air Toxics Website. U.S. Environmental Protection Agency [online]. [accessed April 1, 2005].
    • EPA (U.S. Environmental Protection Agency). 2004a. Risk Assessment for Non-cancer Effects. Air Toxics Website. U.S. Environmental Protection Agency [online]. Available: http://www.epa.gov/ttn/atw/toxsource/noncarcinogens.html [accessed April 1, 2005].
    • (2004)
  • 223
    • 8844253591 scopus 로고    scopus 로고
    • An Examination of EPA Risk Assessment Principles and Practice, Staff Paper Prepared for the U.S. Environmental Protection Agency by Members of the Risk Assessment Task Force
    • EPA/100/B-04/001. Office of the Science Advisor, U.S. Environmental Protection Agency, Washington, DC [online]. [accessed March 22, 2005].
    • EPA (U.S. Environmental Protection Agency). 2004b. An Examination of EPA Risk Assessment Principles and Practice, Staff Paper Prepared for the U.S. Environmental Protection Agency by Members of the Risk Assessment Task Force. EPA/100/B-04/001. Office of the Science Advisor, U.S. Environmental Protection Agency, Washington, DC [online]. Available: http://www.epa.gov/OSA/ratf-final.pdf [accessed March 22, 2005].
    • (2004)
  • 224
    • 30344443429 scopus 로고    scopus 로고
    • Guidelines for Carcinogen Risk Assessment
    • EPA/630/P-03/001B. Risk Assessment Forum, U.S. Environmental Protection Agency, Washington, DC. March 2005 [online]. [accessed Nov. 10, 2005].
    • EPA (U.S. Environmental Protection Agency). 2005a. Guidelines for Carcinogen Risk Assessment. EPA/630/P-03/001B. Risk Assessment Forum, U.S. Environmental Protection Agency, Washington, DC. March 2005 [online]. Available: http://www.epa.gov/iris/cancer032505.pdf [accessed Nov. 10, 2005].
    • (2005)
  • 225
    • 33645229436 scopus 로고    scopus 로고
    • Supplemental Guidance for Assessing Susceptibility for Early-Life Exposure to Carcinogens
    • EPA/630/R-03/003F. Risk Assessment Forum, U.S. Environmental Protection Agency, Washington, DC. March 2005 [online]. [accessed Nov. 10, 2005].
    • EPA (U.S. Environmental Protection Agency). 2005b. Supplemental Guidance for Assessing Susceptibility for Early-Life Exposure to Carcinogens. EPA/630/R-03/003F. Risk Assessment Forum, U.S. Environmental Protection Agency, Washington, DC. March 2005 [online]. Available: http://www.epa.gov/iris/children032505.pdf [accessed Nov. 10, 2005].
    • (2005)
  • 226
    • 84988944749 scopus 로고    scopus 로고
    • European Commission Directives: 67/548/EEC, updated 2001/59/EC
    • [online]. [accessed Nov. 10, 2005].
    • EU (European Union). 2001. European Commission Directives: 67/548/EEC, updated 2001/59/EC. Official Journal of European Communities 225:1-333 [online]. Available: http://europa.eu.int/eur-lex/pri/en/oj/dat/2001/l_225/l_22520010821en00010333.pdf [accessed Nov. 10, 2005].
    • (2001) Official Journal of European Communities , vol.225 , pp. 1-333
  • 227
    • 32144436237 scopus 로고    scopus 로고
    • Preamble to the IARC Monographs. 12. Evaluation
    • IARC Monographs Programme on the Evaluation of Carcinogenic Risk to Humans [online]. [accessed April 4, 2005].
    • IARC (International Agency for Research on Cancer). 1999. Preamble to the IARC Monographs. 12. Evaluation. IARC Monographs Programme on the Evaluation of Carcinogenic Risk to Humans [online]. Available: http://monographs.iarc.fr/monoeval/eval.html [accessed April 4, 2005].
    • (1999)
  • 228
    • 0003459737 scopus 로고    scopus 로고
    • IARC Monographs Programme on the Evaluation of Carcinogenic Risk to Humans
    • [online]. [accessed March 30, 2005].
    • IARC (International Agency for Research on Cancer). 2005a. IARC Monographs Programme on the Evaluation of Carcinogenic Risk to Humans [online]. Available: http://monographs.iarc.fr/ [accessed March 30, 2005].
    • (2005)
  • 229
    • 33845657685 scopus 로고    scopus 로고
    • DRAFT Preamble to the IARC Monographs
    • IARC Monographs on the Evaluation of Carcinogenic Risks to Humans. International Agency for Research on Cancer, World Health Organization, Lyon, France [online]. [accessed Oct. 28, 2005].
    • IARC (International Agency for Research on Cancer). 2005b. DRAFT Preamble to the IARC Monographs. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans. International Agency for Research on Cancer, World Health Organization, Lyon, France [online]. Available: http://monographs.iarc.fr/past&future/PreambleDraft2005.pdf. [accessed Oct. 28, 2005].
    • (2005)
  • 230
    • 30344450486 scopus 로고    scopus 로고
    • Gulf War and Health: Updated Literature Review of Sarin
    • Washington, DC: The National Academies Press.
    • IOM (Institute of Medicine). 2004. Gulf War and Health: Updated Literature Review of Sarin. Washington, DC: The National Academies Press.
    • (2004)
  • 231
    • 0003445521 scopus 로고
    • Assessing Human Health Risks of Chemicals: Derivation of Guidance Values for Health- Based Exposure Limits
    • Environmental Health Criteria 170. Geneva: World Health Organization [online]. [accessed March 31, 2005].
    • IPCS (International Programme on Chemical Safety). 1994. Assessing Human Health Risks of Chemicals: Derivation of Guidance Values for Health- Based Exposure Limits. Environmental Health Criteria 170. Geneva: World Health Organization [online]. Available: http://www.inchem.org/documents/ehc/ehc/ehc170.htm [accessed March 31, 2005].
    • (1994)
  • 232
    • 0004228114 scopus 로고    scopus 로고
    • Principles for the Assessment of Risk to Human Health from Exposure to Chemicals
    • Environmental Health Criteria 210. Geneva: World Health Organization [online]. [accessed March 30, 2005].
    • IPCS (International Programme on Chemical Safety). 1999. Principles for the Assessment of Risk to Human Health from Exposure to Chemicals. Environmental Health Criteria 210. Geneva: World Health Organization [online]. Available: http://www.inchem.org/documents/ehc/ehc/ehc210.htm [accessed March 30, 2005].
    • (1999)
  • 233
    • 0003457225 scopus 로고    scopus 로고
    • Guidance Document for the Use of Data in Development of Chemical-Specific Adjustment Factors (CSAFs) for Interspecies Differences and Human Variability in Dose/Concentration-Response Assessment
    • WHO/PCS/01.4. Geneva: World Health Organization. July 2001 [online]. [accessed March 31, 2005].
    • IPCS (International Programme on Chemical Safety). 2001. Guidance Document for the Use of Data in Development of Chemical-Specific Adjustment Factors (CSAFs) for Interspecies Differences and Human Variability in Dose/Concentration-Response Assessment. WHO/PCS/01.4. Geneva: World Health Organization. July 2001 [online]. Available: http://www.who.int/ipcs/publications/methods/harmonization/en/csafs_guidance:doc.pdf [accessed March 31, 2005].
    • (2001)
  • 235
    • 0003827385 scopus 로고
    • Of Acceptable Risk: Science and the Determination of Safety
    • Los Altos, CA: W. Kaufman.
    • Lowrence, W. 1976. Of Acceptable Risk: Science and the Determination of Safety. Los Altos, CA: W. Kaufman.
    • (1976)
    • Lowrence, W.1
  • 236
    • 0004113167 scopus 로고
    • Drinking Water and Health
    • Washington, DC: National Academy of Science.
    • NRC (National Research Council). 1977. Drinking Water and Health. Washington, DC: National Academy of Science.
    • (1977)
  • 237
    • 84966057454 scopus 로고
    • Risk Assessment in the Federal Government: Managing the Process
    • Washington, DC: National Academy Press.
    • NRC (National Research Council). 1983. Risk Assessment in the Federal Government: Managing the Process. Washington, DC: National Academy Press.
    • (1983)
  • 238
    • 0003655906 scopus 로고
    • Pesticides in the Diets of Infants and Children
    • Washington, DC: National Academy Press.
    • NRC (National Research Council). 1993. Pesticides in the Diets of Infants and Children. Washington, DC: National Academy Press.
    • (1993)
  • 239
    • 0004158548 scopus 로고
    • Science and Judgment in Risk Assessment
    • Washington, DC: National Academy Press.
    • NRC (National Research Council). 1994. Science and Judgment in Risk Assessment Washington, DC: National Academy Press.
    • (1994)
  • 240
    • 0011854685 scopus 로고    scopus 로고
    • Acute Exposure Guideline Levels for Selected Airborne Chemicals
    • Washington, DC: National Academy Press.
    • NRC (National Research Council). 2000. Acute Exposure Guideline Levels for Selected Airborne Chemicals, Vol. 1. Washington, DC: National Academy Press.
    • (2000) , vol.1
  • 241
    • 0004327386 scopus 로고    scopus 로고
    • Standing Operating Procedures for Developing Acute Exposure Guideline Levels for Hazardous Chemicals
    • Washington, DC: National Academy Press.
    • NRC (National Research Council). 2001. Standing Operating Procedures for Developing Acute Exposure Guideline Levels for Hazardous Chemicals. Washington, DC: National Academy Press.
    • (2001)
  • 242
    • 11144226863 scopus 로고    scopus 로고
    • Research Priorities for Airborne Particulate Matter. IV. Continuing Research Progress
    • Washington, DC: The National Academies Press.
    • NRC (National Research Council). 2004. Research Priorities for Airborne Particulate Matter. IV. Continuing Research Progress. Washington, DC: The National Academies Press.
    • (2004)
  • 243
    • 84988966093 scopus 로고    scopus 로고
    • Report on Carcinogens, 11th Ed, National Toxicology Program, Research Triangle Park, NC [online]. [accessed April 4, 2005].
    • NTP (National Toxicology Program). 2005. Report on Carcinogens, 11th Ed. National Toxicology Program, Research Triangle Park, NC [online]. Available: http://ntp.niehs.nih.gov/ntpweb/index.cfm?objectid=035E5806-F735-FE81-FF769DFE5509AF0A [accessed April 4, 2005].
    • (2005)
  • 244
    • 34248346118 scopus 로고    scopus 로고
    • Guideline Document for Neurotoxicity Testing
    • ENV/JM/MONO(2004) 25. OECD Series on Testing and Assessment No. 20. Organisation for Economic Cooperation and Development, Paris [online]. [accessed April 1, 2005].
    • OECD (Organisation for Economic Cooperation and Development). 2004. Guideline Document for Neurotoxicity Testing. ENV/JM/MONO(2004) 25. OECD Series on Testing and Assessment No. 20. Organisation for Economic Cooperation and Development, Paris [online]. Available: http://appli1.oecd.org/olis/2004doc.nsf/linkto/env-jm-mono(2004)25 [accessed April 1, 2005].
    • (2004)
  • 245
    • 0013114749 scopus 로고
    • Identifying and Regulating Carcinogens
    • OTA-BP-FI-42-P. Washington, DC: U.S. Government Printing Office.
    • OTA (Office of Technology and Assessment). 1987. Identifying and Regulating Carcinogens. OTA-BP-FI-42-P. Washington, DC: U.S. Government Printing Office.
    • (1987)
  • 246
    • 0033866724 scopus 로고    scopus 로고
    • The use of safety or uncertainty factors in the setting of acute reference doses
    • Renwick, AG. 2000. The use of safety or uncertainty factors in the setting of acute reference doses. Food Addit. Contam. 17(7):627-635.
    • (2000) Food Addit. Contam. , vol.17 , Issue.7 , pp. 627-635
    • Renwick, A.G.1
  • 247
    • 0031809917 scopus 로고    scopus 로고
    • Human variability and noncancer risk assessment-an analysis of the default uncertainty factor
    • Renwick, A.G., and N.R. Lazarus. 1998. Human variability and noncancer risk assessment-an analysis of the default uncertainty factor. Regul. Toxicol. Pharmacol. 27(1 Pt. 1):3-20.
    • (1998) Regul. Toxicol. Pharmacol. , vol.27 , Issue.1 , pp. 3-20
    • Renwick, A.G.1    Lazarus, N.R.2
  • 248
    • 9644258110 scopus 로고    scopus 로고
    • Globally Harmonized System of Classification and Labelling of Chemicals
    • United Nations Economic Commission for Europe [online]. [accessed April 1, 2005].
    • UN (United Nations). 2003. Globally Harmonized System of Classification and Labelling of Chemicals. United Nations Economic Commission for Europe [online]. Available: http://www.unece.org/trans/danger/publi/ghs/ghs_rev00/00files_e.html [accessed April 1, 2005].
    • (2003)
  • 251
    • 0004592386 scopus 로고    scopus 로고
    • Health Effects Test Guidelines OPPTS 870.1100. Acute Oral Toxicity
    • EPA 712-C-98- 190. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. [accessed March 15, 2005].
    • EPA (U.S. Environmental Protection Agency). 1998a. Health Effects Test Guidelines OPPTS 870.1100. Acute Oral Toxicity. EPA 712-C-98- 190. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. Available: http://www.epa.gov/opptsfrs/OPPTS_Harmonized/870_Health_Effects_Test_Guidelines/Series/870-1100.pdf [accessed March 15, 2005].
    • (1998)
  • 252
    • 0004592386 scopus 로고    scopus 로고
    • Health Effects Test Guidelines OPPTS 870.1200. Acute Dermal Toxicity
    • EPA 712-C-98- 192. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. [accessed Oct. 7, 2005].
    • EPA (U.S. Environmental Protection Agency). 1998b. Health Effects Test Guidelines OPPTS 870.1200. Acute Dermal Toxicity. EPA 712-C-98- 192. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. Available: http://www.epa.gov/opptsfrs/OPPTS_Harmonized/870_Health_Effects_Test_Guidelines/Series/870-1200.pdf [accessed Oct. 7, 2005].
    • (1998)
  • 253
    • 0004592386 scopus 로고    scopus 로고
    • Health Effects Test Guidelines OPPTS 870.1300. Acute Inhalation Toxicity
    • EPA-712-C- 98-193. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. [accessed Oct. 7, 2005].
    • EPA (U.S. Environmental Protection Agency). 1998c. Health Effects Test Guidelines OPPTS 870.1300. Acute Inhalation Toxicity. EPA-712-C- 98-193. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. Available: http://www.epa.gov/opptsfrs/OPPTS_Harmonized/870_Health_Effects_Test_Guidelines/Series/870-1300.pdf [accessed Oct. 7, 2005].
    • (1998)
  • 254
    • 0004592386 scopus 로고    scopus 로고
    • Health Effects Test Guidelines OPPTS 870.4300. Combined Chronic Toxicity/ Carcinogenicity
    • EPA 712-C-98-212. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. [accessed March 15, 2005].
    • EPA (U.S. Environmental Protection Agency). 1998d. Health Effects Test Guidelines OPPTS 870.4300. Combined Chronic Toxicity/ Carcinogenicity. EPA 712-C-98-212. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. Available: http://www.epa.gov/opptsfrs/OPPTS_Harmonized/870_Health_Effects_Test_Guidelines/Series/870-4300.pdf [accessed March 15, 2005].
    • (1998)
  • 255
    • 0004592386 scopus 로고    scopus 로고
    • Health Effects Test Guidelines OPPTS 870.3800. Reproduction and Fertility Effects
    • EPA 712-C-98-208. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. [accessed March 15, 2005].
    • EPA (U.S. Environmental Protection Agency). 1998e. Health Effects Test Guidelines OPPTS 870.3800. Reproduction and Fertility Effects. EPA 712-C-98-208. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. Available: http://www.epa.gov/opptsfrs/OPPTS_Harmonized/870_Health_Effects_Test_Guidelines/Series/870-3800.pdf [accessed March 15, 2005].
    • (1998)
  • 256
    • 0004592386 scopus 로고    scopus 로고
    • Health Effects Test Guidelines OPPTS 870.3100. 90-Day Oral Toxicity Study in Rodents
    • EPA 712-C-98-199. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. [accessed Oct. 26, 2005].
    • EPA (U.S. Environmental Protection Agency). 1998f. Health Effects Test Guidelines OPPTS 870.3100. 90-Day Oral Toxicity Study in Rodents. EPA 712-C-98-199. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. Available: http://www.epa.gov/docs/OPPTS_Harmonized/870_Health_Effects_Test_Guidelines/Series/870-3100.pdf [accessed Oct. 26, 2005].
    • (1998)
  • 257
    • 0004592386 scopus 로고    scopus 로고
    • Health Effects Test Guidelines OPPTS 870.2400. Acute Eye Irritation
    • EPA 712-C-98- 195. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. [accessed April 7, 2005].
    • EPA (U.S. Environmental Protection Agency). 1998g. Health Effects Test Guidelines OPPTS 870.2400. Acute Eye Irritation. EPA 712-C-98- 195. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. Available: http://www.epa.gov/opptsfrs/OPPTS_Harmonized/870_Health_Effects_Test_Guidelines/Series/870-2400.pdf [accessed April 7, 2005].
    • (1998)
  • 258
    • 0141480662 scopus 로고    scopus 로고
    • A Review of the Reference Dose and Reference Concentration Processes
    • Final Report. EPA/ 630/P-02/002F. Risk Assessment Forum, U.S. Environmental Protec-tion Agency, Washington, DC [online]. [accessed March 11, 2005].
    • EPA (U.S. Environmental Protection Agency). 2002. A Review of the Reference Dose and Reference Concentration Processes. Final Report. EPA/ 630/P-02/002F. Risk Assessment Forum, U.S. Environmental Protec-tion Agency, Washington, DC [online]. Available: http://www.epa.gov/iris/RFD_FINAL%5B1%5D.pdf [accessed March 11, 2005].
    • (2002)
  • 259
    • 84988950195 scopus 로고    scopus 로고
    • OPPTS Harmonized Test Guidelines
    • Series 870 Health Effects Test Guidelines-Final Guidelines. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. [accessed May 5, 2005].
    • EPA (U.S. Environmental Protection Agency). 2005. OPPTS Harmonized Test Guidelines. Series 870 Health Effects Test Guidelines-Final Guidelines. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. Available: http://www.epa.gov/opptsfrs/OPPTS_Harmonized/870_Health_Effects_Test_Guidelines/Series/ [accessed May 5, 2005].
    • (2005)
  • 260
    • 84926199387 scopus 로고    scopus 로고
    • The REACH Proposal Process Description
    • REACH (Registration, Evaluation and Authorisation of Chemicals), Enterprise and Industry, European Union [online]. [accessed March 8, 2005].
    • EU (European Union). 2004. The REACH Proposal Process Description. REACH (Registration, Evaluation and Authorisation of Chemicals), Enterprise and Industry, European Union [online]. Available: http://europa.eu.int/comm/enterprise/reach/docs/reach/reach_process_description-2004_06_15.pdf [accessed March 8, 2005].
    • (2004)
  • 261
    • 0004303665 scopus 로고
    • Report of the NTP Ad Hoc Panel on Chemical Carcinogenesis and Testing Evaluation
    • NTP Board of Scientific Counselors, U.S. Department of Health and Human Services. August 17, 1984 [online]. [accessed Oct. 26, 2005].
    • NTP (National Toxicology Program). 1984. Report of the NTP Ad Hoc Panel on Chemical Carcinogenesis and Testing Evaluation. NTP Board of Scientific Counselors, U.S. Department of Health and Human Services. August 17, 1984 [online]. Available: http://ntp-server.niehs.nih.gov/files/NTPAdHocPanel84.pdf [accessed Oct. 26, 2005].
    • (1984)
  • 262
    • 84988938853 scopus 로고    scopus 로고
    • The NTP Vision for the 21st Century
    • National Toxicology Program, National Institute for Environmental Health, Research Triangle Park, NC [online]. [accessed March 11, 2005].
    • NTP (National Toxicology Program). 2004. The NTP Vision for the 21st Century. National Toxicology Program, National Institute for Environmental Health, Research Triangle Park, NC [online]. Available: http://ntp-server.niehs.nih.gov/ntp/main_pages/NTPVision.pdf [accessed March 11, 2005].
    • (2004)
  • 263
    • 84988924815 scopus 로고    scopus 로고
    • Presentations at the Workshop: Animal Models for the NTP Rodent Cancer Bioassay: Strains and Stock- Should We Switch?
    • June 16-17, 2005, National Institute of Environmental Health Sciences, Research Triangle Park, NC [online]. [accessed Oct. 26, 2005].
    • NTP (National Toxicology Program). 2005. Presentations at the Workshop: Animal Models for the NTP Rodent Cancer Bioassay: Strains and Stock- Should We Switch? June 16-17, 2005, National Institute of Environmental Health Sciences, Research Triangle Park, NC [online]. Available: http://ntp-server.niehs.nih.gov/files/Agenda_Presentations.pdf [accessed Oct. 26, 2005].
    • (2005)
  • 264
    • 0035416126 scopus 로고    scopus 로고
    • High-throughput docking for lead generation
    • Abagyan, R., and M. Totrov. 2001. High-throughput docking for lead generation. Curr. Opin. Chem. Biol. 5(4):375-382.
    • (2001) Curr. Opin. Chem. Biol. , vol.5 , Issue.4 , pp. 375-382
    • Abagyan, R.1    Totrov, M.2
  • 265
    • 21044432279 scopus 로고    scopus 로고
    • Products and Services
    • Accelrys Software Inc. [online]. [accessed April 12, 2005].
    • Accelrys. 2005. Products and Services. Accelrys Software Inc. [online]. Available: http://www.accelrys.com [accessed April 12, 2005].
    • (2005)
  • 266
    • 0036667364 scopus 로고    scopus 로고
    • Tissue-specific expression of AHR2, ARNT2, and CYP1A in zebrafish embryos and larvae: Effects of developmental stage and 2,3,7,8- tetrachlorodibenzo-p-dioxin exposure
    • Andreasen, E.A., J.M. Spitsbergen, R.L. Tanguay, J.J. Stegeman, W. Heideman, and R.E. Peterson. 2002. Tissue-specific expression of AHR2, ARNT2, and CYP1A in zebrafish embryos and larvae: Effects of developmental stage and 2,3,7,8- tetrachlorodibenzo-p-dioxin exposure. Toxicol. Sci. 68 (2):403-419.
    • (2002) Toxicol. Sci. , vol.68 , Issue.2 , pp. 403-419
    • Andreasen, E.A.1    Spitsbergen, J.M.2    Tanguay, R.L.3    Stegeman, J.J.4    Heideman, W.5    Peterson, R.E.6
  • 267
    • 1842686775 scopus 로고    scopus 로고
    • A model for identifying HERG K+ channel blockers
    • Aronov, A.M., and B.B. Goldman. 2004. A model for identifying HERG K+ channel blockers. Bioorg. Med. Chem. 12(9):2307-2315.
    • (2004) Bioorg. Med. Chem. , vol.12 , Issue.9 , pp. 2307-2315
    • Aronov, A.M.1    Goldman, B.B.2
  • 268
    • 84988936760 scopus 로고    scopus 로고
    • Current Portfolio
    • Astex Technology, Cambridge, UK [online]. [accessed April 12, 2005].
    • Astex Technology. 2005. Current Portfolio. Astex Technology, Cambridge, UK [online]. Available: http://www.astex-technology.com/current_portfolio.html [accessed April 12, 2005].
    • (2005)
  • 269
    • 1842559788 scopus 로고    scopus 로고
    • Reproducibility of SELDI-TOF protein patterns in serum: Comparing datasets from different experiments
    • Baggerly, K.A., J.S. Morris, and K.R. Coombes. 2004. Reproducibility of SELDI-TOF protein patterns in serum: Comparing datasets from different experiments. Bioinformatics 20(5):777-785.
    • (2004) Bioinformatics , vol.20 , Issue.5 , pp. 777-785
    • Baggerly, K.A.1    Morris, J.S.2    Coombes, K.R.3
  • 272
    • 0036525708 scopus 로고    scopus 로고
    • Toxicoproteomics-a new preclinical tool
    • Bandara, L., and S. Kennedy. 2002. Toxicoproteomics-a new preclinical tool. Drug Discov. Today 7(7):411-418.
    • (2002) Drug Discov. Today , vol.7 , Issue.7 , pp. 411-418
    • Bandara, L.1    Kennedy, S.2
  • 273
    • 0012838924 scopus 로고    scopus 로고
    • Adaptive Bayesian designs for dose-ranging drug trials
    • C. Gatsonis, R.E. Kass, B. Carlin, A. Carriquiry, A. Gelman, I. Verdinelli, and M. West, eds. New York, NY: Springer.
    • Berry, D.A., P. Mueller, A.P. Grieve, M. Smith, T. Parke, R. Balazek, N. Mitchard, and M. Krams. 2002. Adaptive Bayesian designs for dose-ranging drug trials. Pp. 99-181 in Case Studies in Bayesian Statistics, Vol. V, C. Gatsonis, R.E. Kass, B. Carlin, A. Carriquiry, A. Gelman, I. Verdinelli, and M. West, eds. New York, NY: Springer.
    • (2002) Case Studies in Bayesian Statistics , vol.5 , pp. 99-181
    • Berry, D.A.1    Mueller, P.2    Grieve, A.P.3    Smith, M.4    Parke, T.5    Balazek, R.6    Mitchard, N.7    Krams, M.8
  • 274
    • 84873856034 scopus 로고    scopus 로고
    • Products
    • Cambridge Crystallographic Data Centre, Cambridge, UK [online]. [accessed April 12, 2005].
    • CCDC (Cambridge Crystallographic Data Centre). 2005. Products. Cambridge Crystallographic Data Centre, Cambridge, UK [online]. Available: http://www.ccdc.cam.ac.uk [accessed April 12, 2005].
    • (2005)
  • 275
    • 27744543374 scopus 로고    scopus 로고
    • Third National Report on Human Exposure to Environmental Chemicals
    • U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, Atlanta, GA [online]. [accessed Sept. 26, 2005].
    • CDC (Centers for Disease Control and Prevention). 2005. Third National Report on Human Exposure to Environmental Chemicals. U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, Atlanta, GA [online]. Available: http://www.cdc.gov/exposurereport/3rd/pdf/thirdreport.pdf [accessed Sept. 26, 2005].
    • (2005)
  • 276
    • 0035491863 scopus 로고    scopus 로고
    • Profiling proteins from azoxymethane-induced colon tumors at the molecular level by matrix-assisted laser desorption/ionization mass spectrometry
    • Chaurand, P., B.B. DaGue, R.S. Pearsall, D.W. Threadgill, and R.M. Caprioli. 2001. Profiling proteins from azoxymethane-induced colon tumors at the molecular level by matrix-assisted laser desorption/ionization mass spectrometry. Proteomics 1(10):1320-1326.
    • (2001) Proteomics , vol.1 , Issue.10 , pp. 1320-1326
    • Chaurand, P.1    DaGue, B.B.2    Pearsall, R.S.3    Threadgill, D.W.4    Caprioli, R.M.5
  • 277
    • 1642345498 scopus 로고    scopus 로고
    • Integrated application of transcriptomics and metabonomics yields new insight into the toxicity due to paracetamol in the mouse
    • Coen, M., S.U. Ruepp, J.C. Lindon, J.K. Nicholson, F. Pognan, E.M. Lenz, and I.D. Wilson. 2004. Integrated application of transcriptomics and metabonomics yields new insight into the toxicity due to paracetamol in the mouse. J. Pharm. Biomed. Anal. 35(1):93-105.
    • (2004) J. Pharm. Biomed. Anal. , vol.35 , Issue.1 , pp. 93-105
    • Coen, M.1    Ruepp, S.U.2    Lindon, J.C.3    Nicholson, J.K.4    Pognan, F.5    Lenz, E.M.6    Wilson, I.D.7
  • 281
    • 0036747317 scopus 로고    scopus 로고
    • Application of surface-enhanced laser desorption/ionization technology to the detection and identification of urinar parvalbumin-alpha: A biomarker of compound-induced skeletal muscle toxicity in the rat
    • Dare, T., H.A. Davies, J.A. Turton, L. Lomas, T.C. Williams, and M.J. York. 2002. Application of surface-enhanced laser desorption/ionization technology to the detection and identification of urinar parvalbumin-alpha: A biomarker of compound-induced skeletal muscle toxicity in the rat. Electrophoresis 23(18):3241-3251.
    • (2002) Electrophoresis , vol.23 , Issue.18 , pp. 3241-3251
    • Dare, T.1    Davies, H.A.2    Turton, J.A.3    Lomas, L.4    Williams, T.C.5    York, M.J.6
  • 282
    • 0033533750 scopus 로고    scopus 로고
    • A novel approach to predicting P450 mediated drug metabolism. CYP2D6 catalyzed N-dealkylation reactions and qualitative metabolite predictions using a combined protein and pharmacophore model for CYP2D6
    • de Groot, M.J., M.J. Ackland, V.A. Horne, A.A. Alex, and B.C. Jones. 1999. A novel approach to predicting P450 mediated drug metabolism. CYP2D6 catalyzed N-dealkylation reactions and qualitative metabolite predictions using a combined protein and pharmacophore model for CYP2D6. J. Med. Chem. 42(20):4062-4070.
    • (1999) J. Med. Chem. , vol.42 , Issue.20 , pp. 4062-4070
    • de Groot, M.J.1    Ackland, M.J.2    Horne, V.A.3    Alex, A.A.4    Jones, B.C.5
  • 285
    • 84988983317 scopus 로고    scopus 로고
    • Microarray, Tox-MIAMExpress
    • European Bioinformatics Institute, European Molecular Biology Laboratory [online]. [accessed April 12, 2005].
    • EBI (European Bioinformatics Institute). 2005. Microarray, Tox-MIAMExpress. European Bioinformatics Institute, European Molecular Biology Laboratory [online]. Available: http://www.ebi.ac.uk/tox-miamexpress/ [accessed April 12, 2005].
    • (2005)
  • 286
    • 84988979319 scopus 로고    scopus 로고
    • Scientifically Validated Methods
    • [online]. [accessed March 16, 2005].
    • ECVAM (European Centre for the Validation Alternative Methods). 2005. Scientifically Validated Methods [online]. Available: http://ecvam.jrc.cec.eu.int/index.htm [accessed March 16, 2005].
    • (2005)
  • 287
    • 0034962557 scopus 로고    scopus 로고
    • Pharmacophore and three- dimensional quantitative structure activity relationship methods for modling cytochrome p450 active sites
    • Ekins, S., M.J. de Groot, and J.P. Jones. 2001. Pharmacophore and three- dimensional quantitative structure activity relationship methods for modling cytochrome p450 active sites. Drug Metab. Dispos. 29(7):936-944.
    • (2001) Drug Metab. Dispos. , vol.29 , Issue.7 , pp. 936-944
    • Ekins, S.1    de Groot, M.J.2    Jones, J.P.3
  • 288
    • 84988912629 scopus 로고    scopus 로고
    • MDL QSAR, MDL Discovery Predictive Science [online]. [accessed April 12, 2005].
    • Elsevier MDL. 2005. MDL QSAR. MDL Discovery Predictive Science [online]. Available: http://www.mdl.com/products/predictive/qsar/index.jsp [accessed April 12, 2005].
    • (2005)
  • 289
    • 0004592386 scopus 로고    scopus 로고
    • Health Effects Test Guidelines OPPTS 870.2400. Acute Eye Irritation
    • EPA 712-C-98-195. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. [accessed April 7, 2005]
    • EPA (U.S. Environmental Protection Agency). 1998. Health Effects Test Guidelines OPPTS 870.2400. Acute Eye Irritation. EPA 712-C-98-195. Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. Available: http://www.epa.gov/opptsfrs/OPPTS_Harmonized/870_Health_Effects_Test_Guidelines/Series/870-2400.pdf [accessed April 7, 2005]
    • (1998)
  • 290
    • 84988948374 scopus 로고    scopus 로고
    • Letters to Manufacturers/Importers, October 14, 1999
    • High Production Volume Challenge Program, Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. [accessed April 11, 2005].
    • EPA (U.S. Environmental Protection Agency). 1999. Letters to Manufacturers/Importers, October 14, 1999. High Production Volume Challenge Program, Office of Prevention, Pesticides, and Toxic Substances, U.S. Environmental Protection Agency, Washington, DC [online]. Available: http://www.epa.gov/chemrtk/ceoltr2.htm [accessed April 11, 2005].
    • (1999)
  • 291
    • 0345508269 scopus 로고    scopus 로고
    • Interim Policy on Genomics
    • Science Policy Council, Office of the Science Advisor, U. S. Environmental Protection Agency, Washington, DC [online]. [accessed April 12, 2005].
    • EPA (U.S. Environmental Protection Agency). 2002. Interim Policy on Genomics. Science Policy Council, Office of the Science Advisor, U. S. Environmental Protection Agency, Washington, DC [online]. Available: http://epa.gov/osa/spc/htm/genomics.htm [accessed April 12, 2005].
    • (2002)
  • 292
    • 33748487774 scopus 로고    scopus 로고
    • A Framework for a Computational Toxicology Research Program in ORD
    • Draft Report. EPA/600/R-03/065. Office of Research and Development, U.S. Environmental Protection Agency. July 2003 [online]. [accessed April 7, 2005].
    • EPA (U.S. Environmental Protection Agency). 2003. A Framework for a Computational Toxicology Research Program in ORD. Draft Report. EPA/600/R-03/065. Office of Research and Development, U.S. Environmental Protection Agency. July 2003 [online]. Available: http://www.epa.gov/sab/03minutes/ctfcpanel_091203mattach_e.pdf [accessed April 7, 2005].
    • (2003)
  • 293
    • 20644433175 scopus 로고    scopus 로고
    • Potential Implications of Genomics for Regulatory and Risk Assessment Applications at EPA
    • External Review Draft. EPA 100/B-04/002. Genomics Task Force Work- group, Science Policy Council, U. S. Environmental Protection Agency, Washington, DC [online]. [accessed April 12, 2005].
    • EPA (U.S. Environmental Protection Agency). 2004. Potential Implications of Genomics for Regulatory and Risk Assessment Applications at EPA. External Review Draft. EPA 100/B-04/002. Genomics Task Force Work- group, Science Policy Council, U. S. Environmental Protection Agency, Washington, DC [online]. Available: http://www.epa.gov/osa/genomics-external-review-draft.pdf [accessed April 12, 2005].
    • (2004)
  • 294
    • 1542333321 scopus 로고    scopus 로고
    • Guidance for Industry: Pharmacogenomic Data Submissions
    • Center for Drug Evaluation and Research, Center for Biologics Evaluation and Research, Center for Devices and Radiological Health, Food and Drug Administration. March 2005 [online]. [accessed June 3, 2005].
    • FDA (Food and Drug Administration). 2005. Guidance for Industry: Pharmacogenomic Data Submissions. Center for Drug Evaluation and Research, Center for Biologics Evaluation and Research, Center for Devices and Radiological Health, Food and Drug Administration. March 2005 [online]. Available: http://www.fda.gov/cder/guidance/6400fnl.htm [accessed June 3, 2005].
    • (2005)
  • 295
    • 0032613916 scopus 로고    scopus 로고
    • Reduction in animal use in the production and testing of biologicals
    • Festing, M.F.W. 1999. Reduction in animal use in the production and testing of biologicals. Dev. Biol. Stand. 101:195-200.
    • (1999) Dev. Biol. Stand. , vol.101 , pp. 195-200
    • Festing, M.F.W.1
  • 296
    • 0000402067 scopus 로고    scopus 로고
    • Reducing the use of laboratory animals in biomedical research: Problems and possible solutions
    • [online]. [accessed April 7, 2005].
    • Festing, M.F.W., V. Baumans, R.D. Combes, M. Halder, C.F.M. Hendriksen, B.R. Howard, D.P. Lovell, G.J. Moore, P. Overend, and M.S. Wilson. 1998. Reducing the use of laboratory animals in biomedical research: Problems and possible solutions. ATLA 26(3):283-301 [online]. Available: http://altweb.jhsph.edu/publications/ECVAM/ecvam29.htm [accessed April 7, 2005].
    • (1998) ATLA , vol.26 , Issue.3 , pp. 283-301
    • Festing, M.F.W.1    Baumans, V.2    Combes, R.D.3    Halder, M.4    Hendriksen, C.F.M.5    Howard, B.R.6    Lovell, D.P.7    Moore, G.J.8    Overend, P.9    Wilson, M.S.10
  • 297
    • 0037200931 scopus 로고    scopus 로고
    • A functional genomics approach using metabolomics and in silico pathway analysis
    • Forster, J., A.K. Gombert, and J. Nielsen. 2002. A functional genomics approach using metabolomics and in silico pathway analysis. Biotechnol. Bioeng. 79(7):703-712.
    • (2002) Biotechnol. Bioeng. , vol.79 , Issue.7 , pp. 703-712
    • Forster, J.1    Gombert, A.K.2    Nielsen, J.3
  • 299
    • 0033920278 scopus 로고    scopus 로고
    • Two-dimensional database of mouse liver proteins: Changes in hepatic protein levels following treatment with aceta- minophen or its nontoxic regioisomer 3-acetamidophenol
    • Fountoulakis, M., P. Berndt, U.A. Boelsterli, F. Crameri, M. Winter, S. Albertini, and L. Suter. 2000. Two-dimensional database of mouse liver proteins: Changes in hepatic protein levels following treatment with aceta- minophen or its nontoxic regioisomer 3-acetamidophenol. Electrophoresis 21(11):2148-2161.
    • (2000) Electrophoresis , vol.21 , Issue.11 , pp. 2148-2161
    • Fountoulakis, M.1    Berndt, P.2    Boelsterli, U.A.3    Crameri, F.4    Winter, M.5    Albertini, S.6    Suter, L.7
  • 301
    • 0018909044 scopus 로고
    • The ED01 study: Summary and conclusions
    • Gaylor, D.W. 1980. The ED01 study: Summary and conclusions. J. Environ. Pathol. Toxicol. 3(3 Spec.):179-183.
    • (1980) J. Environ. Pathol. Toxicol. , vol.3 , Issue.3 , pp. 179-183
    • Gaylor, D.W.1
  • 302
    • 84988948079 scopus 로고    scopus 로고
    • MetaDrug
    • GeneGo Inc., St. Joseph, MI [online]. [accessed April 12, 2005].
    • GeneGo Inc. 2005. MetaDrug. GeneGo Inc., St. Joseph, MI [online]. Available: http://www.genego.com/about/products.shtml#metadrug [accessed April 12, 2005].
    • (2005)
  • 303
    • 0038050467 scopus 로고    scopus 로고
    • Genomics and metabolomics as markers for the interaction of diet and health: Lessons from lipids
    • German, J.B., M.A. Roberts, and S.M. Watkins. 2003. Genomics and metabolomics as markers for the interaction of diet and health: Lessons from lipids. J. Nutr. 133(6 Suppl. 1):2078S-2083S.
    • (2003) J. Nutr. , vol.133 , Issue.6 , pp. 2078S-2083S
    • German, J.B.1    Roberts, M.A.2    Watkins, S.M.3
  • 304
  • 305
    • 4243191598 scopus 로고    scopus 로고
    • Genome-wide linkage analysis of chromogranin B expression in CEPH pedigrees: Implications for exocytotic sympathochromaffin secretion in humans
    • Greenwood, T.A., P.E. Cadman, M. Stridsberg, S. Nguyen, L. Taupenot, N.J., Schork, and D.T. O'Connor. 2004. Genome-wide linkage analysis of chromogranin B expression in CEPH pedigrees: Implications for exocytotic sympathochromaffin secretion in humans. Physiol Genomics. 18(1):119-127.
    • (2004) Physiol Genomics. , vol.18 , Issue.1 , pp. 119-127
    • Greenwood, T.A.1    Cadman, P.E.2    Stridsberg, M.3    Nguyen, S.4    Taupenot, L.5    Schork, N.J.6    O'Connor, D.T.7
  • 307
    • 0037333902 scopus 로고    scopus 로고
    • Toxicogenomics of bromobenzene hepatotoxicity: A combined transcriptomics and proteomics approach
    • Heijne, W., R.H. Stierum, M. Slijper, P.J. van Bladeren, and B. van Ommen. 2003. Toxicogenomics of bromobenzene hepatotoxicity: A combined transcriptomics and proteomics approach. Biochem. Pharmacol. 65(5): 857-875.
    • (2003) Biochem. Pharmacol. , vol.65 , Issue.5 , pp. 857-875
    • Heijne, W.1    Stierum, R.H.2    Slijper, M.3    van Bladeren, P.J.4    van Ommen, B.5
  • 309
    • 1642484344 scopus 로고    scopus 로고
    • Taking stock of toxicogenomics: Mini-monograph offers overview [comment]
    • Hood, E. 2004. Taking stock of toxicogenomics: Mini-monograph offers overview [comment]. Environ. Health Perspect. 112(4):A231.
    • (2004) Environ. Health Perspect. , vol.112 , Issue.4 , pp. A231
    • Hood, E.1
  • 310
    • 84988966786 scopus 로고    scopus 로고
    • Test Methods Evaluations
    • [online]. [accessed March 16, 2005].
    • ICCVAM (Interagency Coordinating Committee on the Validation of Alternative Methods). 2004. Test Methods Evaluations [online]. Available: http://iccvam.niehs.nih.gov/methods/review.htm [accessed March 16, 2005].
    • (2004)
  • 311
    • 84988915536 scopus 로고    scopus 로고
    • ICCVAM - NICEATM Documents
    • [online]. [accessed April 12, 2005].
    • ICCVAM-NICEATM (Interagency Coordinating Committee on the Validation of Alternative Methods- National Toxicology Program Interagency Center for the Evaluation of Alternative Toxicological Methods). 2004. ICCVAM - NICEATM Documents [online]. Available: http://iccvam.niehs.nih.gov/docs/docs.htm [accessed April 12, 2005].
    • (2004)
  • 312
    • 0003180808 scopus 로고    scopus 로고
    • Humane Endpoints for Animals Used in Biomedical Research and Testing
    • [online]. [accessed April 7, 2005].
    • ILAR (Institute for Laboratory Animal Research). 2000. Humane Endpoints for Animals Used in Biomedical Research and Testing. ILAR J. 41(2):59-123 [online]. Available: http://dels.nas.edu/ilar/jour_online/41_2/41_2.asp [accessed April 7, 2005].
    • (2000) ILAR J. , vol.41 , Issue.2 , pp. 59-123
  • 313
    • 0031552362 scopus 로고    scopus 로고
    • Development and validation of a genetic algorithm for flexible docking
    • Jones, G., P. Willett, R.C. Glen, A.R. Leach, and R. Taylor. 1997. Development and validation of a genetic algorithm for flexible docking. J. Mol. Biol. 267(3):727-748.
    • (1997) J. Mol. Biol. , vol.267 , Issue.3 , pp. 727-748
    • Jones, G.1    Willett, P.2    Glen, R.C.3    Leach, A.R.4    Taylor, R.5
  • 314
    • 0142169951 scopus 로고    scopus 로고
    • Proteomic characterization of metabolites, protein adducts, and biliary proteins in rats exposed to 1,1-dichloroethylene or diclofenac
    • Jones, J.A., L. Kaphalia, M. Treinen-Moslen, and D.C. Leibler. 2003. Proteomic characterization of metabolites, protein adducts, and biliary proteins in rats exposed to 1,1-dichloroethylene or diclofenac. Chem. Res. Toxicol. 16(10):1306-1317.
    • (2003) Chem. Res. Toxicol. , vol.16 , Issue.10 , pp. 1306-1317
    • Jones, J.A.1    Kaphalia, L.2    Treinen-Moslen, M.3    Leibler, D.C.4
  • 315
    • 0036649486 scopus 로고    scopus 로고
    • The role of proteomics in toxicology: Identification of biomarkers of toxicity by protein expression analysis
    • Kennedy, S. 2002. The role of proteomics in toxicology: Identification of biomarkers of toxicity by protein expression analysis. Biomarkers 7(4): 269-290.
    • (2002) Biomarkers , vol.7 , Issue.4 , pp. 269-290
    • Kennedy, S.1
  • 316
    • 2542470459 scopus 로고    scopus 로고
    • Protein trafficking and anchoring complexes revealed by proteomic analysis of inward rectifier potassium channel (Kir2.x)-associated proteins
    • Leonoudakis, D., L.R. Conti, S. Anderson, C.M. Radeke, L.M. McGuire, M.E. Adams, S.C. Froehner, J.R. Yates, and C.A. Vandenberg. 2004. Protein trafficking and anchoring complexes revealed by proteomic analysis of inward rectifier potassium channel (Kir2.x)-associated proteins. J. Biol. Chem. 279(21):22331-22346.
    • (2004) J. Biol. Chem. , vol.279 , Issue.21 , pp. 22331-22346
    • Leonoudakis, D.1    Conti, L.R.2    Anderson, S.3    Radeke, C.M.4    McGuire, L.M.5    Adams, M.E.6    Froehner, S.C.7    Yates, J.R.8    Vandenberg, C.A.9
  • 317
    • 84988961090 scopus 로고    scopus 로고
    • DEREK for Windows
    • LHASA Limited, Department of Chemistry, University of Leeds, Leeds, UK [online]. [accessed April 12, 2005].
    • LHASA Ltd. 2005a. DEREK for Windows. LHASA Limited, Department of Chemistry, University of Leeds, Leeds, UK [online]. Available: http://www.chem.leeds.ac.uk/luk/derek/index.html [accessed April 12, 2005].
    • (2005)
  • 318
    • 84988977567 scopus 로고    scopus 로고
    • METEOR
    • LHASA Limited, Department of Chemistry, University of Leeds, Leeds, UK [online]. [accessed April 12, 2005].
    • LHASA Ltd. 2005b. METEOR. LHASA Limited, Department of Chemistry, University of Leeds, Leeds, UK [online]. Available: http://www.chem.leeds.ac.uk/luk/meteor/index.html [accessed April 12, 2005].
    • (2005)
  • 319
    • 2442719174 scopus 로고    scopus 로고
    • Metabonomics technologies and their applications in physiological monitoring, drug safety assessment and disease diagnosis
    • Lindon, J.C., E. Holmes, M.E. Bollard, E.G. Stanley, and J.K. Nicholson. 2004. Metabonomics technologies and their applications in physiological monitoring, drug safety assessment and disease diagnosis. Biomarkers 9(1):1-31.
    • (2004) Biomarkers , vol.9 , Issue.1 , pp. 1-31
    • Lindon, J.C.1    Holmes, E.2    Bollard, M.E.3    Stanley, E.G.4    Nicholson, J.K.5
  • 320
    • 0012789869 scopus 로고    scopus 로고
    • Allelic variation in gene expression is common in the human genome
    • Lo, H.S., Z. Wang, Y. Hu, H.H. Yang, S. Gere, K.H. Buetow, and M.P. Lee. 2003. Allelic variation in gene expression is common in the human genome. Genome Res. 13(8):1855-1862.
    • (2003) Genome Res. , vol.13 , Issue.8 , pp. 1855-1862
    • Lo, H.S.1    Wang, Z.2    Hu, Y.3    Yang, H.H.4    Gere, S.5    Buetow, K.H.6    Lee, M.P.7
  • 321
    • 0033935598 scopus 로고    scopus 로고
    • The practice of structure activity relationships (SAR) in toxicology
    • McKinney, J.D., A. Richard, C. Waller, M.C. Newman, and F. Gerberick. 2000. The practice of structure activity relationships (SAR) in toxicology. Toxicol. Sci. 56(1):8-17.
    • (2000) Toxicol. Sci. , vol.56 , Issue.1 , pp. 8-17
    • McKinney, J.D.1    Richard, A.2    Waller, C.3    Newman, M.C.4    Gerberick, F.5
  • 323
    • 3142689710 scopus 로고    scopus 로고
    • A constitutively active dioxin/aryl hydrocarbon receptor promotes hepatocarcinogenesis in mice
    • Moennikes, O., S. Loeppen, A. Buchmann, P. Andersson, C. Ittrich, L. Poellinger, and M. Schwarz. 2004. A constitutively active dioxin/aryl hydrocarbon receptor promotes hepatocarcinogenesis in mice. Cancer Res. 64(14):4707-4710.
    • (2004) Cancer Res. , vol.64 , Issue.14 , pp. 4707-4710
    • Moennikes, O.1    Loeppen, S.2    Buchmann, A.3    Andersson, P.4    Ittrich, C.5    Poellinger, L.6    Schwarz, M.7
  • 324
    • 84988961205 scopus 로고    scopus 로고
    • MetaSite
    • Molecular Discovery Ltd [online]. [accessed April 12, 2005].
    • Molecular Discovery Ltd. 2005. MetaSite. Molecular Discovery Ltd [online]. Available: http://www.moldiscovery.com/soft_metasite.php [accessed April 12, 2005].
    • (2005)
  • 326
    • 17544399998 scopus 로고
    • Advances in refinement in animal experimentation over the past 25 years
    • Morton, D.B. 1995. Advances in refinement in animal experimentation over the past 25 years. ATLA 23(6):812-822.
    • (1995) ATLA , vol.23 , Issue.6 , pp. 812-822
    • Morton, D.B.1
  • 328
    • 84988968935 scopus 로고    scopus 로고
    • META Program
    • MultiCASE Inc., Beachwood, OH [online]. [accessed April 12, 2005].
    • MultiCASE Inc. 2005. META Program. MultiCASE Inc., Beachwood, OH [online]. Available: http://www.multicase.com/ [accessed April 12, 2005].
    • (2005)
  • 329
    • 0036463681 scopus 로고    scopus 로고
    • Metabonomics: A platform for studying drug toxicity and gene function
    • Nicholson, J.K., J. Connelly, J.C. Lindon, and E. Holmes. 2002. Metabonomics: A platform for studying drug toxicity and gene function. Nat. Rev. Drug Discov. 1(2):153-161.
    • (2002) Nat. Rev. Drug Discov. , vol.1 , Issue.2 , pp. 153-161
    • Nicholson, J.K.1    Connelly, J.2    Lindon, J.C.3    Holmes, E.4
  • 330
    • 1842536853 scopus 로고    scopus 로고
    • A proteomic approach to the identification of cytochrome P450 isoforms in male and female rat liver by nanoscale liquid chromatography-electrospray ionization-tandem mass spectrometry
    • Nisar, S., C.S. Lane, A.F. Wilderspin, K.J. Welham, W.J. Griffiths, and L.H. Patterson. 2004. A proteomic approach to the identification of cytochrome P450 isoforms in male and female rat liver by nanoscale liquid chromatography-electrospray ionization-tandem mass spectrometry. Drug Metab. Dispos. 32(4):382-386.
    • (2004) Drug Metab. Dispos. , vol.32 , Issue.4 , pp. 382-386
    • Nisar, S.1    Lane, C.S.2    Wilderspin, A.F.3    Welham, K.J.4    Griffiths, W.J.5    Patterson, L.H.6
  • 331
    • 0004063705 scopus 로고    scopus 로고
    • The Murine Local Lymph Node Assay: A Test Method for Assessing the Allergic Contact Dermatitis Potential of Chemicals/Compounds
    • NIH Publication No. 99-4494. National Toxicology Program, Research Triangle Park, NC. February 1999 [online]. [accessed March 16, 2005].
    • NTP (National Toxicology Program). 1999. The Murine Local Lymph Node Assay: A Test Method for Assessing the Allergic Contact Dermatitis Potential of Chemicals/Compounds. NIH Publication No. 99-4494. National Toxicology Program, Research Triangle Park, NC. February 1999 [online]. Available: http://iccvam.niehs.nih.gov/methods/llnadocs/llnarep.pdf [accessed March 16, 2005].
    • (1999)
  • 332
    • 84889327803 scopus 로고    scopus 로고
    • Final Report of the OECD Workshop on Harmonization of Validation and Acceptance Criteria for Alternative Toxicological Test Methods
    • Paris: OECD.
    • OECD (Organisation for Economic Cooperation and Development). 1996. Final Report of the OECD Workshop on Harmonization of Validation and Acceptance Criteria for Alternative Toxicological Test Methods. Paris: OECD.
    • (1996)
  • 333
    • 0003913207 scopus 로고    scopus 로고
    • Guidance Document on the Recognition, Assessment, and Use of Clinical Signs as Humane Endpoints for Experimental Animals Used in Safety Evaluation
    • ENV/JM/MONO(2000)7. Paris: OECD [online]. [accessed April 7, 2005].
    • OECD (Organisation for Economic Cooperation and Development). 2000. Guidance Document on the Recognition, Assessment, and Use of Clinical Signs as Humane Endpoints for Experimental Animals Used in Safety Evaluation. ENV/JM/MONO(2000)7. Paris: OECD [online]. Available: http://www.olis.oecd.org/olis/2000doc.nsf/LinkTo/env-jm-mono(2000)7 [accessed April 7, 2005].
    • (2000)
  • 334
    • 84988947101 scopus 로고    scopus 로고
    • OECD Test Guideline 401 will be deleted: A Major Step in Animal Welfare: OECD Reaches Agreement on the Abolishment of the LD50 Acute Toxicity Test
    • [online]. [accessed March 1, 2005].
    • OECD (Organization for Economic Cooperation and Development). 2002a. OECD Test Guideline 401 will be deleted: A Major Step in Animal Welfare: OECD Reaches Agreement on the Abolishment of the LD50 Acute Toxicity Test [online]. Available: http://www.oecd.org/document/52/0,2340,en_2649_34377_2752116_1_1_1_1,00.html [accessed March 1, 2005].
    • (2002)
  • 335
    • 84871008062 scopus 로고    scopus 로고
    • Acute Eye Irritation/Corrosion
    • Chemicals Testing Guidelines No. 405. Paris: Organisation for Economic Cooperation and Development. April 24, 2002.
    • OECD (Organisation for Economic Cooperation and Development). 2002b. Acute Eye Irritation/Corrosion. Chemicals Testing Guidelines No. 405. Paris: Organisation for Economic Cooperation and Development. April 24, 2002.
    • (2002)
  • 336
    • 1642579024 scopus 로고    scopus 로고
    • The Human Proteome Organization Plasma Proteome Project pilot phase: Reference specimens, technology platform compar-isons, and standardized data submissions and analyses
    • Omenn, G.S. 2004. The Human Proteome Organization Plasma Proteome Project pilot phase: Reference specimens, technology platform compar-isons, and standardized data submissions and analyses. Proteomics 4(5): 1235-1240.
    • (2004) Proteomics , vol.4 , Issue.5 , pp. 1235-1240
    • Omenn, G.S.1
  • 337
    • 0032742735 scopus 로고    scopus 로고
    • Homology modeling and substrate binding study of human CYP2C9 enzyme
    • Payne, V.A., Y.T. Chang, and G.H. Loew. 1999. Homology modeling and substrate binding study of human CYP2C9 enzyme. Proteins 37(2):176-190.
    • (1999) Proteins , vol.37 , Issue.2 , pp. 176-190
    • Payne, V.A.1    Chang, Y.T.2    Loew, G.H.3
  • 338
    • 2342646702 scopus 로고    scopus 로고
    • Genome- wide transcription profile of field- and laboratory-selected dichloro- diphenyltrichloroethane (DDT)-resistant Drosophila
    • Pedra, J.H., L.M. McIntyre, M.E. Scharf, and B.R. Pittendrigh. 2004. Genome- wide transcription profile of field- and laboratory-selected dichloro- diphenyltrichloroethane (DDT)-resistant Drosophila. Proc. Natl. Acad. Sci. U.S.A. 101(18):7034-7039.
    • (2004) Proc. Natl. Acad. Sci. U.S.A. , vol.101 , Issue.18 , pp. 7034-7039
    • Pedra, J.H.1    McIntyre, L.M.2    Scharf, M.E.3    Pittendrigh, B.R.4
  • 339
    • 1542331973 scopus 로고    scopus 로고
    • Toxicogenomics in risk assessment: An overview of an HESI collaborative research program
    • Pennie, W., S.D. Pettit, and P.G. Lord. 2004. Toxicogenomics in risk assessment: An overview of an HESI collaborative research program. Environ. Health Perspect. 112(4):417-419.
    • (2004) Environ. Health Perspect. , vol.112 , Issue.4 , pp. 417-419
    • Pennie, W.1    Pettit, S.D.2    Lord, P.G.3
  • 341
    • 0037717085 scopus 로고    scopus 로고
    • Global alteration of gene expression in human keratinocytes by inorganic arsenic
    • Rea, M.A., J.P. Gregg, Q. Qin, M.A. Phillips, and R.H. Rice. 2003. Global alteration of gene expression in human keratinocytes by inorganic arsenic. Carcinogenesis 24(4):747-756.
    • (2003) Carcinogenesis , vol.24 , Issue.4 , pp. 747-756
    • Rea, M.A.1    Gregg, J.P.2    Qin, Q.3    Phillips, M.A.4    Rice, R.H.5
  • 342
    • 84890762143 scopus 로고    scopus 로고
    • Physiologically Based Pharmacokinetics: Science and Applications
    • Hoboken, NJ: John Wiley & Sons, Inc.
    • Reddy, M.B., R.S.H. Yang, H.J. Clewell III, and M.E. Andersen, eds. 2005. Physiologically Based Pharmacokinetics: Science and Applications. Hoboken, NJ: John Wiley & Sons, Inc.
    • (2005)
    • Reddy, M.B.1    Yang, R.S.H.2    Clewell, H.J.3    Andersen, M.E.4
  • 343
    • 0036384102 scopus 로고    scopus 로고
    • NMR-based metabolomics
    • Reo, N.V. 2002. NMR-based metabolomics. Drug Chem. Toxicol. 25(4):375-382.
    • (2002) Drug Chem. Toxicol. , vol.25 , Issue.4 , pp. 375-382
    • Reo, N.V.1
  • 344
    • 0032435458 scopus 로고    scopus 로고
    • Commercial toxicology prediction systems: A regulatory perspective
    • Richard, A.M. 1998. Commercial toxicology prediction systems: A regulatory perspective. Toxicol. Lett. (102-103):611-616.
    • (1998) Toxicol. Lett. , Issue.102-103 , pp. 611-616
    • Richard, A.M.1
  • 346
    • 0036147966 scopus 로고    scopus 로고
    • Genomics and proteomics analysis of acetaminophen toxicity in mouse liver
    • Ruepp, S., R.P. Tonge, J. Shaw, N. Wallis, and F. Pognan. 2002. Genomics and proteomics analysis of acetaminophen toxicity in mouse liver. Toxicol. Sci. 65(1):135-150.
    • (2002) Toxicol. Sci. , vol.65 , Issue.1 , pp. 135-150
    • Ruepp, S.1    Tonge, R.P.2    Shaw, J.3    Wallis, N.4    Pognan, F.5
  • 347
    • 0003915885 scopus 로고
    • The Principles of Humane Experimental Technique
    • Special Ed, Herts, England: Universities Fed-eration for Animal Welfare.
    • Russell, W.M.S., and R.L Burch. 1992. The Principles of Humane Experimental Technique, Special Ed. Herts, England: Universities Federation for Animal Welfare. 238 pp.
    • (1992) , pp. 238
    • Russell, W.M.S.1    Burch, R.L.2
  • 349
  • 350
    • 0003683804 scopus 로고    scopus 로고
    • Product Information
    • Schrödinger, Portland, OR [online]. [accessed April 12, 2005].
    • Schrödinger. 2005. Product Information. Schrödinger, Portland, OR [online]. Available: http://www.schrodinger.com/index.html [accessed April 12, 2005].
    • (2005)
    • Schrödinger1
  • 351
    • 12444282408 scopus 로고
    • Replacing animal experiments
    • G. Langley, ed. New York: Chapman and Hall.
    • Stephens, M.L. 1989. Replacing animal experiments. Pp. 144-168 in Animal Experimentation: The Consensus Changes, G. Langley, ed. New York: Chapman and Hall.
    • (1989) Animal Experimentation: The Consensus Changes , pp. 144-168
    • Stephens, M.L.1
  • 352
    • 0005424460 scopus 로고    scopus 로고
    • The first forty years of the alternatives approach: Refining, reducing, and replacing the use of laboratory animals
    • 1st Ed., D.J. Salem, and A.N. Rowan, eds. Washington, DC: The Humane Society Press.
    • Stephens, M.L, A.M. Goldberg, and A.N. Rowan. 2001. The first forty years of the alternatives approach: Refining, reducing, and replacing the use of laboratory animals. Pp. 121-135 in The State of the Animals 2001, 1st Ed., D.J. Salem, and A.N. Rowan, eds. Washington, DC: The Humane Society Press.
    • (2001) The State of the Animals 2001 , pp. 121-135
    • Stephens, M.L.1    Goldberg, A.M.2    Rowan, A.N.3
  • 353
    • 0036048275 scopus 로고    scopus 로고
    • Possibilities for refinement and reduction: Future improvements within regulatory testing
    • Stephens, M.L., K. Conlee, G. Alvino, and A.N. Rowan. 2002. Possibilities for refinement and reduction: Future improvements within regulatory testing. ILAR J. 43(Suppl.):S74-S79.
    • (2002) ILAR J. , vol.43 , pp. S74-S79
    • Stephens, M.L.1    Conlee, K.2    Alvino, G.3    Rowan, A.N.4
  • 354
    • 0003060484 scopus 로고    scopus 로고
    • Introduction: Reducing unrelieved pain and distress in laboratory animals using humane endpoints
    • Stokes, W.S. 2000. Introduction: Reducing unrelieved pain and distress in laboratory animals using humane endpoints. ILAR J. 41(2):59-61.
    • (2000) ILAR J. , vol.41 , Issue.2 , pp. 59-61
    • Stokes, W.S.1
  • 355
    • 4644239273 scopus 로고    scopus 로고
    • Zebrafish as a model system for drug target screening and validation [review]
    • Sumanas, S., and S. Lin. 2004. Zebrafish as a model system for drug target screening and validation [review]. Drug Discov. Today Targets 3(3):89-96.
    • (2004) Drug Discov. Today Targets , vol.3 , Issue.3 , pp. 89-96
    • Sumanas, S.1    Lin, S.2
  • 357
    • 84988950808 scopus 로고    scopus 로고
    • Discovery Informatics Products
    • Tripos Inc., St. Louis, MO [online]. [accessed April 12, 2005].
    • Tripos Inc. 2005. Discovery Informatics Products. Tripos Inc., St. Louis, MO [online]. Available: http://www.tripos.com/ [accessed April 12, 2005].
    • (2005)
  • 358
    • 3042521346 scopus 로고    scopus 로고
    • Optimising resources by reduction: The FRAME Reduction Committee
    • Vaughan, S. 2004. Optimising resources by reduction: The FRAME Reduction Committee. ATLA 32(Suppl. 1):245-248.
    • (2004) ATLA , vol.32 , pp. 245-248
    • Vaughan, S.1
  • 359
    • 0242628319 scopus 로고    scopus 로고
    • NMR-based metabolomics: A powerful approach for characterizing the effects of Environmental stressors on organism health
    • Viant, M.R., E.S. Rosenblum, and R.S. Tieerdema. 2003. NMR-based metabolomics: A powerful approach for characterizing the effects of Environmental stressors on organism health. Environ. Sci. Technol. 37(21):4982-4989.
    • (2003) Environ. Sci. Technol. , vol.37 , Issue.21 , pp. 4982-4989
    • Viant, M.R.1    Rosenblum, E.S.2    Tieerdema, R.S.3
  • 361
    • 1042266669 scopus 로고    scopus 로고
    • Chromium inhibits transcription from polycyclic aromatic hydrocarbon- inducible promoters by blocking the release of histone deacetylase and preventing the binding of p300 to chromatin
    • Wei, Y.D., K. Tepperman, M.Y. Huang, M.A. Sartor, and A. Puga. 2004. Chromium inhibits transcription from polycyclic aromatic hydrocarbon- inducible promoters by blocking the release of histone deacetylase and preventing the binding of p300 to chromatin. J. Biol. Chem. 279(6):4110-4119.
    • (2004) J. Biol. Chem. , vol.279 , Issue.6 , pp. 4110-4119
    • Wei, Y.D.1    Tepperman, K.2    Huang, M.Y.3    Sartor, M.A.4    Puga, A.5
  • 362
    • 0037260574 scopus 로고    scopus 로고
    • The rainbow trout (On- corhynchus mykiss) tumor model: Recent applications in low-dose exposures to tumor initiators and promoters
    • William, D.E., G.S. Bailey, A. Reddy, J.D. Hendricks, A. Oganesian, G.A. Orner, C.B. Pereira, and J.A. Swenberg. 2003. The rainbow trout (On- corhynchus mykiss) tumor model: Recent applications in low-dose exposures to tumor initiators and promoters. Toxicol. Pathol. 31(Suppl.):58- 61.
    • (2003) Toxicol. Pathol. , vol.31 , pp. 58-61
    • William, D.E.1    Bailey, G.S.2    Reddy, A.3    Hendricks, J.D.4    Oganesian, A.5    Orner, G.A.6    Pereira, C.B.7    Swenberg, J.A.8
  • 363
    • 0036311882 scopus 로고    scopus 로고
    • Alternative (Nonanimal) Methods for Chemicals Testing: Current Status and Future Prospects
    • Worth, A.P., and M. Balls, eds. 2002. Alternative (Nonanimal) Methods for Chemicals Testing: Current Status and Future Prospects. ATLA 30(Suppl. 1).
    • (2002) ATLA , vol.30
    • Worth, A.P.1    Balls, M.2
  • 365
    • 0345505337 scopus 로고    scopus 로고
    • Low-level arsenite induced gene expression in HEK293 cells
    • Zheng, X.H., G.S. Watts, S. Vaught, and A.J. Gandolfi. 2003. Low-level arsenite induced gene expression in HEK293 cells. Toxicology 187(1):39-48.
    • (2003) Toxicology , vol.187 , Issue.1 , pp. 39-48
    • Zheng, X.H.1    Watts, G.S.2    Vaught, S.3    Gandolfi, A.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.