Identification of in vitro protein biomarkers of idiosyncratic liver toxicity

Toxicology in Vitro

Volumn 18, Issue 4, 2004, Pages 533-541

  Gao, Ji ^a   Garulacan, Leah Ann ^a   Storm, Stephen M ^a   Hefta, Stanley A ^a   Opiteck, Gregory J ^a   Lin, Jun Hsiang ^a   Moulin, Frederic ^a   Dambach, Donna M ^a  

^a BRISTOL MYERS SQUIBB   (United States)

Author keywords

Hepatocytes; Idiosyncratic; Multidimensional HPLC; Proteomics; Thiazolidinedione; Toxicity

Indexed keywords

BIOLOGICAL MARKER; CIGLITAZONE; DANTROLENE; DICLOFENAC; DIMETHYL SULFOXIDE; ETHINYLESTRADIOL; FARGLITAZAR; IBUPROFEN; INDINAVIR; KETOPROFEN; PERHEXILINE; PIOGLITAZONE; RAGAGLITAZAR; RALOXIFENE; RITONAVIR; ROSIGLITAZONE; TAMOXIFEN; TERFENADINE; TESAGLITAZAR; TRIFLUOPERAZINE; TROGLITAZONE;

ARTICLE; CELL IMMORTALIZATION; CONTROLLED STUDY; CORRELATION ANALYSIS; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; LIVER CELL; LIVER TOXICITY; PREDICTION; PROTEOMICS; SEPARATION TECHNIQUE; VALIDATION PROCESS; WESTERN BLOTTING;

BIOLOGICAL MARKERS; BLOTTING, WESTERN; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CULTURE MEDIA; DRUG EVALUATION, PRECLINICAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FALSE NEGATIVE REACTIONS; FORECASTING; HEPATOCYTES; HUMANS; LIVER; PHARMACEUTICAL PREPARATIONS; PROTEINS; PROTEOMICS;

EID: 2342581555     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2004.01.012     Document Type: Article

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