메뉴 건너뛰기




Volumn 10, Issue 2, 2004, Pages 122-128

Butyrate inhibits leukocyte adhesion to endothelial cells via modulation of VCAM-1

Author keywords

Anti inflammatory effects; Butyrate; Human endothelial cells; Inflammatory bowel disease (IBD); Nuclear factor kappaB (NF B); Short chain fatty acids; Vascular cell adhesion molecule (VCAM)

Indexed keywords

BUTYRIC ACID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTEGRIN; INTERCELLULAR ADHESION MOLECULE 1; TUMOR NECROSIS FACTOR ALPHA; VASCULAR CELL ADHESION MOLECULE 1;

EID: 12144288656     PISSN: 10780998     EISSN: None     Source Type: Journal    
DOI: 10.1097/00054725-200403000-00010     Document Type: Article
Times cited : (74)

References (45)
  • 1
    • 0031470620 scopus 로고    scopus 로고
    • Cell adhesion and angiogenesis
    • Bischoff J. Cell adhesion and angiogenesis. J Clin Invest. 1997;100: S37-S39.
    • (1997) J. Clin. Invest. , vol.100
    • Bischoff, J.1
  • 3
    • 0033063325 scopus 로고    scopus 로고
    • VCAM-1 and ICAM-1 mediate leukocyte-endothelial cell adhesion in rat experimental colitis
    • Sans M, Panes J, Ardite E, et al. VCAM-1 and ICAM-1 mediate leukocyte-endothelial cell adhesion in rat experimental colitis. Gastroenterology. 1999;116:874-883.
    • (1999) Gastroenterology , vol.116 , pp. 874-883
    • Sans, M.1    Panes, J.2    Ardite, E.3
  • 4
    • 0035214691 scopus 로고    scopus 로고
    • Antibody blockade of ICAM-1 and VCAM-1 ameliorates inflammation in the SAMP-1/Yit adoptive transfer model of Crohn's disease in mice
    • Burns RC, Rivera-Nieves J, Moskaluk CA, et al. Antibody blockade of ICAM-1 and VCAM-1 ameliorates inflammation in the SAMP-1/Yit adoptive transfer model of Crohn's disease in mice. Gastroenterology. 2001;121:1428-1436.
    • (2001) Gastroenterology , vol.121 , pp. 1428-1436
    • Burns, R.C.1    Rivera-Nieves, J.2    Moskaluk, C.A.3
  • 5
    • 0037089033 scopus 로고    scopus 로고
    • Beta1 and beta2 integrins activate different signaling pathways in monocytes
    • Reyes-Reyes M, Mora N, Gonzalez G, et al. beta1 and beta2 integrins activate different signaling pathways in monocytes. Biochem J. 2002;363: 273-280.
    • (2002) Biochem. J. , vol.363 , pp. 273-280
    • Reyes-Reyes, M.1    Mora, N.2    Gonzalez, G.3
  • 6
    • 0035877113 scopus 로고    scopus 로고
    • Blockade of alpha 5 beta 1 integrins reverses the inhibitory effect of tenascin on chemotaxis of human monocytes and polymorphonuclear leukocytes through three-dimensional gels of extracellular matrix proteins
    • Loike JD, Cao L, Budhu S, et al. Blockade of alpha 5 beta 1 integrins reverses the inhibitory effect of tenascin on chemotaxis of human monocytes and polymorphonuclear leukocytes through three-dimensional gels of extracellular matrix proteins. J Immunol. 2001;166:7534-7542.
    • (2001) J. Immunol. , vol.166 , pp. 7534-7542
    • Loike, J.D.1    Cao, L.2    Budhu, S.3
  • 7
    • 0029836444 scopus 로고    scopus 로고
    • Local administration of antisense phosphorothioate oligonucleotides to the p65 subunit of NF-kappa B abrogates established experimental colitis in mice
    • Neurath MF, Pettersson S, Meyer zum Buschenfelde KH, et al. Local administration of antisense phosphorothioate oligonucleotides to the p65 subunit of NF-kappa B abrogates established experimental colitis in mice. Nat Med. 1996;2:998-1004.
    • (1996) Nat. Med. , vol.2 , pp. 998-1004
    • Neurath, M.F.1    Pettersson, S.2    Meyer zum Buschenfelde, K.H.3
  • 8
    • 0028951498 scopus 로고
    • Aspirin inhibits nuclear factor-kappa B mobilization and monocyte adhesion in stimulated human endothelial cells
    • Weber C, Erl W, Pietsch A, et al. Aspirin inhibits nuclear factor-kappa B mobilization and monocyte adhesion in stimulated human endothelial cells. Circulation. 1995;91:1914-1917.
    • (1995) Circulation , vol.91 , pp. 1914-1917
    • Weber, C.1    Erl, W.2    Pietsch, A.3
  • 9
    • 0034958206 scopus 로고    scopus 로고
    • Colonic epithelial cells induce endothelial cell expression of ICAM-1 and VCAM-1 by a NFkappaB-dependent mechanism
    • Maaser C, Schoeppner S, Kucharzik T, et al. Colonic epithelial cells induce endothelial cell expression of ICAM-1 and VCAM-1 by a NFkappaB-dependent mechanism. Clin Exp Immunol. 2001;124:208-213.
    • (2001) Clin. Exp. Immunol. , vol.124 , pp. 208-213
    • Maaser, C.1    Schoeppner, S.2    Kucharzik, T.3
  • 10
    • 0023064740 scopus 로고
    • Occurrence, absorption and metabolism of short chain fatty acids in the digestive tract of mammals
    • Bugaut M. Occurrence, absorption and metabolism of short chain fatty acids in the digestive tract of mammals. Comp Biochem Physiol B. 1987; 86:439-472.
    • (1987) Comp. Biochem. Physiol. B , vol.86 , pp. 439-472
    • Bugaut, M.1
  • 11
    • 0032499756 scopus 로고    scopus 로고
    • p21(WAF1) is required for butyrate-mediated growth inhibition of human colon cancer cells
    • Archer SY, Meng S, Shei A, et al. p21(WAF1) is required for butyrate-mediated growth inhibition of human colon cancer cells. Proc Natl Acad Sci U S A. 1998;95:6791-6796.
    • (1998) Proc. Natl. Acad. Sci. U. S. A. , vol.95 , pp. 6791-6796
    • Archer, S.Y.1    Meng, S.2    Shei, A.3
  • 12
    • 0035105352 scopus 로고    scopus 로고
    • Short chain fatty acids differentially modulate cellular phenotype and c-myc protein levels in primary human nonmalignant and malignant colonocytes
    • Emenaker NJ, Basson MD. Short chain fatty acids differentially modulate cellular phenotype and c-myc protein levels in primary human nonmalignant and malignant colonocytes. Dig Dis Sci. 2001;46:96-105.
    • (2001) Dig. Dis. Sci. , vol.46 , pp. 96-105
    • Emenaker, N.J.1    Basson, M.D.2
  • 13
    • 0035165096 scopus 로고    scopus 로고
    • Short-chain fatty acids inhibit invasive human colon cancer by modulating uPA, TIMP-1, TIMP-2, mutant p53, Bcl-2, Bax, p21 and PCNA protein expression in an in vitro cell culture model
    • Emenaker NJ, Calaf GM, Cox D, et al. Short-chain fatty acids inhibit invasive human colon cancer by modulating uPA, TIMP-1, TIMP-2, mutant p53, Bcl-2, Bax, p21 and PCNA protein expression in an in vitro cell culture model. J Nutr. 2001;131:3041S-3046S.
    • (2001) J. Nutr. , vol.131
    • Emenaker, N.J.1    Calaf, G.M.2    Cox, D.3
  • 14
    • 0034662614 scopus 로고    scopus 로고
    • Genetic reprogramming in pathways of colonic cell maturation induced by short chain fatty acids: Comparison with trichostatin A, sulindac, and curcumin and implications for chemoprevention of colon cancer
    • Mariadason JM, Corner GA, Augenlicht LH. Genetic reprogramming in pathways of colonic cell maturation induced by short chain fatty acids: comparison with trichostatin A, sulindac, and curcumin and implications for chemoprevention of colon cancer. Cancer Res. 2000;60:4561-4572.
    • (2000) Cancer Res. , vol.60 , pp. 4561-4572
    • Mariadason, J.M.1    Corner, G.A.2    Augenlicht, L.H.3
  • 15
    • 0035126973 scopus 로고    scopus 로고
    • Resistance to butyrate-induced cell differentiation and apoptosis during spontaneous Caco-2 cell differentiation
    • Mariadason JM, Velcich A, Wilson AJ, et al. Resistance to butyrate-induced cell differentiation and apoptosis during spontaneous Caco-2 cell differentiation. Gastroenterology. 2001;120:889-899.
    • (2001) Gastroenterology , vol.120 , pp. 889-899
    • Mariadason, J.M.1    Velcich, A.2    Wilson, A.J.3
  • 16
    • 0031588377 scopus 로고    scopus 로고
    • Modulation of p53 expression in cultured colonic adenoma cell lines by the naturally occurring lumenal factors butyrate and deoxycholate
    • Palmer DG, Paraskeva C, Williams AC. Modulation of p53 expression in cultured colonic adenoma cell lines by the naturally occurring lumenal factors butyrate and deoxycholate. Int J Cancer. 1997;73:702-706.
    • (1997) Int. J. Cancer , vol.73 , pp. 702-706
    • Palmer, D.G.1    Paraskeva, C.2    Williams, A.C.3
  • 17
    • 0028859161 scopus 로고
    • Apoptosis in colorectal tumor cells: Induction by the short chain fatty acids butyrate, propionate and acetate and by the bile salt deoxycholate
    • Hague A, Elder DJ, Hicks DJ, et al. Apoptosis in colorectal tumor cells: induction by the short chain fatty acids butyrate, propionate and acetate and by the bile salt deoxycholate. Int J Cancer. 1995;60:400-406.
    • (1995) Int. J. Cancer , vol.60 , pp. 400-406
    • Hague, A.1    Elder, D.J.2    Hicks, D.J.3
  • 18
    • 0030809026 scopus 로고    scopus 로고
    • bcl-2 and bak may play a pivotal role in sodium butyrate-induced apoptosis in colonic epithelial cells; however overexpression of bcl-2 does not protect against bak-mediated apoptosis
    • Hague A, Diaz GD, Hicks DJ, et al. bcl-2 and bak may play a pivotal role in sodium butyrate-induced apoptosis in colonic epithelial cells; however overexpression of bcl-2 does not protect against bak-mediated apoptosis. Int J Cancer. 1997;72:898-905.
    • (1997) Int. J. Cancer , vol.72 , pp. 898-905
    • Hague, A.1    Diaz, G.D.2    Hicks, D.J.3
  • 19
    • 0031555861 scopus 로고    scopus 로고
    • Butyrate stimulates cyclin D and p21 and inhibits cyclin-dependent kinase 2 expression in HT-29 colonic epithelial cells
    • Siavoshian S, Blottiere HM, Cherbut C, et al. Butyrate stimulates cyclin D and p21 and inhibits cyclin-dependent kinase 2 expression in HT-29 colonic epithelial cells. Biochem Biophys Res Commun. 1997;232:169-172.
    • (1997) Biochem. Biophys. Res. Commun. , vol.232 , pp. 169-172
    • Siavoshian, S.1    Blottiere, H.M.2    Cherbut, C.3
  • 20
    • 0036318268 scopus 로고    scopus 로고
    • Butyrate and aspirin in combination have an enhanced effect on apoptosis in human colorectal cancer cells
    • Menzel T, Schauber J, Kreth F, et al. Butyrate and aspirin in combination have an enhanced effect on apoptosis in human colorectal cancer cells. Eur J Cancer Prev. 2002;11:271-281.
    • (2002) Eur. J. Cancer Prev. , vol.11 , pp. 271-281
    • Menzel, T.1    Schauber, J.2    Kreth, F.3
  • 21
    • 0026495376 scopus 로고
    • Modulation of colonic epithelial cell Proliferation, histone acetylation, and luminal short chain fatty acids by variation of dietary fiber (wheat bran) in rats
    • Boffa LC, Lupton JR, Mariani MR, et al. Modulation of colonic epithelial cell Proliferation, histone acetylation, and luminal short chain fatty acids by variation of dietary fiber (wheat bran) in rats. Cancer Res. 1992;52: 5906-5912.
    • (1992) Cancer Res. , vol.52 , pp. 5906-5912
    • Boffa, L.C.1    Lupton, J.R.2    Mariani, M.R.3
  • 22
    • 0037050744 scopus 로고    scopus 로고
    • Modulation of HMG-N2 binding to chromatin by butyrate-induced acetylation in human colon adenocarcinoma cells
    • Luhrs H, Hock R, Schauber J, et al. Modulation of HMG-N2 binding to chromatin by butyrate-induced acetylation in human colon adenocarcinoma cells. Int J Cancer. 2002;97:567-573.
    • (2002) Int. J. Cancer , vol.97 , pp. 567-573
    • Luhrs, H.1    Hock, R.2    Schauber, J.3
  • 23
    • 0019128183 scopus 로고
    • Role of anaerobic bacteria in the metabolic welfare of the colonic mucosa in man
    • Roediger WE. Role of anaerobic bacteria in the metabolic welfare of the colonic mucosa in man. Gut. 1980;21:793-798.
    • (1980) Gut , vol.21 , pp. 793-798
    • Roediger, W.E.1
  • 24
    • 0025605014 scopus 로고
    • Nitrite from inflammatory cells - A cancer risk factor in ulcerative colitis?
    • Roediger WE, Lawson MJ, Radcliffe BC. Nitrite from inflammatory cells - a cancer risk factor in ulcerative colitis? Dis Colon Rectum. 1990; 33:1034-1036.
    • (1990) Dis. Colon Rectum , vol.33 , pp. 1034-1036
    • Roediger, W.E.1    Lawson, M.J.2    Radcliffe, B.C.3
  • 25
    • 0024727279 scopus 로고
    • Diversion colitis: A nutritional deficiency syndrome?
    • Agarwal VP, Schimmel EM. Diversion colitis: a nutritional deficiency syndrome? Nutr Rev. 1989;47:257-261.
    • (1989) Nutr. Rev. , vol.47 , pp. 257-261
    • Agarwal, V.P.1    Schimmel, E.M.2
  • 26
    • 0026691619 scopus 로고
    • Effect of butyrate enemas on the colonic mucosa in distal ulcerative colitis
    • Scheppach W, Sommer H, Kirchner T, et al. Effect of butyrate enemas on the colonic mucosa in distal ulcerative colitis. Gastroenterology. 1992; 103:51-56.
    • (1992) Gastroenterology , vol.103 , pp. 51-56
    • Scheppach, W.1    Sommer, H.2    Kirchner, T.3
  • 27
    • 0028798765 scopus 로고
    • Topical treatment of refractory distal ulcerative colitis with 5-ASA and sodium butyrate
    • Vernia P, Cittadini M, Caprilli R, et al. Topical treatment of refractory distal ulcerative colitis with 5-ASA and sodium butyrate. Dig Dis Sci. 1995;40:305-307.
    • (1995) Dig. Dis. Sci. , vol.40 , pp. 305-307
    • Vernia, P.1    Cittadini, M.2    Caprilli, R.3
  • 28
    • 0026738618 scopus 로고
    • Short-chain fatty acid enemas: A cost-effective alternative in the treatment of nonspecific proctosigmoiditis
    • Senagore AJ, MacKeigan JM, Scheider M, et al. Short-chain fatty acid enemas: a cost-effective alternative in the treatment of nonspecific proctosigmoiditis. Dis Colon Rectum. 1992;35:923-927.
    • (1992) Dis. Colon Rectum , vol.35 , pp. 923-927
    • Senagore, A.J.1    MacKeigan, J.M.2    Scheider, M.3
  • 29
    • 0025801210 scopus 로고
    • Rectal irrigation with short-chain fatty acids for distal ulcerative colitis. Preliminary report
    • Breuer RI, Buto SK, Christ ML, et al. Rectal irrigation with short-chain fatty acids for distal ulcerative colitis. Preliminary report. Dig Dis Sci. 1991;36:185-187.
    • (1991) Dig. Dis. Sci. , vol.36 , pp. 185-187
    • Breuer, R.I.1    Buto, S.K.2    Christ, M.L.3
  • 30
    • 0027954558 scopus 로고
    • Treatment of refractory ulcerative proctosigmoiditis with butyrate enemas
    • Steinhart AH, Brzezinski A, Baker JP. Treatment of refractory ulcerative proctosigmoiditis with butyrate enemas. Am J Gastroenterol. 1994;89: 179-183.
    • (1994) Am. J. Gastroenterol. , vol.89 , pp. 179-183
    • Steinhart, A.H.1    Brzezinski, A.2    Baker, J.P.3
  • 31
    • 0029033928 scopus 로고
    • Short-chain fatty acid topical treatment in distal ulcerative colitis
    • Vernia P, Marcheggiano A, Caprilli R, et al. Short-chain fatty acid topical treatment in distal ulcerative colitis. Aliment Pharmacol Ther. 1995;9: 309-313.
    • (1995) Aliment. Pharmacol. Ther. , vol.9 , pp. 309-313
    • Vernia, P.1    Marcheggiano, A.2    Caprilli, R.3
  • 32
    • 0024504087 scopus 로고
    • Stimulation of intestinal mucosal growth with intracolonic infusion of short-chain fatty acids
    • Kripke SA, Fox AD, Berman JM, et al. Stimulation of intestinal mucosal growth with intracolonic infusion of short-chain fatty acids. JPEN J Parenter Enteral Nutr. 1989;13:109-116.
    • (1989) JPEN J. Parenter. Enteral. Nutr. , vol.13 , pp. 109-116
    • Kripke, S.A.1    Fox, A.D.2    Berman, J.M.3
  • 33
    • 0019449068 scopus 로고
    • Effect of volatile fatty acids on blood flow and oxygen uptake by the dog colon
    • Kvietys PR, Granger DN. Effect of volatile fatty acids on blood flow and oxygen uptake by the dog colon. Gastroenterology. 1981;80:962-969.
    • (1981) Gastroenterology , vol.80 , pp. 962-969
    • Kvietys, P.R.1    Granger, D.N.2
  • 34
    • 0025601658 scopus 로고
    • Short chain fatty acids dilate isolated human colonic resistance arteries
    • Mortensen FV, Nielsen H, Mulvany MJ, et al. Short chain fatty acids dilate isolated human colonic resistance arteries. Gut. 1990;31:1391-1394.
    • (1990) Gut , vol.31 , pp. 1391-1394
    • Mortensen, F.V.1    Nielsen, H.2    Mulvany, M.J.3
  • 35
    • 0034858096 scopus 로고    scopus 로고
    • Butyrate inhibits interleukin-1-mediated nuclear factor-kappa B activation in human epithelial cells
    • Luhrs H, Gerke T, Boxberger F, et al. Butyrate inhibits interleukin-1-mediated nuclear factor-kappa B activation in human epithelial cells. Dig Dis Sci. 2001;46:1968-1973.
    • (2001) Dig. Dis. Sci. , vol.46 , pp. 1968-1973
    • Luhrs, H.1    Gerke, T.2    Boxberger, F.3
  • 36
    • 0034926541 scopus 로고    scopus 로고
    • Cytokine-activated degradation of inhibitory kappaB protein alpha is inhibited by the short-chain fatty acid butyrate
    • Luhrs H, Gerke T, Schauber J, et al. Cytokine-activated degradation of inhibitory kappaB protein alpha is inhibited by the short-chain fatty acid butyrate. Int J Colorectal Dis. 2001;16:195-201.
    • (2001) Int. J. Colorectal Dis. , vol.16 , pp. 195-201
    • Luhrs, H.1    Gerke, T.2    Schauber, J.3
  • 37
    • 0034062353 scopus 로고    scopus 로고
    • The luminal short-chain fatty acid butyrate modulates NF-kappaB activity in a human colonic epithelial cell line
    • Inan MS, Rasoulpour RJ, Yin L, et al. The luminal short-chain fatty acid butyrate modulates NF-kappaB activity in a human colonic epithelial cell line. Gastroenterology. 2000;118:724-734.
    • (2000) Gastroenterology , vol.118 , pp. 724-734
    • Inan, M.S.1    Rasoulpour, R.J.2    Yin, L.3
  • 38
    • 0035665020 scopus 로고    scopus 로고
    • Possible new role for NF-kappaB in the resolution of inflammation
    • Lawrence T, Gilroy DW, Colville-Nash PR, et al. Possible new role for NF-kappaB in the resolution of inflammation. Nat Med. 2001;7:1291-1297.
    • (2001) Nat. Med. , vol.7 , pp. 1291-1297
    • Lawrence, T.1    Gilroy, D.W.2    Colville-Nash, P.R.3
  • 39
    • 0024448304 scopus 로고
    • MyoD is a sequence-specific DNA binding protein requiring a region of myc homology to bind to the muscle creatine kinase enhancer
    • Lassar AB, Buskin JN, Lockshon D, et al. MyoD is a sequence-specific DNA binding protein requiring a region of myc homology to bind to the muscle creatine kinase enhancer. Cell. 1989;58:823-831.
    • (1989) Cell , vol.58 , pp. 823-831
    • Lassar, A.B.1    Buskin, J.N.2    Lockshon, D.3
  • 40
    • 0026093797 scopus 로고
    • One base pair change abolishes the T cell-restricted activity of a kB-like proto-enhancer element from the interleukin 2 promoter
    • Briegel K, Hentsch B, Pfeuffer I, et al. One base pair change abolishes the T cell-restricted activity of a kB-like proto-enhancer element from the interleukin 2 promoter. Nucleic Acids Res. 1991;19:5929-5936.
    • (1991) Nucleic Acids Res. , vol.19 , pp. 5929-5936
    • Briegel, K.1    Hentsch, B.2    Pfeuffer, I.3
  • 41
    • 0035861316 scopus 로고    scopus 로고
    • NF-kappaB activation for constitutive expression of VCAM-1 and ICAM-1 on B lymphocytes and plasma cells
    • Xia YF, Liu LP, Zhong CP, et al. NF-kappaB activation for constitutive expression of VCAM-1 and ICAM-1 on B lymphocytes and plasma cells. Biochem Biophys Res Commun. 2001;289:851-856.
    • (2001) Biochem. Biophys. Res. Commun. , vol.289 , pp. 851-856
    • Xia, Y.F.1    Liu, L.P.2    Zhong, C.P.3
  • 42
    • 0026729650 scopus 로고
    • TNF alpha-induced expression of endothelial adhesion molecules, ICAM-1 and VCAM-1, is linked to protein kinase C activation
    • Mattila P, Majuri ML, Mattila PS, et al. TNF alpha-induced expression of endothelial adhesion molecules, ICAM-1 and VCAM-1, is linked to protein kinase C activation. Scand J Immunol. 1992;36:159-165.
    • (1992) Scand. J. Immunol. , vol.36 , pp. 159-165
    • Mattila, P.1    Majuri, M.L.2    Mattila, P.S.3
  • 43
    • 0035958517 scopus 로고    scopus 로고
    • The role of tumor necrosis factor alpha in the pathophysiology of human multiple myeloma: Therapeutic applications
    • Hideshima T, Chauhan D, Schlossman R, et al. The role of tumor necrosis factor alpha in the pathophysiology of human multiple myeloma: therapeutic applications. Oncogene. 2001;20:4519-4527.
    • (2001) Oncogene , vol.20 , pp. 4519-4527
    • Hideshima, T.1    Chauhan, D.2    Schlossman, R.3
  • 44
    • 0036121303 scopus 로고    scopus 로고
    • Inhibition of TNF-alpha induced ICAM-1, VCAM-1 and E-selectin expression by selenium
    • Zhang F, Yu W, Hargrove JL, et al. Inhibition of TNF-alpha induced ICAM-1, VCAM-1 and E-selectin expression by selenium. Atherosclerosis. 2002;161:381-386.
    • (2002) Atherosclerosis , vol.161 , pp. 381-386
    • Zhang, F.1    Yu, W.2    Hargrove, J.L.3
  • 45
    • 0033783628 scopus 로고    scopus 로고
    • VCAM-1, but not ICAM-1 or MAd-CAM-1, immunoblockade ameliorates DSS-induced colitis in mice
    • Soriano A, Salas A, Sans M, et al. VCAM-1, but not ICAM-1 or MAd-CAM-1, immunoblockade ameliorates DSS-induced colitis in mice. Lab Invest. 2000;80:1541-1551.
    • (2000) Lab. Invest. , vol.80 , pp. 1541-1551
    • Soriano, A.1    Salas, A.2    Sans, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.