Olefin cyclopropanation via carbene transfer catalyzed by engineered cytochrome P450 enzymes

Science

Volumn 339, Issue 6117, 2013, Pages 307-310

  Coelho, Pedro S ^a   Brustad, Eric M ^b   Kannan, Arvind ^a   Arnold, Frances H ^a  

^a California Institute of Technology   (United States)

^b University of North Carolina at Chapel Hill   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKENE; CARBENE; CYTOCHROME P450; CYTOCHROME P450 2A1; CYTOCHROME P450 BM3; REAGENT; STYRENE DERIVATIVE;

BIOENGINEERING; CATALYSIS; CHEMICAL BONDING; CYTOCHROME; ENZYME ACTIVITY; ORGANIC COMPOUND; OXYGENATION;

ANIMAL CELL; ARTICLE; BACILLUS MEGATERIUM; BIOENGINEERING; BIOTRANSFORMATION; CATALYSIS; CHEMICAL REACTION; CONTROLLED STUDY; CYCLOPROPANATION; DIASTEREOISOMER; ENANTIOSELECTIVITY; ENZYME SYNTHESIS; NONHUMAN; OXIDATION; OXYGENATION; PRIORITY JOURNAL; STEREOCHEMISTRY;

EID: 84872495336     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1231434     Document Type: Article

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