Short-chain fatty acids stimulate the migration of neutrophils to inflammatory sites

Clinical Science

Volumn 117, Issue 9, 2009, Pages 331-338

  Vinolo, Marco A R ^a   Rodrigues, Hosana G ^a   Hatanaka, Elaine ^a   Hebeda, Cristina B ^a   Farsky, Sandra H P ^a   Curi, Rui ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Anaerobic bacterium; Chemotaxis; Inflammation; Neutrophil; Short chain fatty acid

Indexed keywords

ACETIC ACID; BETA2 INTEGRIN; BUTYRIC ACID; CYTOKINE INDUCED NEUTROPHIL CHEMOATTRACTANT; CYTOKINE INDUCED NEUTROPHIL CHEMOATTRACTANT 2 ALPHA BETA; INTERLEUKIN 1BETA; L SELECTIN; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MESSENGER RNA; PROPIONIC ACID; SHORT CHAIN FATTY ACID; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL ADHESION; CELL MIGRATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; IN VITRO STUDY; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT;

ANIMALS; ANTIGENS, CD18; CELL ADHESION; CELLS, CULTURED; CHEMOTAXIS, LEUKOCYTE; CYTOKINES; FATTY ACIDS, VOLATILE; GENE EXPRESSION REGULATION; INFLAMMATION; L-SELECTIN; MALE; NEUTROPHIL INFILTRATION; NEUTROPHILS; RATS; RATS, WISTAR; RNA, MESSENGER;

EID: 70350141417     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/CS20080642     Document Type: Article

References (37)

1. McOrist, A. L., Abell, G. C., Cooke, C. and Nyland, K. (2008) Bacterial population dynamics and faecal short-chain fatty acid (SCFA) concentrations in healthy humans. Br. J. Nutr. 100, 138-146
2. Topping, D. L. and Clifton, P. M. (2001) Short-chain fatty acids and human colonic function: roles of resistant starch and nonstarch polysaccharides. Physiol. Rev. 81, 1031-1064
3. Niederman, R., Buyle-Bodin, Y., Lu, B. Y., Robinson, P. and Naleway, C. (1997) Short-chain carboxylic acid concentration in human gingival crevicular fluid. J. Dent. Res. 76, 575-579
4. Kurita-Ochiai, T., Fukushima, K. and Ochiai, K. (1995) Volatile fatty acids, metabolic by-products of periodontopathic bacteria, inhibit lymphocyte proliferation and cytokine production. J. Dent. Res. 74, 1367-1373
5. Ladas, S., Arapakis, G., Malamou-Ladas, H., Palikaris, G. and Arseni, A. (1979) Rapid diagnosis of anaerobic infections by gas-liquid chromatography. J. Clin. Pathol. 32, 1163-1167
6. Mills, S. W., Montgomery, S. H. and Morck, D. W. (2006) Evaluation of the effects of short-chain fatty acids and extracellular pH on bovine neutrophil function in vitro. Am. J. Vet. Res. 67, 1901-1907
7. Niederman, R., Zhang, J. and Kashket, S. (1997) Short-chain carboxylic-acid-stimulated, PMN-mediated gingival inflammation. Crit. Rev. Oral Biol. Med. 8, 269-290
8. Park, J. S., Lee, E. J., Lee, J. C., Kim, W. K. and Kim, H. S. (2007) Anti-inflammatory effects of short chain fatty acids in IFN-γ -stimulated RAW 264. 7 murine macrophage cells: involvement of NF-κB and ERK signaling pathways. Int. Immunopharmacol. 7, 70-77
9. Vinolo, M. A., Hatanaka, E., Lambertucci, R. H., Newsholme, P. and Curi, R. (2009) Effects of short chain fatty acids on effector mechanisms of neutrophils. Cell. Biochem. Funct. 27, 48-55
10. Mackay, C. R. (2008) Moving targets: cell migration inhibitors as new anti-inflammatory therapies. Nat. Immunol. 9, 988-998
11. Edwards, J. C., Sedgwick, A. D. and Willoughby, D. A. (1981) The formation of a structure with the features of synovial lining by subcutaneous injection of air: an in vivo tissue culture system. J. Pathol. 134, 147-156
12. Dahlen, S. E., Bjork, J., Hedqvist, P., Arfors, K. E., Hammarstrom, S., Lindgren, J. A. and Samuelsson, B. (1981) Leukotrienes promote plasma leakage and leukocyte adhesion in postcapillary venules: in vivo effects with relevance to the acute inflammatory response. Proc. Natl. Acad. Sci. U.S.A. 78, 3887-3891
13. Chomczynski, P. and Sacchi, N. (1987) Single-step method of RNA isolation by acid guanidinium thiocyanatephenol-chloroform extraction. Anal. Biochem. 162, 156-159
14. Higuchi, R., Dollinger, G., Walsh, P. S. and Griffith, R. (1992) Simultaneous amplification and detection of specific DNA sequences. Biotechnology 10, 413-417
15. Liu, W. and Saint, D. A. (2002) A new quantitative method of real time reverse transcription polymerase chain reaction assay based on simulation of polymerase chain reaction kinetics. Anal. Biochem. 302, 52-59
16. Selvatici, R., Falzarano, S., Mollica, A. and Spisani, S. (2006) Signal transduction pathways triggered by selective formylpeptide analogues in human neutrophils. Eur. J. Pharmacol. 534, 1-11
17. Le Poul, E., Loison, C., Struyf, S., Springael, J. Y., Lannoy, V., Decobecq, M. E., Brezillon, S., Dupriez, V., Vassart, G., Van Damme, J. et al. (2003) Functional characterization of human receptors for short chain fatty acids and their role in polymorphonuclear cell activation. J. Biol. Chem. 278, 25481-25489
18. Brunkhorst, B. A., Kraus, E., Coppi, M., Budnick, M. and Niederman, R. (1992) Propionate induces polymorphonuclear leukocyte activation and inhibits formylmethionyl-leucyl-phenylalanine-stimulated activation. Infect. Immun. 60, 2957-2968
19. 2+ in resting and stimulated human neutrophils by short-chain carboxylic acids at neutral pH. Infect. Immun. 60, 5307-5311
20. Brown, A. J., Goldsworthy, S. M., Barnes, A. A., Eilert, M. M., Tcheang, L., Daniels, D., Muir, A. I., Wigglesworth, M. J., Kinghorn, I., Fraser, N. J. et al. (2003) The orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids. J. Biol. Chem. 278, 11312-11319
21. Zapolska-Downar, D., Siennicka, A., Kaczmarczyk, M., Kolodziej, B. and Naruszewicz, M. (2004) Butyrate inhibits cytokine-induced VCAM-1 and ICAM-1 expression in cultured endothelial cells: the role of NF-κB and PPARα. J. Nutr. Biochem. 15, 220-228
22. Miller, S. J., Zaloga, G. P., Hoggatt, A. M., Labarrere, C. and Faulk, W. P. (2005) Short-chain fatty acids modulate gene expression for vascular endothelial cell adhesion molecules. Nutrition 21, 740-748
23. Ding, Z. M., Babensee, J. E., Simon, S. I., Lu, H., Perrard, J. L., Bullard, D. C., Dai, X. Y., Bromley, S. K., Dustin, M. L., Entman, M. L. et al. (1999) Relative contribution of LFA-1 and Mac-1 to neutrophil adhesion and migration. J. Immunol. 163, 5029-5038
24. Shibata, F., Konishi, K., Kato, H., Komorita, N., al-Mokdad, M., Fujioka, M. and Nakagawa, H. (1995) Recombinant production and biological properties of rat cytokine-induced neutrophil chemoattractants, GRO/CINC-2 α, CINC-2β and CINC-3. Eur. J. Biochem. 231, 306-311
25. Shibata, F., Konishi, K. and Nakagawa, H. (1998) Gene structure, cDNA cloning, and expression of the rat cytokine-induced neutrophil chemoattractant-2 (CINC-2) gene. Cytokine 10, 169-174
26. Ulich, T. R., Howard, S. C., Remick, D. G., Wittwer, A., Yi, E. S., Yin, S., Guo, K., Welply, J. K. and Williams, J. H. (1995) Intratracheal administration of endotoxin and cytokines. VI. Antiserum to CINC inhibits acute inflammation. Am. J. Physiol. 268, L245-L250
27. Shanley, T. P., Schmal, H., Warner, R. L., Schmid, E., Friedl, H. P. and Ward, P. A. (1997) Requirement for C-X-C chemokines (macrophage inflammatory protein-2 and cytokine-induced neutrophil chemoattractant) in IgG immune complex-induced lung injury. J. Immunol. 158, 3439-3448
28. Nakagawa, H., Shiota, S., Takano, K., Shibata, F. and Kato, H. (1996) Cytokine-induced neutrophil chemoattractant (CINC)-2 α, a novel member of rat GRO/CINCs, is a predominant chemokine produced by lipopolysaccharide-stimulated rat macrophages in culture. Biochem. Biophys. Res. Commun. 220, 945-948
29. Bocker, U., Nebe, T., Herweck, F., Holt, L., Panja, A., Jobin, C., Rossol, S., Sartor, R. B. and Singer, M. V. (2003) Butyrate modulates intestinal epithelial cell-mediated neutrophil migration. Clin. Exp. Immunol. 131, 53-60
30. Wilson, A. J., Byron, K. and Gibson, P. R. (1999) Interleukin-8 stimulates the migration of human colonic epithelial cells in vitro. Clin. Sci. 97, 385-390
31. Adam, E., Quivy, V., Bex, F., Chariot, A., Collette, Y., Vanhulle, C., Schoonbroodt, S., Goffin, V., Nguyen, T. L., Gloire, G. et al. (2003) Potentiation of tumor necrosis factor-induced NF-κB activation by deacetylase inhibitors is associated with a delayed cytoplasmic reappearance of IκBα. Mol. Cell. Biol. 23, 6200-6209
32. Huuskonen, J., Suuronen, T., Nuutinen, T., Kyrylenko, S. and Salminen, A. (2004) Regulation of microglial inflammatory response by sodium butyrate and short-chain fatty acids. Br. J. Pharmacol. 141, 874-880
33. Suuronen, T., Huuskonen, J., Nuutinen, T. and Salminen, A. (2006) Characterization of the pro-inflammatory signaling induced by protein acetylation in microglia. Neurochem. Int. 49, 610-618
34. Kida, Y., Shimizu, T. and Kuwano, K. (2006) Sodium butyrate up-regulates cathelicidin gene expression via activator protein-1 and histone acetylation at the promoter region in a human lung epithelial cell line, EBC-1. Mol. Immunol. 43, 1972-1981
35. Rotstein, O. D., Vittorini, T., Kao, J., McBurney, M. I., Nasmith, P. E. and Grinstein, S. (1989) A soluble Bacteroides by-product impairs phagocytic killing of Escherichia coli by neutrophils. Infect. Immun. 57, 745-753
36. Rotstein, O. D., Pruett, T. L. and Simmons, R. L. (1985) Lethal microbial synergism in intra-abdominal infections. Escherichia coli and Bacteroides fragilis. Arch. Surg. 120, 146-151
37. Stempelj, M., Kedinger, M., Augenlicht, L. and Klampfer, L. (2007) Essential role of the JAK/STAT1 signaling pathway in the expression of inducible nitric-oxide synthase in intestinal epithelial cells and its regulation by butyrate. J. Biol. Chem. 282, 9797-9804