In vivo base editing of post-mitotic sensory cells

Nature Communications

Volumn 9, Issue 1, 2018, Pages

  Yeh, Wei Hsi ^a,b,c,d,e   Chiang, Hao ^d,e   Rees, Holly A ^a,b,c   Edge, Albert S B ^d,e,f   Liu, David R ^a,b,c  

^a HARVARD UNIVERSITY   (United States)

^b HARVARD UNIVERSITY   (United States)

^c BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^d MASSACHUSETTS EYE AND EAR INFIRMARY   (United States)

^e HARVARD MEDICAL SCHOOL   (United States)

^f HARVARD STEM CELL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; DNA BASE; LIPID; PROTEIN; RNA; WNT PROTEIN;

CELL; DNA; GENETIC ENGINEERING; GENOMICS; LIPID; MUTATION; RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EMBRYO; GENE EDITING; GENE MUTATION; HIGH THROUGHPUT SEQUENCING; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INDEL MUTATION; INNER EAR; MITOSIS; MOUSE; NONHUMAN; NUCLEAR REPROGRAMMING; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; SENSORY NERVE CELL; SUSTENTACULAR CELL; UPREGULATION; WNT SIGNALING; ANIMAL; DOUBLE STRANDED DNA BREAK; GENETICS; HEK293 CELL LINE; INNER HAIR CELL; KNOCKOUT MOUSE; METABOLISM; MUTATION; NIH 3T3 CELL LINE; RECOMBINATION REPAIR; TRANSGENIC MOUSE;

ANIMALS; BETA CATENIN; DNA BREAKS, DOUBLE-STRANDED; HAIR CELLS, AUDITORY, INNER; HEK293 CELLS; HUMANS; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; MITOSIS; MUTATION; NIH 3T3 CELLS; RECOMBINATIONAL DNA REPAIR; WNT SIGNALING PATHWAY;

EID: 85048091733     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/s41467-018-04580-3     Document Type: Article

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