Application of surface-enhanced laser desorption/ionization technology to the detection and identification of urinary parvalbumin-α: A biomarker of compound-induced skeletal muscle toxicity in the rat

Electrophoresis

Volumn 23, Issue 18, 2002, Pages 3241-3251

  Dare, Theo O ^a   Davies, Huw A ^b   Turton, John A ^c   Lomas, Lee ^b   Williams, Thomas C ^a   York, Malcom J ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

^b Ciphergen Biosystems Ltd   (United Kingdom)

^c UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

2,3,5,6 tetramethyl p phenylenediamine; Parvalbumin; ProteinChip; Proteomics; Surface enhanced laser desorption ionization

Indexed keywords

BIOLOGICAL ORGANS; BIOMARKERS; BODY FLUIDS; DESORPTION; KETONES; MASS SPECTROMETRY; MOLECULAR BIOLOGY; MUSCLE; PROTEINS; TOXICITY;

2,3,5,6-TETRAMETHYL-P-PHENYLENEDIAMINE; DETECTION AND IDENTIFICATIONS; P-PHENYLENE DIAMINES; P-PHENYLENEDIAMINE; PARVALBUMIN; PROTEINCHIP; PROTEOMICS; SKELETAL MUSCLE; SURFACE-ENHANCED LASER DESORPTION/IONIZATION; TETRAMETHYL;

RATS;

ASPARTATE AMINOTRANSFERASE; BIOCHEMICAL MARKER; FRUCTOSE BISPHOSPHATE ALDOLASE; N,N,N',N' TETRAMETHYL 1,4 PHENYLENEDIAMINE; PARVALBUMIN;

ANALYTIC METHOD; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CHROMATOGRAPHY; CONTROLLED STUDY; DIAGNOSTIC VALUE; DISEASE SEVERITY; ENZYME BLOOD LEVEL; FEMALE; HISTOPATHOLOGY; MALE; MASS SPECTROMETER; MEDICAL INSTRUMENTATION; MONITORING; NON INVASIVE MEASUREMENT; NONHUMAN; PROTEIN ANALYSIS; PROTEIN URINE LEVEL; RAT STRAIN; SENSITIVITY AND SPECIFICITY; SKELETAL MUSCLE; TOXICITY TESTING; URINALYSIS;

EID: 0036747317     PISSN: 01730835     EISSN: None     Source Type: Journal    
DOI: 10.1002/1522-2683(200209)23:18<3241::AID-ELPS3241>3.0.CO;2-D     Document Type: Article

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