메뉴 건너뛰기




Volumn 831, Issue , 2018, Pages 52-59

Pro- and anti-inflammatory effects of short chain fatty acids on immune and endothelial cells

Author keywords

HDACs; Inflammation, GPCRs; MAPK; NF B; SCFA

Indexed keywords

ACETIC ACID; BUTYRIC ACID; CXCL1 CHEMOKINE; CXCL2 CHEMOKINE; FREE FATTY ACID RECEPTOR 2; FREE FATTY ACID RECEPTOR 3; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR 109A; HISTONE DEACETYLASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 15; INTERLEUKIN 17; INTERLEUKIN 4; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 3; MITOGEN ACTIVATED PROTEIN KINASE; MONOCYTE CHEMOTACTIC PROTEIN 1; PROPIONIC ACID; SHORT CHAIN FATTY ACID; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1; ANTIINFLAMMATORY AGENT; AUTACOID; CELL SURFACE RECEPTOR; FFAR3 PROTEIN, HUMAN; G-PROTEIN COUPLED RECEPTOR 43, HUMAN; HCAR2 PROTEIN, HUMAN; HISTONE DEACETYLASE INHIBITOR; NICOTINIC RECEPTOR; VOLATILE FATTY ACID;

EID: 85047180733     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2018.05.003     Document Type: Article
Times cited : (382)

References (113)
  • 4
    • 84988923392 scopus 로고    scopus 로고
    • Human and mouse monocytes display distinct signalling and cytokine profiles upon stimulation with FFAR2/FFAR3 short-chain fatty acid receptor agonists
    • Ang, Z., Er, J.Z., Tan, N.S., Lu, J., Liou, Y.C., Grosse, J., Ding, J.L., Human and mouse monocytes display distinct signalling and cytokine profiles upon stimulation with FFAR2/FFAR3 short-chain fatty acid receptor agonists. Sci. Rep., 6, 2016, 34145.
    • (2016) Sci. Rep. , vol.6 , pp. 34145
    • Ang, Z.1    Er, J.Z.2    Tan, N.S.3    Lu, J.4    Liou, Y.C.5    Grosse, J.6    Ding, J.L.7
  • 5
    • 77952744684 scopus 로고    scopus 로고
    • Butyrate and propionate induced activated or non-activated neutrophil apoptosis via HDAC inhibitor activity but without activating GPR-41/GPR-43 pathways
    • Aoyama, M., Kotani, J., Usami, M., Butyrate and propionate induced activated or non-activated neutrophil apoptosis via HDAC inhibitor activity but without activating GPR-41/GPR-43 pathways. Nutrition 26 (2010), 653–661.
    • (2010) Nutrition , vol.26 , pp. 653-661
    • Aoyama, M.1    Kotani, J.2    Usami, M.3
  • 6
    • 0034802887 scopus 로고    scopus 로고
    • Thep65 (RelA) subunit of NF-kappaB interacts with the histone deacetylase (HDAC) corepressors HDAC1 and HDAC2 to negatively regulate gene expression
    • Ashburner, B.P., Westerheide, S.D., Baldwin, A.S. Jr., Thep65 (RelA) subunit of NF-kappaB interacts with the histone deacetylase (HDAC) corepressors HDAC1 and HDAC2 to negatively regulate gene expression. Mol. Cell. Biol. 21 (2001), 7065–7077.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 7065-7077
    • Ashburner, B.P.1    Westerheide, S.D.2    Baldwin, A.S.3
  • 7
    • 0030747128 scopus 로고    scopus 로고
    • NF-kappa B as a frequent target for immunosuppressive and anti-inflammatory molecules
    • Baeuerle, P.A., Baichwal, V.R., NF-kappa B as a frequent target for immunosuppressive and anti-inflammatory molecules. Adv. Immunol. 65 (1997), 111–137.
    • (1997) Adv. Immunol. , vol.65 , pp. 111-137
    • Baeuerle, P.A.1    Baichwal, V.R.2
  • 8
    • 0030882260 scopus 로고    scopus 로고
    • n-butyrate downregulates the stimulatory function of peripheral blood-derived antigen-presenting cells: a potential mechanism for modulating T-cell responses by short-chain fatty acids
    • Bohmig, G.A., Krieger, P.M., Saemann, M.D., Wenhardt, C., Pohanka, E., Zlabinger, G.J., n-butyrate downregulates the stimulatory function of peripheral blood-derived antigen-presenting cells: a potential mechanism for modulating T-cell responses by short-chain fatty acids. Immunology 92 (1997), 234–243.
    • (1997) Immunology , vol.92 , pp. 234-243
    • Bohmig, G.A.1    Krieger, P.M.2    Saemann, M.D.3    Wenhardt, C.4    Pohanka, E.5    Zlabinger, G.J.6
  • 9
    • 84961217329 scopus 로고    scopus 로고
    • The pharmacology and function of receptors for short-chain fatty acids
    • Bolognini, D., Tobin, A.B., Milligan, G., Moss, C.E., The pharmacology and function of receptors for short-chain fatty acids. Mol. Pharmacol. 89 (2016), 388–398.
    • (2016) Mol. Pharmacol. , vol.89 , pp. 388-398
    • Bolognini, D.1    Tobin, A.B.2    Milligan, G.3    Moss, C.E.4
  • 11
    • 0027731546 scopus 로고
    • Plasma cytokine and endotoxin levels correlate with survival in patients with the sepsis syndrome
    • Casey, L.C., Balk, R.A., Bone, R.C., Plasma cytokine and endotoxin levels correlate with survival in patients with the sepsis syndrome. Ann. Intern. Med. 119 (1993), 771–778.
    • (1993) Ann. Intern. Med. , vol.119 , pp. 771-778
    • Casey, L.C.1    Balk, R.A.2    Bone, R.C.3
  • 13
    • 84893859801 scopus 로고    scopus 로고
    • The microbial metabolite butyrate regulates intestinal macrophage function via histone deacetylase inhibition
    • Chang, P.V., Hao, L., Offermanns, S., Medzhitov, R., The microbial metabolite butyrate regulates intestinal macrophage function via histone deacetylase inhibition. Proc. Natl. Acad. Sci. USA 111 (2014), 2247–2252.
    • (2014) Proc. Natl. Acad. Sci. USA , vol.111 , pp. 2247-2252
    • Chang, P.V.1    Hao, L.2    Offermanns, S.3    Medzhitov, R.4
  • 14
    • 0035979737 scopus 로고    scopus 로고
    • Duration of nuclear NF-kappaB action regulated by reversible acetylation
    • Chen, L., Fischle, W., Verdin, E., Greene, W.C., Duration of nuclear NF-kappaB action regulated by reversible acetylation. Science 293 (2001), 1653–1657.
    • (2001) Science , vol.293 , pp. 1653-1657
    • Chen, L.1    Fischle, W.2    Verdin, E.3    Greene, W.C.4
  • 18
    • 84879101770 scopus 로고    scopus 로고
    • Epigenetics in sepsis: targeting histone deacetylases
    • Ciarlo, E., Savva, A., Roger, T., Epigenetics in sepsis: targeting histone deacetylases. Int. J. Antimicrob. Agents 42 (2013), Suppl, S8–12.
    • (2013) Int. J. Antimicrob. Agents , vol.42 , pp. Suppl S8-12
    • Ciarlo, E.1    Savva, A.2    Roger, T.3
  • 20
    • 32844469977 scopus 로고    scopus 로고
    • Lipopolysaccharide signaling in endothelial cells
    • Dauphinee, S.M., Karsan, A., Lipopolysaccharide signaling in endothelial cells. Lab. Investig. 86 (2006), 9–22.
    • (2006) Lab. Investig. , vol.86 , pp. 9-22
    • Dauphinee, S.M.1    Karsan, A.2
  • 21
    • 0038676409 scopus 로고    scopus 로고
    • Inhibition of histone deacetylase activity by butyrate
    • Davie, J.R., Inhibition of histone deacetylase activity by butyrate. J. Nutr. 133 (2003), 2485s–2493s.
    • (2003) J. Nutr. , vol.133 , pp. 2485s-2493s
    • Davie, J.R.1
  • 22
    • 84929878466 scopus 로고    scopus 로고
    • The promise and perils of HDAC inhibitors in neurodegeneration
    • Didonna, A., Opal, P., The promise and perils of HDAC inhibitors in neurodegeneration. Ann. Clin. Transl. Neurol. 2 (2015), 79–101.
    • (2015) Ann. Clin. Transl. Neurol. , vol.2 , pp. 79-101
    • Didonna, A.1    Opal, P.2
  • 24
    • 28944449684 scopus 로고    scopus 로고
    • Diet and inflammation: a link to metabolic and cardiovascular diseases
    • Esposito, K., Giugliano, D., Diet and inflammation: a link to metabolic and cardiovascular diseases. Eur. Heart J. 27 (2006), 15–20.
    • (2006) Eur. Heart J. , vol.27 , pp. 15-20
    • Esposito, K.1    Giugliano, D.2
  • 26
    • 2342510314 scopus 로고    scopus 로고
    • Identification of beta-arrestin2 as a G protein-coupled receptor-stimulated regulator of NF-kappaB pathways
    • Gao, H., Sun, Y., Wu, Y., Luan, B., Wang, Y., Qu, B., Pei, G., Identification of beta-arrestin2 as a G protein-coupled receptor-stimulated regulator of NF-kappaB pathways. Mol. Cell 14 (2004), 303–317.
    • (2004) Mol. Cell , vol.14 , pp. 303-317
    • Gao, H.1    Sun, Y.2    Wu, Y.3    Luan, B.4    Wang, Y.5    Qu, B.6    Pei, G.7
  • 27
    • 0029846775 scopus 로고    scopus 로고
    • The inflammatory cytokines. New developments in the pathophysiology and treatment of septic shock
    • Glauser, M.P., The inflammatory cytokines. New developments in the pathophysiology and treatment of septic shock. Drugs 52:Suppl. 2 (1996), S9–S17.
    • (1996) Drugs , vol.52 , pp. S9-S17
    • Glauser, M.P.1
  • 28
    • 0035862199 scopus 로고    scopus 로고
    • The human histone deacetylase family
    • Gray, S.G., Ekstrom, T.J., The human histone deacetylase family. Exp. Cell Res. 262 (2001), 75–83.
    • (2001) Exp. Cell Res. , vol.262 , pp. 75-83
    • Gray, S.G.1    Ekstrom, T.J.2
  • 29
    • 33947497538 scopus 로고    scopus 로고
    • Endothelial dysfunction: cardiovascular risk factors, therapy, and outcome
    • Hadi, H.A., Carr, C.S., Al Suwaidi, J., Endothelial dysfunction: cardiovascular risk factors, therapy, and outcome. Vasc. Health Risk Manag. 1 (2005), 183–198.
    • (2005) Vasc. Health Risk Manag. , vol.1 , pp. 183-198
    • Hadi, H.A.1    Carr, C.S.2    Al Suwaidi, J.3
  • 31
    • 85010424350 scopus 로고    scopus 로고
    • Soluble fibre meal challenge reduces airway inflammation and expression of GPR43 and GPR41 in asthma
    • Halnes, I., Baines, K.J., Berthon, B.S., MacDonald-Wicks, L.K., Gibson, P.G., Wood, L.G., Soluble fibre meal challenge reduces airway inflammation and expression of GPR43 and GPR41 in asthma. Nutrients, 9, 2017, 57.
    • (2017) Nutrients , vol.9 , pp. 57
    • Halnes, I.1    Baines, K.J.2    Berthon, B.S.3    MacDonald-Wicks, L.K.4    Gibson, P.G.5    Wood, L.G.6
  • 33
    • 0032567902 scopus 로고    scopus 로고
    • Pharmacological modulation of cell adhesion molecules
    • Henricks, P.A.J., Nijkamp, F.P., Pharmacological modulation of cell adhesion molecules. Eur. J. Pharmacol. 344 (1998), 1–13.
    • (1998) Eur. J. Pharmacol. , vol.344 , pp. 1-13
    • Henricks, P.A.J.1    Nijkamp, F.P.2
  • 34
    • 85047207363 scopus 로고    scopus 로고
    • Butyrate modulates Cav-1 and its binding partner AhR, leading to differential Cyp1a1 and Cyp1b1 gene expression in vascular endothelial cells
    • Hoffman, J.B., Petriello, M.C., Hennig, B., Butyrate modulates Cav-1 and its binding partner AhR, leading to differential Cyp1a1 and Cyp1b1 gene expression in vascular endothelial cells. FASEB J., 30, 2016, 1175.
    • (2016) FASEB J. , vol.30 , pp. 1175
    • Hoffman, J.B.1    Petriello, M.C.2    Hennig, B.3
  • 35
    • 85002157866 scopus 로고    scopus 로고
    • The role of short-chain fatty acids in kidney injury induced by gut-derived inflammatory response
    • Huang, W., Zhou, L., Guo, H., Xu, Y., Xu, Y., The role of short-chain fatty acids in kidney injury induced by gut-derived inflammatory response. Metabolism 68 (2017), 20–30.
    • (2017) Metabolism , vol.68 , pp. 20-30
    • Huang, W.1    Zhou, L.2    Guo, H.3    Xu, Y.4    Xu, Y.5
  • 39
    • 84899856633 scopus 로고    scopus 로고
    • Histone deacetylase isoforms regulate innate immune responses by deacetylating mitogen-activated protein kinase phosphatase-1
    • Jeong, Y., Du, R., Zhu, X., Yin, S., Wang, J., Cui, H., Cao, W., Lowenstein, C.J., Histone deacetylase isoforms regulate innate immune responses by deacetylating mitogen-activated protein kinase phosphatase-1. J. Leukoc. Biol. 95 (2014), 651–659.
    • (2014) J. Leukoc. Biol. , vol.95 , pp. 651-659
    • Jeong, Y.1    Du, R.2    Zhu, X.3    Yin, S.4    Wang, J.5    Cui, H.6    Cao, W.7    Lowenstein, C.J.8
  • 40
    • 84927934357 scopus 로고    scopus 로고
    • Dietary gut microbial metabolites, short-chain fatty acids, and host metabolic regulation
    • Kasubuchi, M., Hasegawa, S., Hiramatsu, T., Ichimura, A., Kimura, I., Dietary gut microbial metabolites, short-chain fatty acids, and host metabolic regulation. Nutrients 7 (2015), 2839–2849.
    • (2015) Nutrients , vol.7 , pp. 2839-2849
    • Kasubuchi, M.1    Hasegawa, S.2    Hiramatsu, T.3    Ichimura, A.4    Kimura, I.5
  • 41
    • 0023065124 scopus 로고
    • Effects of intravenous injection of butyrate on the exocrine pancreatic secretion in guinea pigs
    • Katoh, K., Tsuda, T., Effects of intravenous injection of butyrate on the exocrine pancreatic secretion in guinea pigs. Comp. Biochem. Physiol. A Comp. Physiol. 87 (1987), 569–572.
    • (1987) Comp. Biochem. Physiol. A Comp. Physiol. , vol.87 , pp. 569-572
    • Katoh, K.1    Tsuda, T.2
  • 42
    • 77952695807 scopus 로고    scopus 로고
    • Acetate, the key modulator of inflammatory responses in acute alcoholic hepatitis
    • Kendrick, S.F., O'Boyle, G., Mann, J., Zeybel, M., Palmer, J., Jones, D.E., Day, C.P., Acetate, the key modulator of inflammatory responses in acute alcoholic hepatitis. Hepatology 51 (2010), 1988–1997.
    • (2010) Hepatology , vol.51 , pp. 1988-1997
    • Kendrick, S.F.1    O'Boyle, G.2    Mann, J.3    Zeybel, M.4    Palmer, J.5    Jones, D.E.6    Day, C.P.7
  • 43
    • 79952932076 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors: molecular mechanisms of action and clinical trials as anti-cancer drugs
    • Kim, H.J., Bae, S.C., Histone deacetylase inhibitors: molecular mechanisms of action and clinical trials as anti-cancer drugs. Am. J. Transl. Res. 3 (2011), 166–179.
    • (2011) Am. J. Transl. Res. , vol.3 , pp. 166-179
    • Kim, H.J.1    Bae, S.C.2
  • 44
    • 84880620577 scopus 로고    scopus 로고
    • Short-chain fatty acids activate GPR41 and GPR43 on intestinal epithelial cells to promote inflammatory responses in mice
    • Kim, M.H., Kang, S.G., Park, J.H., Yanagisawa, M., Kim, C.H., Short-chain fatty acids activate GPR41 and GPR43 on intestinal epithelial cells to promote inflammatory responses in mice. Gastroenterology 145 (2013), 396–406.
    • (2013) Gastroenterology , vol.145 , pp. 396-406
    • Kim, M.H.1    Kang, S.G.2    Park, J.H.3    Yanagisawa, M.4    Kim, C.H.5
  • 45
    • 84896944617 scopus 로고    scopus 로고
    • Perspectives on the therapeutic potential of short-chain fatty acid receptors
    • Kim, S., Kim, J.H., Park, B.O., Kwak, Y.S., Perspectives on the therapeutic potential of short-chain fatty acid receptors. BMB Rep. 47 (2014), 173–178.
    • (2014) BMB Rep. , vol.47 , pp. 173-178
    • Kim, S.1    Kim, J.H.2    Park, B.O.3    Kwak, Y.S.4
  • 46
    • 21744447354 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha-mediated reduction of KLF2 is due to inhibition of MEF2 by NF-kappaB and histone deacetylases
    • Kumar, A., Lin, Z., SenBanerjee, S., Jain, M.K., Tumor necrosis factor alpha-mediated reduction of KLF2 is due to inhibition of MEF2 by NF-kappaB and histone deacetylases. Mol. Cell. Biol. 25 (2005), 5893–5903.
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 5893-5903
    • Kumar, A.1    Lin, Z.2    SenBanerjee, S.3    Jain, M.K.4
  • 48
    • 84863135417 scopus 로고    scopus 로고
    • Role of histone deacetylases in transcription factor regulation and cell cycle modulation in endothelial cells in response to disturbed flow
    • Lee, D.Y., Lee, C.I., Lin, T.E., Lim, S.H., Zhou, J., Tseng, Y.C., Chien, S., Chiu, J.J., Role of histone deacetylases in transcription factor regulation and cell cycle modulation in endothelial cells in response to disturbed flow. Proc. Natl. Acad. Sci. USA 109 (2012), 1967–1972.
    • (2012) Proc. Natl. Acad. Sci. USA , vol.109 , pp. 1967-1972
    • Lee, D.Y.1    Lee, C.I.2    Lin, T.E.3    Lim, S.H.4    Zhou, J.5    Tseng, Y.C.6    Chien, S.7    Chiu, J.J.8
  • 50
    • 85044166616 scopus 로고    scopus 로고
    • Time and concentration dependent effects of short chain fatty acids on lipopolysaccharide-or tumor necrosis factor α-induced endothelial activation
    • Li, M., Van Esch, B.E.C., Henricks, P.A.J., Garssen, J., Folkerts, G., Time and concentration dependent effects of short chain fatty acids on lipopolysaccharide-or tumor necrosis factor α-induced endothelial activation. Front. Pharmacol., 9, 2018, 233.
    • (2018) Front. Pharmacol. , vol.9 , pp. 233
    • Li, M.1    Van Esch, B.E.C.2    Henricks, P.A.J.3    Garssen, J.4    Folkerts, G.5
  • 51
    • 84863526492 scopus 로고    scopus 로고
    • Nitric oxide modifies chromatin to suppress ICAM-1 expression during colonic inflammation
    • Li, Q., Sarna, S.K., Nitric oxide modifies chromatin to suppress ICAM-1 expression during colonic inflammation. Am. J. Physiol. Gastrointest. Liver Physiol. 303 (2012), G103–G110.
    • (2012) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.303 , pp. G103-G110
    • Li, Q.1    Sarna, S.K.2
  • 52
    • 84899632877 scopus 로고    scopus 로고
    • Dietary fiber intake and mortality among survivors of myocardial infarction: prospective cohort study
    • Li, S., Flint, A., Pai, J.K., Forman, J.P., Hu, F.B., Willett, W.C., Rexrode, K.M., Mukamal, K.J., Rimm, E.B., Dietary fiber intake and mortality among survivors of myocardial infarction: prospective cohort study. BMJ, 348, 2014, g2659.
    • (2014) BMJ , vol.348 , pp. g2659
    • Li, S.1    Flint, A.2    Pai, J.K.3    Forman, J.P.4    Hu, F.B.5    Willett, W.C.6    Rexrode, K.M.7    Mukamal, K.J.8    Rimm, E.B.9
  • 53
    • 84910039691 scopus 로고    scopus 로고
    • Histone deacetylase inhibition and dietary short-chain fatty acids
    • Licciardi, P.V., Ververis, K., Karagiannis, T.C., Histone deacetylase inhibition and dietary short-chain fatty acids. ISRN Allergy, 2011, 2011, 869647.
    • (2011) ISRN Allergy , vol.2011 , pp. 869647
    • Licciardi, P.V.1    Ververis, K.2    Karagiannis, T.C.3
  • 54
    • 33645116785 scopus 로고    scopus 로고
    • NF-kappa B activation as a pathological mechanism of septic shock and inflammation
    • Liu, S.F., Malik, A.B., NF-kappa B activation as a pathological mechanism of septic shock and inflammation. Am. J. Physiol. Lung Cell Mol. Physiol. 290 (2006), L622–L645.
    • (2006) Am. J. Physiol. Lung Cell Mol. Physiol. , vol.290 , pp. L622-L645
    • Liu, S.F.1    Malik, A.B.2
  • 55
    • 84883473232 scopus 로고    scopus 로고
    • Synbiotic consumption changes the metabolism and composition of the gut microbiota in older people and modifies inflammatory processes: a randomised, double-blind, placebo-controlled crossover study
    • Macfarlane, S., Cleary, S., Bahrami, B., Reynolds, N., Macfarlane, G.T., Synbiotic consumption changes the metabolism and composition of the gut microbiota in older people and modifies inflammatory processes: a randomised, double-blind, placebo-controlled crossover study. Aliment. Pharmacol. Ther. 38 (2013), 804–816.
    • (2013) Aliment. Pharmacol. Ther. , vol.38 , pp. 804-816
    • Macfarlane, S.1    Cleary, S.2    Bahrami, B.3    Reynolds, N.4    Macfarlane, G.T.5
  • 56
    • 0034964508 scopus 로고    scopus 로고
    • TNF signaling in vascular endothelial cells
    • Madge, L.A., Pober, J.S., TNF signaling in vascular endothelial cells. Exp. Mol. Pathol. 70 (2001), 317–325.
    • (2001) Exp. Mol. Pathol. , vol.70 , pp. 317-325
    • Madge, L.A.1    Pober, J.S.2
  • 57
    • 61849183060 scopus 로고    scopus 로고
    • Expression and localization of GPR109A (PUMA-G/HM74A) mRNA and protein in mammalian retinal pigment epithelium
    • Martin, P.M., Ananth, S., Cresci, G., Roon, P., Smith, S., Ganapathy, V., Expression and localization of GPR109A (PUMA-G/HM74A) mRNA and protein in mammalian retinal pigment epithelium. Mol. Vis. 15 (2009), 362–372.
    • (2009) Mol. Vis. , vol.15 , pp. 362-372
    • Martin, P.M.1    Ananth, S.2    Cresci, G.3    Roon, P.4    Smith, S.5    Ganapathy, V.6
  • 60
    • 58649100256 scopus 로고    scopus 로고
    • Monocyte-endothelial cell interactions in the development of atherosclerosis
    • Mestas, J., Ley, K., Monocyte-endothelial cell interactions in the development of atherosclerosis. Trends Cardiovasc. Med. 18 (2008), 228–232.
    • (2008) Trends Cardiovasc. Med. , vol.18 , pp. 228-232
    • Mestas, J.1    Ley, K.2
  • 61
    • 19544364896 scopus 로고    scopus 로고
    • Short-chain fatty acids modulate gene expression for vascular endothelial cell adhesion molecules
    • Miller, S.J., Zaloga, G.P., Hoggatt, A.M., Labarrere, C., Faulk, W.P., Short-chain fatty acids modulate gene expression for vascular endothelial cell adhesion molecules. Nutrition 21 (2005), 740–748.
    • (2005) Nutrition , vol.21 , pp. 740-748
    • Miller, S.J.1    Zaloga, G.P.2    Hoggatt, A.M.3    Labarrere, C.4    Faulk, W.P.5
  • 62
    • 79953036634 scopus 로고    scopus 로고
    • Oral administration of tributyrin increases concentration of butyrate in the portal vein and prevents lipopolysaccharide-induced liver injury in rats
    • Miyoshi, M., Sakaki, H., Usami, M., Iizuka, N., Shuno, K., Aoyama, M., Usami, Y., Oral administration of tributyrin increases concentration of butyrate in the portal vein and prevents lipopolysaccharide-induced liver injury in rats. Clin. Nutr. 30 (2011), 252–258.
    • (2011) Clin. Nutr. , vol.30 , pp. 252-258
    • Miyoshi, M.1    Sakaki, H.2    Usami, M.3    Iizuka, N.4    Shuno, K.5    Aoyama, M.6    Usami, Y.7
  • 63
    • 53449083935 scopus 로고    scopus 로고
    • Short-chain fatty acids and trichostatin A alter tight junction permeability in human umbilical vein endothelial cells
    • Miyoshi, M., Usami, M., Ohata, A., Short-chain fatty acids and trichostatin A alter tight junction permeability in human umbilical vein endothelial cells. Nutrition 24 (2008), 1189–1198.
    • (2008) Nutrition , vol.24 , pp. 1189-1198
    • Miyoshi, M.1    Usami, M.2    Ohata, A.3
  • 64
    • 84961200851 scopus 로고    scopus 로고
    • Formation of short chain fatty acids by the gut microbiota and their impact on human metabolism
    • Morrison, D.J., Preston, T., Formation of short chain fatty acids by the gut microbiota and their impact on human metabolism. Gut Microbes 7 (2016), 189–200.
    • (2016) Gut Microbes , vol.7 , pp. 189-200
    • Morrison, D.J.1    Preston, T.2
  • 65
    • 77952482463 scopus 로고    scopus 로고
    • Histone deacetylase inhibitor, butyrate, attenuates lipopolysaccharide-induced acute lung injury in mice
    • Ni, Y.-F., Wang, J., Yan, X.-L., Tian, F., Zhao, J.-B., Wang, Y.-J., Jiang, T., Histone deacetylase inhibitor, butyrate, attenuates lipopolysaccharide-induced acute lung injury in mice. Respir. Res., 11, 2010, 33.
    • (2010) Respir. Res. , vol.11 , pp. 33
    • Ni, Y.-F.1    Wang, J.2    Yan, X.-L.3    Tian, F.4    Zhao, J.-B.5    Wang, Y.-J.6    Jiang, T.7
  • 68
    • 77956058729 scopus 로고    scopus 로고
    • Epigenetics and cardiovascular disease
    • Ordovas, J.M., Smith, C.E., Epigenetics and cardiovascular disease. Nat. Rev. Cardiol. 7 (2010), 510–519.
    • (2010) Nat. Rev. Cardiol. , vol.7 , pp. 510-519
    • Ordovas, J.M.1    Smith, C.E.2
  • 69
    • 0033596121 scopus 로고    scopus 로고
    • Activators and target genes of Rel/NF-kappaB transcription factors
    • Pahl, H.L., Activators and target genes of Rel/NF-kappaB transcription factors. Oncogene 18 (1999), 6853–6866.
    • (1999) Oncogene , vol.18 , pp. 6853-6866
    • Pahl, H.L.1
  • 71
    • 79959854675 scopus 로고    scopus 로고
    • Biomarkers of endothelial dysfunction: can they help us deciphering systemic inflammation and sepsis?
    • Paulus, P., Jennewein, C., Zacharowski, K., Biomarkers of endothelial dysfunction: can they help us deciphering systemic inflammation and sepsis?. Biomarkers 16:Suppl. 1 (2011), S11–S21.
    • (2011) Biomarkers , vol.16 , pp. S11-S21
    • Paulus, P.1    Jennewein, C.2    Zacharowski, K.3
  • 72
    • 79954578046 scopus 로고    scopus 로고
    • C/ebpalpha and C/ebpalpha oncoproteins regulate nfkb1 and displace histone deacetylases from NF-kappaB p50 homodimers to induce NF-kappaB target genes
    • Paz-Priel, I., Houng, S., Dooher, J., Friedman, A.D., C/ebpalpha and C/ebpalpha oncoproteins regulate nfkb1 and displace histone deacetylases from NF-kappaB p50 homodimers to induce NF-kappaB target genes. Blood 117 (2011), 4085–4094.
    • (2011) Blood , vol.117 , pp. 4085-4094
    • Paz-Priel, I.1    Houng, S.2    Dooher, J.3    Friedman, A.D.4
  • 73
    • 84899435428 scopus 로고    scopus 로고
    • A novel SCFA receptor, the microbiota, and blood pressure regulation
    • Pluznick, J., A novel SCFA receptor, the microbiota, and blood pressure regulation. Gut Microbes 5 (2014), 202–207.
    • (2014) Gut Microbes , vol.5 , pp. 202-207
    • Pluznick, J.1
  • 76
    • 67849090570 scopus 로고    scopus 로고
    • The fate of monocytes in atherosclerosis
    • Randolph, G.J., The fate of monocytes in atherosclerosis. J. Thromb. Haemost. 7 (2009), 28–30.
    • (2009) J. Thromb. Haemost. , vol.7 , pp. 28-30
    • Randolph, G.J.1
  • 77
    • 84862875593 scopus 로고    scopus 로고
    • Multiple roles of class I HDACs in proliferation, differentiation, and development
    • Reichert, N., Choukrallah, M.A., Matthias, P., Multiple roles of class I HDACs in proliferation, differentiation, and development. Cell. Mol. Life Sci. 69 (2012), 2173–2187.
    • (2012) Cell. Mol. Life Sci. , vol.69 , pp. 2173-2187
    • Reichert, N.1    Choukrallah, M.A.2    Matthias, P.3
  • 79
    • 34248631385 scopus 로고    scopus 로고
    • The role of histone deacetylases (HDACs) in human cancer
    • Ropero, S., Esteller, M., The role of histone deacetylases (HDACs) in human cancer. Mol. Oncol. 1 (2007), 19–25.
    • (2007) Mol. Oncol. , vol.1 , pp. 19-25
    • Ropero, S.1    Esteller, M.2
  • 80
    • 0033552883 scopus 로고    scopus 로고
    • Atherosclerosis–an inflammatory disease
    • Ross, R., Atherosclerosis–an inflammatory disease. N. Engl. J. Med. 340 (1999), 115–126.
    • (1999) N. Engl. J. Med. , vol.340 , pp. 115-126
    • Ross, R.1
  • 81
    • 0027445164 scopus 로고
    • The role of endothelium in cardiovascular homeostasis and diseases
    • Rubanyi, G.M., The role of endothelium in cardiovascular homeostasis and diseases. J. Cardiovasc. Pharmacol. 22:Suppl. 4 (1993), S1–S14.
    • (1993) J. Cardiovasc. Pharmacol. , vol.22 , pp. S1-S14
    • Rubanyi, G.M.1
  • 83
    • 0035666867 scopus 로고    scopus 로고
    • PUMA-G, an IFN-gamma-inducible gene in macrophages is a novel member of the seven transmembrane spanning receptor superfamily
    • Schaub, A., Futterer, A., Pfeffer, K., PUMA-G, an IFN-gamma-inducible gene in macrophages is a novel member of the seven transmembrane spanning receptor superfamily. Eur. J. Immunol. 31 (2001), 3714–3725.
    • (2001) Eur. J. Immunol. , vol.31 , pp. 3714-3725
    • Schaub, A.1    Futterer, A.2    Pfeffer, K.3
  • 84
    • 84883717655 scopus 로고    scopus 로고
    • Dietary inhibitors of histone deacetylases in intestinal immunity and homeostasis
    • Schilderink, R., Verseijden, C., de Jonge, W.J., Dietary inhibitors of histone deacetylases in intestinal immunity and homeostasis. Front. Immunol., 4, 2013, 226.
    • (2013) Front. Immunol. , vol.4 , pp. 226
    • Schilderink, R.1    Verseijden, C.2    de Jonge, W.J.3
  • 85
    • 84864053102 scopus 로고    scopus 로고
    • Receptor-specific regulation of ERK1/2 activation by members of the “free fatty acid receptor” family
    • Seljeset, S., Siehler, S., Receptor-specific regulation of ERK1/2 activation by members of the “free fatty acid receptor” family. J. Recept. Signal Transduct. Res. 32 (2012), 196–201.
    • (2012) J. Recept. Signal Transduct. Res. , vol.32 , pp. 196-201
    • Seljeset, S.1    Siehler, S.2
  • 89
    • 85014080866 scopus 로고    scopus 로고
    • Key questions for translation of FFA receptors: from pharmacology to medicines
    • Suckow, A.T., Briscoe, C.P., Key questions for translation of FFA receptors: from pharmacology to medicines. Handb. Exp. Pharmacol. 236 (2017), 101–131.
    • (2017) Handb. Exp. Pharmacol. , vol.236 , pp. 101-131
    • Suckow, A.T.1    Briscoe, C.P.2
  • 90
    • 84979220456 scopus 로고    scopus 로고
    • Microbiota metabolite short chain fatty acids, GPCR, and inflammatory bowel diseases
    • Sun, M., Wu, W., Liu, Z., Cong, Y., Microbiota metabolite short chain fatty acids, GPCR, and inflammatory bowel diseases. J. Gastroenterol. 52 (2017), 1–8.
    • (2017) J. Gastroenterol. , vol.52 , pp. 1-8
    • Sun, M.1    Wu, W.2    Liu, Z.3    Cong, Y.4
  • 91
    • 84872166189 scopus 로고    scopus 로고
    • Leukocyte behavior in atherosclerosis, myocardial infarction, and heart failure
    • Swirski, F.K., Nahrendorf, M., Leukocyte behavior in atherosclerosis, myocardial infarction, and heart failure. Science 339 (2013), 161–166.
    • (2013) Science , vol.339 , pp. 161-166
    • Swirski, F.K.1    Nahrendorf, M.2
  • 93
    • 51449119654 scopus 로고    scopus 로고
    • Roles of short-chain fatty acids receptors, GPR41 and GPR43 on colonic functions
    • Tazoe, H., Otomo, Y., Kaji, I., Tanaka, R., Karaki, S.I., Kuwahara, A., Roles of short-chain fatty acids receptors, GPR41 and GPR43 on colonic functions. J. Physiol. Pharmacol. 59:Suppl. 2 (2008), S251–S262.
    • (2008) J. Physiol. Pharmacol. , vol.59 , pp. S251-S262
    • Tazoe, H.1    Otomo, Y.2    Kaji, I.3    Tanaka, R.4    Karaki, S.I.5    Kuwahara, A.6
  • 94
    • 34347223232 scopus 로고    scopus 로고
    • Anti-inflammatory properties of the short-chain fatty acids acetate and propionate: a study with relevance to inflammatory bowel disease
    • Tedelind, S., Westberg, F., Kjerrulf, M., Vidal, A., Anti-inflammatory properties of the short-chain fatty acids acetate and propionate: a study with relevance to inflammatory bowel disease. World J. Gastroenterol. 13 (2007), 2826–2832.
    • (2007) World J. Gastroenterol. , vol.13 , pp. 2826-2832
    • Tedelind, S.1    Westberg, F.2    Kjerrulf, M.3    Vidal, A.4
  • 95
    • 84902657771 scopus 로고    scopus 로고
    • Diet, metabolites, and “western-lifestyle” inflammatory diseases
    • Thorburn, A.N., Macia, L., Mackay, C.R., Diet, metabolites, and “western-lifestyle” inflammatory diseases. Immunity 40 (2014), 833–842.
    • (2014) Immunity , vol.40 , pp. 833-842
    • Thorburn, A.N.1    Macia, L.2    Mackay, C.R.3
  • 97
    • 0034959553 scopus 로고    scopus 로고
    • Short-chain fatty acids and human colonic function: roles of resistant starch and nonstarch polysaccharides
    • Topping, D.L., Clifton, P.M., Short-chain fatty acids and human colonic function: roles of resistant starch and nonstarch polysaccharides. Physiol. Rev. 81 (2001), 1031–1064.
    • (2001) Physiol. Rev. , vol.81 , pp. 1031-1064
    • Topping, D.L.1    Clifton, P.M.2
  • 99
    • 84874395887 scopus 로고    scopus 로고
    • Short-chain free fatty acid receptors FFA2/GPR43 and FFA3/GPR41 as new potential therapeutic targets
    • Ulven, T., Short-chain free fatty acid receptors FFA2/GPR43 and FFA3/GPR41 as new potential therapeutic targets. Front. Endocrinol., 3, 2012, 111.
    • (2012) Front. Endocrinol. , vol.3 , pp. 111
    • Ulven, T.1
  • 100
    • 42949171444 scopus 로고    scopus 로고
    • Butyrate and trichostatin A attenuate nuclear factor kappaB activation and tumor necrosis factor alpha secretion and increase prostaglandin E2 secretion in human peripheral blood mononuclear cells
    • Usami, M., Kishimoto, K., Ohata, A., Miyoshi, M., Aoyama, M., Fueda, Y., Kotani, J., Butyrate and trichostatin A attenuate nuclear factor kappaB activation and tumor necrosis factor alpha secretion and increase prostaglandin E2 secretion in human peripheral blood mononuclear cells. Nutr. Res. 28 (2008), 321–328.
    • (2008) Nutr. Res. , vol.28 , pp. 321-328
    • Usami, M.1    Kishimoto, K.2    Ohata, A.3    Miyoshi, M.4    Aoyama, M.5    Fueda, Y.6    Kotani, J.7
  • 103
    • 70350141417 scopus 로고    scopus 로고
    • Short-chain fatty acids stimulate the migration of neutrophils to inflammatory sites
    • Vinolo, M.A., Rodrigues, H.G., Hatanaka, E., Hebeda, C.B., Farsky, S.H., Curi, R., Short-chain fatty acids stimulate the migration of neutrophils to inflammatory sites. Clin. Sci. 117 (2009), 331–338.
    • (2009) Clin. Sci. , vol.117 , pp. 331-338
    • Vinolo, M.A.1    Rodrigues, H.G.2    Hatanaka, E.3    Hebeda, C.B.4    Farsky, S.H.5    Curi, R.6
  • 104
    • 80051471073 scopus 로고    scopus 로고
    • Suppressive effect of short-chain fatty acids on production of proinflammatory mediators by neutrophils
    • Vinolo, M.A., Rodrigues, H.G., Hatanaka, E., Sato, F.T., Sampaio, S.C., Curi, R., Suppressive effect of short-chain fatty acids on production of proinflammatory mediators by neutrophils. J. Nutr. Biochem. 22 (2011), 849–855.
    • (2011) J. Nutr. Biochem. , vol.22 , pp. 849-855
    • Vinolo, M.A.1    Rodrigues, H.G.2    Hatanaka, E.3    Sato, F.T.4    Sampaio, S.C.5    Curi, R.6
  • 105
    • 80054980812 scopus 로고    scopus 로고
    • Regulation of inflammation by short chain fatty acids
    • Vinolo, M.A., Rodrigues, H.G., Nachbar, R.T., Curi, R., Regulation of inflammation by short chain fatty acids. Nutrients 3 (2011), 858–876.
    • (2011) Nutrients , vol.3 , pp. 858-876
    • Vinolo, M.A.1    Rodrigues, H.G.2    Nachbar, R.T.3    Curi, R.4
  • 107
    • 84865012300 scopus 로고    scopus 로고
    • Butyrate-induced GPR41 activation inhibits histone acetylation and cell growth
    • Wu, J., Zhou, Z., Hu, Y., Dong, S., Butyrate-induced GPR41 activation inhibits histone acetylation and cell growth. J. Genet. Genom. 39 (2012), 375–384.
    • (2012) J. Genet. Genom. , vol.39 , pp. 375-384
    • Wu, J.1    Zhou, Z.2    Hu, Y.3    Dong, S.4
  • 108
    • 84897402053 scopus 로고    scopus 로고
    • Epigenetics in vascular disease - therapeutic potential of new agents
    • Xu, S.S., Alam, S., Margariti, A., Epigenetics in vascular disease - therapeutic potential of new agents. Curr. Vasc. Pharmacol. 12 (2014), 77–86.
    • (2014) Curr. Vasc. Pharmacol. , vol.12 , pp. 77-86
    • Xu, S.S.1    Alam, S.2    Margariti, A.3
  • 109
    • 84896993870 scopus 로고    scopus 로고
    • Short-chain fatty acids from periodontal pathogens suppress histone deacetylases, EZH2, and SUV39H1 to promote Kaposi's sarcoma-associated herpesvirus replication
    • Yu, X., Shahir, A.M., Sha, J., Feng, Z., Eapen, B., Nithianantham, S., Das, B., Karn, J., Weinberg, A., Bissada, N.F., Ye, F., Short-chain fatty acids from periodontal pathogens suppress histone deacetylases, EZH2, and SUV39H1 to promote Kaposi's sarcoma-associated herpesvirus replication. J. Virol. 88 (2014), 4466–4479.
    • (2014) J. Virol. , vol.88 , pp. 4466-4479
    • Yu, X.1    Shahir, A.M.2    Sha, J.3    Feng, Z.4    Eapen, B.5    Nithianantham, S.6    Das, B.7    Karn, J.8    Weinberg, A.9    Bissada, N.F.10    Ye, F.11
  • 110
    • 68049092959 scopus 로고    scopus 로고
    • Propionate reduces the cytokine-induced VCAM-1 and ICAM-1 expression by inhibiting nuclear factor-kappa B (NF-kappaB) activation
    • Zapolska-Downar, D., Naruszewicz, M., Propionate reduces the cytokine-induced VCAM-1 and ICAM-1 expression by inhibiting nuclear factor-kappa B (NF-kappaB) activation. J. Physiol. Pharmacol. 60 (2009), 123–131.
    • (2009) J. Physiol. Pharmacol. , vol.60 , pp. 123-131
    • Zapolska-Downar, D.1    Naruszewicz, M.2
  • 111
    • 1842530955 scopus 로고    scopus 로고
    • Butyrate inhibits cytokine-induced VCAM-1 and ICAM-1 expression in cultured endothelial cells: the role of NF-kappaB and PPARalpha
    • Zapolska-Downar, D., Siennicka, A., Kaczmarczyk, M., Kolodziej, B., Naruszewicz, M., Butyrate inhibits cytokine-induced VCAM-1 and ICAM-1 expression in cultured endothelial cells: the role of NF-kappaB and PPARalpha. J. Nutr. Biochem. 15 (2004), 220–228.
    • (2004) J. Nutr. Biochem. , vol.15 , pp. 220-228
    • Zapolska-Downar, D.1    Siennicka, A.2    Kaczmarczyk, M.3    Kolodziej, B.4    Naruszewicz, M.5
  • 112
    • 0036203419 scopus 로고    scopus 로고
    • The phosphorylation status of nuclear NF-kappa B determines its association with CBP/p300 or HDAC-1
    • Zhong, H., May, M.J., Jimi, E., Ghosh, S., The phosphorylation status of nuclear NF-kappa B determines its association with CBP/p300 or HDAC-1. Mol. Cell 9 (2002), 625–636.
    • (2002) Mol. Cell , vol.9 , pp. 625-636
    • Zhong, H.1    May, M.J.2    Jimi, E.3    Ghosh, S.4
  • 113
    • 79957484652 scopus 로고    scopus 로고
    • Role of histone deacetylases in vascular cell homeostasis and arteriosclerosis
    • Zhou, B., Margariti, A., Zeng, L., Xu, Q., Role of histone deacetylases in vascular cell homeostasis and arteriosclerosis. Cardiovasc. Res. 90 (2011), 413–420.
    • (2011) Cardiovasc. Res. , vol.90 , pp. 413-420
    • Zhou, B.1    Margariti, A.2    Zeng, L.3    Xu, Q.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.