Short-chain fatty acids activate GPR41 and GPR43 on intestinal epithelial cells to promote inflammatory responses in mice

Gastroenterology

Volumn 145, Issue 2, 2013, Pages

  Kim, Myung H ^a   Kang, Seung G ^a   Park, Jeong H ^a   Yanagisawa, Masashi ^d   Kim, Chang H ^a,b,c  

^a PURDUE UNIVERSITY   (United States)

^b PURDUE UNIVERSITY   (United States)

^c Purdue University   (United States)

^d UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Mouse Model Colonic Inflammation Intestinal Barrier Leakage Pathogen

Indexed keywords

ALCOHOL; CXCL1 CHEMOKINE; CXCL2 CHEMOKINE; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR 41; G PROTEIN COUPLED RECEPTOR 43; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 12; INTERLEUKIN 17; INTERLEUKIN 6; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; MONOCYTE CHEMOTACTIC PROTEIN 1; SHORT CHAIN FATTY ACID; TRINITROBENZENESULFONIC ACID; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL CLEARANCE; BACTERIAL INFECTION; CELL ACTIVATION; CELLULAR IMMUNITY; CITROBACTER RODENTIUM; COLON; COLON MUCOSA; CONTROLLED STUDY; CYTOKINE PRODUCTION; EFFECTOR CELL; ENTERITIS; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; IMMUNOHISTOCHEMISTRY; IMMUNOREGULATION; INTESTINE EPITHELIUM CELL; INTESTINE MUCOSA PERMEABILITY; LAMINA PROPRIA; LEUKOCYTE; MOUSE; NEUTROPHIL CHEMOTAXIS; NEUTROPHIL COUNT; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; TH17 CELL;

EID: 84880620577     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2013.04.056     Document Type: Article

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