-
1
-
-
84866147721
-
-
The White House: Washington, DC
-
National Bioeconomy Blueprint; The White House: Washington, DC, 2012.
-
(2012)
National Bioeconomy Blueprint
-
-
-
3
-
-
85014027976
-
-
Presented at Tooling the U.S. Bioeconomy: Synthetic Biology Conference, Washington, DC, November 5, 2013. ACS Science & the Congress Project
-
Solomon, D. Industrial Views on Synthetic Biology. Presented at Tooling the U.S. Bioeconomy: Synthetic Biology Conference, Washington, DC, November 5, 2013. ACS Science & the Congress Project, 2013.
-
(2013)
Industrial Views on Synthetic Biology
-
-
Solomon, D.1
-
4
-
-
85014041958
-
Companies Rush to Build 'Biofactories' for Medicines, Flavorings and Fuels
-
October 24, accessed December 2, 2014
-
Cha, A. E. Companies Rush to Build 'Biofactories' for Medicines, Flavorings and Fuels. The Washington Post, October 24, 2013. http://www.washingtonpost.com/national/health-science/companies-rush-to-build-biofactories-for-medicines-flavorings-andfuels/2013/10/24/f439dc3a-3032-11e3-8906-3daa2bcde110_story.html (accessed December 2, 2014)
-
(2013)
The Washington Post
-
-
Cha, A.E.1
-
6
-
-
84899696363
-
Large-scale de novo DNA synthesis: technologies and applications
-
Kosuri, S.; Church, G. M. Large-scale de novo DNA synthesis: technologies and applications. Nat. Methods 2014, 11(5), 499-507
-
(2014)
Nat. Methods
, vol.11
, Issue.5
, pp. 499-507
-
-
Kosuri, S.1
Church, G.M.2
-
7
-
-
1842591042
-
The Pace and Proliferation of Biological Technologies
-
Carlson, R. The Pace and Proliferation of Biological Technologies. Biosecurity and Bioterrorism 2003, 1(3), 203-14.
-
(2003)
Biosecurity and Bioterrorism
, vol.1
, Issue.3
, pp. 203-214
-
-
Carlson, R.1
-
9
-
-
84975795680
-
An Integrated Map of Genetic Variation from 1,092 Human Genomes
-
1000 Genomes Project Consortium. An Integrated Map of Genetic Variation from 1,092 Human Genomes. Nature 2012, 491(7422), 56-65
-
(2012)
Nature
, vol.491
, Issue.7422
, pp. 56-65
-
-
-
11
-
-
38549164691
-
GenBank
-
Benson, D. A.; Karsch-Mizrachi, I.; Lipman, D. J.; Ostell, J.; Wheeler, D. L. GenBank. Nucleic Acids Res. 2008, 36(Database Issue), D25-30
-
(2008)
Nucleic Acids Res.
, vol.36
, Issue.DATABASE ISSUE
, pp. D25-D30
-
-
Benson, D.A.1
Karsch-Mizrachi, I.2
Lipman, D.J.3
Ostell, J.4
Wheeler, D.L.5
-
12
-
-
58149185141
-
GenBank
-
Benson, D. A.; Karsch-Mizrachi, I.; Lipman, D. J.; Ostell, J.; Sayers, E. W. GenBank. Nucleic Acids Res. 2009, 37(Database Issue), D26-31.
-
(2009)
Nucleic Acids Res.
, vol.37
, Issue.DATABASE ISSUE
, pp. D26-D31
-
-
Benson, D.A.1
Karsch-Mizrachi, I.2
Lipman, D.J.3
Ostell, J.4
Sayers, E.W.5
-
13
-
-
68949161807
-
Programming cells by multiplex genome engineering and accelerated evolution
-
Wang, H. H.; Isaacs, F. J.; Carr, P. A.; Sun, Z. Z.; Xu, G.; Forest, C. R.; Church, G. M. Programming cells by multiplex genome engineering and accelerated evolution. Nature 2009, 460(7257), 894-8.
-
(2009)
Nature
, vol.460
, Issue.7257
, pp. 894-898
-
-
Wang, H.H.1
Isaacs, F.J.2
Carr, P.A.3
Sun, Z.Z.4
Xu, G.5
Forest, C.R.6
Church, G.M.7
-
14
-
-
77956498326
-
Sequence- and Structure-Specific RNA Processing by a CRISPR Endonuclease
-
Haurwitz, R. E.; Jinek, M.; Wiedenheft, B.; Zhou, K.; Doudna, J. A. Sequence- and Structure-Specific RNA Processing by a CRISPR Endonuclease. Science 2010, 329(5997), 1355-8.
-
(2010)
Science
, vol.329
, Issue.5997
, pp. 1355-1358
-
-
Haurwitz, R.E.1
Jinek, M.2
Wiedenheft, B.3
Zhou, K.4
Doudna, J.A.5
-
15
-
-
84866284306
-
The Role of Bioprocess Engineering in Biotechnology
-
Ladisch, M. The Role of Bioprocess Engineering in Biotechnology. The Bridge 2004, 34(3), 26-32
-
(2004)
The Bridge
, vol.34
, Issue.3
, pp. 26-32
-
-
Ladisch, M.1
-
18
-
-
84860768561
-
-
The National Academies Press: Washington, DC
-
National Research Council. A New Biology for the 21st Century; The National Academies Press: Washington, DC, 2009.
-
(2009)
A New Biology for the 21st Century;
-
-
-
20
-
-
85014046768
-
Biotechnology
-
accessed February 3, 2015
-
Merriam-Webster. Biotechnology in Merriam-Webster. http://www.merriam-webster. com/dictionary/biotechnology (accessed February 3, 2015).
-
Merriam-Webster
-
-
-
21
-
-
85014033488
-
Genetic Engineering
-
accessed February 3, 2015
-
Merriam-Webster. Genetic Engineering in Merriam Webster. http://www.merriamwebster. com/dictionary/genetic%20engineering (accessed February 3, 2015).
-
Merriam Webster
-
-
-
22
-
-
84879808045
-
-
Technology Strategy Board: Swindon, Wiltshire
-
UK Synthetic Biology Roadmap Coordination Group. A Synthetic Biology Roadmap for the UK; Technology Strategy Board: Swindon, Wiltshire, 2012.
-
(2012)
A Synthetic Biology Roadmap for the UK
-
-
-
23
-
-
84875720517
-
Precise and Reliable Gene Expression via Standard Transcription and Translation Initiation Elements
-
Mutalik, V. K.; Guimaraes, J. C.; Cambray, G.; Lam, C.; Christoffersen, M. J.; Mai, Q. A.; Tran, A. B.; Paull, M.; Keasling, J. D.; Arkin, A. P.; Endy, D. Precise and Reliable Gene Expression via Standard Transcription and Translation Initiation Elements. Nat. Methods 2013, 10(4), 354-60.
-
(2013)
Nat. Methods
, vol.10
, Issue.4
, pp. 354-360
-
-
Mutalik, V.K.1
Guimaraes, J.C.2
Cambray, G.3
Lam, C.4
Christoffersen, M.J.5
Mai, Q.A.6
Tran, A.B.7
Paull, M.8
Keasling, J.D.9
Arkin, A.P.10
Endy, D.11
-
25
-
-
84872916342
-
-
online, IEA Bioenergy: Wageningen, The Netherlands, accessed December 12, 2014
-
de Jong, E.; Higson, A.; Walsh, P.; Wellisch, M. Bio-based Chemicals Value Added Products from Biorefineries [online]; IEA Bioenergy: Wageningen, The Netherlands, 2012. http://www.ieabioenergy.com/wp-content/uploads/2013/10/Task-42-Biobased-Chemicalsvalue- added-products-from-biorefineries.pdf (accessed December 12, 2014).
-
(2012)
Bio-based Chemicals Value Added Products from Biorefineries
-
-
de Jong, E.1
Higson, A.2
Walsh, P.3
Wellisch, M.4
-
27
-
-
84922754977
-
-
[online]; OECD Publishing, accessed December 11, 2014
-
OECD. Emerging Policy Issues in Synthetic Biology [online]; OECD Publishing, 2014. http://dx.doi.org/10.1787/9789264208421-en (accessed December 11, 2014).
-
(2014)
Emerging Policy Issues in Synthetic Biology
-
-
-
29
-
-
85014010967
-
-
Presented at Workshop on the Industrialization of Biology, May 28
-
Palsson, B. Cell Factory Design. Presented at Workshop on the Industrialization of Biology, May 28, 2014.
-
(2014)
Cell Factory Design
-
-
Palsson, B.1
-
33
-
-
84902147599
-
Engineering Biology to Address Global Problems: Synthetic Biology Markets, Needs, and Applications
-
Kelley, N. J.; Whelan, D. J.; Kerr, E.; Apel, A.; Beliveau, R.; Scanlon, R. Engineering Biology to Address Global Problems: Synthetic Biology Markets, Needs, and Applications. Ind. Biotechnol. 2014, 10(3), 140-9.
-
(2014)
Ind. Biotechnol.
, vol.10
, Issue.3
, pp. 140-149
-
-
Kelley, N.J.1
Whelan, D.J.2
Kerr, E.3
Apel, A.4
Beliveau, R.5
Scanlon, R.6
-
34
-
-
79960915471
-
-
[online]; MIT Washington Office:Washington, DC, accessed December 4, 2014
-
MIT (Massachusetts Institute of Technology). The Third Revolution: The Convergence of the Life Sciences, Physical Sciences, and Engineering [online]; MIT Washington Office:Washington, DC, 2011. http://dc.mit.edu/sites/dc.mit.edu/files/MIT%20White%20 Paper%20on%20Convergence.pdf (accessed December 4, 2014).
-
(2011)
The Third Revolution: The Convergence of the Life Sciences, Physical Sciences, and Engineering
-
-
-
35
-
-
84928898567
-
-
[online]; AAAS: Washington, DC, accessed October 10, 2014
-
AAAS (American Academy of Arts and Sciences). ARISE II: Unleashing America's Research & Innovation Enterprise [online]; AAAS: Washington, DC, 2013. https://www. amacad.org/multimedia/pdfs/publications/researchpapersmonographs/arise2.pdf (accessed October 10, 2014).
-
(2013)
ARISE II: Unleashing America's Research & Innovation Enterprise
-
-
-
37
-
-
84922754977
-
-
[online]; OECD Publishing, accessed December 11, 2014
-
OECD. Emerging Policy Issues in Synthetic Biology [online]; OECD Publishing, 2014. http://dx.doi.org/10.1787/9789264208421-en (accessed December 11, 2014).
-
(2014)
Emerging Policy Issues in Synthetic Biology
-
-
-
38
-
-
43949109842
-
China's Fifteen-Year Plan for Science and Technology: An Assessment
-
Serger, S. S.; Breidne, M. China's Fifteen-Year Plan for Science and Technology: An Assessment. Asia Pol'y 2007, 4(1), 135-64.
-
(2007)
Asia Pol'y
, vol.4
, Issue.1
, pp. 135-164
-
-
Serger, S.S.1
Breidne, M.2
-
39
-
-
8144226497
-
Total synthesis of long DNA sequences: Synthesis of a contiguous 32-kb polyketide synthase gene cluster
-
Kodumal, S. J.; Patel, K. G.; Reid, R.; Menzella, H. G.; Welch, M.; Santi, D. V. Total synthesis of long DNA sequences: Synthesis of a contiguous 32-kb polyketide synthase gene cluster. Proc. Natl. Acad. Sci. U. S. A. 2004, 101(44), 15573-8
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, Issue.44
, pp. 15573-15578
-
-
Kodumal, S.J.1
Patel, K.G.2
Reid, R.3
Menzella, H.G.4
Welch, M.5
Santi, D.V.6
-
40
-
-
70149113922
-
Synthesis of Methyl Halides from Biomass Using Engineered Microbes
-
Bayer, T. S.; Widmaier, D. M.; Temme, K.; Mirsky, E. A.; Santi, D. V.; Voigt, C. A. Synthesis of Methyl Halides from Biomass Using Engineered Microbes. J. Am. Chem. Soc. 2009, 131(18), 6508-15.
-
(2009)
J. Am. Chem. Soc.
, vol.131
, Issue.18
, pp. 6508-6515
-
-
Bayer, T.S.1
Widmaier, D.M.2
Temme, K.3
Mirsky, E.A.4
Santi, D.V.5
Voigt, C.A.6
-
41
-
-
77953584054
-
Creation of a Bacterial Cell Controlled by a Chemically Synthesized Genome
-
Gibson, D. G.; Glass, J. I.; Lartigue, C.; Noskov, V. N.; Chuang, R.-Y.; Algire, M. A.; Benders, G. A.; Montague, M. G.; Ma, L.; Moodie, M. M.; Merryman, C.; Vashee, S.; Krishnakumar, R.; Assad-Garcia, N.; Andrews-Pfannkoch, C.; Denisova, E. A.; Young, L.; Qi, Z.-Q.; Segall-Shapiro, T. H.; Calvey, C. H.; Parmar, P. P.; Hutchison, C. A.; Smith, H. O.; Venter, J. C. Creation of a Bacterial Cell Controlled by a Chemically Synthesized Genome. Science 2010, 329(5987), 52-56
-
(2010)
Science
, vol.329
, Issue.5987
, pp. 52-56
-
-
Gibson, D.G.1
Glass, J.I.2
Lartigue, C.3
Noskov, V.N.4
Chuang, R.-Y.5
Algire, M.A.6
Benders, G.A.7
Montague, M.G.8
Ma, L.9
Moodie, M.M.10
Merryman, C.11
Vashee, S.12
Krishnakumar, R.13
Assad-Garcia, N.14
Andrews-Pfannkoch, C.15
Denisova, E.A.16
Young, L.17
Qi, Z.-Q.18
Segall-Shapiro, T.H.19
Calvey, C.H.20
Parmar, P.P.21
Hutchison, C.A.22
Smith, H.O.23
Venter, J.C.24
more..
-
42
-
-
84897581176
-
Total Synthesis of a Functional Designer Eukaryotic Chromosome
-
Annaluru, N.; Muller, H.; Mitchell, L. A.; Ramalingam, S.; Stracquadanio, G.; Richardson, S. M.; Dymond, J. S.; Kuang, Z.; Scheifele, L. Z.; Cooper, E. M.; Cai, Y.; Zeller, K.; Agmon, N.; Han, J. S.; Hadjithomas, M.; Tullman, J.; Caravelli, K.; Cirelli, K.; Guo, Z.; London, V.; Yeluru, A.; Murugan, S.; Kandavelou, K.; Agier, N.; Fischer, G.; Yang, K.; Martin, J. A.; Bilgel, M.; Bohutski, P.; Boulier, K. M.; Capaldo, B. J.; Chang, J.; Charoen, K.; Choi, W. J.; Deng, P.; DiCarlo, J. E.; Doong, J.; Dunn, J.; Feinberg, J. I.; Fernandez, C.; Floria, C. E.; Gladowski, D.; Hadidi, P.; Ishizuka, I.; Jabbari, J.; Lau, C. Y.; Lee, P. A.; Li, S.; Lin, D.; Linder, M. E.; Ling, J.; Liu, J.; Liu, J.; London, M.; Ma, H.; Mao, J.; McDade, J. E.; McMillan, A.; Moore, A. M.; Oh, W. C.; Ouyang, Y.; Patel, R.; Paul, M.; Paulsen, L. C.; Qiu, J.; Rhee, A.; Rubashkin, M. G.; Soh, I. Y.; Sotuyo, N. E.; Srinivas, V.; Suarez, A.; Wong, A.; Wong, R.; Xie, W. R.; Xu, Y.; Yu, A. T.; Koszul, R.; Bader, J. S.; Boeke, J. D.; Chandrasegaran, S. Total Synthesis of a Functional Designer Eukaryotic Chromosome. Science 2014, 344(6179), 55-8.
-
(2014)
Science
, vol.344
, Issue.6179
, pp. 55-58
-
-
Annaluru, N.1
Muller, H.2
Mitchell, L.A.3
Ramalingam, S.4
Stracquadanio, G.5
Richardson, S.M.6
Dymond, J.S.7
Kuang, Z.8
Scheifele, L.Z.9
Cooper, E.M.10
Cai, Y.11
Zeller, K.12
Agmon, N.13
Han, J.S.14
Hadjithomas, M.15
Tullman, J.16
Caravelli, K.17
Cirelli, K.18
Guo, Z.19
London, V.20
Yeluru, A.21
Murugan, S.22
Kandavelou, K.23
Agier, N.24
Fischer, G.25
Yang, K.26
Martin, J.A.27
Bilgel, M.28
Bohutski, P.29
Boulier, K.M.30
Capaldo, B.J.31
Chang, J.32
Charoen, K.33
Choi, W.J.34
Deng, P.35
DiCarlo, J.E.36
Doong, J.37
Dunn, J.38
Feinberg, J.I.39
Fernandez, C.40
Floria, C.E.41
Gladowski, D.42
Hadidi, P.43
Ishizuka, I.44
Jabbari, J.45
Lau, C.Y.46
Lee, P.A.47
Li, S.48
Lin, D.49
Linder, M.E.50
Ling, J.51
Liu, J.52
Liu, J.53
London, M.54
Ma, H.55
Mao, J.56
McDade, J.E.57
McMillan, A.58
Moore, A.M.59
Oh, W.C.60
Ouyang, Y.61
Patel, R.62
Paul, M.63
Paulsen, L.C.64
Qiu, J.65
Rhee, A.66
Rubashkin, M.G.67
Soh, I.Y.68
Sotuyo, N.E.69
Srinivas, V.70
Suarez, A.71
Wong, A.72
Wong, R.73
Xie, W.R.74
Xu, Y.75
Yu, A.T.76
Koszul, R.77
Bader, J.S.78
Boeke, J.D.79
Chandrasegaran, S.80
more..
-
43
-
-
84890178034
-
Advances in Genetic Circuit Design:Novel Biochemistries, Deep Part Mining, and Precision Gene Expression
-
Nielsen, A. A. K.; Segall-Shapiro, T. H.; Voigt, C. A. Advances in Genetic Circuit Design:Novel Biochemistries, Deep Part Mining, and Precision Gene Expression. Curr. Opin. Chem. Biol. 2013, 17(6), 878-92.
-
(2013)
Curr. Opin. Chem. Biol.
, vol.17
, Issue.6
, pp. 878-892
-
-
Nielsen, A.A.K.1
Segall-Shapiro, T.H.2
Voigt, C.A.3
-
44
-
-
84884165315
-
DNA targeting specificity of RNA-guided Cas9 nucleases
-
Hsu, P. D.; Scott, D. A.; Weinstein, J. A.; Ran, F. A.; Konermann, S.; Agarwala, V.; Li, Y.; Fine, E. J.; Wu, X.; Shalem, O.; Cradick, T. J.; Marraffini, L. A.; Bao, G.; Zhang, F. DNA targeting specificity of RNA-guided Cas9 nucleases. Nat. Biotechnol. 2013, 31(9), 827-32.
-
(2013)
Nat. Biotechnol.
, vol.31
, Issue.9
, pp. 827-832
-
-
Hsu, P.D.1
Scott, D.A.2
Weinstein, J.A.3
Ran, F.A.4
Konermann, S.5
Agarwala, V.6
Li, Y.7
Fine, E.J.8
Wu, X.9
Shalem, O.10
Cradick, T.J.11
Marraffini, L.A.12
Bao, G.13
Zhang, F.14
-
45
-
-
34347258175
-
Quantitative Prediction of Cellular Metabolism with Constraint-Based Models: the COBRA Toolbox
-
Becker, S. A.; Feist, A. M.; Mo, M. L.; Hannum, G.; Palsson, B. O.; Herrgard, M. J., Quantitative Prediction of Cellular Metabolism with Constraint-Based Models: the COBRA Toolbox. Nat. Protoc. 2007, 2(3), 727-738
-
(2007)
Nat. Protoc.
, vol.2
, Issue.3
, pp. 727-738
-
-
Becker, S.A.1
Feist, A.M.2
Mo, M.L.3
Hannum, G.4
Palsson, B.O.5
Herrgard, M.J.6
-
46
-
-
0242487787
-
Optknock: A Bilevel Programming Framework for Identifying Gene Knockout Strategies for Microbial Strain Optimization
-
Burgard, A. P.; Pharkya, P.; Maranas, C. D. Optknock: A Bilevel Programming Framework for Identifying Gene Knockout Strategies for Microbial Strain Optimization. Biotechnology & Bioengineering 2003, 84(6), 647-57.
-
(2003)
Biotechnology & Bioengineering
, vol.84
, Issue.6
, pp. 647-657
-
-
Burgard, A.P.1
Pharkya, P.2
Maranas, C.D.3
-
47
-
-
84921517479
-
Functional Optimization of Gene Clusters by Combinatorial Design and Assembly
-
Smanski, M. J.; Bhatia, S.; Zhao, D.; Park, Y.; B A Woodruff, L.; Giannoukos, G.; Ciulla, D.; Busby, M.; Calderon, J.; Nicol, R.; Gordon, D. B.; Densmore, D.; Voigt, C. A. Functional Optimization of Gene Clusters by Combinatorial Design and Assembly. Nat. Biotechnol. 2014, 32(12), 1241-9.
-
(2014)
Nat. Biotechnol.
, vol.32
, Issue.12
, pp. 1241-1249
-
-
Smanski, M.J.1
Bhatia, S.2
Zhao, D.3
Park, Y.4
Woodruff, B.A.L.5
Giannoukos, G.6
Ciulla, D.7
Busby, M.8
Calderon, J.9
Nicol, R.10
Gordon, D.B.11
Densmore, D.12
Voigt, C.A.13
-
48
-
-
84899694320
-
Principles of Genetic Circuit Design
-
Brophy, J. A. N.; Voigt, C. A. Principles of Genetic Circuit Design. Nat. Methods 2014, 11(5), 508-520.
-
(2014)
Nat. Methods
, vol.11
, Issue.5
, pp. 508-520
-
-
Brophy, J.A.N.1
Voigt, C.A.2
-
49
-
-
84863322344
-
Contextualizing Context for Synthetic Biology - Identifying Causes of Failure of Synthetic Biological Systems
-
Cardinale, S.; Arkin, A. P., Contextualizing Context for Synthetic Biology - Identifying Causes of Failure of Synthetic Biological Systems. Biotechnol. J. 2012, 7(7), 856-66.
-
(2012)
Biotechnol. J.
, vol.7
, Issue.7
, pp. 856-866
-
-
Cardinale, S.1
Arkin, A.P.2
-
50
-
-
84875720517
-
Precise and reliable gene expression via standard transcription and translation initiation elements
-
Mutalik, V. K.; Guimaraes, J. C.; Cambray, G.; Lam, C.; Christoffersen, M. J.; Mai, Q. A.; Tran, A. B.; Paull, M.; Keasling, J. D.; Arkin, A. P.; Endy, D. Precise and reliable gene expression via standard transcription and translation initiation elements. Nat. Methods 2013, 10(4), 354-60
-
(2013)
Nat. Methods
, vol.10
, Issue.4
, pp. 354-360
-
-
Mutalik, V.K.1
Guimaraes, J.C.2
Cambray, G.3
Lam, C.4
Christoffersen, M.J.5
Mai, Q.A.6
Tran, A.B.7
Paull, M.8
Keasling, J.D.9
Arkin, A.P.10
Endy, D.11
-
51
-
-
33744509927
-
Engineering Life: Building a FAB for Biology
-
Baker, D.; Church, G.; Collins, J.; Endy, D.; Jacobson, J.; Keasling, J.; Modrich, P.; Smolke, C.; Weiss, R. Engineering Life: Building a FAB for Biology. Sci. Am. 2006, 294(6), 44-51.
-
(2006)
Sci. Am.
, vol.294
, Issue.6
, pp. 44-51
-
-
Baker, D.1
Church, G.2
Collins, J.3
Endy, D.4
Jacobson, J.5
Keasling, J.6
Modrich, P.7
Smolke, C.8
Weiss, R.9
-
52
-
-
84902159136
-
The Synthetic Biology Open Language (SBOL) Provides a Community Standard for Communicating Designs in Synthetic Biology
-
Galdzicki, M.; Clancy, K. P.; Oberortner, E.; Pocock, M.; Quinn, J. Y.; Rodriguez, C. A.; Roehner, N.; Wilson, M. L.; Adam, L.; Anderson, J. C.; Bartley, B. A.; Beal, J.; Chandran, D.; Chen, J.; Densmore, D.; Endy, D.; Grunberg, R.; Hallinan, J.; Hillson, N. J.; Johnson, J. D.; Kuchinsky, A.; Lux, M.; Misirli, G.; Peccoud, J.; Plahar, H. A.; Sirin, E.; Stan, G.-B.; Villalobos, A.; Wipat, A.; Gennari, J. H.; Myers, C. J.; Sauro, H. M. The Synthetic Biology Open Language (SBOL) Provides a Community Standard for Communicating Designs in Synthetic Biology. Nat. Biotechnol. 2014, 32(6), 545-50.
-
(2014)
Nat. Biotechnol.
, vol.32
, Issue.6
, pp. 545-550
-
-
Galdzicki, M.1
Clancy, K.P.2
Oberortner, E.3
Pocock, M.4
Quinn, J.Y.5
Rodriguez, C.A.6
Roehner, N.7
Wilson, M.L.8
Adam, L.9
Anderson, J.C.10
Bartley, B.A.11
Beal, J.12
Chandran, D.13
Chen, J.14
Densmore, D.15
Endy, D.16
Grunberg, R.17
Hallinan, J.18
Hillson, N.J.19
Johnson, J.D.20
Kuchinsky, A.21
Lux, M.22
Misirli, G.23
Peccoud, J.24
Plahar, H.A.25
Sirin, E.26
Stan, G.-B.27
Villalobos, A.28
Wipat, A.29
Gennari, J.H.30
Myers, C.J.31
Sauro, H.M.32
more..
-
53
-
-
84908079780
-
A Systematic Analysis of Biosynthetic Gene Clusters in the Human Microbiome Reveals a Common Family of Antibiotics
-
Donia, M. S.; Cimermancic, P.; Schulze, C. J.; Wieland Brown, L. C.; Martin, J.; Mitreva, M.; Clardy, J.; Linington, R. G.; Fischbach, M. A. A Systematic Analysis of Biosynthetic Gene Clusters in the Human Microbiome Reveals a Common Family of Antibiotics. Cell 2014, 158(6), 1402-14
-
(2014)
Cell
, vol.158
, Issue.6
, pp. 1402-1414
-
-
Donia, M.S.1
Cimermancic, P.2
Schulze, C.J.3
Wieland Brown, L.C.4
Martin, J.5
Mitreva, M.6
Clardy, J.7
Linington, R.G.8
Fischbach, M.A.9
-
54
-
-
84886091355
-
What Lives On Our Skin: Ecology, Genomics and Therapeutic Opportunities Of the Skin Microbiome
-
Scharschmidt, T. C.; Fischbach, M. A. What Lives On Our Skin: Ecology, Genomics and Therapeutic Opportunities Of the Skin Microbiome. Drug Discovery Today: Dis. Mech. 2013, 10(3-4), e83-9.
-
(2013)
Drug Discovery Today: Dis. Mech.
, vol.10
, Issue.3-4
, pp. e83-9
-
-
Scharschmidt, T.C.1
Fischbach, M.A.2
-
55
-
-
17444382016
-
Exploring the Diversity of Complex Metabolic Networks
-
Hatzimanikatis, V.; Li, C.; Ionita, J. A.; Henry, C. S.; Jankowski, M. D.; Broadbelt, L. J. Exploring the Diversity of Complex Metabolic Networks. Bioinformatics 2005, 21(8), 1603-1609
-
(2005)
Bioinformatics
, vol.21
, Issue.8
, pp. 1603-1609
-
-
Hatzimanikatis, V.1
Li, C.2
Ionita, J.A.3
Henry, C.S.4
Jankowski, M.D.5
Broadbelt, L.J.6
-
56
-
-
8744251043
-
Computational Discovery of Biochemical Routes to Specialty Chemicals
-
Li, C.; Henry, C. S.; Jankowski, M. D.; Ionita, J. A.; Hatzimanikatis, V.; Broadbelt, L. J. Computational Discovery of Biochemical Routes to Specialty Chemicals. Chem. Eng. Sci. 2004, 59(22-23), 5051-60.
-
(2004)
Chem. Eng. Sci.
, vol.59
, Issue.22-23
, pp. 5051-5060
-
-
Li, C.1
Henry, C.S.2
Jankowski, M.D.3
Ionita, J.A.4
Hatzimanikatis, V.5
Broadbelt, L.J.6
-
57
-
-
85013997679
-
-
San Francisco, CA
-
Srivastava, S.; Kotker, J.; Hamilton, S.; Ruan, P.; Tsui, J.; Anderson, J. C.; Bodik, R.; Seshia, S. A. In Pathway Synthesis Using the Act Ontology in Proceedings of the 4th International Workshop on Bio-Design Automation (IWBDA): San Francisco, CA, 2012.
-
(2012)
In Pathway Synthesis Using the Act Ontology in Proceedings of the 4th International Workshop on Bio-Design Automation (IWBDA)
-
-
Srivastava, S.1
Kotker, J.2
Hamilton, S.3
Ruan, P.4
Tsui, J.5
Anderson, J.C.6
Bodik, R.7
Seshia, S.A.8
-
58
-
-
71849110893
-
Next-generation synthetic gene networks
-
Lu, T. K.; Khalil, A. S.; Collins, J. J. Next-generation synthetic gene networks. Nat. Biotechnol. 2009, 27(12), 1139-50.
-
(2009)
Nat. Biotechnol.
, vol.27
, Issue.12
, pp. 1139-1150
-
-
Lu, T.K.1
Khalil, A.S.2
Collins, J.J.3
-
59
-
-
84859633048
-
Design of a Dynamic Sensor-Regulator System for Production of Chemicals and Fuels Derived from Fatty Acids
-
Zhang, F.; Carothers, J. M.; Keasling, J. D. Design of a Dynamic Sensor-Regulator System for Production of Chemicals and Fuels Derived from Fatty Acids. Nat. Biotechnol. 2012, 30(4), 354-9.
-
(2012)
Nat. Biotechnol.
, vol.30
, Issue.4
, pp. 354-359
-
-
Zhang, F.1
Carothers, J.M.2
Keasling, J.D.3
-
60
-
-
84899477796
-
Synthesis and patterning of tunable multiscale materials with engineered cells
-
Chen, A. Y.; Deng, Z.; Billings, A. N.; Seker, U. O. S.; Lu, Michelle Y.; Citorik, R. J.; Zakeri, B.; Lu, T. K. Synthesis and patterning of tunable multiscale materials with engineered cells. Nat. Mater. 2014, 13(5), 515-23.
-
(2014)
Nat. Mater.
, vol.13
, Issue.5
, pp. 515-523
-
-
Chen, A.Y.1
Deng, Z.2
Billings, A.N.3
Seker, U.O.S.4
Lu Michelle, Y.5
Citorik, R.J.6
Zakeri, B.7
Lu, T.K.8
-
61
-
-
60349099007
-
The Time Line Adrenalin and cherry trees
-
Bennett, J. W. The Time Line Adrenalin and cherry trees. Mod. Drug Discovery 2001, 4, 47-8.
-
(2001)
Mod. Drug Discovery
, vol.4
, pp. 47-48
-
-
Bennett, J.W.1
-
63
-
-
2442728636
-
Construction of biologically functional bacterial plasmids in vitro
-
Cohen, S. N.; Chang, A. C.; Boyer, H. W.; Helling, R. B. Construction of biologically functional bacterial plasmids in vitro. Proc. Natl. Acad. Sci. U. S. A. 1973, 70(11), 3240-4.
-
(1973)
Proc. Natl. Acad. Sci. U. S. A.
, vol.70
, Issue.11
, pp. 3240-3244
-
-
Cohen, S.N.1
Chang, A.C.2
Boyer, H.W.3
Helling, R.B.4
-
64
-
-
0025895183
-
Toward a Science of Metabolic Engineering
-
Bailey, J. E. Toward a Science of Metabolic Engineering. Science 1991, 252(5013), 1668-75.
-
(1991)
Science
, vol.252
, Issue.5013
, pp. 1668-1675
-
-
Bailey, J.E.1
-
65
-
-
0025866296
-
Network rigidity and metabolic engineering in metabolite overproduction
-
Stephanopoulos, G.; Vallino, J. Network rigidity and metabolic engineering in metabolite overproduction. Science 1991, 252(5013), 1675-81.
-
(1991)
Science
, vol.252
, Issue.5013
, pp. 1675-1681
-
-
Stephanopoulos, G.1
Vallino, J.2
-
66
-
-
84860741240
-
Engineering the third wave of biocatalysis
-
Bornscheuer, U. T.; Huisman, G. W.; Kazlauskas, R. J.; Lutz, S.; Moore, J. C.; Robins, K. Engineering the third wave of biocatalysis. Nature 2012, 485(7397), 185-94.
-
(2012)
Nature
, vol.485
, Issue.7397
, pp. 185-194
-
-
Bornscheuer, U.T.1
Huisman, G.W.2
Kazlauskas, R.J.3
Lutz, S.4
Moore, J.C.5
Robins, K.6
-
67
-
-
77954797329
-
Biocatalytic Asymmetric Synthesis of Chiral Amines from Ketones Applied to Sitagliptin Manufacture
-
Savile, C. K.; Janey, J. M.; Mundorff, E. C.; Moore, J. C.; Tam, S.; Jarvis, W. R.; Colbeck, J. C.; Krebber, A.; Fleitz, F. J.; Brands, J.; Devine, P. N.; Huisman, G. W.; Hughes, G. J. Biocatalytic Asymmetric Synthesis of Chiral Amines from Ketones Applied to Sitagliptin Manufacture. Science 2010, 329(5989), 305-9.
-
(2010)
Science
, vol.329
, Issue.5989
, pp. 305-309
-
-
Savile, C.K.1
Janey, J.M.2
Mundorff, E.C.3
Moore, J.C.4
Tam, S.5
Jarvis, W.R.6
Colbeck, J.C.7
Krebber, A.8
Fleitz, F.J.9
Brands, J.10
Devine, P.N.11
Huisman, G.W.12
Hughes, G.J.13
-
68
-
-
23844549294
-
-
UNICEF: Geneva
-
WHO (World Health Organization). World Malaria Report 2005. UNICEF: Geneva, 2005.
-
(2005)
World Malaria Report 2005
-
-
-
69
-
-
0038541587
-
Measurement of trends in childhood malaria mortality in Africa: an assessment of progress toward targets based on verbal autopsy
-
Korenromp, E. L.; Williams, B. G.; Gouws, E.; Dye, C.; Snow, R. W. Measurement of trends in childhood malaria mortality in Africa: an assessment of progress toward targets based on verbal autopsy. Lancet Infect. Dis. 2003, 3(6), 349-358
-
(2003)
Lancet Infect. Dis.
, vol.3
, Issue.6
, pp. 349-358
-
-
Korenromp, E.L.1
Williams, B.G.2
Gouws, E.3
Dye, C.4
Snow, R.W.5
-
71
-
-
19744382857
-
Source of New Hope Against Malaria is in Short Supply
-
Enserink, M. Source of New Hope Against Malaria is in Short Supply. Science 2005, 307(5706), 33.
-
(2005)
Science
, vol.307
, Issue.5706
, pp. 33
-
-
Enserink, M.1
-
72
-
-
0020577131
-
Total Synthesis of Qinghaosu
-
Schmid, G.; Hofheinz, W. Total Synthesis of Qinghaosu. J. Am. Chem. Soc. 1983, 105(3), 624-5.
-
(1983)
J. Am. Chem. Soc.
, vol.105
, Issue.3
, pp. 624-625
-
-
Schmid, G.1
Hofheinz, W.2
-
73
-
-
38949093153
-
-
U.S. Patent 5,420,299, May 30
-
Haynes, R. K.; Vonwiller, S. C. Cyclic peroxyacetal lactone, lactol and ether compounds. U.S. Patent 5,420,299, May 30, 1995
-
(1995)
Cyclic peroxyacetal lactone, lactol and ether compounds
-
-
Haynes, R.K.1
Vonwiller, S.C.2
-
74
-
-
0024429567
-
A simple conversion of artemisinic acid into artemisinin
-
Roth, R. J.; Acton, N., A simple conversion of artemisinic acid into artemisinin. J. Nat. Prod. 1989, 52(5), 1183-5.
-
(1989)
J. Nat. Prod.
, vol.52
, Issue.5
, pp. 1183-1185
-
-
Roth, R.J.1
Acton, N.2
-
75
-
-
84876784070
-
High-level semi-synthetic production of the potent antimalarial artemisinin
-
Paddon, C. J.; Westfall, P. J.; Pitera, D. J.; Benjamin, K.; Fisher, K.; McPhee, D.; Leavell, M. D.; Tai, A.; Main, A.; Eng, D.; Polichuk, D. R.; Teoh, K. H.; Reed, D. W.; Treynor, T.; Lenihan, J.; Fleck, M.; Bajad, S.; Dang, G.; Dengrove, D.; Diola, D.; Dorin, G.; Ellens, K. W.; Fickes, S.; Galazzo, J.; Gaucher, S. P.; Geistlinger, T.; Henry, R.; Hepp, M.; Horning, T.; Iqbal, T.; Jiang, H.; Kizer, L.; Lieu, B.; Melis, D.; Moss, N.; Regentin, R.; Secrest, S.; Tsuruta, H.; Vazquez, R.; Westblade, L. F.; Xu, L.; Yu, M.; Zhang, Y.; Zhao, L.; Lievense, J.; Covello, P. S.; Keasling, J. D.; Reiling, K. K.; Renninger, N. S.; Newman, J. D. High-level semi-synthetic production of the potent antimalarial artemisinin. Nature 2013, 496(7446), 528-32.
-
(2013)
Nature
, vol.496
, Issue.7446
, pp. 528-532
-
-
Paddon, C.J.1
Westfall, P.J.2
Pitera, D.J.3
Benjamin, K.4
Fisher, K.5
McPhee, D.6
Leavell, M.D.7
Tai, A.8
Main, A.9
Eng, D.10
Polichuk, D.R.11
Teoh, K.H.12
Reed, D.W.13
Treynor, T.14
Lenihan, J.15
Fleck, M.16
Bajad, S.17
Dang, G.18
Dengrove, D.19
Diola, D.20
Dorin, G.21
Ellens, K.W.22
Fickes, S.23
Galazzo, J.24
Gaucher, S.P.25
Geistlinger, T.26
Henry, R.27
Hepp, M.28
Horning, T.29
Iqbal, T.30
Jiang, H.31
Kizer, L.32
Lieu, B.33
Melis, D.34
Moss, N.35
Regentin, R.36
Secrest, S.37
Tsuruta, H.38
Vazquez, R.39
Westblade, L.F.40
Xu, L.41
Yu, M.42
Zhang, Y.43
Zhao, L.44
Lievense, J.45
Covello, P.S.46
Keasling, J.D.47
Reiling, K.K.48
Renninger, N.S.49
Newman, J.D.50
more..
-
77
-
-
85014051792
-
-
Synthetic biology's malaria promises could backfire [Online], accessed January 5, 2015
-
Marris, C. SciDeveNet. Synthetic biology's malaria promises could backfire [Online], 2013. http://www.scidev.net/global/biotechnology/opinion/synthetic-biology-smalaria- promises-could-backfire.html (accessed January 5, 2015).
-
(2013)
SciDeveNet
-
-
Marris, C.1
-
78
-
-
66349139329
-
New Microbial Fuels: A Biotech Perspective
-
Rude, M. A.; Schirmer, A. New Microbial Fuels: A Biotech Perspective. Curr. Opin. Microbiol. 2009, 12(3), 274-81.
-
(2009)
Curr. Opin. Microbiol.
, vol.12
, Issue.3
, pp. 274-281
-
-
Rude, M.A.1
Schirmer, A.2
-
79
-
-
84889944444
-
-
U.S. Pat. Appl. 0058532 A1
-
Buelter, T.; Meinhold, P.; Feldman, R.; Hawkins, A.; Bastian, S.; Arnold, F. H.; Urano, J. Engineered microorganisms capable of producing target compounds under anaerobic conditions. U.S. Pat. Appl. 0058532 A1, 2012
-
(2012)
Engineered microorganisms capable of producing target compounds under anaerobic conditions
-
-
Buelter, T.1
Meinhold, P.2
Feldman, R.3
Hawkins, A.4
Bastian, S.5
Arnold, F.H.6
Urano, J.7
-
80
-
-
53549123678
-
-
U.S. Pat. Appl. 0313206 A1
-
Donaldson, G. K.; Eliot, A.; Flint, D.; Maggio-Hall, A.; Nagarajan, V. Fermentative production of four carbon alcohols. U.S. Pat. Appl. 0313206 A1, 2007.
-
(2007)
Fermentative production of four carbon alcohols
-
-
Donaldson, G.K.1
Eliot, A.2
Flint, D.3
Maggio-Hall, A.4
Nagarajan, V.5
-
81
-
-
84864186953
-
Metabolic engineering of Saccharomyces cerevisiae: a key cell factory platform for future biorefineries
-
Hong, K. K.; Nielsen, J. Metabolic engineering of Saccharomyces cerevisiae: a key cell factory platform for future biorefineries. Cell. Mol. Life Sci. 2012, 69(16), 2671-90.
-
(2012)
Cell. Mol. Life Sci.
, vol.69
, Issue.16
, pp. 2671-2690
-
-
Hong, K.K.1
Nielsen, J.2
-
82
-
-
53549123678
-
-
U.S. U.S. Pat. Appl. 0092957 A1
-
Donaldson, G. K.; Eliot, A.; Flint, D.; Maggio-Hall, A.; Nagarajan, V. Fermentative production of four carbon alcohols. U.S. U.S. Pat. Appl. 0092957 A1, 2007.
-
(2007)
Fermentative production of four carbon alcohols
-
-
Donaldson, G.K.1
Eliot, A.2
Flint, D.3
Maggio-Hall, A.4
Nagarajan, V.5
-
83
-
-
84864249571
-
-
U.S. Patent 8,530,226 B2, September 10
-
Festel, G.; Boles, E.; Weber, C.; Brat, D. Fermentative production of isobutanol with yeast. U.S. Patent 8,530,226 B2, September 10, 2013.
-
(2013)
Fermentative production of isobutanol with yeast
-
-
Festel, G.1
Boles, E.2
Weber, C.3
Brat, D.4
-
84
-
-
76949092903
-
Biodiesel and renewable diesel: A comparison
-
Knothe, G. Biodiesel and renewable diesel: A comparison. Prog. Energy Combust. Sci. 2010, 36, 364-73.
-
(2010)
Prog. Energy Combust. Sci.
, vol.36
, pp. 364-373
-
-
Knothe, G.1
-
85
-
-
78650518299
-
-
U.S. Patent 8,889,401, November 18
-
Trimbur, D.; Im, C.-S.; Dillon, H.; Day, A.; Franklin, S.; Coragliotti, A. Production of oil in microorganisms. U.S. Patent 8,889,401, November 18, 2014.
-
(2014)
Production of oil in microorganisms
-
-
Trimbur, D.1
Im, C.-S.2
Dillon, H.3
Day, A.4
Franklin, S.5
Coragliotti, A.6
-
86
-
-
85014042496
-
-
Presented at Workshop on the Industrialization of Biology, May 28
-
Burk, M. Personal Comments. Presented at Workshop on the Industrialization of Biology, May 28, 2014.
-
(2014)
Personal Comments
-
-
Burk, M.1
-
87
-
-
79959374585
-
Metabolic engineering of Escherichia coli for direct production of 1,4-butanediol
-
Yim, H.; Haselbeck, R.; Niu, W.; Pujol-Baxley, C.; Burgard, A.; Boldt, J.; Khandurina, J.; Trawick, J. D.; Osterhout, R. E.; Stephen, R.; Estadilla, J.; Teisan, S.; Schreyer, H. B.; Andrae, S.; Yang, T. H.; Lee, S. Y.; Burk, M. J.; Van Dien, S. Metabolic engineering of Escherichia coli for direct production of 1,4-butanediol. Nat. Chem. Biol. 2011, 7(7), 445-52
-
(2011)
Nat. Chem. Biol.
, vol.7
, Issue.7
, pp. 445-452
-
-
Yim, H.1
Haselbeck, R.2
Niu, W.3
Pujol-Baxley, C.4
Burgard, A.5
Boldt, J.6
Khandurina, J.7
Trawick, J.D.8
Osterhout, R.E.9
Stephen, R.10
Estadilla, J.11
Teisan, S.12
Schreyer, H.B.13
Andrae, S.14
Yang, T.H.15
Lee, S.Y.16
Burk, M.J.17
Van Dien, S.18
-
88
-
-
79955804234
-
Sustainable production of industrial chemicals from sugars
-
Burk, M. J. Sustainable production of industrial chemicals from sugars. Int. Sugar J. 2010, 112(1333), 30.
-
(2010)
Int. Sugar J.
, vol.112
, Issue.1333
, pp. 30
-
-
Burk, M.J.1
-
90
-
-
84887632949
-
Communicating science in social settings
-
Scheufele, D. A. Communicating science in social settings. Proc. Natl. Acad. Sci. U. S. A. 2013, 110(Supplement 3), 14040-7.
-
(2013)
Proc. Natl. Acad. Sci. U. S. A.
, vol.110
, pp. 14040-14047
-
-
Scheufele, D.A.1
-
91
-
-
84907446194
-
Final NIH Genomic Data Sharing Policy
-
NIH (National Institutes of Health). Final NIH Genomic Data Sharing Policy. Fed Regist. 2014, 79(167), 51345-54.
-
(2014)
Fed Regist
, vol.79
, Issue.167
, pp. 51345-51354
-
-
-
93
-
-
0042844744
-
Natural products as sources of new drugs over the period 1981-2002
-
Newman, D. J.; Cragg, G. M.; Snader, K. M. Natural products as sources of new drugs over the period 1981-2002. J. Nat. Prod. 2003, 66(7), 1022-37.
-
(2003)
J. Nat. Prod.
, vol.66
, Issue.7
, pp. 1022-1037
-
-
Newman, D.J.1
Cragg, G.M.2
Snader, K.M.3
-
94
-
-
0344609866
-
Shikimic acid and quinic acid: Replacing isolation from plant aources with recombinant microbial biocatalysis
-
Draths, K. M.; Knop, D. R.; Frost, J. W. Shikimic acid and quinic acid: Replacing isolation from plant aources with recombinant microbial biocatalysis. J. Am. Chem. Soc. 1999, 121(7), 1603-4
-
(1999)
J. Am. Chem. Soc.
, vol.121
, Issue.7
, pp. 1603-1604
-
-
Draths, K.M.1
Knop, D.R.2
Frost, J.W.3
-
95
-
-
1642457254
-
Metabolic engineering for microbial production of shikimic acid
-
Krämer, M.; Bongaerts, J.; Bovenberg, R.; Kremer, S.; Müller, U.; Orf, S.; Wubbolts, M.; Raeven, L. Metabolic engineering for microbial production of shikimic acid. Metab. Eng. 2003, 5(4), 277-83.
-
(2003)
Metab. Eng.
, vol.5
, Issue.4
, pp. 277-283
-
-
Krämer, M.1
Bongaerts, J.2
Bovenberg, R.3
Kremer, S.4
Müller, U.5
Orf, S.6
Wubbolts, M.7
Raeven, L.8
-
96
-
-
33846197938
-
Biocatalysis for pharmaceutical intermediates: the future is now
-
Pollard, D. J.; Woodley, J. M. Biocatalysis for pharmaceutical intermediates: the future is now. Trends in Biotechnol. 2007, 25(2), 66-73
-
(2007)
Trends in Biotechnol.
, vol.25
, Issue.2
, pp. 66-73
-
-
Pollard, D.J.1
Woodley, J.M.2
-
97
-
-
84856717640
-
Expanding the organic toolbox: A guide to integrating biocatalysis in synthesis
-
Clouthier, C. M.; Pelletier, J. N. Expanding the organic toolbox: A guide to integrating biocatalysis in synthesis. Chem. Soc. Rev. 2012, 41(4), 1585-605.
-
(2012)
Chem. Soc. Rev.
, vol.41
, Issue.4
, pp. 1585-1605
-
-
Clouthier, C.M.1
Pelletier, J.N.2
-
98
-
-
77954797329
-
Biocatalytic Asymmetric Synthesis of Chiral Amines from Ketones Applied to Sitagliptin Manufacture
-
Savile, C. K.; Janey, J. M.; Mundorff, E. C.; Moore, J. C.; Tam, S.; Jarvis, W. R.; Colbeck, J. C.; Krebber, A.; Fleitz, F. J.; Brands, J.; Devine, P. N.; Huisman, G. W.; Hughes, G. J. Biocatalytic Asymmetric Synthesis of Chiral Amines from Ketones Applied to Sitagliptin Manufacture. Science 2010, 329(5989), 305-9.
-
(2010)
Science
, vol.329
, Issue.5989
, pp. 305-309
-
-
Savile, C.K.1
Janey, J.M.2
Mundorff, E.C.3
Moore, J.C.4
Tam, S.5
Jarvis, W.R.6
Colbeck, J.C.7
Krebber, A.8
Fleitz, F.J.9
Brands, J.10
Devine, P.N.11
Huisman, G.W.12
Hughes, G.J.13
-
99
-
-
34848848499
-
Fluorine in pharmaceuticals: Looking beyond intuition
-
Müller, K.; Faeh, C.; Diederich, F. Fluorine in pharmaceuticals: Looking beyond intuition. Science 2007, 317(5846), 1881-6
-
(2007)
Science
, vol.317
, Issue.5846
, pp. 1881-1886
-
-
Müller, K.1
Faeh, C.2
Diederich, F.3
-
100
-
-
38149070200
-
Fluorine in medicinal chemistry
-
Purser, S.; Moore, P. R.; Swallow, S.; Gouverneur, V. Fluorine in medicinal chemistry. Chem. Soc. Rev. 2008, 37(2), 320-30
-
(2008)
Chem. Soc. Rev.
, vol.37
, Issue.2
, pp. 320-330
-
-
Purser, S.1
Moore, P.R.2
Swallow, S.3
Gouverneur, V.4
-
101
-
-
77950455094
-
Engineering fluorometabolite production:Fluorinase expression in Salinispora tropica yields fluorosalinosporamide
-
Eustaquio, A. S.; O'Hagan, D.; Moore, B. S. Engineering fluorometabolite production:Fluorinase expression in Salinispora tropica yields fluorosalinosporamide. J. Nat. Prod. 2010, 73(3), 378-82
-
(2010)
J. Nat. Prod.
, vol.73
, Issue.3
, pp. 378-382
-
-
Eustaquio, A.S.1
O'Hagan, D.2
Moore, B.S.3
-
102
-
-
78549294465
-
Integrating carbonhalogen bond formation into medicinal plant metabolism
-
Runguphan, W.; Qu, X.; O'Connor, S. E. Integrating carbonhalogen bond formation into medicinal plant metabolism. Nature 2010, 468(7322), 461-4
-
(2010)
Nature
, vol.468
, Issue.7322
, pp. 461-464
-
-
Runguphan, W.1
Qu, X.2
O'Connor, S.E.3
-
103
-
-
84883484875
-
Expanding the Fluorine Chemistry of Living Systems Using Engineered Polyketide Synthase Pathways
-
Walker, M. C.; Thuronyi, B. W.; Charkoudian, L. K.; Lowry, B.; Khosla, C.; Chang, M. C., Expanding the Fluorine Chemistry of Living Systems Using Engineered Polyketide Synthase Pathways. Science 2013, 341(6150), 1089-94.
-
(2013)
Science
, vol.341
, Issue.6150
, pp. 1089-1094
-
-
Walker, M.C.1
Thuronyi, B.W.2
Charkoudian, L.K.3
Lowry, B.4
Khosla, C.5
Chang, M.C.6
-
104
-
-
84872495336
-
Olefin cyclopropanation via carbene transfer catalyzed by engineered cytochrome P450 enzymes
-
Coelho, P. S.; Brustad, E. M.; Kannan, A.; Arnold, F. H. Olefin cyclopropanation via carbene transfer catalyzed by engineered cytochrome P450 enzymes. Science 2013, 339(6117), 307-10
-
(2013)
Science
, vol.339
, Issue.6117
, pp. 307-310
-
-
Coelho, P.S.1
Brustad, E.M.2
Kannan, A.3
Arnold, F.H.4
-
105
-
-
84883040115
-
Enantioselective intramolecular C-H amination catalyzed by engineered cytochrome P450 enzymes in vitro and in vivo
-
McIntosh, J. A.; Coelho, P. S.; Farwell, C. C.; Wang, Z. J.; Lewis, J. C.; Brown, T. R.; Arnold, F. H. Enantioselective intramolecular C-H amination catalyzed by engineered cytochrome P450 enzymes in vitro and in vivo. Angew. Chem., Int. Ed. 2013, 52(35), 9309-12.
-
(2013)
Angew. Chem., Int. Ed.
, vol.52
, Issue.35
, pp. 9309-9312
-
-
McIntosh, J.A.1
Coelho, P.S.2
Farwell, C.C.3
Wang, Z.J.4
Lewis, J.C.5
Brown, T.R.6
Arnold, F.H.7
-
106
-
-
0018536719
-
Purification and Properties of Strictosidine Synthase, the Key Enzyme in Indole Alkaloid Formation
-
Treimer, J. F.; Zenk, M. H. Purification and Properties of Strictosidine Synthase, the Key Enzyme in Indole Alkaloid Formation. Eur. J. Biochem. 1979, 101(1), 225-33.
-
(1979)
Eur. J. Biochem.
, vol.101
, Issue.1
, pp. 225-233
-
-
Treimer, J.F.1
Zenk, M.H.2
-
107
-
-
79955642774
-
Enzyme-catalysed [4+2] cycloaddition is a key step in the biosynthesis of spinosyn A
-
Kim, H. J.; Ruszczycky, M. W.; Choi, S. H.; Liu, Y. N.; Liu, H. W. Enzyme-catalysed [4+2] cycloaddition is a key step in the biosynthesis of spinosyn A. Nature 2011, 473(7345), 109-12.
-
(2011)
Nature
, vol.473
, Issue.7345
, pp. 109-112
-
-
Kim, H.J.1
Ruszczycky, M.W.2
Choi, S.H.3
Liu, Y.N.4
Liu, H.W.5
-
108
-
-
84906838061
-
-
International Renewable Energy Agency and Energy Technology Systems Analysis Programme; IREA: Abu Dhabi, UAE
-
IREA (International Renewable Energy Agency). Production of bio-ethylene (Technology Brief I13); International Renewable Energy Agency and Energy Technology Systems Analysis Programme; IREA: Abu Dhabi, UAE, 2013.
-
(2013)
Production of bio-ethylene (Technology Brief I13)
-
-
-
109
-
-
79959374585
-
Metabolic Engineering of Escherichia coli for Direct Production of 1,4-Butanediol
-
Yim, H.; Haselbeck, R.; Niu, W.; Pujol-Baxley, C.; Burgard, A.; Boldt, J.; Khandurina, J.; Trawick, J. D.; Osterhout, R. E.; Stephen, R.; Estadilla, J.; Teisan, S.; Schreyer, H. B.; Andrae, S.; Yang, T. H.; Lee, S. Y.; Burk, M. J.; Van Dien, S. Metabolic Engineering of Escherichia coli for Direct Production of 1,4-Butanediol. Nat. Chem. Biol. 2011, 7(7), 445-52.
-
(2011)
Nat. Chem. Biol.
, vol.7
, Issue.7
, pp. 445-452
-
-
Yim, H.1
Haselbeck, R.2
Niu, W.3
Pujol-Baxley, C.4
Burgard, A.5
Boldt, J.6
Khandurina, J.7
Trawick, J.D.8
Osterhout, R.E.9
Stephen, R.10
Estadilla, J.11
Teisan, S.12
Schreyer, H.B.13
Andrae, S.14
Yang, T.H.15
Lee, S.Y.16
Burk, M.J.17
Van Dien, S.18
-
110
-
-
85050580661
-
Hunting for Biobased Acrylic Acid
-
Tullo, A. H. Hunting for Biobased Acrylic Acid. Chem. Eng. News 2013, 91(46), 18-9.
-
(2013)
Chem. Eng. News
, vol.91
, Issue.46
, pp. 18-19
-
-
Tullo, A.H.1
-
111
-
-
77955226866
-
An overview of the recent developments in polylactide (PLA) research
-
Madhavan Nampoothiri, K.; Nair, N. R.; John, R. P. An overview of the recent developments in polylactide (PLA) research. Bioresour. Technol. 2010, 101(22), 8493-501.
-
(2010)
Bioresour. Technol.
, vol.101
, Issue.22
, pp. 8493-8501
-
-
Madhavan Nampoothiri, K.1
Nair, N.R.2
John, R.P.3
-
112
-
-
0025226099
-
Occurrence, Metabolism, Metabolic Role, and Industrial Uses of Bacterial Polyhydroxyalkanoates
-
Anderson, A. J.; Dawes, E. A. Occurrence, Metabolism, Metabolic Role, and Industrial Uses of Bacterial Polyhydroxyalkanoates. Microbiol. Rev. 1990, 54(4), 450-72.
-
(1990)
Microbiol. Rev.
, vol.54
, Issue.4
, pp. 450-472
-
-
Anderson, A.J.1
Dawes, E.A.2
-
113
-
-
0141765883
-
Fabrication of Novel Biomaterials through Molecular Self-Assembly
-
Zhang, S., Fabrication of Novel Biomaterials through Molecular Self-Assembly. Nat. Biotechnol. 2003, 21(10), 1171-8.
-
(2003)
Nat. Biotechnol.
, vol.21
, Issue.10
, pp. 1171-1178
-
-
Zhang, S.1
-
114
-
-
0015237389
-
Ribosome-catalyzed polyester formation
-
Fahnestock, S.; Rich, A. Ribosome-catalyzed polyester formation. Science 1971, 173(3994), 340-3
-
(1971)
Science
, vol.173
, Issue.3994
, pp. 340-343
-
-
Fahnestock, S.1
Rich, A.2
-
115
-
-
0346095498
-
Virus-based toolkit for the directed synthesis of magnetic and semiconducting nanowires
-
Mao, C.; Solis, D. J.; Reiss, B. D.; Kottmann, S. T.; Sweeney, R. Y.; Hayhurst, A.; Georgiou, G.; Iverson, B.; Belcher, A. M. Virus-based toolkit for the directed synthesis of magnetic and semiconducting nanowires. Science 2004, 303(5655), 213-7
-
(2004)
Science
, vol.303
, Issue.5655
, pp. 213-217
-
-
Mao, C.1
Solis, D.J.2
Reiss, B.D.3
Kottmann, S.T.4
Sweeney, R.Y.5
Hayhurst, A.6
Georgiou, G.7
Iverson, B.8
Belcher, A.M.9
-
116
-
-
37149000703
-
Synthesis of polyester by means of genetic code reprogramming
-
Ohta, A.; Murakami, H.; Higashimura, E.; Suga, H. Synthesis of polyester by means of genetic code reprogramming. Chemistry & Biology 2007, 14(12), 1315-22.
-
(2007)
Chemistry & Biology
, vol.14
, Issue.12
, pp. 1315-1322
-
-
Ohta, A.1
Murakami, H.2
Higashimura, E.3
Suga, H.4
-
117
-
-
0021796043
-
Interactions between acidic proteins and crystals: Stereochemical requirements in biomineralization
-
Addadi, L.; Weiner, S. Interactions between acidic proteins and crystals: Stereochemical requirements in biomineralization. Proc. Natl. Acad. Sci. U. S. A. 1985, 82(12), 4110-4
-
(1985)
Proc. Natl. Acad. Sci. U. S. A.
, vol.82
, Issue.12
, pp. 4110-4114
-
-
Addadi, L.1
Weiner, S.2
-
118
-
-
0027790336
-
Crystallization at Inorganic-organic Interfaces:Biominerals and Biomimetic Synthesis
-
Mann, S.; Archibald, D. D.; Didymus, J. M.; Douglas, T.; Heywood, B. R.; Meldrum, F. C.; Reeves, N. J. Crystallization at Inorganic-organic Interfaces:Biominerals and Biomimetic Synthesis. Science 1993, 261(5126), 1286-92
-
(1993)
Science
, vol.261
, Issue.5126
, pp. 1286-1292
-
-
Mann, S.1
Archibald, D.D.2
Didymus, J.M.3
Douglas, T.4
Heywood, B.R.5
Meldrum, F.C.6
Reeves, N.J.7
-
119
-
-
0029669273
-
Control of crystal phase switching and orientation by soluble mollusc-shell proteins
-
Belcher, A. M.; Wu, X. H.; Christensen, R. J.; Hansma, P. K.; Stucky, G. D.; Morse, D. E. Control of crystal phase switching and orientation by soluble mollusc-shell proteins. Nature 1996, 381(6577), 56-8
-
(1996)
Nature
, vol.381
, Issue.6577
, pp. 56-58
-
-
Belcher, A.M.1
Wu, X.H.2
Christensen, R.J.3
Hansma, P.K.4
Stucky, G.D.5
Morse, D.E.6
-
120
-
-
0034604514
-
Aggregation-Based Crystal Growth and Microstructure Development in Natural Iron Oxyhydroxide Biomineralization Products
-
Banfield, J. F.; Welch, S. A.; Zhang, H.; Ebert, T. T.; Penn, R. L. Aggregation-Based Crystal Growth and Microstructure Development in Natural Iron Oxyhydroxide Biomineralization Products. Science 2000, 289(5480), 751-4
-
(2000)
Science
, vol.289
, Issue.5480
, pp. 751-754
-
-
Banfield, J.F.1
Welch, S.A.2
Zhang, H.3
Ebert, T.T.4
Penn, R.L.5
-
121
-
-
0041357157
-
Fibre-optical features of a glass sponge
-
Sundar, V. C.; Yablon, A. D.; Grazul, J. L.; Ilan, M.; Aizenberg, J. Fibre-optical features of a glass sponge. Nature 2003, 424(6951), 899-900.
-
(2003)
Nature
, vol.424
, Issue.6951
, pp. 899-900
-
-
Sundar, V.C.1
Yablon, A.D.2
Grazul, J.L.3
Ilan, M.4
Aizenberg, J.5
-
123
-
-
85014055390
-
-
accessed July 25, 2014
-
U.S. Energy Information Administration. U.S. Number of Operable Refineries as of January 1. http://www.eia.gov/dnav/pet/hist/LeafHandler.ashx?n=PET&s=8_ NA_8O0_NUS_C&f=A (accessed July 25, 2014).
-
U.S. Number of Operable Refineries as of January 1
-
-
-
125
-
-
33746292270
-
Potential for biofuels for transport in developing countries
-
Kojima, M.; Johnson, T. Potential for biofuels for transport in developing countries. ESMAP Knowledge Exchange Series 2005, 4, 1-4.
-
(2005)
ESMAP Knowledge Exchange Series
, vol.4
, pp. 1-4
-
-
Kojima, M.1
Johnson, T.2
-
127
-
-
84884246828
-
Converting Lignocellulosic Biomass to Low Cost Fermentable Sugars
-
Springer: Berlin
-
Fang, Z. Converting Lignocellulosic Biomass to Low Cost Fermentable Sugars. In Pretreatment Techniques for Biofuels and Biorefineries; Springer: Berlin, 2013; pp 133-150
-
(2013)
Pretreatment Techniques for Biofuels and Biorefineries;
, pp. 133-150
-
-
Fang, Z.1
-
128
-
-
1642436434
-
Supercritical and near-critical CO 2 in green chemical synthesis and processing
-
Beckman, E. J. Supercritical and near-critical CO 2 in green chemical synthesis and processing. J. Supercrit. Fluids 2004, 28(2), 121-91.
-
(2004)
J. Supercrit. Fluids
, vol.28
, Issue.2
, pp. 121-191
-
-
Beckman, E.J.1
-
129
-
-
84878656888
-
From Protein Engineering to Immobilization:Promising Strategies for the Upgrade of Industrial Enzymes
-
Singh, R. K.; Tiwari, M. K.; Singh, R.; Lee, J.-K. From Protein Engineering to Immobilization:Promising Strategies for the Upgrade of Industrial Enzymes. Int. J. Mol. Sci. 2013, 14(1), 1232-77.
-
(2013)
Int. J. Mol. Sci.
, vol.14
, Issue.1
, pp. 1232-1277
-
-
Singh, R.K.1
Tiwari, M.K.2
Singh, R.3
Lee, J.-K.4
-
130
-
-
56649123318
-
Cell-free protein synthesis: applications in proteomics and biotechnology
-
He, M. Cell-free protein synthesis: applications in proteomics and biotechnology. New Biotechnol. 2008, 25(2-3), 126-32.
-
(2008)
New Biotechnol.
, vol.25
, Issue.2-3
, pp. 126-132
-
-
He, M.1
-
131
-
-
84882379836
-
New biotechnology paradigm: cell-free biosystems for biomanufacturing
-
Rollin, J. A.; Tam, T. K.; Zhang, Y. H. P. New biotechnology paradigm: cell-free biosystems for biomanufacturing. Green Chem. 2013, 15(7), 1708-19.
-
(2013)
Green Chem.
, vol.15
, Issue.7
, pp. 1708-1719
-
-
Rollin, J.A.1
Tam, T.K.2
Zhang, Y.H.P.3
-
132
-
-
33749133230
-
Metabolic Flux Distributions in Corynebacterium Glutamicum During Growth and Lysine Overproduction
-
Vallino, J. J.; Stephanopoulos, G. Metabolic Flux Distributions in Corynebacterium Glutamicum During Growth and Lysine Overproduction. Biotechnology and Bioengineering 2000, 67(6), 872-85.
-
(2000)
Biotechnology and Bioengineering
, vol.67
, Issue.6
, pp. 872-885
-
-
Vallino, J.J.1
Stephanopoulos, G.2
-
133
-
-
0025882349
-
PROSITE: A Dictionary of Sites and Patterns in Proteins
-
Bairoch, A. PROSITE: A Dictionary of Sites and Patterns in Proteins. Nucleic Acids Res. 1991, 19(Supplemental), 2241-5
-
(1991)
Nucleic Acids Res.
, vol.19
, pp. 2241-2245
-
-
Bairoch, A.1
-
134
-
-
33644876022
-
The PROSITE database
-
Hulo, N.; Bairoch, A.; Bulliard, V.; Cerutti, L.; De Castro, E.; Langendijk-Genevaux, P. S.; Pagni, M.; Sigrist, C. J. A. The PROSITE database. Nucleic Acids Res. 2006, 34(Supplemental), D227-30.
-
(2006)
Nucleic Acids Res.
, vol.34
, pp. D227-D230
-
-
Hulo, N.1
Bairoch, A.2
Bulliard, V.3
Cerutti, L.4
De Castro, E.5
Langendijk-Genevaux, P.S.6
Pagni, M.7
Sigrist, C.J.A.8
-
135
-
-
0030825309
-
COBRA: A Sensitive and Quantitative DNA Methylation Assay
-
Xiong, Z.; Laird, P. W. COBRA: A Sensitive and Quantitative DNA Methylation Assay. Nucleic Acids Res. 1997, 25(12), 2532-4.
-
(1997)
Nucleic Acids Res.
, vol.25
, Issue.12
, pp. 2532-2534
-
-
Xiong, Z.1
Laird, P.W.2
-
136
-
-
84859327697
-
DNA Assembly Method Standardization for Synthetic Biomolecular Circuits and Systems
-
Koeppl, H.; Setti, G.; di Bernardo, M.; Densmore, D., Eds. Springer: New York
-
Hillson, N. DNA Assembly Method Standardization for Synthetic Biomolecular Circuits and Systems. In Design and Analysis of Biomolecular Circuits, Koeppl, H.; Setti, G.; di Bernardo, M.; Densmore, D., Eds. Springer: New York, 2011; pp 295-314.
-
(2011)
Design and Analysis of Biomolecular Circuits
, pp. 295-314
-
-
Hillson, N.1
-
137
-
-
84948665476
-
Digital Imaging and Communications in Medicine
-
Deserno, T. M., Ed. Springer: Berlin
-
Onken, M.; Eichelberg, M.; Riesmeier, J.; Jensch, P. Digital Imaging and Communications in Medicine. In Biomedical Image Processing, Deserno, T. M., Ed. Springer: Berlin, 2011; pp 427-54.
-
(2011)
Biomedical Image Processing
, pp. 427-454
-
-
Onken, M.1
Eichelberg, M.2
Riesmeier, J.3
Jensch, P.4
-
138
-
-
46949091517
-
Refinement and standardization of synthetic biological parts and devices
-
Canton, B.; Labno, A.; Endy, D. Refinement and standardization of synthetic biological parts and devices. Nat. Biotechnol. 2008, 26(7), 787-93
-
(2008)
Nat. Biotechnol.
, vol.26
, Issue.7
, pp. 787-793
-
-
Canton, B.1
Labno, A.2
Endy, D.3
-
139
-
-
34547756879
-
The iGEM competition: building with biology
-
1.2
-
Brown, J. The iGEM competition: building with biology. Synthetic Biology, IET 2007, 1(1.2), 3-6.
-
(2007)
Synthetic Biology, IET
, vol.1
, pp. 3-6
-
-
Brown, J.1
-
140
-
-
84867488931
-
Design, implementation and practice of JBEI-ICE: an open source biological part registry platform and tools
-
Ham, T. S.; Dmytriv, Z.; Plahar, H.; Chen, J.; Hillson, N. J.; Keasling, J. D. Design, implementation and practice of JBEI-ICE: an open source biological part registry platform and tools. Nucleic Acids Res. 2012, 40(18), e141.
-
(2012)
Nucleic Acids Res.
, vol.40
, Issue.18
, pp. e141
-
-
Ham, T.S.1
Dmytriv, Z.2
Plahar, H.3
Chen, J.4
Hillson, N.J.5
Keasling, J.D.6
-
141
-
-
77951969603
-
Standard virtual biological parts: a repository of modular modeling components for synthetic biology
-
Cooling, M. T.; Rouilly, V.; Misirli, G.; Lawson, J.; Yu, T.; Hallinan, J.; Wipat, A. Standard virtual biological parts: a repository of modular modeling components for synthetic biology. Bioinformatics 2010, 26(7), 925-31.
-
(2010)
Bioinformatics
, vol.26
, Issue.7
, pp. 925-931
-
-
Cooling, M.T.1
Rouilly, V.2
Misirli, G.3
Lawson, J.4
Yu, T.5
Hallinan, J.6
Wipat, A.7
-
142
-
-
84891766371
-
DNASU plasmid and PSI:Biology-Materials repositories: resources to accelerate biological research
-
Seiler, C. Y.; Park, J. G.; Sharma, A.; Hunter, P.; Surapaneni, P.; Sedillo, C.; Field, J.; Algar, R.; Price, A.; Steel, J.; Throop, A.; Fiacco, M.; LaBaer, J. DNASU plasmid and PSI:Biology-Materials repositories: resources to accelerate biological research. Nucleic Acids Res. 2013, 42(Database Issue), D1253-60.
-
(2013)
Nucleic Acids Res.
, vol.42
, Issue.DATABASE ISSUE
, pp. D1253-D1260
-
-
Seiler, C.Y.1
Park, J.G.2
Sharma, A.3
Hunter, P.4
Surapaneni, P.5
Sedillo, C.6
Field, J.7
Algar, R.8
Price, A.9
Steel, J.10
Throop, A.11
Fiacco, M.12
LaBaer, J.13
-
143
-
-
84859638111
-
Addgene provides an open forum for plasmid sharing
-
Herscovitch, M.; Perkins, E.; Baltus, A.; Fan, M. Addgene provides an open forum for plasmid sharing. Nat. Biotechnol. 2012, 30(4), 316-7.
-
(2012)
Nat. Biotechnol.
, vol.30
, Issue.4
, pp. 316-317
-
-
Herscovitch, M.1
Perkins, E.2
Baltus, A.3
Fan, M.4
-
144
-
-
3042810286
-
Biosynthesis of isoprenoids via the non-mevalonate pathway
-
Eisenreich, W.; Bacher, A.; Arigoni, D.; Rohdich, F., Biosynthesis of isoprenoids via the non-mevalonate pathway. Cell. Mol. Life Sci. 2004, 61(12), 1401-26
-
(2004)
Cell. Mol. Life Sci.
, vol.61
, Issue.12
, pp. 1401-1426
-
-
Eisenreich, W.1
Bacher, A.2
Arigoni, D.3
Rohdich, F.4
-
145
-
-
0033213706
-
The discovery of a mevalonate-independent pathway for isoprenoid biosynthesis in bacteria, algae and higher plants
-
Rohmer, M. The discovery of a mevalonate-independent pathway for isoprenoid biosynthesis in bacteria, algae and higher plants. Natural Products Reports 1999, 16(5), 565-74.
-
(1999)
Natural Products Reports
, vol.16
, Issue.5
, pp. 565-574
-
-
Rohmer, M.1
-
146
-
-
79952460925
-
Oxidative versus reductive succinic acid production in the yeast Saccharomyces cerevisiae
-
Raab, A. M.; Lang, C. Oxidative versus reductive succinic acid production in the yeast Saccharomyces cerevisiae. Bioengineered Bugs 2011, 2(2), 120-3.
-
(2011)
Bioengineered Bugs
, vol.2
, Issue.2
, pp. 120-123
-
-
Raab, A.M.1
Lang, C.2
-
147
-
-
84895071963
-
EC-BLAST:a tool to automatically search and compare enzyme reactions
-
Rahman, S. A.; Cuesta, S. M.; Furnham, N.; Holliday, G. L.; Thornton, J. M. EC-BLAST:a tool to automatically search and compare enzyme reactions. Nat. Methods 2014, 11(2), 171-4.
-
(2014)
Nat. Methods
, vol.11
, Issue.2
, pp. 171-174
-
-
Rahman, S.A.1
Cuesta, S.M.2
Furnham, N.3
Holliday, G.L.4
Thornton, J.M.5
-
148
-
-
0030801002
-
Gapped BLAST and PSI-BLAST: a new generation of protein database search programs
-
Altschul, S. F.; Madden, T. L.; Schäffer, A. A.; Zhang, J.; Zhang, Z.; Miller, W.; Lipman, D. J. Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res. 1997, 25(17), 3389-402.
-
(1997)
Nucleic Acids Res.
, vol.25
, Issue.17
, pp. 3389-3402
-
-
Altschul, S.F.1
Madden, T.L.2
Schäffer, A.A.3
Zhang, J.4
Zhang, Z.5
Miller, W.6
Lipman, D.J.7
-
149
-
-
84902078914
-
From sequence to enzyme mechanism using multi-label machine learning
-
De Ferrari, L.; Mitchell, J. B. From sequence to enzyme mechanism using multi-label machine learning. BMC Bioinformatics 2014, 15, 150.
-
(2014)
BMC Bioinformatics
, vol.15
, pp. 150
-
-
De Ferrari, L.1
Mitchell, J.B.2
-
150
-
-
79955534060
-
A system for the continuous directed evolution of biomolecules
-
Esvelt, K. M.; Carlson, J. C.; Liu, D. R. A system for the continuous directed evolution of biomolecules. Nature 2011, 472(7344), 499-503.
-
(2011)
Nature
, vol.472
, Issue.7344
, pp. 499-503
-
-
Esvelt, K.M.1
Carlson, J.C.2
Liu, D.R.3
-
151
-
-
33947095042
-
Improving catalytic function by ProSAR-driven enzyme evolu- tion
-
Fox, R. J.; Davis, S. C.; Mundorff, E. C.; Newman, L. M.; Gavrilovic, V.; Ma, S. K.; Chung, L. M.; Ching, C.; Tam, S.; Muley, S.; Grate, J.; Gruber, J.; Whitman, J. C.; Sheldon, R. A.; Huisman, G. W. Improving catalytic function by ProSAR-driven enzyme evolu- tion. Nature Biotechnol. 2007, 25(3), 338-44
-
(2007)
Nature Biotechnol.
, vol.25
, Issue.3
, pp. 338-344
-
-
Fox, R.J.1
Davis, S.C.2
Mundorff, E.C.3
Newman, L.M.4
Gavrilovic, V.5
Ma, S.K.6
Chung, L.M.7
Ching, C.8
Tam, S.9
Muley, S.10
Grate, J.11
Gruber, J.12
Whitman, J.C.13
Sheldon, R.A.14
Huisman, G.W.15
-
152
-
-
55549108089
-
Engineered enzymes for chemical production
-
Luetz, S.; Giver, L.; Lalonde, J. Engineered enzymes for chemical production. Biotechnology and Bioengineering 2008, 101(4), 647-53.
-
(2008)
Biotechnology and Bioengineering
, vol.101
, Issue.4
, pp. 647-653
-
-
Luetz, S.1
Giver, L.2
Lalonde, J.3
-
153
-
-
77957575104
-
Recombinant organisms for production of industrial products
-
Adrio, J.-L.; Demain, A. L. Recombinant organisms for production of industrial products. Bioengineered Bugs 2010, 1(2), 116-131.
-
(2010)
Bioengineered Bugs
, vol.1
, Issue.2
, pp. 116-131
-
-
Adrio, J.-L.1
Demain, A.L.2
-
154
-
-
84893230222
-
Evolution of CRISPR RNA recognition and processing by Cas6 endonucleases
-
Niewoehner, O.; Jinek, M.; Doudna, J. A., Evolution of CRISPR RNA recognition and processing by Cas6 endonucleases. Nucleic Acids Res. 2014, 42(2), 1341-53
-
(2014)
Nucleic Acids Res.
, vol.42
, Issue.2
, pp. 1341-1353
-
-
Niewoehner, O.1
Jinek, M.2
Doudna, J.A.3
-
155
-
-
84964313405
-
Comparison of TALE designer transcription factors and the CRISPR/dCas9 in regulation of gene expression by targeting enhancers
-
Gao, X.; Tsang, J. C. H.; Gaba, F.; Wu, D.; Lu, L.; Liu, P. Comparison of TALE designer transcription factors and the CRISPR/dCas9 in regulation of gene expression by targeting enhancers. Nucleic Acids Res. 2014, 42(20), e155.
-
(2014)
Nucleic Acids Res.
, vol.42
, Issue.20
, pp. e155
-
-
Gao, X.1
Tsang, J.C.H.2
Gaba, F.3
Wu, D.4
Lu, L.5
Liu, P.6
-
156
-
-
34548124567
-
The ClosTron: a universal gene knock-out system for the genus Clostridium
-
Heap, J. T.; Pennington, O. J.; Cartman, S. T.; Carter, G. P.; Minton, N. P. The ClosTron: a universal gene knock-out system for the genus Clostridium. J. Microbiol. Methods 2007, 70(3), 452-64.
-
(2007)
J. Microbiol. Methods
, vol.70
, Issue.3
, pp. 452-464
-
-
Heap, J.T.1
Pennington, O.J.2
Cartman, S.T.3
Carter, G.P.4
Minton, N.P.5
-
157
-
-
84871519181
-
TALENs: a widely applicable technology for targeted genome editing
-
Joung, J. K.; Sander, J. D. TALENs: a widely applicable technology for targeted genome editing. Nat. Rev. Mol. Cell Biol. 2013, 14(1), 49-55.
-
(2013)
Nat. Rev. Mol. Cell Biol.
, vol.14
, Issue.1
, pp. 49-55
-
-
Joung, J.K.1
Sander, J.D.2
-
158
-
-
80051535219
-
Genome Engineering With Zinc-Finger Nucleases
-
Carroll, D. Genome Engineering With Zinc-Finger Nucleases. Genetics 2011, 188(4), 773-782
-
(2011)
Genetics
, vol.188
, Issue.4
, pp. 773-782
-
-
Carroll, D.1
-
159
-
-
77953702888
-
Directed evolution of an enhanced and highly efficient FokI cleavage domain for Zinc Finger Nucleases
-
Guo, J.; Gaj, T.; Barbas, C. F. Directed evolution of an enhanced and highly efficient FokI cleavage domain for Zinc Finger Nucleases. J. Mol. Biol. 2010, 400(1), 96-107
-
(2010)
J. Mol. Biol.
, vol.400
, Issue.1
, pp. 96-107
-
-
Guo, J.1
Gaj, T.2
Barbas, C.F.3
-
160
-
-
45749145124
-
Zinc-finger Nucleases: The Next Generation Emerges
-
Cathomen, T.; Keith Joung, J. Zinc-finger Nucleases: The Next Generation Emerges. Mol. Ther. 2008, 16(7), 1200-7.
-
(2008)
Mol. Ther.
, vol.16
, Issue.7
, pp. 1200-1207
-
-
Cathomen, T.1
Keith Joung, J.2
-
161
-
-
68949161807
-
Programming cells by multiplex genome engineering and accelerated evolution
-
Wang, H. H.; Isaacs, F. J.; Carr, P. A.; Sun, Z. Z.; Xu, G.; Forest, C. R.; Church, G. M. Programming cells by multiplex genome engineering and accelerated evolution. Nature 2009, 460(7257), 894-8.
-
(2009)
Nature
, vol.460
, Issue.7257
, pp. 894-898
-
-
Wang, H.H.1
Isaacs, F.J.2
Carr, P.A.3
Sun, Z.Z.4
Xu, G.5
Forest, C.R.6
Church, G.M.7
-
162
-
-
84880684174
-
-
accessed January 13, 2015
-
National Renewable Energy Laboratory. Biomass Research. http://www.nrel.gov/biomass/biorefinery.html (accessed January 13, 2015).
-
Biomass Research
-
-
-
163
-
-
79551662521
-
Quantitative prediction of cellular metabolism with constraint-based models: the COBRA Toolbox v2.0
-
Schellenberger, J.; Que, R.; Fleming, R. M. T.; Thiele, I.; Orth, J. D.; Feist, A. M.; Zielinski, D. C.; Bordbar, A.; Lewis, N. E.; Rahmanian, S.; Kang, J.; Hyduke, D. R.; Palsson, B. O. Quantitative prediction of cellular metabolism with constraint-based models: the COBRA Toolbox v2.0. Nat. Protoc. 2011, 6(9), 1290-307
-
(2011)
Nat. Protoc.
, vol.6
, Issue.9
, pp. 1290-1307
-
-
Schellenberger, J.1
Que, R.2
Fleming, R.M.T.3
Thiele, I.4
Orth, J.D.5
Feist, A.M.6
Zielinski, D.C.7
Bordbar, A.8
Lewis, N.E.9
Rahmanian, S.10
Kang, J.11
Hyduke, D.R.12
Palsson, B.O.13
-
164
-
-
84881152495
-
COBRApy: constraints-based reconstruction and analysis for python
-
Ebrahim, A.; Lerman, J. A.; Palsson, B. O.; Hyduke, D. R. COBRApy: constraints-based reconstruction and analysis for python. BMC Systems Biology 2013, 7(1), 74.
-
(2013)
BMC Systems Biology
, vol.7
, Issue.1
, pp. 74
-
-
Ebrahim, A.1
Lerman, J.A.2
Palsson, B.O.3
Hyduke, D.R.4
-
165
-
-
44949279376
-
What is protein engineering?
-
Galzie, Z. What is protein engineering? Biochem. Educ. 1991, 19(2), 74-75.
-
(1991)
Biochem. Educ.
, vol.19
, Issue.2
, pp. 74-75
-
-
Galzie, Z.1
|